Motif ID: Mybl1

Z-value: 2.000


Transcription factors associated with Mybl1:

Gene SymbolEntrez IDGene Name
Mybl1 ENSMUSG00000025912.10 Mybl1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mybl1mm10_v2_chr1_-_9700209_97003290.465.0e-03Click!


Activity profile for motif Mybl1.

activity profile for motif Mybl1


Sorted Z-values histogram for motif Mybl1

Sorted Z-values for motif Mybl1



Network of associatons between targets according to the STRING database.



First level regulatory network of Mybl1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_+_79886302 22.744 ENSMUST00000046091.5
Elane
elastase, neutrophil expressed
chr19_-_11640828 21.712 ENSMUST00000112984.2
Ms4a3
membrane-spanning 4-domains, subfamily A, member 3
chr14_-_56102458 17.850 ENSMUST00000015583.1
Ctsg
cathepsin G
chr11_+_87793722 17.124 ENSMUST00000143021.2
Mpo
myeloperoxidase
chr11_+_87793470 16.168 ENSMUST00000020779.4
Mpo
myeloperoxidase
chr11_+_58918004 15.524 ENSMUST00000108818.3
ENSMUST00000020792.5
Btnl10

butyrophilin-like 10

chr4_-_119189949 15.201 ENSMUST00000124626.1
Ermap
erythroblast membrane-associated protein
chr4_-_46413486 13.874 ENSMUST00000071096.2
Hemgn
hemogen
chr11_+_58640394 13.511 ENSMUST00000075084.4
Trim58
tripartite motif-containing 58
chr8_+_94172618 12.915 ENSMUST00000034214.6
Mt2
metallothionein 2
chr3_-_106167564 12.393 ENSMUST00000063062.8
Chi3l3
chitinase 3-like 3
chr2_+_84980458 10.172 ENSMUST00000028467.5
Prg2
proteoglycan 2, bone marrow
chr4_-_132533488 9.955 ENSMUST00000152993.1
ENSMUST00000067496.6
Atpif1

ATPase inhibitory factor 1

chr17_+_48247759 9.873 ENSMUST00000048065.5
Trem3
triggering receptor expressed on myeloid cells 3
chr19_-_17356631 9.608 ENSMUST00000174236.1
Gcnt1
glucosaminyl (N-acetyl) transferase 1, core 2
chr2_+_174450678 9.428 ENSMUST00000016399.5
Tubb1
tubulin, beta 1 class VI
chr15_-_96642311 9.427 ENSMUST00000088454.5
Slc38a1
solute carrier family 38, member 1
chr14_+_46760526 9.172 ENSMUST00000067426.4
Cdkn3
cyclin-dependent kinase inhibitor 3
chr12_+_109549157 9.096 ENSMUST00000128458.1
ENSMUST00000150851.1
Meg3

maternally expressed 3

chr17_-_35085609 8.857 ENSMUST00000038507.6
Ly6g6f
lymphocyte antigen 6 complex, locus G6F
chr15_-_103252810 8.559 ENSMUST00000154510.1
Nfe2
nuclear factor, erythroid derived 2
chr2_-_150668198 8.203 ENSMUST00000028944.3
Acss1
acyl-CoA synthetase short-chain family member 1
chr7_+_79660196 8.158 ENSMUST00000035977.7
Ticrr
TOPBP1-interacting checkpoint and replication regulator
chr3_-_69044697 8.061 ENSMUST00000136512.1
ENSMUST00000143454.1
ENSMUST00000107802.1
Trim59


tripartite motif-containing 59


chr2_+_118814195 7.960 ENSMUST00000110842.1
Knstrn
kinetochore-localized astrin/SPAG5 binding
chr6_+_124829540 7.848 ENSMUST00000150120.1
Cdca3
cell division cycle associated 3
chr2_+_118814237 7.676 ENSMUST00000028803.7
ENSMUST00000126045.1
Knstrn

kinetochore-localized astrin/SPAG5 binding

chr3_+_51661167 7.541 ENSMUST00000099106.3
Mgst2
microsomal glutathione S-transferase 2
chr14_+_65806066 7.485 ENSMUST00000139644.1
Pbk
PDZ binding kinase
chr2_+_118813995 7.475 ENSMUST00000134661.1
Knstrn
kinetochore-localized astrin/SPAG5 binding
chrX_-_102157065 7.432 ENSMUST00000056904.2
Ercc6l
excision repair cross-complementing rodent repair deficiency complementation group 6 like
chr11_+_32276400 7.367 ENSMUST00000020531.2
Hba-x
hemoglobin X, alpha-like embryonic chain in Hba complex
chr2_+_163054682 7.212 ENSMUST00000018005.3
Mybl2
myeloblastosis oncogene-like 2
chr11_+_32296489 7.082 ENSMUST00000093207.3
Hba-a2
hemoglobin alpha, adult chain 2
chr6_+_124829582 7.077 ENSMUST00000024270.7
Cdca3
cell division cycle associated 3
chr7_-_4397705 6.970 ENSMUST00000108590.2
Gp6
glycoprotein 6 (platelet)
chr3_+_30856014 6.941 ENSMUST00000108258.1
ENSMUST00000147697.1
Gpr160

G protein-coupled receptor 160

chr11_+_5569679 6.934 ENSMUST00000109856.1
ENSMUST00000109855.1
ENSMUST00000118112.2
Ankrd36


ankyrin repeat domain 36


chr14_-_60086832 6.900 ENSMUST00000080368.5
Atp8a2
ATPase, aminophospholipid transporter-like, class I, type 8A, member 2
chrX_+_136270253 6.703 ENSMUST00000178632.1
ENSMUST00000053540.4
Ngfrap1

nerve growth factor receptor (TNFRSF16) associated protein 1

chr1_+_134182404 6.665 ENSMUST00000153856.1
ENSMUST00000082060.3
ENSMUST00000133701.1
ENSMUST00000132873.1
Chi3l1



chitinase 3-like 1



chr1_+_134182150 6.584 ENSMUST00000156873.1
Chi3l1
chitinase 3-like 1
chr4_-_118437331 6.512 ENSMUST00000006565.6
Cdc20
cell division cycle 20
chr5_+_123749696 6.461 ENSMUST00000031366.7
Kntc1
kinetochore associated 1
chr12_-_99883429 6.260 ENSMUST00000046485.3
Efcab11
EF-hand calcium binding domain 11
chr11_-_72550255 6.173 ENSMUST00000021154.6
Spns3
spinster homolog 3
chr10_+_75573448 5.976 ENSMUST00000006508.3
Ggt1
gamma-glutamyltransferase 1
chr1_-_133753681 5.875 ENSMUST00000125659.1
ENSMUST00000165602.2
ENSMUST00000048953.7
Atp2b4


ATPase, Ca++ transporting, plasma membrane 4


chr4_-_117182623 5.740 ENSMUST00000065896.2
Kif2c
kinesin family member 2C
chr4_-_44167580 5.666 ENSMUST00000098098.2
Rnf38
ring finger protein 38
chr1_+_153751946 5.654 ENSMUST00000183241.1
Rnasel
ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent)
chr7_+_78913765 5.587 ENSMUST00000038142.8
Isg20
interferon-stimulated protein
chr17_-_26095487 5.565 ENSMUST00000025007.5
Nme4
NME/NM23 nucleoside diphosphate kinase 4
chr1_+_57995971 5.550 ENSMUST00000027202.8
Sgol2
shugoshin-like 2 (S. pombe)
chr7_-_127137807 5.375 ENSMUST00000049931.5
Spn
sialophorin
chr4_-_43499608 5.374 ENSMUST00000136005.1
ENSMUST00000054538.6
Arhgef39

Rho guanine nucleotide exchange factor (GEF) 39

chr7_+_126862431 5.345 ENSMUST00000132808.1
Hirip3
HIRA interacting protein 3
chr8_+_83955507 5.323 ENSMUST00000005607.8
Asf1b
ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
chr2_-_170427828 5.265 ENSMUST00000013667.2
ENSMUST00000109152.2
ENSMUST00000068137.4
Bcas1


breast carcinoma amplified sequence 1


chr6_+_30723541 5.252 ENSMUST00000115127.1
Mest
mesoderm specific transcript
chr18_-_35649349 5.206 ENSMUST00000025211.4
Mzb1
marginal zone B and B1 cell-specific protein 1
chr3_+_30855946 5.204 ENSMUST00000108261.1
ENSMUST00000108259.1
ENSMUST00000166278.1
ENSMUST00000046748.6
Gpr160



G protein-coupled receptor 160



chr10_+_79930419 5.192 ENSMUST00000131118.1
Arid3a
AT rich interactive domain 3A (BRIGHT-like)
chr17_-_23645264 5.095 ENSMUST00000024696.7
Mmp25
matrix metallopeptidase 25
chr12_+_69168808 5.085 ENSMUST00000110621.1
Lrr1
leucine rich repeat protein 1
chr2_+_122637844 5.070 ENSMUST00000047498.8
AA467197
expressed sequence AA467197
chrX_+_50841434 5.016 ENSMUST00000114887.2
2610018G03Rik
RIKEN cDNA 2610018G03 gene
chr2_-_35979624 4.996 ENSMUST00000028248.4
ENSMUST00000112976.2
Ttll11

tubulin tyrosine ligase-like family, member 11

chr15_+_79891631 4.994 ENSMUST00000177350.1
ENSMUST00000177483.1
Apobec3

apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3

chr9_+_27030159 4.935 ENSMUST00000073127.7
ENSMUST00000086198.4
Ncapd3

non-SMC condensin II complex, subunit D3

chr3_-_92485886 4.871 ENSMUST00000054599.7
Sprr1a
small proline-rich protein 1A
chr13_+_108316395 4.811 ENSMUST00000171178.1
Depdc1b
DEP domain containing 1B
chr15_-_74983430 4.768 ENSMUST00000023250.4
ENSMUST00000166694.1
Ly6i

lymphocyte antigen 6 complex, locus I

chrX_+_69360294 4.717 ENSMUST00000033532.6
Aff2
AF4/FMR2 family, member 2
chr11_-_69605829 4.712 ENSMUST00000047889.6
Atp1b2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr9_-_39603635 4.574 ENSMUST00000119722.1
AW551984
expressed sequence AW551984
chr6_-_128891105 4.566 ENSMUST00000178918.1
ENSMUST00000160290.1
BC035044

cDNA sequence BC035044

chr11_-_33513736 4.459 ENSMUST00000102815.3
Ranbp17
RAN binding protein 17
chr3_+_10012548 4.411 ENSMUST00000029046.8
Fabp5
fatty acid binding protein 5, epidermal
chr14_-_31577318 4.380 ENSMUST00000112027.2
Colq
collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
chr19_+_60755947 4.327 ENSMUST00000088237.4
Nanos1
nanos homolog 1 (Drosophila)
chr1_-_193370260 4.260 ENSMUST00000016323.4
Camk1g
calcium/calmodulin-dependent protein kinase I gamma
chr2_+_29124106 4.243 ENSMUST00000129544.1
Setx
senataxin
chr9_+_64811313 4.219 ENSMUST00000038890.5
Dennd4a
DENN/MADD domain containing 4A
chr11_-_71033462 4.212 ENSMUST00000156068.2
6330403K07Rik
RIKEN cDNA 6330403K07 gene
chr16_+_93883895 4.204 ENSMUST00000023666.4
ENSMUST00000117099.1
ENSMUST00000142316.1
Chaf1b


chromatin assembly factor 1, subunit B (p60)


chr14_+_65805832 4.178 ENSMUST00000022612.3
Pbk
PDZ binding kinase
chr10_+_79664553 4.041 ENSMUST00000020554.6
Madcam1
mucosal vascular addressin cell adhesion molecule 1
chr8_+_83608175 4.018 ENSMUST00000005620.8
Dnajb1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr13_-_23762378 3.997 ENSMUST00000091701.2
Hist1h3a
histone cluster 1, H3a
chr9_+_96258697 3.992 ENSMUST00000179416.1
Tfdp2
transcription factor Dp 2
chr7_+_99594605 3.952 ENSMUST00000162290.1
Arrb1
arrestin, beta 1
chr13_-_49652714 3.940 ENSMUST00000021818.7
Cenpp
centromere protein P
chr1_-_94052553 3.919 ENSMUST00000027507.6
Pdcd1
programmed cell death 1
chr19_-_41802028 3.902 ENSMUST00000026150.8
ENSMUST00000177495.1
ENSMUST00000163265.1
Arhgap19


Rho GTPase activating protein 19


chr7_+_100285478 3.853 ENSMUST00000057023.5
P4ha3
procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide III
chr7_+_43437073 3.850 ENSMUST00000070518.2
Nkg7
natural killer cell group 7 sequence
chr4_-_44167988 3.816 ENSMUST00000143337.1
Rnf38
ring finger protein 38
chr2_+_172393900 3.808 ENSMUST00000109136.2
Cass4
Cas scaffolding protein family member 4
chr2_+_71117923 3.795 ENSMUST00000028403.2
Cybrd1
cytochrome b reductase 1
chr11_+_58379036 3.787 ENSMUST00000013787.4
ENSMUST00000108826.2
Lypd8

LY6/PLAUR domain containing 8

chr4_-_44167905 3.700 ENSMUST00000102934.2
Rnf38
ring finger protein 38
chr4_+_154869585 3.637 ENSMUST00000079269.7
ENSMUST00000163732.1
ENSMUST00000080559.6
Mmel1


membrane metallo-endopeptidase-like 1


chr12_-_69790660 3.604 ENSMUST00000021377.4
Cdkl1
cyclin-dependent kinase-like 1 (CDC2-related kinase)
chr6_-_57825055 3.588 ENSMUST00000127485.1
Vopp1
vesicular, overexpressed in cancer, prosurvival protein 1
chr18_+_34624621 3.585 ENSMUST00000167161.1
Kif20a
kinesin family member 20A
chr8_-_25091341 3.566 ENSMUST00000125466.1
Plekha2
pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2
chr12_+_111406809 3.556 ENSMUST00000150384.1
A230065H16Rik
RIKEN cDNA A230065H16 gene
chr2_-_164356507 3.526 ENSMUST00000109367.3
Slpi
secretory leukocyte peptidase inhibitor
chr5_-_100562836 3.518 ENSMUST00000097437.2
Plac8
placenta-specific 8
chr8_+_83715504 3.514 ENSMUST00000109810.1
Ddx39
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39
chr1_-_193370225 3.482 ENSMUST00000169907.1
Camk1g
calcium/calmodulin-dependent protein kinase I gamma
chr10_-_79874233 3.472 ENSMUST00000166023.1
ENSMUST00000167707.1
ENSMUST00000165601.1
BC005764


cDNA sequence BC005764


chr17_-_46629420 3.396 ENSMUST00000044442.8
Ptk7
PTK7 protein tyrosine kinase 7
chr11_+_101325063 3.384 ENSMUST00000041095.7
ENSMUST00000107264.1
Aoc2

amine oxidase, copper containing 2 (retina-specific)

chr8_+_86745679 3.377 ENSMUST00000098532.2
Gm10638
predicted gene 10638
chr19_+_4154606 3.350 ENSMUST00000061086.8
Ptprcap
protein tyrosine phosphatase, receptor type, C polypeptide-associated protein
chr17_-_79355082 3.335 ENSMUST00000068958.7
Cdc42ep3
CDC42 effector protein (Rho GTPase binding) 3
chr6_-_57825144 3.306 ENSMUST00000114297.2
Vopp1
vesicular, overexpressed in cancer, prosurvival protein 1
chr1_-_191575534 3.301 ENSMUST00000027933.5
Dtl
denticleless homolog (Drosophila)
chr18_-_73815392 3.296 ENSMUST00000025439.3
Me2
malic enzyme 2, NAD(+)-dependent, mitochondrial
chr5_-_114813943 3.257 ENSMUST00000061251.5
ENSMUST00000112160.3
1500011B03Rik

RIKEN cDNA 1500011B03 gene

chr9_-_95858320 3.222 ENSMUST00000178038.1
1700065D16Rik
RIKEN cDNA 1700065D16 gene
chr1_-_169531447 3.205 ENSMUST00000111368.1
Nuf2
NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr15_-_96642883 3.192 ENSMUST00000088452.4
Slc38a1
solute carrier family 38, member 1
chr19_-_5894100 3.169 ENSMUST00000055911.4
Tigd3
tigger transposable element derived 3
chr6_-_143100028 3.163 ENSMUST00000111758.2
ENSMUST00000171349.1
ENSMUST00000087485.4
C2cd5


C2 calcium-dependent domain containing 5


chr2_+_109280738 3.074 ENSMUST00000028527.7
Kif18a
kinesin family member 18A
chr15_-_78572754 3.067 ENSMUST00000043214.6
Rac2
RAS-related C3 botulinum substrate 2
chr11_-_33513626 3.061 ENSMUST00000037522.7
Ranbp17
RAN binding protein 17
chr11_-_120348475 3.055 ENSMUST00000062147.7
ENSMUST00000128055.1
Actg1

actin, gamma, cytoplasmic 1

chr12_+_111971545 3.035 ENSMUST00000079009.5
Tdrd9
tudor domain containing 9
chr19_-_11623643 3.029 ENSMUST00000164792.1
ENSMUST00000025583.5
Ms4a2

membrane-spanning 4-domains, subfamily A, member 2

chr4_+_100776664 3.022 ENSMUST00000030257.8
ENSMUST00000097955.2
Cachd1

cache domain containing 1

chr2_+_121506715 3.011 ENSMUST00000028676.5
Wdr76
WD repeat domain 76
chr2_+_156840966 3.009 ENSMUST00000109564.1
Tgif2
TGFB-induced factor homeobox 2
chr1_+_180935022 2.974 ENSMUST00000037361.8
Lefty1
left right determination factor 1
chr16_+_10170228 2.970 ENSMUST00000044103.5
Rpl39l
ribosomal protein L39-like
chr2_+_119112793 2.960 ENSMUST00000140939.1
ENSMUST00000028795.3
Rad51

RAD51 homolog

chr11_+_54304005 2.956 ENSMUST00000000145.5
ENSMUST00000138515.1
Acsl6

acyl-CoA synthetase long-chain family member 6

chr4_+_45184815 2.865 ENSMUST00000134280.1
ENSMUST00000044773.5
Frmpd1

FERM and PDZ domain containing 1

chr8_+_83715177 2.856 ENSMUST00000019576.8
Ddx39
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39
chr4_-_43045686 2.850 ENSMUST00000107956.1
ENSMUST00000107957.1
Fam214b

family with sequence similarity 214, member B

chr8_-_105851981 2.841 ENSMUST00000040776.4
Cenpt
centromere protein T
chr11_-_109472611 2.835 ENSMUST00000168740.1
Slc16a6
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr18_+_67800101 2.822 ENSMUST00000025425.5
Cep192
centrosomal protein 192
chr6_-_83536215 2.819 ENSMUST00000075161.5
Actg2
actin, gamma 2, smooth muscle, enteric
chr19_-_42086338 2.809 ENSMUST00000051772.8
Morn4
MORN repeat containing 4
chr11_+_95337012 2.803 ENSMUST00000037502.6
Fam117a
family with sequence similarity 117, member A
chr11_+_98551097 2.794 ENSMUST00000081033.6
ENSMUST00000107511.1
ENSMUST00000107509.1
ENSMUST00000017339.5
Zpbp2



zona pellucida binding protein 2



chr15_-_73184840 2.794 ENSMUST00000044113.10
Ago2
argonaute RISC catalytic subunit 2
chr13_-_117025505 2.773 ENSMUST00000022239.6
Parp8
poly (ADP-ribose) polymerase family, member 8
chr8_+_83715239 2.746 ENSMUST00000172396.1
Ddx39
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39
chr11_+_82892116 2.731 ENSMUST00000018988.5
Fndc8
fibronectin type III domain containing 8
chrX_+_136245065 2.726 ENSMUST00000048687.4
Wbp5
WW domain binding protein 5
chr5_+_123076275 2.662 ENSMUST00000067505.8
ENSMUST00000111619.3
ENSMUST00000160344.1
Tmem120b


transmembrane protein 120B


chr13_-_59769751 2.659 ENSMUST00000057115.6
Isca1
iron-sulfur cluster assembly 1 homolog (S. cerevisiae)
chr6_-_40999479 2.656 ENSMUST00000166306.1
Gm2663
predicted gene 2663
chr1_-_167285110 2.649 ENSMUST00000027839.8
Uck2
uridine-cytidine kinase 2
chr7_-_141279121 2.638 ENSMUST00000167790.1
ENSMUST00000046156.6
Sct

secretin

chr15_-_99251929 2.621 ENSMUST00000041190.9
ENSMUST00000163506.1
Mcrs1

microspherule protein 1

chrX_+_36743659 2.602 ENSMUST00000047655.6
Slc25a43
solute carrier family 25, member 43
chr2_+_31950257 2.598 ENSMUST00000001920.7
Aif1l
allograft inflammatory factor 1-like
chr8_-_68121527 2.593 ENSMUST00000178529.1
Gm21807
predicted gene, 21807
chr15_-_89425795 2.584 ENSMUST00000168376.1
Cpt1b
carnitine palmitoyltransferase 1b, muscle
chr1_-_33669745 2.567 ENSMUST00000027312.9
Prim2
DNA primase, p58 subunit
chr3_-_95995835 2.558 ENSMUST00000143485.1
Plekho1
pleckstrin homology domain containing, family O member 1
chr11_+_68901538 2.556 ENSMUST00000073471.6
ENSMUST00000101014.2
ENSMUST00000128952.1
ENSMUST00000167436.1
Rpl26



ribosomal protein L26



chr4_+_103619580 2.542 ENSMUST00000106827.1
Dab1
disabled 1
chr12_-_114416895 2.534 ENSMUST00000179796.1
Ighv6-5
immunoglobulin heavy variable V6-5
chr1_-_174250976 2.530 ENSMUST00000061990.4
Olfr419
olfactory receptor 419
chr10_+_14523062 2.506 ENSMUST00000096020.5
Gm10335
predicted gene 10335
chr4_-_44168339 2.497 ENSMUST00000045793.8
Rnf38
ring finger protein 38
chr4_-_129558387 2.495 ENSMUST00000067240.4
Lck
lymphocyte protein tyrosine kinase
chr7_-_35537677 2.479 ENSMUST00000127472.1
ENSMUST00000032701.7
Tdrd12

tudor domain containing 12

chr7_+_126861947 2.476 ENSMUST00000037248.3
Hirip3
HIRA interacting protein 3
chr8_-_71272367 2.435 ENSMUST00000110071.2
Haus8
4HAUS augmin-like complex, subunit 8
chr9_+_57827284 2.432 ENSMUST00000163186.1
Gm17231
predicted gene 17231
chr14_-_65425453 2.418 ENSMUST00000059339.5
Pnoc
prepronociceptin
chr13_+_24614608 2.412 ENSMUST00000091694.3
Fam65b
family with sequence similarity 65, member B
chr1_+_40324570 2.397 ENSMUST00000095020.3
Il1rl2
interleukin 1 receptor-like 2
chr4_-_131967824 2.389 ENSMUST00000146443.1
ENSMUST00000135579.1
Epb4.1

erythrocyte protein band 4.1

chr1_+_153425162 2.385 ENSMUST00000042373.5
Shcbp1l
Shc SH2-domain binding protein 1-like
chr8_+_104250869 2.382 ENSMUST00000034342.5
Cklf
chemokine-like factor
chr3_+_153973436 2.376 ENSMUST00000089948.5
Slc44a5
solute carrier family 44, member 5
chr5_+_110286306 2.357 ENSMUST00000007296.5
ENSMUST00000112482.1
Pole

polymerase (DNA directed), epsilon

chr2_+_91650169 2.350 ENSMUST00000090614.4
Arhgap1
Rho GTPase activating protein 1
chr11_-_109473220 2.347 ENSMUST00000070872.6
Slc16a6
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr9_-_15045378 2.323 ENSMUST00000164273.1
Panx1
pannexin 1
chrX_+_135839034 2.319 ENSMUST00000173804.1
ENSMUST00000113136.1
Gprasp2

G protein-coupled receptor associated sorting protein 2

chr17_+_8849974 2.309 ENSMUST00000115720.1
Pde10a
phosphodiesterase 10A
chr2_+_121506748 2.307 ENSMUST00000099473.3
ENSMUST00000110602.2
Wdr76

WD repeat domain 76

chr11_-_43601540 2.275 ENSMUST00000020672.4
Fabp6
fatty acid binding protein 6, ileal (gastrotropin)
chr4_-_129558355 2.272 ENSMUST00000167288.1
ENSMUST00000134336.1
Lck

lymphocyte protein tyrosine kinase

chr16_+_10170216 2.271 ENSMUST00000121292.1
Rpl39l
ribosomal protein L39-like
chr5_+_110514885 2.269 ENSMUST00000141532.1
A630023P12Rik
RIKEN cDNA A630023P12 gene
chr7_-_4812351 2.213 ENSMUST00000079496.7
Ube2s
ubiquitin-conjugating enzyme E2S
chr18_-_62179948 2.213 ENSMUST00000053640.3
Adrb2
adrenergic receptor, beta 2
chr8_-_24948771 2.160 ENSMUST00000119720.1
ENSMUST00000121438.2
Adam32

a disintegrin and metallopeptidase domain 32

chr17_+_29093763 2.155 ENSMUST00000023829.6
Cdkn1a
cyclin-dependent kinase inhibitor 1A (P21)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
11.1 33.3 GO:0002149 hypochlorous acid metabolic process(GO:0002148) hypochlorous acid biosynthetic process(GO:0002149)
7.6 22.7 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079) neutrophil mediated killing of fungus(GO:0070947)
3.9 27.0 GO:0070944 neutrophil mediated cytotoxicity(GO:0070942) neutrophil mediated killing of symbiont cell(GO:0070943) neutrophil mediated killing of bacterium(GO:0070944)
3.5 10.5 GO:0002215 defense response to nematode(GO:0002215)
2.2 6.5 GO:0098763 mitotic cell cycle phase(GO:0098763)
2.0 5.9 GO:0010751 regulation of arginine metabolic process(GO:0000821) negative regulation of nitric oxide mediated signal transduction(GO:0010751) negative regulation of cellular amino acid metabolic process(GO:0045763)
1.8 12.9 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
1.8 12.6 GO:0006868 glutamine transport(GO:0006868)
1.8 5.4 GO:0002884 regulation of type IV hypersensitivity(GO:0001807) negative regulation of acute inflammatory response to antigenic stimulus(GO:0002865) negative regulation of hypersensitivity(GO:0002884) T cell aggregation(GO:0070489)
1.6 6.5 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
1.5 3.1 GO:0071593 lymphocyte aggregation(GO:0071593)
1.4 4.2 GO:0031554 regulation of DNA-templated transcription, termination(GO:0031554)
1.4 6.9 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
1.4 8.2 GO:0006083 acetate metabolic process(GO:0006083)
1.3 3.9 GO:0002644 negative regulation of tolerance induction(GO:0002644)
1.3 23.1 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
1.2 3.6 GO:2001188 negative regulation of immunological synapse formation(GO:2000521) regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001188) negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001189)
1.2 4.7 GO:1903288 positive regulation of potassium ion import(GO:1903288)
1.2 3.5 GO:0070650 actin filament bundle distribution(GO:0070650)
1.1 5.7 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
1.1 5.6 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
1.1 8.7 GO:0015671 oxygen transport(GO:0015671)
1.0 3.1 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
1.0 8.2 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
1.0 9.1 GO:0003011 involuntary skeletal muscle contraction(GO:0003011)
1.0 2.9 GO:1902688 regulation of fermentation(GO:0043465) regulation of NAD metabolic process(GO:1902688) regulation of glucose catabolic process to lactate via pyruvate(GO:1904023)
0.9 4.7 GO:0035063 nuclear speck organization(GO:0035063)
0.9 2.6 GO:0001698 gastrin-induced gastric acid secretion(GO:0001698) positive regulation of somatostatin secretion(GO:0090274)
0.9 2.6 GO:1902162 regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162)
0.8 2.5 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.8 11.6 GO:0060352 cell adhesion molecule production(GO:0060352)
0.8 4.1 GO:0006177 GMP biosynthetic process(GO:0006177)
0.8 2.4 GO:0045004 DNA replication proofreading(GO:0045004)
0.7 6.0 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.7 3.0 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.7 3.0 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.7 8.8 GO:1901030 positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901030)
0.7 4.4 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.7 8.7 GO:0034242 negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.7 4.3 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
0.7 6.6 GO:0051013 microtubule severing(GO:0051013)
0.7 4.0 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.7 3.9 GO:0061644 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641) protein localization to CENP-A containing chromatin(GO:0061644)
0.6 1.9 GO:1902174 striated muscle atrophy(GO:0014891) positive regulation of keratinocyte apoptotic process(GO:1902174)
0.6 5.1 GO:0060022 hard palate development(GO:0060022)
0.6 1.9 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.6 1.9 GO:0002277 myeloid dendritic cell activation involved in immune response(GO:0002277)
0.6 4.9 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.6 3.5 GO:0038095 Fc-epsilon receptor signaling pathway(GO:0038095)
0.6 2.9 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
0.6 0.6 GO:1904882 telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.5 1.6 GO:0071350 interleukin-15-mediated signaling pathway(GO:0035723) extrathymic T cell selection(GO:0045062) cellular response to interleukin-15(GO:0071350) regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.5 2.6 GO:0008655 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.5 2.1 GO:2000705 negative regulation of anion channel activity(GO:0010360) regulation of dense core granule biogenesis(GO:2000705)
0.5 10.4 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.5 5.6 GO:0006183 GTP biosynthetic process(GO:0006183)
0.5 2.0 GO:0071898 regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
0.5 7.5 GO:0019370 leukotriene biosynthetic process(GO:0019370)
0.5 1.0 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.5 2.4 GO:0009597 detection of virus(GO:0009597)
0.5 1.4 GO:0002353 plasma kallikrein-kinin cascade(GO:0002353)
0.5 1.9 GO:0070295 renal water absorption(GO:0070295)
0.5 8.1 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.5 4.8 GO:0046645 positive regulation of gamma-delta T cell differentiation(GO:0045588) positive regulation of gamma-delta T cell activation(GO:0046645)
0.5 3.3 GO:0006108 malate metabolic process(GO:0006108) regulation of NADP metabolic process(GO:1902031)
0.5 0.9 GO:0006271 DNA strand elongation involved in DNA replication(GO:0006271)
0.4 14.0 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.4 1.7 GO:0033580 protein glycosylation at cell surface(GO:0033575) protein galactosylation at cell surface(GO:0033580) protein galactosylation(GO:0042125)
0.4 0.9 GO:0061055 myotome development(GO:0061055)
0.4 2.1 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.4 1.2 GO:0019659 fermentation(GO:0006113) L(+)-lactate biosynthetic process from pyruvate(GO:0019246) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.4 1.6 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.4 2.4 GO:0032439 endosome localization(GO:0032439)
0.4 1.9 GO:1905424 regulation of Wnt-mediated midbrain dopaminergic neuron differentiation(GO:1905424) positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation(GO:1905426)
0.4 3.3 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.4 6.2 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.4 1.1 GO:0046077 dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate metabolic process(GO:0009138) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077)
0.4 2.5 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.4 9.1 GO:0008340 determination of adult lifespan(GO:0008340)
0.3 1.7 GO:0071877 regulation of adrenergic receptor signaling pathway(GO:0071877)
0.3 1.7 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.3 1.0 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.3 4.6 GO:0060923 cardiac muscle cell fate commitment(GO:0060923)
0.3 3.6 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.3 3.2 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.3 1.6 GO:0002803 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.3 1.9 GO:0033058 directional locomotion(GO:0033058)
0.3 2.2 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.3 1.2 GO:0032899 regulation of neurotrophin production(GO:0032899) positive regulation of neurotrophin production(GO:0032901)
0.3 1.2 GO:0060050 positive regulation of protein glycosylation(GO:0060050)
0.3 0.9 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.3 0.9 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.3 1.5 GO:0002238 response to molecule of fungal origin(GO:0002238)
0.3 6.9 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.3 0.9 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.3 1.2 GO:0032241 positive regulation of nucleobase-containing compound transport(GO:0032241)
0.3 1.5 GO:0071033 nuclear retention of pre-mRNA at the site of transcription(GO:0071033)
0.3 2.1 GO:0009235 cobalamin metabolic process(GO:0009235)
0.3 1.5 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.3 1.2 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.3 1.2 GO:0018201 peptidyl-glycine modification(GO:0018201)
0.3 12.1 GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032435)
0.3 0.9 GO:0032240 negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.3 3.4 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.3 0.3 GO:0061188 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.3 1.7 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.3 1.4 GO:0032472 Golgi calcium ion transport(GO:0032472)
0.3 1.0 GO:0014738 regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
0.3 3.1 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.3 0.8 GO:2000314 negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.3 3.3 GO:0019985 translesion synthesis(GO:0019985)
0.3 2.8 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.3 1.8 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.2 3.7 GO:0010528 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.2 2.2 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.2 0.7 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.2 2.8 GO:0034501 protein localization to kinetochore(GO:0034501)
0.2 0.9 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.2 4.7 GO:0001675 acrosome assembly(GO:0001675)
0.2 1.6 GO:0015870 acetylcholine transport(GO:0015870)
0.2 1.4 GO:1902287 trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.2 4.0 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.2 2.2 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.2 1.1 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.2 19.2 GO:0051225 spindle assembly(GO:0051225)
0.2 4.3 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.2 1.4 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.2 0.8 GO:1902167 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902167)
0.2 0.8 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.2 3.8 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.2 3.4 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.2 2.2 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.2 0.9 GO:0086023 adrenergic receptor signaling pathway involved in heart process(GO:0086023)
0.2 2.4 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.2 4.0 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.2 1.3 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336)
0.2 0.9 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.2 1.1 GO:0046755 viral budding(GO:0046755)
0.2 0.7 GO:0035087 targeting of mRNA for destruction involved in RNA interference(GO:0030423) siRNA loading onto RISC involved in RNA interference(GO:0035087)
0.2 3.1 GO:0006999 nuclear pore organization(GO:0006999)
0.2 2.5 GO:0051451 myoblast migration(GO:0051451)
0.2 2.7 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.2 0.5 GO:2000334 response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.2 2.9 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.2 1.1 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.2 2.8 GO:1900153 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.2 0.5 GO:0031446 regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
0.2 0.8 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.2 0.6 GO:0010980 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980) positive regulation of response to extracellular stimulus(GO:0032106) positive regulation of response to nutrient levels(GO:0032109)
0.2 1.7 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.2 0.3 GO:2000412 positive regulation of thymocyte migration(GO:2000412) regulation of immunological synapse formation(GO:2000520)
0.2 1.2 GO:1904867 protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173)
0.1 0.6 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.1 1.6 GO:1901299 negative regulation of hydrogen peroxide-mediated programmed cell death(GO:1901299)
0.1 1.4 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.1 4.9 GO:0031424 keratinization(GO:0031424)
0.1 6.5 GO:0048821 erythrocyte development(GO:0048821)
0.1 2.8 GO:0038092 nodal signaling pathway(GO:0038092)
0.1 4.0 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.1 4.5 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 0.7 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.1 0.5 GO:0070460 thyroid-stimulating hormone secretion(GO:0070460)
0.1 0.4 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861) neuron projection maintenance(GO:1990535)
0.1 2.6 GO:0036065 fucosylation(GO:0036065)
0.1 3.3 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.1 0.3 GO:1903719 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.1 0.9 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
0.1 2.2 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 1.0 GO:0098909 bundle of His cell to Purkinje myocyte signaling(GO:0086028) bundle of His cell action potential(GO:0086043) regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.1 5.8 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.1 0.7 GO:0032346 positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349)
0.1 6.5 GO:0051028 mRNA transport(GO:0051028)
0.1 0.3 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.1 0.3 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.1 0.6 GO:0018002 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.1 0.5 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593)
0.1 0.4 GO:1902255 hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888) positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
0.1 1.1 GO:0000154 rRNA modification(GO:0000154)
0.1 0.6 GO:0071104 response to interleukin-9(GO:0071104)
0.1 0.3 GO:0040010 positive regulation of growth rate(GO:0040010)
0.1 3.4 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.1 0.5 GO:0002200 somatic diversification of immune receptors(GO:0002200) somatic diversification of immunoglobulins(GO:0016445)
0.1 2.2 GO:0044458 motile cilium assembly(GO:0044458)
0.1 0.6 GO:0034227 tRNA thio-modification(GO:0034227)
0.1 0.9 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 0.3 GO:0014877 response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 2.1 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 1.8 GO:0035855 megakaryocyte development(GO:0035855)
0.1 0.3 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.1 2.4 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.1 1.2 GO:0030220 platelet formation(GO:0030220)
0.1 1.2 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.1 1.1 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.1 1.9 GO:0010039 response to iron ion(GO:0010039)
0.1 1.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 0.2 GO:0010159 specification of animal organ position(GO:0010159)
0.1 1.4 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.1 1.5 GO:0007099 centriole replication(GO:0007099)
0.1 1.4 GO:0001553 luteinization(GO:0001553)
0.1 0.4 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.1 0.8 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.1 1.1 GO:0051923 sulfation(GO:0051923)
0.1 1.3 GO:1901642 nucleoside transport(GO:0015858) nucleoside transmembrane transport(GO:1901642)
0.1 3.3 GO:0016601 Rac protein signal transduction(GO:0016601)
0.1 0.4 GO:0071397 cellular response to cholesterol(GO:0071397)
0.1 0.8 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 9.1 GO:0007050 cell cycle arrest(GO:0007050)
0.1 0.9 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.1 0.3 GO:0000237 leptotene(GO:0000237)
0.1 5.3 GO:0032526 response to retinoic acid(GO:0032526)
0.1 0.9 GO:0033623 regulation of integrin activation(GO:0033623)
0.1 0.3 GO:0035385 Roundabout signaling pathway(GO:0035385)
0.1 0.3 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1 2.4 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.1 0.3 GO:0006337 nucleosome disassembly(GO:0006337) protein-DNA complex disassembly(GO:0032986)
0.1 3.2 GO:0045214 sarcomere organization(GO:0045214)
0.1 0.9 GO:0051444 negative regulation of ubiquitin-protein transferase activity(GO:0051444)
0.1 3.0 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.1 1.6 GO:0019731 antibacterial humoral response(GO:0019731)
0.1 0.4 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.6 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 1.0 GO:1901799 negative regulation of proteasomal protein catabolic process(GO:1901799)
0.0 1.1 GO:0006308 DNA catabolic process(GO:0006308)
0.0 2.6 GO:0015909 long-chain fatty acid transport(GO:0015909)
0.0 0.0 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.0 0.5 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.6 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.1 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.0 0.7 GO:0043278 response to morphine(GO:0043278)
0.0 0.2 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.0 0.3 GO:0051026 chiasma assembly(GO:0051026)
0.0 1.1 GO:0030252 growth hormone secretion(GO:0030252)
0.0 3.1 GO:1903047 mitotic cell cycle(GO:0000278) mitotic nuclear division(GO:0140014) mitotic cell cycle process(GO:1903047)
0.0 5.4 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.0 0.4 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 5.1 GO:0045667 regulation of osteoblast differentiation(GO:0045667)
0.0 1.0 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 0.6 GO:0016486 peptide hormone processing(GO:0016486)
0.0 1.3 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.9 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.0 0.1 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.0 0.5 GO:0031643 positive regulation of myelination(GO:0031643)
0.0 0.2 GO:0038169 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.0 1.0 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 0.9 GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 3.6 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.2 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 0.4 GO:1905508 protein localization to centrosome(GO:0071539) protein localization to microtubule organizing center(GO:1905508)
0.0 0.8 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.8 GO:0009583 detection of light stimulus(GO:0009583)
0.0 1.5 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 1.2 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.4 GO:0042772 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.0 0.1 GO:0061314 Notch signaling involved in heart development(GO:0061314)
0.0 3.4 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 1.2 GO:0030199 collagen fibril organization(GO:0030199)
0.0 1.2 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.0 0.8 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.9 GO:0031648 protein destabilization(GO:0031648)
0.0 0.9 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 1.1 GO:0001541 ovarian follicle development(GO:0001541)
0.0 1.0 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.8 GO:1904659 glucose transmembrane transport(GO:1904659)
0.0 0.1 GO:0016191 synaptic vesicle uncoating(GO:0016191) clathrin coat disassembly(GO:0072318) vesicle uncoating(GO:0072319)
0.0 0.1 GO:0060056 mammary gland involution(GO:0060056)
0.0 0.7 GO:0033120 positive regulation of RNA splicing(GO:0033120)
0.0 1.0 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 1.4 GO:0007020 microtubule nucleation(GO:0007020) microtubule polymerization(GO:0046785)
0.0 0.7 GO:0035036 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036)
0.0 2.2 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 1.0 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.0 12.7 GO:0051301 cell division(GO:0051301)
0.0 0.3 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.2 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 1.9 GO:0030177 positive regulation of Wnt signaling pathway(GO:0030177)
0.0 1.6 GO:0001824 blastocyst development(GO:0001824)
0.0 0.3 GO:0051601 exocyst localization(GO:0051601)
0.0 0.4 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.7 GO:0007569 cell aging(GO:0007569)
0.0 0.3 GO:0032366 intracellular sterol transport(GO:0032366) intracellular cholesterol transport(GO:0032367)
0.0 0.0 GO:0007266 Rho protein signal transduction(GO:0007266)
0.0 1.0 GO:0007606 sensory perception of chemical stimulus(GO:0007606)
0.0 0.9 GO:0006342 chromatin silencing(GO:0006342)
0.0 0.2 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.4 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.1 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.0 1.4 GO:2001252 positive regulation of chromosome organization(GO:2001252)
0.0 0.2 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.1 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 1.0 GO:0001649 osteoblast differentiation(GO:0001649)
0.0 0.1 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.0 GO:0071544 diphosphoinositol polyphosphate catabolic process(GO:0071544)
0.0 0.5 GO:0006360 transcription from RNA polymerase I promoter(GO:0006360)
0.0 0.3 GO:0018149 peptide cross-linking(GO:0018149)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 6.5 GO:1990423 RZZ complex(GO:1990423)
2.1 33.0 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
1.8 14.4 GO:0005833 hemoglobin complex(GO:0005833)
1.6 4.9 GO:0000799 nuclear condensin complex(GO:0000799) germinal vesicle(GO:0042585)
1.4 7.2 GO:0031523 Myb complex(GO:0031523)
1.4 4.2 GO:0033186 CAF-1 complex(GO:0033186)
0.8 4.0 GO:0099524 region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524)
0.8 28.9 GO:0035371 microtubule plus-end(GO:0035371)
0.7 1.5 GO:0005642 annulate lamellae(GO:0005642)
0.7 2.2 GO:0070557 PCNA-p21 complex(GO:0070557)
0.6 7.0 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.6 3.1 GO:0005828 kinetochore microtubule(GO:0005828)
0.6 1.2 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.6 3.5 GO:0097513 myosin II filament(GO:0097513)
0.6 6.3 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.5 3.2 GO:0031262 Ndc80 complex(GO:0031262)
0.5 2.6 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.5 4.6 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.5 2.5 GO:1990923 PET complex(GO:1990923)
0.5 2.4 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.5 3.2 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.4 4.9 GO:0000812 Swr1 complex(GO:0000812)
0.4 2.6 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.4 2.9 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.4 2.4 GO:0097443 sorting endosome(GO:0097443)
0.4 1.2 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.4 2.2 GO:0071547 piP-body(GO:0071547)
0.4 2.6 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.4 8.7 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.3 5.9 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.3 3.4 GO:0070545 PeBoW complex(GO:0070545)
0.3 1.0 GO:0035061 interchromatin granule(GO:0035061)
0.3 7.8 GO:0005680 anaphase-promoting complex(GO:0005680)
0.3 2.8 GO:0070578 RISC-loading complex(GO:0070578)
0.3 2.4 GO:0070652 HAUS complex(GO:0070652)
0.3 0.8 GO:1990047 spindle matrix(GO:1990047)
0.3 1.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.3 1.3 GO:0098536 deuterosome(GO:0098536)
0.3 5.1 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.3 1.0 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.2 4.5 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.2 5.5 GO:0000242 pericentriolar material(GO:0000242)
0.2 1.4 GO:0030870 Mre11 complex(GO:0030870)
0.2 1.6 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.2 3.8 GO:0031143 pseudopodium(GO:0031143)
0.2 0.9 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.2 1.9 GO:0030478 actin cap(GO:0030478)
0.2 1.1 GO:0044611 nuclear pore inner ring(GO:0044611)
0.2 1.2 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.2 14.9 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.2 2.7 GO:0031011 Ino80 complex(GO:0031011)
0.2 0.6 GO:0070820 tertiary granule(GO:0070820)
0.2 0.8 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.2 7.3 GO:0000788 nuclear nucleosome(GO:0000788)
0.2 0.8 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.2 2.7 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.2 1.4 GO:0097427 microtubule bundle(GO:0097427)
0.2 3.0 GO:0071819 SAGA complex(GO:0000124) DUBm complex(GO:0071819)
0.2 1.4 GO:0042382 paraspeckles(GO:0042382)
0.2 4.7 GO:0030992 intraciliary transport particle B(GO:0030992)
0.2 22.3 GO:0017053 transcriptional repressor complex(GO:0017053)
0.2 21.6 GO:0097540 sperm flagellum(GO:0036126) axonemal central pair(GO:0097540) axonemal outer doublet(GO:0097545) A axonemal microtubule(GO:0097649) B axonemal microtubule(GO:0097650) 9+2 motile cilium(GO:0097729) C1 axonemal microtubule(GO:1990719) C2 axonemal microtubule(GO:1990720)
0.2 0.7 GO:0070022 transforming growth factor beta receptor complex(GO:0070022)
0.2 7.3 GO:0015030 Cajal body(GO:0015030)
0.2 7.6 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 0.9 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 1.6 GO:0071437 invadopodium(GO:0071437)
0.1 5.1 GO:0001533 cornified envelope(GO:0001533)
0.1 4.8 GO:0090734 site of double-strand break(GO:0035861) site of DNA damage(GO:0090734)
0.1 2.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 0.4 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.1 2.8 GO:0032426 stereocilium tip(GO:0032426)
0.1 9.5 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 0.9 GO:0005664 nuclear origin of replication recognition complex(GO:0005664)
0.1 1.2 GO:0072687 meiotic spindle(GO:0072687)
0.1 0.7 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.1 1.5 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 7.2 GO:0042629 mast cell granule(GO:0042629)
0.1 2.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 1.9 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 2.2 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 8.3 GO:0005643 nuclear pore(GO:0005643)
0.1 0.2 GO:0097255 R2TP complex(GO:0097255)
0.1 1.0 GO:0016589 NURF complex(GO:0016589)
0.1 0.3 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.1 4.8 GO:0005871 kinesin complex(GO:0005871)
0.1 0.3 GO:0044299 C-fiber(GO:0044299)
0.1 7.3 GO:0000776 kinetochore(GO:0000776)
0.1 0.9 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.1 5.8 GO:0031985 Golgi cisterna(GO:0031985)
0.1 9.5 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 3.6 GO:0001772 immunological synapse(GO:0001772)
0.1 0.8 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 0.6 GO:0031415 NatA complex(GO:0031415)
0.1 0.8 GO:0032433 filopodium tip(GO:0032433)
0.1 0.6 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 9.4 GO:0032993 protein-DNA complex(GO:0032993)
0.1 1.1 GO:0071004 U2-type prespliceosome(GO:0071004)
0.1 2.9 GO:0043034 costamere(GO:0043034)
0.1 2.4 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 4.3 GO:0000932 P-body(GO:0000932)
0.1 5.7 GO:0016363 nuclear matrix(GO:0016363)
0.1 0.2 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 0.9 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.9 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 1.7 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.4 GO:0097546 ciliary base(GO:0097546)
0.0 0.5 GO:0016272 prefoldin complex(GO:0016272)
0.0 1.0 GO:0001891 phagocytic cup(GO:0001891)
0.0 1.7 GO:0016592 mediator complex(GO:0016592) core mediator complex(GO:0070847)
0.0 0.3 GO:0071141 SMAD protein complex(GO:0071141)
0.0 1.0 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.3 GO:0034709 methylosome(GO:0034709)
0.0 12.8 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.4 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 11.9 GO:0005925 focal adhesion(GO:0005925)
0.0 0.7 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.0 1.3 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 2.6 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.6 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.3 GO:0071001 U4 snRNP(GO:0005687) U4/U6 x U5 tri-snRNP complex(GO:0046540) U4/U6 snRNP(GO:0071001)
0.0 2.5 GO:0031526 brush border membrane(GO:0031526)
0.0 0.4 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.0 3.5 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.4 GO:0045178 basal part of cell(GO:0045178)
0.0 1.3 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 1.6 GO:0016605 PML body(GO:0016605)
0.0 2.7 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 6.5 GO:0016607 nuclear speck(GO:0016607)
0.0 0.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 1.4 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.7 GO:0019867 mitochondrial outer membrane(GO:0005741) outer membrane(GO:0019867) organelle outer membrane(GO:0031968)
0.0 0.3 GO:0001527 microfibril(GO:0001527)
0.0 7.1 GO:0005874 microtubule(GO:0005874)
0.0 0.3 GO:0000145 exocyst(GO:0000145)
0.0 0.3 GO:0071564 npBAF complex(GO:0071564)
0.0 0.6 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.0 1.7 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 0.5 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 3.1 GO:0005730 nucleolus(GO:0005730)
0.0 0.6 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 9.6 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
2.7 8.2 GO:0003987 acetate-CoA ligase activity(GO:0003987)
2.5 12.6 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
2.0 10.0 GO:0043532 angiostatin binding(GO:0043532)
1.9 7.5 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
1.8 7.1 GO:0031720 haptoglobin binding(GO:0031720)
1.4 4.2 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
1.4 5.6 GO:0008859 exoribonuclease II activity(GO:0008859)
1.3 4.0 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
1.2 5.0 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
1.1 3.4 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936)
1.1 3.4 GO:0052593 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
1.1 3.3 GO:0004473 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
1.1 8.7 GO:0005344 oxygen transporter activity(GO:0005344)
1.1 6.5 GO:0010997 anaphase-promoting complex binding(GO:0010997)
1.1 3.2 GO:0071207 histone pre-mRNA stem-loop binding(GO:0071207)
1.0 4.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
1.0 4.9 GO:0030280 structural constituent of epidermis(GO:0030280)
1.0 4.8 GO:0042610 CD8 receptor binding(GO:0042610)
0.9 9.0 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.9 6.2 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.9 3.5 GO:0019767 IgE receptor activity(GO:0019767)
0.9 10.4 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.8 1.7 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.8 4.0 GO:0098634 protein binding involved in cell-matrix adhesion(GO:0098634)
0.8 2.4 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.7 6.0 GO:0002951 leukotriene-C(4) hydrolase(GO:0002951)
0.7 8.7 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.7 2.2 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.7 7.8 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.7 28.1 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.7 2.1 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.7 8.1 GO:0038064 collagen receptor activity(GO:0038064)
0.7 2.6 GO:0015054 gastrin receptor activity(GO:0015054)
0.6 1.9 GO:0045159 myosin II binding(GO:0045159)
0.6 5.6 GO:1901612 cardiolipin binding(GO:1901612)
0.6 3.0 GO:0038100 nodal binding(GO:0038100)
0.6 33.3 GO:0004601 peroxidase activity(GO:0004601)
0.6 2.2 GO:0031711 beta-adrenergic receptor activity(GO:0004939) bradykinin receptor binding(GO:0031711)
0.5 2.6 GO:0004849 uridine kinase activity(GO:0004849)
0.5 2.6 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.5 2.5 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.5 3.8 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.4 8.8 GO:0051010 microtubule plus-end binding(GO:0051010)
0.4 3.0 GO:0000150 recombinase activity(GO:0000150)
0.4 1.2 GO:0097644 calcitonin receptor activity(GO:0004948) calcitonin binding(GO:0032841) calcitonin family binding(GO:0097644)
0.4 4.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.4 1.6 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.4 2.8 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.4 5.9 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.4 1.9 GO:0015254 glycerol channel activity(GO:0015254)
0.4 2.7 GO:0032027 myosin light chain binding(GO:0032027)
0.4 1.1 GO:0050145 uridylate kinase activity(GO:0009041) nucleoside phosphate kinase activity(GO:0050145)
0.4 2.1 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.3 2.4 GO:0001515 opioid peptide activity(GO:0001515)
0.3 2.0 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.3 2.3 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.3 4.3 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.3 1.7 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.3 0.8 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798)
0.3 1.6 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.3 1.5 GO:0019534 toxin transporter activity(GO:0019534)
0.2 1.6 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.2 2.1 GO:0031419 cobalamin binding(GO:0031419)
0.2 4.3 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.2 0.6 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.2 2.3 GO:0032052 bile acid binding(GO:0032052)
0.2 0.7 GO:0004825 methionine-tRNA ligase activity(GO:0004825)
0.2 0.9 GO:1904288 BAT3 complex binding(GO:1904288)
0.2 3.9 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.2 0.9 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.2 4.5 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.2 0.5 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.2 1.6 GO:0008865 fructokinase activity(GO:0008865)
0.2 1.8 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.2 3.3 GO:0017049 GTP-Rho binding(GO:0017049)
0.2 0.6 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.2 4.8 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.2 2.6 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.2 1.1 GO:0051430 mu-type opioid receptor binding(GO:0031852) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.2 0.9 GO:0035827 rubidium ion transmembrane transporter activity(GO:0035827)
0.1 3.6 GO:0001968 fibronectin binding(GO:0001968)
0.1 1.6 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.1 6.6 GO:0050699 WW domain binding(GO:0050699)
0.1 0.6 GO:0032405 MutLalpha complex binding(GO:0032405)
0.1 5.1 GO:0016504 peptidase activator activity(GO:0016504)
0.1 1.9 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 7.0 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 3.6 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 1.2 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.1 22.8 GO:0008201 heparin binding(GO:0008201)
0.1 6.9 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 2.6 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 2.1 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 0.6 GO:0030620 U2 snRNA binding(GO:0030620)
0.1 1.9 GO:0042608 T cell receptor binding(GO:0042608)
0.1 0.7 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.1 5.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 0.3 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.1 1.5 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) L-serine transporter activity(GO:1905361)
0.1 1.7 GO:0070034 telomerase RNA binding(GO:0070034)
0.1 4.9 GO:0003899 DNA-directed 5'-3' RNA polymerase activity(GO:0003899)
0.1 21.1 GO:0004386 helicase activity(GO:0004386)
0.1 1.0 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 11.5 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 4.5 GO:0005504 fatty acid binding(GO:0005504)
0.1 0.6 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.1 30.4 GO:0008017 microtubule binding(GO:0008017)
0.1 1.4 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 0.9 GO:0008527 taste receptor activity(GO:0008527)
0.1 1.4 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.7 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.1 1.9 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
0.1 0.9 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 0.7 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 5.2 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.1 0.9 GO:0071253 connexin binding(GO:0071253)
0.1 2.7 GO:0008198 ferrous iron binding(GO:0008198)
0.1 5.3 GO:0019843 rRNA binding(GO:0019843)
0.1 2.7 GO:0008009 chemokine activity(GO:0008009)
0.1 1.7 GO:0004935 adrenergic receptor activity(GO:0004935)
0.1 0.2 GO:0003721 telomerase RNA reverse transcriptase activity(GO:0003721)
0.1 0.5 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 1.5 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 1.9 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 0.2 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1 3.7 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 1.3 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.1 2.1 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 1.1 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 0.5 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1 0.9 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.8 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 3.8 GO:0140034 methylated histone binding(GO:0035064) methylation-dependent protein binding(GO:0140034)
0.1 2.2 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 0.9 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 8.3 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 0.9 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 0.4 GO:0070700 BMP receptor binding(GO:0070700)
0.1 7.0 GO:0042393 histone binding(GO:0042393)
0.1 0.7 GO:0048156 tau protein binding(GO:0048156)
0.1 16.8 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.1 1.3 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.1 0.9 GO:0031005 filamin binding(GO:0031005)
0.1 1.4 GO:0016503 pheromone receptor activity(GO:0016503)
0.1 1.0 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.3 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 4.0 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 1.6 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 1.6 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.0 1.6 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.0 1.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.4 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.2 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.0 0.1 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.0 0.7 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.2 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 4.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.2 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.9 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.1 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.9 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.8 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.4 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.8 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 2.0 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 0.3 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 1.6 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.4 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.1 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.0 4.1 GO:0017124 SH3 domain binding(GO:0017124)
0.0 1.4 GO:0097110 scaffold protein binding(GO:0097110)
0.0 1.8 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.3 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.3 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.3 GO:0016889 endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.0 13.5 GO:0003682 chromatin binding(GO:0003682)
0.0 0.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 1.3 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.5 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 3.2 GO:0019887 protein kinase regulator activity(GO:0019887)
0.0 0.7 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.3 GO:0016493 C-C chemokine receptor activity(GO:0016493) C-C chemokine binding(GO:0019957)
0.0 1.3 GO:0005178 integrin binding(GO:0005178)
0.0 0.7 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.3 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.0 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 1.0 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.0 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 1.1 GO:0015297 antiporter activity(GO:0015297)
0.0 0.4 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.7 GO:0042826 histone deacetylase binding(GO:0042826)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 33.0 PID_IL23_PATHWAY IL23-mediated signaling events
0.6 30.2 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.5 5.4 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.3 10.6 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.3 19.1 PID_PLK1_PATHWAY PLK1 signaling events
0.3 3.6 PID_PI3KCI_PATHWAY Class I PI3K signaling events
0.3 13.0 PID_IL8_CXCR2_PATHWAY IL8- and CXCR2-mediated signaling events
0.3 4.0 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.2 4.8 PID_NFKAPPAB_ATYPICAL_PATHWAY Atypical NF-kappaB pathway
0.2 10.2 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.2 5.5 PID_BARD1_PATHWAY BARD1 signaling events
0.1 5.7 PID_AURORA_B_PATHWAY Aurora B signaling
0.1 10.2 PID_E2F_PATHWAY E2F transcription factor network
0.1 5.4 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.1 3.2 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 3.2 SIG_CHEMOTAXIS Genes related to chemotaxis
0.1 4.4 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.1 2.6 SIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.1 1.7 PID_MYC_PATHWAY C-MYC pathway
0.1 0.8 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 2.7 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 5.8 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.1 1.8 PID_AMB2_NEUTROPHILS_PATHWAY amb2 Integrin signaling
0.1 0.8 PID_ANTHRAX_PATHWAY Cellular roles of Anthrax toxin
0.1 1.9 PID_ERBB1_RECEPTOR_PROXIMAL_PATHWAY EGF receptor (ErbB1) signaling pathway
0.1 4.4 PID_P75_NTR_PATHWAY p75(NTR)-mediated signaling
0.1 0.1 ST_INTERLEUKIN_4_PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.3 ST_PAC1_RECEPTOR_PATHWAY PAC1 Receptor Pathway
0.0 0.3 SA_B_CELL_RECEPTOR_COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.4 ST_T_CELL_SIGNAL_TRANSDUCTION T Cell Signal Transduction
0.0 1.1 PID_ATF2_PATHWAY ATF-2 transcription factor network
0.0 1.4 PID_FOXO_PATHWAY FoxO family signaling
0.0 4.6 PID_P53_DOWNSTREAM_PATHWAY Direct p53 effectors
0.0 0.9 PID_THROMBIN_PAR1_PATHWAY PAR1-mediated thrombin signaling events
0.0 1.2 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network
0.0 5.3 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.1 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.0 6.4 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.6 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 0.9 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 4.1 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.4 PID_ARF6_PATHWAY Arf6 signaling events
0.0 0.8 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.0 1.2 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.4 PID_ARF_3PATHWAY Arf1 pathway
0.0 0.1 ST_GRANULE_CELL_SURVIVAL_PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.3 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 43.4 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
1.4 8.2 REACTOME_ETHANOL_OXIDATION Genes involved in Ethanol oxidation
0.5 8.7 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.5 14.0 REACTOME_KINESINS Genes involved in Kinesins
0.5 8.7 REACTOME_PD1_SIGNALING Genes involved in PD-1 signaling
0.4 6.7 REACTOME_CELL_DEATH_SIGNALLING_VIA_NRAGE_NRIF_AND_NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.4 39.1 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.3 1.7 REACTOME_PHOSPHORYLATION_OF_CD3_AND_TCR_ZETA_CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.3 2.6 REACTOME_INHIBITION_OF_REPLICATION_INITIATION_OF_DAMAGED_DNA_BY_RB1_E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.3 7.2 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
0.3 4.1 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.3 10.5 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.3 5.8 REACTOME_EXTENSION_OF_TELOMERES Genes involved in Extension of Telomeres
0.3 3.2 REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.3 9.0 REACTOME_BASIGIN_INTERACTIONS Genes involved in Basigin interactions
0.3 3.4 REACTOME_ASSOCIATION_OF_LICENSING_FACTORS_WITH_THE_PRE_REPLICATIVE_COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.3 11.0 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.3 2.3 REACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS Genes involved in Recycling of bile acids and salts
0.2 4.3 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.2 3.1 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.2 2.4 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.2 6.8 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.2 5.3 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.2 3.0 REACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.2 4.7 REACTOME_THE_ROLE_OF_NEF_IN_HIV1_REPLICATION_AND_DISEASE_PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.2 10.1 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.2 1.9 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.2 3.7 REACTOME_NEP_NS2_INTERACTS_WITH_THE_CELLULAR_EXPORT_MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.1 8.3 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 4.3 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 1.4 REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 2.1 REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.1 3.0 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
0.1 6.6 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 12.9 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 3.1 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 4.0 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 1.2 REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1 1.1 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 2.4 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 0.6 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 2.8 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.1 2.9 REACTOME_G1_PHASE Genes involved in G1 Phase
0.1 0.9 REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 1.6 REACTOME_GLUCOSE_TRANSPORT Genes involved in Glucose transport
0.1 1.9 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 1.2 REACTOME_PYRUVATE_METABOLISM Genes involved in Pyruvate metabolism
0.1 1.9 REACTOME_UNBLOCKING_OF_NMDA_RECEPTOR_GLUTAMATE_BINDING_AND_ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.1 3.7 REACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS Genes involved in Glucagon-type ligand receptors
0.1 1.9 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 1.4 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.1 3.1 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.1 4.3 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.1 3.3 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.1 0.9 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.1 2.1 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 0.9 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 1.9 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 1.0 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 1.3 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 2.3 REACTOME_IRON_UPTAKE_AND_TRANSPORT Genes involved in Iron uptake and transport
0.0 9.1 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.8 REACTOME_FANCONI_ANEMIA_PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.7 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 1.5 REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 1.4 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 0.5 REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 1.4 REACTOME_MRNA_SPLICING_MINOR_PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.9 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.7 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.0 1.1 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 1.3 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.5 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.0 0.9 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.4 REACTOME_P38MAPK_EVENTS Genes involved in p38MAPK events
0.0 0.5 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.3 REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.8 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.9 REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS Genes involved in G alpha (q) signalling events
0.0 0.3 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.5 REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.3 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.9 REACTOME_CHONDROITIN_SULFATE_DERMATAN_SULFATE_METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 1.2 REACTOME_G_ALPHA_S_SIGNALLING_EVENTS Genes involved in G alpha (s) signalling events
0.0 1.6 REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.3 REACTOME_PYRIMIDINE_METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.2 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation