Motif ID: Klf1

Z-value: 2.559


Transcription factors associated with Klf1:

Gene SymbolEntrez IDGene Name
Klf1 ENSMUSG00000054191.7 Klf1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Klf1mm10_v2_chr8_+_84901928_849019920.911.9e-14Click!


Activity profile for motif Klf1.

activity profile for motif Klf1


Sorted Z-values histogram for motif Klf1

Sorted Z-values for motif Klf1



Network of associatons between targets according to the STRING database.



First level regulatory network of Klf1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_-_109849440 24.443 ENSMUST00000112022.2
Camp
cathelicidin antimicrobial peptide
chr7_-_142578139 24.053 ENSMUST00000136359.1
H19
H19 fetal liver mRNA
chr14_+_80000292 19.656 ENSMUST00000088735.3
Olfm4
olfactomedin 4
chr7_-_142656018 17.802 ENSMUST00000178921.1
Igf2
insulin-like growth factor 2
chr11_+_11684967 17.657 ENSMUST00000126058.1
ENSMUST00000141436.1
Ikzf1

IKAROS family zinc finger 1

chr8_+_22974844 15.704 ENSMUST00000110688.2
ENSMUST00000121802.2
Ank1

ankyrin 1, erythroid

chr9_+_111019284 15.076 ENSMUST00000035077.3
Ltf
lactotransferrin
chr17_-_26201328 14.555 ENSMUST00000025019.2
Arhgdig
Rho GDP dissociation inhibitor (GDI) gamma
chr12_-_4841583 14.289 ENSMUST00000020964.5
Fkbp1b
FK506 binding protein 1b
chr6_+_86078070 13.216 ENSMUST00000032069.5
Add2
adducin 2 (beta)
chr14_-_70630149 12.255 ENSMUST00000022694.9
Dmtn
dematin actin binding protein
chr11_+_58274799 12.058 ENSMUST00000108834.1
4930438A08Rik
RIKEN cDNA 4930438A08 gene
chr8_+_123411424 11.840 ENSMUST00000071134.3
Tubb3
tubulin, beta 3 class III
chr16_+_17646564 11.674 ENSMUST00000182117.1
ENSMUST00000182671.1
ENSMUST00000182344.1
Ccdc74a


coiled-coil domain containing 74A


chr7_-_103813913 11.447 ENSMUST00000098192.3
Hbb-bt
hemoglobin, beta adult t chain
chrX_-_7967817 10.972 ENSMUST00000033502.7
Gata1
GATA binding protein 1
chr16_+_17646464 10.864 ENSMUST00000056962.4
Ccdc74a
coiled-coil domain containing 74A
chr11_+_74619594 10.858 ENSMUST00000100866.2
E130309D14Rik
RIKEN cDNA E130309D14 gene
chr8_+_93810832 10.841 ENSMUST00000034198.8
ENSMUST00000125716.1
Gnao1

guanine nucleotide binding protein, alpha O

chr7_-_141016892 10.819 ENSMUST00000081924.3
Ifitm6
interferon induced transmembrane protein 6
chr11_-_102365111 10.639 ENSMUST00000006749.9
Slc4a1
solute carrier family 4 (anion exchanger), member 1
chr12_+_109540979 10.578 ENSMUST00000129245.1
ENSMUST00000143836.1
ENSMUST00000124106.1
Meg3


maternally expressed 3


chrX_+_73639414 10.470 ENSMUST00000019701.8
Dusp9
dual specificity phosphatase 9
chr7_-_24760311 10.330 ENSMUST00000063956.5
Cd177
CD177 antigen
chr7_-_143460989 10.322 ENSMUST00000167912.1
ENSMUST00000037287.6
Cdkn1c

cyclin-dependent kinase inhibitor 1C (P57)

chr14_-_60086832 10.243 ENSMUST00000080368.5
Atp8a2
ATPase, aminophospholipid transporter-like, class I, type 8A, member 2
chr2_-_150668198 10.187 ENSMUST00000028944.3
Acss1
acyl-CoA synthetase short-chain family member 1
chr7_-_17062384 10.167 ENSMUST00000153833.1
ENSMUST00000108492.2
Hif3a

hypoxia inducible factor 3, alpha subunit

chr7_-_38107490 10.131 ENSMUST00000108023.3
Ccne1
cyclin E1
chr7_+_143005770 9.798 ENSMUST00000143512.1
Tspan32
tetraspanin 32
chr9_-_123678873 9.663 ENSMUST00000040960.6
Slc6a20a
solute carrier family 6 (neurotransmitter transporter), member 20A
chr7_+_24370255 9.611 ENSMUST00000171904.1
Kcnn4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr5_-_134915512 9.444 ENSMUST00000008987.4
Cldn13
claudin 13
chr11_+_32276400 9.393 ENSMUST00000020531.2
Hba-x
hemoglobin X, alpha-like embryonic chain in Hba complex
chr10_+_75948292 9.173 ENSMUST00000000926.2
Vpreb3
pre-B lymphocyte gene 3
chr7_+_142442330 9.160 ENSMUST00000149529.1
Tnni2
troponin I, skeletal, fast 2
chr17_-_26201363 9.085 ENSMUST00000121959.1
Arhgdig
Rho GDP dissociation inhibitor (GDI) gamma
chr2_+_163054682 9.082 ENSMUST00000018005.3
Mybl2
myeloblastosis oncogene-like 2
chr17_-_6782775 8.968 ENSMUST00000064234.6
Ezr
ezrin
chrX_-_7671341 8.943 ENSMUST00000033486.5
Plp2
proteolipid protein 2
chr7_+_25152456 8.732 ENSMUST00000098678.1
D930028M14Rik
RIKEN cDNA D930028M14 gene
chr8_+_84723003 8.720 ENSMUST00000098571.4
G430095P16Rik
RIKEN cDNA G430095P16 gene
chr17_-_35066170 8.647 ENSMUST00000174190.1
ENSMUST00000097337.1
AU023871

expressed sequence AU023871

chrX_+_8271642 8.588 ENSMUST00000115590.1
Slc38a5
solute carrier family 38, member 5
chr4_+_115057683 8.536 ENSMUST00000161601.1
Tal1
T cell acute lymphocytic leukemia 1
chr11_-_87875524 8.296 ENSMUST00000049768.3
Epx
eosinophil peroxidase
chr6_-_72958465 8.288 ENSMUST00000114050.1
Tmsb10
thymosin, beta 10
chr11_+_32276893 8.111 ENSMUST00000145569.1
Hba-x
hemoglobin X, alpha-like embryonic chain in Hba complex
chr7_-_142578093 8.090 ENSMUST00000149974.1
ENSMUST00000152754.1
H19

H19 fetal liver mRNA

chr15_+_89322969 8.086 ENSMUST00000066991.5
Adm2
adrenomedullin 2
chr6_+_86628174 8.061 ENSMUST00000043400.6
Asprv1
aspartic peptidase, retroviral-like 1
chr6_+_72549652 8.024 ENSMUST00000134809.1
Capg
capping protein (actin filament), gelsolin-like
chr14_+_55765956 7.983 ENSMUST00000057569.3
Ltb4r1
leukotriene B4 receptor 1
chr11_-_116077562 7.929 ENSMUST00000174822.1
Unc13d
unc-13 homolog D (C. elegans)
chr9_-_123678782 7.904 ENSMUST00000170591.1
ENSMUST00000171647.1
Slc6a20a

solute carrier family 6 (neurotransmitter transporter), member 20A

chr8_-_71723308 7.876 ENSMUST00000125092.1
Fcho1
FCH domain only 1
chr4_-_117929726 7.867 ENSMUST00000070816.2
Artn
artemin
chr14_-_60087347 7.824 ENSMUST00000149414.1
Atp8a2
ATPase, aminophospholipid transporter-like, class I, type 8A, member 2
chr7_-_126704179 7.782 ENSMUST00000106364.1
Coro1a
coronin, actin binding protein 1A
chr10_+_75564086 7.761 ENSMUST00000141062.1
ENSMUST00000152657.1
Ggt1

gamma-glutamyltransferase 1

chr17_-_25942821 7.752 ENSMUST00000148382.1
ENSMUST00000145745.1
Pigq

phosphatidylinositol glycan anchor biosynthesis, class Q

chr17_-_48432723 7.695 ENSMUST00000046549.3
Apobec2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2
chr7_+_143005638 7.662 ENSMUST00000075172.5
ENSMUST00000105923.1
Tspan32

tetraspanin 32

chr15_-_103252810 7.652 ENSMUST00000154510.1
Nfe2
nuclear factor, erythroid derived 2
chr6_+_72549430 7.643 ENSMUST00000155705.1
Capg
capping protein (actin filament), gelsolin-like
chr14_-_70627008 7.642 ENSMUST00000110984.2
Dmtn
dematin actin binding protein
chr7_-_103843154 7.642 ENSMUST00000063957.4
Hbb-bh1
hemoglobin Z, beta-like embryonic chain
chrX_-_150812932 7.470 ENSMUST00000131241.1
ENSMUST00000147152.1
ENSMUST00000143843.1
Maged2


melanoma antigen, family D, 2


chrX_-_74246364 7.444 ENSMUST00000130007.1
Flna
filamin, alpha
chr17_+_48299952 7.424 ENSMUST00000170941.1
Treml2
triggering receptor expressed on myeloid cells-like 2
chr10_-_81500132 7.383 ENSMUST00000053646.5
S1pr4
sphingosine-1-phosphate receptor 4
chrX_-_102251852 7.277 ENSMUST00000101336.3
ENSMUST00000136277.1
Cited1

Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1

chr9_-_67832325 7.225 ENSMUST00000054500.5
C2cd4a
C2 calcium-dependent domain containing 4A
chr8_-_105471481 7.211 ENSMUST00000014990.6
Tppp3
tubulin polymerization-promoting protein family member 3
chr15_+_82341179 7.168 ENSMUST00000050349.2
Fam109b
family with sequence similarity 109, member B
chr12_-_16999991 7.163 ENSMUST00000067572.6
Pqlc3
PQ loop repeat containing
chr10_+_3973086 7.088 ENSMUST00000117291.1
ENSMUST00000120585.1
ENSMUST00000043735.7
Mthfd1l


methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like


chr2_-_131160006 6.977 ENSMUST00000103188.3
ENSMUST00000133602.1
ENSMUST00000028800.5
1700037H04Rik


RIKEN cDNA 1700037H04 gene


chr10_-_80421847 6.966 ENSMUST00000156244.1
Tcf3
transcription factor 3
chr11_-_116077606 6.816 ENSMUST00000106450.1
Unc13d
unc-13 homolog D (C. elegans)
chr8_+_123332676 6.776 ENSMUST00000010298.6
Spire2
spire homolog 2 (Drosophila)
chr17_+_29114142 6.696 ENSMUST00000141797.1
ENSMUST00000132262.1
ENSMUST00000141239.1
ENSMUST00000138816.1
Gm16194



predicted gene 16194



chr16_-_18622403 6.670 ENSMUST00000167388.1
Gp1bb
glycoprotein Ib, beta polypeptide
chr12_+_24831583 6.653 ENSMUST00000110942.3
ENSMUST00000078902.6
Mboat2

membrane bound O-acyltransferase domain containing 2

chr11_+_62077018 6.622 ENSMUST00000092415.5
Specc1
sperm antigen with calponin homology and coiled-coil domains 1
chr3_+_108383829 6.549 ENSMUST00000090561.3
ENSMUST00000102629.1
ENSMUST00000128089.1
Psrc1


proline/serine-rich coiled-coil 1


chr5_-_139325616 6.497 ENSMUST00000110865.1
Adap1
ArfGAP with dual PH domains 1
chr7_+_127091426 6.489 ENSMUST00000056288.5
AI467606
expressed sequence AI467606
chr7_-_126704522 6.437 ENSMUST00000135087.1
Coro1a
coronin, actin binding protein 1A
chr2_+_131186942 6.401 ENSMUST00000028804.8
ENSMUST00000079857.8
Cdc25b

cell division cycle 25B

chr11_+_62575981 6.369 ENSMUST00000102643.1
Trpv2
transient receptor potential cation channel, subfamily V, member 2
chr2_+_131491958 6.367 ENSMUST00000110181.1
ENSMUST00000110180.1
Smox

spermine oxidase

chr5_-_137741601 6.272 ENSMUST00000119498.1
ENSMUST00000061789.7
Nyap1

neuronal tyrosine-phosphorylated phosphoinositide 3-kinase adaptor 1

chr3_-_132950043 6.230 ENSMUST00000117164.1
ENSMUST00000093971.4
ENSMUST00000042729.9
ENSMUST00000042744.9
ENSMUST00000117811.1
Npnt




nephronectin




chr4_-_152448808 6.190 ENSMUST00000159840.1
ENSMUST00000105648.2
Kcnab2

potassium voltage-gated channel, shaker-related subfamily, beta member 2

chr7_-_135716374 6.184 ENSMUST00000033310.7
Mki67
antigen identified by monoclonal antibody Ki 67
chrX_-_102252154 6.171 ENSMUST00000050551.3
Cited1
Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1
chr7_+_100495987 6.166 ENSMUST00000133044.1
Ucp2
uncoupling protein 2 (mitochondrial, proton carrier)
chr6_+_72549252 6.152 ENSMUST00000114071.1
Capg
capping protein (actin filament), gelsolin-like
chr11_+_120948480 6.112 ENSMUST00000070653.6
Slc16a3
solute carrier family 16 (monocarboxylic acid transporters), member 3
chr5_+_76656512 6.099 ENSMUST00000086909.4
Gm10430
predicted gene 10430
chr7_+_143005677 6.099 ENSMUST00000082008.5
ENSMUST00000105925.1
ENSMUST00000105924.1
Tspan32


tetraspanin 32


chr7_+_13278778 6.065 ENSMUST00000098814.4
ENSMUST00000146998.1
ENSMUST00000185145.1
Lig1


ligase I, DNA, ATP-dependent


chr7_-_4752972 6.053 ENSMUST00000183971.1
ENSMUST00000182173.1
ENSMUST00000182738.1
ENSMUST00000184143.1
ENSMUST00000182111.1
ENSMUST00000182048.1
ENSMUST00000063324.7
Cox6b2






cytochrome c oxidase subunit VIb polypeptide 2






chr17_-_48146306 6.030 ENSMUST00000063481.7
9830107B12Rik
RIKEN cDNA 9830107B12 gene
chr17_-_79355082 5.986 ENSMUST00000068958.7
Cdc42ep3
CDC42 effector protein (Rho GTPase binding) 3
chr1_-_119053619 5.979 ENSMUST00000062483.8
Gli2
GLI-Kruppel family member GLI2
chr4_-_98817537 5.977 ENSMUST00000102790.3
Kank4
KN motif and ankyrin repeat domains 4
chr11_-_116077954 5.953 ENSMUST00000106451.1
ENSMUST00000075036.2
Unc13d

unc-13 homolog D (C. elegans)

chr7_-_80803253 5.905 ENSMUST00000167377.1
Iqgap1
IQ motif containing GTPase activating protein 1
chr7_-_120982260 5.904 ENSMUST00000033169.8
Cdr2
cerebellar degeneration-related 2
chr17_+_40811089 5.869 ENSMUST00000024721.7
Rhag
Rhesus blood group-associated A glycoprotein
chr10_+_75573448 5.807 ENSMUST00000006508.3
Ggt1
gamma-glutamyltransferase 1
chr10_-_128401218 5.797 ENSMUST00000042666.5
Slc39a5
solute carrier family 39 (metal ion transporter), member 5
chr2_-_114052804 5.753 ENSMUST00000090269.6
Actc1
actin, alpha, cardiac muscle 1
chr17_+_35861318 5.730 ENSMUST00000074259.8
ENSMUST00000174873.1
Nrm

nurim (nuclear envelope membrane protein)

chr9_+_65101453 5.712 ENSMUST00000077696.6
ENSMUST00000035499.4
ENSMUST00000166273.1
Igdcc4


immunoglobulin superfamily, DCC subclass, member 4


chr7_+_18884679 5.706 ENSMUST00000032573.6
Pglyrp1
peptidoglycan recognition protein 1
chr12_-_76709997 5.691 ENSMUST00000166101.1
Sptb
spectrin beta, erythrocytic
chr11_-_116077927 5.685 ENSMUST00000156545.1
Unc13d
unc-13 homolog D (C. elegans)
chr6_-_72958097 5.666 ENSMUST00000114049.1
Tmsb10
thymosin, beta 10
chr2_+_131491764 5.664 ENSMUST00000028806.5
ENSMUST00000110179.2
ENSMUST00000110189.2
ENSMUST00000110182.2
ENSMUST00000110183.2
ENSMUST00000110186.2
ENSMUST00000110188.1
Smox






spermine oxidase






chr15_-_79285502 5.661 ENSMUST00000165408.1
Baiap2l2
BAI1-associated protein 2-like 2
chr6_+_39420378 5.645 ENSMUST00000090237.2
Gm10244
predicted gene 10244
chr2_+_30416031 5.608 ENSMUST00000042055.3
Ppp2r4
protein phosphatase 2A, regulatory subunit B (PR 53)
chr17_+_56303321 5.568 ENSMUST00000001258.8
Uhrf1
ubiquitin-like, containing PHD and RING finger domains, 1
chr5_+_137288273 5.496 ENSMUST00000024099.4
ENSMUST00000085934.3
Ache

acetylcholinesterase

chr2_-_164779721 5.478 ENSMUST00000103095.4
Tnnc2
troponin C2, fast
chr1_+_75382114 5.463 ENSMUST00000113590.1
ENSMUST00000148515.1
Speg

SPEG complex locus

chr17_+_35861343 5.433 ENSMUST00000172931.1
Nrm
nurim (nuclear envelope membrane protein)
chr2_+_25242929 5.392 ENSMUST00000114355.1
ENSMUST00000060818.1
Rnf208

ring finger protein 208

chr10_-_12964252 5.357 ENSMUST00000163425.1
ENSMUST00000042861.5
Stx11

syntaxin 11

chr9_+_69454066 5.356 ENSMUST00000134907.1
Anxa2
annexin A2
chr4_+_115057410 5.330 ENSMUST00000136946.1
Tal1
T cell acute lymphocytic leukemia 1
chr7_-_45211877 5.308 ENSMUST00000033057.7
Dkkl1
dickkopf-like 1
chr11_-_102082464 5.281 ENSMUST00000100398.4
Mpp2
membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
chr8_-_122460666 5.265 ENSMUST00000006762.5
Snai3
snail homolog 3 (Drosophila)
chr2_-_156839790 5.232 ENSMUST00000134838.1
ENSMUST00000137463.1
ENSMUST00000149275.2
Gm14230


predicted gene 14230


chr8_-_53638945 5.182 ENSMUST00000047768.4
Neil3
nei like 3 (E. coli)
chr7_-_103827922 5.143 ENSMUST00000023934.6
ENSMUST00000153218.1
Hbb-bs

hemoglobin, beta adult s chain

chr12_-_17000108 5.119 ENSMUST00000054536.4
Pqlc3
PQ loop repeat containing
chr4_-_43046196 5.079 ENSMUST00000036462.5
Fam214b
family with sequence similarity 214, member B
chr7_+_43797567 5.072 ENSMUST00000085461.2
Klk8
kallikrein related-peptidase 8
chr9_-_21291124 5.069 ENSMUST00000086374.6
Cdkn2d
cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr4_+_108579445 5.065 ENSMUST00000102744.3
Orc1
origin recognition complex, subunit 1
chr10_+_83722865 5.037 ENSMUST00000150459.1
1500009L16Rik
RIKEN cDNA 1500009L16 gene
chr1_-_119053339 5.021 ENSMUST00000161301.1
ENSMUST00000161451.1
ENSMUST00000162607.1
Gli2


GLI-Kruppel family member GLI2


chr6_-_39420418 5.019 ENSMUST00000031985.6
Mkrn1
makorin, ring finger protein, 1
chr15_+_78926720 4.949 ENSMUST00000089377.5
Lgals1
lectin, galactose binding, soluble 1
chr7_+_24777172 4.932 ENSMUST00000038069.7
Ceacam10
carcinoembryonic antigen-related cell adhesion molecule 10
chr11_+_87755567 4.927 ENSMUST00000123700.1
A430104N18Rik
RIKEN cDNA A430104N18 gene
chr6_-_39420281 4.926 ENSMUST00000114822.1
ENSMUST00000051671.4
Mkrn1

makorin, ring finger protein, 1

chr4_-_117929466 4.910 ENSMUST00000097913.2
Artn
artemin
chr16_-_42340595 4.897 ENSMUST00000102817.4
Gap43
growth associated protein 43
chr5_-_137741102 4.891 ENSMUST00000149512.1
Nyap1
neuronal tyrosine-phosphorylated phosphoinositide 3-kinase adaptor 1
chr2_-_29869785 4.882 ENSMUST00000047607.1
2600006K01Rik
RIKEN cDNA 2600006K01 gene
chrX_+_161162744 4.880 ENSMUST00000074802.5
ENSMUST00000019101.4
ENSMUST00000112345.1
Scml2


sex comb on midleg-like 2 (Drosophila)


chr17_-_56830916 4.880 ENSMUST00000002444.7
ENSMUST00000086801.5
Rfx2

regulatory factor X, 2 (influences HLA class II expression)

chr1_-_193035651 4.848 ENSMUST00000016344.7
Syt14
synaptotagmin XIV
chr6_+_122391379 4.806 ENSMUST00000043553.3
1700063H04Rik
RIKEN cDNA 1700063H04 gene
chr9_+_69453620 4.799 ENSMUST00000034756.8
ENSMUST00000123470.1
Anxa2

annexin A2

chr19_-_4283033 4.756 ENSMUST00000167215.1
ENSMUST00000056888.6
Ankrd13d

ankyrin repeat domain 13 family, member D

chr5_+_34949435 4.743 ENSMUST00000030984.7
Rgs12
regulator of G-protein signaling 12
chr7_+_29134971 4.740 ENSMUST00000160194.1
Rasgrp4
RAS guanyl releasing protein 4
chr17_+_25717171 4.727 ENSMUST00000172002.1
Gng13
guanine nucleotide binding protein (G protein), gamma 13
chr10_-_128400448 4.717 ENSMUST00000167859.1
Slc39a5
solute carrier family 39 (metal ion transporter), member 5
chr5_-_107726017 4.711 ENSMUST00000159263.2
Gfi1
growth factor independent 1
chr13_-_49248146 4.706 ENSMUST00000119721.1
ENSMUST00000058196.6
Susd3

sushi domain containing 3

chr3_-_152166230 4.692 ENSMUST00000046614.9
Gipc2
GIPC PDZ domain containing family, member 2
chr12_-_32061221 4.664 ENSMUST00000003079.5
ENSMUST00000036497.9
Prkar2b

protein kinase, cAMP dependent regulatory, type II beta

chr4_-_154636831 4.649 ENSMUST00000030902.6
ENSMUST00000105637.1
ENSMUST00000070313.7
ENSMUST00000105636.1
ENSMUST00000105638.2
ENSMUST00000097759.2
ENSMUST00000124771.1
Prdm16






PR domain containing 16






chr5_+_34573744 4.640 ENSMUST00000147574.1
ENSMUST00000146295.1
Add1

adducin 1 (alpha)

chr10_-_79788924 4.633 ENSMUST00000020573.6
Prss57
protease, serine 57
chr10_-_80577285 4.633 ENSMUST00000038558.8
Klf16
Kruppel-like factor 16
chr13_+_52583437 4.613 ENSMUST00000118756.1
Syk
spleen tyrosine kinase
chr15_-_98778150 4.594 ENSMUST00000023732.5
Wnt10b
wingless related MMTV integration site 10b
chr7_-_99238564 4.564 ENSMUST00000064231.7
Mogat2
monoacylglycerol O-acyltransferase 2
chr7_+_78914216 4.556 ENSMUST00000120331.2
Isg20
interferon-stimulated protein
chr7_+_113513854 4.529 ENSMUST00000067929.8
ENSMUST00000129087.1
ENSMUST00000164745.1
ENSMUST00000136158.1
Far1



fatty acyl CoA reductase 1



chr5_+_34573664 4.526 ENSMUST00000114338.2
Add1
adducin 1 (alpha)
chr14_+_32321987 4.518 ENSMUST00000022480.7
Ogdhl
oxoglutarate dehydrogenase-like
chr17_-_48167187 4.500 ENSMUST00000053612.6
ENSMUST00000027764.8
A530064D06Rik

RIKEN cDNA A530064D06 gene

chr9_+_56865104 4.485 ENSMUST00000035661.5
Cspg4
chondroitin sulfate proteoglycan 4
chr11_+_69964758 4.480 ENSMUST00000108597.1
ENSMUST00000060651.5
ENSMUST00000108596.1
Cldn7


claudin 7


chr11_-_3504766 4.461 ENSMUST00000044507.5
Inpp5j
inositol polyphosphate 5-phosphatase J
chr19_-_5273080 4.448 ENSMUST00000025786.7
Pacs1
phosphofurin acidic cluster sorting protein 1
chr16_-_22657182 4.444 ENSMUST00000023578.7
Dgkg
diacylglycerol kinase, gamma
chr9_+_54699514 4.426 ENSMUST00000154690.1
Dnaja4
DnaJ (Hsp40) homolog, subfamily A, member 4
chr5_-_67815852 4.421 ENSMUST00000141443.1
Atp8a1
ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
chr7_-_100514800 4.415 ENSMUST00000054923.7
Dnajb13
DnaJ (Hsp40) related, subfamily B, member 13
chr2_-_181693810 4.386 ENSMUST00000108776.1
ENSMUST00000108771.1
ENSMUST00000108779.1
ENSMUST00000108769.1
ENSMUST00000108772.1
ENSMUST00000002532.2
Rgs19





regulator of G-protein signaling 19





chr6_-_39419967 4.336 ENSMUST00000122996.1
Mkrn1
makorin, ring finger protein, 1
chr4_+_134315112 4.331 ENSMUST00000105875.1
ENSMUST00000030638.6
Trim63

tripartite motif-containing 63

chr11_-_17052344 4.314 ENSMUST00000020321.6
Plek
pleckstrin
chrX_-_74246534 4.313 ENSMUST00000101454.2
ENSMUST00000033699.6
Flna

filamin, alpha

chr9_+_119063429 4.313 ENSMUST00000141185.1
ENSMUST00000126251.1
ENSMUST00000136561.1
Vill


villin-like


chr6_+_134929089 4.287 ENSMUST00000183867.1
ENSMUST00000184991.1
ENSMUST00000183905.1
RP23-45G16.5


RP23-45G16.5


chr15_-_79285470 4.285 ENSMUST00000170955.1
Baiap2l2
BAI1-associated protein 2-like 2
chr15_+_80091320 4.280 ENSMUST00000009728.6
ENSMUST00000009727.5
Syngr1

synaptogyrin 1

chr19_+_8802486 4.270 ENSMUST00000172175.1
Zbtb3
zinc finger and BTB domain containing 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
6.6 19.9 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
5.9 17.7 GO:0045660 positive regulation of neutrophil differentiation(GO:0045660)
4.6 13.9 GO:0060217 hemangioblast cell differentiation(GO:0060217)
4.6 9.2 GO:0051023 negative regulation of immunoglobulin production(GO:0002638) regulation of immunoglobulin secretion(GO:0051023) negative regulation of immunoglobulin secretion(GO:0051025)
4.3 8.6 GO:0070560 protein secretion by platelet(GO:0070560)
4.3 12.8 GO:0097021 lymphocyte migration into lymphoid organs(GO:0097021)
3.9 11.8 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
3.8 11.5 GO:1905595 regulation of low-density lipoprotein particle receptor binding(GO:1905595)
3.7 11.0 GO:0030221 basophil differentiation(GO:0030221)
3.3 13.3 GO:1902896 terminal web assembly(GO:1902896)
3.2 25.9 GO:0061789 dense core granule priming(GO:0061789)
3.0 29.9 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
3.0 11.9 GO:0006529 asparagine biosynthetic process(GO:0006529)
2.9 23.2 GO:0015671 oxygen transport(GO:0015671)
2.8 22.5 GO:0061092 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
2.8 8.3 GO:0002215 defense response to nematode(GO:0002215)
2.7 11.0 GO:0060032 notochord regression(GO:0060032)
2.7 13.4 GO:0071105 response to interleukin-11(GO:0071105)
2.6 7.7 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
2.5 15.1 GO:0019732 antifungal humoral response(GO:0019732) positive regulation of chondrocyte proliferation(GO:1902732)
2.5 14.9 GO:0032796 uropod organization(GO:0032796)
2.5 32.2 GO:2000653 regulation of genetic imprinting(GO:2000653)
2.3 6.8 GO:1902688 regulation of fermentation(GO:0043465) regulation of NAD metabolic process(GO:1902688) regulation of glucose catabolic process to lactate via pyruvate(GO:1904023)
2.3 6.8 GO:0070649 formin-nucleated actin cable assembly(GO:0070649) formin-nucleated actin cable organization(GO:0110009)
2.2 17.8 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
2.1 12.4 GO:0034441 plasma lipoprotein oxidation(GO:0034441)
2.1 6.2 GO:1990705 cholangiocyte proliferation(GO:1990705)
2.0 8.0 GO:0032672 regulation of interleukin-3 production(GO:0032672) positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401) positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425) cellular response to molecule of fungal origin(GO:0071226)
1.9 5.7 GO:0051714 regulation of cytolysis in other organism(GO:0051710) positive regulation of cytolysis in other organism(GO:0051714)
1.9 15.0 GO:0070294 renal sodium ion absorption(GO:0070294)
1.9 13.1 GO:0051775 response to redox state(GO:0051775)
1.8 5.5 GO:0098971 anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
1.8 48.3 GO:0051016 barbed-end actin filament capping(GO:0051016)
1.7 13.6 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
1.6 29.6 GO:0015816 glycine transport(GO:0015816)
1.6 8.0 GO:0061737 leukotriene signaling pathway(GO:0061737)
1.6 6.2 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
1.6 4.7 GO:0070489 T cell aggregation(GO:0070489)
1.5 1.5 GO:2001188 negative regulation of immunological synapse formation(GO:2000521) regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001188) negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001189)
1.5 4.6 GO:0046462 monoacylglycerol metabolic process(GO:0046462)
1.5 10.6 GO:0046208 spermine catabolic process(GO:0046208)
1.5 5.9 GO:0030070 insulin processing(GO:0030070)
1.5 4.4 GO:1904158 axonemal central apparatus assembly(GO:1904158)
1.5 24.9 GO:0051873 disruption by host of symbiont cells(GO:0051852) killing by host of symbiont cells(GO:0051873)
1.4 2.9 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
1.4 11.3 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
1.4 7.0 GO:0070295 renal water absorption(GO:0070295)
1.4 4.2 GO:1901074 regulation of engulfment of apoptotic cell(GO:1901074)
1.4 5.5 GO:0070829 heterochromatin maintenance(GO:0070829)
1.4 10.9 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
1.3 6.6 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
1.3 3.9 GO:2000417 negative regulation of eosinophil migration(GO:2000417)
1.3 1.3 GO:2000642 negative regulation of cytoplasmic transport(GO:1903650) negative regulation of early endosome to late endosome transport(GO:2000642)
1.2 7.4 GO:0008291 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
1.2 4.9 GO:0032053 ciliary basal body organization(GO:0032053)
1.2 2.4 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
1.2 2.4 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
1.2 4.9 GO:0072344 rescue of stalled ribosome(GO:0072344)
1.2 7.3 GO:0002326 B cell lineage commitment(GO:0002326)
1.2 3.6 GO:0070650 actin filament bundle distribution(GO:0070650)
1.2 9.5 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
1.1 4.6 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
1.1 2.3 GO:0071593 lymphocyte aggregation(GO:0071593)
1.1 3.3 GO:1990523 bone regeneration(GO:1990523)
1.1 4.3 GO:0010286 heat acclimation(GO:0010286)
1.1 5.3 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
1.0 2.1 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
1.0 2.0 GO:0090202 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
1.0 3.0 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
1.0 8.1 GO:0010624 regulation of Schwann cell proliferation(GO:0010624)
1.0 3.0 GO:0060722 spongiotrophoblast cell proliferation(GO:0060720) cell proliferation involved in embryonic placenta development(GO:0060722)
1.0 3.0 GO:0002582 myeloid dendritic cell activation involved in immune response(GO:0002277) positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588)
1.0 4.0 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
1.0 3.0 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
1.0 3.9 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
1.0 11.8 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
1.0 2.9 GO:0044413 CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment(GO:0002362) negative regulation of macrophage cytokine production(GO:0010936) evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834) negative regulation of hyaluronan biosynthetic process(GO:1900126)
1.0 5.8 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
1.0 2.9 GO:0016032 viral process(GO:0016032)
1.0 5.8 GO:1904180 negative regulation of membrane depolarization(GO:1904180)
1.0 6.7 GO:0015670 carbon dioxide transport(GO:0015670)
0.9 2.8 GO:0010360 negative regulation of anion channel activity(GO:0010360)
0.9 4.7 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.9 2.8 GO:0015858 nucleoside transport(GO:0015858)
0.9 12.3 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.9 3.8 GO:0030827 negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283)
0.9 2.8 GO:0002017 regulation of blood volume by renal aldosterone(GO:0002017)
0.9 1.9 GO:0038158 granulocyte colony-stimulating factor signaling pathway(GO:0038158)
0.9 2.8 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.9 4.6 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.9 4.5 GO:0070103 regulation of interleukin-6-mediated signaling pathway(GO:0070103)
0.9 3.6 GO:1904529 regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
0.9 11.7 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.9 13.5 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.9 3.6 GO:0061386 closure of optic fissure(GO:0061386)
0.9 5.3 GO:0006216 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.9 4.5 GO:1905424 regulation of Wnt-mediated midbrain dopaminergic neuron differentiation(GO:1905424) positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation(GO:1905426)
0.9 5.2 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.9 3.5 GO:0007066 female meiosis sister chromatid cohesion(GO:0007066)
0.9 6.1 GO:0033567 DNA replication, Okazaki fragment processing(GO:0033567)
0.9 6.9 GO:1903575 cornified envelope assembly(GO:1903575)
0.9 3.5 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.8 6.8 GO:0007144 female meiosis I(GO:0007144)
0.8 2.5 GO:0046882 negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.8 13.4 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.8 4.2 GO:0044849 estrous cycle(GO:0044849)
0.8 2.5 GO:1904978 regulation of endosome organization(GO:1904978) positive regulation of endosome organization(GO:1904980)
0.8 2.4 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.8 7.3 GO:0016198 axon choice point recognition(GO:0016198)
0.8 2.4 GO:0002838 negative regulation of response to tumor cell(GO:0002835) negative regulation of immune response to tumor cell(GO:0002838)
0.8 1.6 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
0.8 1.6 GO:2000567 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.8 2.4 GO:0045896 regulation of transcription during mitotic cell cycle(GO:0045896) positive regulation of transcription during mitotic cell cycle(GO:0045897) regulation of transcription from RNA polymerase II promoter during mitotic cell cycle(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitotic cell cycle(GO:0046022)
0.8 2.3 GO:0072720 cellular response to UV-A(GO:0071492) response to dithiothreitol(GO:0072720)
0.8 4.6 GO:0071374 cellular response to parathyroid hormone stimulus(GO:0071374)
0.8 5.4 GO:0043320 natural killer cell degranulation(GO:0043320)
0.8 5.3 GO:0048102 autophagic cell death(GO:0048102)
0.8 3.0 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.8 6.8 GO:0090308 regulation of methylation-dependent chromatin silencing(GO:0090308)
0.8 2.3 GO:0060994 regulation of transcription from RNA polymerase II promoter involved in kidney development(GO:0060994)
0.7 33.0 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.7 3.0 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.7 1.5 GO:0035582 sequestering of BMP in extracellular matrix(GO:0035582)
0.7 3.6 GO:0035989 tendon development(GO:0035989)
0.7 2.9 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.7 2.9 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.7 1.4 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.7 2.1 GO:0060364 frontal suture morphogenesis(GO:0060364)
0.7 2.1 GO:0098763 mitotic cell cycle phase(GO:0098763)
0.7 2.1 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.7 2.1 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.7 2.1 GO:0034971 histone H3-R17 methylation(GO:0034971)
0.7 2.8 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.7 4.1 GO:0042891 antibiotic transport(GO:0042891)
0.7 2.1 GO:2000016 negative regulation of determination of dorsal identity(GO:2000016)
0.7 2.0 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.7 2.7 GO:0045659 negative regulation of neutrophil differentiation(GO:0045659)
0.7 2.7 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.7 2.0 GO:0060166 olfactory pit development(GO:0060166)
0.7 5.9 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.7 7.8 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.7 3.3 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.7 5.2 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.6 0.6 GO:0031086 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.6 2.6 GO:0040030 regulation of molecular function, epigenetic(GO:0040030)
0.6 2.6 GO:0061743 motor learning(GO:0061743)
0.6 1.9 GO:0038183 bile acid signaling pathway(GO:0038183)
0.6 7.0 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.6 2.5 GO:0050904 diapedesis(GO:0050904)
0.6 8.7 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.6 0.6 GO:0099552 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.6 1.8 GO:0045404 positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.6 6.7 GO:0071294 cellular response to zinc ion(GO:0071294)
0.6 1.8 GO:0019659 fermentation(GO:0006113) L(+)-lactate biosynthetic process from pyruvate(GO:0019246) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.6 6.1 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.6 3.1 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.6 4.3 GO:0042148 strand invasion(GO:0042148)
0.6 5.5 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.6 5.9 GO:1900086 positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086)
0.6 2.4 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
0.6 1.8 GO:0089700 protein kinase D signaling(GO:0089700)
0.6 1.2 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.6 1.8 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.6 2.3 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.6 3.5 GO:1903755 regulation of SUMO transferase activity(GO:1903182) positive regulation of SUMO transferase activity(GO:1903755)
0.6 1.7 GO:1905719 protein localization to perinuclear region of cytoplasm(GO:1905719)
0.6 0.6 GO:0072244 metanephric glomerular epithelium development(GO:0072244)
0.6 2.8 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.6 2.8 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.6 1.7 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.5 1.6 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.5 0.5 GO:0099640 dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964) axo-dendritic protein transport(GO:0099640)
0.5 1.6 GO:0061792 secretory granule maturation(GO:0061792)
0.5 3.8 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.5 1.6 GO:0006742 NADP catabolic process(GO:0006742)
0.5 11.2 GO:0051693 actin filament capping(GO:0051693)
0.5 1.6 GO:2000474 regulation of opioid receptor signaling pathway(GO:2000474)
0.5 2.7 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.5 4.2 GO:0071361 cellular response to ethanol(GO:0071361)
0.5 3.1 GO:2000648 positive regulation of stem cell proliferation(GO:2000648)
0.5 5.8 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.5 2.6 GO:1905522 negative regulation of macrophage chemotaxis(GO:0010760) negative regulation of macrophage migration(GO:1905522)
0.5 3.1 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.5 8.8 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.5 6.1 GO:0034242 negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.5 1.0 GO:0060137 maternal process involved in parturition(GO:0060137)
0.5 6.0 GO:0035646 endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
0.5 2.5 GO:0035633 maintenance of permeability of blood-brain barrier(GO:0035633)
0.5 5.5 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.5 2.0 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.5 1.5 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.5 6.9 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.5 2.0 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.5 8.7 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.5 4.4 GO:0043249 erythrocyte maturation(GO:0043249)
0.5 1.9 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.5 1.4 GO:0033082 regulation of extrathymic T cell differentiation(GO:0033082)
0.5 2.3 GO:0021592 fourth ventricle development(GO:0021592) initiation of neural tube closure(GO:0021993)
0.5 0.5 GO:1905602 positive regulation of receptor-mediated endocytosis involved in cholesterol transport(GO:1905602)
0.5 1.4 GO:0070844 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.5 2.3 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.5 1.4 GO:0051316 attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation(GO:0051316)
0.5 1.4 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.5 1.8 GO:0051643 endoplasmic reticulum localization(GO:0051643)
0.4 1.8 GO:0061589 calcium activated phosphatidylserine scrambling(GO:0061589)
0.4 1.8 GO:0070889 platelet alpha granule organization(GO:0070889)
0.4 1.8 GO:1900133 regulation of renin secretion into blood stream(GO:1900133)
0.4 2.2 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.4 0.9 GO:2001015 negative regulation of skeletal muscle cell differentiation(GO:2001015)
0.4 13.0 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.4 3.0 GO:0000042 protein targeting to Golgi(GO:0000042)
0.4 2.6 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.4 2.6 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.4 2.6 GO:0051790 acetate metabolic process(GO:0006083) short-chain fatty acid biosynthetic process(GO:0051790)
0.4 9.7 GO:0014823 response to activity(GO:0014823)
0.4 2.5 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.4 4.6 GO:0030853 negative regulation of granulocyte differentiation(GO:0030853)
0.4 2.1 GO:1905342 regulation of protein localization to kinetochore(GO:1905340) positive regulation of protein localization to kinetochore(GO:1905342)
0.4 2.9 GO:1902033 regulation of hematopoietic stem cell proliferation(GO:1902033)
0.4 2.5 GO:0002317 plasma cell differentiation(GO:0002317)
0.4 8.2 GO:0001675 acrosome assembly(GO:0001675)
0.4 3.3 GO:0000052 citrulline metabolic process(GO:0000052)
0.4 0.4 GO:1902969 mitotic DNA replication(GO:1902969)
0.4 1.6 GO:0002901 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.4 0.8 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.4 1.2 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cytosol(GO:1902656)
0.4 1.2 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.4 2.0 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.4 4.0 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.4 1.6 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.4 1.2 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.4 2.4 GO:0061644 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641) protein localization to CENP-A containing chromatin(GO:0061644)
