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GSE58827: Dynamics of the Mouse Liver

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Results for Msx1_Lhx9_Barx1_Rax_Dlx6

Z-value: 0.58

Motif logo

Transcription factors associated with Msx1_Lhx9_Barx1_Rax_Dlx6

Gene Symbol Gene ID Gene Info
ENSMUSG00000048450.10 msh homeobox 1
ENSMUSG00000019230.8 LIM homeobox protein 9
ENSMUSG00000021381.4 BarH-like homeobox 1
ENSMUSG00000024518.3 retina and anterior neural fold homeobox
ENSMUSG00000029754.7 distal-less homeobox 6

Activity-expression correlation:

Activity profile of Msx1_Lhx9_Barx1_Rax_Dlx6 motif

Sorted Z-values of Msx1_Lhx9_Barx1_Rax_Dlx6 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_99322943 4.50 ENSMUST00000038004.2
keratin 25
chr4_+_34893772 3.85 ENSMUST00000029975.3
ENSMUST00000135871.1
ENSMUST00000108130.1
glycoprotein hormones, alpha subunit
chr5_-_134747241 2.78 ENSMUST00000015138.9
elastin
chr7_+_126950518 2.30 ENSMUST00000106335.1
ENSMUST00000146017.1
seizure related 6 homolog like 2
chr2_-_168767029 2.24 ENSMUST00000075044.3
sal-like 4 (Drosophila)
chr7_+_126950687 2.21 ENSMUST00000106333.1
seizure related 6 homolog like 2
chr14_+_27000362 2.01 ENSMUST00000035433.8
homeobox gene expressed in ES cells
chr1_-_79440039 2.00 ENSMUST00000049972.4
secretogranin II
chr7_+_126950837 1.86 ENSMUST00000106332.1
seizure related 6 homolog like 2
chr2_-_72986716 1.56 ENSMUST00000112062.1
predicted gene 11084
chr3_-_116253467 1.52 ENSMUST00000090473.5
G-protein coupled receptor 88
chr6_-_116716888 1.46 ENSMUST00000056623.6
transmembrane protein 72
chr9_+_43310763 1.45 ENSMUST00000034511.5
tripartite motif-containing 29
chr12_-_83487708 1.34 ENSMUST00000177959.1
ENSMUST00000178756.1
D4, zinc and double PHD fingers, family 3
chr12_+_109545390 1.32 ENSMUST00000146701.1
maternally expressed 3
chr2_+_69219971 1.27 ENSMUST00000005364.5
ENSMUST00000112317.2
glucose-6-phosphatase, catalytic, 2
chr2_+_9882622 1.16 ENSMUST00000114919.1
RIKEN cDNA 4930412O13 gene
chr16_-_42340595 1.12 ENSMUST00000102817.4
growth associated protein 43
chr11_+_67200052 1.10 ENSMUST00000124516.1
ENSMUST00000018637.8
myosin, heavy polypeptide 1, skeletal muscle, adult
chr2_-_168767136 1.10 ENSMUST00000029061.5
ENSMUST00000103074.1
sal-like 4 (Drosophila)
chr10_+_115569986 1.08 ENSMUST00000173620.1
RIKEN cDNA A930009A15 gene
chr11_+_102604370 1.07 ENSMUST00000057893.5
frizzled homolog 2 (Drosophila)
chr6_-_136781718 1.05 ENSMUST00000078095.6
ENSMUST00000032338.7
guanylate cyclase 2c
chr2_+_74697663 1.05 ENSMUST00000059272.8
homeobox D9
chr15_-_79285502 0.99 ENSMUST00000165408.1
BAI1-associated protein 2-like 2
chr9_+_43829963 0.92 ENSMUST00000180221.1
predicted gene 3898
chr16_-_63864114 0.90 ENSMUST00000064405.6
Eph receptor A3
chr2_-_116067391 0.84 ENSMUST00000140185.1
RIKEN cDNA 2700033N17 gene
chr13_-_78196373 0.84 ENSMUST00000125176.2
nuclear receptor subfamily 2, group F, member 1
chr2_+_127909058 0.83 ENSMUST00000110344.1
acyl-Coenzyme A oxidase-like
chr15_-_79285470 0.79 ENSMUST00000170955.1
BAI1-associated protein 2-like 2
chr2_+_25372315 0.75 ENSMUST00000028329.6
ENSMUST00000114293.2
ENSMUST00000100323.2
suppressor APC domain containing 2
chr7_-_66427469 0.73 ENSMUST00000015278.7
aldehyde dehydrogenase family 1, subfamily A3
chr3_-_49757257 0.72 ENSMUST00000035931.7
protocadherin 18
chr13_+_55399648 0.70 ENSMUST00000057167.7
solute carrier family 34 (sodium phosphate), member 1
chr18_+_23415400 0.70 ENSMUST00000115832.2
ENSMUST00000047954.7
dystrobrevin alpha
chr11_-_87359011 0.69 ENSMUST00000055438.4
protein phosphatase 1E (PP2C domain containing)
chr14_-_110755100 0.68 ENSMUST00000078386.2
SLIT and NTRK-like family, member 6
chr6_+_125552948 0.67 ENSMUST00000112254.1
ENSMUST00000112253.1
ENSMUST00000001995.7
Von Willebrand factor homolog
chr19_-_7966000 0.67 ENSMUST00000182102.1
ENSMUST00000075619.4
solute carrier family 22, member 27
chr5_-_53707532 0.65 ENSMUST00000031093.3
cholecystokinin A receptor
chr17_-_35697971 0.65 ENSMUST00000146472.1
discoidin domain receptor family, member 1
chr5_+_34999111 0.64 ENSMUST00000114283.1
regulator of G-protein signaling 12
chr19_-_55241236 0.62 ENSMUST00000069183.6
guanylate cyclase 2g
chr5_+_34999046 0.62 ENSMUST00000114281.1
regulator of G-protein signaling 12
chr15_-_13173607 0.60 ENSMUST00000036439.4
cadherin 6
chr3_+_68572245 0.59 ENSMUST00000170788.2
schwannomin interacting protein 1
chr17_-_31198958 0.59 ENSMUST00000114549.2
transmembrane protease, serine 3
chr15_-_34356421 0.57 ENSMUST00000179647.1
RIKEN cDNA 9430069I07 gene
chr17_+_49615104 0.56 ENSMUST00000162854.1
kinesin family member 6
chrX_-_139871637 0.54 ENSMUST00000033811.7
ENSMUST00000087401.5
microrchidia 4
chr11_-_99244058 0.53 ENSMUST00000103132.3
ENSMUST00000038214.6
keratin 222
chr11_+_67798269 0.52 ENSMUST00000168612.1
ENSMUST00000040574.4
dehydrogenase/reductase (SDR family) member 7C
chr9_-_40346290 0.50 ENSMUST00000121357.1
GRAM domain containing 1B
chrX_-_74246534 0.49 ENSMUST00000101454.2
ENSMUST00000033699.6
filamin, alpha
chr1_-_4360256 0.46 ENSMUST00000027032.4
retinitis pigmentosa 1 (human)
chr5_+_34999070 0.45 ENSMUST00000114280.1
regulator of G-protein signaling 12
chr17_+_27556641 0.45 ENSMUST00000119486.1
ENSMUST00000118599.1
high mobility group AT-hook 1
chr9_+_45370185 0.45 ENSMUST00000085939.6
FXYD domain-containing ion transport regulator 6
chr7_-_45830776 0.45 ENSMUST00000107723.2
ENSMUST00000131384.1
glutamate-rich WD repeat containing 1
chr2_+_38341068 0.44 ENSMUST00000133661.1
LIM homeobox protein 2
chr17_+_35533194 0.44 ENSMUST00000025273.8
psoriasis susceptibility 1 candidate 2 (human)
chr17_+_27556668 0.44 ENSMUST00000117254.1
ENSMUST00000118570.1
high mobility group AT-hook 1
chr9_+_119063429 0.44 ENSMUST00000141185.1
ENSMUST00000126251.1
ENSMUST00000136561.1
villin-like
chr2_+_152754156 0.43 ENSMUST00000010020.5
cytochrome c oxidase subunit IV isoform 2
chr17_+_27556613 0.42 ENSMUST00000117600.1
ENSMUST00000114888.3
high mobility group AT-hook 1
chr9_+_106368594 0.42 ENSMUST00000172306.2
dual specificity phosphatase 7
chr9_+_38877126 0.42 ENSMUST00000078289.2
olfactory receptor 926
chr11_-_98053415 0.41 ENSMUST00000017544.2
SH3 and cysteine rich domain 2
chr3_+_159839729 0.40 ENSMUST00000068952.5
wntless homolog (Drosophila)
chr10_-_80421847 0.39 ENSMUST00000156244.1
transcription factor 3
chr10_-_53647080 0.38 ENSMUST00000169866.1
family with sequence similarity 184, member A
chr13_-_113663670 0.37 ENSMUST00000054650.4
heat shock protein 3
chr4_+_5724304 0.37 ENSMUST00000108380.1
family with sequence similarity 110, member B
chr6_-_30958990 0.36 ENSMUST00000101589.3
Kruppel-like factor 14
chr6_+_123262107 0.36 ENSMUST00000032240.2
C-type lectin domain family 4, member d
chr18_-_37969742 0.34 ENSMUST00000166148.1
ENSMUST00000163131.1
ENSMUST00000043437.7
FCH and double SH3 domains 1
chr16_+_45093611 0.34 ENSMUST00000099498.2
coiled-coil domain containing 80
chr3_-_55055038 0.32 ENSMUST00000029368.2
cyclin A1
chr17_-_49564262 0.31 ENSMUST00000057610.6
dishevelled associated activator of morphogenesis 2
chr16_-_74411292 0.31 ENSMUST00000117200.1
roundabout homolog 2 (Drosophila)
chr12_+_52699297 0.31 ENSMUST00000095737.3
A kinase (PRKA) anchor protein 6
chr8_+_121116163 0.30 ENSMUST00000054691.6
forkhead box C2
chr8_+_4238733 0.30 ENSMUST00000110998.2
ENSMUST00000062686.4
mitogen-activated protein kinase kinase 7
chr2_-_45117349 0.30 ENSMUST00000176438.2
zinc finger E-box binding homeobox 2
chr17_+_12119274 0.30 ENSMUST00000024594.2
1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta)
chrX_+_56454871 0.30 ENSMUST00000039374.2
ENSMUST00000101553.2
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
chr8_-_79248537 0.28 ENSMUST00000034109.4
RIKEN cDNA 1700011L22 gene
chr9_+_96258697 0.28 ENSMUST00000179416.1
transcription factor Dp 2
chr17_-_29888570 0.27 ENSMUST00000171691.1
MAM domain containing glycosylphosphatidylinositol anchor 1
chr11_+_67200137 0.27 ENSMUST00000129018.1
myosin, heavy polypeptide 1, skeletal muscle, adult
chrX_+_133850980 0.26 ENSMUST00000033602.8
tenomodulin
chr2_+_27165233 0.26 ENSMUST00000000910.6
dopamine beta hydroxylase
chr7_+_43781054 0.26 ENSMUST00000014058.9
kallikrein related-peptidase 10
chr17_+_46161021 0.26 ENSMUST00000024748.7
ENSMUST00000172170.1
GTP binding protein 2
chr1_-_52190901 0.26 ENSMUST00000156887.1
ENSMUST00000129107.1
glutaminase
chr11_-_119547744 0.26 ENSMUST00000026670.4
neuronal pentraxin 1
chr7_+_30763750 0.25 ENSMUST00000165887.1
ENSMUST00000085691.4
ENSMUST00000085688.4
ENSMUST00000054427.6
dermokine
chr8_+_4238815 0.25 ENSMUST00000003027.7
ENSMUST00000110999.1
mitogen-activated protein kinase kinase 7
chr6_-_52226165 0.25 ENSMUST00000114425.2
homeobox A9
chr13_-_53473074 0.24 ENSMUST00000021922.8
msh homeobox 2
chr2_+_130012336 0.24 ENSMUST00000110299.2
transglutaminase 3, E polypeptide
chr15_-_66812593 0.23 ENSMUST00000100572.3
src-like adaptor
chr6_-_128275577 0.23 ENSMUST00000130454.1
TEA domain family member 4
chr15_+_101473472 0.23 ENSMUST00000088049.3
keratin 86
chr12_-_111813834 0.22 ENSMUST00000021715.5
X-ray repair complementing defective repair in Chinese hamster cells 3
chr5_+_27261916 0.22 ENSMUST00000101471.3
dipeptidylpeptidase 6
chr2_+_52038005 0.22 ENSMUST00000065927.5
tumor necrosis factor alpha induced protein 6
chr19_+_24673998 0.22 ENSMUST00000057243.4
transmembrane protein 252
chr5_-_5266038 0.21 ENSMUST00000115451.1
ENSMUST00000115452.1
ENSMUST00000131392.1
cyclin-dependent kinase 14
chr2_+_3114220 0.21 ENSMUST00000072955.5
family with sequence similarity 171, member A1
chrX_+_159303266 0.21 ENSMUST00000112491.1
ribosomal protein S6 kinase polypeptide 3
chr18_-_24603464 0.20 ENSMUST00000154205.1
solute carrier family 39 (metal ion transporter), member 6
chr12_+_38781093 0.20 ENSMUST00000161513.1
ets variant gene 1
chr12_-_104473236 0.20 ENSMUST00000021513.4
goosecoid homeobox
chr2_+_106693185 0.20 ENSMUST00000111063.1
metallophosphoesterase domain containing 2
chr15_+_102966794 0.19 ENSMUST00000001699.7
homeobox C10
chr13_+_118714678 0.19 ENSMUST00000022246.8
fibroblast growth factor 10
chr13_-_73678005 0.19 ENSMUST00000022105.7
ENSMUST00000109680.2
ENSMUST00000109679.2
solute carrier family 6 (neurotransmitter transporter), member 18
chr10_+_88146992 0.19 ENSMUST00000052355.7
nucleoporin 37
chr17_+_75005523 0.19 ENSMUST00000001927.5
latent transforming growth factor beta binding protein 1
chr4_-_129558355 0.18 ENSMUST00000167288.1
ENSMUST00000134336.1
lymphocyte protein tyrosine kinase
chr4_-_129558387 0.18 ENSMUST00000067240.4
lymphocyte protein tyrosine kinase
chr6_+_37870786 0.17 ENSMUST00000120428.1
ENSMUST00000031859.7
tripartite motif-containing 24
chr18_-_24603791 0.17 ENSMUST00000070726.3
solute carrier family 39 (metal ion transporter), member 6
chr1_-_172027269 0.17 ENSMUST00000027837.6
ENSMUST00000111264.1
vang-like 2 (van gogh, Drosophila)
chr15_+_79690869 0.16 ENSMUST00000046463.8
GTP binding protein 1
chr1_-_172027251 0.16 ENSMUST00000138714.1
vang-like 2 (van gogh, Drosophila)
chr6_-_102464667 0.16 ENSMUST00000032159.6
contactin 3
chr14_-_108914237 0.16 ENSMUST00000100322.2
SLIT and NTRK-like family, member 1
chr6_+_6248659 0.16 ENSMUST00000181633.1
ENSMUST00000176283.1
ENSMUST00000175814.1
ENSMUST00000181192.1
predicted gene 20619
chr10_+_88885992 0.16 ENSMUST00000020255.6
solute carrier family 5 (iodide transporter), member 8
chr6_-_147264124 0.16 ENSMUST00000052296.6
parathyroid hormone-like peptide
chrX_+_166344692 0.15 ENSMUST00000112223.1
ENSMUST00000112224.1
ENSMUST00000112229.2
ENSMUST00000112228.1
ENSMUST00000112227.2
ENSMUST00000112226.2
glycoprotein m6b
chr1_+_172555932 0.15 ENSMUST00000061835.3
V-set and immunoglobulin domain containing 8
chr5_-_122989086 0.15 ENSMUST00000046073.9
lysine (K)-specific demethylase 2B
chr3_+_55782500 0.14 ENSMUST00000075422.4
mab-21-like 1 (C. elegans)
chr3_+_61364507 0.14 ENSMUST00000049064.2
RAP2B, member of RAS oncogene family
chr14_-_37098211 0.14 ENSMUST00000022337.9
cadherin-related family member 1
chr5_-_122989260 0.13 ENSMUST00000118027.1
lysine (K)-specific demethylase 2B
chr9_-_103222063 0.13 ENSMUST00000170904.1
transferrin
chr1_+_110099295 0.13 ENSMUST00000134301.1
cadherin 7, type 2
chr8_+_83666827 0.13 ENSMUST00000019608.5
prostaglandin E receptor 1 (subtype EP1)
chr2_+_86007778 0.13 ENSMUST00000062166.1
olfactory receptor 1032
chr10_+_102159000 0.12 ENSMUST00000020039.6
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr8_-_62123106 0.12 ENSMUST00000034052.6
ENSMUST00000034054.7
annexin A10
chr1_-_152625212 0.12 ENSMUST00000027760.7
ral guanine nucleotide dissociation stimulator,-like 1
chr17_+_34039437 0.12 ENSMUST00000131134.1
ENSMUST00000087497.4
ENSMUST00000114255.1
ENSMUST00000114252.1
collagen, type XI, alpha 2
chr11_+_52098681 0.12 ENSMUST00000020608.2
protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform
chr8_-_87959560 0.12 ENSMUST00000109655.2
zinc finger protein 423
chr13_+_111255010 0.12 ENSMUST00000054716.3
actin, beta-like 2
chr8_-_120228221 0.12 ENSMUST00000183235.1
RIKEN cDNA A330074K22 gene
chr5_+_138187485 0.12 ENSMUST00000110934.2
canopy 4 homolog (zebrafish)
chr10_+_99263224 0.11 ENSMUST00000020118.4
dual specificity phosphatase 6
chr2_+_71389239 0.11 ENSMUST00000028408.2
histone aminotransferase 1
chr9_-_79977782 0.11 ENSMUST00000093811.4
filamin A interacting protein 1
chr9_+_102506072 0.11 ENSMUST00000039390.4
kyphoscoliosis peptidase
chr10_+_73821857 0.11 ENSMUST00000177128.1
ENSMUST00000064562.7
ENSMUST00000129404.2
ENSMUST00000105426.3
ENSMUST00000131321.2
ENSMUST00000126920.2
ENSMUST00000147189.2
ENSMUST00000105424.3
ENSMUST00000092420.6
ENSMUST00000105429.3
ENSMUST00000131724.2
ENSMUST00000152655.2
ENSMUST00000151116.2
ENSMUST00000155701.2
ENSMUST00000152819.2
ENSMUST00000125517.2
ENSMUST00000124046.1
ENSMUST00000149977.2
ENSMUST00000146682.1
ENSMUST00000177107.1
protocadherin 15
chr4_-_58206596 0.11 ENSMUST00000042850.8
sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
chr5_-_122988533 0.11 ENSMUST00000086200.4
ENSMUST00000156474.1
lysine (K)-specific demethylase 2B
chr11_-_97700327 0.11 ENSMUST00000018681.7
polycomb group ring finger 2
chr9_+_17030045 0.11 ENSMUST00000164523.2
predicted gene 5611
chr17_+_17402672 0.11 ENSMUST00000115576.2
limb expression 1 homolog (chicken)
chr4_-_58499398 0.10 ENSMUST00000107570.1
lysophosphatidic acid receptor 1
chr13_-_106847267 0.10 ENSMUST00000057427.4
leucine rich repeat containing 70
chr13_+_55445301 0.10 ENSMUST00000001115.8
ENSMUST00000099482.3
G protein-coupled receptor kinase 6
chr2_+_78051155 0.10 ENSMUST00000145972.1
RIKEN cDNA 4930440I19 gene
chr2_+_78051220 0.10 ENSMUST00000144728.1
RIKEN cDNA 4930440I19 gene
chr16_-_95586585 0.10 ENSMUST00000077773.6
avian erythroblastosis virus E-26 (v-ets) oncogene related
chr2_-_72813665 0.09 ENSMUST00000136807.1
ENSMUST00000148327.1
RIKEN cDNA 6430710C18 gene
chr7_-_44986313 0.09 ENSMUST00000045325.6
ENSMUST00000085387.4
ENSMUST00000107840.1
ENSMUST00000107843.3
ENSMUST00000107842.3
protein arginine N-methyltransferase 1
chr6_+_15196949 0.09 ENSMUST00000151301.1
ENSMUST00000131414.1
ENSMUST00000140557.1
ENSMUST00000115469.1
forkhead box P2
chr5_-_137531952 0.09 ENSMUST00000140139.1
guanine nucleotide binding protein (G protein), beta 2
chr15_+_21111452 0.09 ENSMUST00000075132.6
cadherin 12
chr19_-_5560570 0.08 ENSMUST00000025861.1
OVO homolog-like 1 (Drosophila)
chr18_-_61707583 0.08 ENSMUST00000025472.1
prenylcysteine oxidase 1 like
chr7_+_101896817 0.08 ENSMUST00000143835.1
anaphase prompoting complex C subunit 15
chr6_+_87428986 0.08 ENSMUST00000032125.5
bone morphogenetic protein 10
chr10_+_102158858 0.08 ENSMUST00000138522.1
ENSMUST00000163753.1
ENSMUST00000138016.1
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr7_+_25681158 0.08 ENSMUST00000108403.3
B9 protein domain 2
chr18_+_44104407 0.08 ENSMUST00000081271.5
serine peptidase inhibitor, Kazal type 11
chr1_-_158356258 0.08 ENSMUST00000004133.8
bone morphogenic protein/retinoic acid inducible neural-specific 2
chr16_-_97170707 0.07 ENSMUST00000056102.7
Down syndrome cell adhesion molecule
chr7_-_102210120 0.07 ENSMUST00000070165.5
nucleoporin 98
chr1_-_126738167 0.07 ENSMUST00000160693.1
NCK-associated protein 5
chr4_+_21848039 0.07 ENSMUST00000098238.2
ENSMUST00000108229.1
serine/arginine-rich splicing factor 18
chr2_+_153938218 0.07 ENSMUST00000109757.1
BPI fold containing family B, member 4
chr18_+_37819543 0.07 ENSMUST00000055935.5
protocadherin gamma subfamily A, 9
chr7_-_81493725 0.06 ENSMUST00000119121.1
adaptor-related protein complex 3, beta 2 subunit
chr1_+_132298606 0.06 ENSMUST00000046071.4
kelch domain containing 8A
chr16_-_29544852 0.06 ENSMUST00000039090.8
ATPase type 13A4
chr3_-_59220150 0.06 ENSMUST00000170388.1
purinergic receptor P2Y, G-protein coupled 12
chr1_+_137928100 0.06 ENSMUST00000054333.2
RIKEN cDNA A130050O07 gene
chr4_+_19280850 0.06 ENSMUST00000102999.1
cyclic nucleotide gated channel beta 3
chr15_+_92597104 0.06 ENSMUST00000035399.8
PDZ domain containing RING finger 4
chr12_+_72441933 0.06 ENSMUST00000161284.1
leucine rich repeat containing 9
chr7_-_116198487 0.05 ENSMUST00000181981.1
pleckstrin homology domain containing, family A member 7
chr13_+_42680565 0.05 ENSMUST00000128646.1
phosphatase and actin regulator 1
chr8_+_54954728 0.05 ENSMUST00000033915.7
glycoprotein m6a
chr4_+_19818722 0.05 ENSMUST00000035890.7
solute carrier family 7, (cationic amino acid transporter, y+ system) member 13

Network of associatons between targets according to the STRING database.

First level regulatory network of Msx1_Lhx9_Barx1_Rax_Dlx6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.5 GO:0061743 motor learning(GO:0061743)
0.4 1.1 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.3 1.7 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.3 0.9 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.3 3.7 GO:0046884 follicle-stimulating hormone secretion(GO:0046884)
0.2 0.7 GO:0060166 olfactory pit development(GO:0060166)
0.2 0.7 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
0.2 6.4 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.2 2.2 GO:0030916 otic vesicle formation(GO:0030916)
0.2 0.7 GO:0090274 positive regulation of somatostatin secretion(GO:0090274)
0.2 3.3 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.2 0.7 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.2 0.5 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.2 4.5 GO:0045109 intermediate filament organization(GO:0045109)
0.2 2.0 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.2 1.4 GO:0016198 axon choice point recognition(GO:0016198)
0.1 0.4 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.1 0.2 GO:0051795 positive regulation of catagen(GO:0051795)
0.1 0.7 GO:0060005 vestibular reflex(GO:0060005)
0.1 0.3 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490) non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.1 0.3 GO:1902256 apoptotic process involved in outflow tract morphogenesis(GO:0003275) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.1 1.3 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 0.3 GO:0046333 octopamine biosynthetic process(GO:0006589) octopamine metabolic process(GO:0046333)
0.1 0.2 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.1 0.4 GO:0021993 initiation of neural tube closure(GO:0021993)
0.1 1.8 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 0.4 GO:0038094 Fc-gamma receptor signaling pathway(GO:0038094)
0.1 0.3 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.1 0.3 GO:1903575 cornified envelope assembly(GO:1903575)
0.1 0.3 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.1 0.7 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 0.3 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.1 1.3 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.1 0.3 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 0.4 GO:0002326 B cell lineage commitment(GO:0002326)
0.0 0.7 GO:0015747 urate transport(GO:0015747)
0.0 1.3 GO:0008340 determination of adult lifespan(GO:0008340)
0.0 0.2 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.0 0.6 GO:2000671 regulation of motor neuron apoptotic process(GO:2000671)
0.0 0.7 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.4 GO:0090520 sphingolipid mediated signaling pathway(GO:0090520)
0.0 0.3 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 0.3 GO:0035865 response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865)
0.0 0.8 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.2 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 1.7 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.0 0.4 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.4 GO:0070474 positive regulation of uterine smooth muscle contraction(GO:0070474)
0.0 0.8 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.4 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.1 GO:1901994 negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.0 0.6 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 0.1 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.0 0.4 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.6 GO:0001553 luteinization(GO:0001553)
0.0 1.3 GO:0006284 base-excision repair(GO:0006284)
0.0 0.1 GO:1904566 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.0 0.2 GO:0051612 negative regulation of neurotransmitter uptake(GO:0051581) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:0010360 negative regulation of anion channel activity(GO:0010360)
0.0 0.4 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.2 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.1 GO:0060060 post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.0 0.1 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.0 0.1 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.1 GO:1904124 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.0 2.6 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.0 0.1 GO:0070447 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.0 0.2 GO:0014029 neural crest formation(GO:0014029)
0.0 0.2 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.1 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878) positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0 0.1 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.0 0.1 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.0 0.5 GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880)
0.0 1.6 GO:1900181 negative regulation of protein localization to nucleus(GO:1900181)
0.0 0.1 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.4 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.1 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.0 0.1 GO:2000138 positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.0 0.2 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.1 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.8 GO:0071953 elastic fiber(GO:0071953)
0.1 1.8 GO:0071439 clathrin complex(GO:0071439)
0.1 1.3 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 0.5 GO:0031523 Myb complex(GO:0031523)
0.1 0.3 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.1 2.0 GO:0031045 dense core granule(GO:0031045)
0.1 0.3 GO:0060205 secretory granule lumen(GO:0034774) cytoplasmic membrane-bounded vesicle lumen(GO:0060205)
0.1 0.3 GO:0060187 cell pole(GO:0060187)
0.1 1.7 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 0.4 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 0.2 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.1 0.7 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 1.4 GO:0005859 muscle myosin complex(GO:0005859) myosin filament(GO:0032982)
0.0 1.1 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.2 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.2 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 1.7 GO:0097440 apical dendrite(GO:0097440)
0.0 0.7 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.5 GO:0097542 ciliary tip(GO:0097542)
0.0 3.6 GO:0005882 intermediate filament(GO:0005882)
0.0 0.6 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.2 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 3.4 GO:0000792 heterochromatin(GO:0000792)
0.0 0.1 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.0 0.5 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.2 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 2.2 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.4 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.2 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.1 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.4 GO:0032839 dendrite cytoplasm(GO:0032839)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.2 1.2 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.1 0.7 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.1 1.3 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.1 0.7 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 0.6 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.1 0.9 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.1 0.5 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.1 0.4 GO:0070644 vitamin D response element binding(GO:0070644)
0.1 0.3 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.1 0.8 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.1 0.4 GO:0042610 CD8 receptor binding(GO:0042610)
0.1 0.7 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 1.4 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 2.2 GO:0042056 chemoattractant activity(GO:0042056)
0.1 1.7 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 0.4 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.1 0.8 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 2.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0050436 microfibril binding(GO:0050436)
0.0 0.7 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.3 GO:0004359 glutaminase activity(GO:0004359)
0.0 1.7 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.3 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.6 GO:0019865 immunoglobulin binding(GO:0019865)
0.0 0.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.2 GO:0000150 recombinase activity(GO:0000150)
0.0 0.4 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0030519 snoRNP binding(GO:0030519)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 3.5 GO:0005179 hormone activity(GO:0005179)
0.0 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.2 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.4 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.0 0.3 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 1.0 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.4 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 2.8 GO:0003774 motor activity(GO:0003774)
0.0 0.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.3 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.1 GO:1990405 protein antigen binding(GO:1990405)
0.0 0.3 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0 0.7 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.6 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 3.8 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 1.3 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 1.1 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 4.1 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.3 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.5 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 1.6 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.4 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.8 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.2 1.3 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.7 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.7 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.4 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 1.5 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.6 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.3 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.3 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.2 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.1 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.1 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.3 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 1.3 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)