Motif ID: Nanog

Z-value: 1.321


Transcription factors associated with Nanog:

Gene SymbolEntrez IDGene Name
Nanog ENSMUSG00000012396.6 Nanog

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nanogmm10_v2_chr6_+_122707489_1227076080.173.2e-01Click!


Activity profile for motif Nanog.

activity profile for motif Nanog


Sorted Z-values histogram for motif Nanog

Sorted Z-values for motif Nanog



Network of associatons between targets according to the STRING database.



First level regulatory network of Nanog

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_+_41458923 10.518 ENSMUST00000031910.7
Prss1
protease, serine, 1 (trypsin 1)
chr19_-_11640828 10.494 ENSMUST00000112984.2
Ms4a3
membrane-spanning 4-domains, subfamily A, member 3
chr6_+_41392356 8.619 ENSMUST00000049079.7
Gm5771
predicted gene 5771
chr7_-_142679533 7.476 ENSMUST00000162317.1
ENSMUST00000125933.1
ENSMUST00000105931.1
ENSMUST00000105930.1
ENSMUST00000105933.1
ENSMUST00000105932.1
ENSMUST00000000220.2
Ins2






insulin II






chr2_+_128591205 7.065 ENSMUST00000155430.1
Gm355
predicted gene 355
chr17_+_29135056 7.056 ENSMUST00000087942.4
Rab44
RAB44, member RAS oncogene family
chr9_+_65890237 6.425 ENSMUST00000045802.6
2810417H13Rik
RIKEN cDNA 2810417H13 gene
chr6_+_41354105 6.058 ENSMUST00000072103.5
Try10
trypsin 10
chr17_+_40811089 5.574 ENSMUST00000024721.7
Rhag
Rhesus blood group-associated A glycoprotein
chr1_-_75133866 5.539 ENSMUST00000027405.4
Slc23a3
solute carrier family 23 (nucleobase transporters), member 3
chr14_+_27000362 5.241 ENSMUST00000035433.8
Hesx1
homeobox gene expressed in ES cells
chr12_+_109549157 5.208 ENSMUST00000128458.1
ENSMUST00000150851.1
Meg3

maternally expressed 3

chr9_-_123678782 4.936 ENSMUST00000170591.1
ENSMUST00000171647.1
Slc6a20a

solute carrier family 6 (neurotransmitter transporter), member 20A

chrX_+_8271133 4.890 ENSMUST00000127103.1
ENSMUST00000115591.1
Slc38a5

solute carrier family 38, member 5

chr2_+_164948219 4.865 ENSMUST00000017881.2
Mmp9
matrix metallopeptidase 9
chrX_+_8271381 4.747 ENSMUST00000033512.4
Slc38a5
solute carrier family 38, member 5
chr7_-_6730412 4.725 ENSMUST00000051209.4
Peg3
paternally expressed 3
chr18_+_36528145 4.678 ENSMUST00000074298.6
ENSMUST00000115694.2
Slc4a9

solute carrier family 4, sodium bicarbonate cotransporter, member 9

chr3_+_105870858 4.406 ENSMUST00000164730.1
Adora3
adenosine A3 receptor
chr6_+_41302265 4.173 ENSMUST00000031913.4
Try4
trypsin 4
chr5_+_33658123 3.997 ENSMUST00000074849.6
ENSMUST00000079534.4
Tacc3

transforming, acidic coiled-coil containing protein 3

chrX_+_8271642 3.828 ENSMUST00000115590.1
Slc38a5
solute carrier family 38, member 5
chr9_-_123678873 3.644 ENSMUST00000040960.6
Slc6a20a
solute carrier family 6 (neurotransmitter transporter), member 20A
chr3_+_114030532 3.582 ENSMUST00000123619.1
ENSMUST00000092155.5
Col11a1

collagen, type XI, alpha 1

chr10_+_58394361 3.546 ENSMUST00000020077.4
Lims1
LIM and senescent cell antigen-like domains 1
chr7_+_79660196 3.479 ENSMUST00000035977.7
Ticrr
TOPBP1-interacting checkpoint and replication regulator
chr12_-_69790660 3.391 ENSMUST00000021377.4
Cdkl1
cyclin-dependent kinase-like 1 (CDC2-related kinase)
chr16_-_18622403 3.377 ENSMUST00000167388.1
Gp1bb
glycoprotein Ib, beta polypeptide
chr15_+_80097866 3.369 ENSMUST00000143928.1
Syngr1
synaptogyrin 1
chr5_+_33658567 3.360 ENSMUST00000114426.3
Tacc3
transforming, acidic coiled-coil containing protein 3
chr3_-_54915867 3.333 ENSMUST00000070342.3
Sertm1
serine rich and transmembrane domain containing 1
chr3_+_88081997 3.324 ENSMUST00000071812.5
Iqgap3
IQ motif containing GTPase activating protein 3
chr5_+_33658550 3.322 ENSMUST00000152847.1
Tacc3
transforming, acidic coiled-coil containing protein 3
chr15_-_103251465 3.233 ENSMUST00000133600.1
ENSMUST00000134554.1
ENSMUST00000156927.1
ENSMUST00000149111.1
ENSMUST00000132836.1
Nfe2




nuclear factor, erythroid derived 2




chr10_+_58394381 3.233 ENSMUST00000105468.1
Lims1
LIM and senescent cell antigen-like domains 1
chr3_+_105870898 3.086 ENSMUST00000010279.5
Adora3
adenosine A3 receptor
chr7_-_14254870 2.965 ENSMUST00000184731.1
ENSMUST00000076576.6
Sult2a6

sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 6

chr19_-_9899450 2.939 ENSMUST00000025562.7
Incenp
inner centromere protein
chr7_-_14123042 2.824 ENSMUST00000098809.2
Sult2a3
sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 3
chr4_-_49597425 2.733 ENSMUST00000150664.1
Tmem246
transmembrane protein 246
chr9_-_20959785 2.709 ENSMUST00000177754.1
Dnmt1
DNA methyltransferase (cytosine-5) 1
chr3_+_68869563 2.698 ENSMUST00000054551.2
1110032F04Rik
RIKEN cDNA 1110032F04 gene
chrX_+_134308084 2.665 ENSMUST00000081064.5
ENSMUST00000101251.1
ENSMUST00000129782.1
Cenpi


centromere protein I


chr11_+_44617310 2.549 ENSMUST00000081265.5
ENSMUST00000101326.3
ENSMUST00000109268.1
Ebf1


early B cell factor 1


chr11_+_62248977 2.536 ENSMUST00000018644.2
Adora2b
adenosine A2b receptor
chr6_+_124829582 2.454 ENSMUST00000024270.7
Cdca3
cell division cycle associated 3
chr12_+_102128718 2.402 ENSMUST00000159329.1
Slc24a4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr15_+_44457522 2.398 ENSMUST00000166957.1
ENSMUST00000038336.5
Pkhd1l1

polycystic kidney and hepatic disease 1-like 1

chr7_+_19411086 2.392 ENSMUST00000003643.1
Ckm
creatine kinase, muscle
chr6_-_136781718 2.372 ENSMUST00000078095.6
ENSMUST00000032338.7
Gucy2c

guanylate cyclase 2c

chr18_-_21652362 2.324 ENSMUST00000049105.4
Klhl14
kelch-like 14
chr12_+_109747903 2.312 ENSMUST00000183084.1
ENSMUST00000182300.1
Mirg

miRNA containing gene

chr6_-_145047725 2.251 ENSMUST00000123930.1
Bcat1
branched chain aminotransferase 1, cytosolic
chr6_-_67037399 2.244 ENSMUST00000043098.6
Gadd45a
growth arrest and DNA-damage-inducible 45 alpha
chr2_-_116067391 2.233 ENSMUST00000140185.1
2700033N17Rik
RIKEN cDNA 2700033N17 gene
chr7_-_100467149 2.202 ENSMUST00000184420.1
RP23-308M1.2
RP23-308M1.2
chr15_-_66831625 2.194 ENSMUST00000164163.1
Sla
src-like adaptor
chr7_-_133702515 2.187 ENSMUST00000153698.1
Uros
uroporphyrinogen III synthase
chr3_+_122044428 2.161 ENSMUST00000013995.8
Abca4
ATP-binding cassette, sub-family A (ABC1), member 4
chr6_+_124829540 2.122 ENSMUST00000150120.1
Cdca3
cell division cycle associated 3
chrX_-_164250368 2.117 ENSMUST00000112263.1
Bmx
BMX non-receptor tyrosine kinase
chr11_-_116077606 2.115 ENSMUST00000106450.1
Unc13d
unc-13 homolog D (C. elegans)
chr3_-_144760841 2.101 ENSMUST00000059091.5
Clca1
chloride channel calcium activated 1
chr17_-_25727364 2.084 ENSMUST00000170070.1
ENSMUST00000048054.7
Chtf18

CTF18, chromosome transmission fidelity factor 18

chr13_-_89742244 2.067 ENSMUST00000109543.2
ENSMUST00000159337.1
ENSMUST00000159910.1
ENSMUST00000109544.2
Vcan



versican



chr12_-_91384403 2.057 ENSMUST00000141429.1
Cep128
centrosomal protein 128
chr3_+_37312514 2.032 ENSMUST00000057975.7
ENSMUST00000108121.3
Bbs12

Bardet-Biedl syndrome 12 (human)

chr4_+_154960915 2.015 ENSMUST00000049621.6
Hes5
hairy and enhancer of split 5 (Drosophila)
chr15_-_51991679 2.006 ENSMUST00000022927.9
Rad21
RAD21 homolog (S. pombe)
chr3_-_116253467 1.989 ENSMUST00000090473.5
Gpr88
G-protein coupled receptor 88
chr18_+_82554463 1.901 ENSMUST00000062446.7
ENSMUST00000102812.4
ENSMUST00000075372.5
ENSMUST00000080658.4
ENSMUST00000152071.1
ENSMUST00000114674.3
ENSMUST00000142850.1
ENSMUST00000133193.1
ENSMUST00000123251.1
ENSMUST00000153478.1
ENSMUST00000132369.1
Mbp










myelin basic protein










chr10_+_130322845 1.867 ENSMUST00000042586.8
Tespa1
thymocyte expressed, positive selection associated 1
chr17_-_81649607 1.864 ENSMUST00000163680.2
ENSMUST00000086538.3
ENSMUST00000163123.1
Slc8a1


solute carrier family 8 (sodium/calcium exchanger), member 1


chr6_-_102464667 1.856 ENSMUST00000032159.6
Cntn3
contactin 3
chr11_+_115154139 1.827 ENSMUST00000021076.5
Rab37
RAB37, member of RAS oncogene family
chr3_+_105904377 1.814 ENSMUST00000000574.1
Adora3
adenosine A3 receptor
chr9_-_15357692 1.799 ENSMUST00000098979.3
ENSMUST00000161132.1
5830418K08Rik

RIKEN cDNA 5830418K08 gene

chr7_-_115846080 1.756 ENSMUST00000166207.1
Sox6
SRY-box containing gene 6
chr15_+_9436028 1.743 ENSMUST00000042360.3
Capsl
calcyphosine-like
chr3_-_107239707 1.664 ENSMUST00000049852.8
Prok1
prokineticin 1
chr6_-_50456085 1.642 ENSMUST00000146341.1
ENSMUST00000071728.4
Osbpl3

oxysterol binding protein-like 3

chr13_-_19732929 1.597 ENSMUST00000151029.1
A530099J19Rik
RIKEN cDNA A530099J19 gene
chr6_-_136922169 1.555 ENSMUST00000032343.6
Erp27
endoplasmic reticulum protein 27
chr13_-_89742490 1.550 ENSMUST00000109546.2
Vcan
versican
chr12_-_83487708 1.541 ENSMUST00000177959.1
ENSMUST00000178756.1
Dpf3

D4, zinc and double PHD fingers, family 3

chr11_+_62820469 1.540 ENSMUST00000108703.1
Trim16
tripartite motif-containing 16
chr7_+_43437073 1.531 ENSMUST00000070518.2
Nkg7
natural killer cell group 7 sequence
chr17_-_51826562 1.510 ENSMUST00000024720.4
ENSMUST00000129667.1
ENSMUST00000156051.1
ENSMUST00000169480.1
ENSMUST00000148559.1
Satb1




special AT-rich sequence binding protein 1




chr4_+_12906838 1.508 ENSMUST00000143186.1
ENSMUST00000183345.1
Triqk

triple QxxK/R motif containing

chrX_+_48146436 1.490 ENSMUST00000033427.6
Sash3
SAM and SH3 domain containing 3
chr4_+_126024506 1.461 ENSMUST00000106162.1
Csf3r
colony stimulating factor 3 receptor (granulocyte)
chr14_-_49245389 1.445 ENSMUST00000130853.1
ENSMUST00000022398.7
1700011H14Rik

RIKEN cDNA 1700011H14 gene

chr17_-_47834682 1.435 ENSMUST00000066368.6
Mdfi
MyoD family inhibitor
chr5_-_138172383 1.401 ENSMUST00000000505.9
Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chrX_+_49470450 1.394 ENSMUST00000114904.3
Arhgap36
Rho GTPase activating protein 36
chr13_+_44729794 1.385 ENSMUST00000172830.1
Jarid2
jumonji, AT rich interactive domain 2
chr16_+_44765732 1.380 ENSMUST00000057488.8
Cd200r1
CD200 receptor 1
chr4_+_43506966 1.377 ENSMUST00000030183.3
Car9
carbonic anhydrase 9
chr7_+_28693032 1.360 ENSMUST00000151227.1
ENSMUST00000108281.1
Fbxo27

F-box protein 27

chr1_-_87101590 1.356 ENSMUST00000113270.2
Alpi
alkaline phosphatase, intestinal
chr16_+_19760902 1.351 ENSMUST00000119468.1
B3gnt5
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr12_+_69790288 1.340 ENSMUST00000021378.3
4930512B01Rik
RIKEN cDNA 4930512B01 gene
chr7_-_141655319 1.332 ENSMUST00000062451.7
Muc6
mucin 6, gastric
chr3_+_103860265 1.329 ENSMUST00000029433.7
Ptpn22
protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
chr6_-_145047636 1.327 ENSMUST00000149769.1
Bcat1
branched chain aminotransferase 1, cytosolic
chrX_+_49470555 1.305 ENSMUST00000042444.6
Arhgap36
Rho GTPase activating protein 36
chr4_+_101507947 1.305 ENSMUST00000149047.1
ENSMUST00000106929.3
Dnajc6

DnaJ (Hsp40) homolog, subfamily C, member 6

chr17_-_43543639 1.297 ENSMUST00000178772.1
Ankrd66
ankyrin repeat domain 66
chr6_+_125552948 1.295 ENSMUST00000112254.1
ENSMUST00000112253.1
ENSMUST00000001995.7
Vwf


Von Willebrand factor homolog


chr13_-_47106176 1.294 ENSMUST00000021807.6
ENSMUST00000135278.1
Dek

DEK oncogene (DNA binding)

chr17_+_35841668 1.276 ENSMUST00000174124.1
Mdc1
mediator of DNA damage checkpoint 1
chr18_+_35553401 1.264 ENSMUST00000181664.1
Snhg4
small nucleolar RNA host gene 4 (non-protein coding)
chr3_-_37312418 1.262 ENSMUST00000075537.6
ENSMUST00000071400.6
ENSMUST00000102955.4
ENSMUST00000140956.1
Cetn4



centrin 4



chr2_+_57997884 1.256 ENSMUST00000112616.1
ENSMUST00000166729.1
Galnt5

UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5

chr13_-_12258093 1.252 ENSMUST00000099856.4
Mtr
5-methyltetrahydrofolate-homocysteine methyltransferase
chr7_-_45694369 1.250 ENSMUST00000040636.6
Sec1
secretory blood group 1
chr4_-_149454971 1.245 ENSMUST00000030848.2
Rbp7
retinol binding protein 7, cellular
chr11_-_20332689 1.236 ENSMUST00000109594.1
Slc1a4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr5_+_25246775 1.233 ENSMUST00000144971.1
Galnt11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11
chr18_-_15063560 1.228 ENSMUST00000168989.1
Kctd1
potassium channel tetramerisation domain containing 1
chr3_-_49757257 1.217 ENSMUST00000035931.7
Pcdh18
protocadherin 18
chr15_-_93519499 1.202 ENSMUST00000109255.2
Prickle1
prickle homolog 1 (Drosophila)
chr11_-_20332654 1.195 ENSMUST00000004634.6
Slc1a4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr5_+_30711849 1.179 ENSMUST00000088081.4
ENSMUST00000101442.3
Dpysl5

dihydropyrimidinase-like 5

chr6_+_125145235 1.167 ENSMUST00000119527.1
ENSMUST00000088276.6
ENSMUST00000051171.7
ENSMUST00000117675.1
Iffo1



intermediate filament family orphan 1



chr2_-_45112890 1.141 ENSMUST00000076836.6
Zeb2
zinc finger E-box binding homeobox 2
chr13_-_51567084 1.134 ENSMUST00000021898.5
Shc3
src homology 2 domain-containing transforming protein C3
chr2_+_125152505 1.129 ENSMUST00000110494.2
ENSMUST00000028630.2
ENSMUST00000110495.2
Slc12a1


solute carrier family 12, member 1


chr3_-_144819494 1.117 ENSMUST00000029929.7
Clca2
chloride channel calcium activated 2
chr17_+_8849974 1.105 ENSMUST00000115720.1
Pde10a
phosphodiesterase 10A
chr19_+_8802486 1.089 ENSMUST00000172175.1
Zbtb3
zinc finger and BTB domain containing 3
chr4_-_43046196 1.080 ENSMUST00000036462.5
Fam214b
family with sequence similarity 214, member B
chr13_-_19619820 1.079 ENSMUST00000002885.6
Epdr1
ependymin related protein 1 (zebrafish)
chr3_+_79884576 1.076 ENSMUST00000145992.1
Fam198b
family with sequence similarity 198, member B
chr5_-_16731074 1.071 ENSMUST00000073014.5
Gm8991
predicted pseudogene 8991
chr10_-_127351753 1.069 ENSMUST00000059718.4
Inhbe
inhibin beta E
chr3_+_10088173 1.046 ENSMUST00000061419.7
Gm9833
predicted gene 9833
chrX_+_159840463 1.041 ENSMUST00000112451.1
ENSMUST00000112453.2
Sh3kbp1

SH3-domain kinase binding protein 1

chr11_-_101095367 1.037 ENSMUST00000019447.8
Psmc3ip
proteasome (prosome, macropain) 26S subunit, ATPase 3, interacting protein
chr1_+_172555932 1.033 ENSMUST00000061835.3
Vsig8
V-set and immunoglobulin domain containing 8
chr12_+_72441852 1.029 ENSMUST00000162159.1
Lrrc9
leucine rich repeat containing 9
chr7_+_25267669 1.014 ENSMUST00000169266.1
Cic
capicua homolog (Drosophila)
chr19_-_32196393 0.976 ENSMUST00000151822.1
Sgms1
sphingomyelin synthase 1
chr2_+_130274437 0.968 ENSMUST00000141872.1
Nop56
NOP56 ribonucleoprotein
chr17_+_78491549 0.961 ENSMUST00000079363.4
Gm10093
predicted pseudogene 10093
chr10_+_33905015 0.960 ENSMUST00000169670.1
Rsph4a
radial spoke head 4 homolog A (Chlamydomonas)
chr4_-_83052229 0.954 ENSMUST00000107230.1
Frem1
Fras1 related extracellular matrix protein 1
chr9_-_44342332 0.939 ENSMUST00000097558.3
Hmbs
hydroxymethylbilane synthase
chr14_-_18270953 0.934 ENSMUST00000100799.2
ENSMUST00000079419.4
ENSMUST00000080281.7
Rpl15


ribosomal protein L15


chr3_-_82876483 0.933 ENSMUST00000048647.7
Rbm46
RNA binding motif protein 46
chr6_-_116716888 0.925 ENSMUST00000056623.6
Tmem72
transmembrane protein 72
chrX_+_7822289 0.925 ENSMUST00000009875.4
Kcnd1
potassium voltage-gated channel, Shal-related family, member 1
chr8_+_110721462 0.913 ENSMUST00000052457.8
Mtss1l
metastasis suppressor 1-like
chr11_-_98053415 0.912 ENSMUST00000017544.2
Stac2
SH3 and cysteine rich domain 2
chr15_-_13173607 0.911 ENSMUST00000036439.4
Cdh6
cadherin 6
chr7_-_116084635 0.911 ENSMUST00000111755.3
Gm4353
predicted gene 4353
chr15_-_34356421 0.899 ENSMUST00000179647.1
9430069I07Rik
RIKEN cDNA 9430069I07 gene
chr3_+_65666223 0.892 ENSMUST00000099075.2
ENSMUST00000107848.1
ENSMUST00000161794.1
Lekr1


leucine, glutamate and lysine rich 1


chr2_+_127909058 0.890 ENSMUST00000110344.1
Acoxl
acyl-Coenzyme A oxidase-like
chr18_+_37518341 0.887 ENSMUST00000097609.1
Pcdhb22
protocadherin beta 22
chr5_-_99978914 0.886 ENSMUST00000112939.3
ENSMUST00000171786.1
ENSMUST00000072750.6
ENSMUST00000019128.8
ENSMUST00000172361.1
Hnrnpd




heterogeneous nuclear ribonucleoprotein D




chr4_+_101507855 0.867 ENSMUST00000038207.5
Dnajc6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr1_-_172027251 0.855 ENSMUST00000138714.1
Vangl2
vang-like 2 (van gogh, Drosophila)
chr17_+_7170101 0.851 ENSMUST00000024575.6
Rps6ka2
ribosomal protein S6 kinase, polypeptide 2
chr6_-_142473075 0.848 ENSMUST00000032371.7
Gys2
glycogen synthase 2
chr3_-_55055038 0.837 ENSMUST00000029368.2
Ccna1
cyclin A1
chr7_+_113514085 0.812 ENSMUST00000122890.1
Far1
fatty acyl CoA reductase 1
chr16_+_20696175 0.800 ENSMUST00000128273.1
Fam131a
family with sequence similarity 131, member A
chr7_+_128246953 0.790 ENSMUST00000167965.1
Tgfb1i1
transforming growth factor beta 1 induced transcript 1
chr9_+_106368594 0.786 ENSMUST00000172306.2
Dusp7
dual specificity phosphatase 7
chr4_+_48585193 0.786 ENSMUST00000107703.1
Tmeff1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr11_-_40733373 0.777 ENSMUST00000020579.8
Hmmr
hyaluronan mediated motility receptor (RHAMM)
chr7_+_112742025 0.770 ENSMUST00000164363.1
Tead1
TEA domain family member 1
chr6_+_71909046 0.763 ENSMUST00000055296.8
Polr1a
polymerase (RNA) I polypeptide A
chr10_-_61476937 0.760 ENSMUST00000051330.4
D830039M14Rik
RIKEN cDNA D830039M14 gene
chr6_-_29179584 0.758 ENSMUST00000159200.1
Prrt4
proline-rich transmembrane protein 4
chr8_-_120589304 0.758 ENSMUST00000034278.5
Gins2
GINS complex subunit 2 (Psf2 homolog)
chr3_+_54481429 0.748 ENSMUST00000091130.3
Gm5641
predicted gene 5641
chr11_-_99244058 0.734 ENSMUST00000103132.3
ENSMUST00000038214.6
Krt222

keratin 222

chr13_+_23752267 0.721 ENSMUST00000091703.2
Hist1h3b
histone cluster 1, H3b
chr10_+_62252325 0.716 ENSMUST00000020278.5
Tacr2
tachykinin receptor 2
chr12_+_72441933 0.713 ENSMUST00000161284.1
Lrrc9
leucine rich repeat containing 9
chr7_-_110769345 0.710 ENSMUST00000098108.2
B430319F04Rik
RIKEN cDNA B430319F04 gene
chrX_-_56822308 0.706 ENSMUST00000135542.1
ENSMUST00000114766.1
Mtap7d3

MAP7 domain containing 3

chr1_+_89454769 0.694 ENSMUST00000027521.8
ENSMUST00000074945.5
Agap1

ArfGAP with GTPase domain, ankyrin repeat and PH domain 1

chr10_-_62422427 0.677 ENSMUST00000020277.8
Hkdc1
hexokinase domain containing 1
chr6_-_124779686 0.668 ENSMUST00000147669.1
ENSMUST00000128697.1
ENSMUST00000032218.3
ENSMUST00000112475.2
Lrrc23



leucine rich repeat containing 23



chr13_+_111686303 0.668 ENSMUST00000047412.4
ENSMUST00000109271.2
Mier3

mesoderm induction early response 1, family member 3

chrX_+_169879596 0.637 ENSMUST00000112105.1
ENSMUST00000078947.5
Mid1

midline 1

chr4_+_109415631 0.636 ENSMUST00000106618.1
Ttc39a
tetratricopeptide repeat domain 39A
chr2_+_112379204 0.628 ENSMUST00000028552.3
Katnbl1
katanin p80 subunit B like 1
chr4_-_11386757 0.625 ENSMUST00000108313.1
ENSMUST00000108311.2
Esrp1

epithelial splicing regulatory protein 1

chr3_-_63851251 0.624 ENSMUST00000162269.2
ENSMUST00000159676.2
ENSMUST00000175947.1
Plch1


phospholipase C, eta 1


chr3_+_37348645 0.615 ENSMUST00000038885.3
Fgf2
fibroblast growth factor 2
chr12_+_3891728 0.615 ENSMUST00000172689.1
ENSMUST00000111186.1
Dnmt3a

DNA methyltransferase 3A

chr7_-_105574324 0.610 ENSMUST00000081165.7
Apbb1
amyloid beta (A4) precursor protein-binding, family B, member 1
chr19_+_25672408 0.608 ENSMUST00000053068.5
Dmrt2
doublesex and mab-3 related transcription factor 2
chr7_+_128246812 0.607 ENSMUST00000164710.1
ENSMUST00000070656.5
Tgfb1i1

transforming growth factor beta 1 induced transcript 1

chr1_+_135584773 0.605 ENSMUST00000067468.4
Gm4793
predicted gene 4793
chr17_-_32800938 0.604 ENSMUST00000080905.6
Zfp811
zinc finger protein 811

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 7.5 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861) neuron projection maintenance(GO:1990535)
1.6 4.9 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
1.2 22.0 GO:0015816 glycine transport(GO:0015816)
0.9 9.3 GO:0002553 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.8 6.8 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.7 0.7 GO:0033685 negative regulation of luteinizing hormone secretion(GO:0033685)
0.7 2.7 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.7 2.0 GO:2000978 auditory receptor cell fate determination(GO:0042668) negative regulation of forebrain neuron differentiation(GO:2000978)
0.6 1.9 GO:1904207 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.6 10.7 GO:0030953 astral microtubule organization(GO:0030953)
0.6 1.9 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.6 5.6 GO:0015670 carbon dioxide transport(GO:0015670)
0.6 1.2 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892)
0.6 3.6 GO:0009082 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.5 2.2 GO:0006780 uroporphyrinogen III biosynthetic process(GO:0006780)
0.5 5.2 GO:0030916 otic vesicle formation(GO:0030916)
0.5 3.6 GO:0035989 tendon development(GO:0035989)
0.5 2.0 GO:0061743 motor learning(GO:0061743)
0.5 2.4 GO:0015824 proline transport(GO:0015824) proline transmembrane transport(GO:0035524)
0.4 1.3 GO:0071613 positive regulation of toll-like receptor 9 signaling pathway(GO:0034165) granzyme B production(GO:0071613) regulation of granzyme B production(GO:0071661) positive regulation of granzyme B production(GO:0071663)
0.4 3.5 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.4 2.5 GO:0002678 positive regulation of chronic inflammatory response(GO:0002678)
0.3 2.8 GO:0061789 dense core granule priming(GO:0061789)
0.3 0.6 GO:0060128 corticotropin hormone secreting cell differentiation(GO:0060128)
0.3 0.9 GO:1905663 response to rapamycin(GO:1901355) regulation of telomerase RNA reverse transcriptase activity(GO:1905661) positive regulation of telomerase RNA reverse transcriptase activity(GO:1905663)
0.3 2.0 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.3 0.9 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.3 3.2 GO:0034242 negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.3 1.9 GO:0098735 cellular response to caffeine(GO:0071313) positive regulation of the force of heart contraction(GO:0098735)
0.2 2.1 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.2 1.1 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.2 0.6 GO:0061402 positive regulation of transcription from RNA polymerase II promoter in response to acidic pH(GO:0061402)
0.2 0.6 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
0.2 28.2 GO:0007586 digestion(GO:0007586)
0.2 1.1 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.2 1.3 GO:2001032 cell quiescence(GO:0044838) regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.2 0.5 GO:0070649 meiotic chromosome movement towards spindle pole(GO:0016344) chromosome movement towards spindle pole(GO:0051305) formin-nucleated actin cable assembly(GO:0070649) formin-nucleated actin cable organization(GO:0110009)
0.2 3.4 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.2 1.8 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.2 5.2 GO:0008340 determination of adult lifespan(GO:0008340)
0.2 1.5 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.2 2.7 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.2 2.2 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.2 1.3 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.2 0.5 GO:0071918 urea transmembrane transport(GO:0071918)
0.2 0.8 GO:1904749 regulation of protein localization to nucleolus(GO:1904749)
0.2 0.6 GO:0061055 myotome development(GO:0061055)
0.1 1.1 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.1 1.4 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 1.3 GO:0071732 cellular response to nitric oxide(GO:0071732)
0.1 0.8 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.1 0.5 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.1 0.8 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.1 2.1 GO:0001865 NK T cell differentiation(GO:0001865)
0.1 2.5 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.1 4.2 GO:0015701 bicarbonate transport(GO:0015701)
0.1 1.0 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 2.4 GO:0097186 amelogenesis(GO:0097186)
0.1 0.6 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.1 1.4 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.1 0.3 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.1 1.5 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.1 0.9 GO:0002035 brain renin-angiotensin system(GO:0002035) negative regulation of meiotic nuclear division(GO:0045835)
0.1 0.9 GO:0018065 protein-cofactor linkage(GO:0018065)
0.1 4.2 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.1 0.4 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.1 1.0 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.1 3.6 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.1 0.3 GO:0002587 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) negative regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002587)
0.1 1.5 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.3 GO:2000383 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.1 1.4 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.1 1.1 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 0.4 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361) termination of RNA polymerase I transcription(GO:0006363)
0.1 2.1 GO:0034508 centromere complex assembly(GO:0034508)
0.1 0.6 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 1.3 GO:0036065 fucosylation(GO:0036065)
0.1 0.6 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 0.8 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.1 1.2 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 0.4 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055) ribosomal small subunit export from nucleus(GO:0000056)
0.1 1.0 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.5 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 1.8 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 2.4 GO:0042398 cellular modified amino acid biosynthetic process(GO:0042398)
0.0 0.2 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.2 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 2.4 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.0 0.3 GO:0016584 nucleosome positioning(GO:0016584) positive regulation of mRNA 3'-end processing(GO:0031442)
0.0 0.4 GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629)
0.0 0.3 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 0.6 GO:0045652 regulation of megakaryocyte differentiation(GO:0045652)
0.0 0.9 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.3 GO:0031125 rRNA 3'-end processing(GO:0031125)
0.0 0.8 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.2 GO:1904667 negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.0 0.3 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.0 0.3 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.2 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.2 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.0 0.7 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 2.9 GO:0000910 cytokinesis(GO:0000910)
0.0 0.1 GO:2000195 negative regulation of female gonad development(GO:2000195)
0.0 2.9 GO:0050817 blood coagulation(GO:0007596) coagulation(GO:0050817)
0.0 0.7 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.4 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.7 GO:0001678 cellular glucose homeostasis(GO:0001678)
0.0 0.3 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 1.1 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.1 GO:1904177 regulation of adipose tissue development(GO:1904177)
0.0 0.1 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.4 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 1.2 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.5 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.0 GO:0051231 spindle elongation(GO:0051231)
0.0 0.3 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.1 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 1.2 GO:0030148 sphingolipid biosynthetic process(GO:0030148)
0.0 0.2 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.8 GO:0048286 lung alveolus development(GO:0048286)
0.0 0.2 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.0 1.0 GO:0003341 cilium movement(GO:0003341)
0.0 0.2 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 1.9 GO:0071772 response to BMP(GO:0071772) cellular response to BMP stimulus(GO:0071773)
0.0 0.1 GO:0061038 histone H3-K36 methylation(GO:0010452) uterus morphogenesis(GO:0061038)
0.0 0.3 GO:0007625 grooming behavior(GO:0007625)
0.0 0.8 GO:0001889 liver development(GO:0001889)
0.0 0.4 GO:0000154 rRNA modification(GO:0000154)
0.0 1.0 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.1 GO:0010616 negative regulation of cardiac muscle adaptation(GO:0010616)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 8.4 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.3 3.4 GO:0033093 Weibel-Palade body(GO:0033093)
0.3 2.9 GO:0000801 central element(GO:0000801)
0.3 2.0 GO:0000798 nuclear cohesin complex(GO:0000798)
0.3 3.6 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.2 1.9 GO:0033269 internode region of axon(GO:0033269)
0.2 2.1 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.2 0.9 GO:0060187 cell pole(GO:0060187)
0.2 0.8 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.2 0.5 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.2 11.3 GO:0042629 mast cell granule(GO:0042629)
0.1 2.0 GO:0042589 zymogen granule membrane(GO:0042589)
0.1 0.6 GO:1990761 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.1 0.7 GO:0044305 calyx of Held(GO:0044305)
0.1 0.8 GO:0031298 replication fork protection complex(GO:0031298)
0.1 2.0 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.1 1.0 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 2.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 2.7 GO:0005721 pericentric heterochromatin(GO:0005721)
0.1 0.4 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.1 0.4 GO:0031201 SNARE complex(GO:0031201)
0.1 0.4 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.1 1.5 GO:0071565 nBAF complex(GO:0071565)
0.1 1.6 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 1.9 GO:0031225 anchored component of membrane(GO:0031225)
0.1 1.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 4.1 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.3 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 3.0 GO:0031594 neuromuscular junction(GO:0031594)
0.0 3.2 GO:0005776 autophagosome(GO:0005776)
0.0 4.7 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.7 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.2 GO:0071010 prespliceosome(GO:0071010)
0.0 2.4 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.9 GO:0001741 XY body(GO:0001741)
0.0 1.3 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.6 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 1.3 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.3 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 1.5 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.8 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.0 0.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 1.3 GO:0042555 MCM complex(GO:0042555) MCM core complex(GO:0097373)
0.0 4.0 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.3 GO:0010369 chromocenter(GO:0010369)
0.0 0.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 6.4 GO:0005911 cell-cell junction(GO:0005911)
0.0 29.0 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 0.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.3 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 3.9 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 0.9 GO:0031672 A band(GO:0031672)
0.0 1.1 GO:0016324 apical plasma membrane(GO:0016324)
0.0 1.5 GO:0000922 spindle pole(GO:0000922)
0.0 1.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.3 GO:0036038 MKS complex(GO:0036038)
0.0 0.6 GO:0015030 Cajal body(GO:0015030)
0.0 1.1 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.8 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 2.1 GO:0000776 kinetochore(GO:0000776)
0.0 5.3 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.1 GO:0045298 tubulin complex(GO:0045298)
0.0 1.3 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.6 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.3 GO:0044430 cytoskeletal part(GO:0044430)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 13.5 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
1.1 11.8 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
1.0 11.0 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.8 5.8 GO:0004027 alcohol sulfotransferase activity(GO:0004027)
0.6 3.6 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.5 3.1 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.5 7.5 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.5 3.3 GO:0032027 myosin light chain binding(GO:0032027)
0.5 1.9 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
0.5 1.4 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.4 1.3 GO:0008107 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.4 3.3 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.4 2.4 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.4 2.4 GO:0004111 creatine kinase activity(GO:0004111)
0.4 2.2 GO:1904121 phosphatidylethanolamine transporter activity(GO:1904121)
0.3 5.6 GO:0022842 leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
0.3 0.9 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.2 0.7 GO:0004995 tachykinin receptor activity(GO:0004995)
0.2 4.7 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.2 4.9 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.2 0.9 GO:0003721 telomerase RNA reverse transcriptase activity(GO:0003721)
0.2 0.7 GO:0001565 phorbol ester receptor activity(GO:0001565) non-kinase phorbol ester receptor activity(GO:0001566)
0.2 0.6 GO:0050429 calcium-dependent phospholipase C activity(GO:0050429)
0.2 1.0 GO:0033188 ceramide phosphoethanolamine synthase activity(GO:0002950) sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.2 2.1 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.2 1.1 GO:0035827 rubidium ion transmembrane transporter activity(GO:0035827)
0.2 0.9 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.2 4.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 1.3 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.2 1.4 GO:0048495 Roundabout binding(GO:0048495)
0.2 0.8 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.2 1.1 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.1 3.2 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229) intracellular chloride channel activity(GO:0061778)
0.1 1.9 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 2.5 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.1 2.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.3 GO:0071207 histone pre-mRNA stem-loop binding(GO:0071207)
0.1 0.6 GO:0031493 nucleosomal histone binding(GO:0031493)
0.1 3.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 1.2 GO:0019841 retinal binding(GO:0016918) retinol binding(GO:0019841)
0.1 0.6 GO:0090722 receptor-receptor interaction(GO:0090722)
0.1 1.5 GO:0019966 interleukin-1 binding(GO:0019966)
0.1 1.4 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.1 1.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 0.9 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.1 1.5 GO:0005536 glucose binding(GO:0005536)
0.1 1.3 GO:0019865 immunoglobulin binding(GO:0019865)
0.1 25.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 1.3 GO:0015643 toxic substance binding(GO:0015643)
0.1 0.4 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 0.5 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1 1.0 GO:0050692 DBD domain binding(GO:0050692)
0.1 0.9 GO:0008172 S-methyltransferase activity(GO:0008172)
0.1 1.0 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 0.3 GO:0030621 U4 snRNA binding(GO:0030621)
0.1 2.8 GO:0050699 WW domain binding(GO:0050699)
0.1 0.4 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 1.2 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.1 0.8 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 3.3 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 2.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 1.4 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.1 GO:0052740 phosphatidylserine 1-acylhydrolase activity(GO:0052739) 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 0.8 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.4 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.3 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.3 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 1.3 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.3 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 3.8 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.0 0.3 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.5 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.6 GO:0048156 tau protein binding(GO:0048156)
0.0 1.6 GO:0015485 cholesterol binding(GO:0015485)
0.0 5.7 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 1.2 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.2 GO:1990948 ubiquitin ligase inhibitor activity(GO:1990948)
0.0 0.6 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.1 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.6 GO:0015026 coreceptor activity(GO:0015026)
0.0 3.0 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.9 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.2 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 1.1 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 8.4 GO:0005525 GTP binding(GO:0005525)
0.0 3.5 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.3 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 1.5 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.5 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.7 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 2.7 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.3 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.2 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.1 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 12.8 PID_AURORA_A_PATHWAY Aurora A signaling
0.3 0.8 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 8.3 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.1 6.2 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.1 3.6 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.1 2.9 PID_AURORA_B_PATHWAY Aurora B signaling
0.1 5.3 PID_RB_1PATHWAY Regulation of retinoblastoma protein
0.1 5.5 PID_CDC42_PATHWAY CDC42 signaling events
0.1 2.0 PID_ATM_PATHWAY ATM pathway
0.0 2.2 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 1.4 PID_ATR_PATHWAY ATR signaling pathway
0.0 1.0 PID_IL2_PI3K_PATHWAY IL2 signaling events mediated by PI3K
0.0 2.5 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.0 7.2 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.3 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.0 1.1 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 2.6 PID_CMYB_PATHWAY C-MYB transcription factor network
0.0 1.5 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.0 0.5 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.0 0.9 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.0 1.1 PID_P73PATHWAY p73 transcription factor network
0.0 3.2 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.2 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.0 1.7 PID_PDGFRB_PATHWAY PDGFR-beta signaling pathway
0.0 0.6 PID_BMP_PATHWAY BMP receptor signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 11.6 REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.5 15.4 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.3 16.4 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.3 4.7 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.3 6.8 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.3 3.6 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.2 6.1 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.2 1.4 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.1 3.1 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 2.2 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.1 2.7 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 0.8 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 9.2 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 1.9 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 5.7 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.1 7.9 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 0.7 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.1 1.2 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 0.8 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM Genes involved in Abacavir transport and metabolism
0.1 0.8 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 2.1 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 2.2 REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 0.9 REACTOME_ERK_MAPK_TARGETS Genes involved in ERK/MAPK targets
0.0 0.8 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 2.6 REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION Genes involved in Extracellular matrix organization
0.0 0.6 REACTOME_FGFR4_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 1.3 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.2 REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 1.1 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 2.2 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 2.1 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 1.0 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 3.5 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 2.3 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.8 REACTOME_PEROXISOMAL_LIPID_METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.3 REACTOME_SHC_MEDIATED_SIGNALLING Genes involved in SHC-mediated signalling
0.0 1.0 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.4 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.8 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.9 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.3 REACTOME_PHASE_II_CONJUGATION Genes involved in Phase II conjugation
0.0 0.4 REACTOME_NEP_NS2_INTERACTS_WITH_THE_CELLULAR_EXPORT_MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.9 REACTOME_DESTABILIZATION_OF_MRNA_BY_AUF1_HNRNP_D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.2 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.0 0.7 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 1.2 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.0 0.4 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.2 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)