Motif ID: Irf2_Irf1_Irf8_Irf9_Irf7

Z-value: 2.756


Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Irf1mm10_v2_chr11_+_53770458_537705090.511.5e-03Click!
Irf7mm10_v2_chr7_-_141266415_1412664810.492.3e-03Click!
Irf2mm10_v2_chr8_+_46739745_467397910.372.6e-02Click!
Irf8mm10_v2_chr8_+_120736352_120736385-0.344.4e-02Click!
Irf9mm10_v2_chr14_+_55604550_556045790.221.9e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Irf2_Irf1_Irf8_Irf9_Irf7

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_+_77729091 33.281 ENSMUST00000109775.2
Apol9b
apolipoprotein L 9b
chr1_+_130826676 19.845 ENSMUST00000027675.7
Pigr
polymeric immunoglobulin receptor
chr1_+_130826762 18.742 ENSMUST00000133792.1
Pigr
polymeric immunoglobulin receptor
chr15_-_77411034 17.580 ENSMUST00000089452.5
ENSMUST00000081776.3
Apol9a

apolipoprotein L 9a

chr2_-_173218879 16.475 ENSMUST00000109116.2
ENSMUST00000029018.7
Zbp1

Z-DNA binding protein 1

chr4_+_42629719 14.268 ENSMUST00000166898.2
Gm2564
predicted gene 2564
chr8_-_71537402 13.784 ENSMUST00000051672.7
Bst2
bone marrow stromal cell antigen 2
chr19_+_34607927 13.348 ENSMUST00000076249.5
I830012O16Rik
RIKEN cDNA I830012O16 gene
chr8_-_45333189 12.553 ENSMUST00000095328.4
Cyp4v3
cytochrome P450, family 4, subfamily v, polypeptide 3
chr19_+_34640871 12.192 ENSMUST00000102824.3
Ifit1
interferon-induced protein with tetratricopeptide repeats 1
chr18_+_60212080 12.063 ENSMUST00000031549.5
Gm4951
predicted gene 4951
chr2_+_122147680 11.551 ENSMUST00000102476.4
B2m
beta-2 microglobulin
chr19_-_11050500 11.534 ENSMUST00000099676.4
AW112010
expressed sequence AW112010
chr5_-_105239533 11.523 ENSMUST00000065588.6
Gbp10
guanylate-binding protein 10
chr11_+_70459940 10.964 ENSMUST00000147289.1
ENSMUST00000126105.1
Zmynd15

zinc finger, MYND-type containing 15

chr11_+_70459611 10.759 ENSMUST00000039093.3
Zmynd15
zinc finger, MYND-type containing 15
chr7_-_141010759 10.644 ENSMUST00000026565.6
Ifitm3
interferon induced transmembrane protein 3
chr11_+_49087022 10.496 ENSMUST00000046704.6
Ifi47
interferon gamma inducible protein 47
chr1_-_162984519 10.158 ENSMUST00000028010.7
Fmo3
flavin containing monooxygenase 3
chr3_-_151749877 9.575 ENSMUST00000029671.7
Ifi44
interferon-induced protein 44
chr19_+_34583528 9.532 ENSMUST00000102825.3
Ifit3
interferon-induced protein with tetratricopeptide repeats 3
chr16_+_43363855 9.379 ENSMUST00000156367.1
Zbtb20
zinc finger and BTB domain containing 20
chr10_+_40629987 9.222 ENSMUST00000019977.7
Ddo
D-aspartate oxidase
chr16_+_23609895 8.614 ENSMUST00000038423.5
Rtp4
receptor transporter protein 4
chr8_-_84773381 8.452 ENSMUST00000109764.1
Nfix
nuclear factor I/X
chr3_-_113574758 8.438 ENSMUST00000106540.1
Amy1
amylase 1, salivary
chr3_-_113574242 8.278 ENSMUST00000142505.2
Amy1
amylase 1, salivary
chr7_-_141266415 8.269 ENSMUST00000106023.1
ENSMUST00000097952.2
ENSMUST00000026571.4
Irf7


interferon regulatory factor 7


chr12_+_103434211 8.112 ENSMUST00000079294.5
ENSMUST00000076788.5
ENSMUST00000076702.5
ENSMUST00000066701.6
ENSMUST00000085065.5
ENSMUST00000140838.1
Ifi27





interferon, alpha-inducible protein 27





chr11_-_53859187 8.091 ENSMUST00000117316.1
ENSMUST00000120776.1
ENSMUST00000121435.1
Gm12216


predicted gene 12216


chr11_-_49064202 7.996 ENSMUST00000046745.6
Tgtp2
T cell specific GTPase 2
chr11_-_48992226 7.965 ENSMUST00000059930.2
ENSMUST00000068063.3
Gm12185
Tgtp1
predicted gene 12185
T cell specific GTPase 1
chr2_+_102706356 7.860 ENSMUST00000123759.1
ENSMUST00000111212.1
ENSMUST00000005220.4
Slc1a2


solute carrier family 1 (glial high affinity glutamate transporter), member 2


chr7_-_14446570 7.848 ENSMUST00000063509.4
2810007J24Rik
RIKEN cDNA 2810007J24 gene
chr15_-_77596110 7.767 ENSMUST00000089465.4
Apol10b
apolipoprotein L 10B
chr15_-_77533312 7.741 ENSMUST00000062562.5
Apol7c
apolipoprotein L 7c
chr9_+_20868628 7.640 ENSMUST00000043911.7
A230050P20Rik
RIKEN cDNA A230050P20 gene
chr7_-_14446651 7.577 ENSMUST00000125941.1
2810007J24Rik
RIKEN cDNA 2810007J24 gene
chr1_+_52119438 7.545 ENSMUST00000070968.7
Stat1
signal transducer and activator of transcription 1
chr17_-_36042690 7.440 ENSMUST00000058801.8
ENSMUST00000080015.5
ENSMUST00000077960.6
H2-T22


histocompatibility 2, T region locus 22


chr9_-_106476104 7.429 ENSMUST00000156426.1
Parp3
poly (ADP-ribose) polymerase family, member 3
chr9_-_106476372 7.399 ENSMUST00000123555.1
ENSMUST00000125850.1
Parp3

poly (ADP-ribose) polymerase family, member 3

chr17_-_34187219 7.357 ENSMUST00000173831.1
Psmb9
proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)
chr3_+_142620596 7.277 ENSMUST00000165774.1
Gbp2
guanylate binding protein 2
chr18_+_60376029 7.180 ENSMUST00000066912.5
ENSMUST00000032473.6
Iigp1

interferon inducible GTPase 1

chr9_-_106476590 7.146 ENSMUST00000112479.2
Parp3
poly (ADP-ribose) polymerase family, member 3
chr1_-_173599074 7.128 ENSMUST00000150649.1
ENSMUST00000180215.1
ENSMUST00000097462.2
Pydc4


pyrin domain containing 4


chr1_+_167618246 7.028 ENSMUST00000111380.1
Rxrg
retinoid X receptor gamma
chr4_-_42756543 6.881 ENSMUST00000102957.3
Ccl19
chemokine (C-C motif) ligand 19
chr9_+_77921908 6.453 ENSMUST00000133757.1
Elovl5
ELOVL family member 5, elongation of long chain fatty acids (yeast)
chr16_+_97536079 6.442 ENSMUST00000024112.7
Mx2
myxovirus (influenza virus) resistance 2
chr17_-_34862122 6.405 ENSMUST00000154526.1
Cfb
complement factor B
chr11_-_48871408 6.364 ENSMUST00000097271.2
Irgm1
immunity-related GTPase family M member 1
chr5_+_114923234 6.345 ENSMUST00000031540.4
ENSMUST00000112143.3
Oasl1

2'-5' oligoadenylate synthetase-like 1

chr6_-_23839137 6.323 ENSMUST00000166458.2
ENSMUST00000142913.2
ENSMUST00000115357.1
ENSMUST00000069074.7
ENSMUST00000115361.2
ENSMUST00000018122.7
ENSMUST00000115355.1
ENSMUST00000115356.2
Cadps2







Ca2+-dependent activator protein for secretion 2







chr11_-_48871344 6.296 ENSMUST00000049519.3
Irgm1
immunity-related GTPase family M member 1
chr6_-_39118211 6.219 ENSMUST00000038398.6
Parp12
poly (ADP-ribose) polymerase family, member 12
chr4_-_42773993 6.189 ENSMUST00000095114.4
Ccl21a
chemokine (C-C motif) ligand 21A (serine)
chr11_-_70459957 6.163 ENSMUST00000019064.2
Cxcl16
chemokine (C-X-C motif) ligand 16
chr1_+_175631996 6.004 ENSMUST00000040250.8
Kmo
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chrX_+_59999436 5.995 ENSMUST00000033477.4
F9
coagulation factor IX
chr11_+_72301613 5.994 ENSMUST00000151440.1
ENSMUST00000146233.1
ENSMUST00000140842.2
Xaf1


XIAP associated factor 1


chr1_-_150466165 5.988 ENSMUST00000162367.1
ENSMUST00000161611.1
ENSMUST00000161320.1
ENSMUST00000159035.1
Prg4



proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein)



chr11_+_119393060 5.941 ENSMUST00000131035.2
ENSMUST00000093902.5
Rnf213

ring finger protein 213

chr3_+_142560052 5.902 ENSMUST00000106222.2
Gbp3
guanylate binding protein 3
chr1_+_175632169 5.895 ENSMUST00000097458.3
Kmo
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr1_+_173673651 5.855 ENSMUST00000085876.4
Pydc3
pyrin domain containing 3
chr17_+_36121666 5.674 ENSMUST00000173128.1
Gm19684
predicted gene, 19684
chr4_+_42255767 5.656 ENSMUST00000178864.1
Ccl21b
chemokine (C-C motif) ligand 21B (leucine)
chr6_-_23839420 5.583 ENSMUST00000115358.2
ENSMUST00000163871.2
Cadps2

Ca2+-dependent activator protein for secretion 2

chr17_-_34862473 5.570 ENSMUST00000025229.4
ENSMUST00000176203.2
ENSMUST00000128767.1
Cfb


complement factor B


chr4_-_40239779 5.511 ENSMUST00000037907.6
Ddx58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr2_-_51972990 5.479 ENSMUST00000145481.1
ENSMUST00000112705.2
Nmi

N-myc (and STAT) interactor

chr3_+_142560351 5.438 ENSMUST00000106221.1
Gbp3
guanylate binding protein 3
chr5_-_105293699 5.411 ENSMUST00000050011.8
Gbp6
guanylate binding protein 6
chr3_+_142560108 5.408 ENSMUST00000128609.1
ENSMUST00000029935.7
Gbp3

guanylate binding protein 3

chr6_+_121245903 5.386 ENSMUST00000032198.9
Usp18
ubiquitin specific peptidase 18
chr7_+_51878967 5.336 ENSMUST00000051912.6
Gas2
growth arrest specific 2
chr17_+_34187545 5.306 ENSMUST00000170086.1
Tap1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr2_-_126933229 5.248 ENSMUST00000028844.4
Sppl2a
signal peptide peptidase like 2A
chr8_+_61928081 5.218 ENSMUST00000154398.1
ENSMUST00000093485.2
ENSMUST00000156980.1
ENSMUST00000070631.7
Ddx60



DEAD (Asp-Glu-Ala-Asp) box polypeptide 60



chr11_+_58199556 5.090 ENSMUST00000058704.8
ENSMUST00000035266.4
ENSMUST00000094169.4
ENSMUST00000168280.1
Irgm2
Igtp


immunity-related GTPase family M member 2
interferon gamma induced GTPase


chr17_+_34187789 5.089 ENSMUST00000041633.8
Tap1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr7_+_51879041 4.906 ENSMUST00000107591.2
Gas2
growth arrest specific 2
chr1_+_156035705 4.868 ENSMUST00000111754.2
ENSMUST00000133152.1
Tor1aip2

torsin A interacting protein 2

chr19_+_56397100 4.855 ENSMUST00000026062.9
Casp7
caspase 7
chr2_-_77170534 4.805 ENSMUST00000111833.2
Ccdc141
coiled-coil domain containing 141
chr11_-_100704217 4.759 ENSMUST00000017974.6
Dhx58
DEXH (Asp-Glu-X-His) box polypeptide 58
chr2_-_62646146 4.751 ENSMUST00000112459.3
ENSMUST00000028259.5
Ifih1

interferon induced with helicase C domain 1

chr16_+_43364145 4.729 ENSMUST00000148775.1
Zbtb20
zinc finger and BTB domain containing 20
chr6_+_128662379 4.610 ENSMUST00000032518.4
Clec2h
C-type lectin domain family 2, member h
chr3_+_60081861 4.603 ENSMUST00000029326.5
Sucnr1
succinate receptor 1
chr6_+_57580992 4.602 ENSMUST00000031817.8
Herc6
hect domain and RLD 6
chr4_+_41903610 4.578 ENSMUST00000098128.3
Gm21541
predicted gene, 21541
chr4_+_42114817 4.572 ENSMUST00000098123.3
Gm13304
predicted gene 13304
chr16_+_35938470 4.565 ENSMUST00000114878.1
Parp9
poly (ADP-ribose) polymerase family, member 9
chr15_+_99392882 4.558 ENSMUST00000023749.8
Tmbim6
transmembrane BAX inhibitor motif containing 6
chr15_-_76243401 4.522 ENSMUST00000165738.1
ENSMUST00000075689.6
Parp10

poly (ADP-ribose) polymerase family, member 10

chr7_+_119526269 4.506 ENSMUST00000066465.1
Acsm5
acyl-CoA synthetase medium-chain family member 5
chr6_-_85869128 4.452 ENSMUST00000045008.7
Cml2
camello-like 2
chr18_-_60273267 4.437 ENSMUST00000090260.4
Gm4841
predicted gene 4841
chr18_-_61536522 4.428 ENSMUST00000171629.1
Arhgef37
Rho guanine nucleotide exchange factor (GEF) 37
chr2_+_58755177 4.344 ENSMUST00000102755.3
Upp2
uridine phosphorylase 2
chr13_+_4434306 4.292 ENSMUST00000021630.8
Akr1c6
aldo-keto reductase family 1, member C6
chr17_-_34000257 4.289 ENSMUST00000087189.6
ENSMUST00000173075.1
ENSMUST00000172760.1
ENSMUST00000172912.1
ENSMUST00000025181.10
H2-K1




histocompatibility 2, K1, K region




chr13_+_4059565 4.258 ENSMUST00000041768.6
Akr1c14
aldo-keto reductase family 1, member C14
chr16_-_24393588 4.208 ENSMUST00000181640.1
1110054M08Rik
RIKEN cDNA 1110054M08 gene
chr2_+_58754910 4.206 ENSMUST00000059102.6
Upp2
uridine phosphorylase 2
chr16_+_35938972 4.186 ENSMUST00000023622.6
ENSMUST00000114877.1
Parp9

poly (ADP-ribose) polymerase family, member 9

chr3_+_142594847 4.101 ENSMUST00000029936.4
Gbp2b
guanylate binding protein 2b
chr11_-_78984946 4.092 ENSMUST00000108268.3
Lgals9
lectin, galactose binding, soluble 9
chr3_-_98630309 4.023 ENSMUST00000044094.4
Hsd3b5
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5
chr5_-_92348871 4.006 ENSMUST00000038816.6
ENSMUST00000118006.1
Cxcl10

chemokine (C-X-C motif) ligand 10

chr17_+_33919332 3.994 ENSMUST00000025161.7
Tapbp
TAP binding protein
chr9_+_5345450 3.960 ENSMUST00000151332.1
Casp12
caspase 12
chr1_-_153851189 3.943 ENSMUST00000059607.6
5830403L16Rik
RIKEN cDNA 5830403L16 gene
chr4_-_46536096 3.940 ENSMUST00000102924.2
Trim14
tripartite motif-containing 14
chr4_-_46536134 3.912 ENSMUST00000046897.6
Trim14
tripartite motif-containing 14
chr1_-_173490933 3.900 ENSMUST00000160565.2
Gm4955
predicted gene 4955
chr9_+_5345414 3.879 ENSMUST00000027009.4
Casp12
caspase 12
chr11_+_58215028 3.871 ENSMUST00000108836.1
Irgm2
immunity-related GTPase family M member 2
chr8_-_105938384 3.844 ENSMUST00000034369.8
Psmb10
proteasome (prosome, macropain) subunit, beta type 10
chr8_-_93279717 3.820 ENSMUST00000034178.8
Ces1f
carboxylesterase 1F
chr14_-_7994563 3.813 ENSMUST00000026315.7
Dnase1l3
deoxyribonuclease 1-like 3
chr18_-_3299537 3.751 ENSMUST00000129435.1
ENSMUST00000122958.1
Crem

cAMP responsive element modulator

chr10_-_34127955 3.687 ENSMUST00000062784.6
Fam26f
family with sequence similarity 26, member F
chr1_+_13668739 3.663 ENSMUST00000088542.3
Xkr9
X Kell blood group precursor related family member 9 homolog
chr17_+_37193889 3.642 ENSMUST00000038844.6
Ubd
ubiquitin D
chr2_+_72054598 3.583 ENSMUST00000028525.5
Rapgef4
Rap guanine nucleotide exchange factor (GEF) 4
chr6_-_31218421 3.577 ENSMUST00000115107.1
AB041803
cDNA sequence AB041803
chr11_-_78984831 3.502 ENSMUST00000073001.4
ENSMUST00000108269.3
Lgals9

lectin, galactose binding, soluble 9

chr6_-_125231772 3.478 ENSMUST00000043422.7
Tapbpl
TAP binding protein-like
chr13_-_23710714 3.459 ENSMUST00000091707.6
ENSMUST00000006787.7
ENSMUST00000091706.6
Hfe


hemochromatosis


chr1_-_172590463 3.443 ENSMUST00000065679.6
Slamf8
SLAM family member 8
chr6_+_34745952 3.411 ENSMUST00000123823.1
ENSMUST00000136907.1
ENSMUST00000126181.1
Cald1


caldesmon 1


chr2_+_68117713 3.395 ENSMUST00000112346.2
B3galt1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr2_-_24049389 3.383 ENSMUST00000051416.5
Hnmt
histamine N-methyltransferase
chr7_+_104244449 3.381 ENSMUST00000106849.2
ENSMUST00000060315.5
Trim34a

tripartite motif-containing 34A

chr17_+_35439155 3.371 ENSMUST00000071951.6
ENSMUST00000078205.7
ENSMUST00000116598.3
ENSMUST00000076256.7
H2-Q7



histocompatibility 2, Q region locus 7



chr5_+_67260794 3.290 ENSMUST00000161369.1
Tmem33
transmembrane protein 33
chr8_+_70083509 3.238 ENSMUST00000007738.9
Hapln4
hyaluronan and proteoglycan link protein 4
chr1_+_156035392 3.214 ENSMUST00000111757.3
Tor1aip2
torsin A interacting protein 2
chr7_+_104244465 3.211 ENSMUST00000106848.1
Trim34a
tripartite motif-containing 34A
chr2_-_51973219 3.190 ENSMUST00000028314.2
Nmi
N-myc (and STAT) interactor
chr15_+_75862310 3.184 ENSMUST00000023238.4
Gsdmd
gasdermin D
chr16_-_35939082 3.184 ENSMUST00000081933.7
ENSMUST00000114885.1
Dtx3l

deltex 3-like (Drosophila)

chr13_+_51846673 3.113 ENSMUST00000021903.2
Gadd45g
growth arrest and DNA-damage-inducible 45 gamma
chr7_+_107567445 3.109 ENSMUST00000120990.1
Olfml1
olfactomedin-like 1
chr7_+_104244496 3.047 ENSMUST00000106854.1
ENSMUST00000143414.1
Trim34a

tripartite motif-containing 34A

chr3_+_27317028 2.963 ENSMUST00000046383.5
ENSMUST00000174840.1
Tnfsf10

tumor necrosis factor (ligand) superfamily, member 10

chr3_+_142530329 2.937 ENSMUST00000171263.1
ENSMUST00000045097.9
Gbp7

guanylate binding protein 7

chr15_-_76014318 2.915 ENSMUST00000060807.5
Fam83h
family with sequence similarity 83, member H
chr6_+_124512615 2.898 ENSMUST00000068593.7
C1ra
complement component 1, r subcomponent A
chr13_+_33004528 2.895 ENSMUST00000006391.4
Serpinb9
serine (or cysteine) peptidase inhibitor, clade B, member 9
chr3_+_81932601 2.829 ENSMUST00000029649.2
Ctso
cathepsin O
chr4_+_135728116 2.829 ENSMUST00000102546.3
Il22ra1
interleukin 22 receptor, alpha 1
chr5_-_105139539 2.812 ENSMUST00000100961.4
ENSMUST00000031235.6
ENSMUST00000100962.3
Gbp9
Gbp8
Gbp4
guanylate-binding protein 9
guanylate-binding protein 8
guanylate binding protein 4
chr18_-_3299452 2.812 ENSMUST00000126578.1
Crem
cAMP responsive element modulator
chr1_-_155146755 2.801 ENSMUST00000027744.8
Mr1
major histocompatibility complex, class I-related
chr13_+_74639866 2.757 ENSMUST00000169114.1
Erap1
endoplasmic reticulum aminopeptidase 1
chr12_+_37241633 2.748 ENSMUST00000049874.7
Agmo
alkylglycerol monooxygenase
chr5_-_105110292 2.738 ENSMUST00000031238.6
Gbp9
guanylate-binding protein 9
chr2_+_43555321 2.702 ENSMUST00000028223.2
Kynu
kynureninase (L-kynurenine hydrolase)
chr4_-_40239700 2.694 ENSMUST00000142055.1
Ddx58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr6_-_38354243 2.680 ENSMUST00000114900.1
Zc3hav1
zinc finger CCCH type, antiviral 1
chr19_-_7966000 2.677 ENSMUST00000182102.1
ENSMUST00000075619.4
Slc22a27

solute carrier family 22, member 27

chr12_+_37241729 2.667 ENSMUST00000160768.1
Agmo
alkylglycerol monooxygenase
chr18_+_60293372 2.663 ENSMUST00000171297.1
F830016B08Rik
RIKEN cDNA F830016B08 gene
chr15_-_76307101 2.657 ENSMUST00000171340.1
Oplah
5-oxoprolinase (ATP-hydrolysing)
chr5_-_91402905 2.640 ENSMUST00000121044.2
Btc
betacellulin, epidermal growth factor family member
chr3_-_86999284 2.638 ENSMUST00000063869.5
ENSMUST00000029717.2
Cd1d1

CD1d1 antigen

chr16_+_26581704 2.633 ENSMUST00000096129.2
ENSMUST00000166294.2
ENSMUST00000174202.1
ENSMUST00000023156.6
Il1rap



interleukin 1 receptor accessory protein



chr3_+_142496924 2.614 ENSMUST00000090127.2
Gbp5
guanylate binding protein 5
chr9_-_50555170 2.603 ENSMUST00000119103.1
Bco2
beta-carotene oxygenase 2
chr10_+_39612934 2.592 ENSMUST00000019987.6
Traf3ip2
TRAF3 interacting protein 2
chr8_-_3748941 2.584 ENSMUST00000012847.1
Cd209a
CD209a antigen
chr2_+_43555342 2.568 ENSMUST00000112826.1
ENSMUST00000050511.6
Kynu

kynureninase (L-kynurenine hydrolase)

chr1_+_130865669 2.567 ENSMUST00000038829.5
Faim3
Fas apoptotic inhibitory molecule 3
chr2_-_126783416 2.566 ENSMUST00000130356.1
ENSMUST00000028842.2
Usp50

ubiquitin specific peptidase 50

chr2_+_27676440 2.554 ENSMUST00000129514.1
Rxra
retinoid X receptor alpha
chr17_+_35262730 2.553 ENSMUST00000172785.1
H2-D1
histocompatibility 2, D region locus 1
chr17_+_35470083 2.515 ENSMUST00000174525.1
ENSMUST00000068291.6
H2-Q10

histocompatibility 2, Q region locus 10

chr12_+_37242030 2.504 ENSMUST00000160390.1
Agmo
alkylglycerol monooxygenase
chr6_-_54972603 2.495 ENSMUST00000060655.8
Nod1
nucleotide-binding oligomerization domain containing 1
chr8_-_111338152 2.465 ENSMUST00000056157.7
ENSMUST00000120432.1
Mlkl

mixed lineage kinase domain-like

chr14_+_41105359 2.459 ENSMUST00000047286.6
Mat1a
methionine adenosyltransferase I, alpha
chr10_-_92375367 2.401 ENSMUST00000182870.1
Gm20757
predicted gene, 20757
chr19_+_8898090 2.392 ENSMUST00000096246.3
Ganab
alpha glucosidase 2 alpha neutral subunit
chr17_+_31433054 2.372 ENSMUST00000136384.1
Pde9a
phosphodiesterase 9A
chr8_-_3878549 2.362 ENSMUST00000011445.6
Cd209d
CD209d antigen
chr10_+_128270546 2.344 ENSMUST00000105238.3
ENSMUST00000085708.2
Stat2

signal transducer and activator of transcription 2

chr8_-_84800024 2.341 ENSMUST00000126806.1
ENSMUST00000076715.6
Nfix

nuclear factor I/X

chr19_-_24861828 2.336 ENSMUST00000047666.4
Pgm5
phosphoglucomutase 5
chr8_-_84800344 2.325 ENSMUST00000099070.3
Nfix
nuclear factor I/X
chr4_+_155582476 2.324 ENSMUST00000105612.1
Nadk
NAD kinase
chr2_-_77170592 2.323 ENSMUST00000164114.2
ENSMUST00000049544.7
Ccdc141

coiled-coil domain containing 141

chr3_+_138313279 2.299 ENSMUST00000013455.6
ENSMUST00000106247.1
Adh6a

alcohol dehydrogenase 6A (class V)

chr10_+_4611971 2.288 ENSMUST00000105590.1
ENSMUST00000067086.7
Esr1

estrogen receptor 1 (alpha)

chr19_-_21472552 2.283 ENSMUST00000087600.3
Gda
guanine deaminase
chr2_+_19371636 2.277 ENSMUST00000023856.8
Msrb2
methionine sulfoxide reductase B2

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
9.6 38.6 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
7.3 22.0 GO:1990166 protein localization to site of double-strand break(GO:1990166)
4.4 13.1 GO:2000547 regulation of dendritic cell dendrite assembly(GO:2000547)
3.5 3.5 GO:0002589 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589)
3.5 41.6 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
3.3 10.0 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
3.1 176.4 GO:0035456 response to interferon-beta(GO:0035456)
3.1 9.2 GO:0006533 aspartate catabolic process(GO:0006533)
2.9 8.7 GO:1902524 positive regulation of protein K48-linked ubiquitination(GO:1902524)
2.9 17.2 GO:0019805 quinolinate biosynthetic process(GO:0019805)
2.8 8.3 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
2.1 2.1 GO:1904933 regulation of cell proliferation in midbrain(GO:1904933)
2.0 12.2 GO:0035547 interferon-beta secretion(GO:0035546) regulation of interferon-beta secretion(GO:0035547) positive regulation of interferon-beta secretion(GO:0035549)
2.0 10.0 GO:1904721 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
1.9 17.1 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
1.8 9.0 GO:2000562 negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
1.6 4.9 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
1.6 6.4 GO:1903896 positive regulation of IRE1-mediated unfolded protein response(GO:1903896)
1.5 4.5 GO:1902915 negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
1.5 1.5 GO:0002489 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489)
1.4 4.3 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
1.3 5.3 GO:1901740 negative regulation of myoblast fusion(GO:1901740)
1.3 3.8 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
1.1 3.4 GO:0019883 antigen processing and presentation of endogenous antigen(GO:0019883)
1.1 7.9 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
1.0 2.9 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.9 3.6 GO:1904457 positive regulation of neuronal action potential(GO:1904457)
0.9 3.5 GO:0002606 positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.9 70.7 GO:0034341 response to interferon-gamma(GO:0034341)
0.9 11.9 GO:1990504 dense core granule exocytosis(GO:1990504)
0.8 2.5 GO:0018900 dichloromethane metabolic process(GO:0018900)
0.8 13.2 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.8 14.5 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.8 2.3 GO:0046098 guanine metabolic process(GO:0046098)
0.7 6.0 GO:0045409 negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.7 8.1 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.7 4.4 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.7 9.5 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.7 3.4 GO:1902623 leukocyte chemotaxis involved in inflammatory response(GO:0002232) negative regulation of neutrophil migration(GO:1902623)
0.7 2.0 GO:0071211 protein targeting to vacuole involved in autophagy(GO:0071211)
0.7 2.6 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.7 5.2 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.7 2.0 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302) mesodermal to mesenchymal transition involved in gastrulation(GO:0060809)
0.6 8.0 GO:0097264 self proteolysis(GO:0097264)
0.6 2.5 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.6 1.8 GO:0038129 ERBB3 signaling pathway(GO:0038129) regulation of protein localization to endoplasmic reticulum(GO:1905550) positive regulation of protein localization to endoplasmic reticulum(GO:1905552)
0.6 1.8 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.6 1.1 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.6 1.7 GO:1903538 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.6 1.7 GO:0002014 vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure(GO:0002014)
0.5 1.6 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.5 6.5 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.5 2.1 GO:0046351 disaccharide biosynthetic process(GO:0046351)
0.5 1.0 GO:0006714 sesquiterpenoid metabolic process(GO:0006714)
0.5 2.1 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.5 2.6 GO:0006447 regulation of translational initiation by iron(GO:0006447) positive regulation of translational initiation by iron(GO:0045994)
0.5 8.0 GO:0046485 ether lipid metabolic process(GO:0046485)
0.5 1.5 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.5 3.4 GO:0052805 imidazole-containing compound catabolic process(GO:0052805)
0.5 9.0 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.5 1.4 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.4 0.4 GO:1990009 retinal cell apoptotic process(GO:1990009)
0.4 17.7 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.4 3.5 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.4 2.2 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.4 2.2 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.4 2.5 GO:0003383 apical constriction(GO:0003383)
0.4 11.5 GO:0035634 response to stilbenoid(GO:0035634)
0.4 1.2 GO:0032474 otolith morphogenesis(GO:0032474) otolith development(GO:0048840)
0.4 0.8 GO:0071649 regulation of chemokine (C-C motif) ligand 5 production(GO:0071649)
0.4 2.3 GO:0006741 NADP biosynthetic process(GO:0006741)
0.4 0.8 GO:0071332 cellular response to fructose stimulus(GO:0071332)
0.4 1.1 GO:0048239 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.4 12.2 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.4 2.3 GO:0060011 Sertoli cell proliferation(GO:0060011) prostate epithelial cord elongation(GO:0060523) epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750) branch elongation involved in mammary gland duct branching(GO:0060751)
0.4 1.5 GO:0010901 negative regulation of cytokine secretion involved in immune response(GO:0002740) regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
0.4 1.5 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.4 3.8 GO:0042095 interferon-gamma biosynthetic process(GO:0042095)
0.4 10.2 GO:0017144 drug metabolic process(GO:0017144)
0.4 1.1 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.4 0.7 GO:0097527 necroptotic signaling pathway(GO:0097527)
0.4 0.7 GO:0035928 rRNA import into mitochondrion(GO:0035928)
0.3 1.0 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.3 1.4 GO:1901373 lipid hydroperoxide transport(GO:1901373)
0.3 1.7 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.3 1.0 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.3 7.9 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.3 2.6 GO:0008300 isoprenoid catabolic process(GO:0008300)
0.3 2.3 GO:0030091 protein repair(GO:0030091)
0.3 0.9 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.3 2.8 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.3 1.8 GO:0044375 regulation of peroxisome size(GO:0044375)
0.3 0.9 GO:0002223 stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.3 2.1 GO:0072086 specification of loop of Henle identity(GO:0072086)
0.3 2.0 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.3 1.4 GO:0070494 regulation of thrombin-activated receptor signaling pathway(GO:0070494) negative regulation of thrombin-activated receptor signaling pathway(GO:0070495)
0.3 1.1 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.3 0.5 GO:0038091 VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091)
0.3 1.6 GO:0051204 protein insertion into mitochondrial membrane(GO:0051204)
0.3 1.3 GO:0045351 type I interferon biosynthetic process(GO:0045351)
0.3 0.5 GO:0099082 retrograde trans-synaptic signaling by neuropeptide(GO:0099082)
0.3 1.6 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.3 2.6 GO:0035810 positive regulation of urine volume(GO:0035810)
0.3 1.6 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.3 0.8 GO:1905051 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.3 3.8 GO:0010623 programmed cell death involved in cell development(GO:0010623)
0.3 13.2 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.3 1.8 GO:0010991 regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991)
0.2 2.2 GO:0071357 type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.2 2.2 GO:0032494 response to peptidoglycan(GO:0032494)
0.2 1.0 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.2 0.7 GO:0006553 lysine metabolic process(GO:0006553)
0.2 1.7 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.2 1.2 GO:0019348 dolichol metabolic process(GO:0019348)
0.2 0.7 GO:0061076 camera-type eye photoreceptor cell fate commitment(GO:0060220) negative regulation of neural retina development(GO:0061076) negative regulation of retina development in camera-type eye(GO:1902867) negative regulation of amacrine cell differentiation(GO:1902870)
0.2 0.2 GO:0018307 enzyme active site formation(GO:0018307)
0.2 0.7 GO:0097343 ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.2 1.4 GO:0036112 medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
0.2 2.9 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.2 0.2 GO:2000793 cell proliferation involved in heart valve development(GO:2000793)
0.2 7.0 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.2 0.4 GO:0071316 cellular response to nicotine(GO:0071316)
0.2 1.2 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.2 0.8 GO:1905355 spine apparatus assembly(GO:1905355)
0.2 1.2 GO:0015889 cobalamin transport(GO:0015889)
0.2 0.4 GO:1905169 protein localization to phagocytic vesicle(GO:1905161) regulation of protein localization to phagocytic vesicle(GO:1905169) positive regulation of protein localization to phagocytic vesicle(GO:1905171)
0.2 1.5 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.2 0.2 GO:2000911 positive regulation of cholesterol import(GO:1904109) positive regulation of sterol import(GO:2000911)
0.2 0.9 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.2 1.7 GO:0071763 nuclear membrane organization(GO:0071763)
0.2 1.8 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
0.2 1.4 GO:0097475 motor neuron migration(GO:0097475)
0.2 1.8 GO:0003374 dynamin family protein polymerization involved in membrane fission(GO:0003373) dynamin family protein polymerization involved in mitochondrial fission(GO:0003374)
0.2 1.1 GO:0033227 dsRNA transport(GO:0033227)
0.2 0.5 GO:0045348 positive regulation of MHC class II biosynthetic process(GO:0045348)
0.2 0.7 GO:0006624 vacuolar protein processing(GO:0006624)
0.2 0.9 GO:0010992 ubiquitin recycling(GO:0010992)
0.2 0.7 GO:0034769 basement membrane disassembly(GO:0034769)
0.2 0.7 GO:0043328 protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.2 1.8 GO:0014807 regulation of somitogenesis(GO:0014807)
0.2 0.8 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.2 3.0 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.2 2.5 GO:2000778 positive regulation of interleukin-6 secretion(GO:2000778)
0.2 0.3 GO:0048687 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
0.2 0.5 GO:0006404 RNA import into nucleus(GO:0006404) snRNA transport(GO:0051030)
0.2 7.8 GO:0019882 antigen processing and presentation(GO:0019882)
0.2 0.5 GO:1905666 regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966) regulation of protein localization to endosome(GO:1905666) positive regulation of protein localization to endosome(GO:1905668)
0.2 2.4 GO:0033327 Leydig cell differentiation(GO:0033327)
0.2 0.5 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.2 0.5 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.2 0.6 GO:0019853 L-ascorbic acid biosynthetic process(GO:0019853)
0.2 0.8 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.2 2.1 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.1 1.9 GO:0032836 glomerular basement membrane development(GO:0032836)
0.1 1.5 GO:0021678 third ventricle development(GO:0021678)
0.1 0.9 GO:1901317 regulation of flagellated sperm motility(GO:1901317)
0.1 0.6 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.1 1.5 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 1.2 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 2.4 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.1 5.5 GO:0051642 centrosome localization(GO:0051642)
0.1 1.1 GO:0035902 response to immobilization stress(GO:0035902)
0.1 1.9 GO:0019321 pentose metabolic process(GO:0019321)
0.1 0.4 GO:0015828 tyrosine transport(GO:0015828)
0.1 0.3 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.1 4.6 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 1.1 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.1 0.4 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931) calcium-independent cell-matrix adhesion(GO:0007161) cellular response to mercury ion(GO:0071288)
0.1 2.4 GO:0006491 N-glycan processing(GO:0006491)
0.1 1.3 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 1.6 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.1 0.4 GO:0003360 brainstem development(GO:0003360)
0.1 1.9 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.1 3.0 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.1 1.2 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 0.1 GO:1903719 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.1 1.0 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.1 15.3 GO:0019395 fatty acid oxidation(GO:0019395)
0.1 0.5 GO:1900020 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.1 2.6 GO:0061462 protein localization to lysosome(GO:0061462)
0.1 1.5 GO:0009143 nucleoside triphosphate catabolic process(GO:0009143)
0.1 0.8 GO:0060613 fat pad development(GO:0060613)
0.1 2.2 GO:0046931 pore complex assembly(GO:0046931)
0.1 4.3 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.1 1.4 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.1 4.4 GO:0070207 protein homotrimerization(GO:0070207)
0.1 19.0 GO:0007286 spermatid development(GO:0007286)
0.1 1.0 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.1 0.8 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.1 0.3 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.1 1.2 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.1 0.4 GO:0038095 Fc-epsilon receptor signaling pathway(GO:0038095)
0.1 0.7 GO:0039019 pronephric nephron development(GO:0039019)
0.1 0.3 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.1 1.5 GO:0015747 urate transport(GO:0015747)
0.1 0.7 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.5 GO:0002115 store-operated calcium entry(GO:0002115)
0.1 0.7 GO:0016266 O-glycan processing(GO:0016266)
0.1 1.3 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.1 0.7 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.1 0.4 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 1.7 GO:0008053 mitochondrial fusion(GO:0008053)
0.1 0.8 GO:0048245 mast cell chemotaxis(GO:0002551) eosinophil chemotaxis(GO:0048245)
0.1 0.8 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.1 0.7 GO:0045901 positive regulation of translational elongation(GO:0045901)
0.1 0.5 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.1 0.5 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.1 0.5 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 0.8 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.1 1.2 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.1 0.5 GO:0060763 mammary duct terminal end bud growth(GO:0060763)
0.1 0.5 GO:0060278 regulation of ovulation(GO:0060278)
0.1 0.4 GO:0000023 maltose metabolic process(GO:0000023)
0.1 0.8 GO:0034116 positive regulation of heterotypic cell-cell adhesion(GO:0034116)
0.1 1.0 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.1 0.6 GO:0006983 ER overload response(GO:0006983)
0.1 1.1 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.3 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.1 10.8 GO:0016052 carbohydrate catabolic process(GO:0016052)
0.1 2.1 GO:0019433 triglyceride catabolic process(GO:0019433)
0.1 1.4 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 0.6 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.1 0.4 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.1 1.9 GO:1903513 retrograde protein transport, ER to cytosol(GO:0030970) endoplasmic reticulum to cytosol transport(GO:1903513)
0.1 0.4 GO:0090168 Golgi reassembly(GO:0090168)
0.1 1.7 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 0.2 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.1 0.4 GO:0002121 inter-male aggressive behavior(GO:0002121)
0.1 0.3 GO:0071898 regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
0.1 0.4 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.1 0.5 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 0.7 GO:0007343 egg activation(GO:0007343)
0.1 0.4 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 0.2 GO:0106004 tRNA (guanine-N7)-methylation(GO:0106004)
0.1 0.2 GO:0021852 pyramidal neuron migration(GO:0021852)
0.1 0.5 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.1 1.0 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.1 1.3 GO:0051923 sulfation(GO:0051923)
0.1 0.6 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.1 0.9 GO:0072311 renal filtration cell differentiation(GO:0061318) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.1 0.2 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.1 0.6 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.1 1.2 GO:0072189 ureter development(GO:0072189)
0.1 0.7 GO:0006047 UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.1 2.8 GO:0044380 protein localization to cytoskeleton(GO:0044380)
0.1 3.0 GO:1902653 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.1 4.5 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.1 0.9 GO:0008298 intracellular mRNA localization(GO:0008298)
0.1 0.7 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.1 0.4 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.1 0.7 GO:1990403 embryonic brain development(GO:1990403)
0.1 0.4 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.1 0.6 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.1 0.9 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.1 1.0 GO:0032689 negative regulation of interferon-gamma production(GO:0032689)
0.1 2.4 GO:0010390 histone monoubiquitination(GO:0010390)
0.1 1.6 GO:1902857 positive regulation of non-motile cilium assembly(GO:1902857)
0.1 0.1 GO:0060025 regulation of synaptic activity(GO:0060025)
0.1 0.7 GO:1902170 cellular response to reactive nitrogen species(GO:1902170)
0.1 2.2 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.1 0.8 GO:0043248 proteasome assembly(GO:0043248)
0.1 0.1 GO:0042339 keratan sulfate metabolic process(GO:0042339)
0.1 0.1 GO:0000960 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960) mitochondrial RNA 3'-end processing(GO:0000965)
0.1 0.2 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.1 0.5 GO:0002755 MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.1 0.4 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.1 0.2 GO:2000383 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.0 0.4 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.0 0.3 GO:0048852 diencephalon morphogenesis(GO:0048852)
0.0 0.5 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.9 GO:0031167 rRNA methylation(GO:0031167)
0.0 0.3 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
0.0 0.9 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.9 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.0 1.1 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.3 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.0 0.1 GO:0097576 vacuole fusion(GO:0097576)
0.0 0.5 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.4 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.8 GO:0002360 T cell lineage commitment(GO:0002360)
0.0 0.2 GO:2000293 regulation of eating behavior(GO:1903998) negative regulation of eating behavior(GO:1903999) regulation of defecation(GO:2000292) negative regulation of defecation(GO:2000293)
0.0 1.1 GO:0007635 chemosensory behavior(GO:0007635)
0.0 0.6 GO:0009062 fatty acid catabolic process(GO:0009062)
0.0 5.1 GO:0009116 nucleoside metabolic process(GO:0009116)
0.0 0.2 GO:1900364 negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364)
0.0 0.3 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 3.0 GO:0030193 regulation of blood coagulation(GO:0030193) regulation of hemostasis(GO:1900046)
0.0 0.4 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 1.0 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.2 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 5.8 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.1 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.0 0.5 GO:0032526 response to retinoic acid(GO:0032526)
0.0 0.7 GO:0006450 regulation of translational fidelity(GO:0006450)
0.0 3.4 GO:0032092 positive regulation of protein binding(GO:0032092)
0.0 0.3 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.0 1.0 GO:0006767 water-soluble vitamin metabolic process(GO:0006767)
0.0 0.4 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.3 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 0.3 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 2.0 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.5 GO:1903543 regulation of exosomal secretion(GO:1903541) positive regulation of exosomal secretion(GO:1903543)
0.0 0.1 GO:0050906 detection of stimulus involved in sensory perception(GO:0050906)
0.0 0.6 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.8 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.9 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.7 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 1.1 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.8 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.1 GO:0021623 oculomotor nerve morphogenesis(GO:0021622) oculomotor nerve formation(GO:0021623)
0.0 0.6 GO:0007143 female meiotic nuclear division(GO:0007143)
0.0 0.0 GO:0046881 positive regulation of follicle-stimulating hormone secretion(GO:0046881)
0.0 0.4 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 1.9 GO:0006006 glucose metabolic process(GO:0006006)
0.0 1.1 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.0 0.2 GO:0009214 cyclic nucleotide catabolic process(GO:0009214)
0.0 0.2 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.2 GO:0010452 histone H3-K36 methylation(GO:0010452)
0.0 0.1 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.0 0.3 GO:0006857 oligopeptide transport(GO:0006857)
0.0 0.0 GO:0090365 regulation of mRNA modification(GO:0090365)
0.0 0.2 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.2 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0 0.1 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.0 0.9 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.1 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.0 0.2 GO:0045779 negative regulation of bone resorption(GO:0045779)
0.0 0.8 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.9 GO:0046825 regulation of protein export from nucleus(GO:0046825)
0.0 0.1 GO:0051096 regulation of helicase activity(GO:0051095) positive regulation of helicase activity(GO:0051096)
0.0 0.7 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.2 GO:2000650 negative regulation of sodium ion transmembrane transport(GO:1902306) negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.0 0.6 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)
0.0 0.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 1.0 GO:0006360 transcription from RNA polymerase I promoter(GO:0006360)
0.0 0.1 GO:0002154 thyroid hormone mediated signaling pathway(GO:0002154) regulation of thyroid hormone mediated signaling pathway(GO:0002155)
0.0 0.2 GO:0046337 phosphatidylethanolamine metabolic process(GO:0046337)
0.0 0.2 GO:0007281 germ cell development(GO:0007281)
0.0 1.1 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.3 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.5 GO:0030433 ubiquitin-dependent ERAD pathway(GO:0030433)
0.0 0.2 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 0.2 GO:0008542 visual learning(GO:0008542)
0.0 0.0 GO:0006583 melanin biosynthetic process from tyrosine(GO:0006583)
0.0 0.6 GO:0009060 aerobic respiration(GO:0009060)
0.0 0.2 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.1 GO:0001843 neural tube closure(GO:0001843)
0.0 0.3 GO:0009072 aromatic amino acid family metabolic process(GO:0009072)
0.0 0.1 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.0 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0 0.1 GO:0032534 phosphatidic acid biosynthetic process(GO:0006654) regulation of microvillus assembly(GO:0032534)
0.0 0.1 GO:0090272 negative regulation of fibroblast growth factor production(GO:0090272)
0.0 0.3 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.0 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.0 0.0 GO:0060744 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.0 0.1 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.1 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.0 0.3 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.0 0.4 GO:0071300 cellular response to retinoic acid(GO:0071300)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
4.2 58.2 GO:0020003 symbiont-containing vacuole(GO:0020003)
2.7 32.3 GO:0042612 MHC class I protein complex(GO:0042612)
2.2 11.2 GO:1990111 spermatoproteasome complex(GO:1990111)
2.1 17.0 GO:0042825 TAP complex(GO:0042825)
1.6 6.5 GO:0097447 dendritic tree(GO:0097447)
1.1 8.6 GO:0045098 type III intermediate filament(GO:0045098)
0.9 14.1 GO:0044754 autolysosome(GO:0044754)
0.9 38.6 GO:0055038 recycling endosome membrane(GO:0055038)
0.9 5.2 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.9 7.8 GO:0030478 actin cap(GO:0030478)
0.7 3.6 GO:0044316 cone cell pedicle(GO:0044316)
0.6 1.1 GO:0030870 Mre11 complex(GO:0030870)
0.5 2.3 GO:0005914 spot adherens junction(GO:0005914)
0.4 2.6 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.4 3.5 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.4 6.0 GO:0043657 host(GO:0018995) host cell(GO:0043657)
0.4 1.2 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.4 17.0 GO:0090734 site of double-strand break(GO:0035861) site of DNA damage(GO:0090734)
0.4 1.9 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.3 2.3 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.3 1.9 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.3 2.5 GO:0033269 internode region of axon(GO:0033269)
0.3 2.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.3 2.2 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.3 1.5 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.3 3.0 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.3 1.2 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.3 1.2 GO:0099053 activating signal cointegrator 1 complex(GO:0099053)
0.3 1.5 GO:0071986 Ragulator complex(GO:0071986)
0.3 0.8 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.3 1.0 GO:0043202 lysosomal lumen(GO:0043202)
0.2 2.4 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.2 23.0 GO:0042734 presynaptic membrane(GO:0042734)
0.2 0.7 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.2 0.7 GO:0000814 ESCRT II complex(GO:0000814)
0.2 0.9 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.2 6.8 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.2 0.8 GO:0097444 spine apparatus(GO:0097444)
0.2 1.2 GO:0045293 mRNA editing complex(GO:0045293)
0.2 1.4 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.2 2.4 GO:0042611 MHC protein complex(GO:0042611)
0.2 2.1 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.2 1.0 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.2 0.9 GO:0072487 MSL complex(GO:0072487)
0.2 0.8 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.2 1.2 GO:0070695 FHF complex(GO:0070695)
0.1 6.5 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 0.4 GO:0043512 inhibin A complex(GO:0043512)
0.1 1.2 GO:0005839 proteasome core complex(GO:0005839)
0.1 1.7 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 3.2 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 2.4 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.1 1.6 GO:1990635 proximal dendrite(GO:1990635)
0.1 0.4 GO:0044307 dendritic branch(GO:0044307)
0.1 1.2 GO:0005579 membrane attack complex(GO:0005579)
0.1 16.6 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.1 1.4 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.1 50.3 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.1 17.1 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 0.6 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189)
0.1 0.4 GO:0097059 ciliary neurotrophic factor receptor complex(GO:0070110) CNTFR-CLCF1 complex(GO:0097059)
0.1 3.0 GO:0045095 keratin filament(GO:0045095)
0.1 0.4 GO:0002111 BRCA2-BRAF35 complex(GO:0002111)
0.1 1.6 GO:0031527 filopodium membrane(GO:0031527)
0.1 0.3 GO:0071942 XPC complex(GO:0071942)
0.1 1.8 GO:0005922 connexin complex(GO:0005922)
0.1 0.5 GO:0051286 cell tip(GO:0051286)
0.1 0.2 GO:1990462 omegasome(GO:1990462)
0.1 0.4 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.1 5.5 GO:0005811 lipid droplet(GO:0005811)
0.1 10.6 GO:0072562 blood microparticle(GO:0072562)
0.1 1.2 GO:0071819 SAGA complex(GO:0000124) DUBm complex(GO:0071819)
0.1 3.2 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 8.6 GO:0005667 transcription factor complex(GO:0005667)
0.1 1.0 GO:0017119 Golgi transport complex(GO:0017119)
0.1 0.7 GO:0005675 holo TFIIH complex(GO:0005675)
0.1 1.2 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285)
0.1 3.8 GO:0060076 excitatory synapse(GO:0060076)
0.1 0.8 GO:0045179 apical cortex(GO:0045179)
0.1 1.4 GO:0033270 paranode region of axon(GO:0033270)
0.1 0.4 GO:0001520 outer dense fiber(GO:0001520)
0.1 0.9 GO:0030175 filopodium(GO:0030175)
0.1 0.3 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 0.5 GO:0030061 mitochondrial crista(GO:0030061)
0.1 0.5 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 0.4 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 1.6 GO:0032590 dendrite membrane(GO:0032590)
0.1 0.4 GO:0042587 glycogen granule(GO:0042587)
0.1 5.3 GO:0032587 ruffle membrane(GO:0032587)
0.1 1.7 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 6.0 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 0.2 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 1.2 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.5 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.5 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.2 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.0 2.1 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.7 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 6.4 GO:0005770 late endosome(GO:0005770)
0.0 0.4 GO:0031931 TORC1 complex(GO:0031931)
0.0 3.7 GO:0005604 basement membrane(GO:0005604)
0.0 42.3 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 0.3 GO:0070069 cytochrome complex(GO:0070069)
0.0 0.7 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 2.4 GO:0031301 integral component of organelle membrane(GO:0031301)
0.0 0.7 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 2.1 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.5 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.4 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.2 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.0 0.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.3 GO:0043196 varicosity(GO:0043196)
0.0 0.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834) GTPase complex(GO:1905360)
0.0 0.4 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.0 0.3 GO:0000786 nucleosome(GO:0000786)
0.0 3.7 GO:0000139 Golgi membrane(GO:0000139)
0.0 3.2 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.2 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.2 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 2.1 GO:0031965 nuclear membrane(GO:0031965)
0.0 55.8 GO:0005829 cytosol(GO:0005829)
0.0 0.6 GO:0016235 aggresome(GO:0016235)
0.0 4.2 GO:0043235 receptor complex(GO:0043235)
0.0 0.5 GO:0055037 recycling endosome(GO:0055037)
0.0 0.4 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.9 GO:0000922 spindle pole(GO:0000922)
0.0 0.3 GO:0030057 desmosome(GO:0030057)
0.0 0.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 2.5 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 0.8 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.4 GO:0043209 myelin sheath(GO:0043209)
0.0 0.1 GO:0005869 dynactin complex(GO:0005869)
0.0 0.1 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 24.9 GO:0005615 extracellular space(GO:0005615)
0.0 1.1 GO:0016323 basolateral plasma membrane(GO:0016323)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
5.2 15.5 GO:0003692 left-handed Z-DNA binding(GO:0003692)
3.9 39.0 GO:0019763 immunoglobulin receptor activity(GO:0019763)
2.6 7.9 GO:0050479 glyceryl-ether monooxygenase activity(GO:0050479)
2.4 22.0 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
2.4 17.0 GO:0046978 TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
2.4 16.7 GO:0004556 alpha-amylase activity(GO:0004556)
2.3 9.2 GO:0003884 D-amino-acid oxidase activity(GO:0003884)
2.2 8.6 GO:0031849 olfactory receptor binding(GO:0031849)
2.0 24.0 GO:0030881 beta-2-microglobulin binding(GO:0030881)
1.7 6.9 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
1.7 8.6 GO:0004850 uridine phosphorylase activity(GO:0004850)
1.7 10.0 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
1.4 4.3 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
1.4 4.3 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
1.4 4.1 GO:0019002 GMP binding(GO:0019002)
1.3 5.3 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
1.3 7.9 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
1.3 9.0 GO:0019776 Atg8 ligase activity(GO:0019776)
1.1 7.6 GO:0016936 galactoside binding(GO:0016936)
1.1 4.3 GO:0003844 1,4-alpha-glucan branching enzyme activity(GO:0003844)
1.0 38.3 GO:0008009 chemokine activity(GO:0008009)
1.0 15.3 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
1.0 10.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
1.0 9.6 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.9 7.5 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.9 13.8 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.9 4.4 GO:0038049 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.9 1.7 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.8 3.4 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.8 2.5 GO:0019120 hydrolase activity, acting on acid halide bonds(GO:0016824) hydrolase activity, acting on acid halide bonds, in C-halide compounds(GO:0019120) alkylhalidase activity(GO:0047651)
0.8 2.5 GO:0042015 interleukin-20 binding(GO:0042015)
0.8 11.6 GO:1990459 transferrin receptor binding(GO:1990459)
0.8 18.4 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.8 2.3 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.7 2.1 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.7 2.0 GO:0004658 propionyl-CoA carboxylase activity(GO:0004658)
0.7 7.4 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.7 2.6 GO:0002114 interleukin-33 binding(GO:0002113) interleukin-33 receptor activity(GO:0002114)
0.7 5.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.6 1.9 GO:0019150 D-ribulokinase activity(GO:0019150)
0.6 1.9 GO:0005118 sevenless binding(GO:0005118)
0.6 4.5 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.6 15.4 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.6 2.5 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.6 2.9 GO:1990254 keratin filament binding(GO:1990254)
0.5 2.2 GO:0071614 linoleic acid epoxygenase activity(GO:0071614)
0.5 6.5 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.5 1.1 GO:0051748 UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.5 1.5 GO:0034191 apolipoprotein A-I receptor binding(GO:0034191)
0.5 1.0 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
0.5 1.5 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211)
0.5 3.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.4 6.7 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.4 2.2 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.4 8.9 GO:0042605 peptide antigen binding(GO:0042605)
0.4 0.8 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.4 2.3 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.4 2.7 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.4 1.4 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.4 3.2 GO:1901612 cardiolipin binding(GO:1901612)
0.3 1.0 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.3 1.4 GO:0050632 propanoyl-CoA C-acyltransferase activity(GO:0033814) propionyl-CoA C2-trimethyltridecanoyltransferase activity(GO:0050632)
0.3 1.4 GO:0016508 long-chain-enoyl-CoA hydratase activity(GO:0016508)
0.3 5.2 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.3 2.4 GO:0015288 porin activity(GO:0015288)
0.3 2.0 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.3 1.3 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.3 2.8 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.3 8.1 GO:0005521 lamin binding(GO:0005521)
0.3 2.8 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.3 2.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.3 1.2 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.3 4.0 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.3 2.3 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.3 0.8 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.3 2.0 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.3 7.4 GO:0030247 polysaccharide binding(GO:0030247)
0.3 4.5 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.3 1.0 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.2 1.0 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.2 8.3 GO:0001671 ATPase activator activity(GO:0001671)
0.2 4.7 GO:0005537 mannose binding(GO:0005537)
0.2 3.6 GO:0070628 proteasome binding(GO:0070628)
0.2 1.6 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.2 0.9 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.2 0.9 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.2 1.7 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.2 4.5 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.2 1.1 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.2 5.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.2 0.6 GO:0005110 frizzled-2 binding(GO:0005110)
0.2 1.2 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.2 1.0 GO:0004348 glucosylceramidase activity(GO:0004348)
0.2 0.6 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.2 0.4 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.2 0.8 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.2 16.5 GO:0003725 double-stranded RNA binding(GO:0003725)
0.2 0.7 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.2 0.9 GO:0023029 MHC class Ib protein binding(GO:0023029)
0.2 1.3 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.2 2.3 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.2 0.5 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.2 0.4 GO:0045340 mercury ion binding(GO:0045340)
0.2 0.5 GO:0070052 collagen V binding(GO:0070052)
0.2 2.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.7 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761)
0.1 2.4 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.1 1.0 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 3.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.4 GO:0005302 L-tyrosine transmembrane transporter activity(GO:0005302)
0.1 1.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 1.8 GO:0070412 R-SMAD binding(GO:0070412)
0.1 0.5 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1 0.4 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 1.2 GO:0031419 cobalamin binding(GO:0031419)
0.1 0.5 GO:0008147 structural constituent of bone(GO:0008147)
0.1 0.4 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 0.4 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897) ciliary neurotrophic factor binding(GO:0070119)
0.1 1.9 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 0.6 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 0.6 GO:0034584 piRNA binding(GO:0034584)
0.1 1.6 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 0.5 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
0.1 0.5 GO:0004974 leukotriene receptor activity(GO:0004974)
0.1 0.7 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.1 48.2 GO:0005525 GTP binding(GO:0005525)
0.1 2.3 GO:0003951 NAD+ kinase activity(GO:0003951)
0.1 0.4 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 1.4 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 18.7 GO:0042826 histone deacetylase binding(GO:0042826)
0.1 1.7 GO:0051400 BH domain binding(GO:0051400)
0.1 1.2 GO:0050700 CARD domain binding(GO:0050700)
0.1 1.8 GO:0017166 vinculin binding(GO:0017166)
0.1 0.9 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 1.6 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 0.7 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.1 4.2 GO:0030552 cAMP binding(GO:0030552)
0.1 0.7 GO:0001515 opioid peptide activity(GO:0001515)
0.1 0.9 GO:0140035 ubiquitination-like modification-dependent protein binding(GO:0140035) ubiquitin-dependent protein binding(GO:0140036)
0.1 1.5 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.1 0.4 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 0.5 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 2.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 4.7 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 0.6 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1 0.6 GO:0034046 poly(G) binding(GO:0034046)
0.1 2.9 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.1 0.7 GO:0008097 5S rRNA binding(GO:0008097)
0.1 1.1 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.1 9.0 GO:0020037 heme binding(GO:0020037)
0.1 0.7 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 2.1 GO:0071837 HMG box domain binding(GO:0071837)
0.1 0.4 GO:0004498 calcidiol 1-monooxygenase activity(GO:0004498)
0.1 2.3 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 0.2 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.1 0.3 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.1 2.8 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 13.6 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 0.5 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 3.8 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 1.2 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.1 0.3 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.1 0.4 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 1.0 GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
0.1 2.1 GO:1900750 glutathione peroxidase activity(GO:0004602) glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.1 0.2 GO:0008176 tRNA (guanine-N7-)-methyltransferase activity(GO:0008176)
0.1 0.6 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.1 1.2 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 2.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 1.7 GO:0005542 folic acid binding(GO:0005542)
0.1 0.4 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 15.6 GO:0001047 core promoter binding(GO:0001047)
0.1 0.4 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.1 0.2 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.1 0.9 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.1 0.2 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.1 0.2 GO:0061605 molybdopterin-synthase sulfurtransferase activity(GO:0061604) molybdopterin-synthase adenylyltransferase activity(GO:0061605)
0.1 2.8 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 1.1 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 0.2 GO:0004473 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) oxaloacetate decarboxylase activity(GO:0008948)
0.1 0.4 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 2.0 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 0.7 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 0.6 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.4 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.8 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.7 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 1.0 GO:0008276 protein methyltransferase activity(GO:0008276)
0.0 0.3 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.2 GO:0004661 protein geranylgeranyltransferase activity(GO:0004661)
0.0 0.7 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 3.2 GO:0005518 collagen binding(GO:0005518)
0.0 0.9 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 1.2 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.0 3.5 GO:0008170 N-methyltransferase activity(GO:0008170)
0.0 1.2 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 1.0 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.4 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.0 0.2 GO:0032552 deoxyribonucleotide binding(GO:0032552)
0.0 0.2 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.2 GO:0098821 BMP receptor activity(GO:0098821)
0.0 1.0 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.8 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 2.0 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.7 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.5 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 2.6 GO:0051087 chaperone binding(GO:0051087)
0.0 0.4 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 1.5 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.5 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.1 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.0 0.2 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 0.5 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365)
0.0 1.5 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.6 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.4 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 1.4 GO:0001540 amyloid-beta binding(GO:0001540)
0.0 3.0 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.8 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.6 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 2.2 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 1.1 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 2.7 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 1.1 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.5 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.2 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.2 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.2 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 2.3 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.2 GO:0003882 CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:0003882)
0.0 1.7 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.2 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 0.1 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.2 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.2 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.1 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.0 0.1 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.5 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.4 GO:0005112 Notch binding(GO:0005112)
0.0 0.5 GO:0005507 copper ion binding(GO:0005507)
0.0 0.4 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.1 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 1.4 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.2 GO:0004112 cyclic-nucleotide phosphodiesterase activity(GO:0004112)
0.0 0.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.0 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.1 GO:0070290 phospholipase D activity(GO:0004630) N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.0 GO:0070698 type I activin receptor binding(GO:0070698)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 11.4 ST_TYPE_I_INTERFERON_PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.5 13.7 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.4 29.9 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.4 39.7 PID_IL4_2PATHWAY IL4-mediated signaling events
0.3 16.8 PID_A6B1_A6B4_INTEGRIN_PATHWAY a6b1 and a6b4 Integrin signaling
0.3 13.9 PID_CD8_TCR_DOWNSTREAM_PATHWAY Downstream signaling in naïve CD8+ T cells
0.2 2.0 SA_FAS_SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.2 0.6 PID_IL27_PATHWAY IL27-mediated signaling events
0.1 9.3 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.1 5.1 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.1 6.3 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.1 3.4 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.1 3.0 PID_TRAIL_PATHWAY TRAIL signaling pathway
0.1 4.0 PID_CXCR3_PATHWAY CXCR3-mediated signaling events
0.1 1.3 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 2.8 PID_IL1_PATHWAY IL1-mediated signaling events
0.1 3.0 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.1 1.5 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.1 1.1 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 5.2 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 6.1 SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.1 2.3 PID_IL23_PATHWAY IL23-mediated signaling events
0.1 4.1 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 0.5 PID_FAK_PATHWAY Signaling events mediated by focal adhesion kinase
0.1 1.4 PID_SYNDECAN_2_PATHWAY Syndecan-2-mediated signaling events
0.1 2.0 PID_INTEGRIN3_PATHWAY Beta3 integrin cell surface interactions
0.1 10.5 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 1.8 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 1.4 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.1 0.8 PID_NFKAPPAB_CANONICAL_PATHWAY Canonical NF-kappaB pathway
0.1 1.5 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 4.7 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 1.3 PID_ARF6_PATHWAY Arf6 signaling events
0.0 0.4 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.8 PID_P38_ALPHA_BETA_PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.4 PID_ALK1_PATHWAY ALK1 signaling events
0.0 0.7 ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.3 PID_SHP2_PATHWAY SHP2 signaling
0.0 1.7 PID_P75_NTR_PATHWAY p75(NTR)-mediated signaling
0.0 1.7 PID_RB_1PATHWAY Regulation of retinoblastoma protein
0.0 0.4 PID_AP1_PATHWAY AP-1 transcription factor network
0.0 0.5 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 3.3 PID_P53_DOWNSTREAM_PATHWAY Direct p53 effectors
0.0 1.2 PID_MTOR_4PATHWAY mTOR signaling pathway
0.0 0.7 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.0 0.2 PID_ALK2_PATHWAY ALK2 signaling events
0.0 3.4 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.7 PID_VEGFR1_2_PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.9 PID_NOTCH_PATHWAY Notch signaling pathway
0.0 0.4 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 0.4 PID_P73PATHWAY p73 transcription factor network
0.0 0.5 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.0 0.2 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.0 0.3 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.4 PID_ILK_PATHWAY Integrin-linked kinase signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
4.1 12.2 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
1.1 21.7 REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
1.0 13.5 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade
0.9 16.8 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism
0.8 15.5 REACTOME_REGULATION_OF_IFNA_SIGNALING Genes involved in Regulation of IFNA signaling
0.8 14.7 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.7 15.3 REACTOME_RIP_MEDIATED_NFKB_ACTIVATION_VIA_DAI Genes involved in RIP-mediated NFkB activation via DAI
0.6 27.0 REACTOME_INTERFERON_GAMMA_SIGNALING Genes involved in Interferon gamma signaling
0.5 2.2 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.5 15.7 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.5 5.1 REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.5 6.0 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.4 20.6 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.4 9.7 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.4 7.1 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism
0.3 15.5 REACTOME_CROSS_PRESENTATION_OF_SOLUBLE_EXOGENOUS_ANTIGENS_ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.3 3.3 REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN1_SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.3 2.4 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle
0.3 1.0 REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.2 3.1 REACTOME_PD1_SIGNALING Genes involved in PD-1 signaling
0.2 6.2 REACTOME_RIG_I_MDA5_MEDIATED_INDUCTION_OF_IFN_ALPHA_BETA_PATHWAYS Genes involved in RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
0.2 10.2 REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.2 1.9 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism
0.2 1.5 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.2 7.2 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.2 15.4 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.2 1.9 REACTOME_TAK1_ACTIVATES_NFKB_BY_PHOSPHORYLATION_AND_ACTIVATION_OF_IKKS_COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.1 1.6 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation
0.1 2.2 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 2.9 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 0.7 REACTOME_ER_PHAGOSOME_PATHWAY Genes involved in ER-Phagosome pathway
0.1 9.7 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 2.0 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 1.0 REACTOME_AMYLOIDS Genes involved in Amyloids
0.1 0.8 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 4.7 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.1 2.5 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 2.9 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.1 0.9 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 8.5 REACTOME_GLUCOSE_METABOLISM Genes involved in Glucose metabolism
0.1 0.9 REACTOME_COMMON_PATHWAY Genes involved in Common Pathway
0.1 1.5 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.1 2.2 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.1 2.7 REACTOME_IL1_SIGNALING Genes involved in Interleukin-1 signaling
0.1 1.1 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 1.5 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 2.4 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.1 1.5 REACTOME_SHC1_EVENTS_IN_ERBB4_SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.1 0.5 REACTOME_ACTIVATED_TAK1_MEDIATES_P38_MAPK_ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.1 4.3 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 1.7 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1 1.3 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 0.5 REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.1 0.8 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.1 2.6 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.1 0.3 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.1 1.3 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 2.4 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 0.4 REACTOME_GRB2_SOS_PROVIDES_LINKAGE_TO_MAPK_SIGNALING_FOR_INTERGRINS_ Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 5.0 REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION Genes involved in MHC class II antigen presentation
0.0 1.1 REACTOME_FORMATION_OF_INCISION_COMPLEX_IN_GG_NER Genes involved in Formation of incision complex in GG-NER
0.0 0.6 REACTOME_CTLA4_INHIBITORY_SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 2.2 REACTOME_PYRUVATE_METABOLISM_AND_CITRIC_ACID_TCA_CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.0 2.0 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.3 REACTOME_ARMS_MEDIATED_ACTIVATION Genes involved in ARMS-mediated activation
0.0 0.9 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 1.1 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 0.9 REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.4 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.3 REACTOME_PROLACTIN_RECEPTOR_SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.7 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.6 REACTOME_REGULATION_OF_WATER_BALANCE_BY_RENAL_AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 0.6 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.0 1.0 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.7 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.9 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.5 REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.7 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.0 0.4 REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.9 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.0 1.0 REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.2 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.5 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.6 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.5 REACTOME_METABOLISM_OF_NON_CODING_RNA Genes involved in Metabolism of non-coding RNA
0.0 0.4 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.1 REACTOME_RAS_ACTIVATION_UOPN_CA2_INFUX_THROUGH_NMDA_RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 1.0 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.0 0.1 REACTOME_DOWNSTREAM_SIGNALING_EVENTS_OF_B_CELL_RECEPTOR_BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0 0.3 REACTOME_GLUCOSE_TRANSPORT Genes involved in Glucose transport
0.0 0.2 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 2.4 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.1 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.2 REACTOME_ACTIVATION_OF_GENES_BY_ATF4 Genes involved in Activation of Genes by ATF4