0.4 0.8 GO:0032741 positive regulation of interleukin-18 production(GO:0032741)
0.4 1.2 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.4 2.7 GO:0006868 glutamine transport(GO:0006868)
0.4 10.7 GO:0045830 positive regulation of isotype switching(GO:0045830)
0.4 4.2 GO:0000733 DNA strand renaturation(GO:0000733)
0.4 1.1 GO:2000556 T-helper 1 cell cytokine production(GO:0035744) regulation of T-helper 1 cell cytokine production(GO:2000554) positive regulation of T-helper 1 cell cytokine production(GO:2000556)
0.4 3.8 GO:0030007 cellular potassium ion homeostasis(GO:0030007)
0.4 2.6 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.4 1.1 GO:0006550 isoleucine catabolic process(GO:0006550)
0.4 3.4 GO:0002035 brain renin-angiotensin system(GO:0002035)
0.4 2.2 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.4 2.2 GO:0006561 proline biosynthetic process(GO:0006561)
0.4 2.6 GO:0070458 detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
0.4 1.8 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
0.4 4.8 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.4 2.9 GO:1905516 positive regulation of fertilization(GO:1905516) positive regulation of acrosome reaction(GO:2000344)
0.4 0.7 GO:0009794 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.4 2.5 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.4 0.4 GO:0006713 glucocorticoid catabolic process(GO:0006713)
0.4 1.4 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.4 1.4 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.4 7.8 GO:0008340 determination of adult lifespan(GO:0008340)
0.4 4.6 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.4 2.8 GO:0033085 negative regulation of T cell differentiation in thymus(GO:0033085)
0.4 6.0 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.4 1.1 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.3 1.0 GO:1900365 negative regulation of cytoplasmic translational elongation(GO:1900248) positive regulation of mRNA polyadenylation(GO:1900365)
0.3 1.0 GO:0072737 response to diamide(GO:0072737) cellular response to diamide(GO:0072738)
0.3 1.7 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.3 1.0 GO:0001805 antibody-dependent cellular cytotoxicity(GO:0001788) type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805)
0.3 1.4 GO:0060265 positive regulation of respiratory burst involved in inflammatory response(GO:0060265)
0.3 1.4 GO:1902340 telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340)
0.3 2.8 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.3 1.7 GO:0051697 protein delipidation(GO:0051697)
0.3 0.7 GO:1905863 invadopodium organization(GO:1905863)
0.3 1.0 GO:0003356 regulation of cilium beat frequency(GO:0003356)
0.3 2.7 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.3 2.7 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.3 1.3 GO:0019673 GDP-mannose metabolic process(GO:0019673)
0.3 2.3 GO:0070572 positive regulation of neuron projection regeneration(GO:0070572)
0.3 3.3 GO:0085020 protein K6-linked ubiquitination(GO:0085020)
0.3 1.7 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.3 1.7 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.3 5.0 GO:0036159 inner dynein arm assembly(GO:0036159)
0.3 3.0 GO:0120009 intermembrane lipid transfer(GO:0120009)
0.3 1.6 GO:0044805 late nucleophagy(GO:0044805)
0.3 1.6 GO:0032226 positive regulation of synaptic transmission, dopaminergic(GO:0032226)
0.3 1.0 GO:0040019 positive regulation of embryonic development(GO:0040019)
0.3 2.0 GO:0002536 respiratory burst involved in inflammatory response(GO:0002536)
0.3 3.6 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.3 5.5 GO:0034508 centromere complex assembly(GO:0034508)
0.3 1.0 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.3 1.3 GO:2001183 negative regulation of interleukin-12 secretion(GO:2001183)
0.3 0.9 GO:1902990 mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.3 4.7 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.3 4.4 GO:0060046 regulation of acrosome reaction(GO:0060046)
0.3 0.9 GO:0072061 inner medullary collecting duct development(GO:0072061)
0.3 2.1 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.3 3.6 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.3 2.4 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.3 2.7 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.3 4.5 GO:0090280 positive regulation of calcium ion import(GO:0090280)
0.3 0.3 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
0.3 14.1 GO:0006270 DNA replication initiation(GO:0006270)
0.3 13.5 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.3 0.9 GO:0031268 pseudopodium organization(GO:0031268)
0.3 1.2 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.3 0.6 GO:0010815 bradykinin catabolic process(GO:0010815)
0.3 0.6 GO:0061357 Wnt protein secretion(GO:0061355) regulation of Wnt protein secretion(GO:0061356) positive regulation of Wnt protein secretion(GO:0061357)
0.3 2.6 GO:0048484 enteric nervous system development(GO:0048484)
0.3 2.6 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.3 0.3 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.3 1.4 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.3 13.9 GO:0003009 skeletal muscle contraction(GO:0003009)
0.3 5.1 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.3 0.8 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.3 8.4 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.3 1.9 GO:0043313 regulation of neutrophil degranulation(GO:0043313) regulation of neutrophil activation(GO:1902563)
0.3 3.6 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.3 1.4 GO:0015810 aspartate transport(GO:0015810)
0.3 1.1 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.3 2.2 GO:0097107 postsynaptic density assembly(GO:0097107) postsynaptic specialization assembly(GO:0098698)
0.3 1.9 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.3 1.1 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.3 4.3 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.3 0.3 GO:0045918 negative regulation of cytolysis(GO:0045918)
0.3 0.8 GO:0019043 establishment of viral latency(GO:0019043)
0.3 0.8 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.3 0.8 GO:1901608 regulation of vesicle transport along microtubule(GO:1901608)
0.3 1.6 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.3 0.8 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.3 2.6 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.3 1.3 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.3 8.1 GO:0048268 clathrin coat assembly(GO:0048268)
0.3 1.0 GO:0015786 UDP-glucose transport(GO:0015786)
0.3 3.1 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.3 1.6 GO:0008355 olfactory learning(GO:0008355)
0.3 2.3 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.3 1.0 GO:0046898 response to cycloheximide(GO:0046898)
0.3 0.8 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.3 3.6 GO:0046036 CTP biosynthetic process(GO:0006241) pyrimidine ribonucleoside triphosphate biosynthetic process(GO:0009209) CTP metabolic process(GO:0046036)
0.3 0.8 GO:1903490 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.3 0.8 GO:0036090 cleavage furrow ingression(GO:0036090)
0.3 4.8 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.3 9.6 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.3 2.8 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.3 0.8 GO:0106004 tRNA (guanine-N7)-methylation(GO:0106004)
0.2 11.0 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.2 3.7 GO:0044458 motile cilium assembly(GO:0044458)
0.2 2.7 GO:0001956 positive regulation of neurotransmitter secretion(GO:0001956)
0.2 0.7 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.2 1.4 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.2 6.7 GO:0060216 definitive hemopoiesis(GO:0060216)
0.2 2.6 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
0.2 1.9 GO:0010764 negative regulation of fibroblast migration(GO:0010764)
0.2 2.8 GO:0021860 pyramidal neuron development(GO:0021860)
0.2 3.7 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.2 1.4 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.2 13.7 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.2 1.2 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.2 1.2 GO:2000172 regulation of branching morphogenesis of a nerve(GO:2000172)
0.2 0.7 GO:1901994 negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.2 1.8 GO:0071493 cellular response to UV-B(GO:0071493)
0.2 0.2 GO:0097168 mesenchymal stem cell proliferation(GO:0097168) regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.2 2.1 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.2 1.6 GO:0035898 parathyroid hormone secretion(GO:0035898)
0.2 1.6 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.2 2.0 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.2 0.4 GO:0072053 renal inner medulla development(GO:0072053)
0.2 0.7 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.2 0.7 GO:0043385 mycotoxin metabolic process(GO:0043385) aflatoxin metabolic process(GO:0046222) organic heteropentacyclic compound metabolic process(GO:1901376)
0.2 2.7 GO:2000394 positive regulation of lamellipodium morphogenesis(GO:2000394)
0.2 0.4 GO:0014047 glutamate secretion(GO:0014047)
0.2 1.3 GO:0098838 reduced folate transmembrane transport(GO:0098838)
0.2 1.1 GO:0071280 cellular response to copper ion(GO:0071280)
0.2 0.6 GO:0071351 interleukin-18-mediated signaling pathway(GO:0035655) cellular response to interleukin-18(GO:0071351)
0.2 1.1 GO:0035617 stress granule disassembly(GO:0035617)
0.2 0.6 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.2 2.7 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.2 0.6 GO:0009233 menaquinone metabolic process(GO:0009233)
0.2 0.6 GO:0090063 regulation of microtubule nucleation(GO:0010968) positive regulation of microtubule nucleation(GO:0090063)
0.2 0.8 GO:0021764 amygdala development(GO:0021764)
0.2 1.5 GO:0031297 replication fork processing(GO:0031297)
0.2 0.2 GO:0003097 renal water transport(GO:0003097)
0.2 3.1 GO:0031065 positive regulation of histone deacetylation(GO:0031065)
0.2 0.4 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.2 0.2 GO:0032095 regulation of response to food(GO:0032095) negative regulation of response to food(GO:0032096) regulation of appetite(GO:0032098) negative regulation of appetite(GO:0032099) negative regulation of response to extracellular stimulus(GO:0032105) negative regulation of response to nutrient levels(GO:0032108)
0.2 2.2 GO:0036158 outer dynein arm assembly(GO:0036158)
0.2 0.8 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
0.2 3.6 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211)
0.2 0.8 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.2 1.0 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.2 1.2 GO:0050917 sensory perception of umami taste(GO:0050917)
0.2 0.4 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.2 1.8 GO:0006013 mannose metabolic process(GO:0006013)
0.2 1.2 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.2 0.6 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.2 6.6 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.2 2.1 GO:0060056 mammary gland involution(GO:0060056)
0.2 3.3 GO:0046653 tetrahydrofolate metabolic process(GO:0046653)
0.2 8.8 GO:1904031 positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.2 4.4 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.2 1.5 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.2 0.4 GO:0019042 viral latency(GO:0019042)
0.2 0.4 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.2 0.6 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.2 5.4 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.2 1.7 GO:0045048 protein insertion into ER membrane(GO:0045048)
0.2 1.1 GO:0022417 protein maturation by protein folding(GO:0022417)
0.2 1.5 GO:0042167 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.2 1.7 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.2 7.1 GO:2000008 regulation of protein localization to cell surface(GO:2000008)
0.2 8.6 GO:0008347 glial cell migration(GO:0008347)
0.2 0.7 GO:1903028 regulation of opsonization(GO:1903027) positive regulation of opsonization(GO:1903028)
0.2 2.0 GO:0106030 axonal fasciculation(GO:0007413) neuron projection fasciculation(GO:0106030)
0.2 0.9 GO:0009597 detection of virus(GO:0009597)
0.2 0.4 GO:0001743 optic placode formation(GO:0001743)
0.2 0.5 GO:1902805 positive regulation of synaptic vesicle transport(GO:1902805) positive regulation of synaptic vesicle recycling(GO:1903423)
0.2 1.6 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.2 1.1 GO:1905651 regulation of artery morphogenesis(GO:1905651)
0.2 0.5 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878) positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.2 1.8 GO:0033363 secretory granule organization(GO:0033363)
0.2 1.2 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.2 1.1 GO:0090527 actin filament reorganization(GO:0090527)
0.2 1.2 GO:0032808 lacrimal gland development(GO:0032808)
0.2 1.9 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.2 0.7 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.2 0.7 GO:1905077 negative regulation of interleukin-17 secretion(GO:1905077)
0.2 0.9 GO:0071918 urea transmembrane transport(GO:0071918)
0.2 2.7 GO:0072010 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.2 0.3 GO:0051930 regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931)
0.2 1.9 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.2 2.2 GO:0046085 adenosine metabolic process(GO:0046085)
0.2 1.5 GO:0015866 ADP transport(GO:0015866)
0.2 1.0 GO:0045987 positive regulation of smooth muscle contraction(GO:0045987)
0.2 0.7 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.2 0.3 GO:0021506 anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)
0.2 1.0 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.2 2.4 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.2 0.6 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.2 2.7 GO:0005980 glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.2 1.1 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.2 0.5 GO:0042339 keratan sulfate metabolic process(GO:0042339)
0.2 0.2 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.2 2.7 GO:2000369 regulation of clathrin-dependent endocytosis(GO:2000369)
0.2 0.9 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.2 2.2 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.2 0.6 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.2 0.8 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465)
0.2 2.0 GO:0006999 nuclear pore organization(GO:0006999)
0.2 8.7 GO:0070527 platelet aggregation(GO:0070527)
0.2 0.6 GO:0009814 defense response, incompatible interaction(GO:0009814)
0.2 0.5 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.2 2.4 GO:0070208 protein heterotrimerization(GO:0070208)
0.2 0.5 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.1 3.1 GO:0090022 regulation of neutrophil chemotaxis(GO:0090022)
0.1 0.6 GO:0050857 positive regulation of antigen receptor-mediated signaling pathway(GO:0050857)
0.1 1.8 GO:0061339 establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.1 0.9 GO:0051284 negative regulation of release of sequestered calcium ion into cytosol(GO:0051280) positive regulation of sequestering of calcium ion(GO:0051284)
0.1 1.5 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 5.9 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 0.7 GO:1902713 regulation of interferon-gamma secretion(GO:1902713) positive regulation of interferon-gamma secretion(GO:1902715)
0.1 2.0 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.1 1.1 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.1 20.5 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.1 0.7 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 0.7 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.1 0.8 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.1 0.7 GO:0050729 positive regulation of inflammatory response(GO:0050729)
0.1 1.5 GO:0035855 megakaryocyte development(GO:0035855)
0.1 0.7 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
0.1 1.1 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 1.7 GO:0051205 protein insertion into membrane(GO:0051205)
0.1 3.6 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336)
0.1 1.7 GO:0043045 DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.1 1.0 GO:0050884 neuromuscular process controlling posture(GO:0050884)
0.1 0.5 GO:1902525 regulation of protein monoubiquitination(GO:1902525)
0.1 2.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 0.4 GO:1902277 negative regulation of pancreatic amylase secretion(GO:1902277)
0.1 1.3 GO:0046641 positive regulation of alpha-beta T cell proliferation(GO:0046641)
0.1 0.5 GO:0072718 response to cisplatin(GO:0072718)
0.1 1.5 GO:0007224 smoothened signaling pathway(GO:0007224)
0.1 0.3 GO:0032202 telomere assembly(GO:0032202)
0.1 0.8 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.1 1.1 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.1 1.5 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.1 2.0 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.1 1.7 GO:0043486 histone exchange(GO:0043486)
0.1 0.7 GO:0060706 cell differentiation involved in embryonic placenta development(GO:0060706)
0.1 1.0 GO:0014832 urinary bladder smooth muscle contraction(GO:0014832)
0.1 0.2 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.1 6.7 GO:0046579 positive regulation of Ras protein signal transduction(GO:0046579)
0.1 2.9 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.1 0.8 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.1 0.5 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.1 0.8 GO:0043416 regulation of skeletal muscle tissue regeneration(GO:0043416)
0.1 1.9 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.1 0.9 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.1 0.9 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.1 1.1 GO:0097500 receptor localization to non-motile cilium(GO:0097500)
0.1 1.0 GO:0060974 neural crest cell migration involved in heart formation(GO:0003147) cell migration involved in heart formation(GO:0060974) anterior neural tube closure(GO:0061713) cellular response to folic acid(GO:0071231)
0.1 3.5 GO:0009409 response to cold(GO:0009409)
0.1 0.6 GO:0098909 regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.1 2.3 GO:0045954 positive regulation of natural killer cell mediated immunity(GO:0002717) positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.1 1.2 GO:1904867 regulation of establishment of protein localization to telomere(GO:0070203) protein localization to nuclear body(GO:1903405) positive regulation of protein localization to chromosome, telomeric region(GO:1904816) positive regulation of establishment of protein localization to telomere(GO:1904851) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173)
0.1 0.6 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.1 2.4 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.1 0.2 GO:1905664 regulation of calcium ion import across plasma membrane(GO:1905664)
0.1 3.0 GO:0031424 keratinization(GO:0031424)
0.1 0.9 GO:0007625 grooming behavior(GO:0007625)
0.1 0.3 GO:0009106 lipoate metabolic process(GO:0009106)
0.1 0.4 GO:0006014 D-ribose metabolic process(GO:0006014)
0.1 2.1 GO:0002021 response to dietary excess(GO:0002021)
0.1 0.3 GO:0051866 general adaptation syndrome(GO:0051866)
0.1 9.3 GO:0098869 cellular oxidant detoxification(GO:0098869)
0.1 0.5 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.1 0.5 GO:0043201 response to leucine(GO:0043201) cellular response to leucine(GO:0071233)
0.1 1.1 GO:0051220 cytoplasmic sequestering of protein(GO:0051220)
0.1 0.5 GO:0048715 negative regulation of oligodendrocyte differentiation(GO:0048715)
0.1 3.5 GO:0006284 base-excision repair(GO:0006284)
0.1 0.6 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.1 0.6 GO:0031507 heterochromatin assembly(GO:0031507)
0.1 0.7 GO:0070831 basement membrane assembly(GO:0070831)
0.1 0.6 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891)
0.1 0.3 GO:0021933 radial glia guided migration of cerebellar granule cell(GO:0021933)
0.1 0.7 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.1 0.3 GO:0060279 positive regulation of ovulation(GO:0060279)
0.1 0.5 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.1 1.1 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.1 0.8 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.1 0.8 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.1 1.8 GO:0034587 piRNA metabolic process(GO:0034587)
0.1 0.3 GO:0086053 AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.1 0.4 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.1 0.3 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.1 3.1 GO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200)
0.1 0.8 GO:1900181 negative regulation of protein localization to nucleus(GO:1900181)
0.1 1.8 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 1.2 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.1 1.9 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.1 0.4 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.1 1.8 GO:0001964 startle response(GO:0001964)
0.1 1.7 GO:0035640 exploration behavior(GO:0035640)
0.1 0.9 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.1 0.2 GO:2001286 regulation of caveolin-mediated endocytosis(GO:2001286)
0.1 1.5 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.1 1.5 GO:0010667 negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.1 0.5 GO:0042481 regulation of odontogenesis(GO:0042481)
0.1 1.1 GO:0002115 store-operated calcium entry(GO:0002115)
0.1 1.7 GO:0098534 centriole replication(GO:0007099) centriole assembly(GO:0098534)
0.1 0.7 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.1 0.2 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.1 0.1 GO:0060084 micturition(GO:0060073) synaptic transmission involved in micturition(GO:0060084)
0.1 1.3 GO:0086016 AV node cell action potential(GO:0086016) AV node cell to bundle of His cell signaling(GO:0086027) AV node cell to bundle of His cell communication(GO:0086067)
0.1 1.0 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.1 0.4 GO:0034088 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.1 1.2 GO:0035493 SNARE complex assembly(GO:0035493)
0.1 0.2 GO:0006589 octopamine biosynthetic process(GO:0006589) octopamine metabolic process(GO:0046333)
0.1 0.4 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 1.2 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.1 0.4 GO:2000210 positive regulation of anoikis(GO:2000210)
0.1 1.5 GO:0006308 DNA catabolic process(GO:0006308)
0.1 0.4 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 1.1 GO:0017121 phospholipid scrambling(GO:0017121)
0.1 0.3 GO:0035927 RNA import into mitochondrion(GO:0035927)
0.1 1.2 GO:0048255 mRNA stabilization(GO:0048255)
0.1 0.6 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 0.1 GO:0080144 amino acid homeostasis(GO:0080144)
0.1 0.3 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.1 0.3 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.1 3.9 GO:0051865 protein autoubiquitination(GO:0051865)
0.1 1.1 GO:0032456 endocytic recycling(GO:0032456)
0.1 1.1 GO:0033622 integrin activation(GO:0033622)
0.1 0.3 GO:0015960 diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966)
0.1 0.5 GO:1902856 negative regulation of non-motile cilium assembly(GO:1902856)
0.1 1.6 GO:0030574 collagen catabolic process(GO:0030574)
0.1 1.2 GO:0050691 regulation of defense response to virus by host(GO:0050691)
0.1 0.5 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.1 0.6 GO:0035330 regulation of hippo signaling(GO:0035330)
0.1 0.7 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.1 2.2 GO:0000281 mitotic cytokinesis(GO:0000281)
0.1 0.4 GO:1990928 response to amino acid starvation(GO:1990928)
0.1 1.7 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.1 0.6 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.1 0.4 GO:0043267 negative regulation of potassium ion transport(GO:0043267)
0.1 0.2 GO:0035280 miRNA loading onto RISC involved in gene silencing by miRNA(GO:0035280)
0.1 0.6 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.1 1.7 GO:0000154 rRNA modification(GO:0000154)
0.1 0.1 GO:0002268 follicular dendritic cell activation(GO:0002266) follicular dendritic cell differentiation(GO:0002268)
0.1 3.4 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.1 1.8 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.1 0.3 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.1 1.0 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.1 1.5 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.1 0.7 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.1 1.0 GO:0030252 growth hormone secretion(GO:0030252)
0.1 1.1 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.1 0.3 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.1 0.2 GO:0015803 branched-chain amino acid transport(GO:0015803)
0.1 0.4 GO:0001778 plasma membrane repair(GO:0001778)
0.1 1.7 GO:0030593 neutrophil chemotaxis(GO:0030593)
0.1 0.2 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.1 1.0 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.1 0.7 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.1 0.4 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.1 1.4 GO:0007032 endosome organization(GO:0007032)
0.1 0.4 GO:0071763 nuclear membrane organization(GO:0071763)
0.1 0.8 GO:0036065 fucosylation(GO:0036065)
0.1 1.3 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 1.0 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.0 0.1 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.2 GO:1902603 carnitine transmembrane transport(GO:1902603)
0.0 0.5 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.5 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.9 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.0 0.1 GO:0048733 sebaceous gland development(GO:0048733)
0.0 1.2 GO:0002062 chondrocyte differentiation(GO:0002062)
0.0 0.4 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 0.2 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.0 0.7 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0 0.6 GO:0021535 cell migration in hindbrain(GO:0021535)
0.0 0.1 GO:0002352 B cell negative selection(GO:0002352)
0.0 1.0 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.0 1.4 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.0 GO:0044803 multi-organism membrane organization(GO:0044803)
0.0 0.3 GO:0032464 regulation of protein homooligomerization(GO:0032462) positive regulation of protein homooligomerization(GO:0032464)
0.0 0.9 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.1 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.2 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 0.1 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.0 0.3 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.2 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.1 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 1.2 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.1 GO:1905049 negative regulation of metallopeptidase activity(GO:1905049)
0.0 0.7 GO:0051444 negative regulation of ubiquitin-protein transferase activity(GO:0051444)
0.0 0.3 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 0.4 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.0 0.1 GO:2000078 positive regulation of type B pancreatic cell development(GO:2000078)
0.0 0.8 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.0 0.6 GO:1903038 negative regulation of leukocyte cell-cell adhesion(GO:1903038)
0.0 0.8 GO:1903146 regulation of autophagy of mitochondrion(GO:1903146)
0.0 0.7 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.0 0.2 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.6 GO:0048286 lung alveolus development(GO:0048286)
0.0 0.6 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.1 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.0 0.8 GO:0006693 prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.0 0.2 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.2 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.3 GO:0048169 regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.0 0.6 GO:0007617 mating behavior(GO:0007617)
0.0 0.1 GO:2001012 mesenchymal cell differentiation involved in kidney development(GO:0072161) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0 0.2 GO:0097646 dimeric G-protein coupled receptor signaling pathway(GO:0038042) calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.2 GO:0055075 potassium ion homeostasis(GO:0055075)
0.0 0.3 GO:0001991 regulation of systemic arterial blood pressure by circulatory renin-angiotensin(GO:0001991)
0.0 0.1 GO:0033189 response to vitamin A(GO:0033189)
0.0 0.3 GO:1902916 positive regulation of protein polyubiquitination(GO:1902916)
0.0 0.1 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.0 0.6 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.3 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.8 GO:0009712 catecholamine metabolic process(GO:0006584) catechol-containing compound metabolic process(GO:0009712)
0.0 2.2 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.1 GO:0009624 response to nematode(GO:0009624)
0.0 0.3 GO:1901096 regulation of autophagosome maturation(GO:1901096)
0.0 0.1 GO:0030728 ovulation(GO:0030728)
0.0 0.3 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.0 1.2 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.0 0.2 GO:0060149 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
0.0 0.4 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.4 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.1 GO:0046103 inosine biosynthetic process(GO:0046103)
0.0 0.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.4 GO:0002437 inflammatory response to antigenic stimulus(GO:0002437)
0.0 0.1 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.0 0.1 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.8 GO:0042274 ribosomal small subunit biogenesis(GO:0042274)
0.0 0.2 GO:0031498 chromatin disassembly(GO:0031498)
0.0 0.8 GO:0021954 central nervous system neuron development(GO:0021954)
0.0 0.1 GO:0030576 Cajal body organization(GO:0030576)
0.0 0.4 GO:2001240 negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.3 GO:0016998 cell wall macromolecule catabolic process(GO:0016998) cell wall macromolecule metabolic process(GO:0044036) cell wall organization or biogenesis(GO:0071554)
0.0 0.7 GO:0048747 muscle fiber development(GO:0048747)
0.0 1.0 GO:0014065 phosphatidylinositol 3-kinase signaling(GO:0014065)
0.0 0.1 GO:0070914 UV-damage excision repair(GO:0070914) UV-damage excision repair, DNA incision(GO:1990731)
0.0 0.1 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of sulfur metabolic process(GO:0051176) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.1 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.0 0.1 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.0 0.1 GO:0048254 snoRNA localization(GO:0048254)
0.0 0.5 GO:0051225 spindle assembly(GO:0051225)
0.0 0.5 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.1 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 1.1 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.1 GO:2000311 regulation of AMPA receptor activity(GO:2000311)
0.0 0.1 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.0 0.4 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 0.3 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.3 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0 0.2 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.0 0.8 GO:0008585 female gonad development(GO:0008585)
0.0 0.8 GO:1902017 regulation of cilium assembly(GO:1902017)
0.0 0.4 GO:0006400 tRNA modification(GO:0006400)
0.0 0.1 GO:0051923 sulfation(GO:0051923)
0.0 0.4 GO:0071479 cellular response to ionizing radiation(GO:0071479)
0.0 0.0 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.0 0.1 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.3 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.0 0.1 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.0 0.3 GO:0032332 positive regulation of chondrocyte differentiation(GO:0032332)
0.0 0.3 GO:0008542 visual learning(GO:0008542)
0.0 0.1 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 1.6 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
5.9 23.6 GO:0070442 integrin alphaIIb-beta3 complex(GO:0070442)
5.2 41.7 GO:0005833 hemoglobin complex(GO:0005833)
5.0 19.9 GO:0031095 platelet dense tubular network membrane(GO:0031095)
4.6 13.9 GO:0033193 Lsd1/2 complex(GO:0033193)
4.2 20.8 GO:0031523 Myb complex(GO:0031523)
3.8 11.5 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
3.8 15.1 GO:0044218 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
3.0 9.0 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
2.8 42.2 GO:0042581 specific granule(GO:0042581)
2.5 25.4 GO:0008290 F-actin capping protein complex(GO:0008290)
2.2 24.1 GO:0033093 Weibel-Palade body(GO:0033093)
1.7 6.9 GO:0097450 astrocyte end-foot(GO:0097450)
1.7 23.1 GO:0090543 Flemming body(GO:0090543)
1.6 4.8 GO:0034774 secretory granule lumen(GO:0034774) cytoplasmic vesicle lumen(GO:0060205)
1.4 21.8 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
1.3 3.8 GO:1990423 RZZ complex(GO:1990423)
1.1 3.4 GO:0042583 chromaffin granule(GO:0042583)
1.1 20.2 GO:0005861 troponin complex(GO:0005861)
1.1 7.9 GO:0019815 B cell receptor complex(GO:0019815)
1.1 6.6 GO:0031262 Ndc80 complex(GO:0031262)
1.1 21.4 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
1.0 10.2 GO:0044326 dendritic spine neck(GO:0044326)
0.9 2.8 GO:0046691 intracellular canaliculus(GO:0046691)
0.9 5.5 GO:1990075 periciliary membrane compartment(GO:1990075)
0.9 3.6 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.9 9.9 GO:0071439 clathrin complex(GO:0071439)
0.9 7.0 GO:0005664 nuclear origin of replication recognition complex(GO:0005664)
0.9 6.0 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.8 2.5 GO:0043512 inhibin-betaglycan-ActRII complex(GO:0034673) inhibin A complex(GO:0043512)
0.8 3.3 GO:0000802 transverse filament(GO:0000802)
0.8 3.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.8 2.3 GO:0005940 septin ring(GO:0005940)
0.8 2.3 GO:1990257 piccolo-bassoon transport vesicle(GO:1990257)
0.8 3.0 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.7 10.3 GO:0097542 ciliary tip(GO:0097542)
0.7 2.2 GO:0005588 collagen type V trimer(GO:0005588)
0.7 2.1 GO:0035101 FACT complex(GO:0035101)
0.7 2.8 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.7 0.7 GO:0005607 laminin-2 complex(GO:0005607)
0.7 10.3 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.7 9.5 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.7 2.6 GO:0014802 terminal cisterna(GO:0014802)
0.7 5.9 GO:0097427 microtubule bundle(GO:0097427)
0.6 2.6 GO:0045160 myosin I complex(GO:0045160)
0.6 11.2 GO:0005652 nuclear lamina(GO:0005652)
0.6 1.8 GO:0042642 actomyosin, myosin complex part(GO:0042642)
0.6 3.5 GO:1990356 sumoylated E2 ligase complex(GO:1990356)
0.6 6.4 GO:0032584 growth cone membrane(GO:0032584)
0.6 2.3 GO:0120001 apical plasma membrane urothelial plaque(GO:0120001)
0.6 3.3 GO:0071547 piP-body(GO:0071547)
0.6 9.4 GO:0001527 microfibril(GO:0001527)
0.6 3.3 GO:0070531 BRCA1-A complex(GO:0070531)
0.6 16.0 GO:0001891 phagocytic cup(GO:0001891)
0.5 9.7 GO:0035686 sperm fibrous sheath(GO:0035686)
0.5 6.3 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.5 1.5 GO:0071920 cleavage body(GO:0071920)
0.5 2.6 GO:0044301 climbing fiber(GO:0044301)
0.5 2.0 GO:0005594 collagen type IX trimer(GO:0005594)
0.5 10.9 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.5 9.9 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.5 12.0 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.5 8.6 GO:0030061 mitochondrial crista(GO:0030061)
0.5 36.1 GO:0005844 polysome(GO:0005844)
0.5 4.2 GO:0000796 condensin complex(GO:0000796)
0.5 2.3 GO:0044611 nuclear pore inner ring(GO:0044611)
0.4 1.3 GO:0036284 tubulobulbar complex(GO:0036284)
0.4 25.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834) GTPase complex(GO:1905360)
0.4 5.7 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.4 2.1 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.4 3.3 GO:1990357 terminal web(GO:1990357)
0.4 3.6 GO:0016600 flotillin complex(GO:0016600)
0.4 1.2 GO:0071007 U2-type catalytic step 2 spliceosome(GO:0071007)
0.4 2.3 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.4 8.7 GO:0043198 dendritic shaft(GO:0043198)
0.4 1.1 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.4 2.6 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.4 1.8 GO:1990769 proximal neuron projection(GO:1990769)
0.4 3.6 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.4 2.2 GO:1990393 3M complex(GO:1990393)
0.4 1.1 GO:0043259 laminin-10 complex(GO:0043259)
0.4 1.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.4 2.5 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.4 3.9 GO:0043020 NADPH oxidase complex(GO:0043020)
0.4 1.4 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.4 7.4 GO:0031527 filopodium membrane(GO:0031527)
0.4 3.5 GO:0031080 nuclear pore outer ring(GO:0031080)
0.3 1.4 GO:0035976 transcription factor AP-1 complex(GO:0035976)
0.3 4.1 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.3 4.7 GO:0043083 synaptic cleft(GO:0043083)
0.3 7.1 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.3 2.0 GO:0042588 zymogen granule(GO:0042588)
0.3 1.0 GO:0031258 lamellipodium membrane(GO:0031258)
0.3 1.9 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.3 3.0 GO:0043034 costamere(GO:0043034)
0.3 2.7 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.3 1.5 GO:0070826 paraferritin complex(GO:0070826)
0.3 0.6 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.3 4.4 GO:0001673 male germ cell nucleus(GO:0001673)
0.3 1.2 GO:0090537 CERF complex(GO:0090537)
0.3 1.4 GO:0030314 junctional membrane complex(GO:0030314)
0.3 2.8 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.3 1.7 GO:0005927 muscle tendon junction(GO:0005927)
0.3 1.9 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.3 0.8 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.3 9.5 GO:0000788 nuclear nucleosome(GO:0000788)
0.3 1.6 GO:0043219 lateral loop(GO:0043219)
0.3 19.7 GO:0005657 replication fork(GO:0005657)
0.3 1.3 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.3 4.2 GO:0036038 MKS complex(GO:0036038)
0.3 4.9 GO:0042599 lamellar body(GO:0042599)
0.3 0.8 GO:0030905 retromer, tubulation complex(GO:0030905)
0.3 1.3 GO:0097513 myosin II filament(GO:0097513)
0.3 4.1 GO:0097470 ribbon synapse(GO:0097470) synaptic ribbon(GO:0098681)
0.2 6.0 GO:0001741 XY body(GO:0001741)
0.2 2.5 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.2 5.7 GO:0071565 nBAF complex(GO:0071565)
0.2 9.1 GO:0055038 recycling endosome membrane(GO:0055038)
0.2 1.5 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.2 2.2 GO:0097512 cardiac myofibril(GO:0097512)
0.2 2.4 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.2 26.9 GO:0017053 transcriptional repressor complex(GO:0017053)
0.2 5.0 GO:0035253 ciliary rootlet(GO:0035253)
0.2 12.1 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.2 0.7 GO:0044299 C-fiber(GO:0044299)
0.2 0.9 GO:0030118 clathrin coat(GO:0030118)
0.2 3.9 GO:0099634 postsynaptic specialization membrane(GO:0099634)
0.2 3.2 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.2 1.8 GO:0070652 HAUS complex(GO:0070652)
0.2 11.0 GO:0005876 spindle microtubule(GO:0005876)
0.2 9.1 GO:0015030 Cajal body(GO:0015030)
0.2 12.2 GO:0005905 clathrin-coated pit(GO:0005905)
0.2 9.0 GO:0030131 clathrin adaptor complex(GO:0030131)
0.2 1.4 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.2 9.5 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.2 2.4 GO:0031528 microvillus membrane(GO:0031528)
0.2 0.8 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.2 1.0 GO:0099524 region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524)
0.2 2.0 GO:0034709 methylosome(GO:0034709)
0.2 0.8 GO:0036019 endolysosome(GO:0036019)
0.2 9.7 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.2 0.9 GO:0061689 tricellular tight junction(GO:0061689)
0.2 1.4 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.2 6.3 GO:0098636 protein complex involved in cell adhesion(GO:0098636)
0.2 1.3 GO:0016342 catenin complex(GO:0016342)
0.2 2.4 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.2 0.8 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.2 0.6 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.2 6.1 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 14.5 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1 4.4 GO:0005865 striated muscle thin filament(GO:0005865)
0.1 0.9 GO:0044327 dendritic spine head(GO:0044327)
0.1 1.3 GO:0000813 ESCRT I complex(GO:0000813)
0.1 0.3 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306)
0.1 0.8 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 3.2 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 1.5 GO:0045180 basal cortex(GO:0045180)
0.1 1.5 GO:0000812 Swr1 complex(GO:0000812)
0.1 3.2 GO:0097440 apical dendrite(GO:0097440)
0.1 0.4 GO:0035061 interchromatin granule(GO:0035061)
0.1 0.9 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 2.2 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 2.5 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.1 0.9 GO:0005719 nuclear euchromatin(GO:0005719)
0.1 6.4 GO:0016235 aggresome(GO:0016235)
0.1 1.7 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 0.7 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 13.1 GO:0032993 protein-DNA complex(GO:0032993)
0.1 1.3 GO:0010369 chromocenter(GO:0010369)
0.1 1.3 GO:0005883 neurofilament(GO:0005883)
0.1 0.5 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 16.0 GO:0031674 I band(GO:0031674)
0.1 3.9 GO:0030686 90S preribosome(GO:0030686)
0.1 0.9 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.5 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 3.1 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.1 3.8 GO:0097539 ciliary transition fiber(GO:0097539)
0.1 0.3 GO:0071203 WASH complex(GO:0071203)
0.1 0.5 GO:0042575 DNA polymerase complex(GO:0042575)
0.1 13.2 GO:0000775 chromosome, centromeric region(GO:0000775)
0.1 0.5 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.1 1.8 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 14.3 GO:0001726 ruffle(GO:0001726)
0.1 2.7 GO:0031526 brush border membrane(GO:0031526)
0.1 1.5 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 8.2 GO:0030496 midbody(GO:0030496)
0.1 0.3 GO:0032280 symmetric synapse(GO:0032280)
0.1 0.4 GO:0016589 NURF complex(GO:0016589)
0.1 0.3 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.1 5.6 GO:0016363 nuclear matrix(GO:0016363)
0.1 3.3 GO:0045171 intercellular bridge(GO:0045171)
0.1 0.2 GO:0044393 microspike(GO:0044393)
0.1 2.9 GO:0016592 mediator complex(GO:0016592) core mediator complex(GO:0070847)
0.1 0.8 GO:0060170 ciliary membrane(GO:0060170)
0.1 2.0 GO:0035097 histone methyltransferase complex(GO:0035097)
0.1 2.4 GO:0060077 inhibitory synapse(GO:0060077)
0.1 0.6 GO:0000801 central element(GO:0000801)
0.1 0.8 GO:0000346 transcription export complex(GO:0000346)
0.1 3.7 GO:0042629 mast cell granule(GO:0042629)
0.1 0.7 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 0.7 GO:0044292 dendrite terminus(GO:0044292)
0.1 0.3 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.1 0.5 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 0.6 GO:1990909 Wnt signalosome(GO:1990909)
0.1 2.5 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 3.1 GO:0000922 spindle pole(GO:0000922)
0.1 0.1 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.1 1.6 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 3.4 GO:0016605 PML body(GO:0016605)
0.1 1.9 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 2.4 GO:0035869 ciliary transition zone(GO:0035869)
0.1 2.8 GO:0016459 myosin complex(GO:0016459)
0.1 10.5 GO:0031965 nuclear membrane(GO:0031965)
0.1 1.1 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 6.0 GO:0043204 perikaryon(GO:0043204)
0.0 0.7 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 3.2 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.0 GO:0019034 viral replication complex(GO:0019034)
0.0 0.7 GO:0042734 presynaptic membrane(GO:0042734)
0.0 1.3 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 0.4 GO:0001739 sex chromatin(GO:0001739)
0.0 1.0 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.7 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.0 3.8 GO:0000793 condensed chromosome(GO:0000793)
0.0 0.2 GO:0140007 KICSTOR complex(GO:0140007)
0.0 1.3 GO:0001533 cornified envelope(GO:0001533)
0.0 2.1 GO:0005819 spindle(GO:0005819)
0.0 0.3 GO:0031415 NatA complex(GO:0031415)
0.0 1.9 GO:0000792 heterochromatin(GO:0000792)
0.0 1.2 GO:0001772 immunological synapse(GO:0001772)
0.0 0.3 GO:0044754 secondary lysosome(GO:0005767) autolysosome(GO:0044754)
0.0 3.3 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.2 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 1.5 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.6 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.4 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 1.7 GO:0005811 lipid droplet(GO:0005811)
0.0 2.2 GO:0030286 dynein complex(GO:0030286)
0.0 0.3 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.1 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 0.1 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.2 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.6 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.1 GO:0001520 outer dense fiber(GO:0001520)
0.0 1.7 GO:0031225 anchored component of membrane(GO:0031225)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
6.1 24.2 GO:0031721 hemoglobin alpha binding(GO:0031721)
4.3 12.8 GO:0030116 glial cell-derived neurotrophic factor receptor binding(GO:0030116)
3.5 10.6 GO:0046592 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
3.1 24.5 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
3.0 11.9 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
2.7 13.3 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
2.6 15.6 GO:0005344 oxygen transporter activity(GO:0005344)
2.5 9.9 GO:0004477 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
2.5 4.9 GO:0048030 disaccharide binding(GO:0048030)
2.4 9.6 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
2.4 7.2 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
2.2 6.7 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
2.0 10.2 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
2.0 8.0 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
2.0 8.0 GO:0004974 leukotriene receptor activity(GO:0004974)
1.9 9.5 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
1.8 5.5 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
1.7 17.1 GO:0019855 calcium channel inhibitor activity(GO:0019855)
1.7 13.6 GO:0002951 leukotriene-C(4) hydrolase(GO:0002951)
1.6 16.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
1.6 17.7 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
1.6 9.3 GO:0031493 nucleosomal histone binding(GO:0031493)
1.6 10.9 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
1.5 4.5 GO:0052658 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485) inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
1.5 4.4 GO:0052593 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
1.5 14.7 GO:0031014 troponin T binding(GO:0031014)
1.4 7.0 GO:0015254 glycerol channel activity(GO:0015254)
1.3 6.7 GO:0030171 voltage-gated proton channel activity(GO:0030171)
1.3 6.5 GO:0035594 ganglioside binding(GO:0035594)
1.3 3.9 GO:0031896 alpha-1A adrenergic receptor binding(GO:0031691) alpha-1B adrenergic receptor binding(GO:0031692) follicle-stimulating hormone receptor binding(GO:0031762) V2 vasopressin receptor binding(GO:0031896)
1.3 2.5 GO:0004859 phospholipase inhibitor activity(GO:0004859)
1.3 5.0 GO:0003883 CTP synthase activity(GO:0003883)
1.2 18.6 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
1.2 4.8 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
1.2 7.0 GO:0010997 anaphase-promoting complex binding(GO:0010997)
1.1 5.7 GO:0016019 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745) peptidoglycan receptor activity(GO:0016019)
1.1 4.6 GO:0008859 exoribonuclease II activity(GO:0008859)
1.1 12.5 GO:0050693 LBD domain binding(GO:0050693)
1.1 3.4 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
1.1 3.3 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
1.1 10.9 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
1.1 2.1 GO:0031751 D4 dopamine receptor binding(GO:0031751)
1.0 3.1 GO:0010465 nerve growth factor receptor activity(GO:0010465)
1.0 5.2 GO:0000405 bubble DNA binding(GO:0000405)
1.0 9.1 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
1.0 3.9 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
1.0 9.8 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
1.0 2.9 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
1.0 15.4 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.9 2.8 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.9 10.3 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.9 4.6 GO:0031705 bombesin receptor binding(GO:0031705)
0.9 2.8 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.9 11.9 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.9 2.8 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.9 4.6 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.9 3.6 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.9 5.3 GO:0004126 cytidine deaminase activity(GO:0004126)
0.9 2.7 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.9 2.6 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.9 6.1 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.9 6.1 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.9 8.7 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.9 7.0 GO:0070644 vitamin D response element binding(GO:0070644)
0.9 8.7 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.9 2.6 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.8 2.5 GO:0009378 four-way junction helicase activity(GO:0009378)
0.8 4.1 GO:0042895 antibiotic transporter activity(GO:0042895)
0.8 9.9 GO:0004716 signal transducer, downstream of receptor, with protein tyrosine kinase activity(GO:0004716)
0.8 12.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.8 2.4 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.8 2.4 GO:0004461 lactose synthase activity(GO:0004461)
0.8 4.0 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.8 8.4 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.7 3.0 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.7 2.2 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.7 11.2 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol trisphosphate phosphatase activity(GO:0046030)
0.7 4.4 GO:0061649 ubiquitin modification-dependent histone binding(GO:0061649)
0.7 32.5 GO:0003785 actin monomer binding(GO:0003785)
0.7 3.6 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.7 2.2 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.7 10.0 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.7 4.3 GO:0004111 creatine kinase activity(GO:0004111)
0.7 2.8 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.7 2.1 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.7 14.6 GO:0042608 T cell receptor binding(GO:0042608)
0.7 6.2 GO:0070061 fructose binding(GO:0070061)
0.7 2.1 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.7 6.1 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.7 0.7 GO:0030348 syntaxin-3 binding(GO:0030348)
0.7 2.0 GO:0030519 snoRNP binding(GO:0030519)
0.7 11.3 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.7 2.6 GO:0031849 olfactory receptor binding(GO:0031849)
0.6 2.6 GO:0004104 cholinesterase activity(GO:0004104)
0.6 21.3 GO:0008187 poly-pyrimidine tract binding(GO:0008187)
0.6 1.9 GO:0030629 U6 snRNA 3'-end binding(GO:0030629)
0.6 14.1 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.6 4.5 GO:0004498 calcidiol 1-monooxygenase activity(GO:0004498)
0.6 1.9 GO:0038181 bile acid receptor activity(GO:0038181)
0.6 2.5 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.6 8.8 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.6 19.3 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.6 4.3 GO:0000150 recombinase activity(GO:0000150)
0.6 2.4 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.6 1.8 GO:0030226 aminophospholipid transporter activity(GO:0015247) apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.6 4.8 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.6 2.9 GO:0070051 fibrinogen binding(GO:0070051)
0.6 2.9 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.6 2.3 GO:0042731 PH domain binding(GO:0042731)
0.6 2.3 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.6 4.7 GO:0050786 RAGE receptor binding(GO:0050786)
0.6 3.4 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.6 7.8 GO:0005523 tropomyosin binding(GO:0005523)
0.6 4.5 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.6 3.9 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.5 11.5 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.5 1.6 GO:0016748 succinyltransferase activity(GO:0016748)
0.5 14.9 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.5 1.6 GO:0023030 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.5 2.6 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.5 3.1 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.5 30.8 GO:0030507 spectrin binding(GO:0030507)
0.5 5.7 GO:0030274 LIM domain binding(GO:0030274)
0.5 2.9 GO:1990932 5.8S rRNA binding(GO:1990932)
0.5 1.4 GO:0070615 nucleosome-dependent ATPase activity(GO:0070615)
0.5 1.4 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.4 1.3 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.4 1.8 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.4 6.4 GO:0031432 titin binding(GO:0031432)
0.4 6.7 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.4 0.8 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.4 9.1 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.4 8.2 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.4 2.8 GO:0001851 complement component C3b binding(GO:0001851)
0.4 2.8 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.4 2.4 GO:0031779 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.4 2.7 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.4 0.8 GO:0035184 histone threonine kinase activity(GO:0035184)
0.4 12.2 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.4 1.9 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.4 6.4 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.4 3.7 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.4 1.1 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.4 1.5 GO:0004074 biliverdin reductase activity(GO:0004074)
0.4 20.1 GO:0070888 E-box binding(GO:0070888)
0.4 2.6 GO:0043559 insulin binding(GO:0043559)
0.4 2.5 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.4 2.8 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.3 1.7 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.3 1.4 GO:0086077 gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
0.3 2.4 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.3 4.5 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.3 2.1 GO:0035827 rubidium ion transmembrane transporter activity(GO:0035827)
0.3 1.7 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.3 6.7 GO:0017049 GTP-Rho binding(GO:0017049)
0.3 2.0 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.3 2.3 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
0.3 3.0 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.3 3.0 GO:0120013 intermembrane lipid transfer activity(GO:0120013)
0.3 1.6 GO:0032027 myosin light chain binding(GO:0032027)
0.3 2.3 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.3 1.0 GO:0045340 mercury ion binding(GO:0045340)
0.3 1.0 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.3 6.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.3 1.3 GO:0004092 carnitine O-acetyltransferase activity(GO:0004092)
0.3 9.6 GO:0019956 chemokine binding(GO:0019956)
0.3 13.7 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.3 4.4 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.3 1.6 GO:0038100 nodal binding(GO:0038100)
0.3 1.6 GO:0097108 hedgehog family protein binding(GO:0097108)
0.3 5.0 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.3 7.8 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.3 2.8 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.3 7.0 GO:0005540 hyaluronic acid binding(GO:0005540)
0.3 0.9 GO:0019002 GMP binding(GO:0019002)
0.3 7.5 GO:0000146 microfilament motor activity(GO:0000146)
0.3 1.5 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.3 3.3 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.3 3.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.3 1.7 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.3 0.9 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.3 3.1 GO:0031005 filamin binding(GO:0031005)
0.3 3.7 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.3 2.3 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.3 0.8 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.3 2.5 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.3 4.8 GO:0030215 semaphorin receptor binding(GO:0030215)
0.3 2.5 GO:0034711 inhibin binding(GO:0034711)
0.3 1.4 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.3 2.2 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.3 1.1 GO:0070976 calcium-independent protein kinase C activity(GO:0004699) TIR domain binding(GO:0070976)
0.3 1.9 GO:0048495 Roundabout binding(GO:0048495)
0.3 3.4 GO:0005522 profilin binding(GO:0005522)
0.3 51.2 GO:0051015 actin filament binding(GO:0051015)
0.3 8.2 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.3 1.5 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.3 0.8 GO:0008176 tRNA (guanine-N7-)-methyltransferase activity(GO:0008176)
0.2 5.3 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.2 4.5 GO:0035613 RNA stem-loop binding(GO:0035613)
0.2 1.9 GO:0003688 DNA replication origin binding(GO:0003688)
0.2 1.6 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.2 4.0 GO:0050811 GABA receptor binding(GO:0050811)
0.2 2.2 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.2 0.7 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.2 1.3 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.2 0.4 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.2 1.3 GO:0008518 reduced folate carrier activity(GO:0008518)
0.2 1.5 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.2 0.6 GO:0042007 interleukin-18 binding(GO:0042007)
0.2 7.2 GO:0017147 Wnt-protein binding(GO:0017147)
0.2 1.9 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.2 1.5 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.2 6.4 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.2 0.2 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.2 5.5 GO:0050321 tau-protein kinase activity(GO:0050321)
0.2 0.6 GO:0034594 phosphatidylinositol trisphosphate phosphatase activity(GO:0034594)
0.2 2.9 GO:1990226 histone methyltransferase binding(GO:1990226)
0.2 1.0 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.2 9.9 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.2 3.8 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.2 1.8 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.2 1.0 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.2 1.8 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.2 2.6 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.2 1.2 GO:0005042 netrin receptor activity(GO:0005042)
0.2 0.8 GO:0050347 trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347)
0.2 1.2 GO:0008131 primary amine oxidase activity(GO:0008131)
0.2 0.8 GO:1990460 leptin receptor binding(GO:1990460)
0.2 1.3 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.2 1.1 GO:0005499 vitamin D binding(GO:0005499)
0.2 1.3 GO:0051434 BH3 domain binding(GO:0051434)
0.2 1.1 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.2 1.4 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.2 0.5 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.2 0.5 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.2 0.5 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.2 2.8 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.2 5.9 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.2 6.9 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.2 0.7 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.2 1.7 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.2 17.6 GO:0051087 chaperone binding(GO:0051087)
0.2 1.0 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.2 1.2 GO:1990188 euchromatin binding(GO:1990188)
0.2 2.5 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.2 0.8 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.2 1.0 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.2 0.8 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.2 1.1 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.2 2.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.2 0.6 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.2 0.9 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.2 1.3 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.2 1.1 GO:0031702 angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
0.2 0.8 GO:0034056 estrogen response element binding(GO:0034056)
0.2 1.1 GO:0043208 glycosphingolipid binding(GO:0043208)
0.2 0.9 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.2 1.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.2 0.6 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.2 1.2 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.1 0.4 GO:0019238 cyclohydrolase activity(GO:0019238)
0.1 5.2 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 1.6 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 2.9 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 0.7 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 1.8 GO:0003680 AT DNA binding(GO:0003680)
0.1 0.8 GO:0042805 actinin binding(GO:0042805)
0.1 1.8 GO:0070300 phosphatidic acid binding(GO:0070300)
0.1 3.3 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 4.7 GO:0005112 Notch binding(GO:0005112)
0.1 1.5 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.1 7.6 GO:0047485 protein N-terminus binding(GO:0047485)
0.1 0.7 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.1 1.4 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.8 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.1 2.8 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 0.7 GO:0033188 ceramide phosphoethanolamine synthase activity(GO:0002950) sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 6.6 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 7.2 GO:0004601 peroxidase activity(GO:0004601)
0.1 1.9 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.1 2.8 GO:0097110 scaffold protein binding(GO:0097110)
0.1 2.5 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 0.2 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 0.7 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.1 0.9 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.1 1.2 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.1 2.9 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 3.4 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) tumor necrosis factor binding(GO:0043120)
0.1 0.3 GO:0030943 mitochondrion targeting sequence binding(GO:0030943)
0.1 2.7 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 0.3 GO:0001962 alpha-1,3-galactosyltransferase activity(GO:0001962)
0.1 1.1 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 0.6 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 2.4 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.1 1.0 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.1 0.8 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.1 0.8 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.1 0.9 GO:0051393 alpha-actinin binding(GO:0051393)
0.1 2.0 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 0.4 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 1.2 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 0.4 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.1 1.7 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 2.0 GO:0004697 protein kinase C activity(GO:0004697)
0.1 17.6 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 1.6 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 0.7 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 3.9 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 0.3 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 0.7 GO:0035497 cAMP response element binding(GO:0035497)
0.1 1.8 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 0.8 GO:0071837 HMG box domain binding(GO:0071837)
0.1 0.3 GO:0099103 channel activator activity(GO:0099103) potassium channel activator activity(GO:0099104)
0.1 1.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.8 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 0.7 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 2.8 GO:0008536 Ran GTPase binding(GO:0008536)
0.1 0.8 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 0.3 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.1 0.2 GO:0035240 dopamine neurotransmitter receptor activity(GO:0004952) dopamine binding(GO:0035240)
0.1 0.3 GO:0036310 annealing helicase activity(GO:0036310)
0.1 1.5 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 2.5 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 3.1 GO:0005109 frizzled binding(GO:0005109)
0.1 0.7 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.1 2.1 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 0.8 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.1 0.2 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.1 2.4 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.1 0.6 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.1 0.5 GO:0004954 prostanoid receptor activity(GO:0004954)
0.1 0.3 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 0.4 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.3 GO:0002135 CTP binding(GO:0002135)
0.1 0.6 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.1 1.4 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 0.3 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.1 0.6 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 3.4 GO:0019843 rRNA binding(GO:0019843)
0.1 5.6 GO:0097472 cyclin-dependent protein kinase activity(GO:0097472)
0.1 0.6 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.1 3.5 GO:0044325 ion channel binding(GO:0044325)
0.1 1.4 GO:0031489 myosin V binding(GO:0031489)
0.1 0.2 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 1.7 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.1 10.9 GO:0008301 DNA binding, bending(GO:0008301)
0.1 2.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 1.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.8 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.1 4.2 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.1 3.8 GO:0051082 unfolded protein binding(GO:0051082)
0.1 0.7 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.1 0.6 GO:0016505 peptidase activator activity involved in apoptotic process(GO:0016505)
0.1 1.5 GO:0019894 kinesin binding(GO:0019894)
0.1 1.2 GO:0008252 nucleotidase activity(GO:0008252)
0.1 1.0 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 0.5 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.1 0.5 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 1.6 GO:0042162 telomeric DNA binding(GO:0042162)
0.1 0.9 GO:0005521 lamin binding(GO:0005521)
0.1 0.8 GO:0017160 Ral GTPase binding(GO:0017160)
0.1 0.3 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 0.3 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.1 0.7 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.7 GO:0001221 transcription cofactor binding(GO:0001221)
0.0 0.1 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.2 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 1.4 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.9 GO:0016805 dipeptidase activity(GO:0016805)
0.0 1.4 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 0.3 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.9 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.6 GO:0070840 dynein complex binding(GO:0070840)
0.0 1.2 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.2 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750) lipoprotein particle receptor binding(GO:0070325)
0.0 0.4 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.2 GO:0005497 androgen binding(GO:0005497)
0.0 0.1 GO:0034617 tetrahydrobiopterin binding(GO:0034617)
0.0 0.3 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
0.0 0.6 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.4 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.3 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.1 GO:0034211 GTP-dependent protein kinase activity(GO:0034211)
0.0 0.2 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.6 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 1.5 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.7 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 4.5 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 1.1 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.1 GO:0050694 galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.1 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.2 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.2 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 1.0 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.8 GO:0016209 antioxidant activity(GO:0016209)
0.0 0.1 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.4 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.1 GO:0070739 protein-glutamic acid ligase activity(GO:0070739)
0.0 0.4 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.5 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.3 GO:0061783 peptidoglycan muralytic activity(GO:0061783)
0.0 0.1 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
0.0 0.2 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.1 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.0 0.1 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.1 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.1 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.0 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.0 0.4 GO:0000049 tRNA binding(GO:0000049)
0.0 0.1 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 1.6 GO:0004984 olfactory receptor activity(GO:0004984)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 20.6 ST_PAC1_RECEPTOR_PATHWAY PAC1 Receptor Pathway
1.0 18.1 PID_S1P_S1P4_PATHWAY S1P4 pathway
1.0 1.0 ST_GA13_PATHWAY G alpha 13 Pathway
0.9 1.8 PID_IGF1_PATHWAY IGF1 pathway
0.9 7.7 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.7 11.2 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events
0.6 1.9 PID_GMCSF_PATHWAY GMCSF-mediated signaling events
0.6 9.3 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.5 6.9 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.5 15.0 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.4 24.1 SIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.4 7.3 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.4 18.2 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.4 14.7 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.4 18.0 PID_RAS_PATHWAY Regulation of Ras family activation
0.3 7.0 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.3 7.6 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.3 17.4 PID_PLK1_PATHWAY PLK1 signaling events
0.3 23.9 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.3 4.2 PID_THROMBIN_PAR1_PATHWAY PAR1-mediated thrombin signaling events
0.3 4.1 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.3 15.9 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.3 28.7 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.3 15.5 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.2 2.7 ST_INTERLEUKIN_4_PATHWAY Interleukin 4 (IL-4) Pathway
0.2 3.5 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.2 3.9 PID_IL5_PATHWAY IL5-mediated signaling events
0.2 5.3 PID_SYNDECAN_2_PATHWAY Syndecan-2-mediated signaling events
0.2 15.1 PID_P53_REGULATION_PATHWAY p53 pathway
0.2 8.1 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.2 1.6 PID_LYMPH_ANGIOGENESIS_PATHWAY VEGFR3 signaling in lymphatic endothelium
0.2 12.4 PID_ATF2_PATHWAY ATF-2 transcription factor network
0.2 2.2 PID_IL8_CXCR2_PATHWAY IL8- and CXCR2-mediated signaling events
0.2 3.4 ST_GA12_PATHWAY G alpha 12 Pathway
0.2 2.9 PID_ER_NONGENOMIC_PATHWAY Plasma membrane estrogen receptor signaling
0.2 3.7 PID_EPHB_FWD_PATHWAY EPHB forward signaling
0.2 7.5 PID_AMB2_NEUTROPHILS_PATHWAY amb2 Integrin signaling
0.2 5.9 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.2 10.1 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.2 4.9 PID_FAK_PATHWAY Signaling events mediated by focal adhesion kinase
0.2 3.8 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.1 1.8 ST_GAQ_PATHWAY G alpha q Pathway
0.1 4.6 PID_IL4_2PATHWAY IL4-mediated signaling events
0.1 5.2 PID_PI3KCI_PATHWAY Class I PI3K signaling events
0.1 2.6 PID_ENDOTHELIN_PATHWAY Endothelins
0.1 2.7 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.1 3.8 PID_ATM_PATHWAY ATM pathway
0.1 2.6 PID_PTP1B_PATHWAY Signaling events mediated by PTP1B
0.1 1.4 PID_INTEGRIN_CS_PATHWAY Integrin family cell surface interactions
0.1 0.2 PID_NFKAPPAB_CANONICAL_PATHWAY Canonical NF-kappaB pathway
0.1 1.1 SIG_BCR_SIGNALING_PATHWAY Members of the BCR signaling pathway
0.1 35.9 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.1 1.1 PID_INTEGRIN_A4B1_PATHWAY Alpha4 beta1 integrin signaling events
0.1 6.1 PID_NOTCH_PATHWAY Notch signaling pathway
0.1 1.0 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.1 0.9 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 0.8 PID_IL3_PATHWAY IL3-mediated signaling events
0.1 4.0 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.1 0.7 PID_IL2_PI3K_PATHWAY IL2 signaling events mediated by PI3K
0.1 2.5 PID_RAC1_PATHWAY RAC1 signaling pathway
0.1 2.1 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.1 1.5 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.1 0.7 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 1.9 PID_BARD1_PATHWAY BARD1 signaling events
0.1 1.9 PID_FCER1_PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 2.5 PID_INTEGRIN1_PATHWAY Beta1 integrin cell surface interactions
0.1 1.7 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 1.5 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.1 0.8 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.1 0.7 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 3.2 PID_P75_NTR_PATHWAY p75(NTR)-mediated signaling
0.1 2.1 PID_AURORA_B_PATHWAY Aurora B signaling
0.1 0.6 PID_IL23_PATHWAY IL23-mediated signaling events
0.1 2.7 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.1 0.8 PID_MYC_PATHWAY C-MYC pathway
0.0 3.8 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.8 PID_P38_ALPHA_BETA_PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.3 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.0 0.2 ST_G_ALPHA_I_PATHWAY G alpha i Pathway
0.0 0.6 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 0.2 PID_VEGFR1_PATHWAY VEGFR1 specific signals
0.0 0.2 PID_TCPTP_PATHWAY Signaling events mediated by TCPTP
0.0 0.4 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.3 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.0 1.4 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.0 0.2 ST_TUMOR_NECROSIS_FACTOR_PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.3 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 0.2 PID_ERBB2_ERBB3_PATHWAY ErbB2/ErbB3 signaling events
0.0 0.3 PID_ATR_PATHWAY ATR signaling pathway
0.0 1.1 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.2 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.0 0.5 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.0 0.3 PID_CXCR4_PATHWAY CXCR4-mediated signaling events
0.0 0.3 PID_ERBB1_DOWNSTREAM_PATHWAY ErbB1 downstream signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 6.1 REACTOME_TRANSFERRIN_ENDOCYTOSIS_AND_RECYCLING Genes involved in Transferrin endocytosis and recycling
1.0 37.2 REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.9 7.0 REACTOME_E2F_ENABLED_INHIBITION_OF_PRE_REPLICATION_COMPLEX_FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.8 11.4 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.8 20.9 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
0.7 10.9 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.6 12.8 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.6 7.2 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.6 9.3 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.6 12.0 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.6 6.9 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.6 3.4 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.6 25.3 REACTOME_G_PROTEIN_ACTIVATION Genes involved in G-protein activation
0.5 13.4 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.5 6.7 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.5 12.7 REACTOME_ACTIVATION_OF_GENES_BY_ATF4 Genes involved in Activation of Genes by ATF4
0.5 12.8 REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB Genes involved in PKA-mediated phosphorylation of CREB
0.5 25.3 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.5 13.2 REACTOME_ACYL_CHAIN_REMODELLING_OF_PC Genes involved in Acyl chain remodelling of PC
0.5 9.8 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.5 7.7 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.4 4.0 REACTOME_INHIBITION_OF_REPLICATION_INITIATION_OF_DAMAGED_DNA_BY_RB1_E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.4 18.0 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.4 21.6 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.4 18.9 REACTOME_RECYCLING_PATHWAY_OF_L1 Genes involved in Recycling pathway of L1
0.4 6.1 REACTOME_GRB2_SOS_PROVIDES_LINKAGE_TO_MAPK_SIGNALING_FOR_INTERGRINS_ Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.4 5.3 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.4 10.0 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.4 7.7 REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.4 7.3 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.4 9.3 REACTOME_REGULATION_OF_SIGNALING_BY_CBL Genes involved in Regulation of signaling by CBL
0.4 2.1 REACTOME_THROMBOXANE_SIGNALLING_THROUGH_TP_RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.4 8.8 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.3 2.4 REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.3 9.2 REACTOME_BASIGIN_INTERACTIONS Genes involved in Basigin interactions
0.3 7.2 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.3 1.3 REACTOME_CD28_DEPENDENT_VAV1_PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.3 0.6 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.3 6.1 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.3 10.8 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.3 1.7 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
0.3 2.6 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.3 6.5 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.3 0.8 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.3 2.9 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.3 8.1 REACTOME_NEP_NS2_INTERACTS_WITH_THE_CELLULAR_EXPORT_MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.2 4.3 REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.2 12.9 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.2 3.8 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.2 2.1 REACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.2 2.6 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.2 21.1 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.2 3.9 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.2 3.0 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.2 2.3 REACTOME_PROSTANOID_LIGAND_RECEPTORS Genes involved in Prostanoid ligand receptors
0.2 6.9 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.2 5.3 REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS Genes involved in G alpha (z) signalling events
0.2 2.0 REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.2 5.7 REACTOME_AMYLOIDS Genes involved in Amyloids
0.2 0.8 REACTOME_INHIBITION_OF_INSULIN_SECRETION_BY_ADRENALINE_NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.2 4.8 REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE Genes involved in GPVI-mediated activation cascade
0.2 10.1 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.2 0.8 REACTOME_REGULATION_OF_KIT_SIGNALING Genes involved in Regulation of KIT signaling
0.2 9.8 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.2 1.3 REACTOME_INFLAMMASOMES Genes involved in Inflammasomes
0.2 1.7 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.2 1.5 REACTOME_OPSINS Genes involved in Opsins
0.2 4.8 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.2 9.5 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.2 13.8 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.2 12.3 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.2 0.5 REACTOME_ASSOCIATION_OF_LICENSING_FACTORS_WITH_THE_PRE_REPLICATIVE_COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.2 1.3 REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.2 4.5 REACTOME_G1_PHASE Genes involved in G1 Phase
0.2 2.0 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 7.8 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 0.1 REACTOME_NEF_MEDIATES_DOWN_MODULATION_OF_CELL_SURFACE_RECEPTORS_BY_RECRUITING_THEM_TO_CLATHRIN_ADAPTERS Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
0.1 2.3 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 5.8 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.1 2.6 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.1 2.1 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.1 2.4 REACTOME_MEIOSIS Genes involved in Meiosis
0.1 1.4 REACTOME_TRAF6_MEDIATED_INDUCTION_OF_TAK1_COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.1 1.3 REACTOME_POST_NMDA_RECEPTOR_ACTIVATION_EVENTS Genes involved in Post NMDA receptor activation events
0.1 6.3 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 2.8 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 1.3 REACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.1 1.9 REACTOME_PHOSPHORYLATION_OF_THE_APC_C Genes involved in Phosphorylation of the APC/C
0.1 1.3 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 5.4 REACTOME_MRNA_3_END_PROCESSING Genes involved in mRNA 3'-end processing
0.1 1.8 REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.1 3.4 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 22.4 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.1 0.8 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 1.1 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM Genes involved in Abacavir transport and metabolism
0.1 1.2 REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1 1.8 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 6.2 REACTOME_POTASSIUM_CHANNELS Genes involved in Potassium Channels
0.1 2.1 REACTOME_KINESINS Genes involved in Kinesins
0.1 3.3 REACTOME_PEROXISOMAL_LIPID_METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 3.1 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 1.8 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 1.1 REACTOME_IL_RECEPTOR_SHC_SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 1.2 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 5.0 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 2.0 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.1 0.8 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 3.7 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 4.0 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.1 0.8 REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 0.7 REACTOME_POST_TRANSLATIONAL_MODIFICATION_SYNTHESIS_OF_GPI_ANCHORED_PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.1 0.8 REACTOME_PLC_BETA_MEDIATED_EVENTS Genes involved in PLC beta mediated events
0.1 0.7 REACTOME_DEFENSINS Genes involved in Defensins
0.1 1.1 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism
0.1 1.5 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.1 4.8 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 1.7 REACTOME_GAB1_SIGNALOSOME Genes involved in GAB1 signalosome
0.1 1.0 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
0.1 1.9 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 3.4 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.0 1.1 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 6.6 REACTOME_G_ALPHA_I_SIGNALLING_EVENTS Genes involved in G alpha (i) signalling events
0.0 1.0 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.6 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.4 REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 0.5 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.0 0.6 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.3 REACTOME_NOD1_2_SIGNALING_PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.7 REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS Genes involved in Activation of ATR in response to replication stress
0.0 0.5 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.0 0.7 REACTOME_ELONGATION_ARREST_AND_RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.4 REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.8 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.0 1.4 REACTOME_RNA_POL_I_RNA_POL_III_AND_MITOCHONDRIAL_TRANSCRIPTION Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
0.0 0.4 REACTOME_DOWNSTREAM_TCR_SIGNALING Genes involved in Downstream TCR signaling
0.0 0.4 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.3 REACTOME_CHROMOSOME_MAINTENANCE Genes involved in Chromosome Maintenance
0.0 0.1 REACTOME_ENOS_ACTIVATION_AND_REGULATION Genes involved in eNOS activation and regulation
0.0 0.5 REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.9 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.1 REACTOME_HIGHLY_CALCIUM_PERMEABLE_POSTSYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors