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GSE58827: Dynamics of the Mouse Liver

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Results for Mbd2

Z-value: 0.90

Motif logo

Transcription factors associated with Mbd2

Gene Symbol Gene ID Gene Info
ENSMUSG00000024513.10 methyl-CpG binding domain protein 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Mbd2mm10_v2_chr18_+_70568189_70568398-0.391.8e-02Click!

Activity profile of Mbd2 motif

Sorted Z-values of Mbd2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_137277489 1.95 ENSMUST00000045747.4
wingless-related MMTV integration site 4
chr4_-_149774238 1.86 ENSMUST00000105686.2
solute carrier family 25, member 33
chr5_-_135078224 1.79 ENSMUST00000067935.4
ENSMUST00000076203.2
vacuolar protein sorting 37D (yeast)
chr5_+_30588078 1.57 ENSMUST00000066295.2
potassium channel, subfamily K, member 3
chr2_-_24763047 1.52 ENSMUST00000100348.3
ENSMUST00000041342.5
ENSMUST00000114447.1
ENSMUST00000102939.2
ENSMUST00000070864.7
calcium channel, voltage-dependent, N type, alpha 1B subunit
chr17_+_83215271 1.51 ENSMUST00000170794.1
protein kinase domain containing, cytoplasmic
chr1_+_91801453 1.48 ENSMUST00000007949.3
twist basic helix-loop-helix transcription factor 2
chr11_+_85832551 1.33 ENSMUST00000000095.6
T-box 2
chr4_-_151861762 1.28 ENSMUST00000097774.2
calmodulin binding transcription activator 1
chr4_-_120747248 1.24 ENSMUST00000030376.7
potassium voltage-gated channel, subfamily Q, member 4
chr8_+_27085520 1.22 ENSMUST00000178514.1
ENSMUST00000033876.7
G protein-coupled receptor 124
chr11_-_75796048 1.20 ENSMUST00000021209.7
double C2, beta
chr11_-_102296618 1.15 ENSMUST00000107132.2
ENSMUST00000073234.2
ataxin 7-like 3
chr14_+_45219993 1.05 ENSMUST00000146150.1
G protein-coupled receptor 137C
chrX_+_152144240 1.00 ENSMUST00000168786.1
ENSMUST00000112605.1
ENSMUST00000112604.1
IQ motif and Sec7 domain 2
chr15_-_103366763 1.00 ENSMUST00000023128.6
integrin alpha 5 (fibronectin receptor alpha)
chr2_-_94406647 1.00 ENSMUST00000111237.2
ENSMUST00000094801.4
ENSMUST00000111238.1
tetratricopeptide repeat domain 17
chr11_-_98053415 0.99 ENSMUST00000017544.2
SH3 and cysteine rich domain 2
chr8_+_83997613 0.99 ENSMUST00000095228.3
sterile alpha motif domain containing 1
chr3_-_108226598 0.97 ENSMUST00000029486.7
ENSMUST00000156371.1
ENSMUST00000141387.1
synaptophysin-like 2
chr3_+_89773562 0.97 ENSMUST00000038356.8
ubiquitin-conjugating enzyme E2Q (putative) 1
chr11_+_7063423 0.97 ENSMUST00000020706.4
adenylate cyclase 1
chr17_+_34031787 0.97 ENSMUST00000044858.8
retinoid X receptor beta
chr13_+_46418266 0.96 ENSMUST00000037923.3
RNA binding motif protein 24
chr4_-_3938354 0.94 ENSMUST00000003369.3
pleiomorphic adenoma gene 1
chr2_-_35979624 0.93 ENSMUST00000028248.4
ENSMUST00000112976.2
tubulin tyrosine ligase-like family, member 11
chr12_-_85339346 0.93 ENSMUST00000040992.7
NIMA (never in mitosis gene a)-related expressed kinase 9
chr9_-_114390633 0.92 ENSMUST00000084881.4
cartilage associated protein
chr17_+_34032071 0.89 ENSMUST00000174299.1
ENSMUST00000173554.1
retinoid X receptor beta
chr4_+_154960915 0.86 ENSMUST00000049621.6
hairy and enhancer of split 5 (Drosophila)
chr15_-_76656905 0.84 ENSMUST00000176274.1
cysteine and histidine rich 1
chr9_+_95559817 0.83 ENSMUST00000079597.5
progestin and adipoQ receptor family member IX
chr11_-_77489666 0.80 ENSMUST00000037593.7
ENSMUST00000092892.3
ankyrin repeat domain 13b
chr11_-_106160101 0.78 ENSMUST00000045923.3
LIM domain containing 2
chr8_+_27085835 0.77 ENSMUST00000165366.2
G protein-coupled receptor 124
chr4_+_129985098 0.77 ENSMUST00000106017.1
ENSMUST00000121049.1
brain-specific angiogenesis inhibitor 2
chr6_-_87981482 0.76 ENSMUST00000056403.5
H1 histone family, member X
chr17_+_46161111 0.76 ENSMUST00000166563.1
GTP binding protein 2
chr7_+_126272589 0.75 ENSMUST00000056028.9
SH3-binding kinase 1
chr13_-_52981027 0.74 ENSMUST00000071065.7
nuclear factor, interleukin 3, regulated
chr15_+_87625214 0.71 ENSMUST00000068088.6
family with sequence similarity 19, member A5
chr19_-_4306214 0.70 ENSMUST00000171123.1
ENSMUST00000088737.4
adrenergic receptor kinase, beta 1
chr17_-_47924460 0.69 ENSMUST00000113262.1
forkhead box P4
chr17_-_47924400 0.69 ENSMUST00000113263.1
ENSMUST00000097311.2
forkhead box P4
chr2_+_174110340 0.69 ENSMUST00000044415.9
aminopeptidase-like 1
chr7_+_4690760 0.68 ENSMUST00000048248.7
BR serine/threonine kinase 1
chr7_+_29303958 0.67 ENSMUST00000049977.6
D4, zinc and double PHD fingers family 1
chr10_-_118868903 0.66 ENSMUST00000004281.8
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
chr18_-_58209926 0.65 ENSMUST00000025497.6
fibrillin 2
chr5_+_137288273 0.65 ENSMUST00000024099.4
ENSMUST00000085934.3
acetylcholinesterase
chr11_-_102447647 0.64 ENSMUST00000049057.4
family with sequence similarity 171, member A2
chr1_-_74885322 0.64 ENSMUST00000159232.1
ENSMUST00000068631.3
FEV (ETS oncogene family)
chr14_-_24245913 0.63 ENSMUST00000073687.6
ENSMUST00000090398.4
discs, large homolog 5 (Drosophila)
chr11_+_103171081 0.63 ENSMUST00000042286.5
formin-like 1
chr19_+_6241668 0.63 ENSMUST00000045351.6
autophagy related 2A
chr14_+_20707548 0.62 ENSMUST00000022358.7
zinc finger SWIM-type containing 8
chr17_-_45549655 0.61 ENSMUST00000180252.1
transmembrane protein 151B
chr6_-_124756478 0.61 ENSMUST00000088357.5
atrophin 1
chr4_-_151861698 0.59 ENSMUST00000049790.7
calmodulin binding transcription activator 1
chr14_+_57524734 0.59 ENSMUST00000089494.4
interleukin 17D
chr11_-_98018308 0.59 ENSMUST00000107561.2
calcium channel, voltage-dependent, beta 1 subunit
chr16_-_18629864 0.58 ENSMUST00000096987.5
septin 5
chr7_-_65156416 0.58 ENSMUST00000148459.1
ENSMUST00000119118.1
family with sequence similarity 189, member A1
chr4_-_126753372 0.58 ENSMUST00000030637.7
ENSMUST00000106116.1
neurochondrin
chr7_+_99381495 0.58 ENSMUST00000037528.8
glycerophosphodiester phosphodiesterase domain containing 5
chr15_-_73184840 0.58 ENSMUST00000044113.10
argonaute RISC catalytic subunit 2
chr17_-_29237759 0.57 ENSMUST00000137727.1
ENSMUST00000024805.7
copine V
chr7_+_3332918 0.57 ENSMUST00000092891.4
calcium channel, voltage-dependent, gamma subunit 7
chr5_+_114568016 0.57 ENSMUST00000043650.7
family with sequence similarity 222, member A
chr11_-_106920681 0.57 ENSMUST00000103067.3
SMAD specific E3 ubiquitin protein ligase 2
chr7_+_4690604 0.56 ENSMUST00000120836.1
BR serine/threonine kinase 1
chr17_-_34031684 0.56 ENSMUST00000169397.1
solute carrier family 39 (zinc transporter), member 7
chr9_-_108190352 0.55 ENSMUST00000035208.7
bassoon
chr11_+_97663366 0.55 ENSMUST00000044730.5
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr5_-_136244865 0.55 ENSMUST00000005188.9
SH2B adaptor protein 2
chr9_+_65101453 0.55 ENSMUST00000077696.6
ENSMUST00000035499.4
ENSMUST00000166273.1
immunoglobulin superfamily, DCC subclass, member 4
chrX_-_94123087 0.55 ENSMUST00000113925.1
zinc finger protein X-linked
chr4_+_155734800 0.54 ENSMUST00000147721.1
ENSMUST00000127188.2
transmembrane protein 240
chr4_+_133240778 0.54 ENSMUST00000030677.6
mitogen-activated protein kinase kinase kinase 6
chr12_+_87147703 0.54 ENSMUST00000063117.8
glutathione transferase zeta 1 (maleylacetoacetate isomerase)
chr4_-_151861667 0.54 ENSMUST00000169423.2
calmodulin binding transcription activator 1
chr15_-_41869703 0.53 ENSMUST00000054742.5
actin-binding Rho activating protein
chr2_-_173276526 0.53 ENSMUST00000036248.6
prostate transmembrane protein, androgen induced 1
chr3_-_66981279 0.53 ENSMUST00000162098.2
short stature homeobox 2
chr11_-_119086221 0.53 ENSMUST00000026665.7
chromobox 4
chr11_-_89302545 0.52 ENSMUST00000061728.3
noggin
chr1_-_36558214 0.52 ENSMUST00000154493.1
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr4_-_130574150 0.51 ENSMUST00000105993.3
Na+/K+ transporting ATPase interacting 1
chr19_-_47464406 0.51 ENSMUST00000111800.2
ENSMUST00000081619.2
SH3 and PX domains 2A
chr4_+_129513581 0.50 ENSMUST00000062356.6
MARCKS-like 1
chr15_-_85581809 0.50 ENSMUST00000023015.7
wingless-related MMTV integration site 7B
chr11_+_78343475 0.50 ENSMUST00000002127.7
ENSMUST00000108295.1
unc-119 homolog (C. elegans)
chr3_-_57847478 0.49 ENSMUST00000120289.1
ENSMUST00000066882.8
profilin 2
chr2_-_180954676 0.48 ENSMUST00000148905.1
ENSMUST00000103053.3
ENSMUST00000108873.2
Na+/K+ transporting ATPase interacting 4
chr17_-_46680870 0.48 ENSMUST00000165007.1
ENSMUST00000071841.5
kelch domain containing 3
chr2_+_156613664 0.48 ENSMUST00000169464.2
ENSMUST00000109567.3
discs, large homolog-associated protein 4 (Drosophila)
chr5_+_37028329 0.48 ENSMUST00000173836.1
janus kinase and microtubule interacting protein 1
chr1_+_75479529 0.48 ENSMUST00000113575.2
ENSMUST00000148980.1
ENSMUST00000050899.6
transmembrane protein 198
chr6_+_128362919 0.48 ENSMUST00000073316.6
forkhead box M1
chr7_+_29303938 0.47 ENSMUST00000108231.1
D4, zinc and double PHD fingers family 1
chr2_+_28192971 0.47 ENSMUST00000113920.1
olfactomedin 1
chr2_+_28205648 0.46 ENSMUST00000102879.3
ENSMUST00000028177.4
olfactomedin 1
chr17_+_68837062 0.46 ENSMUST00000178545.1
transmembrane protein 200C
chr12_+_81859964 0.46 ENSMUST00000021567.5
pecanex homolog (Drosophila)
chr6_-_72789240 0.46 ENSMUST00000069536.5
transcription factor 7 like 1 (T cell specific, HMG box)
chr4_+_133039482 0.46 ENSMUST00000105914.1
AT hook, DNA binding motif, containing 1
chr7_+_5051515 0.45 ENSMUST00000069324.5
zinc finger protein 580
chr18_-_13972617 0.45 ENSMUST00000025288.7
zinc finger protein 521
chr12_-_103242143 0.44 ENSMUST00000074416.3
proline rich membrane anchor 1
chr7_+_27258725 0.44 ENSMUST00000079258.6
numb-like
chr2_-_166996098 0.44 ENSMUST00000049412.5
staufen (RNA binding protein) homolog 1 (Drosophila)
chr7_+_67952817 0.44 ENSMUST00000005671.8
insulin-like growth factor I receptor
chr9_-_121277160 0.43 ENSMUST00000051479.6
ENSMUST00000171923.1
unc-51-like kinase 4
chr14_+_121035538 0.43 ENSMUST00000026635.7
FERM, RhoGEF (Arhgef) and pleckstrin domain protein 1 (chondrocyte-derived)
chr17_-_24073479 0.43 ENSMUST00000017090.5
potassium channel tetramerisation domain containing 5
chrX_+_151047170 0.43 ENSMUST00000026296.7
FYVE, RhoGEF and PH domain containing 1
chr17_+_34032348 0.43 ENSMUST00000173354.1
ENSMUST00000116612.2
retinoid X receptor beta
chr4_-_155734627 0.43 ENSMUST00000178987.1
RIKEN cDNA 1500002C15 gene
chr7_-_132813528 0.42 ENSMUST00000097999.2
family with sequence similarity 53, member B
chr12_-_79007276 0.42 ENSMUST00000056660.6
ENSMUST00000174721.1
transmembrane protein 229B
chr17_+_80944611 0.42 ENSMUST00000025092.4
transmembrane protein 178
chr15_+_88862178 0.42 ENSMUST00000042818.9
proviral integration site 3
chr7_-_102250086 0.41 ENSMUST00000106923.1
ENSMUST00000098230.4
ras homolog gene family, member G
chr16_+_17797282 0.41 ENSMUST00000012161.3
scavenger receptor class F, member 2
chr7_-_19665005 0.40 ENSMUST00000055242.9
cleft lip and palate associated transmembrane protein 1
chr17_+_8801742 0.39 ENSMUST00000089085.2
phosphodiesterase 10A
chr2_-_180954620 0.39 ENSMUST00000139929.1
Na+/K+ transporting ATPase interacting 4
chr2_+_167538192 0.39 ENSMUST00000052631.7
snail homolog 1 (Drosophila)
chr11_-_106159902 0.39 ENSMUST00000064545.4
LIM domain containing 2
chr19_+_4192129 0.38 ENSMUST00000046094.4
protein phosphatase 1, catalytic subunit, alpha isoform
chr1_+_89454769 0.38 ENSMUST00000027521.8
ENSMUST00000074945.5
ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr10_+_127739516 0.38 ENSMUST00000054287.7
zinc finger and BTB domain containing 39
chr15_-_97831460 0.37 ENSMUST00000079838.7
ENSMUST00000118294.1
histone deacetylase 7
chr7_-_30280335 0.37 ENSMUST00000108190.1
WD repeat domain 62
chr12_-_27342696 0.36 ENSMUST00000079063.5
SRY-box containing gene 11
chr12_-_102704896 0.36 ENSMUST00000178697.1
ENSMUST00000046518.5
inositol 1,3,4-triphosphate 5/6 kinase
chr18_+_84088077 0.36 ENSMUST00000060223.2
zinc binding alcohol dehydrogenase, domain containing 2
chr2_+_28193093 0.36 ENSMUST00000100244.3
olfactomedin 1
chr8_-_83699095 0.36 ENSMUST00000005616.8
protein kinase N1
chr6_-_4747157 0.36 ENSMUST00000090686.4
ENSMUST00000115579.1
ENSMUST00000115577.2
ENSMUST00000101677.3
ENSMUST00000004750.8
sarcoglycan, epsilon
chr17_-_47924635 0.35 ENSMUST00000113265.1
forkhead box P4
chr2_-_166996259 0.35 ENSMUST00000109238.2
ENSMUST00000109235.1
ENSMUST00000109236.2
staufen (RNA binding protein) homolog 1 (Drosophila)
chr2_-_33640480 0.35 ENSMUST00000176067.1
ENSMUST00000041730.4
LIM homeobox transcription factor 1 beta
chr12_-_108003594 0.35 ENSMUST00000066060.4
B cell leukemia/lymphoma 11B
chr3_-_90509450 0.35 ENSMUST00000107343.1
ENSMUST00000001043.7
ENSMUST00000107344.1
ENSMUST00000076639.4
ENSMUST00000107346.1
ENSMUST00000146740.1
ENSMUST00000107342.1
ENSMUST00000049937.6
chromatin target of PRMT1
chr15_+_101128574 0.35 ENSMUST00000117984.1
activin A receptor, type II-like 1
chr18_+_77773956 0.35 ENSMUST00000114748.1
ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1
chr8_-_87959560 0.34 ENSMUST00000109655.2
zinc finger protein 423
chr7_-_74013676 0.34 ENSMUST00000026896.4
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr2_-_166155272 0.34 ENSMUST00000088086.3
sulfatase 2
chr11_-_121354337 0.34 ENSMUST00000106110.3
ENSMUST00000136797.1
ENSMUST00000026173.6
WD repeat domain 45B
chr4_+_149586555 0.34 ENSMUST00000039144.6
calsyntenin 1
chr10_-_127666673 0.33 ENSMUST00000026469.2
Ngfi-A binding protein 2
chr6_-_53820764 0.33 ENSMUST00000127748.2
TLR4 interactor with leucine-rich repeats
chr11_+_69632927 0.33 ENSMUST00000018909.3
fragile X mental retardation, autosomal homolog 2
chr4_+_149586432 0.33 ENSMUST00000105691.1
calsyntenin 1
chr18_-_15063560 0.33 ENSMUST00000168989.1
potassium channel tetramerisation domain containing 1
chr11_+_69995874 0.33 ENSMUST00000101526.2
PHD finger protein 23
chr15_-_99457742 0.33 ENSMUST00000023747.7
NCK-associated protein 5-like
chr7_-_5038427 0.32 ENSMUST00000062428.4
zinc finger protein 784
chr2_-_166155624 0.32 ENSMUST00000109249.2
sulfatase 2
chr7_-_31150981 0.32 ENSMUST00000085636.6
ENSMUST00000001280.7
GRAM domain containing 1A
chr2_+_156008088 0.32 ENSMUST00000088650.4
ERGIC and golgi 3
chr2_+_156008045 0.32 ENSMUST00000006035.6
ERGIC and golgi 3
chr10_-_80918212 0.32 ENSMUST00000057623.7
ENSMUST00000179022.1
lamin B2
chr8_+_95081187 0.31 ENSMUST00000034239.7
katanin p80 (WD40-containing) subunit B 1
chr2_-_167349167 0.31 ENSMUST00000109221.2
UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 5
chr7_+_30280094 0.31 ENSMUST00000108187.1
ENSMUST00000014072.5
THAP domain containing 8
chr1_+_74601441 0.30 ENSMUST00000087183.4
ENSMUST00000148456.1
ENSMUST00000113694.1
serine/threonine kinase 36
chr11_+_69995777 0.30 ENSMUST00000018716.3
PHD finger protein 23
chr10_-_78352212 0.30 ENSMUST00000146899.1
1-acylglycerol-3-phosphate O-acyltransferase 3
chr17_-_44736648 0.30 ENSMUST00000113572.2
runt related transcription factor 2
chr4_+_42949814 0.30 ENSMUST00000037872.3
ENSMUST00000098112.2
DnaJ (Hsp40) homolog, subfamily B, member 5
chr2_-_152398046 0.30 ENSMUST00000063332.8
ENSMUST00000182625.1
SRY-box containing gene 12
chr15_-_79687776 0.30 ENSMUST00000023061.5
Josephin domain containing 1
chr12_-_108003414 0.29 ENSMUST00000109887.1
ENSMUST00000109891.2
B cell leukemia/lymphoma 11B
chr6_-_4747019 0.29 ENSMUST00000126151.1
ENSMUST00000133306.1
ENSMUST00000123907.1
sarcoglycan, epsilon
chr6_-_72788952 0.29 ENSMUST00000114053.2
transcription factor 7 like 1 (T cell specific, HMG box)
chr9_-_107635330 0.29 ENSMUST00000055704.6
guanine nucleotide binding protein (G protein), alpha inhibiting 2
chr9_-_119578981 0.28 ENSMUST00000117911.1
ENSMUST00000120420.1
sodium channel, voltage-gated, type V, alpha
chr19_+_56722372 0.28 ENSMUST00000038949.4
adrenergic receptor, beta 1
chr19_-_36057340 0.28 ENSMUST00000164639.1
ENSMUST00000166074.1
ENSMUST00000099505.3
5-hydroxytryptamine (serotonin) receptor 7
chr8_+_72723281 0.28 ENSMUST00000004494.8
ENSMUST00000109950.3
transcriptional regulator, SIN3B (yeast)
chr11_+_32642826 0.28 ENSMUST00000093205.6
ENSMUST00000076383.7
F-box and WD-40 domain protein 11
chr17_+_24895116 0.28 ENSMUST00000043907.7
mitochondrial ribosomal protein S34
chr7_-_120982260 0.28 ENSMUST00000033169.8
cerebellar degeneration-related 2
chr4_+_129984833 0.27 ENSMUST00000120204.1
brain-specific angiogenesis inhibitor 2
chr3_-_107333289 0.27 ENSMUST00000061772.9
RNA binding motif protein 15
chr16_+_20733104 0.27 ENSMUST00000115423.1
ENSMUST00000007171.6
chordin
chr10_-_78352053 0.27 ENSMUST00000105388.1
1-acylglycerol-3-phosphate O-acyltransferase 3
chr13_-_34345174 0.27 ENSMUST00000040336.5
solute carrier family 22, member 23
chr1_+_172148015 0.27 ENSMUST00000074144.5
DDB1 and CUL4 associated factor 8
chr14_+_122475397 0.26 ENSMUST00000075888.5
zinc finger protein of the cerebellum 2
chr11_-_50292302 0.26 ENSMUST00000059458.4
mastermind like 1 (Drosophila)
chr7_-_27674516 0.26 ENSMUST00000036453.7
ENSMUST00000108341.1
mitogen-activated protein kinase kinase kinase 10
chr12_+_3807017 0.26 ENSMUST00000020991.8
ENSMUST00000172509.1
DNA methyltransferase 3A
chr17_-_23740301 0.25 ENSMUST00000024702.3
progestin and adipoQ receptor family member IV
chr1_-_74601345 0.25 ENSMUST00000136078.1
ENSMUST00000132081.1
ENSMUST00000113721.1
ENSMUST00000027357.5
ring finger protein 25
chr14_-_105896819 0.25 ENSMUST00000022709.4
sprouty homolog 2 (Drosophila)
chr13_+_54949388 0.25 ENSMUST00000026994.7
ENSMUST00000109994.2
unc-5 homolog A (C. elegans)

Network of associatons between targets according to the STRING database.

First level regulatory network of Mbd2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:2000019 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748) positive regulation of dermatome development(GO:0061184) renal vesicle induction(GO:0072034) negative regulation of male gonad development(GO:2000019)
0.4 1.3 GO:0007521 muscle cell fate determination(GO:0007521)
0.4 1.9 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.3 0.9 GO:2000978 auditory receptor cell fate determination(GO:0042668) negative regulation of forebrain neuron differentiation(GO:2000978)
0.3 1.5 GO:0090005 negative regulation of Golgi to plasma membrane protein transport(GO:0042997) negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.2 0.7 GO:0046021 regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.2 0.9 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.2 0.9 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.2 0.6 GO:0097535 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.2 0.6 GO:0099526 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.2 0.6 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160)
0.2 2.0 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.2 1.2 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.2 0.5 GO:0060300 regulation of cytokine activity(GO:0060300)
0.2 0.7 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.2 1.0 GO:0070459 prolactin secretion(GO:0070459)
0.2 1.7 GO:1901250 regulation of lung goblet cell differentiation(GO:1901249) negative regulation of lung goblet cell differentiation(GO:1901250)
0.1 0.4 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.1 0.6 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.1 0.6 GO:0071692 protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694)
0.1 0.6 GO:1900619 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.1 0.6 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.1 0.5 GO:1902949 positive regulation of tau-protein kinase activity(GO:1902949)
0.1 0.5 GO:0072061 establishment or maintenance of polarity of embryonic epithelium(GO:0016332) renal outer medulla development(GO:0072054) inner medullary collecting duct development(GO:0072061)
0.1 0.5 GO:2001287 negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.1 0.5 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.1 1.3 GO:0023041 neuronal signal transduction(GO:0023041)
0.1 0.4 GO:1903943 estrous cycle(GO:0044849) regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1 0.5 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 0.4 GO:0060709 glycogen cell differentiation involved in embryonic placenta development(GO:0060709)
0.1 1.6 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 0.6 GO:0009405 pathogenesis(GO:0009405)
0.1 0.4 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1 0.3 GO:0086047 membrane depolarization during Purkinje myocyte cell action potential(GO:0086047)
0.1 0.3 GO:1900135 positive regulation of renin secretion into blood stream(GO:1900135)
0.1 0.3 GO:0051385 response to mineralocorticoid(GO:0051385)
0.1 0.6 GO:0051611 serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611)
0.1 0.9 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.1 0.7 GO:0051013 microtubule severing(GO:0051013)
0.1 0.6 GO:0071896 protein localization to adherens junction(GO:0071896)
0.1 0.3 GO:0003162 atrioventricular node development(GO:0003162)
0.1 0.5 GO:0072675 osteoclast fusion(GO:0072675)
0.1 1.5 GO:0033574 response to testosterone(GO:0033574)
0.1 0.3 GO:1900175 regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145) regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900175) positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.1 1.0 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.1 0.7 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.1 0.3 GO:0033128 negative regulation of histone phosphorylation(GO:0033128)
0.1 0.3 GO:0001887 selenium compound metabolic process(GO:0001887) selenocysteine metabolic process(GO:0016259)
0.1 0.2 GO:0001192 maintenance of transcriptional fidelity during DNA-templated transcription elongation(GO:0001192) maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter(GO:0001193)
0.1 0.5 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 0.1 GO:2000977 regulation of forebrain neuron differentiation(GO:2000977)
0.1 0.2 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.1 0.2 GO:0071930 positive regulation of DNA endoreduplication(GO:0032877) negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.1 0.1 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.1 0.4 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.1 0.2 GO:0036509 trimming of terminal mannose on B branch(GO:0036509)
0.1 0.2 GO:0070904 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.1 2.3 GO:0055012 ventricular cardiac muscle cell differentiation(GO:0055012)
0.1 0.2 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
0.1 0.5 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.1 0.5 GO:0001922 B-1 B cell homeostasis(GO:0001922)
0.1 1.2 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.1 0.2 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.1 0.2 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.1 1.0 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.1 0.3 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.1 0.2 GO:0043973 histone H3-K4 acetylation(GO:0043973)
0.1 0.1 GO:0071317 cellular response to isoquinoline alkaloid(GO:0071317)
0.0 0.6 GO:0051014 actin filament severing(GO:0051014)
0.0 0.1 GO:0010360 negative regulation of anion channel activity(GO:0010360)
0.0 0.1 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.0 0.1 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.0 0.1 GO:0001743 optic placode formation(GO:0001743)
0.0 1.0 GO:0044804 nucleophagy(GO:0044804)
0.0 1.2 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.3 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0 0.1 GO:0048007 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0 0.8 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.0 0.5 GO:2000781 positive regulation of double-strand break repair(GO:2000781)
0.0 0.1 GO:1902162 regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162)
0.0 0.5 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.4 GO:0090500 endocardial cushion to mesenchymal transition(GO:0090500)
0.0 1.0 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.0 0.4 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.0 0.1 GO:0019401 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401)
0.0 0.6 GO:0048505 regulation of timing of cell differentiation(GO:0048505)
0.0 0.2 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.1 GO:0021586 pons maturation(GO:0021586)
0.0 0.2 GO:0051365 cellular response to potassium ion starvation(GO:0051365)
0.0 1.3 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.0 0.4 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.2 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.0 0.2 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.2 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.1 GO:0060854 patterning of lymph vessels(GO:0060854)
0.0 0.4 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.5 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.1 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.0 0.4 GO:0042048 olfactory behavior(GO:0042048)
0.0 0.6 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.3 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.4 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.2 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.0 0.2 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
0.0 0.6 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.1 GO:2001025 positive regulation of response to drug(GO:2001025)
0.0 0.6 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.7 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.2 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.2 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.0 0.3 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 0.4 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.7 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.0 0.2 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.0 0.4 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.0 0.1 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.1 GO:0060596 mammary placode formation(GO:0060596)
0.0 0.5 GO:0021535 cell migration in hindbrain(GO:0021535)
0.0 0.1 GO:0010626 regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626)
0.0 0.4 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.0 1.8 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.0 0.2 GO:0036010 protein localization to endosome(GO:0036010)
0.0 1.0 GO:0010830 regulation of myotube differentiation(GO:0010830)
0.0 0.2 GO:0072498 embryonic skeletal joint development(GO:0072498)
0.0 0.1 GO:0021592 fourth ventricle development(GO:0021592) initiation of neural tube closure(GO:0021993)
0.0 0.1 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.0 0.4 GO:1900027 regulation of ruffle assembly(GO:1900027)
0.0 0.1 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.0 0.4 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.0 0.4 GO:0033081 regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398)
0.0 0.1 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 0.5 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.4 GO:0043496 regulation of protein homodimerization activity(GO:0043496)
0.0 0.3 GO:0043536 positive regulation of blood vessel endothelial cell migration(GO:0043536)
0.0 0.5 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.1 GO:0032534 regulation of microvillus assembly(GO:0032534) intestinal epithelial cell development(GO:0060576)
0.0 0.3 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.4 GO:0034142 toll-like receptor 4 signaling pathway(GO:0034142)
0.0 0.6 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.2 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.0 0.2 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.1 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.0 0.0 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.0 0.4 GO:0035411 catenin import into nucleus(GO:0035411)
0.0 0.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.4 GO:0010595 positive regulation of endothelial cell migration(GO:0010595)
0.0 0.1 GO:0015886 heme transport(GO:0015886)
0.0 0.0 GO:0086045 membrane depolarization during AV node cell action potential(GO:0086045) membrane depolarization during SA node cell action potential(GO:0086046)
0.0 0.2 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.2 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.6 GO:0045453 bone resorption(GO:0045453)
0.0 0.2 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.8 GO:0000813 ESCRT I complex(GO:0000813)
0.2 0.6 GO:1990257 piccolo-bassoon transport vesicle(GO:1990257)
0.1 0.6 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 1.2 GO:0000124 SAGA complex(GO:0000124)
0.1 0.6 GO:0070578 RISC-loading complex(GO:0070578)
0.1 0.4 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 1.3 GO:0071565 nBAF complex(GO:0071565)
0.0 0.4 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.3 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.1 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.3 GO:0005638 lamin filament(GO:0005638)
0.0 1.0 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.3 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 0.6 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.4 GO:0000805 X chromosome(GO:0000805)
0.0 2.1 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.1 GO:0098830 presynaptic endosome(GO:0098830)
0.0 1.9 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.1 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0 0.6 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 1.0 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.6 GO:0031105 septin complex(GO:0031105)
0.0 0.5 GO:0035102 PRC1 complex(GO:0035102)
0.0 1.0 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.0 GO:0000125 PCAF complex(GO:0000125)
0.0 1.2 GO:0031201 SNARE complex(GO:0031201)
0.0 1.0 GO:0008305 integrin complex(GO:0008305)
0.0 0.6 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.7 GO:0051233 spindle midzone(GO:0051233)
0.0 0.1 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.9 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.1 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.2 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.4 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.1 GO:1990032 climbing fiber(GO:0044301) parallel fiber(GO:1990032)
0.0 0.1 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 1.5 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.1 GO:0071144 activin responsive factor complex(GO:0032444) SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.7 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.1 GO:0097059 CRLF-CLCF1 complex(GO:0097058) CNTFR-CLCF1 complex(GO:0097059)
0.0 0.1 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 1.5 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.5 GO:0002102 podosome(GO:0002102)
0.0 0.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.8 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.3 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.2 1.0 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.2 0.6 GO:0004104 cholinesterase activity(GO:0004104)
0.1 0.6 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1 0.7 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.5 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
0.1 0.4 GO:0051765 inositol tetrakisphosphate kinase activity(GO:0051765)
0.1 0.4 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.1 0.4 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.1 2.1 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.5 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.1 1.6 GO:0022841 potassium ion leak channel activity(GO:0022841) S100 protein binding(GO:0044548)
0.1 0.2 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 0.3 GO:0070279 vitamin B6 binding(GO:0070279)
0.1 1.5 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 0.3 GO:0031694 beta-adrenergic receptor activity(GO:0004939) alpha-2A adrenergic receptor binding(GO:0031694)
0.1 0.2 GO:0015229 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.1 0.3 GO:0043532 angiostatin binding(GO:0043532)
0.1 0.3 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 1.9 GO:0015215 nucleotide transmembrane transporter activity(GO:0015215)
0.1 0.6 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 0.5 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 0.3 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.4 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.1 0.2 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.1 1.1 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.4 GO:0043559 insulin binding(GO:0043559)
0.0 0.3 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.2 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.2 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.2 GO:0070052 collagen V binding(GO:0070052)
0.0 0.2 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.3 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.2 GO:0051766 inositol trisphosphate kinase activity(GO:0051766)
0.0 0.1 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 1.3 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.3 GO:0045545 syndecan binding(GO:0045545)
0.0 0.0 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.8 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.1 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.0 1.0 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.2 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.5 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.7 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 1.7 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.4 GO:0043495 protein anchor(GO:0043495)
0.0 1.1 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 1.1 GO:0005109 frizzled binding(GO:0005109)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.3 GO:0051378 serotonin binding(GO:0051378)
0.0 0.6 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.1 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.0 0.2 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 0.5 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.4 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 1.3 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.1 GO:0005113 patched binding(GO:0005113)
0.0 4.5 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.4 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.9 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.0 1.2 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.4 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 1.2 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 1.1 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.5 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.6 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.1 GO:0015198 oligopeptide transporter activity(GO:0015198)
0.0 0.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.7 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.4 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.3 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.1 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.3 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.4 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.7 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.0 GO:0004103 choline kinase activity(GO:0004103)
0.0 0.0 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0 0.8 GO:0019003 GDP binding(GO:0019003)
0.0 0.7 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.5 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.0 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.0 0.4 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 1.2 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 0.5 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.1 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.9 GO:0008013 beta-catenin binding(GO:0008013)
0.0 3.9 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 2.3 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.2 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.4 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.8 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 2.6 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 3.7 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.4 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 1.2 PID BMP PATHWAY BMP receptor signaling
0.0 0.5 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.8 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.2 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.7 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.4 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.4 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.5 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.8 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.1 1.6 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 1.3 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.4 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.9 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.4 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.7 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 1.5 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.3 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 2.9 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 2.3 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.6 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 1.1 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.3 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.5 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.3 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.6 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.0 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 0.7 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.3 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.4 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 1.0 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.2 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.2 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.1 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.4 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.3 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.3 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors