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GSE58827: Dynamics of the Mouse Liver

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Results for Hsfy2

Z-value: 0.96

Motif logo

Transcription factors associated with Hsfy2

Gene Symbol Gene ID Gene Info
ENSMUSG00000045336.4 heat shock transcription factor, Y-linked 2

Activity profile of Hsfy2 motif

Sorted Z-values of Hsfy2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_152847993 7.00 ENSMUST00000028969.8
TPX2, microtubule-associated protein homolog (Xenopus laevis)
chr2_+_152847961 5.75 ENSMUST00000164120.1
ENSMUST00000178997.1
ENSMUST00000109816.1
TPX2, microtubule-associated protein homolog (Xenopus laevis)
chr11_-_102925086 5.13 ENSMUST00000021311.9
kinesin family member 18B
chr14_-_67715585 5.11 ENSMUST00000163100.1
ENSMUST00000132705.1
ENSMUST00000124045.1
cell division cycle associated 2
chr10_+_20347788 4.92 ENSMUST00000169712.1
mitochondrial fission regulator 2
chr6_+_86628174 4.79 ENSMUST00000043400.6
aspartic peptidase, retroviral-like 1
chr8_-_53638945 4.20 ENSMUST00000047768.4
nei like 3 (E. coli)
chr11_+_58640394 4.06 ENSMUST00000075084.4
tripartite motif-containing 58
chr6_+_134929118 3.66 ENSMUST00000185152.1
ENSMUST00000184504.1
RP23-45G16.5
chr3_-_54915867 3.59 ENSMUST00000070342.3
serine rich and transmembrane domain containing 1
chr3_-_84479418 3.54 ENSMUST00000091002.1
FH2 domain containing 1
chr1_+_139454747 3.51 ENSMUST00000053364.8
ENSMUST00000097554.3
asp (abnormal spindle)-like, microcephaly associated (Drosophila)
chr10_-_79874211 3.50 ENSMUST00000167897.1
cDNA sequence BC005764
chr11_+_11686213 3.33 ENSMUST00000076700.4
ENSMUST00000048122.6
IKAROS family zinc finger 1
chr11_+_32205411 3.27 ENSMUST00000039601.3
ENSMUST00000149043.1
small nuclear ribonucleoprotein 25 (U11/U12)
chr4_+_121039385 3.24 ENSMUST00000030372.5
collagen, type IX, alpha 2
chr3_-_20242173 3.15 ENSMUST00000001921.1
carboxypeptidase A3, mast cell
chr7_+_13733502 2.91 ENSMUST00000086148.6
sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 2
chr9_-_64172879 2.85 ENSMUST00000176299.1
ENSMUST00000130127.1
ENSMUST00000176794.1
ENSMUST00000177045.1
zwilch kinetochore protein
chr13_-_37050237 2.82 ENSMUST00000164727.1
coagulation factor XIII, A1 subunit
chr10_-_79874233 2.69 ENSMUST00000166023.1
ENSMUST00000167707.1
ENSMUST00000165601.1
cDNA sequence BC005764
chr4_+_126556935 2.58 ENSMUST00000048391.8
claspin
chr3_+_107896247 2.55 ENSMUST00000169365.1
glutathione S-transferase, mu 5
chr8_-_22185758 2.52 ENSMUST00000046916.7
cytoskeleton associated protein 2
chr7_-_126704522 2.43 ENSMUST00000135087.1
coronin, actin binding protein 1A
chr3_+_108383829 2.40 ENSMUST00000090561.3
ENSMUST00000102629.1
ENSMUST00000128089.1
proline/serine-rich coiled-coil 1
chr9_-_39603635 2.29 ENSMUST00000119722.1
expressed sequence AW551984
chr7_-_127993831 2.25 ENSMUST00000033056.3
PYD and CARD domain containing
chr1_-_93342734 2.20 ENSMUST00000027493.3
PAS domain containing serine/threonine kinase
chr4_+_126556994 2.06 ENSMUST00000147675.1
claspin
chr17_+_47593516 2.05 ENSMUST00000182874.1
cyclin D3
chr14_-_31577318 2.01 ENSMUST00000112027.2
collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
chr9_-_72491939 2.00 ENSMUST00000185151.1
ENSMUST00000085358.5
ENSMUST00000184125.1
ENSMUST00000183574.1
ENSMUST00000184831.1
testis expressed gene 9
chr15_+_44457522 1.97 ENSMUST00000166957.1
ENSMUST00000038336.5
polycystic kidney and hepatic disease 1-like 1
chr11_+_5569679 1.95 ENSMUST00000109856.1
ENSMUST00000109855.1
ENSMUST00000118112.2
ankyrin repeat domain 36
chr1_+_191063001 1.94 ENSMUST00000076952.5
ENSMUST00000139340.1
ENSMUST00000078259.6
NSL1, MIND kinetochore complex component, homolog (S. cerevisiae)
chr6_+_123229843 1.94 ENSMUST00000112554.2
ENSMUST00000024118.4
ENSMUST00000117130.1
C-type lectin domain family 4, member n
chr3_-_86920830 1.94 ENSMUST00000029719.8
doublecortin-like kinase 2
chr17_+_47593444 1.90 ENSMUST00000182209.1
cyclin D3
chr9_+_106281061 1.84 ENSMUST00000072206.6
POC1 centriolar protein homolog A (Chlamydomonas)
chr10_+_45577811 1.81 ENSMUST00000037044.6
HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1
chr15_-_80083374 1.78 ENSMUST00000081650.7
ribosomal protein L3
chr9_-_36726374 1.75 ENSMUST00000172702.2
ENSMUST00000172742.1
ENSMUST00000034625.5
checkpoint kinase 1
chr17_+_26917091 1.74 ENSMUST00000078961.4
kinesin family member C5B
chr7_+_43351378 1.73 ENSMUST00000012798.7
ENSMUST00000122423.1
ENSMUST00000121494.1
sialic acid binding Ig-like lectin 5
chr6_+_48589445 1.65 ENSMUST00000064744.3
predicted gene 5111
chr9_-_32344237 1.65 ENSMUST00000034533.5
potassium inwardly-rectifying channel, subfamily J, member 5
chr14_+_79451791 1.63 ENSMUST00000100359.1
kelch repeat and BTB (POZ) domain containing 6
chr7_-_14123042 1.59 ENSMUST00000098809.2
sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 3
chr12_-_55014329 1.58 ENSMUST00000172875.1
bromodomain adjacent to zinc finger domain 1A
chr10_+_79664553 1.57 ENSMUST00000020554.6
mucosal vascular addressin cell adhesion molecule 1
chr13_-_95525239 1.53 ENSMUST00000022185.8
coagulation factor II (thrombin) receptor-like 1
chr1_-_190978954 1.48 ENSMUST00000047409.6
vasohibin 2
chr15_+_103240405 1.47 ENSMUST00000036004.9
ENSMUST00000087351.7
heterogeneous nuclear ribonucleoprotein A1
chr3_+_129878571 1.47 ENSMUST00000029629.8
phospholipase A2, group XIIA
chr15_-_66801577 1.43 ENSMUST00000168589.1
src-like adaptor
chr13_+_5861489 1.43 ENSMUST00000000080.6
Kruppel-like factor 6
chr6_+_86404257 1.40 ENSMUST00000095752.2
ENSMUST00000130967.1
cytotoxic granule-associated RNA binding protein 1
chr14_+_60378242 1.38 ENSMUST00000022561.6
APC membrane recruitment 2
chrX_+_94636066 1.37 ENSMUST00000096368.3
G1 to S phase transition 2
chr15_+_38933142 1.37 ENSMUST00000163313.1
brain and acute leukemia, cytoplasmic
chr5_+_108132885 1.36 ENSMUST00000047677.7
coiled-coil domain containing 18
chr6_+_86404219 1.36 ENSMUST00000095754.3
ENSMUST00000095753.2
cytotoxic granule-associated RNA binding protein 1
chr1_-_190979280 1.35 ENSMUST00000166139.1
vasohibin 2
chr13_-_120027011 1.35 ENSMUST00000177659.1
predicted gene, 21370
chr2_+_172393900 1.33 ENSMUST00000109136.2
Cas scaffolding protein family member 4
chr1_-_33669745 1.33 ENSMUST00000027312.9
DNA primase, p58 subunit
chr4_+_108879130 1.33 ENSMUST00000106651.2
RAB3B, member RAS oncogene family
chr2_-_181693810 1.32 ENSMUST00000108776.1
ENSMUST00000108771.1
ENSMUST00000108779.1
ENSMUST00000108769.1
ENSMUST00000108772.1
ENSMUST00000002532.2
regulator of G-protein signaling 19
chr11_+_102881204 1.31 ENSMUST00000021307.3
ENSMUST00000159834.1
coiled-coil domain containing 103
chr4_+_108879063 1.30 ENSMUST00000106650.2
RAB3B, member RAS oncogene family
chr11_-_11462408 1.29 ENSMUST00000020413.3
zona pellucida binding protein
chr7_-_112159034 1.28 ENSMUST00000033036.5
dickkopf homolog 3 (Xenopus laevis)
chr2_+_119799514 1.26 ENSMUST00000028763.9
TYRO3 protein tyrosine kinase 3
chr8_+_60655540 1.25 ENSMUST00000034066.3
microfibrillar-associated protein 3-like
chr6_+_49367739 1.24 ENSMUST00000060561.8
ENSMUST00000121903.1
ENSMUST00000134786.1
family with sequence similarity 221, member A
chrX_+_162901567 1.21 ENSMUST00000112303.1
ENSMUST00000033727.7
cytidine 5'-triphosphate synthase 2
chr9_+_64173364 1.21 ENSMUST00000034966.7
ribosomal protein L4
chr11_+_62248977 1.19 ENSMUST00000018644.2
adenosine A2b receptor
chr3_-_152340350 1.19 ENSMUST00000073089.6
ENSMUST00000068243.6
family with sequence similarity 73, member A
chr19_-_11660516 1.18 ENSMUST00000135994.1
ENSMUST00000121793.1
ENSMUST00000069681.3
placenta-specific 1-like
chrX_+_159627265 1.17 ENSMUST00000112456.2
SH3-domain kinase binding protein 1
chr6_-_40951826 1.17 ENSMUST00000073642.5
predicted gene 4744
chrX_-_133688978 1.17 ENSMUST00000149154.1
ENSMUST00000167944.1
protocadherin 19
chr5_-_149051604 1.16 ENSMUST00000093196.4
high mobility group box 1
chr17_-_14694223 1.15 ENSMUST00000170872.1
thrombospondin 2
chr11_-_109828021 1.15 ENSMUST00000020941.4
RIKEN cDNA 1700012B07 gene
chr5_+_31697960 1.15 ENSMUST00000114515.2
brain and reproductive organ-expressed protein
chr7_+_28692849 1.15 ENSMUST00000039998.4
F-box protein 27
chr19_+_18713192 1.14 ENSMUST00000062753.2
RIKEN cDNA D030056L22 gene
chr13_+_55445301 1.14 ENSMUST00000001115.8
ENSMUST00000099482.3
G protein-coupled receptor kinase 6
chr13_+_44729535 1.14 ENSMUST00000174068.1
jumonji, AT rich interactive domain 2
chr7_+_28693032 1.13 ENSMUST00000151227.1
ENSMUST00000108281.1
F-box protein 27
chr11_+_32205483 1.10 ENSMUST00000121182.1
small nuclear ribonucleoprotein 25 (U11/U12)
chr4_-_149126688 1.08 ENSMUST00000030815.2
cortistatin
chr5_-_113015473 1.07 ENSMUST00000065167.4
adrenergic receptor kinase, beta 2
chrX_+_159840463 1.06 ENSMUST00000112451.1
ENSMUST00000112453.2
SH3-domain kinase binding protein 1
chr11_-_40733373 1.06 ENSMUST00000020579.8
hyaluronan mediated motility receptor (RHAMM)
chr14_-_99099701 1.05 ENSMUST00000042471.9
DIS3 mitotic control homolog (S. cerevisiae)
chr7_+_28440927 1.04 ENSMUST00000078845.6
glia maturation factor, gamma
chr17_+_50698525 1.03 ENSMUST00000061681.7
predicted gene 7334
chr5_-_31241215 1.02 ENSMUST00000068997.3
predicted gene 9970
chr5_+_31698050 1.01 ENSMUST00000114507.3
ENSMUST00000063813.4
ENSMUST00000071531.5
ENSMUST00000131995.1
brain and reproductive organ-expressed protein
chr1_-_149961230 1.00 ENSMUST00000070200.8
phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr7_+_28441026 1.00 ENSMUST00000135686.1
glia maturation factor, gamma
chr9_-_44344159 1.00 ENSMUST00000077353.7
hydroxymethylbilane synthase
chr9_-_41004599 0.99 ENSMUST00000180384.1
cytotoxic and regulatory T cell molecule
chr11_+_3330401 0.98 ENSMUST00000045153.4
phosphoinositide-3-kinase interacting protein 1
chr9_-_41004562 0.96 ENSMUST00000034519.6
cytotoxic and regulatory T cell molecule
chr19_+_18713225 0.94 ENSMUST00000055792.7
RIKEN cDNA D030056L22 gene
chr18_-_37644185 0.93 ENSMUST00000066272.4
TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr7_+_29170345 0.92 ENSMUST00000033886.7
gametogenetin
chr10_-_80918212 0.92 ENSMUST00000057623.7
ENSMUST00000179022.1
lamin B2
chr13_-_105271039 0.91 ENSMUST00000069686.6
ring finger protein 180
chr4_-_140845770 0.89 ENSMUST00000026378.3
peptidyl arginine deiminase, type I
chr11_+_3330781 0.89 ENSMUST00000136536.1
ENSMUST00000093399.4
phosphoinositide-3-kinase interacting protein 1
chr3_-_51396716 0.89 ENSMUST00000141156.1
mitochondria localized glutamic acid rich protein
chr6_-_56362356 0.89 ENSMUST00000044505.7
ENSMUST00000166102.1
ENSMUST00000164037.1
ENSMUST00000114327.2
phosphodiesterase 1C
chr4_-_41464816 0.89 ENSMUST00000108055.2
ENSMUST00000154535.1
ENSMUST00000030148.5
kinesin family member 24
chr11_+_44518959 0.87 ENSMUST00000019333.3
ring finger protein 145
chr15_+_92344359 0.87 ENSMUST00000181901.1
predicted gene, 26760
chr9_-_106096776 0.87 ENSMUST00000121963.1
collagen, type VI, alpha 4
chr4_+_119195353 0.86 ENSMUST00000106345.2
coiled-coil domain containing 23
chr17_-_33685386 0.85 ENSMUST00000139302.1
ENSMUST00000087582.5
ENSMUST00000114385.2
heterogeneous nuclear ribonucleoprotein M
chr9_-_49798729 0.85 ENSMUST00000166811.2
neural cell adhesion molecule 1
chr8_+_94214567 0.85 ENSMUST00000079961.6
nucleoporin 93
chr8_-_4325096 0.83 ENSMUST00000098950.4
ELAV (embryonic lethal, abnormal vision)-like 1 (Hu antigen R)
chr9_-_37613715 0.81 ENSMUST00000002013.9
sperm autoantigenic protein 17
chr3_-_15838643 0.81 ENSMUST00000148194.1
signal-regulatory protein beta 1C
chr7_+_3704025 0.81 ENSMUST00000108623.1
ENSMUST00000139818.1
ENSMUST00000108625.1
ribosomal protein S9
chr13_+_23752267 0.80 ENSMUST00000091703.2
histone cluster 1, H3b
chr9_-_45984816 0.80 ENSMUST00000172450.1
platelet-activating factor acetylhydrolase, isoform 1b, subunit 2
chr7_-_14562171 0.78 ENSMUST00000181796.1
vomeronasal 1 receptor 90
chr8_-_84840627 0.78 ENSMUST00000003911.6
ENSMUST00000109761.2
ENSMUST00000128035.1
RAD23a homolog (S. cerevisiae)
chr1_-_21961581 0.77 ENSMUST00000029667.6
ENSMUST00000173058.1
ENSMUST00000173404.1
potassium voltage-gated channel, subfamily Q, member 5
chr13_+_51645232 0.77 ENSMUST00000075853.5
CDC28 protein kinase regulatory subunit 2
chr19_+_46396885 0.76 ENSMUST00000039922.6
ENSMUST00000111867.2
ENSMUST00000120778.1
suppressor of fused homolog (Drosophila)
chr11_-_102880925 0.76 ENSMUST00000021306.7
elongation factor Tu GTP binding domain containing 2
chr10_-_13324160 0.75 ENSMUST00000105545.4
phosphatase and actin regulator 2
chr12_-_110845184 0.75 ENSMUST00000180988.1
predicted gene, 26912
chr17_+_35241838 0.75 ENSMUST00000173731.1
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
chr3_-_59220150 0.75 ENSMUST00000170388.1
purinergic receptor P2Y, G-protein coupled 12
chr11_-_20332654 0.74 ENSMUST00000004634.6
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr9_+_95857597 0.74 ENSMUST00000034980.7
ataxia telangiectasia and Rad3 related
chr14_-_54781886 0.73 ENSMUST00000022787.6
solute carrier family 7 (cationic amino acid transporter, y+ system), member 8
chr7_+_60155538 0.73 ENSMUST00000057611.4
predicted pseudogene 7367
chr8_+_60632856 0.73 ENSMUST00000160719.1
microfibrillar-associated protein 3-like
chr1_-_93801840 0.73 ENSMUST00000112890.2
ENSMUST00000027503.7
deoxythymidylate kinase
chr4_+_3940747 0.72 ENSMUST00000119403.1
coiled-coil-helix-coiled-coil-helix domain containing 7
chrX_+_101274198 0.71 ENSMUST00000117203.1
ENSMUST00000087948.4
ENSMUST00000087956.5
mediator of RNA polymerase II transcription, subunit 12 homolog (yeast)
chr9_-_83146601 0.71 ENSMUST00000162246.2
ENSMUST00000161796.2
high mobility group nucleosomal binding domain 3
chr14_+_56402656 0.71 ENSMUST00000095793.1
ring finger protein 17
chr9_-_107289847 0.70 ENSMUST00000035194.2
mitogen-activated protein kinase-activated protein kinase 3
chr2_-_151980135 0.70 ENSMUST00000062047.5
family with sequence similarity 110, member A
chr5_-_123721007 0.68 ENSMUST00000031376.7
zinc finger, CCHC domain containing 8
chrX_+_101274023 0.67 ENSMUST00000117706.1
mediator of RNA polymerase II transcription, subunit 12 homolog (yeast)
chr17_-_31129602 0.65 ENSMUST00000024827.4
trefoil factor 3, intestinal
chr1_+_75546258 0.65 ENSMUST00000124341.1
solute carrier family 4 (anion exchanger), member 3
chr4_+_5644084 0.65 ENSMUST00000054857.6
family with sequence similarity 110, member B
chr11_-_102880981 0.65 ENSMUST00000107060.1
elongation factor Tu GTP binding domain containing 2
chr7_+_3703979 0.64 ENSMUST00000006496.8
ribosomal protein S9
chrX_-_73824938 0.64 ENSMUST00000114438.2
ENSMUST00000002080.5
PDZ domain containing 4
chr6_-_83441674 0.64 ENSMUST00000089622.4
tet methylcytosine dioxygenase 3
chr5_+_31697665 0.64 ENSMUST00000080598.7
brain and reproductive organ-expressed protein
chr17_+_35241746 0.63 ENSMUST00000068056.5
ENSMUST00000174757.1
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
chr7_+_3704307 0.63 ENSMUST00000108624.1
ENSMUST00000126562.1
ribosomal protein S9
chr7_+_128246812 0.63 ENSMUST00000164710.1
ENSMUST00000070656.5
transforming growth factor beta 1 induced transcript 1
chr8_+_84872105 0.63 ENSMUST00000136026.1
ENSMUST00000170296.1
synaptonemal complex central element protein 2
chr16_+_31933851 0.62 ENSMUST00000052174.2
phosphatidylinositol glycan anchor biosynthesis, class Z
chr10_-_7663245 0.62 ENSMUST00000163085.1
ENSMUST00000159917.1
protein-L-isoaspartate (D-aspartate) O-methyltransferase 1
chr9_+_44134562 0.61 ENSMUST00000034650.8
ENSMUST00000098852.2
melanoma cell adhesion molecule
chr3_-_61365951 0.61 ENSMUST00000066298.2
RIKEN cDNA B430305J03 gene
chr15_-_32244632 0.60 ENSMUST00000181536.1
RIKEN cDNA 0610007N19
chr6_+_129397478 0.60 ENSMUST00000112081.2
ENSMUST00000112079.2
C-type lectin domain family 1, member b
chr1_-_85254548 0.60 ENSMUST00000161685.1
RIKEN cDNA C130026I21 gene
chrX_-_57393020 0.60 ENSMUST00000143310.1
ENSMUST00000098470.2
ENSMUST00000114726.1
RNA binding motif protein, X chromosome
chr9_+_88581036 0.60 ENSMUST00000164661.2
tripartite motif-containing 43A
chr11_-_70410010 0.59 ENSMUST00000019065.3
ENSMUST00000135148.1
proline, glutamic acid and leucine rich protein 1
chr17_-_24205514 0.59 ENSMUST00000097376.3
ENSMUST00000168410.2
ENSMUST00000167791.2
ENSMUST00000040474.7
TBC1 domain family, member 24
chr5_+_137629169 0.58 ENSMUST00000176667.1
leucine-rich repeats and calponin homology (CH) domain containing 4
chr14_+_75016027 0.58 ENSMUST00000036072.7
RIKEN cDNA 5031414D18 gene
chr6_-_92244645 0.57 ENSMUST00000006046.4
thyrotropin releasing hormone
chr8_+_60632818 0.57 ENSMUST00000161421.1
microfibrillar-associated protein 3-like
chr1_+_44551483 0.57 ENSMUST00000074525.3
GULP, engulfment adaptor PTB domain containing 1
chr18_-_61259987 0.56 ENSMUST00000170335.2
ribosomal protein S2, pseudogene 10
chr16_-_64479148 0.56 ENSMUST00000089279.4
casein kinase 2, alpha prime interacting protein
chr12_+_99964499 0.56 ENSMUST00000177549.1
ENSMUST00000160413.1
ENSMUST00000162221.1
ENSMUST00000049788.8
potassium channel, subfamily K, member 13
chr12_-_102743625 0.56 ENSMUST00000173760.2
ENSMUST00000178384.1
modulator of apoptosis 1
chr8_-_35495487 0.55 ENSMUST00000033927.6
exoribonuclease 1
chr2_+_25180737 0.55 ENSMUST00000104999.2
Notch-regulated ankyrin repeat protein
chr14_+_70100083 0.55 ENSMUST00000022680.7
bridging integrator 3
chr16_+_13780699 0.54 ENSMUST00000023363.6
RRN3 RNA polymerase I transcription factor homolog (yeast)
chr2_-_154892887 0.53 ENSMUST00000099173.4
eukaryotic translation initiation factor 2, subunit 2 (beta)
chr3_+_122924353 0.52 ENSMUST00000106429.3
RIKEN cDNA 1810037I17 gene
chr12_+_38781093 0.51 ENSMUST00000161513.1
ets variant gene 1
chr6_-_129717132 0.51 ENSMUST00000088046.1
killer cell lectin-like receptor family I member 1
chr10_+_7667503 0.51 ENSMUST00000040135.8
nucleoporin 43
chr3_+_14533817 0.50 ENSMUST00000169079.1
ENSMUST00000091325.3
leucine rich repeat and coiled-coil domain containing 1
chr15_+_82016420 0.50 ENSMUST00000168581.1
ENSMUST00000170630.1
ENSMUST00000164779.1
X-ray repair complementing defective repair in Chinese hamster cells 6
chr2_-_154892782 0.49 ENSMUST00000166171.1
ENSMUST00000161172.1
eukaryotic translation initiation factor 2, subunit 2 (beta)

Network of associatons between targets according to the STRING database.

First level regulatory network of Hsfy2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.3 GO:0045660 positive regulation of neutrophil differentiation(GO:0045660)
0.8 2.3 GO:0002582 myeloid dendritic cell activation involved in immune response(GO:0002277) positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588)
0.7 2.0 GO:0071846 actin filament debranching(GO:0071846)
0.7 2.6 GO:0097494 positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944) regulation of vesicle size(GO:0097494)
0.6 1.9 GO:0002355 detection of tumor cell(GO:0002355)
0.6 3.2 GO:0051661 maintenance of centrosome location(GO:0051661)
0.5 1.5 GO:1900135 positive regulation of eosinophil degranulation(GO:0043311) regulation of neutrophil mediated cytotoxicity(GO:0070948) regulation of neutrophil mediated killing of symbiont cell(GO:0070949) positive regulation of renin secretion into blood stream(GO:1900135) positive regulation of eosinophil activation(GO:1902568)
0.5 1.9 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.5 1.4 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.4 4.6 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.4 15.4 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.4 2.4 GO:0032796 uropod organization(GO:0032796)
0.4 1.2 GO:0002270 plasmacytoid dendritic cell activation(GO:0002270)
0.4 2.5 GO:0070458 detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
0.3 2.0 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.3 1.3 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.3 1.8 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.3 1.1 GO:0010360 negative regulation of anion channel activity(GO:0010360)
0.3 0.9 GO:0001928 regulation of exocyst assembly(GO:0001928)
0.3 2.8 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.3 1.9 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.3 1.8 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.3 1.0 GO:0071043 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.3 1.3 GO:0032345 negative regulation of glucocorticoid metabolic process(GO:0031944) negative regulation of glucocorticoid biosynthetic process(GO:0031947) negative regulation of aldosterone metabolic process(GO:0032345) negative regulation of aldosterone biosynthetic process(GO:0032348) negative regulation of cortisol biosynthetic process(GO:2000065)
0.3 1.8 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.2 0.7 GO:1904882 telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.2 0.7 GO:0009197 dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate metabolic process(GO:0009138) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077)
0.2 1.4 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
0.2 2.8 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.2 1.2 GO:0002678 positive regulation of chronic inflammatory response(GO:0002678)
0.2 2.2 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719)
0.2 1.4 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.2 0.7 GO:1904124 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.2 0.7 GO:0015825 L-serine transport(GO:0015825)
0.2 0.5 GO:0009826 unidimensional cell growth(GO:0009826)
0.2 4.0 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.2 0.9 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.2 0.5 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.2 2.3 GO:0060923 cardiac muscle cell fate commitment(GO:0060923)
0.2 0.9 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.2 1.0 GO:2001280 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.2 0.5 GO:2000373 CRD-mediated mRNA stabilization(GO:0070934) regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
0.2 1.3 GO:0071907 determination of digestive tract left/right asymmetry(GO:0071907)
0.2 1.1 GO:0021775 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.2 1.0 GO:0001844 protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:0001844)
0.2 0.8 GO:0045356 positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.1 0.7 GO:0044351 macropinocytosis(GO:0044351)
0.1 0.4 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.1 0.4 GO:1990523 negative regulation of SMAD protein import into nucleus(GO:0060392) endothelial cell-cell adhesion(GO:0071603) negative regulation of sensory perception of pain(GO:1904057) bone regeneration(GO:1990523)
0.1 0.4 GO:0043096 germinal center B cell differentiation(GO:0002314) adenosine catabolic process(GO:0006154) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) purine nucleobase salvage(GO:0043096) hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101) purine deoxyribonucleoside metabolic process(GO:0046122) negative regulation of mucus secretion(GO:0070256)
0.1 0.4 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.1 8.5 GO:0007019 microtubule depolymerization(GO:0007019)
0.1 0.4 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.1 0.4 GO:0090004 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.1 0.6 GO:0001692 histamine metabolic process(GO:0001692)
0.1 0.9 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.1 0.4 GO:0014738 regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900) negative regulation of interleukin-8 biosynthetic process(GO:0045415)
0.1 0.5 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.1 0.5 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.1 1.3 GO:0060068 vagina development(GO:0060068)
0.1 4.2 GO:0006284 base-excision repair(GO:0006284)
0.1 0.3 GO:0006667 sphinganine metabolic process(GO:0006667)
0.1 1.2 GO:0006241 CTP biosynthetic process(GO:0006241) CTP metabolic process(GO:0046036)
0.1 1.0 GO:0018065 protein-cofactor linkage(GO:0018065)
0.1 1.3 GO:0001675 acrosome assembly(GO:0001675)
0.1 0.6 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 0.2 GO:0071544 diphosphoinositol polyphosphate catabolic process(GO:0071544)
0.1 2.8 GO:0045026 plasma membrane fusion(GO:0045026)
0.1 1.9 GO:0021860 pyramidal neuron development(GO:0021860)
0.1 0.5 GO:0046813 T cell antigen processing and presentation(GO:0002457) receptor-mediated virion attachment to host cell(GO:0046813)
0.1 1.1 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.1 0.3 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.1 1.2 GO:0036093 germ cell proliferation(GO:0036093)
0.1 4.9 GO:0009060 aerobic respiration(GO:0009060)
0.1 0.6 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.1 0.6 GO:0031125 rRNA 3'-end processing(GO:0031125)
0.1 4.3 GO:0035307 positive regulation of protein dephosphorylation(GO:0035307)
0.1 0.9 GO:0042415 norepinephrine metabolic process(GO:0042415)
0.1 0.9 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 1.8 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.1 0.4 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.1 1.1 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.1 0.6 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.1 0.9 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 0.2 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.1 0.5 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.0 0.5 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.6 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 1.1 GO:0045187 regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.0 1.5 GO:1903963 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 0.6 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.6 GO:0080111 DNA demethylation(GO:0080111)
0.0 0.9 GO:0035067 negative regulation of histone acetylation(GO:0035067)
0.0 0.6 GO:0046498 S-adenosylhomocysteine metabolic process(GO:0046498)
0.0 0.2 GO:0060279 positive regulation of ovulation(GO:0060279)
0.0 0.6 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 2.4 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.0 0.1 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.3 GO:0009301 snRNA transcription(GO:0009301)
0.0 0.7 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.3 GO:0035608 protein deglutamylation(GO:0035608)
0.0 0.3 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 1.1 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 0.2 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 1.4 GO:0034113 heterotypic cell-cell adhesion(GO:0034113)
0.0 0.8 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.2 GO:0044789 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0 1.8 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.8 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.0 0.6 GO:0030220 platelet formation(GO:0030220)
0.0 0.5 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.0 0.0 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.0 0.2 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 1.2 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.5 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.7 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.8 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.0 0.5 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.6 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 1.2 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.3 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.2 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.9 GO:0007566 embryo implantation(GO:0007566)
0.0 1.2 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.0 1.3 GO:0051028 mRNA transport(GO:0051028)
0.0 1.2 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.6 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.8 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 3.2 GO:0043588 skin development(GO:0043588)
0.0 1.4 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.0 1.1 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 17.9 GO:0005818 aster(GO:0005818)
1.0 2.9 GO:1990423 RZZ complex(GO:1990423)
0.9 3.5 GO:0036449 microtubule minus-end(GO:0036449)
0.8 3.2 GO:0005594 collagen type IX trimer(GO:0005594)
0.6 2.3 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.5 1.4 GO:0018444 translation release factor complex(GO:0018444)
0.4 1.6 GO:0008623 CHRAC(GO:0008623)
0.3 2.8 GO:0097165 nuclear stress granule(GO:0097165)
0.3 1.3 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.2 1.4 GO:0005687 U4 snRNP(GO:0005687)
0.2 3.3 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.2 3.4 GO:0035686 sperm fibrous sheath(GO:0035686)
0.2 0.5 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.2 0.8 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.2 4.6 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.1 0.8 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.1 0.9 GO:0005638 lamin filament(GO:0005638)
0.1 0.5 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.1 0.4 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.1 1.0 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 0.9 GO:0042382 paraspeckles(GO:0042382)
0.1 0.6 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 2.0 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.1 1.0 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.1 5.7 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 2.1 GO:0032426 stereocilium tip(GO:0032426)
0.1 0.6 GO:0001940 male pronucleus(GO:0001940)
0.1 1.0 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 1.3 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.1 0.6 GO:0061574 ASAP complex(GO:0061574)
0.1 0.8 GO:0032009 early phagosome(GO:0032009)
0.1 1.0 GO:0031143 pseudopodium(GO:0031143)
0.1 0.5 GO:0000801 central element(GO:0000801)
0.1 0.2 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.0 0.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 1.2 GO:0031091 platelet alpha granule(GO:0031091)
0.0 0.3 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 2.6 GO:0005871 kinesin complex(GO:0005871)
0.0 2.2 GO:0005876 spindle microtubule(GO:0005876)
0.0 1.1 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 2.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 3.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 2.5 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.6 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.8 GO:0042588 zymogen granule(GO:0042588)
0.0 1.2 GO:0016592 mediator complex(GO:0016592)
0.0 0.3 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.7 GO:0001741 XY body(GO:0001741)
0.0 0.2 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.0 1.7 GO:0005657 replication fork(GO:0005657)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.8 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.5 GO:0032279 asymmetric synapse(GO:0032279)
0.0 1.6 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.6 GO:0030315 T-tubule(GO:0030315)
0.0 2.0 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.3 GO:0005845 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 2.1 GO:0005814 centriole(GO:0005814)
0.0 0.4 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.4 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.5 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 2.8 GO:0005681 spliceosomal complex(GO:0005681)
0.0 0.1 GO:0044299 C-fiber(GO:0044299)
0.0 0.6 GO:0001772 immunological synapse(GO:0001772)
0.0 2.4 GO:0001650 fibrillar center(GO:0001650)
0.0 1.2 GO:0005643 nuclear pore(GO:0005643)
0.0 1.6 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.4 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.2 GO:0031011 Ino80 complex(GO:0031011)
0.0 0.4 GO:0005921 gap junction(GO:0005921)
0.0 0.1 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.7 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.7 GO:0005758 mitochondrial intermembrane space(GO:0005758)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 12.7 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.8 4.2 GO:0000405 bubble DNA binding(GO:0000405)
0.8 4.6 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.6 1.8 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.5 1.6 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.5 1.9 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.4 1.2 GO:0000401 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
0.4 1.5 GO:0015057 thrombin receptor activity(GO:0015057)
0.4 2.8 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.3 2.1 GO:1990932 5.8S rRNA binding(GO:1990932)
0.3 1.2 GO:0003883 CTP synthase activity(GO:0003883)
0.3 1.1 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.3 1.4 GO:0030621 U4 snRNA binding(GO:0030621)
0.3 0.8 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.3 2.3 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.2 0.5 GO:0034046 poly(G) binding(GO:0034046)
0.2 0.7 GO:0050145 uridylate kinase activity(GO:0009041) nucleoside phosphate kinase activity(GO:0050145)
0.2 0.9 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.2 3.0 GO:0008097 5S rRNA binding(GO:0008097)
0.2 1.6 GO:0004027 alcohol sulfotransferase activity(GO:0004027)
0.2 1.6 GO:0098634 protein binding involved in cell-matrix adhesion(GO:0098634)
0.2 0.6 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.2 0.8 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.2 0.6 GO:0071207 histone pre-mRNA stem-loop binding(GO:0071207)
0.2 0.9 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.2 0.5 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.2 1.9 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.2 1.4 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.2 4.7 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.2 1.0 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.2 2.0 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.4 GO:0071209 U7 snRNA binding(GO:0071209)
0.1 0.7 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.1 0.9 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.7 GO:0032405 MutLalpha complex binding(GO:0032405) MutSalpha complex binding(GO:0032407)
0.1 1.0 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 2.4 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 3.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 0.4 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.1 0.6 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 0.4 GO:0004092 carnitine O-acetyltransferase activity(GO:0004092)
0.1 0.3 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.1 3.6 GO:0017091 AU-rich element binding(GO:0017091)
0.1 3.3 GO:0008187 poly-pyrimidine tract binding(GO:0008187)
0.1 2.6 GO:0031489 myosin V binding(GO:0031489)
0.1 0.5 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 2.5 GO:0043295 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.1 0.4 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.1 4.4 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1 0.6 GO:0048495 Roundabout binding(GO:0048495)
0.1 0.8 GO:0035197 siRNA binding(GO:0035197)
0.1 8.0 GO:0003777 microtubule motor activity(GO:0003777)
0.1 0.4 GO:0080084 RNA polymerase III type 1 promoter DNA binding(GO:0001030) RNA polymerase III type 2 promoter DNA binding(GO:0001031) RNA polymerase III type 3 promoter DNA binding(GO:0001032) 5S rDNA binding(GO:0080084)
0.1 0.7 GO:0022858 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.1 0.3 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 0.2 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798)
0.1 0.3 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
0.1 0.9 GO:1990405 protein antigen binding(GO:1990405)
0.1 0.7 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 1.3 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 0.2 GO:0036033 mediator complex binding(GO:0036033)
0.1 1.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.5 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 1.5 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 2.9 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 1.1 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 1.1 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.2 GO:1902282 ATP-activated inward rectifier potassium channel activity(GO:0015272) voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.0 0.2 GO:0034431 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.0 0.9 GO:0030275 LRR domain binding(GO:0030275)
0.0 1.4 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 1.1 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.4 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.7 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.8 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 0.4 GO:0071253 connexin binding(GO:0071253)
0.0 0.6 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.3 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.2 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 1.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 1.4 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 1.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 1.3 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.0 0.4 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 1.1 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 1.8 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.3 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.9 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.7 GO:0005112 Notch binding(GO:0005112)
0.0 1.9 GO:0008013 beta-catenin binding(GO:0008013)
0.0 1.0 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.3 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.2 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.0 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.0 0.1 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.3 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.2 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 2.2 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.2 GO:0002162 dystroglycan binding(GO:0002162)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 12.7 PID AURORA A PATHWAY Aurora A signaling
0.2 1.8 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 5.4 PID ATR PATHWAY ATR signaling pathway
0.1 2.8 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 1.6 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 3.9 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 2.0 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 1.2 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 1.2 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 2.8 NABA COLLAGENS Genes encoding collagen proteins
0.0 1.6 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 1.8 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 1.1 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.4 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.3 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.6 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.7 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 1.2 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.8 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 1.3 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 1.1 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 1.7 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.8 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.8 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.5 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 1.3 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 0.7 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.9 PID FGF PATHWAY FGF signaling pathway
0.0 0.7 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.8 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.4 PID CONE PATHWAY Visual signal transduction: Cones
0.0 1.4 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.2 ST GA12 PATHWAY G alpha 12 Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.5 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.2 2.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 2.5 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 1.3 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1 1.0 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 1.5 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 1.9 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.1 4.0 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 1.1 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 1.2 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 1.9 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 4.2 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 3.6 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 0.8 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1 0.8 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1 2.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 2.2 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.1 1.8 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 4.4 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 0.6 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 2.4 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 3.8 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.7 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 1.5 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 3.0 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 1.5 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 1.6 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.5 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.2 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 1.3 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.4 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 1.2 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.5 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.3 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.2 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.4 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.2 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.3 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling