Motif ID: Myb

Z-value: 2.288


Transcription factors associated with Myb:

Gene SymbolEntrez IDGene Name
Myb ENSMUSG00000019982.8 Myb

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mybmm10_v2_chr10_-_21160925_211609840.812.4e-09Click!


Activity profile for motif Myb.

activity profile for motif Myb


Sorted Z-values histogram for motif Myb

Sorted Z-values for motif Myb



Network of associatons between targets according to the STRING database.



First level regulatory network of Myb

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_+_86078070 23.241 ENSMUST00000032069.5
Add2
adducin 2 (beta)
chr10_+_79886302 17.256 ENSMUST00000046091.5
Elane
elastase, neutrophil expressed
chr11_+_58640394 16.548 ENSMUST00000075084.4
Trim58
tripartite motif-containing 58
chr9_+_72438519 16.071 ENSMUST00000184604.1
Mns1
meiosis-specific nuclear structural protein 1
chr9_+_72438534 15.413 ENSMUST00000034746.8
Mns1
meiosis-specific nuclear structural protein 1
chr17_-_48451510 15.310 ENSMUST00000024794.5
Tspo2
translocator protein 2
chr5_+_123749696 12.150 ENSMUST00000031366.7
Kntc1
kinetochore associated 1
chr11_+_87793470 11.940 ENSMUST00000020779.4
Mpo
myeloperoxidase
chr11_+_87793722 11.239 ENSMUST00000143021.2
Mpo
myeloperoxidase
chr2_-_127831817 11.017 ENSMUST00000028858.7
Bub1
budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae)
chr3_+_146404631 10.871 ENSMUST00000106153.2
ENSMUST00000039021.4
ENSMUST00000106151.1
ENSMUST00000149262.1
Ssx2ip



synovial sarcoma, X breakpoint 2 interacting protein



chr4_-_118437331 10.761 ENSMUST00000006565.6
Cdc20
cell division cycle 20
chr10_+_79879614 10.685 ENSMUST00000006679.8
Prtn3
proteinase 3
chr2_+_118814195 10.382 ENSMUST00000110842.1
Knstrn
kinetochore-localized astrin/SPAG5 binding
chr6_+_124829540 10.286 ENSMUST00000150120.1
Cdca3
cell division cycle associated 3
chr2_+_118814237 9.918 ENSMUST00000028803.7
ENSMUST00000126045.1
Knstrn

kinetochore-localized astrin/SPAG5 binding

chr3_+_146404978 9.680 ENSMUST00000129978.1
Ssx2ip
synovial sarcoma, X breakpoint 2 interacting protein
chr8_-_71723308 9.657 ENSMUST00000125092.1
Fcho1
FCH domain only 1
chr1_-_131138232 9.644 ENSMUST00000016670.7
Dyrk3
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
chr3_+_146404844 9.632 ENSMUST00000106149.1
Ssx2ip
synovial sarcoma, X breakpoint 2 interacting protein
chr17_-_33890539 9.579 ENSMUST00000173386.1
Kifc1
kinesin family member C1
chr17_-_33890584 9.377 ENSMUST00000114361.2
ENSMUST00000173492.1
Kifc1

kinesin family member C1

chr6_-_125191535 9.314 ENSMUST00000043848.4
Ncapd2
non-SMC condensin I complex, subunit D2
chr2_+_118813995 9.202 ENSMUST00000134661.1
Knstrn
kinetochore-localized astrin/SPAG5 binding
chr6_+_124829582 9.120 ENSMUST00000024270.7
Cdca3
cell division cycle associated 3
chr1_-_191575534 9.035 ENSMUST00000027933.5
Dtl
denticleless homolog (Drosophila)
chr14_+_46760526 8.659 ENSMUST00000067426.4
Cdkn3
cyclin-dependent kinase inhibitor 3
chr8_+_83389846 8.378 ENSMUST00000002259.6
Clgn
calmegin
chr1_-_133753681 8.238 ENSMUST00000125659.1
ENSMUST00000165602.2
ENSMUST00000048953.7
Atp2b4


ATPase, Ca++ transporting, plasma membrane 4


chr8_+_83389878 8.222 ENSMUST00000109831.2
Clgn
calmegin
chr1_-_133801031 8.082 ENSMUST00000143567.1
Atp2b4
ATPase, Ca++ transporting, plasma membrane 4
chrX_-_102157065 8.012 ENSMUST00000056904.2
Ercc6l
excision repair cross-complementing rodent repair deficiency complementation group 6 like
chrX_+_134308084 7.962 ENSMUST00000081064.5
ENSMUST00000101251.1
ENSMUST00000129782.1
Cenpi


centromere protein I


chr3_+_116594959 7.888 ENSMUST00000029571.8
Sass6
spindle assembly 6 homolog (C. elegans)
chr9_+_106281061 7.877 ENSMUST00000072206.6
Poc1a
POC1 centriolar protein homolog A (Chlamydomonas)
chr2_+_119047116 7.511 ENSMUST00000152380.1
ENSMUST00000099542.2
Casc5

cancer susceptibility candidate 5

chr17_+_26917091 7.444 ENSMUST00000078961.4
Kifc5b
kinesin family member C5B
chrX_+_56454871 7.358 ENSMUST00000039374.2
ENSMUST00000101553.2
Ddx26b

DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B

chr7_-_127137807 7.229 ENSMUST00000049931.5
Spn
sialophorin
chr5_+_33658567 7.224 ENSMUST00000114426.3
Tacc3
transforming, acidic coiled-coil containing protein 3
chr5_+_33658550 7.161 ENSMUST00000152847.1
Tacc3
transforming, acidic coiled-coil containing protein 3
chr2_+_122637867 7.031 ENSMUST00000110512.3
AA467197
expressed sequence AA467197
chr2_+_122637844 6.984 ENSMUST00000047498.8
AA467197
expressed sequence AA467197
chr1_+_135133272 6.655 ENSMUST00000167080.1
Ptpn7
protein tyrosine phosphatase, non-receptor type 7
chr8_+_83955507 6.630 ENSMUST00000005607.8
Asf1b
ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
chr5_+_33658123 6.613 ENSMUST00000074849.6
ENSMUST00000079534.4
Tacc3

transforming, acidic coiled-coil containing protein 3

chr4_-_44167580 6.552 ENSMUST00000098098.2
Rnf38
ring finger protein 38
chr19_-_41802028 6.388 ENSMUST00000026150.8
ENSMUST00000177495.1
ENSMUST00000163265.1
Arhgap19


Rho GTPase activating protein 19


chr2_-_172370506 6.283 ENSMUST00000109139.1
ENSMUST00000028997.7
ENSMUST00000109140.3
Aurka


aurora kinase A


chr18_+_34625009 6.277 ENSMUST00000166044.1
Kif20a
kinesin family member 20A
chr18_+_60925612 6.006 ENSMUST00000102888.3
ENSMUST00000025519.4
Camk2a

calcium/calmodulin-dependent protein kinase II alpha

chr1_-_45503282 5.950 ENSMUST00000086430.4
Col5a2
collagen, type V, alpha 2
chr2_+_119047129 5.856 ENSMUST00000153300.1
ENSMUST00000028799.5
Casc5

cancer susceptibility candidate 5

chr18_+_34624621 5.758 ENSMUST00000167161.1
Kif20a
kinesin family member 20A
chr4_-_44167905 5.728 ENSMUST00000102934.2
Rnf38
ring finger protein 38
chr11_+_87755567 5.675 ENSMUST00000123700.1
A430104N18Rik
RIKEN cDNA A430104N18 gene
chr1_+_135132693 5.612 ENSMUST00000049449.4
Ptpn7
protein tyrosine phosphatase, non-receptor type 7
chr1_+_57995971 5.563 ENSMUST00000027202.8
Sgol2
shugoshin-like 2 (S. pombe)
chr12_+_32378692 5.541 ENSMUST00000172332.2
Ccdc71l
coiled-coil domain containing 71 like
chr12_+_111971545 5.482 ENSMUST00000079009.5
Tdrd9
tudor domain containing 9
chr6_-_28261907 5.444 ENSMUST00000115320.1
ENSMUST00000123098.1
ENSMUST00000115321.2
ENSMUST00000155494.1
Zfp800



zinc finger protein 800



chr3_+_19644452 5.378 ENSMUST00000029139.7
Trim55
tripartite motif-containing 55
chr18_-_67641329 5.373 ENSMUST00000097542.2
Cep76
centrosomal protein 76
chr17_-_80207299 5.304 ENSMUST00000063417.9
Srsf7
serine/arginine-rich splicing factor 7
chr11_+_104577281 5.254 ENSMUST00000106956.3
Myl4
myosin, light polypeptide 4
chr6_-_131388417 5.037 ENSMUST00000032309.6
ENSMUST00000087865.2
Ybx3

Y box protein 3

chr7_+_28441026 5.036 ENSMUST00000135686.1
Gmfg
glia maturation factor, gamma
chr4_-_44167988 4.952 ENSMUST00000143337.1
Rnf38
ring finger protein 38
chr7_+_118712516 4.927 ENSMUST00000106557.1
Ccp110
centriolar coiled coil protein 110
chr7_+_28440927 4.895 ENSMUST00000078845.6
Gmfg
glia maturation factor, gamma
chr5_+_108132885 4.868 ENSMUST00000047677.7
Ccdc18
coiled-coil domain containing 18
chr5_-_8422695 4.852 ENSMUST00000171808.1
Dbf4
DBF4 homolog (S. cerevisiae)
chr2_+_29890534 4.836 ENSMUST00000113764.3
Odf2
outer dense fiber of sperm tails 2
chr8_-_31918203 4.811 ENSMUST00000073884.4
Nrg1
neuregulin 1
chr5_-_8422582 4.771 ENSMUST00000168500.1
ENSMUST00000002368.9
Dbf4

DBF4 homolog (S. cerevisiae)

chr11_-_33513736 4.733 ENSMUST00000102815.3
Ranbp17
RAN binding protein 17
chr7_-_134225088 4.699 ENSMUST00000067680.4
Adam12
a disintegrin and metallopeptidase domain 12 (meltrin alpha)
chr12_-_84148449 4.692 ENSMUST00000061425.2
Pnma1
paraneoplastic antigen MA1
chr7_+_126862431 4.663 ENSMUST00000132808.1
Hirip3
HIRA interacting protein 3
chr8_+_104250869 4.586 ENSMUST00000034342.5
Cklf
chemokine-like factor
chr7_+_126861947 4.490 ENSMUST00000037248.3
Hirip3
HIRA interacting protein 3
chr15_-_97844254 4.379 ENSMUST00000119670.1
ENSMUST00000116409.2
Hdac7

histone deacetylase 7

chr3_+_30856014 4.378 ENSMUST00000108258.1
ENSMUST00000147697.1
Gpr160

G protein-coupled receptor 160

chr10_+_45577811 4.364 ENSMUST00000037044.6
Hace1
HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1
chr17_-_46202576 4.334 ENSMUST00000024749.7
Polh
polymerase (DNA directed), eta (RAD 30 related)
chr5_+_34949435 4.296 ENSMUST00000030984.7
Rgs12
regulator of G-protein signaling 12
chr4_-_132075250 4.264 ENSMUST00000105970.1
ENSMUST00000105975.1
Epb4.1

erythrocyte protein band 4.1

chr15_-_97844164 4.206 ENSMUST00000120683.1
Hdac7
histone deacetylase 7
chr11_-_120348513 4.032 ENSMUST00000071555.6
Actg1
actin, gamma, cytoplasmic 1
chr1_+_153425162 4.010 ENSMUST00000042373.5
Shcbp1l
Shc SH2-domain binding protein 1-like
chr2_-_152831665 4.004 ENSMUST00000156688.1
ENSMUST00000007803.5
Bcl2l1

BCL2-like 1

chr3_+_103914560 3.735 ENSMUST00000106806.1
Rsbn1
rosbin, round spermatid basic protein 1
chr1_-_167285110 3.700 ENSMUST00000027839.8
Uck2
uridine-cytidine kinase 2
chr8_+_104250925 3.672 ENSMUST00000098464.4
Cklf
chemokine-like factor
chr16_+_34690548 3.648 ENSMUST00000023532.6
Ccdc14
coiled-coil domain containing 14
chr17_-_48409729 3.634 ENSMUST00000160319.1
ENSMUST00000159535.1
ENSMUST00000078800.6
ENSMUST00000046719.7
ENSMUST00000162460.1
Nfya




nuclear transcription factor-Y alpha




chr5_+_96997676 3.596 ENSMUST00000112974.1
ENSMUST00000035635.7
Bmp2k

BMP2 inducible kinase

chr3_+_30855946 3.551 ENSMUST00000108261.1
ENSMUST00000108259.1
ENSMUST00000166278.1
ENSMUST00000046748.6
Gpr160



G protein-coupled receptor 160



chr10_+_127290774 3.524 ENSMUST00000026475.8
ENSMUST00000139091.1
Ddit3

DNA-damage inducible transcript 3

chr8_-_111933761 3.448 ENSMUST00000034429.7
Tmem231
transmembrane protein 231
chr11_-_120348475 3.393 ENSMUST00000062147.7
ENSMUST00000128055.1
Actg1

actin, gamma, cytoplasmic 1

chr8_+_83715177 3.393 ENSMUST00000019576.8
Ddx39
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39
chr5_-_33652296 3.377 ENSMUST00000151081.1
ENSMUST00000101354.3
Slbp

stem-loop binding protein

chr2_+_30416096 3.341 ENSMUST00000113601.3
ENSMUST00000113603.3
Ppp2r4

protein phosphatase 2A, regulatory subunit B (PR 53)

chr11_-_109473220 3.238 ENSMUST00000070872.6
Slc16a6
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr17_+_8849974 3.213 ENSMUST00000115720.1
Pde10a
phosphodiesterase 10A
chr2_+_30416031 3.205 ENSMUST00000042055.3
Ppp2r4
protein phosphatase 2A, regulatory subunit B (PR 53)
chr11_-_33513626 3.199 ENSMUST00000037522.7
Ranbp17
RAN binding protein 17
chr3_+_137864573 3.118 ENSMUST00000174561.1
ENSMUST00000173790.1
H2afz

H2A histone family, member Z

chr11_+_85171096 3.104 ENSMUST00000018623.3
1700125H20Rik
RIKEN cDNA 1700125H20 gene
chrX_+_75514299 3.094 ENSMUST00000114070.3
ENSMUST00000033540.5
Vbp1

von Hippel-Lindau binding protein 1

chr2_-_74578875 3.040 ENSMUST00000134168.1
ENSMUST00000111993.2
ENSMUST00000064503.6
Lnp


limb and neural patterns


chr3_+_103914099 3.038 ENSMUST00000051139.6
ENSMUST00000068879.4
Rsbn1

rosbin, round spermatid basic protein 1

chr11_-_120348091 3.017 ENSMUST00000106215.4
Actg1
actin, gamma, cytoplasmic 1
chr4_-_44168339 2.988 ENSMUST00000045793.8
Rnf38
ring finger protein 38
chr1_+_191821444 2.952 ENSMUST00000027931.7
Nek2
NIMA (never in mitosis gene a)-related expressed kinase 2
chr11_+_104576965 2.944 ENSMUST00000106957.1
Myl4
myosin, light polypeptide 4
chr8_-_24725762 2.889 ENSMUST00000171438.1
ENSMUST00000171611.1
ENSMUST00000033958.7
Adam3


a disintegrin and metallopeptidase domain 3 (cyritestin)


chr4_-_83486178 2.753 ENSMUST00000130626.1
Psip1
PC4 and SFRS1 interacting protein 1
chr2_+_4559742 2.731 ENSMUST00000176828.1
Frmd4a
FERM domain containing 4A
chr7_+_13024120 2.691 ENSMUST00000005705.7
Trim28
tripartite motif-containing 28
chr5_+_90367204 2.687 ENSMUST00000068250.3
Gm9958
predicted gene 9958
chr4_-_83486453 2.667 ENSMUST00000107214.2
ENSMUST00000107215.2
ENSMUST00000030207.8
Psip1


PC4 and SFRS1 interacting protein 1


chr5_-_33652339 2.553 ENSMUST00000075670.6
Slbp
stem-loop binding protein
chr5_-_122372230 2.548 ENSMUST00000031419.5
Fam216a
family with sequence similarity 216, member A
chr1_-_57377476 2.513 ENSMUST00000181949.1
4930558J18Rik
RIKEN cDNA 4930558J18 gene
chr6_-_47594967 2.485 ENSMUST00000081721.6
ENSMUST00000114618.1
ENSMUST00000114616.1
Ezh2


enhancer of zeste homolog 2 (Drosophila)


chr8_+_120537423 2.415 ENSMUST00000118136.1
Gse1
genetic suppressor element 1
chr18_+_56707725 2.392 ENSMUST00000025486.8
Lmnb1
lamin B1
chr2_-_74579379 2.388 ENSMUST00000130586.1
Lnp
limb and neural patterns
chr8_+_83715239 2.339 ENSMUST00000172396.1
Ddx39
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39
chr7_+_92875253 2.320 ENSMUST00000076052.6
Prcp
prolylcarboxypeptidase (angiotensinase C)
chr8_+_83715504 2.310 ENSMUST00000109810.1
Ddx39
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39
chr4_+_110397764 2.246 ENSMUST00000097920.2
ENSMUST00000080744.6
Agbl4

ATP/GTP binding protein-like 4

chr6_+_117906755 2.212 ENSMUST00000170346.1
ENSMUST00000179224.1
ENSMUST00000035493.7
Hnrnpf


heterogeneous nuclear ribonucleoprotein F


chr2_-_120731503 2.201 ENSMUST00000110701.1
ENSMUST00000110700.1
Cdan1

congenital dyserythropoietic anemia, type I (human)

chr1_-_161876656 2.188 ENSMUST00000048377.5
Suco
SUN domain containing ossification factor
chr4_+_110397661 2.138 ENSMUST00000106589.2
ENSMUST00000106587.2
ENSMUST00000106591.1
ENSMUST00000106592.1
Agbl4



ATP/GTP binding protein-like 4



chr4_+_149485215 2.121 ENSMUST00000124413.1
ENSMUST00000141293.1
Lzic

leucine zipper and CTNNBIP1 domain containing

chr10_-_22731336 2.090 ENSMUST00000127698.1
Tbpl1
TATA box binding protein-like 1
chr11_+_69935894 2.090 ENSMUST00000149194.1
Ybx2
Y box protein 2
chr4_-_44168252 2.066 ENSMUST00000145760.1
ENSMUST00000128426.1
Rnf38

ring finger protein 38

chrX_+_151046131 2.050 ENSMUST00000112685.1
Fgd1
FYVE, RhoGEF and PH domain containing 1
chr7_-_45434590 2.036 ENSMUST00000107771.3
ENSMUST00000141761.1
Ruvbl2

RuvB-like protein 2

chr4_-_129742275 2.025 ENSMUST00000066257.5
Khdrbs1
KH domain containing, RNA binding, signal transduction associated 1
chr9_+_107547288 2.022 ENSMUST00000010188.7
Zmynd10
zinc finger, MYND domain containing 10
chr14_+_47472628 2.007 ENSMUST00000095941.2
Fbxo34
F-box protein 34
chr3_+_14533817 1.989 ENSMUST00000169079.1
ENSMUST00000091325.3
Lrrcc1

leucine rich repeat and coiled-coil domain containing 1

chr1_+_191025350 1.985 ENSMUST00000181050.1
A230020J21Rik
RIKEN cDNA A230020J21 gene
chr10_+_127677064 1.934 ENSMUST00000118612.1
ENSMUST00000048099.4
Tmem194

transmembrane protein 194

chr4_-_116627921 1.924 ENSMUST00000030456.7
Nasp
nuclear autoantigenic sperm protein (histone-binding)
chr5_+_108065742 1.914 ENSMUST00000081567.4
ENSMUST00000170319.1
ENSMUST00000112626.1
Mtf2


metal response element binding transcription factor 2


chr7_-_79149042 1.905 ENSMUST00000032825.8
ENSMUST00000107409.3
Mfge8

milk fat globule-EGF factor 8 protein

chr1_+_134289997 1.904 ENSMUST00000027730.4
Myog
myogenin
chr1_+_17727034 1.877 ENSMUST00000159958.1
ENSMUST00000160305.1
ENSMUST00000095075.4
Crispld1


cysteine-rich secretory protein LCCL domain containing 1


chr11_+_29373618 1.868 ENSMUST00000040182.6
ENSMUST00000109477.1
Ccdc88a

coiled coil domain containing 88A

chr10_+_80264942 1.864 ENSMUST00000105362.1
ENSMUST00000105361.3
Dazap1

DAZ associated protein 1

chr13_-_77131276 1.859 ENSMUST00000159300.1
Ankrd32
ankyrin repeat domain 32
chr5_+_122158265 1.856 ENSMUST00000102528.4
ENSMUST00000086294.6
Ppp1cc

protein phosphatase 1, catalytic subunit, gamma isoform

chr8_+_83608175 1.856 ENSMUST00000005620.8
Dnajb1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr2_-_157279519 1.832 ENSMUST00000143663.1
Mroh8
maestro heat-like repeat family member 8
chr17_+_27839974 1.831 ENSMUST00000071006.7
Snrpc
U1 small nuclear ribonucleoprotein C
chr4_-_116627478 1.827 ENSMUST00000081182.4
ENSMUST00000030457.5
Nasp

nuclear autoantigenic sperm protein (histone-binding)

chr9_+_108392820 1.823 ENSMUST00000035234.4
1700102P08Rik
RIKEN cDNA 1700102P08 gene
chr4_+_149485260 1.817 ENSMUST00000030842.7
Lzic
leucine zipper and CTNNBIP1 domain containing
chrX_+_20688379 1.806 ENSMUST00000033380.6
Cdk16
cyclin-dependent kinase 16
chr3_-_17230976 1.800 ENSMUST00000177874.1
Gm5283
predicted gene 5283
chr5_+_108065696 1.790 ENSMUST00000172045.1
Mtf2
metal response element binding transcription factor 2
chr15_-_103239812 1.788 ENSMUST00000118152.1
Cbx5
chromobox 5
chr5_+_137629169 1.760 ENSMUST00000176667.1
Lrch4
leucine-rich repeats and calponin homology (CH) domain containing 4
chr11_+_82892116 1.755 ENSMUST00000018988.5
Fndc8
fibronectin type III domain containing 8
chr15_+_85037062 1.740 ENSMUST00000023069.7
Fam118a
family with sequence similarity 118, member A
chr14_-_118923070 1.739 ENSMUST00000047208.5
Dzip1
DAZ interacting protein 1
chr17_-_6961156 1.737 ENSMUST00000063683.6
Tagap1
T cell activation GTPase activating protein 1
chr7_-_126502312 1.736 ENSMUST00000166682.2
Atxn2l
ataxin 2-like
chr5_+_76588663 1.726 ENSMUST00000121979.1
Cep135
centrosomal protein 135
chr11_+_62847111 1.722 ENSMUST00000150989.1
ENSMUST00000176577.1
Fbxw10

F-box and WD-40 domain protein 10

chr1_+_137966529 1.699 ENSMUST00000182158.1
A430106G13Rik
RIKEN cDNA A430106G13 gene
chr4_+_132535542 1.697 ENSMUST00000094657.3
ENSMUST00000105940.3
ENSMUST00000105939.3
ENSMUST00000150207.1
Dnajc8



DnaJ (Hsp40) homolog, subfamily C, member 8



chr12_+_65075582 1.696 ENSMUST00000058889.4
Fancm
Fanconi anemia, complementation group M
chr12_-_110840905 1.673 ENSMUST00000177224.1
ENSMUST00000084974.4
ENSMUST00000070565.8
Stk30


serine/threonine kinase 30


chr7_-_126502094 1.673 ENSMUST00000179818.1
Atxn2l
ataxin 2-like
chr6_+_117906809 1.671 ENSMUST00000177918.1
ENSMUST00000163168.2
Hnrnpf

heterogeneous nuclear ribonucleoprotein F

chr19_-_37178011 1.667 ENSMUST00000133988.1
Cpeb3
cytoplasmic polyadenylation element binding protein 3
chr11_-_101785252 1.659 ENSMUST00000164750.1
ENSMUST00000107176.1
ENSMUST00000017868.6
Etv4


ets variant gene 4 (E1A enhancer binding protein, E1AF)


chr8_-_107439585 1.656 ENSMUST00000077208.4
Rps26-ps1
ribosomal protein S26, pseudogene 1
chr11_-_116853083 1.656 ENSMUST00000092404.6
Srsf2
serine/arginine-rich splicing factor 2
chr11_-_85139939 1.651 ENSMUST00000108075.2
Usp32
ubiquitin specific peptidase 32
chr6_+_119479668 1.645 ENSMUST00000032094.5
Fbxl14
F-box and leucine-rich repeat protein 14
chr1_-_156939626 1.638 ENSMUST00000063199.6
ENSMUST00000027886.7
ENSMUST00000172057.1
Ralgps2


Ral GEF with PH domain and SH3 binding motif 2


chr3_+_90476121 1.637 ENSMUST00000001042.8
Ilf2
interleukin enhancer binding factor 2
chr11_+_69935796 1.628 ENSMUST00000018698.5
Ybx2
Y box protein 2
chr7_-_126502380 1.628 ENSMUST00000167759.1
Atxn2l
ataxin 2-like
chr2_-_165034821 1.613 ENSMUST00000153905.1
ENSMUST00000040381.8
Ncoa5

nuclear receptor coactivator 5

chr7_-_46179929 1.608 ENSMUST00000033123.6
Abcc8
ATP-binding cassette, sub-family C (CFTR/MRP), member 8
chr13_-_100650981 1.581 ENSMUST00000022136.6
ENSMUST00000177848.1
Rad17

RAD17 homolog (S. pombe)

chr5_-_124862368 1.570 ENSMUST00000036206.7
Ccdc92
coiled-coil domain containing 92
chr4_+_154011731 1.564 ENSMUST00000169622.1
ENSMUST00000030894.8
Lrrc47

leucine rich repeat containing 47

chr8_-_72548224 1.558 ENSMUST00000058534.5
Med26
mediator complex subunit 26
chr4_-_11007635 1.533 ENSMUST00000054776.3
Plekhf2
pleckstrin homology domain containing, family F (with FYVE domain) member 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
7.7 23.2 GO:0002149 hypochlorous acid metabolic process(GO:0002148) hypochlorous acid biosynthetic process(GO:0002149)
6.3 19.0 GO:0072382 minus-end-directed vesicle transport along microtubule(GO:0072382)
5.8 17.3 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079) neutrophil mediated killing of fungus(GO:0070947)
5.4 16.3 GO:0010751 regulation of arginine metabolic process(GO:0000821) negative regulation of nitric oxide mediated signal transduction(GO:0010751) negative regulation of cellular amino acid metabolic process(GO:0045763)
3.7 11.0 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
3.6 10.8 GO:0098763 mitotic cell cycle phase(GO:0098763)
3.3 9.9 GO:0071846 actin filament debranching(GO:0071846)
2.4 7.2 GO:0002884 regulation of type IV hypersensitivity(GO:0001807) negative regulation of acute inflammatory response to antigenic stimulus(GO:0002865) negative regulation of hypersensitivity(GO:0002884) T cell aggregation(GO:0070489)
2.1 10.7 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
2.1 6.3 GO:1905881 positive regulation of oocyte development(GO:0060282) positive regulation of oogenesis(GO:1905881)
1.9 9.6 GO:0035617 stress granule disassembly(GO:0035617)
1.9 9.6 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
1.8 32.5 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
1.7 31.5 GO:0070986 left/right axis specification(GO:0070986)
1.5 6.2 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
1.5 6.0 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
1.3 7.9 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
1.2 21.0 GO:0030953 astral microtubule organization(GO:0030953)
1.2 4.9 GO:0032053 ciliary basal body organization(GO:0032053)
1.2 3.5 GO:2000016 negative regulation of determination of dorsal identity(GO:2000016)
1.2 9.3 GO:0010032 meiotic chromosome condensation(GO:0010032)
1.1 28.2 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
1.0 2.1 GO:0072717 cellular response to actinomycin D(GO:0072717)
1.0 1.0 GO:0061511 centriole elongation(GO:0061511)
1.0 4.0 GO:0046898 response to cycloheximide(GO:0046898)
0.9 1.9 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.9 7.3 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.9 2.7 GO:0045869 negative regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045869)
0.9 23.2 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.9 3.5 GO:0009212 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) dTTP metabolic process(GO:0046075)
0.9 4.3 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.8 2.5 GO:0071707 immunoglobulin heavy chain V-D-J recombination(GO:0071707)
0.8 1.6 GO:1901079 positive regulation of relaxation of muscle(GO:1901079)
0.8 2.3 GO:0002353 plasma kallikrein-kinin cascade(GO:0002353)
0.7 3.7 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.7 3.7 GO:0008655 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.7 4.4 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.7 4.3 GO:0071494 cellular response to UV-C(GO:0071494)
0.7 1.4 GO:0010710 regulation of collagen catabolic process(GO:0010710)
0.7 4.8 GO:0045213 neurotransmitter receptor metabolic process(GO:0045213)
0.7 8.9 GO:0019985 translesion synthesis(GO:0019985)
0.7 6.0 GO:0099004 calmodulin dependent kinase signaling pathway(GO:0099004)
0.6 1.9 GO:0014873 response to muscle activity involved in regulation of muscle adaptation(GO:0014873) response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.6 12.0 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.6 8.6 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.6 1.8 GO:0008358 oocyte construction(GO:0007308) oocyte axis specification(GO:0007309) oocyte anterior/posterior axis specification(GO:0007314) pole plasm assembly(GO:0007315) maternal determination of anterior/posterior axis, embryo(GO:0008358) P granule organization(GO:0030719)
0.6 2.4 GO:1904008 response to monosodium glutamate(GO:1904008) cellular response to monosodium glutamate(GO:1904009)
0.6 5.9 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.6 16.8 GO:0007099 centriole replication(GO:0007099)
0.6 1.7 GO:1900248 negative regulation of cytoplasmic translational elongation(GO:1900248)
0.5 2.6 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.5 2.0 GO:0071898 regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
0.5 2.5 GO:1905424 regulation of Wnt-mediated midbrain dopaminergic neuron differentiation(GO:1905424) positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation(GO:1905426)
0.5 2.0 GO:0032241 positive regulation of nucleobase-containing compound transport(GO:0032241)
0.5 20.9 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.4 3.1 GO:0007021 tubulin complex assembly(GO:0007021)
0.4 1.3 GO:0051866 general adaptation syndrome(GO:0051866)
0.4 1.5 GO:0019659 fermentation(GO:0006113) L(+)-lactate biosynthetic process from pyruvate(GO:0019246) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.4 1.4 GO:0018201 peptidyl-glycine modification(GO:0018201)
0.3 1.4 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.3 10.4 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.3 1.3 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.3 9.7 GO:0048268 clathrin coat assembly(GO:0048268)
0.3 5.8 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.3 1.4 GO:0032472 Golgi calcium ion transport(GO:0032472)
0.3 1.4 GO:0070460 thyroid-stimulating hormone secretion(GO:0070460)
0.3 5.6 GO:0034587 piRNA metabolic process(GO:0034587)
0.3 4.4 GO:2000369 regulation of clathrin-dependent endocytosis(GO:2000369)
0.3 4.9 GO:1905508 protein localization to centrosome(GO:0071539) protein localization to microtubule organizing center(GO:1905508)
0.3 1.0 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.2 8.0 GO:0034508 centromere complex assembly(GO:0034508)
0.2 1.0 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.2 2.3 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.2 1.9 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.2 1.7 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600) regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.2 1.4 GO:0030242 autophagy of peroxisome(GO:0030242) peroxisome disassembly(GO:1905683)
0.2 1.0 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.2 3.2 GO:0046069 cGMP catabolic process(GO:0046069)
0.2 8.3 GO:0048246 macrophage chemotaxis(GO:0048246)
0.2 1.0 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.2 7.9 GO:0033120 positive regulation of RNA splicing(GO:0033120)
0.2 1.1 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.2 0.6 GO:1900368 regulation of RNA interference(GO:1900368)
0.1 20.9 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1 1.0 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.1 0.6 GO:1905664 regulation of calcium ion import across plasma membrane(GO:1905664)
0.1 10.4 GO:0045214 sarcomere organization(GO:0045214)
0.1 2.0 GO:0014029 neural crest formation(GO:0014029)
0.1 1.2 GO:0045759 negative regulation of action potential(GO:0045759)
0.1 3.1 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.1 0.9 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.1 5.2 GO:0048255 mRNA stabilization(GO:0048255)
0.1 6.5 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 0.5 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.1 14.4 GO:0007093 mitotic cell cycle checkpoint(GO:0007093)
0.1 1.7 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.1 1.2 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.1 1.2 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.1 0.6 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.1 1.6 GO:0036159 inner dynein arm assembly(GO:0036159)
0.1 1.9 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.1 0.7 GO:2001170 negative regulation of ATP biosynthetic process(GO:2001170)
0.1 4.7 GO:0002437 inflammatory response to antigenic stimulus(GO:0002437)
0.1 1.0 GO:0090220 telomere localization(GO:0034397) chromosome localization to nuclear envelope involved in homologous chromosome segregation(GO:0090220)
0.1 0.6 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.1 0.2 GO:0045358 negative regulation of interferon-beta biosynthetic process(GO:0045358)
0.1 1.1 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1 3.6 GO:2000036 regulation of stem cell population maintenance(GO:2000036)
0.1 1.8 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.1 1.2 GO:0042249 establishment of planar polarity of embryonic epithelium(GO:0042249)
0.1 2.2 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.1 2.7 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 2.2 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.1 1.2 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.1 0.5 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.1 3.0 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.1 0.8 GO:0045945 positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.1 1.5 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.1 5.5 GO:0043484 regulation of RNA splicing(GO:0043484)
0.1 1.6 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.1 4.1 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.1 1.8 GO:0030252 growth hormone secretion(GO:0030252)
0.1 0.9 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.1 0.8 GO:0042118 endothelial cell activation(GO:0042118) regulation of vascular endothelial growth factor signaling pathway(GO:1900746)
0.1 0.3 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 1.0 GO:0048875 chemical homeostasis within a tissue(GO:0048875)
0.1 1.2 GO:0000070 mitotic sister chromatid segregation(GO:0000070)
0.1 0.7 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 3.5 GO:0060563 neuroepithelial cell differentiation(GO:0060563)
0.0 0.2 GO:0034351 negative regulation of glial cell apoptotic process(GO:0034351)
0.0 8.7 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 0.3 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 1.5 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.4 GO:0044417 translocation of molecules into host(GO:0044417) viral mRNA export from host cell nucleus(GO:0046784) translocation of molecules into other organism involved in symbiotic interaction(GO:0051836)
0.0 1.9 GO:0060325 face morphogenesis(GO:0060325)
0.0 1.5 GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:0000288)
0.0 0.2 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.9 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 1.1 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.0 20.2 GO:0051301 cell division(GO:0051301)
0.0 1.3 GO:1902017 regulation of cilium assembly(GO:1902017)
0.0 0.2 GO:0044772 mitotic cell cycle phase transition(GO:0044772)
0.0 0.7 GO:0051220 cytoplasmic sequestering of protein(GO:0051220)
0.0 0.7 GO:0016486 peptide hormone processing(GO:0016486)
0.0 1.8 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.9 GO:0001541 ovarian follicle development(GO:0001541)
0.0 0.8 GO:0042130 negative regulation of T cell proliferation(GO:0042130)
0.0 3.2 GO:1905039 carboxylic acid transmembrane transport(GO:1905039)
0.0 0.1 GO:0038095 Fc-epsilon receptor signaling pathway(GO:0038095)
0.0 0.0 GO:0010615 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.0 0.6 GO:0006970 response to osmotic stress(GO:0006970)
0.0 1.0 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 0.3 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
4.0 12.1 GO:1990423 RZZ complex(GO:1990423)
3.1 6.3 GO:0042585 germinal vesicle(GO:0042585)
3.1 9.3 GO:0000799 nuclear condensin complex(GO:0000799)
2.8 11.0 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
2.3 23.2 GO:0008290 F-actin capping protein complex(GO:0008290)
2.0 6.0 GO:0005588 collagen type V trimer(GO:0005588)
1.6 7.9 GO:0099524 region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524)
1.4 23.2 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
1.3 7.9 GO:0098536 deuterosome(GO:0098536)
1.3 9.0 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
1.2 3.5 GO:0036488 CHOP-C/EBP complex(GO:0036488)
1.1 35.4 GO:0034451 centriolar satellite(GO:0034451)
0.9 19.0 GO:0031616 spindle pole centrosome(GO:0031616)
0.9 5.5 GO:0071547 piP-body(GO:0071547)
0.8 5.9 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.8 29.5 GO:0035371 microtubule plus-end(GO:0035371)
0.7 14.0 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.6 3.6 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.6 3.5 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.6 4.1 GO:0001940 male pronucleus(GO:0001940)
0.6 1.7 GO:0035061 interchromatin granule(GO:0035061)
0.5 15.9 GO:0097228 sperm principal piece(GO:0097228)
0.5 50.3 GO:0097540 sperm flagellum(GO:0036126) axonemal central pair(GO:0097540) axonemal outer doublet(GO:0097545) A axonemal microtubule(GO:0097649) B axonemal microtubule(GO:0097650) 9+2 motile cilium(GO:0097729) C1 axonemal microtubule(GO:1990719) C2 axonemal microtubule(GO:1990720)
0.5 1.4 GO:1990047 spindle matrix(GO:1990047)
0.4 3.1 GO:0001740 Barr body(GO:0001740)
0.4 10.8 GO:0005680 anaphase-promoting complex(GO:0005680)
0.4 1.6 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.4 3.5 GO:0072687 meiotic spindle(GO:0072687)
0.4 4.1 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.4 4.0 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.4 3.9 GO:0000243 commitment complex(GO:0000243)
0.3 1.4 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.3 2.4 GO:0005638 lamin filament(GO:0005638)
0.3 19.5 GO:0005871 kinesin complex(GO:0005871)
0.3 1.0 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.3 3.1 GO:0016272 prefoldin complex(GO:0016272)
0.3 0.6 GO:0031074 nucleocytoplasmic transport complex(GO:0031074)
0.3 2.0 GO:0097255 R2TP complex(GO:0097255)
0.3 1.8 GO:0071546 pi-body(GO:0071546)
0.3 5.4 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.2 6.1 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.2 2.6 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.2 3.4 GO:0036038 MKS complex(GO:0036038)
0.2 10.5 GO:0043034 costamere(GO:0043034)
0.2 1.4 GO:0005927 muscle tendon junction(GO:0005927)
0.2 1.4 GO:0071438 invadopodium membrane(GO:0071438)
0.2 13.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.2 1.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.2 1.4 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.2 8.2 GO:0031672 A band(GO:0031672)
0.2 19.6 GO:0000776 kinetochore(GO:0000776)
0.2 1.7 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.2 9.5 GO:0005844 polysome(GO:0005844)
0.1 1.7 GO:0031011 Ino80 complex(GO:0031011)
0.1 4.8 GO:0030673 axolemma(GO:0030673)
0.1 1.4 GO:0045298 tubulin complex(GO:0045298)
0.1 17.0 GO:0036064 ciliary basal body(GO:0036064)
0.1 8.5 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 5.0 GO:0005719 nuclear euchromatin(GO:0005719)
0.1 15.5 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 4.3 GO:0097440 apical dendrite(GO:0097440)
0.1 13.5 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 1.9 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.1 1.0 GO:0097346 INO80-type complex(GO:0097346)
0.1 8.4 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 0.9 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.1 0.8 GO:0071439 clathrin complex(GO:0071439)
0.1 1.5 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 0.2 GO:0034657 GID complex(GO:0034657)
0.1 0.2 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.1 0.8 GO:0090576 RNA polymerase III transcription factor complex(GO:0090576)
0.1 0.9 GO:0042405 nuclear inclusion body(GO:0042405)
0.1 27.6 GO:0005813 centrosome(GO:0005813)
0.1 0.9 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 1.1 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 3.9 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 1.4 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 2.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834) GTPase complex(GO:1905360)
0.0 1.6 GO:0016592 mediator complex(GO:0016592) core mediator complex(GO:0070847)
0.0 2.3 GO:0005643 nuclear pore(GO:0005643)
0.0 0.4 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.7 GO:0005605 basal lamina(GO:0005605)
0.0 2.2 GO:0016605 PML body(GO:0016605)
0.0 2.1 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 2.3 GO:0045178 basal part of cell(GO:0045178)
0.0 1.3 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 1.2 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 21.8 GO:0005730 nucleolus(GO:0005730)
0.0 10.6 GO:0031012 extracellular matrix(GO:0031012)
0.0 2.7 GO:0032993 protein-DNA complex(GO:0032993)
0.0 7.1 GO:0043235 receptor complex(GO:0043235)
0.0 5.1 GO:0005635 nuclear envelope(GO:0005635)
0.0 4.1 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.7 GO:0016459 myosin complex(GO:0016459)
0.0 0.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.3 GO:0016235 aggresome(GO:0016235)
0.0 1.5 GO:0030027 lamellipodium(GO:0030027)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 5.9 GO:0071207 histone pre-mRNA stem-loop binding(GO:0071207)
1.8 10.8 GO:0010997 anaphase-promoting complex binding(GO:0010997)
1.4 5.4 GO:0097100 supercoiled DNA binding(GO:0097100)
1.2 4.8 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
1.1 16.3 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.9 11.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.9 8.5 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.8 14.1 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.7 3.7 GO:0004849 uridine kinase activity(GO:0004849)
0.7 2.7 GO:0035851 Krueppel-associated box domain binding(GO:0035851)
0.7 19.5 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.5 6.0 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.5 1.5 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.5 19.1 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.5 1.4 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798)
0.5 3.2 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.5 14.0 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.4 8.6 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.4 3.9 GO:1990446 U1 snRNP binding(GO:1990446)
0.4 4.0 GO:0051434 BH3 domain binding(GO:0051434)
0.4 1.1 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.4 2.5 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.3 6.3 GO:0035174 histone serine kinase activity(GO:0035174)
0.3 2.0 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.3 1.3 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.3 22.5 GO:0030507 spectrin binding(GO:0030507)
0.3 3.8 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.3 1.6 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.3 3.4 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.3 0.9 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.3 19.7 GO:0004601 peroxidase activity(GO:0004601)
0.3 10.7 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.3 1.1 GO:0004092 carnitine O-acetyltransferase activity(GO:0004092)
0.3 2.1 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.3 4.1 GO:1990226 histone methyltransferase binding(GO:1990226)
0.2 19.5 GO:0003777 microtubule motor activity(GO:0003777)
0.2 1.0 GO:0003998 acylphosphatase activity(GO:0003998)
0.2 2.3 GO:0001055 RNA polymerase II activity(GO:0001055)
0.2 0.8 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.2 8.3 GO:0008009 chemokine activity(GO:0008009)
0.2 5.0 GO:0035613 RNA stem-loop binding(GO:0035613)
0.2 0.8 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.2 8.2 GO:0003785 actin monomer binding(GO:0003785)
0.2 0.7 GO:0102490 8-oxo-dGTP phosphohydrolase activity(GO:0102490)
0.2 1.9 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.2 16.3 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.2 3.1 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.2 8.7 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.2 1.6 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.2 0.9 GO:0051425 PTB domain binding(GO:0051425)
0.2 2.1 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.1 1.5 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 1.6 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 4.1 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 4.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 0.5 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 9.9 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.1 12.3 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.1 6.0 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 0.9 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.1 2.0 GO:0008143 poly(A) binding(GO:0008143)
0.1 0.9 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 3.9 GO:0017025 TBP-class protein binding(GO:0017025)
0.1 0.3 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.1 9.9 GO:0004386 helicase activity(GO:0004386)
0.1 1.2 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.1 8.4 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.1 2.4 GO:0043274 phospholipase binding(GO:0043274)
0.1 1.4 GO:0017166 vinculin binding(GO:0017166) muscle alpha-actinin binding(GO:0051371)
0.1 4.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 2.5 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 18.4 GO:0008301 DNA binding, bending(GO:0008301)
0.1 21.0 GO:0008017 microtubule binding(GO:0008017)
0.1 0.7 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 5.4 GO:0048365 Rac GTPase binding(GO:0048365)
0.1 1.0 GO:0044388 small protein activating enzyme binding(GO:0044388)
0.1 1.3 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.1 3.6 GO:0001221 transcription cofactor binding(GO:0001221)
0.1 1.2 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 4.2 GO:0140034 methylated histone binding(GO:0035064) methylation-dependent protein binding(GO:0140034)
0.1 1.2 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 18.2 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.1 3.2 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.1 0.2 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
0.1 1.9 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 3.9 GO:0008013 beta-catenin binding(GO:0008013)
0.0 1.3 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 1.7 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.2 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 1.4 GO:0042054 histone methyltransferase activity(GO:0042054)
0.0 12.2 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 2.7 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.7 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 1.6 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 1.9 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 3.7 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 2.1 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.5 GO:0048156 tau protein binding(GO:0048156)
0.0 3.1 GO:0019905 syntaxin binding(GO:0019905)
0.0 2.7 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.2 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.0 29.6 GO:0019904 protein domain specific binding(GO:0019904)
0.0 0.9 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.9 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.1 GO:0019767 IgE receptor activity(GO:0019767)
0.0 0.6 GO:0005109 frizzled binding(GO:0005109)
0.0 6.0 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 12.0 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 1.2 GO:0044325 ion channel binding(GO:0044325)
0.0 0.7 GO:0003774 motor activity(GO:0003774)
0.0 2.9 GO:0045296 cadherin binding(GO:0045296)
0.0 0.9 GO:0042826 histone deacetylase binding(GO:0042826)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 42.3 PID_AURORA_B_PATHWAY Aurora B signaling
0.6 12.3 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.6 21.0 PID_AURORA_A_PATHWAY Aurora A signaling
0.5 7.2 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.5 23.2 PID_IL23_PATHWAY IL23-mediated signaling events
0.5 23.6 PID_PLK1_PATHWAY PLK1 signaling events
0.4 17.3 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.3 4.8 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.2 10.4 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.2 6.0 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.2 4.0 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.2 12.5 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.1 4.7 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.1 3.6 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.1 8.6 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.1 4.3 PID_ATM_PATHWAY ATM pathway
0.1 6.0 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.1 2.0 PID_MYC_PATHWAY C-MYC pathway
0.1 2.3 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.1 2.8 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.1 7.0 PID_CMYB_PATHWAY C-MYB transcription factor network
0.1 0.9 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 12.9 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 1.1 PID_EPO_PATHWAY EPO signaling pathway
0.1 2.1 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 0.9 PID_FAK_PATHWAY Signaling events mediated by focal adhesion kinase
0.0 1.6 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 1.6 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.8 PID_P53_REGULATION_PATHWAY p53 pathway
0.0 1.4 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.8 PID_THROMBIN_PAR1_PATHWAY PAR1-mediated thrombin signaling events
0.0 0.3 PID_ERBB1_RECEPTOR_PROXIMAL_PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 0.3 PID_BARD1_PATHWAY BARD1 signaling events
0.0 0.2 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 31.0 REACTOME_KINESINS Genes involved in Kinesins
0.8 7.2 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.7 70.7 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.7 5.4 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.6 17.3 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.5 5.9 REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.3 11.5 REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS Genes involved in Activation of ATR in response to replication stress
0.3 6.2 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.3 10.7 REACTOME_MRNA_SPLICING_MINOR_PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.2 4.8 REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.2 7.2 REACTOME_BASIGIN_INTERACTIONS Genes involved in Basigin interactions
0.2 4.0 REACTOME_INFLAMMASOMES Genes involved in Inflammasomes
0.2 6.4 REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.2 3.0 REACTOME_APC_CDC20_MEDIATED_DEGRADATION_OF_NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.2 8.2 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.5 REACTOME_ER_PHAGOSOME_PATHWAY Genes involved in ER-Phagosome pathway
0.1 3.7 REACTOME_PYRIMIDINE_METABOLISM Genes involved in Pyrimidine metabolism
0.1 8.8 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 0.6 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 6.0 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.1 2.3 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.1 6.2 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.1 5.1 REACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.1 3.2 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.1 2.0 REACTOME_EXTENSION_OF_TELOMERES Genes involved in Extension of Telomeres
0.1 1.5 REACTOME_PYRUVATE_METABOLISM Genes involved in Pyruvate metabolism
0.1 3.1 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.1 1.5 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.1 0.6 REACTOME_MICRORNA_MIRNA_BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.1 0.7 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism
0.1 1.9 REACTOME_AMYLOIDS Genes involved in Amyloids
0.1 2.7 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.1 3.7 REACTOME_INWARDLY_RECTIFYING_K_CHANNELS Genes involved in Inwardly rectifying K+ channels
0.1 5.7 REACTOME_MRNA_SPLICING Genes involved in mRNA Splicing
0.0 0.9 REACTOME_NEP_NS2_INTERACTS_WITH_THE_CELLULAR_EXPORT_MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 3.4 REACTOME_DNA_REPAIR Genes involved in DNA Repair
0.0 1.0 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.0 1.0 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.0 0.8 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_2_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 1.1 REACTOME_PEROXISOMAL_LIPID_METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 5.5 REACTOME_G_ALPHA_I_SIGNALLING_EVENTS Genes involved in G alpha (i) signalling events
0.0 2.1 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.0 0.2 REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 3.4 REACTOME_GENERIC_TRANSCRIPTION_PATHWAY Genes involved in Generic Transcription Pathway
0.0 0.3 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.7 REACTOME_CHONDROITIN_SULFATE_DERMATAN_SULFATE_METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 0.9 REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION Genes involved in MHC class II antigen presentation
0.0 2.0 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation