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GSE58827: Dynamics of the Mouse Liver

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Results for Mafb

Z-value: 1.03

Motif logo

Transcription factors associated with Mafb

Gene Symbol Gene ID Gene Info
ENSMUSG00000074622.3 v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Mafbmm10_v2_chr2_-_160367057_1603670730.299.0e-02Click!

Activity profile of Mafb motif

Sorted Z-values of Mafb motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_67277124 9.76 ENSMUST00000019625.5
myosin, heavy polypeptide 8, skeletal muscle, perinatal
chr16_-_36367623 8.50 ENSMUST00000096089.2
cDNA sequence BC100530
chr3_-_92588982 8.23 ENSMUST00000098888.5
sperm mitochondria-associated cysteine-rich protein
chr16_-_36455378 8.05 ENSMUST00000068182.2
stefin A3
chr12_-_114060315 7.88 ENSMUST00000103469.2
immunoglobulin heavy variable V14-3
chr16_+_36156801 7.55 ENSMUST00000079184.4
stefin A2 like 1
chr6_+_41392356 7.00 ENSMUST00000049079.7
predicted gene 5771
chr16_+_36210403 6.38 ENSMUST00000089628.3
predicted gene 5416
chr10_+_79886302 5.94 ENSMUST00000046091.5
elastase, neutrophil expressed
chr10_+_75573448 5.83 ENSMUST00000006508.3
gamma-glutamyltransferase 1
chr16_-_16863817 5.45 ENSMUST00000124890.1
immunoglobulin lambda-like polypeptide 1
chr6_+_41458923 4.62 ENSMUST00000031910.7
protease, serine, 1 (trypsin 1)
chr1_+_174172738 4.38 ENSMUST00000027817.7
spectrin alpha, erythrocytic 1
chr16_-_16863975 4.36 ENSMUST00000100136.3
immunoglobulin lambda-like polypeptide 1
chr11_+_115877497 4.29 ENSMUST00000144032.1
myosin XVB
chr11_-_102925086 4.04 ENSMUST00000021311.9
kinesin family member 18B
chr14_+_80000292 3.98 ENSMUST00000088735.3
olfactomedin 4
chr10_-_88605017 3.95 ENSMUST00000119185.1
ENSMUST00000121629.1
myosin binding protein C, slow-type
chrX_-_93832106 3.66 ENSMUST00000045748.6
pyruvate dehydrogenase kinase, isoenzyme 3
chr1_-_132390301 3.61 ENSMUST00000132435.1
transmembrane and coiled-coil domains 2
chr2_+_164948219 3.60 ENSMUST00000017881.2
matrix metallopeptidase 9
chr7_-_135716374 3.27 ENSMUST00000033310.7
antigen identified by monoclonal antibody Ki 67
chr14_+_65266701 3.27 ENSMUST00000169656.1
F-box protein 16
chr7_+_35449035 3.19 ENSMUST00000118969.1
ENSMUST00000118383.1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 9
chrX_+_157699113 3.17 ENSMUST00000112521.1
small muscle protein, X-linked
chr2_-_127831817 2.80 ENSMUST00000028858.7
budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae)
chrX_+_49463926 2.74 ENSMUST00000130558.1
Rho GTPase activating protein 36
chr5_-_107726017 2.73 ENSMUST00000159263.2
growth factor independent 1
chr2_+_152847993 2.69 ENSMUST00000028969.8
TPX2, microtubule-associated protein homolog (Xenopus laevis)
chr2_-_180642681 2.68 ENSMUST00000037877.10
transcription factor-like 5 (basic helix-loop-helix)
chr7_-_4397705 2.62 ENSMUST00000108590.2
glycoprotein 6 (platelet)
chr7_+_45554893 2.52 ENSMUST00000107752.3
hydroxysteroid (17-beta) dehydrogenase 14
chrX_-_162964557 2.49 ENSMUST00000038769.2
S100 calcium binding protein G
chr5_+_140505550 2.45 ENSMUST00000043050.8
ENSMUST00000124142.1
carbohydrate sulfotransferase 12
chr2_+_152847961 2.45 ENSMUST00000164120.1
ENSMUST00000178997.1
ENSMUST00000109816.1
TPX2, microtubule-associated protein homolog (Xenopus laevis)
chr7_+_142460834 2.40 ENSMUST00000018963.4
ENSMUST00000105967.1
lymphocyte specific 1
chr6_+_40964760 2.40 ENSMUST00000076638.5
RIKEN cDNA 1810009J06 gene
chr7_+_142460809 2.36 ENSMUST00000105968.1
lymphocyte specific 1
chr11_-_73138245 2.25 ENSMUST00000052140.2
germ cell-specific gene 2
chr8_-_25091341 2.24 ENSMUST00000125466.1
pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2
chr3_+_105870858 2.16 ENSMUST00000164730.1
adenosine A3 receptor
chr2_-_84822546 2.12 ENSMUST00000028471.5
smoothelin-like 1
chr17_-_15041457 2.07 ENSMUST00000097400.4
ENSMUST00000097398.4
ENSMUST00000040746.6
predicted gene 3448
t-complex-associated testis expressed 3
chr3_+_157566868 2.05 ENSMUST00000041175.6
ENSMUST00000173533.1
prostaglandin E receptor 3 (subtype EP3)
chr10_-_62379852 2.02 ENSMUST00000143236.1
ENSMUST00000133429.1
ENSMUST00000132926.1
ENSMUST00000116238.2
hexokinase 1
chr10_+_70204675 2.00 ENSMUST00000020090.1
RIKEN cDNA 2310015B20 gene
chr6_+_48860339 1.98 ENSMUST00000101425.3
predicted gene 7932
chr8_+_72189613 1.98 ENSMUST00000072097.6
hematopoietic SH2 domain containing
chr12_+_117843489 1.97 ENSMUST00000021592.9
cell division cycle associated 7 like
chr17_-_14978812 1.97 ENSMUST00000097399.4
predicted gene 3417
chr14_+_118787894 1.91 ENSMUST00000047761.6
ENSMUST00000071546.7
claudin 10
chr17_+_26917091 1.90 ENSMUST00000078961.4
kinesin family member C5B
chr7_+_35449154 1.84 ENSMUST00000032703.9
solute carrier family 7 (cationic amino acid transporter, y+ system), member 9
chr7_+_46861203 1.84 ENSMUST00000014545.4
lactate dehydrogenase C
chr9_-_77347816 1.77 ENSMUST00000184138.1
ENSMUST00000184006.1
ENSMUST00000185144.1
ENSMUST00000034910.9
muscular LMNA-interacting protein
chr8_-_85119637 1.77 ENSMUST00000098550.3
zinc finger protein 791
chr6_-_136401830 1.74 ENSMUST00000058713.7
RIKEN cDNA E330021D16 gene
chr9_-_77347787 1.73 ENSMUST00000184848.1
ENSMUST00000184415.1
muscular LMNA-interacting protein
chr6_+_145145473 1.72 ENSMUST00000156849.1
ENSMUST00000132948.1
lymphoid-restricted membrane protein
chr14_-_19977151 1.71 ENSMUST00000055100.7
ENSMUST00000162425.1
guanine nucleotide binding protein (G protein), gamma 2
chr14_-_19977040 1.71 ENSMUST00000159028.1
guanine nucleotide binding protein (G protein), gamma 2
chr8_+_120002720 1.70 ENSMUST00000108972.3
cysteine-rich secretory protein LCCL domain containing 2
chr1_+_57845534 1.68 ENSMUST00000169772.1
spermatogenesis associated, serine-rich 2-like
chr8_+_70152754 1.68 ENSMUST00000072500.6
ENSMUST00000164040.1
ENSMUST00000110146.2
ENSMUST00000110143.1
ENSMUST00000110141.2
ENSMUST00000110140.1
RIKEN cDNA 2310045N01 gene
myocyte enhancer factor 2B
chr11_+_62574523 1.66 ENSMUST00000018651.7
transient receptor potential cation channel, subfamily V, member 2
chr18_+_53551594 1.64 ENSMUST00000115398.1
PR domain containing 6
chr9_+_45403138 1.64 ENSMUST00000041005.5
FXYD domain-containing ion transport regulator 2
chr6_-_87981482 1.62 ENSMUST00000056403.5
H1 histone family, member X
chr11_+_46055973 1.57 ENSMUST00000011400.7
a disintegrin and metallopeptidase domain 19 (meltrin beta)
chr6_-_83033422 1.56 ENSMUST00000089651.5
docking protein 1
chr2_+_105130883 1.52 ENSMUST00000111098.1
ENSMUST00000111099.1
Wilms tumor 1 homolog
chr2_+_157456917 1.51 ENSMUST00000109529.1
Rous sarcoma oncogene
chr2_-_33131645 1.47 ENSMUST00000133135.1
GTPase activating RANGAP domain-like 3
chr17_-_28942255 1.47 ENSMUST00000051526.4
peroxisomal, testis specific 1
chr15_-_56694525 1.45 ENSMUST00000050544.7
hyaluronan synthase 2
chr13_+_19214103 1.44 ENSMUST00000103558.1
T cell receptor gamma, constant 1
chr5_+_141856692 1.43 ENSMUST00000074546.6
sidekick homolog 1 (chicken)
chr13_-_68999518 1.43 ENSMUST00000022013.7
adenylate cyclase 2
chr6_-_56369625 1.41 ENSMUST00000170774.1
ENSMUST00000168944.1
ENSMUST00000166890.1
phosphodiesterase 1C
chr2_+_25289899 1.40 ENSMUST00000028337.6
leucine rich repeat containing 26
chr11_+_117782076 1.39 ENSMUST00000127080.1
transmembrane channel-like gene family 8
chr3_+_103074009 1.38 ENSMUST00000090715.6
adenosine monophosphate deaminase 1
chr7_-_19950729 1.37 ENSMUST00000043440.6
immunoglobulin superfamily, member 23
chr3_+_28781305 1.37 ENSMUST00000060500.7
eukaryotic translation initiation factor 5A2
chr2_-_79428891 1.32 ENSMUST00000143974.1
ceramide kinase-like
chr10_+_78780470 1.32 ENSMUST00000005490.8
solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
chr7_+_17087934 1.31 ENSMUST00000152671.1
pregnancy specific glycoprotein 16
chr13_-_49248663 1.31 ENSMUST00000135784.1
ENSMUST00000021816.5
sushi domain containing 3
chr2_+_105126505 1.30 ENSMUST00000143043.1
Wilms tumor 1 homolog
chr2_+_148835140 1.30 ENSMUST00000028935.3
cystatin 9
chr19_-_5986143 1.30 ENSMUST00000041827.7
solute carrier family 22 (organic anion transporter), member 20
chr11_+_82101836 1.30 ENSMUST00000000194.3
chemokine (C-C motif) ligand 12
chr3_-_95251148 1.29 ENSMUST00000125515.2
ENSMUST00000107195.2
BCL2/adenovirus E1B 19kD interacting protein like
chr5_+_112255813 1.27 ENSMUST00000031286.6
ENSMUST00000131673.1
ENSMUST00000112375.1
crystallin, beta B1
chrX_-_8145679 1.25 ENSMUST00000115619.1
ENSMUST00000115617.3
ENSMUST00000040010.3
RNA binding motif protein 3
chr8_+_119700009 1.25 ENSMUST00000095171.3
ATPase, Ca++ transporting, type 2C, member 2
chr19_+_6384395 1.22 ENSMUST00000035269.8
ENSMUST00000113483.1
muscle glycogen phosphorylase
chr19_+_46056539 1.21 ENSMUST00000111899.1
ENSMUST00000099392.3
ENSMUST00000062322.4
peroxisome proliferative activated receptor, gamma, coactivator-related 1
chr16_-_36131156 1.18 ENSMUST00000161638.1
ENSMUST00000096090.2
cystatin A
chr14_-_20452217 1.17 ENSMUST00000144797.1
ENSMUST00000151077.1
ENSMUST00000022348.7
ENSMUST00000056073.6
ENSMUST00000022349.6
tetratricopeptide repeat domain 18
chr11_+_119229092 1.17 ENSMUST00000053440.7
coiled-coil domain containing 40
chr6_+_72097561 1.13 ENSMUST00000069994.4
ENSMUST00000114112.1
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr1_+_71652837 1.10 ENSMUST00000097699.2
apolipoprotein L 7d
chr6_-_25690729 1.10 ENSMUST00000054867.6
G protein-coupled receptor 37
chr1_+_75360321 1.09 ENSMUST00000027409.9
desmin
chr3_+_105870898 1.09 ENSMUST00000010279.5
adenosine A3 receptor
chr7_+_44012672 1.08 ENSMUST00000048945.4
kallikrein 1-related petidase b26
chr7_-_110862944 1.07 ENSMUST00000033050.3
lymphatic vessel endothelial hyaluronan receptor 1
chr18_-_62179948 1.04 ENSMUST00000053640.3
adrenergic receptor, beta 2
chr12_+_107488632 1.04 ENSMUST00000082269.2
RIKEN cDNA 3110018I06 gene
chr17_-_17883920 1.03 ENSMUST00000061516.7
formyl peptide receptor 1
chr4_-_132351636 0.98 ENSMUST00000105951.1
regulator of chromosome condensation 1
chr11_+_50357759 0.98 ENSMUST00000052596.2
chibby homolog 3 (Drosophila)
chr11_-_83645621 0.97 ENSMUST00000182502.1
ribosomal protein L9, pseudogene 1
chr6_+_120773633 0.97 ENSMUST00000112682.2
solute carrier family 25 (mitochondrial carrier), member 18
chr6_+_29279587 0.96 ENSMUST00000167131.1
family with sequence similarity 71, member F2
chr12_+_85746539 0.95 ENSMUST00000040461.3
major facilitator superfamily domain containing 7C
chr5_-_137149320 0.95 ENSMUST00000041226.8
mucin 3, intestinal
chr17_+_34398802 0.92 ENSMUST00000114175.1
ENSMUST00000078615.5
ENSMUST00000139063.1
ENSMUST00000097348.2
cDNA sequence BC051142
chr5_+_140735526 0.92 ENSMUST00000120630.2
archaelysin family metallopeptidase 1
chr3_+_103074035 0.88 ENSMUST00000176440.1
adenosine monophosphate deaminase 1
chr4_-_156255327 0.88 ENSMUST00000179919.1
sterile alpha motif domain containing 11
chr5_+_65934922 0.88 ENSMUST00000153624.1
cholinergic receptor, nicotinic, alpha polypeptide 9
chr15_+_82252397 0.88 ENSMUST00000136948.1
RIKEN cDNA 1500009C09 gene
chr19_+_44293676 0.87 ENSMUST00000026221.5
stearoyl-Coenzyme A desaturase 2
chr1_-_161979636 0.87 ENSMUST00000162676.1
RIKEN cDNA 4930558K02 gene
chr9_-_111690313 0.87 ENSMUST00000035083.7
src homology three (SH3) and cysteine rich domain
chr9_-_77347889 0.87 ENSMUST00000185039.1
muscular LMNA-interacting protein
chr13_-_106847267 0.86 ENSMUST00000057427.4
leucine rich repeat containing 70
chr15_-_89410230 0.86 ENSMUST00000109314.2
synaptonemal complex central element protein 3
chr10_-_129902726 0.86 ENSMUST00000071557.1
olfactory receptor 815
chr9_+_95637601 0.84 ENSMUST00000015498.8
procollagen C-endopeptidase enhancer 2
chr8_-_123983120 0.84 ENSMUST00000075578.6
ATP-binding cassette, sub-family B (MDR/TAP), member 10
chr8_+_69808672 0.83 ENSMUST00000036074.8
ENSMUST00000123453.1
Gem-interacting protein
chr2_-_31116289 0.83 ENSMUST00000149196.1
formin binding protein 1
chr11_-_114934351 0.82 ENSMUST00000106581.1
ENSMUST00000074300.2
CD300 antigen like family member B
chr13_-_62607499 0.81 ENSMUST00000091563.4
RIKEN cDNA 6720489N17 gene
chr2_-_69206133 0.81 ENSMUST00000112320.1
SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr7_+_30493622 0.81 ENSMUST00000058280.6
ENSMUST00000133318.1
ENSMUST00000142575.1
ENSMUST00000131040.1
proline dehydrogenase (oxidase) 2
chr2_-_69206146 0.81 ENSMUST00000127243.1
ENSMUST00000149643.1
ENSMUST00000167875.2
ENSMUST00000005365.8
SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chrX_+_153139941 0.80 ENSMUST00000039720.4
ENSMUST00000144175.2
Ras-related GTP binding B
chr6_-_129507107 0.79 ENSMUST00000183258.1
ENSMUST00000182784.1
ENSMUST00000032265.6
ENSMUST00000162815.1
oxidized low density lipoprotein (lectin-like) receptor 1
chr8_+_84969587 0.78 ENSMUST00000109734.1
ENSMUST00000005292.8
peroxiredoxin 2
chr1_+_75382114 0.78 ENSMUST00000113590.1
ENSMUST00000148515.1
SPEG complex locus
chr11_-_109473598 0.76 ENSMUST00000070152.5
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr7_-_46672537 0.74 ENSMUST00000049298.7
tryptophan hydroxylase 1
chr6_+_149309444 0.73 ENSMUST00000100765.4
RIKEN cDNA 2810474O19 gene
chr17_-_35702297 0.73 ENSMUST00000135078.1
discoidin domain receptor family, member 1
chr14_+_22019833 0.70 ENSMUST00000159777.1
ENSMUST00000162540.1
RIKEN cDNA 1700112E06 gene
chr14_+_51552790 0.70 ENSMUST00000096170.4
predicted gene 5622
chr16_+_35770382 0.69 ENSMUST00000023555.4
Hspb associated protein 1
chr5_-_103629279 0.68 ENSMUST00000031263.1
solute carrier family 10 (sodium/bile acid cotransporter family), member 6
chr2_+_181319714 0.68 ENSMUST00000098971.4
ENSMUST00000054622.8
ENSMUST00000108814.1
ENSMUST00000048608.9
ENSMUST00000108815.1
regulator of telomere elongation helicase 1
chr3_+_90266507 0.68 ENSMUST00000098914.3
DENN/MADD domain containing 4B
chr17_+_22689771 0.67 ENSMUST00000055305.8
predicted gene 9805
chr3_-_95251049 0.65 ENSMUST00000098871.4
BCL2/adenovirus E1B 19kD interacting protein like
chr12_-_24493656 0.65 ENSMUST00000073088.2
predicted pseudogene 16372
chr2_-_166713758 0.64 ENSMUST00000036719.5
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
chr11_+_75651504 0.64 ENSMUST00000069057.6
myosin IC
chr7_-_127875633 0.64 ENSMUST00000106261.1
ENSMUST00000144721.1
zinc finger protein 668
chr17_+_66111605 0.64 ENSMUST00000116556.2
WAS protein family homolog
chr17_-_6477102 0.63 ENSMUST00000167717.2
transmembrane protein 181B, pseudogene
chr2_+_181319806 0.63 ENSMUST00000153112.1
regulator of telomere elongation helicase 1
chr9_-_48911067 0.63 ENSMUST00000003826.7
5-hydroxytryptamine (serotonin) receptor 3A
chr6_+_149309391 0.62 ENSMUST00000130664.1
ENSMUST00000046689.6
RIKEN cDNA 2810474O19 gene
chr12_+_104263117 0.62 ENSMUST00000109958.2
serine (or cysteine) peptidase inhibitor, clade A, member 3I
chr18_-_64489042 0.62 ENSMUST00000025484.7
ferrochelatase
chr2_-_163645125 0.62 ENSMUST00000017851.3
serine incorporator 3
chr6_+_121210731 0.62 ENSMUST00000032233.7
tubulin, alpha 8
chr2_-_84425258 0.60 ENSMUST00000074262.2
calcitonin receptor-like
chr10_-_80906410 0.60 ENSMUST00000105332.2
lamin B2
chr9_+_102506072 0.60 ENSMUST00000039390.4
kyphoscoliosis peptidase
chr5_-_35525691 0.60 ENSMUST00000038676.5
carboxypeptidase Z
chr2_+_32621750 0.59 ENSMUST00000113278.2
adenylate kinase 1
chr4_+_132351768 0.59 ENSMUST00000172202.1
predicted gene, 17300
chr1_-_120270253 0.58 ENSMUST00000112639.1
STEAP family member 3
chr12_+_34984748 0.57 ENSMUST00000134550.2
phosphoribosyl pyrophosphate synthetase 1-like 1
chr7_+_121083322 0.57 ENSMUST00000047025.8
ENSMUST00000170106.1
otoancorin
chr10_+_22645011 0.57 ENSMUST00000042261.4
solute carrier family 2 (facilitated glucose transporter), member 12
chr18_-_61707583 0.56 ENSMUST00000025472.1
prenylcysteine oxidase 1 like
chr17_+_6270475 0.56 ENSMUST00000088940.4
transmembrane protein 181A
chr11_+_106374820 0.55 ENSMUST00000106816.1
RIKEN cDNA 2310007L24 gene
chr14_+_66784523 0.55 ENSMUST00000071522.2
predicted gene 10032
chr10_-_53647080 0.55 ENSMUST00000169866.1
family with sequence similarity 184, member A
chr10_+_116143881 0.54 ENSMUST00000105271.2
protein tyrosine phosphatase, receptor type, R
chr11_-_103363431 0.54 ENSMUST00000092557.5
Rho GTPase activating protein 27
chr8_-_24725762 0.53 ENSMUST00000171438.1
ENSMUST00000171611.1
ENSMUST00000033958.7
a disintegrin and metallopeptidase domain 3 (cyritestin)
chr5_+_110839973 0.53 ENSMUST00000066160.1
checkpoint kinase 2
chr7_+_46861253 0.51 ENSMUST00000148565.1
lactate dehydrogenase C
chr17_-_71460395 0.50 ENSMUST00000180522.1
predicted gene 4707
chr8_-_12672135 0.50 ENSMUST00000000776.8
tubulin, gamma complex associated protein 3
chr9_+_38877126 0.50 ENSMUST00000078289.2
olfactory receptor 926
chr2_+_36049453 0.49 ENSMUST00000028256.4
MORN repeat containing 5
chr15_-_25413752 0.49 ENSMUST00000058845.7
brain abundant, membrane attached signal protein 1
chr5_+_30013141 0.49 ENSMUST00000026845.7
interleukin 6
chr10_-_42276688 0.49 ENSMUST00000175881.1
ENSMUST00000056974.3
forkhead box O3
chr9_-_121995962 0.48 ENSMUST00000084743.5
protein O-linked mannose beta 1,4-N-acetylglucosaminyltransferase 2
chr7_-_100964371 0.48 ENSMUST00000060174.4
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr5_-_137533297 0.48 ENSMUST00000111020.1
ENSMUST00000111023.1
guanine nucleotide binding protein (G protein), beta 2
chr1_-_173766876 0.47 ENSMUST00000111214.2
interferon activated gene 204

Network of associatons between targets according to the STRING database.

First level regulatory network of Mafb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 6.4 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
1.7 5.0 GO:0015811 L-cystine transport(GO:0015811)
1.2 3.6 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
1.2 8.1 GO:0007341 penetration of zona pellucida(GO:0007341)
1.1 3.3 GO:1990705 cholangiocyte proliferation(GO:1990705)
0.9 2.8 GO:0072299 negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302) regulation of metanephric ureteric bud development(GO:2001074) positive regulation of metanephric ureteric bud development(GO:2001076)
0.9 2.8 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.9 3.7 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.8 2.5 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.7 5.8 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.7 3.5 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902)
0.7 2.1 GO:1903116 gastrin-induced gastric acid secretion(GO:0001698) positive regulation of actin filament-based movement(GO:1903116) regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764) negative regulation of forebrain neuron differentiation(GO:2000978)
0.6 9.8 GO:0030049 muscle filament sliding(GO:0030049)
0.5 2.7 GO:0010956 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) regulation of interleukin-6-mediated signaling pathway(GO:0070103)
0.5 2.6 GO:0019516 lactate oxidation(GO:0019516)
0.5 1.5 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.4 17.7 GO:0006910 phagocytosis, recognition(GO:0006910)
0.3 1.3 GO:1902990 mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.3 1.3 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.3 0.8 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.3 1.0 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025) diaphragm contraction(GO:0002086)
0.3 2.5 GO:0002349 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.3 2.3 GO:0032264 IMP salvage(GO:0032264)
0.2 3.9 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.2 1.4 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.2 0.9 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.2 1.7 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.2 1.2 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.2 0.6 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.2 1.6 GO:0040009 regulation of growth rate(GO:0040009)
0.2 0.5 GO:0098763 mitotic cell cycle phase(GO:0098763)
0.2 1.0 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.2 3.3 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.2 1.3 GO:0098712 L-glutamate import across plasma membrane(GO:0098712)
0.2 0.6 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.1 0.6 GO:0009405 pathogenesis(GO:0009405)
0.1 5.1 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.1 0.6 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.1 0.6 GO:0009597 detection of virus(GO:0009597)
0.1 0.2 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.1 1.1 GO:0045915 positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
0.1 1.6 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.1 0.6 GO:1902167 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902167)
0.1 0.7 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 0.8 GO:1901300 positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300)
0.1 0.6 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 1.4 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.1 0.6 GO:0006172 ADP biosynthetic process(GO:0006172)
0.1 1.1 GO:0002035 brain renin-angiotensin system(GO:0002035)
0.1 4.9 GO:0051693 actin filament capping(GO:0051693)
0.1 0.3 GO:0003220 left ventricular cardiac muscle tissue morphogenesis(GO:0003220)
0.1 0.5 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.1 0.5 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.1 4.7 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1 0.8 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.1 0.3 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 11.6 GO:0007586 digestion(GO:0007586)
0.1 0.3 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.1 3.6 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.1 0.7 GO:0042427 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.1 0.4 GO:0035617 stress granule disassembly(GO:0035617)
0.1 1.3 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.1 2.1 GO:0014823 response to activity(GO:0014823)
0.1 0.2 GO:0042275 error-free postreplication DNA repair(GO:0042275)
0.1 1.4 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 0.1 GO:0019389 glucuronoside metabolic process(GO:0019389)
0.1 0.6 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 0.5 GO:0051415 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.1 0.5 GO:0030321 transepithelial chloride transport(GO:0030321)
0.1 1.2 GO:0005980 glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.1 0.5 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.1 0.8 GO:0002536 respiratory burst involved in inflammatory response(GO:0002536)
0.1 1.1 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.1 4.0 GO:0007019 microtubule depolymerization(GO:0007019)
0.1 1.4 GO:0048148 behavioral response to cocaine(GO:0048148)
0.1 0.4 GO:0070309 tubulin complex assembly(GO:0007021) lens fiber cell morphogenesis(GO:0070309)
0.1 0.5 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.1 2.9 GO:0090280 positive regulation of calcium ion import(GO:0090280)
0.0 0.2 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760) post-embryonic hemopoiesis(GO:0035166)
0.0 0.9 GO:0032460 negative regulation of protein oligomerization(GO:0032460)
0.0 2.2 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.0 0.2 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.0 2.4 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.0 0.3 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.8 GO:0033005 positive regulation of mast cell activation(GO:0033005)
0.0 2.6 GO:0007052 mitotic spindle organization(GO:0007052)
0.0 1.1 GO:0045109 intermediate filament organization(GO:0045109)
0.0 0.5 GO:0071361 cellular response to ethanol(GO:0071361)
0.0 0.9 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 1.4 GO:0019730 antimicrobial humoral response(GO:0019730)
0.0 0.5 GO:0061318 renal filtration cell differentiation(GO:0061318) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0 1.4 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.0 1.1 GO:0009409 response to cold(GO:0009409)
0.0 1.6 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0 0.5 GO:0035994 response to muscle stretch(GO:0035994)
0.0 0.1 GO:0072014 proximal tubule development(GO:0072014)
0.0 0.2 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.2 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.0 0.1 GO:0035826 rubidium ion transport(GO:0035826)
0.0 1.4 GO:0060325 face morphogenesis(GO:0060325)
0.0 1.1 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.1 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 0.2 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.0 0.1 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 0.3 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.2 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.0 0.9 GO:0035825 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.0 0.6 GO:0032414 positive regulation of ion transmembrane transporter activity(GO:0032414)
0.0 2.6 GO:0006941 striated muscle contraction(GO:0006941)
0.0 0.4 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.3 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.6 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.0 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.5 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 1.4 GO:0007338 single fertilization(GO:0007338)
0.0 0.2 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.1 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.0 0.4 GO:0042092 type 2 immune response(GO:0042092)
0.0 0.3 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.0 0.1 GO:0035635 entry of bacterium into host cell(GO:0035635) regulation of entry of bacterium into host cell(GO:2000535)
0.0 0.0 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.0 0.5 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 0.4 GO:0034113 heterotypic cell-cell adhesion(GO:0034113)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 9.2 GO:0005818 aster(GO:0005818)
1.0 17.7 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.7 4.4 GO:0032437 cuticular plate(GO:0032437)
0.7 2.8 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.5 3.2 GO:0005927 muscle tendon junction(GO:0005927)
0.4 2.1 GO:1990769 proximal neuron projection(GO:1990769)
0.4 9.8 GO:0032982 myosin filament(GO:0032982)
0.4 3.9 GO:0005859 muscle myosin complex(GO:0005859)
0.3 1.6 GO:0031262 Ndc80 complex(GO:0031262)
0.2 4.0 GO:0042581 specific granule(GO:0042581)
0.2 2.6 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.2 2.1 GO:0032584 growth cone membrane(GO:0032584)
0.2 0.6 GO:0045160 myosin I complex(GO:0045160)
0.2 0.8 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 1.1 GO:0045098 type III intermediate filament(GO:0045098)
0.1 2.5 GO:0001673 male germ cell nucleus(GO:0001673)
0.1 0.5 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.3 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.1 0.9 GO:0000801 central element(GO:0000801)
0.1 0.6 GO:0005638 lamin filament(GO:0005638)
0.1 2.1 GO:0031430 M band(GO:0031430)
0.1 0.3 GO:0008623 CHRAC(GO:0008623)
0.1 8.9 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 0.5 GO:0000923 equatorial microtubule organizing center(GO:0000923) polar microtubule(GO:0005827)
0.1 0.2 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.1 0.5 GO:0097470 ribbon synapse(GO:0097470)
0.1 3.3 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 1.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 1.8 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 1.5 GO:0097228 sperm principal piece(GO:0097228)
0.0 5.2 GO:0016605 PML body(GO:0016605)
0.0 0.6 GO:0001520 outer dense fiber(GO:0001520)
0.0 5.0 GO:0031526 brush border membrane(GO:0031526)
0.0 0.2 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.0 1.9 GO:0002102 podosome(GO:0002102)
0.0 0.4 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 2.3 GO:0005871 kinesin complex(GO:0005871)
0.0 0.2 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.5 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 1.3 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 5.9 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 3.7 GO:0031514 motile cilium(GO:0031514)
0.0 0.6 GO:0071010 U1 snRNP(GO:0005685) prespliceosome(GO:0071010)
0.0 3.8 GO:0000793 condensed chromosome(GO:0000793)
0.0 0.2 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.0 0.8 GO:0032592 integral component of mitochondrial membrane(GO:0032592)
0.0 0.2 GO:0031932 TORC2 complex(GO:0031932)
0.0 1.4 GO:0005643 nuclear pore(GO:0005643)
0.0 2.4 GO:0001650 fibrillar center(GO:0001650)
0.0 6.1 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.5 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 0.3 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.2 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.5 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.9 GO:0030315 T-tubule(GO:0030315)
0.0 0.5 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 3.7 GO:0016607 nuclear speck(GO:0016607)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.0 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.9 3.7 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.8 2.5 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.7 17.7 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.6 5.1 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.5 5.8 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.5 2.8 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.4 1.3 GO:0001729 ceramide kinase activity(GO:0001729)
0.4 1.7 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.4 2.8 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.4 2.6 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.4 1.5 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.4 2.5 GO:0005499 vitamin D binding(GO:0005499)
0.3 1.2 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.3 2.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.3 3.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.3 3.3 GO:0038064 collagen receptor activity(GO:0038064)
0.3 1.0 GO:0004939 beta-adrenergic receptor activity(GO:0004939) bradykinin receptor binding(GO:0031711)
0.3 2.3 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.2 0.9 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.2 5.6 GO:0000146 microfilament motor activity(GO:0000146)
0.2 0.6 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.2 3.9 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.2 0.6 GO:0030350 iron-responsive element binding(GO:0030350)
0.2 0.6 GO:0004948 calcitonin receptor activity(GO:0004948)
0.2 1.4 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.2 1.7 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.2 0.7 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.2 2.3 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.2 1.0 GO:0005124 scavenger receptor binding(GO:0005124)
0.2 1.0 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.2 5.8 GO:0001968 fibronectin binding(GO:0001968)
0.2 0.5 GO:0015065 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.2 3.4 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.2 1.5 GO:0071253 connexin binding(GO:0071253)
0.1 0.9 GO:0042731 PH domain binding(GO:0042731)
0.1 5.9 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 1.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 0.3 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.1 2.1 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.3 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.1 1.4 GO:0004016 adenylate cyclase activity(GO:0004016)
0.1 1.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 0.6 GO:0000293 ferric-chelate reductase activity(GO:0000293) cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 0.6 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.1 13.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 0.8 GO:0008430 selenium binding(GO:0008430)
0.1 0.2 GO:0015119 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1 6.4 GO:0003777 microtubule motor activity(GO:0003777)
0.1 0.5 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 1.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.5 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 1.2 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.8 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.1 1.1 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.6 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.1 GO:0035827 rubidium ion transmembrane transporter activity(GO:0035827)
0.0 0.4 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.6 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.9 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.4 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 1.9 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.5 GO:0031432 titin binding(GO:0031432)
0.0 1.2 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 1.6 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 1.1 GO:0008373 sialyltransferase activity(GO:0008373)
0.0 0.3 GO:0046790 virion binding(GO:0046790)
0.0 1.6 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 1.3 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 6.8 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 1.7 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 2.3 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.0 0.8 GO:0071949 FAD binding(GO:0071949)
0.0 0.6 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.0 0.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 1.0 GO:0001221 transcription cofactor binding(GO:0001221)
0.0 0.4 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.4 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.0 1.7 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 1.1 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.2 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.8 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.8 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.0 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
0.0 0.5 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 7.0 GO:0003779 actin binding(GO:0003779)
0.0 0.3 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.3 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.0 GO:0004568 chitinase activity(GO:0004568)
0.0 0.5 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 12.1 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.2 3.4 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 7.9 PID PLK1 PATHWAY PLK1 signaling events
0.1 4.8 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 1.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 3.0 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.5 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 1.0 PID ARF6 PATHWAY Arf6 signaling events
0.0 1.5 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.5 ST STAT3 PATHWAY STAT3 Pathway
0.0 2.2 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 2.8 PID P73PATHWAY p73 transcription factor network
0.0 1.1 PID AURORA B PATHWAY Aurora B signaling
0.0 2.2 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.4 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.5 PID ATM PATHWAY ATM pathway
0.0 0.6 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 3.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.0 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 2.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 14.2 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.3 14.8 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.3 3.7 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.2 2.1 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.2 3.6 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.1 2.5 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.1 5.0 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 6.1 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.1 2.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 2.5 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 4.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 1.4 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 1.5 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.1 0.6 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 0.5 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 1.2 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 0.7 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 1.3 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.1 0.5 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 2.3 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 1.4 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 2.0 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 4.4 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.5 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.3 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.7 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.8 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 1.3 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 1.0 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.6 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.6 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.8 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.4 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.5 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.5 REACTOME ION CHANNEL TRANSPORT Genes involved in Ion channel transport
0.0 0.2 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.4 REACTOME KINESINS Genes involved in Kinesins
0.0 0.6 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.4 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 1.0 REACTOME LATE PHASE OF HIV LIFE CYCLE Genes involved in Late Phase of HIV Life Cycle
0.0 0.2 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.8 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.0 0.8 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 0.3 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.5 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines