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GSE58827: Dynamics of the Mouse Liver

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Results for Mafa

Z-value: 0.74

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Transcription factors associated with Mafa

Gene Symbol Gene ID Gene Info
Mafa
ENSMUSG00000047591.4 v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Mafamm10_v2_chr15_-_75747922_757479220.173.3e-01Click!

Activity profile of Mafa motif

Sorted Z-values of Mafa motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_142679533 10.14 ENSMUST00000162317.1
ENSMUST00000125933.1
ENSMUST00000105931.1
ENSMUST00000105930.1
ENSMUST00000105933.1
ENSMUST00000105932.1
ENSMUST00000000220.2
Ins2
insulin II
chr19_+_52264323 8.85 ENSMUST00000039652.4
Ins1
insulin I
chr1_-_121327672 2.80 ENSMUST00000159085.1
ENSMUST00000159125.1
ENSMUST00000161818.1
Insig2
insulin induced gene 2
chr1_-_121328024 2.78 ENSMUST00000003818.7
Insig2
insulin induced gene 2
chr1_-_121327734 2.69 ENSMUST00000160968.1
ENSMUST00000162582.1
Insig2
insulin induced gene 2
chr1_-_169747634 2.57 ENSMUST00000027991.5
ENSMUST00000111357.1
Rgs4
regulator of G-protein signaling 4
chr1_-_121327776 2.45 ENSMUST00000160688.1
Insig2
insulin induced gene 2
chr1_+_171214013 2.34 ENSMUST00000111328.1
Nr1i3
nuclear receptor subfamily 1, group I, member 3
chr10_+_87859593 2.19 ENSMUST00000126490.1
Igf1
insulin-like growth factor 1
chr9_-_107679592 2.15 ENSMUST00000010205.7
Gnat1
guanine nucleotide binding protein, alpha transducing 1
chr16_+_91269759 2.14 ENSMUST00000056882.5
Olig1
oligodendrocyte transcription factor 1
chrX_-_139782353 1.92 ENSMUST00000101217.3
Ripply1
ripply1 homolog (zebrafish)
chr1_+_171213969 1.79 ENSMUST00000005820.4
ENSMUST00000075469.5
ENSMUST00000155126.1
Nr1i3
nuclear receptor subfamily 1, group I, member 3
chr1_-_135167606 1.77 ENSMUST00000027682.8
Gpr37l1
G protein-coupled receptor 37-like 1
chr4_+_102254993 1.67 ENSMUST00000106908.2
Pde4b
phosphodiesterase 4B, cAMP specific
chr2_-_166155272 1.56 ENSMUST00000088086.3
Sulf2
sulfatase 2
chr13_+_24943144 1.55 ENSMUST00000021773.5
Gpld1
glycosylphosphatidylinositol specific phospholipase D1
chr9_-_48835932 1.46 ENSMUST00000093852.3
Zbtb16
zinc finger and BTB domain containing 16
chr6_-_35308110 1.28 ENSMUST00000031868.4
Slc13a4
solute carrier family 13 (sodium/sulfate symporters), member 4
chr4_-_66404512 1.13 ENSMUST00000068214.4
Astn2
astrotactin 2
chr14_-_41185188 1.04 ENSMUST00000077136.3
Sftpd
surfactant associated protein D
chr12_-_86884808 1.02 ENSMUST00000038422.6
Irf2bpl
interferon regulatory factor 2 binding protein-like
chr1_+_106171752 0.99 ENSMUST00000061047.6
Phlpp1
PH domain and leucine rich repeat protein phosphatase 1
chr1_-_105356658 0.92 ENSMUST00000058688.5
ENSMUST00000172299.1
Rnf152
ring finger protein 152
chr17_-_46752170 0.92 ENSMUST00000121671.1
ENSMUST00000059844.6
Cnpy3
canopy 3 homolog (zebrafish)
chr10_-_84440591 0.87 ENSMUST00000020220.8
Nuak1
NUAK family, SNF1-like kinase, 1
chr19_-_36119833 0.83 ENSMUST00000025718.8
Ankrd1
ankyrin repeat domain 1 (cardiac muscle)
chr3_+_108653907 0.76 ENSMUST00000106609.1
Clcc1
chloride channel CLIC-like 1
chr16_+_96467606 0.74 ENSMUST00000061739.8
Pcp4
Purkinje cell protein 4
chr8_+_35375719 0.72 ENSMUST00000070481.6
Ppp1r3b
protein phosphatase 1, regulatory (inhibitor) subunit 3B
chr12_+_105453831 0.71 ENSMUST00000178224.1
D430019H16Rik
RIKEN cDNA D430019H16 gene
chr4_-_141416002 0.68 ENSMUST00000006378.2
ENSMUST00000105788.1
Clcnkb
chloride channel Kb
chr7_-_67759735 0.62 ENSMUST00000074233.4
ENSMUST00000051389.8
Synm
synemin, intermediate filament protein
chr4_+_43406435 0.59 ENSMUST00000098106.2
ENSMUST00000139198.1
Rusc2
RUN and SH3 domain containing 2
chr2_-_125506385 0.53 ENSMUST00000028633.6
Fbn1
fibrillin 1
chr6_+_85187438 0.50 ENSMUST00000045942.8
Emx1
empty spiracles homeobox 1
chr9_-_105131775 0.47 ENSMUST00000035179.6
Nudt16
nudix (nucleoside diphosphate linked moiety X)-type motif 16
chr11_+_98927785 0.47 ENSMUST00000107474.1
Rara
retinoic acid receptor, alpha
chr7_-_101011976 0.46 ENSMUST00000178340.1
ENSMUST00000037540.3
P2ry2
purinergic receptor P2Y, G-protein coupled 2
chr3_-_153944632 0.43 ENSMUST00000072697.6
Acadm
acyl-Coenzyme A dehydrogenase, medium chain
chr16_-_17576631 0.42 ENSMUST00000164545.1
ENSMUST00000164490.1
ENSMUST00000172164.1
Slc7a4
solute carrier family 7 (cationic amino acid transporter, y+ system), member 4
chr4_+_116720920 0.42 ENSMUST00000045542.6
ENSMUST00000106459.1
Tesk2
testis-specific kinase 2
chr9_-_98033181 0.42 ENSMUST00000035027.6
Clstn2
calsyntenin 2
chr13_+_93771656 0.41 ENSMUST00000091403.4
Arsb
arylsulfatase B
chr5_+_124629050 0.41 ENSMUST00000037865.8
Atp6v0a2
ATPase, H+ transporting, lysosomal V0 subunit A2
chr5_-_24423516 0.40 ENSMUST00000030814.6
Cdk5
cyclin-dependent kinase 5
chr17_-_72603709 0.39 ENSMUST00000086639.4
Alk
anaplastic lymphoma kinase
chrX_-_20950597 0.38 ENSMUST00000009550.7
Elk1
ELK1, member of ETS oncogene family
chr17_-_47010513 0.37 ENSMUST00000113337.2
ENSMUST00000113335.2
Ubr2
ubiquitin protein ligase E3 component n-recognin 2
chr5_-_142509653 0.37 ENSMUST00000110784.1
Radil
Ras association and DIL domains
chrX_+_152178945 0.35 ENSMUST00000096275.4
Iqsec2
IQ motif and Sec7 domain 2
chr12_-_87299705 0.35 ENSMUST00000125733.1
Ism2
isthmin 2 homolog (zebrafish)
chr11_-_119228461 0.34 ENSMUST00000036113.3
Tbc1d16
TBC1 domain family, member 16
chr19_+_27217011 0.34 ENSMUST00000164746.1
ENSMUST00000172302.1
Vldlr
very low density lipoprotein receptor
chr4_+_155601854 0.34 ENSMUST00000118607.1
Slc35e2
solute carrier family 35, member E2
chr5_+_111417263 0.33 ENSMUST00000094463.4
Mn1
meningioma 1
chr11_+_87595646 0.33 ENSMUST00000134216.1
Mtmr4
myotubularin related protein 4
chr5_+_24423805 0.33 ENSMUST00000153274.1
Slc4a2
solute carrier family 4 (anion exchanger), member 2
chr2_-_92401237 0.32 ENSMUST00000050312.2
Mapk8ip1
mitogen-activated protein kinase 8 interacting protein 1
chrX_-_97377190 0.32 ENSMUST00000037353.3
Eda2r
ectodysplasin A2 receptor
chr1_+_146495621 0.31 ENSMUST00000074622.4
Brinp3
bone morphogenetic protein/retinoic acid inducible neural specific 3
chr16_+_64851991 0.30 ENSMUST00000067744.7
Cggbp1
CGG triplet repeat binding protein 1
chr19_+_27217357 0.30 ENSMUST00000047645.6
ENSMUST00000167487.1
Vldlr
very low density lipoprotein receptor
chr10_+_58813359 0.30 ENSMUST00000135526.2
ENSMUST00000153031.1
Sh3rf3
SH3 domain containing ring finger 3
chr9_-_44454757 0.29 ENSMUST00000047740.2
Upk2
uroplakin 2
chr4_+_102254739 0.28 ENSMUST00000106907.2
Pde4b
phosphodiesterase 4B, cAMP specific
chr17_-_27513341 0.27 ENSMUST00000118161.1
Grm4
glutamate receptor, metabotropic 4
chr9_+_45906513 0.27 ENSMUST00000039059.6
Pcsk7
proprotein convertase subtilisin/kexin type 7
chr4_+_155601414 0.26 ENSMUST00000105608.2
Slc35e2
solute carrier family 35, member E2
chr1_-_58695944 0.25 ENSMUST00000055313.7
Als2cr12
amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 12 (human)
chrX_+_98149666 0.22 ENSMUST00000052837.7
Ar
androgen receptor
chr4_+_59003121 0.19 ENSMUST00000095070.3
ENSMUST00000174664.1
Dnajc25
Gm20503
DnaJ (Hsp40) homolog, subfamily C, member 25
predicted gene 20503
chr9_-_51077064 0.19 ENSMUST00000098782.3
Layn
layilin
chr11_-_59787636 0.18 ENSMUST00000125307.1
Pld6
phospholipase D family, member 6
chr3_-_108940445 0.18 ENSMUST00000050914.1
Gm9857
predicted gene 9857
chr7_+_18065929 0.16 ENSMUST00000032520.2
ENSMUST00000108487.2
ENSMUST00000108483.1
Ceacam12
carcinoembryonic antigen-related cell adhesion molecule 12
chrX_-_122397351 0.16 ENSMUST00000079490.4
Nap1l3
nucleosome assembly protein 1-like 3
chr11_-_66525795 0.16 ENSMUST00000123454.1
Shisa6
shisa homolog 6 (Xenopus laevis)
chr5_-_124187150 0.14 ENSMUST00000161938.1
Pitpnm2
phosphatidylinositol transfer protein, membrane-associated 2
chr16_+_17331371 0.13 ENSMUST00000023450.6
ENSMUST00000161034.1
Serpind1
serine (or cysteine) peptidase inhibitor, clade D, member 1
chr9_-_109059711 0.12 ENSMUST00000061973.4
Trex1
three prime repair exonuclease 1
chr4_-_58912678 0.12 ENSMUST00000144512.1
ENSMUST00000102889.3
ENSMUST00000055822.8
AI314180
expressed sequence AI314180
chr9_-_98032983 0.11 ENSMUST00000162295.1
Clstn2
calsyntenin 2
chr7_-_12684991 0.11 ENSMUST00000172743.1
ENSMUST00000167771.1
Vmn2r55
vomeronasal 2, receptor 55
chr10_-_75932468 0.10 ENSMUST00000120281.1
ENSMUST00000000924.6
Mmp11
matrix metallopeptidase 11
chr11_-_66525964 0.09 ENSMUST00000066679.6
Shisa6
shisa homolog 6 (Xenopus laevis)
chrX_+_104482774 0.09 ENSMUST00000087867.5
Uprt
uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae)
chr1_-_38836090 0.08 ENSMUST00000147695.1
Lonrf2
LON peptidase N-terminal domain and ring finger 2
chr9_-_109059216 0.08 ENSMUST00000112053.1
Trex1
three prime repair exonuclease 1
chr8_+_105373265 0.08 ENSMUST00000160650.1
Plekhg4
pleckstrin homology domain containing, family G (with RhoGef domain) member 4
chr7_+_54835959 0.07 ENSMUST00000082373.6
Luzp2
leucine zipper protein 2
chr18_-_42579652 0.07 ENSMUST00000054738.3
Gpr151
G protein-coupled receptor 151
chr6_-_54566484 0.07 ENSMUST00000019268.4
Scrn1
secernin 1
chr1_-_131097535 0.06 ENSMUST00000016672.4
Mapkapk2
MAP kinase-activated protein kinase 2
chr6_+_65381294 0.06 ENSMUST00000170608.1
C130060K24Rik
RIKEN cDNA C130060K24 gene
chr7_-_104164812 0.05 ENSMUST00000154555.1
ENSMUST00000051137.8
E030002O03Rik
RIKEN cDNA E030002O03 gene
chr11_-_107337556 0.05 ENSMUST00000040380.6
Pitpnc1
phosphatidylinositol transfer protein, cytoplasmic 1
chrX_+_151047170 0.03 ENSMUST00000026296.7
Fgd1
FYVE, RhoGEF and PH domain containing 1
chr1_-_136260873 0.02 ENSMUST00000086395.5
Gpr25
G protein-coupled receptor 25

Network of associatons between targets according to the STRING database.

First level regulatory network of Mafa

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 10.1 GO:1990535 negative regulation of NAD(P)H oxidase activity(GO:0033861) neuron projection maintenance(GO:1990535)
0.6 10.7 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.5 1.6 GO:0006507 GPI anchor release(GO:0006507)
0.4 2.1 GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342)
0.4 1.6 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.4 2.2 GO:1904075 regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.3 1.0 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.2 1.0 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.2 1.1 GO:0048104 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.2 1.5 GO:0098728 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) positive regulation of NK T cell differentiation(GO:0051138) germline stem cell asymmetric division(GO:0098728)
0.2 1.8 GO:0021940 positive regulation of cerebellar granule cell precursor proliferation(GO:0021940)
0.2 0.5 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.1 1.9 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 1.9 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.1 0.5 GO:0035582 sequestering of BMP in extracellular matrix(GO:0035582)
0.1 0.4 GO:0036269 swimming behavior(GO:0036269)
0.1 0.6 GO:0034436 glycoprotein transport(GO:0034436)
0.1 0.6 GO:0031443 fast-twitch skeletal muscle fiber contraction(GO:0031443)
0.1 0.5 GO:0046707 IDP metabolic process(GO:0046707) IDP catabolic process(GO:0046709)
0.1 0.4 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.1 0.9 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.1 0.4 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.7 GO:0060406 positive regulation of penile erection(GO:0060406)
0.1 0.7 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.1 1.0 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.1 0.2 GO:0030719 oocyte construction(GO:0007308) oocyte axis specification(GO:0007309) oocyte anterior/posterior axis specification(GO:0007314) pole plasm assembly(GO:0007315) maternal determination of anterior/posterior axis, embryo(GO:0008358) P granule organization(GO:0030719)
0.1 1.3 GO:0008272 sulfate transport(GO:0008272)
0.1 0.9 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.1 0.3 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 8.9 GO:0015758 glucose transport(GO:0015758)
0.0 0.8 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.3 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.7 GO:0033603 positive regulation of dopamine secretion(GO:0033603)
0.0 0.5 GO:0070444 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.0 0.4 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.0 0.4 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.3 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.1 GO:0046049 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0 1.7 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.0 2.1 GO:0048663 neuron fate commitment(GO:0048663)
0.0 0.4 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.0 4.1 GO:0043401 steroid hormone mediated signaling pathway(GO:0043401)
0.0 1.8 GO:0006821 chloride transport(GO:0006821)
0.0 0.2 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.1 GO:0044351 macropinocytosis(GO:0044351)
0.0 0.4 GO:0071480 cellular response to gamma radiation(GO:0071480)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 10.7 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.4 10.1 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.3 1.1 GO:0060187 cell pole(GO:0060187)
0.2 2.2 GO:0042567 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867) insulin-like growth factor ternary complex(GO:0042567)
0.1 0.4 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1 0.3 GO:0044302 dentate gyrus mossy fiber(GO:0044302)
0.1 0.6 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.1 1.9 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 0.7 GO:0005883 neurofilament(GO:0005883)
0.1 0.7 GO:0042587 glycogen granule(GO:0042587)
0.1 0.6 GO:0034385 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.1 0.4 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 1.6 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 2.1 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.5 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 1.2 GO:0005771 multivesicular body(GO:0005771)
0.0 0.3 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 1.4 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.3 GO:0001520 outer dense fiber(GO:0001520)
0.0 5.6 GO:0030141 secretory granule(GO:0030141)
0.0 1.5 GO:0017053 transcriptional repressor complex(GO:0017053)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.1 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.4 21.2 GO:0005158 insulin receptor binding(GO:0005158)
0.3 2.0 GO:0004065 arylsulfatase activity(GO:0004065)
0.2 1.1 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.2 0.6 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189) glycoprotein transporter activity(GO:0034437)
0.2 1.6 GO:0004630 phospholipase D activity(GO:0004630)
0.2 0.5 GO:0031686 uridine nucleotide receptor activity(GO:0015065) A1 adenosine receptor binding(GO:0031686) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.1 0.8 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 1.5 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 0.4 GO:0070991 medium-chain-acyl-CoA dehydrogenase activity(GO:0070991)
0.1 0.4 GO:0005176 ErbB-2 class receptor binding(GO:0005176) acetylcholine receptor activator activity(GO:0030549)
0.1 0.5 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.1 0.4 GO:0070728 leucine binding(GO:0070728)
0.1 2.6 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 1.9 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 1.8 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.5 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0 0.2 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.3 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.0 1.0 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.7 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.6 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.3 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.1 GO:0004849 uridine kinase activity(GO:0004849)
0.0 1.3 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.9 GO:0002039 p53 binding(GO:0002039)
0.0 11.3 GO:0008134 transcription factor binding(GO:0008134)
0.0 1.5 GO:0008528 G-protein coupled peptide receptor activity(GO:0008528)
0.0 0.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.3 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 2.2 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 2.2 PID IGF1 PATHWAY IGF1 pathway
0.0 4.5 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.4 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.5 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.3 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.5 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.3 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 1.0 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 2.6 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.1 2.3 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 4.8 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.4 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 1.8 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.5 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.4 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.4 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.3 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.1 REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION Genes involved in Nuclear Events (kinase and transcription factor activation)