Motif ID: Myod1

Z-value: 1.664


Transcription factors associated with Myod1:

Gene SymbolEntrez IDGene Name
Myod1 ENSMUSG00000009471.3 Myod1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Myod1mm10_v2_chr7_+_46376467_463764800.678.7e-06Click!


Activity profile for motif Myod1.

activity profile for motif Myod1


Sorted Z-values histogram for motif Myod1

Sorted Z-values for motif Myod1



Network of associatons between targets according to the STRING database.



First level regulatory network of Myod1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_+_23139064 30.790 ENSMUST00000033947.8
Ank1
ankyrin 1, erythroid
chr8_+_23139030 28.956 ENSMUST00000121075.1
Ank1
ankyrin 1, erythroid
chr11_+_58640394 16.638 ENSMUST00000075084.4
Trim58
tripartite motif-containing 58
chr12_+_109459843 11.483 ENSMUST00000173812.1
Dlk1
delta-like 1 homolog (Drosophila)
chr8_+_23139157 10.665 ENSMUST00000174435.1
Ank1
ankyrin 1, erythroid
chr1_-_132390301 10.565 ENSMUST00000132435.1
Tmcc2
transmembrane and coiled-coil domains 2
chr2_-_170406501 10.482 ENSMUST00000154650.1
Bcas1
breast carcinoma amplified sequence 1
chr7_+_142441808 10.289 ENSMUST00000105971.1
ENSMUST00000145287.1
Tnni2

troponin I, skeletal, fast 2

chr12_-_76709997 10.188 ENSMUST00000166101.1
Sptb
spectrin beta, erythrocytic
chr17_+_36869567 10.024 ENSMUST00000060524.9
Trim10
tripartite motif-containing 10
chr11_-_53480178 9.247 ENSMUST00000104955.2
Sowaha
sosondowah ankyrin repeat domain family member A
chr11_+_115899943 9.102 ENSMUST00000152171.1
Smim5
small integral membrane protein 5
chr18_+_34840575 9.062 ENSMUST00000043484.7
Reep2
receptor accessory protein 2
chr11_+_115900125 8.789 ENSMUST00000142089.1
ENSMUST00000131566.1
Smim5

small integral membrane protein 5

chr1_-_75133866 8.713 ENSMUST00000027405.4
Slc23a3
solute carrier family 23 (nucleobase transporters), member 3
chr5_-_107723954 8.116 ENSMUST00000165344.1
Gfi1
growth factor independent 1
chr4_+_46039202 7.744 ENSMUST00000156200.1
Tmod1
tropomodulin 1
chrX_-_7964166 7.639 ENSMUST00000128449.1
Gata1
GATA binding protein 1
chr7_+_127211608 7.473 ENSMUST00000032910.6
Mylpf
myosin light chain, phosphorylatable, fast skeletal muscle
chr17_-_26199008 7.434 ENSMUST00000142410.1
ENSMUST00000120333.1
ENSMUST00000039113.7
Pdia2


protein disulfide isomerase associated 2


chr7_+_110772604 7.427 ENSMUST00000005829.6
Ampd3
adenosine monophosphate deaminase 3
chr17_+_25471564 7.413 ENSMUST00000025002.1
Tekt4
tektin 4
chr9_-_39604124 7.269 ENSMUST00000042485.4
ENSMUST00000141370.1
AW551984

expressed sequence AW551984

chr9_+_121777607 7.066 ENSMUST00000098272.2
Klhl40
kelch-like 40
chr2_+_153492790 7.025 ENSMUST00000109783.1
4930404H24Rik
RIKEN cDNA 4930404H24 gene
chr3_-_116253467 6.890 ENSMUST00000090473.5
Gpr88
G-protein coupled receptor 88
chr11_-_69605829 6.814 ENSMUST00000047889.6
Atp1b2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr7_+_19411086 6.785 ENSMUST00000003643.1
Ckm
creatine kinase, muscle
chr6_+_122391379 6.539 ENSMUST00000043553.3
1700063H04Rik
RIKEN cDNA 1700063H04 gene
chr5_-_73191848 6.488 ENSMUST00000176910.1
Fryl
furry homolog-like (Drosophila)
chr5_+_123076275 6.440 ENSMUST00000067505.8
ENSMUST00000111619.3
ENSMUST00000160344.1
Tmem120b


transmembrane protein 120B


chr11_-_54028090 6.421 ENSMUST00000020586.6
Slc22a4
solute carrier family 22 (organic cation transporter), member 4
chr16_-_16869255 6.394 ENSMUST00000075017.4
Vpreb1
pre-B lymphocyte gene 1
chr16_+_17980565 6.357 ENSMUST00000075371.3
Vpreb2
pre-B lymphocyte gene 2
chr7_+_45639964 6.245 ENSMUST00000148532.1
Mamstr
MEF2 activating motif and SAP domain containing transcriptional regulator
chrX_+_160390684 6.088 ENSMUST00000112408.2
ENSMUST00000112402.1
ENSMUST00000112401.1
ENSMUST00000112400.1
ENSMUST00000112405.2
ENSMUST00000112404.2
ENSMUST00000146805.1
Gpr64






G protein-coupled receptor 64






chr9_-_42124276 5.999 ENSMUST00000060989.8
Sorl1
sortilin-related receptor, LDLR class A repeats-containing
chr2_-_114052804 5.802 ENSMUST00000090269.6
Actc1
actin, alpha, cardiac muscle 1
chr2_-_84822546 5.786 ENSMUST00000028471.5
Smtnl1
smoothelin-like 1
chr2_-_164779721 5.716 ENSMUST00000103095.4
Tnnc2
troponin C2, fast
chr11_+_104577281 5.703 ENSMUST00000106956.3
Myl4
myosin, light polypeptide 4
chrX_-_52613936 5.679 ENSMUST00000114857.1
Gpc3
glypican 3
chr2_+_103969528 5.674 ENSMUST00000123437.1
ENSMUST00000163256.1
Lmo2

LIM domain only 2

chr7_+_142442330 5.673 ENSMUST00000149529.1
Tnni2
troponin I, skeletal, fast 2
chr3_-_152166230 5.622 ENSMUST00000046614.9
Gipc2
GIPC PDZ domain containing family, member 2
chr17_-_35027909 5.574 ENSMUST00000040151.2
Sapcd1
suppressor APC domain containing 1
chr11_-_120648104 5.503 ENSMUST00000026134.2
Myadml2
myeloid-associated differentiation marker-like 2
chrX_-_52613913 5.494 ENSMUST00000069360.7
Gpc3
glypican 3
chr15_-_66831625 5.385 ENSMUST00000164163.1
Sla
src-like adaptor
chrX_-_142306170 5.361 ENSMUST00000134825.2
Kcne1l
potassium voltage-gated channel, Isk-related family, member 1-like, pseudogene
chr10_-_80813486 5.321 ENSMUST00000181039.1
ENSMUST00000180438.1
Jsrp1

junctional sarcoplasmic reticulum protein 1

chr2_+_91035613 5.275 ENSMUST00000111445.3
ENSMUST00000111446.3
ENSMUST00000050323.5
Rapsn


receptor-associated protein of the synapse


chr7_+_67952817 5.261 ENSMUST00000005671.8
Igf1r
insulin-like growth factor I receptor
chr5_-_107726017 5.085 ENSMUST00000159263.2
Gfi1
growth factor independent 1
chr11_+_103171081 5.048 ENSMUST00000042286.5
Fmnl1
formin-like 1
chr8_-_111691002 4.966 ENSMUST00000034435.5
Ctrb1
chymotrypsinogen B1
chr8_-_122460666 4.931 ENSMUST00000006762.5
Snai3
snail homolog 3 (Drosophila)
chr17_-_48432723 4.915 ENSMUST00000046549.3
Apobec2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2
chr16_+_87553313 4.787 ENSMUST00000026700.7
Map3k7cl
Map3k7 C-terminal like
chr7_-_126447642 4.769 ENSMUST00000146973.1
Atp2a1
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr8_+_94977101 4.733 ENSMUST00000179619.1
Gpr56
G protein-coupled receptor 56
chr11_+_104576965 4.694 ENSMUST00000106957.1
Myl4
myosin, light polypeptide 4
chrX_+_49470450 4.657 ENSMUST00000114904.3
Arhgap36
Rho GTPase activating protein 36
chr2_+_122637867 4.640 ENSMUST00000110512.3
AA467197
expressed sequence AA467197
chr1_-_96872165 4.630 ENSMUST00000071985.4
Slco4c1
solute carrier organic anion transporter family, member 4C1
chr2_+_122637844 4.625 ENSMUST00000047498.8
AA467197
expressed sequence AA467197
chrX_-_139871637 4.595 ENSMUST00000033811.7
ENSMUST00000087401.5
Morc4

microrchidia 4

chrX_+_49470555 4.492 ENSMUST00000042444.6
Arhgap36
Rho GTPase activating protein 36
chr2_+_103970115 4.480 ENSMUST00000111143.1
ENSMUST00000138815.1
Lmo2

LIM domain only 2

chr10_-_128400448 4.478 ENSMUST00000167859.1
Slc39a5
solute carrier family 39 (metal ion transporter), member 5
chr3_-_100489324 4.457 ENSMUST00000061455.8
Fam46c
family with sequence similarity 46, member C
chr7_-_83735503 4.436 ENSMUST00000001792.4
Il16
interleukin 16
chr19_+_47178820 4.403 ENSMUST00000111808.3
Neurl1a
neuralized homolog 1A (Drosophila)
chrX_+_101449078 4.345 ENSMUST00000033674.5
Itgb1bp2
integrin beta 1 binding protein 2
chr19_+_60755947 4.329 ENSMUST00000088237.4
Nanos1
nanos homolog 1 (Drosophila)
chr18_+_60963517 4.327 ENSMUST00000115295.2
ENSMUST00000039904.6
Camk2a

calcium/calmodulin-dependent protein kinase II alpha

chr9_+_107975529 4.298 ENSMUST00000035216.4
Uba7
ubiquitin-like modifier activating enzyme 7
chr5_+_105415738 4.283 ENSMUST00000112707.1
Lrrc8b
leucine rich repeat containing 8 family, member B
chr11_-_107716517 4.231 ENSMUST00000021065.5
Cacng1
calcium channel, voltage-dependent, gamma subunit 1
chr2_-_27072175 4.192 ENSMUST00000009358.2
Tmem8c
transmembrane protein 8C
chr4_-_43523388 4.150 ENSMUST00000107913.3
ENSMUST00000030184.5
Tpm2

tropomyosin 2, beta

chr4_-_63172118 4.110 ENSMUST00000030042.2
Kif12
kinesin family member 12
chr1_+_135132693 4.048 ENSMUST00000049449.4
Ptpn7
protein tyrosine phosphatase, non-receptor type 7
chr2_+_103970221 3.941 ENSMUST00000111140.2
ENSMUST00000111139.2
Lmo2

LIM domain only 2

chr4_+_45184815 3.934 ENSMUST00000134280.1
ENSMUST00000044773.5
Frmpd1

FERM and PDZ domain containing 1

chr2_+_152911311 3.909 ENSMUST00000028970.7
Mylk2
myosin, light polypeptide kinase 2, skeletal muscle
chr9_-_57836706 3.885 ENSMUST00000164010.1
ENSMUST00000171444.1
ENSMUST00000098686.3
Arid3b


AT rich interactive domain 3B (BRIGHT-like)


chr13_-_55528511 3.811 ENSMUST00000047877.4
Dok3
docking protein 3
chr1_+_129273344 3.807 ENSMUST00000073527.6
ENSMUST00000040311.7
Thsd7b

thrombospondin, type I, domain containing 7B

chr4_-_133872997 3.790 ENSMUST00000137486.2
Rps6ka1
ribosomal protein S6 kinase polypeptide 1
chr9_-_21963568 3.757 ENSMUST00000006397.5
Epor
erythropoietin receptor
chr7_-_25005895 3.723 ENSMUST00000102858.3
ENSMUST00000080882.6
Atp1a3

ATPase, Na+/K+ transporting, alpha 3 polypeptide

chr1_+_75507077 3.647 ENSMUST00000037330.4
Inha
inhibin alpha
chr4_-_43523746 3.597 ENSMUST00000150592.1
Tpm2
tropomyosin 2, beta
chr1_-_75506331 3.575 ENSMUST00000113567.2
ENSMUST00000113565.2
Obsl1

obscurin-like 1

chr9_+_30942541 3.573 ENSMUST00000068135.6
Adamts8
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 8
chr12_-_115790884 3.528 ENSMUST00000081809.5
Ighv1-73
immunoglobulin heavy variable 1-73
chr10_+_14523062 3.509 ENSMUST00000096020.5
Gm10335
predicted gene 10335
chr1_+_130731963 3.496 ENSMUST00000039323.6
AA986860
expressed sequence AA986860
chr4_+_43957401 3.496 ENSMUST00000030202.7
Glipr2
GLI pathogenesis-related 2
chrX_+_48519245 3.453 ENSMUST00000033430.2
Rab33a
RAB33A, member of RAS oncogene family
chr17_+_47505043 3.444 ENSMUST00000182129.1
ENSMUST00000171031.1
Ccnd3

cyclin D3

chr13_-_117025505 3.427 ENSMUST00000022239.6
Parp8
poly (ADP-ribose) polymerase family, member 8
chr1_+_135836380 3.420 ENSMUST00000178204.1
Tnnt2
troponin T2, cardiac
chr17_+_47505117 3.381 ENSMUST00000183044.1
ENSMUST00000037333.10
Ccnd3

cyclin D3

chr17_+_47505149 3.326 ENSMUST00000183177.1
ENSMUST00000182848.1
Ccnd3

cyclin D3

chr13_+_46418266 3.308 ENSMUST00000037923.3
Rbm24
RNA binding motif protein 24
chr7_-_19421326 3.307 ENSMUST00000047020.1
A930016O22Rik
RIKEN cDNA A930016O22 gene
chr7_+_45216671 3.294 ENSMUST00000134420.1
Tead2
TEA domain family member 2
chr1_+_164062070 3.201 ENSMUST00000097491.3
ENSMUST00000027871.7
Sell

selectin, lymphocyte

chr7_-_142969238 3.188 ENSMUST00000009392.4
ENSMUST00000121862.1
Ascl2

achaete-scute complex homolog 2 (Drosophila)

chr11_+_32205483 3.168 ENSMUST00000121182.1
Snrnp25
small nuclear ribonucleoprotein 25 (U11/U12)
chr17_-_27167759 3.164 ENSMUST00000025046.2
Ip6k3
inositol hexaphosphate kinase 3
chr3_+_103074009 3.152 ENSMUST00000090715.6
Ampd1
adenosine monophosphate deaminase 1
chr17_+_47505211 3.131 ENSMUST00000182935.1
ENSMUST00000182506.1
Ccnd3

cyclin D3

chr4_-_133967235 3.087 ENSMUST00000123234.1
Hmgn2
high mobility group nucleosomal binding domain 2
chr3_+_95588990 3.064 ENSMUST00000177399.1
Golph3l
golgi phosphoprotein 3-like
chr12_+_32378692 3.032 ENSMUST00000172332.2
Ccdc71l
coiled-coil domain containing 71 like
chr11_+_32205411 3.016 ENSMUST00000039601.3
ENSMUST00000149043.1
Snrnp25

small nuclear ribonucleoprotein 25 (U11/U12)

chr6_+_30639218 2.971 ENSMUST00000031806.9
Cpa1
carboxypeptidase A1, pancreatic
chr15_-_78773452 2.937 ENSMUST00000018313.5
Mfng
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr7_-_140900401 2.929 ENSMUST00000026561.8
Cox8b
cytochrome c oxidase subunit VIIIb
chr4_-_140845770 2.885 ENSMUST00000026378.3
Padi1
peptidyl arginine deiminase, type I
chr13_+_91461050 2.881 ENSMUST00000004094.8
ENSMUST00000042122.8
Ssbp2

single-stranded DNA binding protein 2

chr7_-_44524642 2.876 ENSMUST00000165208.2
Mybpc2
myosin binding protein C, fast-type
chr8_+_45885479 2.865 ENSMUST00000034053.5
Pdlim3
PDZ and LIM domain 3
chr8_-_105471481 2.843 ENSMUST00000014990.6
Tppp3
tubulin polymerization-promoting protein family member 3
chr11_-_5803733 2.839 ENSMUST00000020768.3
Pgam2
phosphoglycerate mutase 2
chr7_+_142471838 2.829 ENSMUST00000038946.2
Lsp1
lymphocyte specific 1
chr15_-_77022632 2.810 ENSMUST00000019037.8
ENSMUST00000169226.1
Mb

myoglobin

chr14_-_62292959 2.803 ENSMUST00000063169.8
Dleu7
deleted in lymphocytic leukemia, 7
chr5_+_91517615 2.774 ENSMUST00000040576.9
Parm1
prostate androgen-regulated mucin-like protein 1
chrX_-_53114530 2.755 ENSMUST00000114843.2
Plac1
placental specific protein 1
chr11_+_69965396 2.755 ENSMUST00000018713.6
Cldn7
claudin 7
chr6_-_125494754 2.745 ENSMUST00000032492.8
Cd9
CD9 antigen
chr5_-_67847400 2.743 ENSMUST00000113652.1
ENSMUST00000113651.1
ENSMUST00000037380.8
Atp8a1


ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1


chr2_-_33431324 2.725 ENSMUST00000113158.1
Zbtb34
zinc finger and BTB domain containing 34
chr4_+_43957678 2.722 ENSMUST00000107855.1
Glipr2
GLI pathogenesis-related 2
chr11_-_79146407 2.713 ENSMUST00000018478.4
ENSMUST00000108264.1
Ksr1

kinase suppressor of ras 1

chr8_-_40634750 2.663 ENSMUST00000173957.1
Mtmr7
myotubularin related protein 7
chr7_+_142472080 2.651 ENSMUST00000105966.1
Lsp1
lymphocyte specific 1
chr11_+_96929367 2.642 ENSMUST00000062172.5
Prr15l
proline rich 15-like
chr3_-_126998408 2.628 ENSMUST00000182764.1
ENSMUST00000044443.8
Ank2

ankyrin 2, brain

chr4_-_43523595 2.627 ENSMUST00000107914.3
Tpm2
tropomyosin 2, beta
chr4_-_135573623 2.621 ENSMUST00000105855.1
Grhl3
grainyhead-like 3 (Drosophila)
chr4_-_137430517 2.546 ENSMUST00000102522.4
Cela3b
chymotrypsin-like elastase family, member 3B
chr5_+_34989473 2.536 ENSMUST00000114284.1
ENSMUST00000114285.1
Rgs12

regulator of G-protein signaling 12

chr3_+_146404631 2.512 ENSMUST00000106153.2
ENSMUST00000039021.4
ENSMUST00000106151.1
ENSMUST00000149262.1
Ssx2ip



synovial sarcoma, X breakpoint 2 interacting protein



chr11_-_120551126 2.505 ENSMUST00000026121.2
Ppp1r27
protein phosphatase 1, regulatory subunit 27
chr5_-_67847360 2.499 ENSMUST00000072971.6
Atp8a1
ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
chr13_+_23544052 2.496 ENSMUST00000075558.2
Hist1h3f
histone cluster 1, H3f
chr3_+_137864487 2.495 ENSMUST00000041045.7
H2afz
H2A histone family, member Z
chr11_+_87760533 2.488 ENSMUST00000039627.5
ENSMUST00000100644.3
Bzrap1

benzodiazepine receptor associated protein 1

chr4_+_115088708 2.486 ENSMUST00000171877.1
ENSMUST00000177647.1
ENSMUST00000106548.2
ENSMUST00000030488.2
Pdzk1ip1



PDZK1 interacting protein 1



chr5_+_115011111 2.481 ENSMUST00000031530.5
Sppl3
signal peptide peptidase 3
chr7_+_30422389 2.474 ENSMUST00000108175.1
Nfkbid
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, delta
chr1_+_86021935 2.464 ENSMUST00000052854.6
ENSMUST00000125083.1
ENSMUST00000152501.1
ENSMUST00000113344.1
ENSMUST00000130504.1
ENSMUST00000153247.2
Spata3





spermatogenesis associated 3





chr1_+_180935022 2.462 ENSMUST00000037361.8
Lefty1
left right determination factor 1
chr11_-_70322520 2.451 ENSMUST00000019051.2
Alox12e
arachidonate lipoxygenase, epidermal
chr7_-_131410325 2.450 ENSMUST00000154602.1
Ikzf5
IKAROS family zinc finger 5
chr5_-_24351604 2.448 ENSMUST00000036092.7
Kcnh2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr2_+_174760619 2.430 ENSMUST00000029030.2
Edn3
endothelin 3
chr7_+_122289297 2.404 ENSMUST00000064989.5
ENSMUST00000064921.4
Prkcb

protein kinase C, beta

chr4_-_133967296 2.374 ENSMUST00000105893.1
Hmgn2
high mobility group nucleosomal binding domain 2
chr15_+_78926720 2.361 ENSMUST00000089377.5
Lgals1
lectin, galactose binding, soluble 1
chr9_-_112187766 2.355 ENSMUST00000111872.2
ENSMUST00000164754.2
Arpp21

cyclic AMP-regulated phosphoprotein, 21

chr3_+_95588928 2.354 ENSMUST00000177390.1
ENSMUST00000098861.4
ENSMUST00000060323.5
Golph3l


golgi phosphoprotein 3-like


chr10_-_29699379 2.344 ENSMUST00000092620.4
Gm10275
predicted pseudogene 10275
chrX_-_36989656 2.326 ENSMUST00000060474.7
ENSMUST00000053456.4
ENSMUST00000115239.3
Sept6


septin 6


chr16_+_48994185 2.317 ENSMUST00000117994.1
ENSMUST00000048374.5
C330027C09Rik

RIKEN cDNA C330027C09 gene

chr2_-_62483637 2.310 ENSMUST00000136686.1
ENSMUST00000102733.3
Gcg

glucagon

chr2_+_156840966 2.310 ENSMUST00000109564.1
Tgif2
TGFB-induced factor homeobox 2
chr14_-_20496780 2.309 ENSMUST00000022353.3
Mss51
MSS51 mitochondrial translational activator
chr3_+_146404978 2.303 ENSMUST00000129978.1
Ssx2ip
synovial sarcoma, X breakpoint 2 interacting protein
chr7_-_127993831 2.294 ENSMUST00000033056.3
Pycard
PYD and CARD domain containing
chr9_-_121792478 2.236 ENSMUST00000035110.4
Hhatl
hedgehog acyltransferase-like
chrX_+_159708593 2.212 ENSMUST00000080394.6
Sh3kbp1
SH3-domain kinase binding protein 1
chr3_+_95588960 2.202 ENSMUST00000176674.1
ENSMUST00000177389.1
ENSMUST00000176755.1
Golph3l


golgi phosphoprotein 3-like


chr2_-_153529941 2.200 ENSMUST00000035346.7
8430427H17Rik
RIKEN cDNA 8430427H17 gene
chr17_-_35700520 2.193 ENSMUST00000119825.1
Ddr1
discoidin domain receptor family, member 1
chr11_+_101316917 2.174 ENSMUST00000151385.1
Psme3
proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki)
chr1_+_78310295 2.171 ENSMUST00000036172.8
Sgpp2
sphingosine-1-phosphate phosphotase 2
chr3_-_108210438 2.161 ENSMUST00000117784.1
ENSMUST00000119650.1
ENSMUST00000117409.1
Atxn7l2


ataxin 7-like 2


chr4_+_98923908 2.139 ENSMUST00000169053.1
Usp1
ubiquitin specific peptidase 1
chr7_-_98145472 2.117 ENSMUST00000098281.2
Omp
olfactory marker protein
chr5_-_69542622 2.116 ENSMUST00000031045.6
Yipf7
Yip1 domain family, member 7
chr1_+_87205799 2.113 ENSMUST00000027470.7
Chrng
cholinergic receptor, nicotinic, gamma polypeptide
chr10_+_128909866 2.098 ENSMUST00000026407.7
Cd63
CD63 antigen
chr5_-_135251209 2.097 ENSMUST00000062572.2
Fzd9
frizzled homolog 9 (Drosophila)
chr17_-_23684019 2.089 ENSMUST00000085989.5
Cldn9
claudin 9
chr11_+_101316200 2.052 ENSMUST00000142640.1
ENSMUST00000019470.7
Psme3

proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki)

chr11_+_3983636 2.033 ENSMUST00000078757.1
Gal3st1
galactose-3-O-sulfotransferase 1
chrX_+_140956892 2.033 ENSMUST00000112971.1
Atg4a
autophagy related 4A, cysteine peptidase
chr6_-_29212240 2.008 ENSMUST00000160878.1
ENSMUST00000078155.5
Impdh1

inosine 5'-phosphate dehydrogenase 1

chr13_-_97747373 2.005 ENSMUST00000123535.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr1_-_87156127 1.996 ENSMUST00000160810.1
Ecel1
endothelin converting enzyme-like 1
chr3_+_146404844 1.960 ENSMUST00000106149.1
Ssx2ip
synovial sarcoma, X breakpoint 2 interacting protein
chr5_-_137212389 1.930 ENSMUST00000179412.1
A630081J09Rik
RIKEN cDNA A630081J09 gene
chr11_+_96929260 1.921 ENSMUST00000054311.5
ENSMUST00000107636.3
Prr15l

proline rich 15-like

chr3_+_88616133 1.920 ENSMUST00000176500.1
ENSMUST00000177498.1
Arhgef2

rho/rac guanine nucleotide exchange factor (GEF) 2


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 13.2 GO:0010956 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) regulation of interleukin-6-mediated signaling pathway(GO:0070103)
2.5 7.6 GO:0030221 basophil differentiation(GO:0030221)
2.2 11.2 GO:0072138 mesenchymal cell proliferation involved in ureteric bud development(GO:0072138)
2.2 8.7 GO:0031446 regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
1.9 81.5 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
1.7 6.9 GO:0061743 motor learning(GO:0061743)
1.6 9.4 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
1.5 9.1 GO:0050916 sensory perception of sweet taste(GO:0050916)
1.5 6.0 GO:1903288 positive regulation of potassium ion import(GO:1903288)
1.5 6.0 GO:2001137 positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953) positive regulation of endocytic recycling(GO:2001137)
1.5 4.5 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
1.4 7.1 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
1.3 12.1 GO:0032264 IMP salvage(GO:0032264)
1.3 5.3 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
1.3 3.9 GO:0002277 myeloid dendritic cell activation involved in immune response(GO:0002277)
1.3 3.8 GO:0036018 response to erythropoietin(GO:0036017) cellular response to erythropoietin(GO:0036018) erythropoietin-mediated signaling pathway(GO:0038162)
1.2 3.6 GO:0071846 actin filament debranching(GO:0071846)
1.2 3.6 GO:0070650 actin filament bundle distribution(GO:0070650)
1.1 3.4 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
1.1 12.3 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
1.1 6.4 GO:1902603 carnitine transmembrane transport(GO:1902603)
0.9 0.9 GO:0046643 regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
0.9 5.5 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100) vein smooth muscle contraction(GO:0014826)
0.9 1.8 GO:0050917 sensory perception of umami taste(GO:0050917)
0.8 5.0 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.8 4.9 GO:0006216 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.8 16.8 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.7 3.6 GO:0046882 negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.7 1.5 GO:0035582 sequestering of BMP in extracellular matrix(GO:0035582)
0.7 0.7 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.7 2.1 GO:1990523 bone regeneration(GO:1990523)
0.7 2.7 GO:0060032 notochord regression(GO:0060032)
0.7 5.2 GO:0061092 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.6 6.5 GO:0090527 actin filament reorganization(GO:0090527)
0.6 2.6 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.6 6.5 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.6 29.7 GO:0003009 skeletal muscle contraction(GO:0003009)
0.6 8.3 GO:0060923 cardiac muscle cell fate commitment(GO:0060923)
0.6 1.9 GO:2000567 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.6 3.7 GO:0036376 sodium ion export from cell(GO:0036376)
0.6 2.4 GO:1902303 negative regulation of potassium ion export(GO:1902303)
0.6 1.8 GO:0007521 muscle cell fate determination(GO:0007521)
0.6 5.4 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.6 3.5 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.6 2.9 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.6 7.4 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.6 2.8 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.5 4.3 GO:0099004 calmodulin dependent kinase signaling pathway(GO:0099004)
0.5 1.6 GO:0003345 proepicardium cell migration involved in pericardium morphogenesis(GO:0003345)
0.5 3.2 GO:0010626 negative regulation of Schwann cell proliferation(GO:0010626)
0.5 5.7 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.5 1.5 GO:2000978 auditory receptor cell fate determination(GO:0042668) negative regulation of forebrain neuron differentiation(GO:2000978)
0.5 1.5 GO:0030043 actin filament fragmentation(GO:0030043)
0.5 2.5 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.5 5.0 GO:0051014 actin filament severing(GO:0051014)
0.5 1.5 GO:0051385 response to mineralocorticoid(GO:0051385)
0.5 3.8 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.5 1.4 GO:0036269 swimming behavior(GO:0036269)
0.5 2.7 GO:0030913 paranodal junction assembly(GO:0030913)
0.5 2.7 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.5 3.6 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.4 1.3 GO:0010963 regulation of L-arginine import(GO:0010963)
0.4 2.2 GO:1903059 regulation of protein lipidation(GO:1903059)
0.4 5.3 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.4 4.4 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.4 3.9 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.4 2.1 GO:2000680 regulation of rubidium ion transport(GO:2000680)
0.4 7.4 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.4 2.0 GO:0006177 GMP biosynthetic process(GO:0006177)
0.4 2.8 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.4 1.2 GO:0003032 detection of oxygen(GO:0003032)
0.4 2.8 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.4 2.4 GO:0002317 plasma cell differentiation(GO:0002317)
0.4 10.5 GO:0045780 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.4 7.7 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.4 1.8 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.3 1.4 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.3 2.3 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.3 4.2 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.3 1.0 GO:0033082 regulation of extrathymic T cell differentiation(GO:0033082)
0.3 2.5 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
0.3 1.8 GO:0032808 lacrimal gland development(GO:0032808)
0.3 0.6 GO:1904245 regulation of polynucleotide adenylyltransferase activity(GO:1904245)
0.3 2.6 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.3 1.4 GO:0032423 regulation of mismatch repair(GO:0032423)
0.3 0.8 GO:0061642 chemoattraction of axon(GO:0061642) inner medullary collecting duct development(GO:0072061)
0.3 6.8 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.3 1.6 GO:0006543 glutamine catabolic process(GO:0006543)
0.2 1.0 GO:0033580 protein glycosylation at cell surface(GO:0033575) protein galactosylation at cell surface(GO:0033580) protein galactosylation(GO:0042125)
0.2 4.4 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.2 2.5 GO:0019372 lipoxygenase pathway(GO:0019372)
0.2 1.9 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.2 0.7 GO:1901675 response to methylglyoxal(GO:0051595) negative regulation of histone H3-K27 acetylation(GO:1901675)
0.2 1.1 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.2 2.9 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.2 0.7 GO:0006589 octopamine biosynthetic process(GO:0006589) octopamine metabolic process(GO:0046333)
0.2 1.1 GO:0015820 leucine transport(GO:0015820)
0.2 2.2 GO:0042637 catagen(GO:0042637)
0.2 0.9 GO:0009816 defense response, incompatible interaction(GO:0009814) defense response to bacterium, incompatible interaction(GO:0009816) regulation of defense response to bacterium, incompatible interaction(GO:1902477)
0.2 0.9 GO:0070889 platelet alpha granule organization(GO:0070889)
0.2 1.0 GO:1903609 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.2 2.9 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.2 4.3 GO:1900153 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.2 4.2 GO:0038092 nodal signaling pathway(GO:0038092)
0.2 1.2 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.2 5.3 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.2 5.2 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.2 0.7 GO:0048539 bone marrow development(GO:0048539)
0.2 1.9 GO:0046959 habituation(GO:0046959)
0.2 3.5 GO:0061436 establishment of skin barrier(GO:0061436)
0.2 4.2 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.2 3.3 GO:0048368 lateral mesoderm development(GO:0048368)
0.2 0.7 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.2 0.9 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.2 9.3 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.2 0.3 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.2 2.8 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.2 1.8 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.1 1.5 GO:0035878 nail development(GO:0035878)
0.1 5.8 GO:0045907 positive regulation of vasoconstriction(GO:0045907)
0.1 1.2 GO:0060033 anatomical structure regression(GO:0060033)
0.1 2.2 GO:0006670 sphingosine metabolic process(GO:0006670)
0.1 0.4 GO:0060157 urinary bladder development(GO:0060157)
0.1 2.1 GO:0051195 negative regulation of glycolytic process(GO:0045820) negative regulation of cofactor metabolic process(GO:0051195) negative regulation of coenzyme metabolic process(GO:0051198)
0.1 1.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 1.8 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804)
0.1 1.1 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.1 5.2 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 0.8 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) negative regulation of serotonin uptake(GO:0051612)
0.1 1.9 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.1 5.2 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.1 2.5 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.1 4.5 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.1 13.2 GO:0042100 B cell proliferation(GO:0042100)
0.1 3.2 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.1 1.2 GO:0015824 proline transport(GO:0015824)
0.1 0.7 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.1 5.8 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.1 0.8 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
0.1 1.0 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 0.2 GO:1900739 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.1 0.7 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.1 0.7 GO:0099612 protein localization to axon(GO:0099612)
0.1 0.8 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.1 3.2 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.1 0.4 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.1 0.1 GO:0099548 trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by nitric oxide(GO:0099548)
0.1 0.5 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.1 3.5 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 0.6 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.1 0.5 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.1 2.1 GO:0010830 regulation of myotube differentiation(GO:0010830)
0.1 2.2 GO:0046855 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.1 0.5 GO:0048266 behavioral response to pain(GO:0048266)
0.1 0.7 GO:0042058 regulation of epidermal growth factor receptor signaling pathway(GO:0042058)
0.1 0.6 GO:0060017 parathyroid gland development(GO:0060017)
0.1 1.8 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.1 1.2 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.1 0.4 GO:0098903 regulation of membrane repolarization during action potential(GO:0098903)
0.1 1.6 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.1 1.2 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1 0.5 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.1 1.7 GO:0043496 regulation of protein homodimerization activity(GO:0043496)
0.1 1.0 GO:0080111 DNA demethylation(GO:0080111)
0.1 0.9 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.1 0.4 GO:0051697 protein delipidation(GO:0051697)
0.1 0.5 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.1 0.1 GO:0097360 chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
0.1 2.0 GO:0003016 respiratory system process(GO:0003016)
0.1 0.6 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1 0.3 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.1 2.4 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.1 1.3 GO:0045109 intermediate filament organization(GO:0045109)
0.1 2.1 GO:0046718 viral entry into host cell(GO:0046718)
0.1 2.8 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.1 2.3 GO:2000179 positive regulation of neural precursor cell proliferation(GO:2000179)
0.1 1.0 GO:0060539 diaphragm development(GO:0060539)
0.1 3.1 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 9.6 GO:0006936 muscle contraction(GO:0006936)
0.1 0.3 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
0.1 0.9 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.0 2.3 GO:0042398 cellular modified amino acid biosynthetic process(GO:0042398)
0.0 0.5 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 0.5 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.0 0.5 GO:0042168 heme metabolic process(GO:0042168)
0.0 1.3 GO:0006308 DNA catabolic process(GO:0006308)
0.0 2.4 GO:0044070 regulation of anion transport(GO:0044070)
0.0 0.6 GO:0033008 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.4 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.0 0.3 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.0 0.2 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.0 0.3 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.5 GO:0046498 S-adenosylhomocysteine metabolic process(GO:0046498)
0.0 1.1 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)
0.0 0.6 GO:0006970 response to osmotic stress(GO:0006970)
0.0 0.9 GO:0048745 smooth muscle tissue development(GO:0048745)
0.0 0.8 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0 0.2 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.8 GO:0051764 actin crosslink formation(GO:0051764)
0.0 1.7 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 4.5 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 0.1 GO:1903999 regulation of eating behavior(GO:1903998) negative regulation of eating behavior(GO:1903999)
0.0 0.7 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.2 GO:0010759 positive regulation of macrophage chemotaxis(GO:0010759) positive regulation of macrophage migration(GO:1905523)
0.0 2.0 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.1 GO:0032298 positive regulation of DNA-dependent DNA replication initiation(GO:0032298)
0.0 0.4 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 1.8 GO:2001237 negative regulation of extrinsic apoptotic signaling pathway(GO:2001237)
0.0 0.3 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465)
0.0 1.7 GO:0030433 ubiquitin-dependent ERAD pathway(GO:0030433)
0.0 0.4 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.8 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0 0.4 GO:0006825 copper ion transport(GO:0006825)
0.0 2.1 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.0 0.1 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.3 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0 0.1 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0 0.3 GO:0016082 synaptic vesicle priming(GO:0016082)
0.0 0.9 GO:0007020 microtubule nucleation(GO:0007020) microtubule polymerization(GO:0046785)
0.0 0.7 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839)
0.0 0.5 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.1 GO:0071158 positive regulation of cell cycle arrest(GO:0071158)
0.0 0.1 GO:0010992 ubiquitin recycling(GO:0010992)
0.0 0.5 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.0 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.5 79.6 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
1.4 25.1 GO:0005861 troponin complex(GO:0005861)
1.2 3.6 GO:0043512 inhibin-betaglycan-ActRII complex(GO:0034673) inhibin A complex(GO:0043512)
1.1 3.3 GO:0071149 TEAD-2-YAP complex(GO:0071149)
1.1 9.7 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
1.1 4.2 GO:0008537 proteasome activator complex(GO:0008537)
0.9 4.3 GO:0099524 region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524)
0.8 4.8 GO:0031673 H zone(GO:0031673)
0.8 10.3 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.8 2.3 GO:0005940 septin ring(GO:0005940)
0.6 2.4 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.6 3.6 GO:0097513 myosin II filament(GO:0097513)
0.6 5.3 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.6 2.3 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.6 11.0 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.5 6.5 GO:0005865 striated muscle thin filament(GO:0005865)
0.5 2.1 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.5 29.6 GO:0031672 A band(GO:0031672)
0.4 2.5 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.4 6.0 GO:0005641 nuclear envelope lumen(GO:0005641)
0.4 2.5 GO:0001740 Barr body(GO:0001740)
0.3 2.7 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.3 1.3 GO:0097512 cardiac myofibril(GO:0097512)
0.3 2.8 GO:0097427 microtubule bundle(GO:0097427)
0.3 2.1 GO:0031527 filopodium membrane(GO:0031527)
0.3 1.8 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.3 0.8 GO:0031251 PAN complex(GO:0031251)
0.2 7.4 GO:0097228 sperm principal piece(GO:0097228)
0.2 0.7 GO:0034774 secretory granule lumen(GO:0034774) cytoplasmic vesicle lumen(GO:0060205)
0.2 13.8 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.2 7.3 GO:0034451 centriolar satellite(GO:0034451)
0.2 6.2 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.2 3.5 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.2 2.7 GO:0097542 ciliary tip(GO:0097542)
0.2 1.1 GO:0005955 calcineurin complex(GO:0005955)
0.2 0.7 GO:1990761 growth cone lamellipodium(GO:1990761)
0.2 0.7 GO:0044302 dentate gyrus mossy fiber(GO:0044302)
0.2 8.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.2 21.6 GO:0017053 transcriptional repressor complex(GO:0017053)
0.2 3.4 GO:0099634 postsynaptic specialization membrane(GO:0099634)
0.2 8.8 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 0.7 GO:1990769 proximal neuron projection(GO:1990769)
0.1 1.0 GO:0001940 male pronucleus(GO:0001940)
0.1 0.6 GO:0044194 cytolytic granule(GO:0044194) tertiary granule(GO:0070820)
0.1 1.9 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 1.6 GO:0098936 intrinsic component of postsynaptic membrane(GO:0098936) integral component of postsynaptic membrane(GO:0099055) intrinsic component of synaptic membrane(GO:0099240) integral component of synaptic membrane(GO:0099699)
0.1 5.0 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 0.4 GO:0120001 apical plasma membrane urothelial plaque(GO:0120001)
0.1 7.7 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 0.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 3.9 GO:0097440 apical dendrite(GO:0097440)
0.1 11.5 GO:0031674 I band(GO:0031674)
0.1 1.5 GO:0001527 microfibril(GO:0001527)
0.1 6.1 GO:0031985 Golgi cisterna(GO:0031985)
0.1 1.8 GO:0030017 sarcomere(GO:0030017)
0.1 1.0 GO:0036501 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) UFD1-NPL4 complex(GO:0036501)
0.1 0.3 GO:0071203 WASH complex(GO:0071203)
0.1 3.8 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.1 0.9 GO:0031209 SCAR complex(GO:0031209)
0.1 0.9 GO:0032009 early phagosome(GO:0032009)
0.1 1.7 GO:0005795 Golgi stack(GO:0005795)
0.1 1.8 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 2.6 GO:0045335 phagocytic vesicle(GO:0045335)
0.1 3.2 GO:0005871 kinesin complex(GO:0005871)
0.1 2.3 GO:0016459 myosin complex(GO:0016459)
0.1 16.4 GO:0014069 postsynaptic density(GO:0014069) asymmetric synapse(GO:0032279) postsynaptic specialization(GO:0099572)
0.0 13.8 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.2 GO:1990032 parallel fiber(GO:1990032)
0.0 1.4 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 1.2 GO:0001533 cornified envelope(GO:0001533)
0.0 0.3 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.9 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 0.4 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.3 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 1.2 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 1.0 GO:0031941 filamentous actin(GO:0031941)
0.0 2.2 GO:0030139 endocytic vesicle(GO:0030139)
0.0 0.5 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.7 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 5.1 GO:0000139 Golgi membrane(GO:0000139)
0.0 1.7 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 2.8 GO:0030427 site of polarized growth(GO:0030427)
0.0 4.0 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 1.0 GO:0042629 mast cell granule(GO:0042629)
0.0 0.4 GO:0000346 transcription export complex(GO:0000346)
0.0 2.0 GO:0030027 lamellipodium(GO:0030027)
0.0 0.4 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.8 GO:0042641 actomyosin(GO:0042641)
0.0 1.1 GO:0000786 nucleosome(GO:0000786)
0.0 1.9 GO:0000776 kinetochore(GO:0000776)
0.0 0.9 GO:0001650 fibrillar center(GO:0001650)
0.0 0.3 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.2 GO:0000421 autophagosome membrane(GO:0000421)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
7.0 70.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
1.6 16.0 GO:0031014 troponin T binding(GO:0031014)
1.4 5.5 GO:0031708 endothelin B receptor binding(GO:0031708)
1.3 12.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
1.3 13.2 GO:0004498 calcidiol 1-monooxygenase activity(GO:0004498)
1.2 18.4 GO:0005523 tropomyosin binding(GO:0005523)
1.1 6.8 GO:0004111 creatine kinase activity(GO:0004111)
1.1 6.4 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
1.0 6.0 GO:1902944 aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902944)
0.9 2.8 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.9 4.3 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.8 4.9 GO:0004126 cytidine deaminase activity(GO:0004126)
0.8 2.4 GO:0048030 disaccharide binding(GO:0048030)
0.7 9.7 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.7 2.8 GO:0004092 carnitine O-acetyltransferase activity(GO:0004092)
0.7 7.4 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.6 3.2 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.6 1.9 GO:0023030 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.6 2.5 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.6 8.5 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.6 2.9 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.6 3.9 GO:0004687 myosin light chain kinase activity(GO:0004687) myosin light chain binding(GO:0032027)
0.5 2.7 GO:0035184 histone threonine kinase activity(GO:0035184)
0.5 5.3 GO:0043559 insulin binding(GO:0043559)
0.5 5.8 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.5 2.0 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
0.5 27.3 GO:0008307 structural constituent of muscle(GO:0008307)
0.5 2.0 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.5 2.5 GO:0038100 nodal binding(GO:0038100)
0.5 4.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.5 4.2 GO:0061133 endopeptidase activator activity(GO:0061133)
0.4 1.2 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.4 3.6 GO:0034711 inhibin binding(GO:0034711)
0.4 4.4 GO:0042609 CD4 receptor binding(GO:0042609)
0.4 4.8 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.4 8.7 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.4 9.8 GO:0030506 ankyrin binding(GO:0030506)
0.4 1.9 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.4 11.0 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.4 2.8 GO:0005344 oxygen transporter activity(GO:0005344)
0.3 4.2 GO:0005522 profilin binding(GO:0005522)
0.3 11.2 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.3 5.3 GO:0043495 protein membrane anchor(GO:0043495)
0.3 2.5 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.3 4.3 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.3 3.6 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.3 5.0 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.3 1.2 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.3 0.9 GO:0052743 inositol tetrakisphosphate phosphatase activity(GO:0052743)
0.3 1.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.3 1.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.3 1.6 GO:0004359 glutaminase activity(GO:0004359)
0.3 1.1 GO:0051373 telethonin binding(GO:0031433) FATZ binding(GO:0051373)
0.3 1.8 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.2 1.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.2 2.2 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.2 8.7 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.2 12.9 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.2 1.3 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.2 0.7 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.2 9.0 GO:0003785 actin monomer binding(GO:0003785)
0.2 5.3 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.2 1.1 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.2 0.8 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
0.2 1.0 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.2 1.7 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.2 1.7 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.2 1.1 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.2 3.6 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.2 1.5 GO:0038132 neuregulin binding(GO:0038132)
0.2 1.0 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.2 1.0 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.2 1.0 GO:0061649 ubiquitin modification-dependent histone binding(GO:0061649)
0.2 1.6 GO:0008527 taste receptor activity(GO:0008527)
0.2 3.2 GO:0051861 glycolipid binding(GO:0051861)
0.2 2.7 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1 3.3 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.1 3.5 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 0.9 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.1 5.2 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.1 1.8 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907) G-protein coupled neurotransmitter receptor activity(GO:0099528)
0.1 3.6 GO:0003774 motor activity(GO:0003774)
0.1 4.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 3.4 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 1.0 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 1.2 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.1 1.8 GO:0003680 AT DNA binding(GO:0003680)
0.1 4.2 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.8 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 5.4 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 0.5 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 2.1 GO:0001618 virus receptor activity(GO:0001618)
0.1 3.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 3.0 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 3.0 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 4.0 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 12.0 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1 4.4 GO:0045182 translation regulator activity(GO:0045182)
0.1 3.8 GO:0005158 insulin receptor binding(GO:0005158)
0.1 3.6 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 3.8 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 0.7 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.1 2.6 GO:0031490 chromatin DNA binding(GO:0031490)
0.1 1.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 2.5 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 0.3 GO:2001069 glycogen binding(GO:2001069)
0.1 0.1 GO:0016015 morphogen activity(GO:0016015)
0.1 2.5 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 1.5 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 0.6 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 6.6 GO:0005178 integrin binding(GO:0005178)
0.0 0.8 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.5 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.0 0.8 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 3.3 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.7 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0 11.6 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.4 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 4.1 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.4 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.1 GO:0099103 channel activator activity(GO:0099103) potassium channel activator activity(GO:0099104)
0.0 1.1 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 1.7 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 3.2 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 2.6 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.3 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 1.7 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.4 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 2.3 GO:0005179 hormone activity(GO:0005179)
0.0 1.8 GO:0003720 telomerase activity(GO:0003720)
0.0 3.3 GO:0001076 transcription factor activity, RNA polymerase II transcription factor binding(GO:0001076)
0.0 0.7 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.9 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.4 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.5 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.8 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 1.3 GO:0004536 deoxyribonuclease activity(GO:0004536)
0.0 0.4 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.4 GO:0002039 p53 binding(GO:0002039)
0.0 0.7 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 3.7 GO:0005096 GTPase activator activity(GO:0005096)
0.0 1.7 GO:0001664 G-protein coupled receptor binding(GO:0001664)
0.0 0.5 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.7 GO:0017022 myosin binding(GO:0017022)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 6.5 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.2 19.3 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.2 14.0 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.2 3.2 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.2 5.8 PID_IGF1_PATHWAY IGF1 pathway
0.2 4.3 PID_PI3K_PLC_TRK_PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.2 5.5 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.2 6.4 PID_MAPK_TRK_PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.1 12.0 PID_ERBB1_DOWNSTREAM_PATHWAY ErbB1 downstream signaling
0.1 6.8 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.1 0.8 SA_FAS_SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 4.7 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.1 5.4 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.1 5.5 PID_RB_1PATHWAY Regulation of retinoblastoma protein
0.1 1.7 PID_S1P_S1P1_PATHWAY S1P1 pathway
0.1 2.2 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.1 1.0 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.1 5.3 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.1 1.5 PID_EPO_PATHWAY EPO signaling pathway
0.1 6.4 PID_NOTCH_PATHWAY Notch signaling pathway
0.1 1.1 PID_TNF_PATHWAY TNF receptor signaling pathway
0.1 1.5 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 1.9 PID_A6B1_A6B4_INTEGRIN_PATHWAY a6b1 and a6b4 Integrin signaling
0.1 3.6 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 1.1 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.1 1.5 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 5.6 PID_P53_DOWNSTREAM_PATHWAY Direct p53 effectors
0.0 3.6 PID_CMYB_PATHWAY C-MYB transcription factor network
0.0 0.9 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.6 PID_RETINOIC_ACID_PATHWAY Retinoic acid receptors-mediated signaling
0.0 1.7 PID_P53_REGULATION_PATHWAY p53 pathway
0.0 5.4 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.7 ST_GRANULE_CELL_SURVIVAL_PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 1.0 PID_TELOMERASE_PATHWAY Regulation of Telomerase
0.0 1.1 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.3 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.6 PID_CDC42_PATHWAY CDC42 signaling events
0.0 0.7 PID_AURORA_B_PATHWAY Aurora B signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 79.1 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
1.1 56.4 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.6 12.1 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.5 11.2 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.5 6.4 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.4 4.6 REACTOME_TRANSPORT_OF_ORGANIC_ANIONS Genes involved in Transport of organic anions
0.4 3.6 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.4 4.8 REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.3 17.5 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.3 13.8 REACTOME_G1_PHASE Genes involved in G1 Phase
0.3 10.2 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.2 5.6 REACTOME_ERK_MAPK_TARGETS Genes involved in ERK/MAPK targets
0.2 4.5 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.2 8.3 REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS Genes involved in Trafficking of AMPA receptors
0.2 2.3 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 2.0 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 2.2 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.1 4.2 REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 2.3 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 6.1 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 4.3 REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 1.5 REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.1 1.8 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 2.8 REACTOME_PEROXISOMAL_LIPID_METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 4.2 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.1 2.8 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.1 1.2 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 2.2 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.1 1.7 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 2.5 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 1.6 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 1.1 REACTOME_TRAF6_MEDIATED_NFKB_ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.1 1.6 REACTOME_THE_ROLE_OF_NEF_IN_HIV1_REPLICATION_AND_DISEASE_PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1 2.4 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 1.5 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 2.2 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.9 REACTOME_RNA_POL_III_CHAIN_ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.8 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 8.8 REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 4.7 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.9 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 1.6 REACTOME_G_ALPHA_S_SIGNALLING_EVENTS Genes involved in G alpha (s) signalling events
0.0 3.7 REACTOME_G_ALPHA_I_SIGNALLING_EVENTS Genes involved in G alpha (i) signalling events
0.0 1.0 REACTOME_ENOS_ACTIVATION_AND_REGULATION Genes involved in eNOS activation and regulation
0.0 1.4 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.9 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.0 0.7 REACTOME_ELONGATION_ARREST_AND_RECOVERY Genes involved in Elongation arrest and recovery
0.0 1.4 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.8 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.0 4.6 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.7 REACTOME_SPHINGOLIPID_METABOLISM Genes involved in Sphingolipid metabolism
0.0 0.5 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
0.0 1.9 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 5.0 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.6 REACTOME_REGULATION_OF_SIGNALING_BY_CBL Genes involved in Regulation of signaling by CBL
0.0 0.3 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 0.5 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.0 1.7 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.0 0.4 REACTOME_TRANSPORT_OF_MATURE_MRNA_DERIVED_FROM_AN_INTRONLESS_TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0 0.8 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.4 REACTOME_CHONDROITIN_SULFATE_DERMATAN_SULFATE_METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism