Motif ID: Neurod1

Z-value: 1.154


Transcription factors associated with Neurod1:

Gene SymbolEntrez IDGene Name
Neurod1 ENSMUSG00000034701.9 Neurod1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Neurod1mm10_v2_chr2_-_79456750_79456761-0.334.8e-02Click!


Activity profile for motif Neurod1.

activity profile for motif Neurod1


Sorted Z-values histogram for motif Neurod1

Sorted Z-values for motif Neurod1



Network of associatons between targets according to the STRING database.



First level regulatory network of Neurod1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_+_127866457 10.536 ENSMUST00000092058.3
BC089597
cDNA sequence BC089597
chr10_-_109010955 8.067 ENSMUST00000105276.1
ENSMUST00000064054.7
Syt1

synaptotagmin I

chr10_+_127801145 7.938 ENSMUST00000071646.1
Rdh16
retinol dehydrogenase 16
chr2_-_28563362 7.797 ENSMUST00000028161.5
Cel
carboxyl ester lipase
chr4_-_137409777 7.742 ENSMUST00000024200.6
Gm13011
predicted gene 13011
chr4_-_137430517 6.916 ENSMUST00000102522.4
Cela3b
chymotrypsin-like elastase family, member 3B
chr11_+_48837465 6.414 ENSMUST00000046903.5
Trim7
tripartite motif-containing 7
chr19_+_52264323 6.207 ENSMUST00000039652.4
Ins1
insulin I
chr7_-_142679533 6.174 ENSMUST00000162317.1
ENSMUST00000125933.1
ENSMUST00000105931.1
ENSMUST00000105930.1
ENSMUST00000105933.1
ENSMUST00000105932.1
ENSMUST00000000220.2
Ins2






insulin II






chr18_+_45268876 5.324 ENSMUST00000183850.1
ENSMUST00000066890.7
Kcnn2

potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2

chr10_+_127759780 5.039 ENSMUST00000128247.1
RP23-386P10.11
Protein Rdh9
chr11_-_5950018 4.748 ENSMUST00000102920.3
Gck
glucokinase
chr1_+_167598450 4.273 ENSMUST00000111386.1
ENSMUST00000111384.1
Rxrg

retinoid X receptor gamma

chr1_+_167598384 3.912 ENSMUST00000015987.3
Rxrg
retinoid X receptor gamma
chr7_+_27119909 3.803 ENSMUST00000003100.8
Cyp2f2
cytochrome P450, family 2, subfamily f, polypeptide 2
chr1_+_72824482 3.730 ENSMUST00000047328.4
Igfbp2
insulin-like growth factor binding protein 2
chr17_+_36942910 3.626 ENSMUST00000040498.5
Rnf39
ring finger protein 39
chr11_+_117809653 3.614 ENSMUST00000026649.7
ENSMUST00000177131.1
ENSMUST00000132298.1
Syngr2

Gm20708
synaptogyrin 2

predicted gene 20708
chr19_-_42202150 3.545 ENSMUST00000018966.7
Sfrp5
secreted frizzled-related sequence protein 5
chr3_+_14863495 3.426 ENSMUST00000029076.4
Car3
carbonic anhydrase 3
chr6_+_124570294 3.099 ENSMUST00000184647.1
C1rb
complement component 1, r subcomponent B
chr16_+_42907563 3.036 ENSMUST00000151244.1
ENSMUST00000114694.2
Zbtb20

zinc finger and BTB domain containing 20

chr7_-_114562945 2.994 ENSMUST00000119712.1
ENSMUST00000032908.8
Cyp2r1

cytochrome P450, family 2, subfamily r, polypeptide 1

chr5_-_151369172 2.973 ENSMUST00000067770.3
D730045B01Rik
RIKEN cDNA D730045B01 gene
chr10_+_127776374 2.948 ENSMUST00000136223.1
ENSMUST00000052652.6
Rdh9

retinol dehydrogenase 9

chr17_+_36943025 2.879 ENSMUST00000173072.1
Rnf39
ring finger protein 39
chr8_+_45507768 2.824 ENSMUST00000067065.7
ENSMUST00000098788.3
ENSMUST00000067107.7
ENSMUST00000171337.2
ENSMUST00000138049.1
ENSMUST00000141039.1
Sorbs2





sorbin and SH3 domain containing 2





chr14_-_57104693 2.674 ENSMUST00000055698.7
Gjb2
gap junction protein, beta 2
chr18_-_74961252 2.664 ENSMUST00000066532.4
Lipg
lipase, endothelial
chr10_-_127888688 2.597 ENSMUST00000047199.4
Rdh7
retinol dehydrogenase 7
chr16_+_56204313 2.589 ENSMUST00000160116.1
ENSMUST00000069936.7
Impg2

interphotoreceptor matrix proteoglycan 2

chr1_-_173367638 2.544 ENSMUST00000005470.4
ENSMUST00000111220.1
Cadm3

cell adhesion molecule 3

chr4_-_141623799 2.522 ENSMUST00000038661.7
Slc25a34
solute carrier family 25, member 34
chr7_+_28071230 2.501 ENSMUST00000138392.1
ENSMUST00000076648.7
Fcgbp

Fc fragment of IgG binding protein

chrX_+_139800795 2.473 ENSMUST00000054889.3
Cldn2
claudin 2
chr14_+_123659971 2.468 ENSMUST00000049681.7
Itgbl1
integrin, beta-like 1
chr9_+_44066993 2.387 ENSMUST00000034508.7
Usp2
ubiquitin specific peptidase 2
chr2_-_52558539 2.303 ENSMUST00000102760.3
ENSMUST00000102761.2
Cacnb4

calcium channel, voltage-dependent, beta 4 subunit

chr17_-_56005566 2.274 ENSMUST00000043785.6
Stap2
signal transducing adaptor family member 2
chr11_+_115462464 2.264 ENSMUST00000106532.3
ENSMUST00000092445.5
ENSMUST00000153466.1
Slc16a5


solute carrier family 16 (monocarboxylic acid transporters), member 5


chr7_-_19796789 2.160 ENSMUST00000108449.2
ENSMUST00000043822.7
Cblc

Casitas B-lineage lymphoma c

chr18_-_61911783 2.089 ENSMUST00000049378.8
ENSMUST00000166783.1
Ablim3

actin binding LIM protein family, member 3

chr10_+_107271827 2.077 ENSMUST00000020057.8
ENSMUST00000105280.3
Lin7a

lin-7 homolog A (C. elegans)

chr11_-_35980473 2.054 ENSMUST00000018993.6
Wwc1
WW, C2 and coiled-coil domain containing 1
chr16_-_46010212 2.053 ENSMUST00000130481.1
Plcxd2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr17_-_12851893 2.048 ENSMUST00000162389.1
ENSMUST00000162119.1
ENSMUST00000159223.1
Mas1


MAS1 oncogene


chr8_+_119394866 2.024 ENSMUST00000098367.4
Mlycd
malonyl-CoA decarboxylase
chr7_-_141437829 2.013 ENSMUST00000019226.7
Slc25a22
solute carrier family 25 (mitochondrial carrier, glutamate), member 22
chr5_+_151368683 1.994 ENSMUST00000181114.1
ENSMUST00000181555.1
1700028E10Rik

RIKEN cDNA 1700028E10 gene

chr2_-_160872985 1.984 ENSMUST00000109460.1
ENSMUST00000127201.1
Zhx3

zinc fingers and homeoboxes 3

chr17_+_46254017 1.968 ENSMUST00000095262.4
Lrrc73
leucine rich repeat containing 73
chr6_-_87690819 1.967 ENSMUST00000162547.1
1810020O05Rik
Riken cDNA 1810020O05 gene
chr7_-_141437587 1.931 ENSMUST00000172654.1
ENSMUST00000106006.1
Slc25a22

solute carrier family 25 (mitochondrial carrier, glutamate), member 22

chr19_-_24861828 1.889 ENSMUST00000047666.4
Pgm5
phosphoglucomutase 5
chr9_+_44067072 1.879 ENSMUST00000177054.1
Usp2
ubiquitin specific peptidase 2
chr1_+_131970589 1.853 ENSMUST00000027695.6
Slc45a3
solute carrier family 45, member 3
chr11_-_53773187 1.846 ENSMUST00000170390.1
Gm17334
predicted gene, 17334
chr10_+_127759721 1.840 ENSMUST00000073639.5
Rdh1
retinol dehydrogenase 1 (all trans)
chr2_-_84743655 1.797 ENSMUST00000181711.1
Gm19426
predicted gene, 19426
chr10_+_127849917 1.755 ENSMUST00000077530.2
Rdh19
retinol dehydrogenase 19
chr7_+_101394361 1.739 ENSMUST00000154239.1
ENSMUST00000098243.2
Arap1

ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1

chr17_+_56005672 1.713 ENSMUST00000133998.1
Mpnd
MPN domain containing
chr10_+_60106198 1.687 ENSMUST00000121820.2
Spock2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2
chr2_-_29253001 1.612 ENSMUST00000071201.4
Ntng2
netrin G2
chr9_-_50746501 1.599 ENSMUST00000034564.1
2310030G06Rik
RIKEN cDNA 2310030G06 gene
chr7_+_100009914 1.580 ENSMUST00000107084.1
Chrdl2
chordin-like 2
chr9_+_100643605 1.572 ENSMUST00000041418.6
Stag1
stromal antigen 1
chr5_-_86197846 1.569 ENSMUST00000094654.2
Gnrhr
gonadotropin releasing hormone receptor
chr18_+_84088077 1.562 ENSMUST00000060223.2
Zadh2
zinc binding alcohol dehydrogenase, domain containing 2
chr2_-_84775420 1.549 ENSMUST00000111641.1
Serping1
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr2_-_84775388 1.547 ENSMUST00000023994.3
Serping1
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr15_-_76090013 1.543 ENSMUST00000019516.4
Nrbp2
nuclear receptor binding protein 2
chr9_+_100643755 1.524 ENSMUST00000133388.1
Stag1
stromal antigen 1
chr3_-_84259812 1.515 ENSMUST00000107691.1
Trim2
tripartite motif-containing 2
chr2_-_52335134 1.514 ENSMUST00000075301.3
Neb
nebulin
chr10_-_95415484 1.513 ENSMUST00000172070.1
ENSMUST00000150432.1
Socs2

suppressor of cytokine signaling 2

chr2_+_96318014 1.513 ENSMUST00000135431.1
ENSMUST00000162807.2
Lrrc4c

leucine rich repeat containing 4C

chr9_-_63602417 1.510 ENSMUST00000171243.1
ENSMUST00000163982.1
ENSMUST00000163624.1
Iqch


IQ motif containing H


chr7_+_27607997 1.498 ENSMUST00000142365.1
Akt2
thymoma viral proto-oncogene 2
chr8_-_119635553 1.484 ENSMUST00000061828.3
Kcng4
potassium voltage-gated channel, subfamily G, member 4
chr7_-_90129339 1.473 ENSMUST00000181189.1
2310010J17Rik
RIKEN cDNA 2310010J17 gene
chr5_+_90460889 1.461 ENSMUST00000031314.8
Alb
albumin
chr7_-_98361275 1.449 ENSMUST00000094161.4
ENSMUST00000164726.1
ENSMUST00000167405.1
Tsku


tsukushi


chr6_-_136171722 1.439 ENSMUST00000053880.6
Grin2b
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chr8_+_127064107 1.430 ENSMUST00000162536.1
ENSMUST00000026921.6
ENSMUST00000162665.1
ENSMUST00000160766.1
ENSMUST00000162602.1
ENSMUST00000162531.1
ENSMUST00000160581.1
ENSMUST00000161355.1
ENSMUST00000159537.1
Pard3








par-3 (partitioning defective 3) homolog (C. elegans)








chr9_-_63602464 1.429 ENSMUST00000080527.5
ENSMUST00000042322.4
Iqch

IQ motif containing H

chr19_+_4082473 1.424 ENSMUST00000159148.1
Cabp2
calcium binding protein 2
chr9_-_105960642 1.416 ENSMUST00000165165.2
Col6a5
collagen, type VI, alpha 5
chr15_+_25622525 1.400 ENSMUST00000110457.1
ENSMUST00000137601.1
Myo10

myosin X

chr19_+_57611020 1.370 ENSMUST00000077282.5
Atrnl1
attractin like 1
chr18_-_77565050 1.351 ENSMUST00000182153.1
ENSMUST00000182146.1
ENSMUST00000026494.7
ENSMUST00000182024.1
Rnf165



ring finger protein 165



chr4_+_80910646 1.348 ENSMUST00000055922.3
Lurap1l
leucine rich adaptor protein 1-like
chr6_-_97252779 1.336 ENSMUST00000095655.2
Lmod3
leiomodin 3 (fetal)
chr1_-_91413163 1.274 ENSMUST00000086851.1
Hes6
hairy and enhancer of split 6
chr2_-_10130638 1.272 ENSMUST00000042290.7
Itih2
inter-alpha trypsin inhibitor, heavy chain 2
chr11_+_97030130 1.267 ENSMUST00000153482.1
Scrn2
secernin 2
chr6_+_56017489 1.266 ENSMUST00000052827.4
Ppp1r17
protein phosphatase 1, regulatory subunit 17
chr7_-_98361310 1.260 ENSMUST00000165257.1
Tsku
tsukushi
chr17_+_34670535 1.244 ENSMUST00000168533.1
ENSMUST00000087399.4
Tnxb

tenascin XB

chr1_-_192834719 1.242 ENSMUST00000057543.2
A730013G03Rik
RIKEN cDNA A730013G03 gene
chr3_+_96246685 1.234 ENSMUST00000176059.1
ENSMUST00000177796.1
Hist2h3c1

histone cluster 2, H3c1

chr1_+_162639148 1.220 ENSMUST00000028020.9
Myoc
myocilin
chr13_-_60177357 1.180 ENSMUST00000065086.4
Gas1
growth arrest specific 1
chr11_+_97029925 1.180 ENSMUST00000021249.4
Scrn2
secernin 2
chr1_+_162570515 1.147 ENSMUST00000132158.1
ENSMUST00000135241.1
Vamp4

vesicle-associated membrane protein 4

chr7_-_45061706 1.147 ENSMUST00000107832.1
Prrg2
proline-rich Gla (G-carboxyglutamic acid) polypeptide 2
chr9_+_100643448 1.142 ENSMUST00000146312.1
ENSMUST00000129269.1
Stag1

stromal antigen 1

chr6_+_54264839 1.128 ENSMUST00000146114.1
Chn2
chimerin (chimaerin) 2
chr18_-_12819842 1.126 ENSMUST00000119043.1
Osbpl1a
oxysterol binding protein-like 1A
chr11_+_117809687 1.122 ENSMUST00000120928.1
ENSMUST00000175737.1
Syngr2

synaptogyrin 2

chr7_+_128523576 1.119 ENSMUST00000033136.7
Bag3
BCL2-associated athanogene 3
chr19_+_5038826 1.103 ENSMUST00000053705.6
B3gnt1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1
chr7_+_27607748 1.098 ENSMUST00000136962.1
Akt2
thymoma viral proto-oncogene 2
chr10_-_128922888 1.094 ENSMUST00000135161.1
Rdh5
retinol dehydrogenase 5
chr9_-_107710475 1.072 ENSMUST00000080560.3
Sema3f
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr11_+_67798269 1.065 ENSMUST00000168612.1
ENSMUST00000040574.4
Dhrs7c

dehydrogenase/reductase (SDR family) member 7C

chr10_+_79973737 1.063 ENSMUST00000149148.1
Grin3b
glutamate receptor, ionotropic, NMDA3B
chr7_-_45870928 1.052 ENSMUST00000146672.1
Grin2d
glutamate receptor, ionotropic, NMDA2D (epsilon 4)
chr19_-_32712287 1.052 ENSMUST00000070210.4
Atad1
ATPase family, AAA domain containing 1
chrX_-_48208566 1.041 ENSMUST00000037960.4
Zdhhc9
zinc finger, DHHC domain containing 9
chr7_+_140704165 1.039 ENSMUST00000080681.3
Olfr541
olfactory receptor 541
chr16_+_84774123 1.033 ENSMUST00000114195.1
Jam2
junction adhesion molecule 2
chr11_+_78503449 1.025 ENSMUST00000001130.6
ENSMUST00000125670.2
Sebox

SEBOX homeobox

chr11_+_70030023 1.017 ENSMUST00000143920.2
Dlg4
discs, large homolog 4 (Drosophila)
chr11_-_116131073 1.006 ENSMUST00000106440.2
ENSMUST00000067632.3
Trim65

tripartite motif-containing 65

chr4_-_22488296 1.001 ENSMUST00000178174.1
Pou3f2
POU domain, class 3, transcription factor 2
chr5_-_143138200 0.996 ENSMUST00000164536.2
Olfr718-ps1
olfactory receptor 718, pseudogene 1
chr11_-_99556846 0.993 ENSMUST00000092699.2
Krtap3-2
keratin associated protein 3-2
chr11_-_119086221 0.978 ENSMUST00000026665.7
Cbx4
chromobox 4
chr4_-_25281801 0.974 ENSMUST00000102994.3
Ufl1
UFM1 specific ligase 1
chr3_-_53863764 0.974 ENSMUST00000122330.1
ENSMUST00000146598.1
Ufm1

ubiquitin-fold modifier 1

chr4_-_129227883 0.967 ENSMUST00000106051.1
C77080
expressed sequence C77080
chr7_-_45061651 0.964 ENSMUST00000007981.3
ENSMUST00000107831.1
Prrg2

proline-rich Gla (G-carboxyglutamic acid) polypeptide 2

chr10_-_92375367 0.958 ENSMUST00000182870.1
Gm20757
predicted gene, 20757
chr2_+_69219971 0.950 ENSMUST00000005364.5
ENSMUST00000112317.2
G6pc2

glucose-6-phosphatase, catalytic, 2

chr15_+_8968389 0.943 ENSMUST00000053308.9
ENSMUST00000166524.1
Ranbp3l

RAN binding protein 3-like

chr5_-_142608785 0.935 ENSMUST00000037048.7
Mmd2
monocyte to macrophage differentiation-associated 2
chrX_-_48208870 0.911 ENSMUST00000088935.3
Zdhhc9
zinc finger, DHHC domain containing 9
chr11_+_109485606 0.907 ENSMUST00000106697.1
Arsg
arylsulfatase G
chr5_-_28210168 0.907 ENSMUST00000117098.1
Cnpy1
canopy 1 homolog (zebrafish)
chr9_+_78175898 0.898 ENSMUST00000180974.1
C920006O11Rik
RIKEN cDNA C920006O11 gene
chr13_+_51846673 0.898 ENSMUST00000021903.2
Gadd45g
growth arrest and DNA-damage-inducible 45 gamma
chr7_+_121707189 0.890 ENSMUST00000065310.2
1700069B07Rik
RIKEN cDNA 1700069B07 gene
chr1_-_180483410 0.879 ENSMUST00000136521.1
ENSMUST00000179826.1
6330403A02Rik

RIKEN cDNA 6330403A02 gene

chr3_-_73708399 0.878 ENSMUST00000029367.5
Bche
butyrylcholinesterase
chr13_-_22219820 0.872 ENSMUST00000057516.1
Vmn1r193
vomeronasal 1 receptor 193
chr11_-_98329641 0.863 ENSMUST00000041685.6
Neurod2
neurogenic differentiation 2
chr2_+_163506808 0.848 ENSMUST00000143911.1
Hnf4a
hepatic nuclear factor 4, alpha
chr10_+_63100156 0.847 ENSMUST00000044059.3
Atoh7
atonal homolog 7 (Drosophila)
chr8_-_119635346 0.845 ENSMUST00000164382.1
Kcng4
potassium voltage-gated channel, subfamily G, member 4
chr5_-_74677792 0.840 ENSMUST00000117525.1
ENSMUST00000153543.1
ENSMUST00000039744.6
ENSMUST00000113531.2
ENSMUST00000121690.1
Lnx1




ligand of numb-protein X 1




chr8_-_107065632 0.833 ENSMUST00000034393.5
Tmed6
transmembrane emp24 protein transport domain containing 6
chr10_-_95415283 0.817 ENSMUST00000119917.1
Socs2
suppressor of cytokine signaling 2
chr7_-_4970961 0.814 ENSMUST00000144863.1
Gm1078
predicted gene 1078
chr7_-_142229971 0.812 ENSMUST00000097942.2
Krtap5-5
keratin associated protein 5-5
chr7_-_140163014 0.800 ENSMUST00000050585.5
Olfr522
olfactory receptor 522
chr4_-_148149684 0.799 ENSMUST00000126615.1
Fbxo6
F-box protein 6
chr15_+_99099412 0.778 ENSMUST00000061295.6
Dnajc22
DnaJ (Hsp40) homolog, subfamily C, member 22
chr4_-_20778852 0.775 ENSMUST00000102998.3
Nkain3
Na+/K+ transporting ATPase interacting 3
chr3_+_135438722 0.772 ENSMUST00000166033.1
Ube2d3
ubiquitin-conjugating enzyme E2D 3
chr2_-_118762607 0.769 ENSMUST00000059997.8
A430105I19Rik
RIKEN cDNA A430105I19 gene
chr7_-_28302238 0.755 ENSMUST00000108315.3
Dll3
delta-like 3 (Drosophila)
chr3_-_88254706 0.753 ENSMUST00000171887.1
Rhbg
Rhesus blood group-associated B glycoprotein
chr6_+_97807014 0.752 ENSMUST00000043637.7
Mitf
microphthalmia-associated transcription factor
chr15_+_101115738 0.749 ENSMUST00000070875.6
Ankrd33
ankyrin repeat domain 33
chr7_-_140401044 0.745 ENSMUST00000080153.1
Olfr531
olfactory receptor 531
chrX_-_20291776 0.743 ENSMUST00000072451.4
Slc9a7
solute carrier family 9 (sodium/hydrogen exchanger), member 7
chr11_+_67774608 0.742 ENSMUST00000181566.1
Gm12302
predicted gene 12302
chr14_+_70530819 0.738 ENSMUST00000047331.6
Lgi3
leucine-rich repeat LGI family, member 3
chr4_-_42168603 0.737 ENSMUST00000098121.3
Gm13305
predicted gene 13305
chr10_+_80142295 0.733 ENSMUST00000003156.8
Atp5d
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
chr11_+_102836296 0.731 ENSMUST00000021302.8
ENSMUST00000107072.1
Higd1b

HIG1 domain family, member 1B

chr2_-_103372725 0.730 ENSMUST00000139065.1
A930006I01Rik
RIKEN cDNA A930006I01 gene
chr17_-_14203695 0.729 ENSMUST00000053218.5
Dact2
dapper homolog 2, antagonist of beta-catenin (xenopus)
chr11_+_72607221 0.728 ENSMUST00000021148.6
ENSMUST00000138247.1
Ube2g1

ubiquitin-conjugating enzyme E2G 1

chr10_-_121476248 0.726 ENSMUST00000026902.7
Rassf3
Ras association (RalGDS/AF-6) domain family member 3
chr18_-_77186257 0.725 ENSMUST00000097520.2
Gm7276
predicted gene 7276
chrX_-_36645359 0.723 ENSMUST00000051906.6
Akap17b
A kinase (PRKA) anchor protein 17B
chr8_-_71381907 0.718 ENSMUST00000002466.8
Nr2f6
nuclear receptor subfamily 2, group F, member 6
chr1_+_87205799 0.714 ENSMUST00000027470.7
Chrng
cholinergic receptor, nicotinic, gamma polypeptide
chr1_+_143640664 0.710 ENSMUST00000038252.2
B3galt2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr2_-_174438996 0.709 ENSMUST00000016400.8
Ctsz
cathepsin Z
chr7_-_102065044 0.703 ENSMUST00000130074.1
ENSMUST00000131104.1
ENSMUST00000096639.5
Rnf121


ring finger protein 121


chr10_+_127420334 0.703 ENSMUST00000171434.1
R3hdm2
R3H domain containing 2
chr2_-_46442681 0.697 ENSMUST00000123911.1
Gm13470
predicted gene 13470
chr11_+_99879187 0.680 ENSMUST00000078442.3
Gm11567
predicted gene 11567
chr5_+_30232581 0.678 ENSMUST00000145167.1
Ept1
ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific)
chr10_+_67538563 0.672 ENSMUST00000127820.1
Egr2
early growth response 2
chr5_-_28210022 0.671 ENSMUST00000118882.1
Cnpy1
canopy 1 homolog (zebrafish)
chr17_+_8434423 0.670 ENSMUST00000074667.2
T
brachyury
chr7_+_3694512 0.670 ENSMUST00000108627.3
Tsen34
tRNA splicing endonuclease 34 homolog (S. cerevisiae)
chr4_-_25281752 0.668 ENSMUST00000038705.7
Ufl1
UFM1 specific ligase 1
chr3_+_86084434 0.667 ENSMUST00000107664.2
Sh3d19
SH3 domain protein D19
chr2_-_173276144 0.666 ENSMUST00000139306.1
Pmepa1
prostate transmembrane protein, androgen induced 1
chr2_+_126034967 0.655 ENSMUST00000110442.1
Fgf7
fibroblast growth factor 7
chr10_+_61175206 0.648 ENSMUST00000079235.5
Tbata
thymus, brain and testes associated
chr7_+_127471009 0.642 ENSMUST00000133938.1
Prr14
proline rich 14
chr7_-_19861299 0.638 ENSMUST00000014830.7
Ceacam16
carcinoembryonic antigen-related cell adhesion molecule 16
chr3_+_9250602 0.637 ENSMUST00000155203.1
Zbtb10
zinc finger and BTB domain containing 10
chr2_-_90022064 0.634 ENSMUST00000099758.1
Olfr1264
olfactory receptor 1264

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 6.2 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861) neuron projection maintenance(GO:1990535)
1.6 10.9 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
1.2 3.5 GO:2000040 regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
1.0 3.1 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
1.0 3.8 GO:0042196 chlorinated hydrocarbon metabolic process(GO:0042196) halogenated hydrocarbon metabolic process(GO:0042197)
0.9 4.7 GO:0034287 detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.8 5.3 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.7 8.1 GO:0005513 detection of calcium ion(GO:0005513)
0.7 2.0 GO:2001293 malonyl-CoA metabolic process(GO:2001293)
0.7 2.7 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
0.6 7.8 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.5 2.7 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.5 1.9 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.4 2.6 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.4 2.6 GO:0097473 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.4 2.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.4 1.2 GO:0038129 ERBB3 signaling pathway(GO:0038129)
0.4 1.2 GO:0051659 maintenance of mitochondrion location(GO:0051659)
0.3 2.1 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.3 0.9 GO:1900673 olefin metabolic process(GO:1900673)
0.3 0.9 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.3 0.8 GO:1902569 negative regulation of activation of Janus kinase activity(GO:1902569)
0.3 1.1 GO:0021660 rhombomere formation(GO:0021594) rhombomere 3 formation(GO:0021660) rhombomere 5 morphogenesis(GO:0021664) rhombomere 5 formation(GO:0021666)
0.3 0.8 GO:0007386 compartment pattern specification(GO:0007386)
0.2 2.5 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.2 1.0 GO:1904451 regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904451) positive regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904453)
0.2 0.9 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.2 2.3 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.2 0.7 GO:0003257 positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003257)
0.2 8.2 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.2 0.6 GO:0061033 secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.2 3.9 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.2 1.2 GO:0003383 apical constriction(GO:0003383)
0.2 0.6 GO:0060300 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874) regulation of cytokine activity(GO:0060300) negative regulation of sensory perception of pain(GO:1904057)
0.2 4.3 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.2 0.8 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.2 1.7 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.2 1.1 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.2 0.7 GO:0072061 inner medullary collecting duct development(GO:0072061)
0.2 0.7 GO:0044778 meiotic DNA integrity checkpoint(GO:0044778)
0.2 1.1 GO:0097491 trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.2 2.0 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.2 0.9 GO:0014016 neuroblast differentiation(GO:0014016)
0.2 0.7 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.2 1.3 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.2 2.3 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.2 4.3 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.1 2.7 GO:0016264 gap junction assembly(GO:0016264)
0.1 0.4 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.1 0.4 GO:0090425 hepatocyte cell migration(GO:0002194) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.1 0.4 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.1 0.6 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.1 1.6 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.1 0.6 GO:0034769 basement membrane disassembly(GO:0034769)
0.1 2.5 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 0.4 GO:0007208 phospholipase C-activating serotonin receptor signaling pathway(GO:0007208)
0.1 0.5 GO:0008594 photoreceptor cell morphogenesis(GO:0008594)
0.1 1.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 1.0 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.1 0.6 GO:1902732 positive regulation of chondrocyte proliferation(GO:1902732)
0.1 0.7 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 2.3 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.1 1.2 GO:0042473 outer ear morphogenesis(GO:0042473)
0.1 0.5 GO:2000210 positive regulation of anoikis(GO:2000210)
0.1 0.7 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.1 1.1 GO:0098719 sodium ion import across plasma membrane(GO:0098719)
0.1 0.3 GO:1902340 telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340)
0.1 1.1 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.1 0.7 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 0.5 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 3.4 GO:0006730 one-carbon metabolic process(GO:0006730)
0.1 0.5 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.1 0.3 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.1 0.4 GO:0010288 response to lead ion(GO:0010288)
0.1 1.1 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.1 0.9 GO:0042095 interferon-gamma biosynthetic process(GO:0042095)
0.1 3.1 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 1.6 GO:0009649 entrainment of circadian clock(GO:0009649)
0.1 0.2 GO:0003273 cell migration involved in endocardial cushion formation(GO:0003273)
0.1 0.7 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.1 0.2 GO:0009624 response to nematode(GO:0009624)
0.1 0.6 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.1 0.3 GO:0021542 dentate gyrus development(GO:0021542)
0.1 1.7 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.1 0.8 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.1 0.3 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.1 1.1 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.1 2.6 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 0.3 GO:0060279 positive regulation of ovulation(GO:0060279)
0.1 0.3 GO:0061056 sclerotome development(GO:0061056)
0.1 6.9 GO:0008203 cholesterol metabolic process(GO:0008203)
0.0 0.3 GO:0021960 anterior commissure morphogenesis(GO:0021960)
0.0 0.5 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 3.1 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 1.1 GO:0051205 protein insertion into membrane(GO:0051205)
0.0 0.5 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.3 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.1 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
0.0 0.5 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.6 GO:0021854 hypothalamus development(GO:0021854)
0.0 1.8 GO:0001523 retinoid metabolic process(GO:0001523)
0.0 0.8 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.7 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 1.4 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.2 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.4 GO:1902414 protein localization to cell junction(GO:1902414)
0.0 0.7 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.4 GO:0050957 equilibrioception(GO:0050957)
0.0 0.4 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 1.3 GO:0006693 prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.0 1.3 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.3 GO:0031179 peptide modification(GO:0031179)
0.0 4.4 GO:0015758 glucose transport(GO:0015758)
0.0 0.3 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.2 GO:0006517 protein deglycosylation(GO:0006517)
0.0 1.1 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.9 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.7 GO:2000678 negative regulation of transcription regulatory region DNA binding(GO:2000678)
0.0 2.2 GO:1903749 positive regulation of establishment of protein localization to mitochondrion(GO:1903749) positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 0.1 GO:0061739 protein lipidation involved in autophagosome assembly(GO:0061739)
0.0 0.2 GO:0043589 skin morphogenesis(GO:0043589)
0.0 0.7 GO:0017157 regulation of exocytosis(GO:0017157)
0.0 3.7 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.9 GO:0019835 cytolysis(GO:0019835)
0.0 0.9 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.7 GO:0035094 response to nicotine(GO:0035094)
0.0 0.1 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.0 2.6 GO:0006839 mitochondrial transport(GO:0006839)
0.0 2.9 GO:0007601 visual perception(GO:0007601)
0.0 0.5 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.0 1.1 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.0 0.4 GO:0007568 aging(GO:0007568)
0.0 0.4 GO:0042772 ribosomal small subunit assembly(GO:0000028) DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.0 1.6 GO:0099132 ATP hydrolysis coupled cation transmembrane transport(GO:0099132)
0.0 1.0 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.6 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.1 GO:0046864 retinol transport(GO:0034633) nose morphogenesis(GO:0043585) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865) alveolar primary septum development(GO:0061143)
0.0 0.4 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.0 0.1 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.0 0.1 GO:0030035 microspike assembly(GO:0030035)
0.0 0.4 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895)
0.0 1.0 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.5 GO:0019236 response to pheromone(GO:0019236)
0.0 3.2 GO:0006605 protein targeting(GO:0006605)
0.0 0.8 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.2 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.2 GO:0048665 neuron fate specification(GO:0048665)
0.0 0.5 GO:0097503 sialylation(GO:0097503)
0.0 0.6 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.0 0.3 GO:2000311 regulation of AMPA receptor activity(GO:2000311)
0.0 0.7 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 1.0 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.3 GO:0097352 autophagosome maturation(GO:0097352)
0.0 1.0 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.0 0.7 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.6 GO:0045214 sarcomere organization(GO:0045214)
0.0 0.2 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.1 GO:0038169 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.0 0.2 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.1 GO:0071498 cellular response to fluid shear stress(GO:0071498)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.6 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.4 9.7 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285)
0.4 1.9 GO:0005914 spot adherens junction(GO:0005914)
0.3 2.1 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.3 4.7 GO:0045180 basal cortex(GO:0045180)
0.3 7.8 GO:0042588 zymogen granule(GO:0042588)
0.2 1.0 GO:0097574 lateral part of cell(GO:0097574) basolateral part of cell(GO:1990794) rod bipolar cell terminal bouton(GO:1990795) photoreceptor cell terminal bouton(GO:1990796)
0.2 6.2 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.2 0.9 GO:0044307 dendritic branch(GO:0044307)
0.2 0.6 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.2 9.9 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.2 1.4 GO:0033269 internode region of axon(GO:0033269)
0.2 2.7 GO:0097449 astrocyte projection(GO:0097449)
0.2 1.3 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.2 2.6 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 0.4 GO:0018444 translation release factor complex(GO:0018444)
0.1 2.0 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.1 2.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 5.3 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 0.7 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.1 0.4 GO:0071942 XPC complex(GO:0071942)
0.1 0.7 GO:0030896 checkpoint clamp complex(GO:0030896)
0.1 0.3 GO:0000814 ESCRT II complex(GO:0000814)
0.1 0.5 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 1.2 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 1.2 GO:0035748 myelin sheath abaxonal region(GO:0035748)
0.1 0.3 GO:0043512 inhibin A complex(GO:0043512)
0.1 4.7 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 2.0 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 0.8 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.1 0.5 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 0.9 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 0.3 GO:1990745 EARP complex(GO:1990745)
0.1 3.5 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 0.6 GO:0042587 glycogen granule(GO:0042587)
0.1 8.9 GO:0072562 blood microparticle(GO:0072562)
0.1 0.6 GO:0070545 PeBoW complex(GO:0070545)
0.1 1.1 GO:0032993 protein-DNA complex(GO:0032993)
0.0 2.1 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.7 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.6 GO:0035102 PRC1 complex(GO:0035102)
0.0 1.2 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.8 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.8 GO:0045095 keratin filament(GO:0045095)
0.0 0.6 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.7 GO:0099738 cell cortex region(GO:0099738)
0.0 0.8 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.5 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.6 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 2.1 GO:0032587 ruffle membrane(GO:0032587)
0.0 1.3 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.7 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.5 GO:0030175 filopodium(GO:0030175)
0.0 0.7 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 5.5 GO:0030141 secretory granule(GO:0030141)
0.0 0.4 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.2 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 0.3 GO:0000421 autophagosome membrane(GO:0000421)
0.0 1.2 GO:0005581 collagen trimer(GO:0005581)
0.0 1.8 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.5 GO:0031941 filamentous actin(GO:0031941)
0.0 0.2 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 5.4 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 0.1 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.3 GO:0031201 SNARE complex(GO:0031201)
0.0 0.4 GO:0060076 excitatory synapse(GO:0060076)
0.0 0.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.0 GO:0070436 Grb2-EGFR complex(GO:0070436)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 7.8 GO:0004771 sterol esterase activity(GO:0004771) retinyl-palmitate esterase activity(GO:0050253)
2.0 8.1 GO:0030348 syntaxin-3 binding(GO:0030348)
1.3 5.3 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.8 19.2 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.8 8.2 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.6 1.8 GO:0051448 gonadotropin-releasing hormone receptor activity(GO:0004968) growth hormone-releasing hormone receptor activity(GO:0016520) gonadotropin-releasing hormone binding(GO:0051448)
0.5 1.6 GO:0071568 UFM1 transferase activity(GO:0071568)
0.5 1.6 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.5 2.3 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.5 1.9 GO:0008515 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.4 2.7 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.4 3.7 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.4 6.2 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.3 2.1 GO:0097016 L27 domain binding(GO:0097016)
0.3 1.0 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.3 3.9 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.3 2.0 GO:0001595 angiotensin receptor activity(GO:0001595)
0.3 3.4 GO:0016151 nickel cation binding(GO:0016151)
0.3 0.8 GO:0070540 stearic acid binding(GO:0070540)
0.2 5.3 GO:0019825 oxygen binding(GO:0019825)
0.2 4.7 GO:0005536 glucose binding(GO:0005536)
0.2 0.9 GO:0004104 cholinesterase activity(GO:0004104)
0.2 1.4 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.2 0.7 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.2 1.2 GO:0032027 myosin light chain binding(GO:0032027)
0.2 0.5 GO:0042015 interleukin-20 binding(GO:0042015)
0.2 2.7 GO:0005243 gap junction channel activity(GO:0005243)
0.2 1.3 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.2 3.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 1.9 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.1 3.1 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
0.1 1.0 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.1 0.4 GO:0001587 Gq/11-coupled serotonin receptor activity(GO:0001587)
0.1 1.1 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 0.5 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 0.6 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.1 0.7 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.1 1.3 GO:0005523 tropomyosin binding(GO:0005523)
0.1 6.2 GO:0005158 insulin receptor binding(GO:0005158)
0.1 2.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 3.1 GO:0001848 complement binding(GO:0001848)
0.1 0.7 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.6 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.1 1.1 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 0.6 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 1.6 GO:0016805 dipeptidase activity(GO:0016805)
0.1 0.2 GO:0019002 GMP binding(GO:0019002)
0.1 1.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 0.9 GO:0070097 delta-catenin binding(GO:0070097)
0.1 0.3 GO:0016842 amidine-lyase activity(GO:0016842)
0.1 1.1 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.1 1.1 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.4 GO:0001515 opioid peptide activity(GO:0001515)
0.1 2.2 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 0.6 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.4 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 0.4 GO:0050692 DBD domain binding(GO:0050692)
0.1 0.4 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 0.5 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 3.6 GO:0005549 odorant binding(GO:0005549)
0.0 3.0 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.8 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 2.1 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.4 GO:0008494 translation activator activity(GO:0008494)
0.0 0.2 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.3 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 2.3 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.3 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.7 GO:0022848 acetylcholine-gated cation-selective channel activity(GO:0022848)
0.0 4.6 GO:0015645 fatty acid ligase activity(GO:0015645)
0.0 0.4 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 1.6 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 1.4 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 1.8 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.7 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 1.0 GO:0032183 SUMO binding(GO:0032183)
0.0 1.5 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.6 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.7 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.5 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.3 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.7 GO:0004180 carboxypeptidase activity(GO:0004180)
0.0 0.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.8 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 0.4 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 1.1 GO:0070888 E-box binding(GO:0070888)
0.0 0.4 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.5 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 7.2 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.8 GO:0005112 Notch binding(GO:0005112)
0.0 0.3 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.6 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.6 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 2.6 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.7 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.9 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 1.1 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.3 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.2 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.7 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.8 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.9 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.2 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.6 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.3 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.2 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.4 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.2 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.1 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.0 0.4 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 1.9 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.1 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.8 GO:0046332 SMAD binding(GO:0046332)
0.0 0.5 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.4 GO:0017091 AU-rich element binding(GO:0017091)
0.0 1.4 GO:0008201 heparin binding(GO:0008201)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 8.2 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 7.6 SIG_CD40PATHWAYMAP Genes related to CD40 signaling
0.1 2.6 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 7.1 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 4.3 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.1 3.0 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.0 1.0 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 1.5 PID_INTEGRIN_A4B1_PATHWAY Alpha4 beta1 integrin signaling events
0.0 1.1 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.0 1.6 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.0 8.9 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.3 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 0.6 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.0 0.8 ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.9 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.0 0.8 PID_NFKAPPAB_CANONICAL_PATHWAY Canonical NF-kappaB pathway
0.0 1.4 SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES Genes related to the insulin receptor pathway
0.0 1.1 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.0 4.3 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.4 PID_NOTCH_PATHWAY Notch signaling pathway
0.0 0.9 PID_ERBB4_PATHWAY ErbB4 signaling events
0.0 1.4 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.0 1.0 PID_KIT_PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.7 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.4 PID_PS1_PATHWAY Presenilin action in Notch and Wnt signaling
0.0 4.6 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 0.5 PID_CERAMIDE_PATHWAY Ceramide signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 8.1 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.2 1.8 REACTOME_HORMONE_LIGAND_BINDING_RECEPTORS Genes involved in Hormone ligand-binding receptors
0.2 7.4 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.2 3.7 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2 1.5 REACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS Genes involved in Recycling of bile acids and salts
0.1 3.1 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.1 2.7 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.1 3.4 REACTOME_UNBLOCKING_OF_NMDA_RECEPTOR_GLUTAMATE_BINDING_AND_ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.1 3.0 REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 0.9 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 8.8 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 3.9 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.1 0.9 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport
0.1 1.3 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 1.9 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.1 2.1 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.1 1.6 REACTOME_KERATAN_SULFATE_BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.1 2.3 REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING Genes involved in Growth hormone receptor signaling
0.1 0.7 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.9 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 6.7 REACTOME_POTASSIUM_CHANNELS Genes involved in Potassium Channels
0.0 1.6 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.0 0.3 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.0 0.6 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.6 REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.7 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.0 2.1 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.0 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.0 0.6 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.8 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.7 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 0.6 REACTOME_ACTIVATED_POINT_MUTANTS_OF_FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 0.7 REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 1.0 REACTOME_GLUCOSE_TRANSPORT Genes involved in Glucose transport
0.0 2.5 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.7 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 1.5 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.4 REACTOME_FORMATION_OF_INCISION_COMPLEX_IN_GG_NER Genes involved in Formation of incision complex in GG-NER
0.0 1.5 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.2 REACTOME_SEROTONIN_RECEPTORS Genes involved in Serotonin receptors
0.0 0.5 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.6 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 1.1 REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.4 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.4 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)