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GSE58827: Dynamics of the Mouse Liver

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Results for Nfat5

Z-value: 0.58

Motif logo

Transcription factors associated with Nfat5

Gene Symbol Gene ID Gene Info
ENSMUSG00000003847.10 nuclear factor of activated T cells 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nfat5mm10_v2_chr8_+_107293463_107293483-0.067.4e-01Click!

Activity profile of Nfat5 motif

Sorted Z-values of Nfat5 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_97417730 5.65 ENSMUST00000043077.7
thyroid hormone responsive
chr2_+_68117713 5.18 ENSMUST00000112346.2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr1_+_88070765 2.96 ENSMUST00000073772.4
UDP glucuronosyltransferase 1 family, polypeptide A9
chr10_-_95415484 2.85 ENSMUST00000172070.1
ENSMUST00000150432.1
suppressor of cytokine signaling 2
chr4_-_49506538 2.77 ENSMUST00000043056.2
bile acid-Coenzyme A: amino acid N-acyltransferase
chr10_-_109010955 2.72 ENSMUST00000105276.1
ENSMUST00000064054.7
synaptotagmin I
chr3_-_98724543 2.34 ENSMUST00000107022.1
ENSMUST00000107021.1
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
chr1_+_88055377 2.20 ENSMUST00000138182.1
ENSMUST00000113142.3
UDP glycosyltransferase 1 family, polypeptide A10
chr1_+_88055467 2.13 ENSMUST00000173325.1
UDP glycosyltransferase 1 family, polypeptide A10
chr10_-_95415283 1.87 ENSMUST00000119917.1
suppressor of cytokine signaling 2
chr6_+_91684061 1.68 ENSMUST00000032185.7
solute carrier family 6 (neurotransmitter transporter, taurine), member 6
chr10_-_78351711 1.66 ENSMUST00000105390.1
1-acylglycerol-3-phosphate O-acyltransferase 3
chr10_-_78352053 1.65 ENSMUST00000105388.1
1-acylglycerol-3-phosphate O-acyltransferase 3
chr4_-_82505707 1.64 ENSMUST00000107248.1
ENSMUST00000107247.1
nuclear factor I/B
chr1_+_24678536 1.61 ENSMUST00000095062.3
LMBR1 domain containing 1
chr10_+_4611971 1.59 ENSMUST00000105590.1
ENSMUST00000067086.7
estrogen receptor 1 (alpha)
chr5_-_104021919 1.53 ENSMUST00000031251.9
hydroxysteroid (17-beta) dehydrogenase 11
chr5_-_104021799 1.52 ENSMUST00000119025.1
hydroxysteroid (17-beta) dehydrogenase 11
chrX_+_38772671 1.50 ENSMUST00000050744.5
RIKEN cDNA 6030498E09 gene
chr7_-_30598863 1.49 ENSMUST00000108150.1
zinc finger and BTB domain containing 32
chr10_-_78352212 1.41 ENSMUST00000146899.1
1-acylglycerol-3-phosphate O-acyltransferase 3
chr12_-_83597140 1.39 ENSMUST00000048319.4
zinc finger, FYVE domain containing 1
chr14_+_17660956 1.39 ENSMUST00000022303.7
ENSMUST00000091471.4
thyroid hormone receptor beta
chr5_+_120511168 1.32 ENSMUST00000068326.7
solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
chr15_-_75894474 1.31 ENSMUST00000023237.6
nicotinate phosphoribosyltransferase domain containing 1
chr5_+_120511213 1.30 ENSMUST00000111890.2
ENSMUST00000076051.5
ENSMUST00000147496.1
solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
chr1_+_193301953 1.29 ENSMUST00000016315.9
laminin, beta 3
chr10_-_78351690 1.26 ENSMUST00000166360.1
1-acylglycerol-3-phosphate O-acyltransferase 3
chr12_+_36090379 1.26 ENSMUST00000071825.5
predicted gene 5434
chr9_-_71771535 1.24 ENSMUST00000122065.1
ENSMUST00000121322.1
ENSMUST00000072899.2
cingulin-like 1
chr19_+_25236959 1.19 ENSMUST00000049400.8
KN motif and ankyrin repeat domains 1
chr11_-_88863717 1.17 ENSMUST00000107904.2
A kinase (PRKA) anchor protein 1
chr2_-_177925604 1.16 ENSMUST00000108934.2
ENSMUST00000081529.4
RIKEN cDNA C330013J21 gene
chr11_+_120491840 1.15 ENSMUST00000026899.3
solute carrier family 25 (mitochondrial carrier, dicarboxylate transporter), member 10
chr7_-_80402743 1.14 ENSMUST00000122232.1
furin (paired basic amino acid cleaving enzyme)
chr11_+_119022962 1.06 ENSMUST00000026662.7
chromobox 2
chr9_+_92457369 1.05 ENSMUST00000034941.7
phospholipid scramblase 4
chr4_-_82505749 0.92 ENSMUST00000107245.2
ENSMUST00000107246.1
nuclear factor I/B
chrX_-_16817339 0.90 ENSMUST00000040820.6
monoamine oxidase B
chr6_-_144209471 0.86 ENSMUST00000038815.7
SRY-box containing gene 5
chr5_-_66451629 0.85 ENSMUST00000160063.1
amyloid beta (A4) precursor protein-binding, family B, member 2
chr6_-_144209448 0.80 ENSMUST00000077160.5
SRY-box containing gene 5
chr15_+_99579054 0.79 ENSMUST00000023752.4
aquaporin 2
chr9_-_29963112 0.78 ENSMUST00000075069.4
neurotrimin
chr14_-_16575456 0.77 ENSMUST00000063750.6
retinoic acid receptor, beta
chr12_+_98920567 0.77 ENSMUST00000085109.3
ENSMUST00000079146.6
tetratricopeptide repeat domain 8
chr6_-_144209558 0.77 ENSMUST00000111749.1
ENSMUST00000170367.2
SRY-box containing gene 5
chrX_+_139684980 0.76 ENSMUST00000096313.3
TBC1 domain family, member 8B
chr16_+_92058270 0.74 ENSMUST00000047429.8
ENSMUST00000113975.2
mitochondrial ribosomal protein S6
solute carrier family 5 (inositol transporters), member 3
chr16_-_55838827 0.72 ENSMUST00000096026.2
ENSMUST00000036273.6
ENSMUST00000114457.1
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta
chr11_-_77725281 0.71 ENSMUST00000078623.4
crystallin, beta A1
chr10_+_21993890 0.70 ENSMUST00000092673.4
serum/glucocorticoid regulated kinase 1
chr13_-_113180897 0.70 ENSMUST00000038212.7
granzyme K
chr18_+_36559972 0.69 ENSMUST00000134146.1
ankyrin repeat and KH domain containing 1
chr9_-_13446753 0.69 ENSMUST00000167906.2
predicted gene, 17571
chr19_-_5845471 0.66 ENSMUST00000174287.1
ENSMUST00000173672.1
nuclear paraspeckle assembly transcript 1 (non-protein coding)
chr13_+_73626886 0.63 ENSMUST00000022104.7
telomerase reverse transcriptase
chr4_-_138396438 0.63 ENSMUST00000105032.2
family with sequence similarity 43, member B
chr11_+_102836296 0.63 ENSMUST00000021302.8
ENSMUST00000107072.1
HIG1 domain family, member 1B
chrX_-_155216338 0.59 ENSMUST00000112551.3
spermidine/spermine N1-acetyl transferase 1
chr10_+_21994666 0.58 ENSMUST00000020145.5
serum/glucocorticoid regulated kinase 1
chr5_-_66618636 0.57 ENSMUST00000162382.1
ENSMUST00000160870.1
ENSMUST00000087256.5
ENSMUST00000160103.1
ENSMUST00000162349.1
amyloid beta (A4) precursor protein-binding, family B, member 2
chr6_-_142964404 0.56 ENSMUST00000032421.3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr16_+_84774123 0.55 ENSMUST00000114195.1
junction adhesion molecule 2
chr6_+_73248382 0.55 ENSMUST00000064740.6
succinate-CoA ligase, GDP-forming, alpha subunit
chr16_-_16600533 0.55 ENSMUST00000159542.1
FYVE, RhoGEF and PH domain containing 4
chr19_+_20405280 0.54 ENSMUST00000179640.1
RIKEN cDNA 1500015L24 gene
chr7_+_6371364 0.51 ENSMUST00000086323.4
ENSMUST00000108559.2
zinc finger protein 78
chrX_-_155216444 0.50 ENSMUST00000026318.8
spermidine/spermine N1-acetyl transferase 1
chr10_-_29535857 0.50 ENSMUST00000092623.3
R-spondin 3 homolog (Xenopus laevis)
chr13_+_73330982 0.48 ENSMUST00000022098.8
mitochondrial ribosomal protein L36
chr9_+_7764041 0.47 ENSMUST00000052865.9
transmembrane protein 123
chr14_+_63046988 0.47 ENSMUST00000067990.1
ENSMUST00000111203.1
defensin beta 42
chr5_-_66618752 0.47 ENSMUST00000162366.1
amyloid beta (A4) precursor protein-binding, family B, member 2
chr11_-_111800870 0.46 ENSMUST00000124855.1
predicted gene 11674
chr6_-_101377897 0.45 ENSMUST00000075994.6
PDZ domain containing RING finger 3
chr7_+_56239743 0.40 ENSMUST00000032633.5
ENSMUST00000156886.1
oculocutaneous albinism II
chr13_+_120154627 0.39 ENSMUST00000179071.1
predicted gene, 20767
chr5_-_66618772 0.39 ENSMUST00000162994.1
ENSMUST00000159512.1
ENSMUST00000159786.1
amyloid beta (A4) precursor protein-binding, family B, member 2
chr9_-_105521147 0.38 ENSMUST00000176770.1
ENSMUST00000085133.6
ATPase, Ca++-sequestering
chr17_+_43389436 0.38 ENSMUST00000113599.1
G protein-coupled receptor 116
chr13_-_119912752 0.37 ENSMUST00000179502.1
predicted gene, 21761
chr2_+_172549581 0.37 ENSMUST00000030391.2
transcription factor AP-2, gamma
chr3_+_102010138 0.36 ENSMUST00000066187.4
nescient helix loop helix 2
chr18_+_61275002 0.36 ENSMUST00000135688.1
phosphodiesterase 6A, cGMP-specific, rod, alpha
chr2_+_158192009 0.35 ENSMUST00000109506.1
RIKEN cDNA 1700060C20 gene
chr3_-_70807284 0.35 ENSMUST00000180497.1
predicted gene 6634
chr6_-_42461017 0.34 ENSMUST00000090156.1
olfactory receptor 458
chr13_+_120317567 0.32 ENSMUST00000178349.1
2-cell-stage, variable group, member 3
chr14_-_23803304 0.31 ENSMUST00000179836.1
ENSMUST00000172099.2
ENSMUST00000065788.8
ENSMUST00000179097.1
ENSMUST00000177634.1
ENSMUST00000074983.6
ENSMUST00000163322.2
ENSMUST00000100831.4
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr5_-_14978935 0.30 ENSMUST00000096953.4
predicted gene 10354
chr5_-_26022916 0.29 ENSMUST00000072286.6
predicted gene 5862
chr5_+_91027457 0.27 ENSMUST00000041516.8
epithelial mitogen
chr17_+_87107621 0.26 ENSMUST00000041369.6
suppressor of cytokine signaling 5
chr5_-_26058581 0.25 ENSMUST00000095004.3
predicted gene 7347
chr5_-_26039506 0.24 ENSMUST00000079447.2
spermatogenesis associated glutamate (E)-rich protein 4a
chr5_-_26105362 0.23 ENSMUST00000063524.2
RIKEN cDNA 5031410I06 gene
chr19_-_10525201 0.23 ENSMUST00000025570.6
succinate dehydrogenase complex assembly factor 2
chr7_+_6474088 0.23 ENSMUST00000056144.5
olfactory receptor 1346
chr18_+_36560581 0.22 ENSMUST00000155329.2
ankyrin repeat and KH domain containing 1
chr16_+_27389911 0.22 ENSMUST00000143823.1
coiled-coil domain containing 50
chr16_+_84774361 0.22 ENSMUST00000098407.2
junction adhesion molecule 2
chr5_-_26121421 0.22 ENSMUST00000088236.3
predicted gene 10220
chr8_+_125730005 0.21 ENSMUST00000143504.1
nucleoside-triphosphatase, cancer-related
chr11_+_23152135 0.21 ENSMUST00000141678.1
RIKEN cDNA 1700061J23 gene
chr5_-_25954344 0.21 ENSMUST00000162387.4
predicted gene, 21671
chr7_+_141078188 0.21 ENSMUST00000106039.2
plakophilin 3
chr7_-_81493725 0.20 ENSMUST00000119121.1
adaptor-related protein complex 3, beta 2 subunit
chr10_+_112165676 0.19 ENSMUST00000170013.1
calcyphosphine 2
chr2_+_125136692 0.19 ENSMUST00000099452.2
cortexin 2
chr5_-_25926215 0.18 ENSMUST00000167847.2
predicted gene, 21655
chr3_-_129755305 0.17 ENSMUST00000029653.2
epidermal growth factor
chr15_-_38078842 0.17 ENSMUST00000110336.2
ubiquitin protein ligase E3 component n-recognin 5
chr1_+_5588493 0.17 ENSMUST00000160777.1
ENSMUST00000027038.4
opioid receptor, kappa 1
chr3_+_92014583 0.17 ENSMUST00000047660.4
peptidoglycan recognition protein 3
chr5_-_26089291 0.15 ENSMUST00000094946.4
predicted gene 10471
chr11_+_54370625 0.14 ENSMUST00000094193.2
RIKEN cDNA 4930404A10 gene
chr3_-_40509737 0.14 ENSMUST00000179966.1
RIKEN cDNA 1700017G19 gene
chr11_-_118401826 0.13 ENSMUST00000106290.3
ENSMUST00000043722.3
lectin, galactoside-binding, soluble, 3 binding protein
chr15_+_5185700 0.13 ENSMUST00000081640.5
tetratricopeptide repeat domain 33
chr5_+_17373208 0.11 ENSMUST00000166086.1
predicted gene 3495
chr1_+_83159733 0.11 ENSMUST00000113436.1
ENSMUST00000065436.3
ENSMUST00000065403.6
dynein assembly factor with WDR repeat domains 1
chr3_-_145099024 0.08 ENSMUST00000040465.6
chloride channel calcium activated 5
chr10_+_86655939 0.08 ENSMUST00000171131.1
predicted gene 5174
chr14_+_8080315 0.06 ENSMUST00000023924.3
ribonuclease P 14 subunit
chr8_-_46124146 0.05 ENSMUST00000170416.1
sorting nexin 25
chr7_-_126625676 0.05 ENSMUST00000032961.3
nuclear protein transcription regulator 1
chr15_-_57265126 0.05 ENSMUST00000137764.1
ENSMUST00000022995.6
solute carrier family 22 (organic cation transporter), member 22
chr19_-_7039987 0.04 ENSMUST00000025918.7
stress-induced phosphoprotein 1
chr2_+_176831140 0.02 ENSMUST00000122218.2
ENSMUST00000126726.1
predicted gene 14408
chr7_-_141918481 0.01 ENSMUST00000151890.1
toll interacting protein
chr8_-_129131661 0.01 ENSMUST00000108743.1
predicted gene 10999
chr19_-_7711263 0.00 ENSMUST00000025666.7
solute carrier family 22 (organic anion transporter), member 19
chr9_+_99456243 0.00 ENSMUST00000163199.2
RIKEN cDNA 1600029I14 gene

Network of associatons between targets according to the STRING database.

First level regulatory network of Nfat5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.0 GO:0006710 androgen catabolic process(GO:0006710)
0.6 2.6 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.6 7.3 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.6 5.2 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.4 1.2 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.3 1.4 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.3 4.7 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.3 1.2 GO:0015744 succinate transport(GO:0015744)
0.3 1.1 GO:0090472 dibasic protein processing(GO:0090472)
0.3 2.4 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.3 1.6 GO:0060011 Sertoli cell proliferation(GO:0060011) prostate epithelial cord elongation(GO:0060523)
0.3 0.8 GO:0071462 cellular response to mercury ion(GO:0071288) cellular response to water stimulus(GO:0071462)
0.2 2.7 GO:0005513 detection of calcium ion(GO:0005513)
0.2 1.1 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.2 2.8 GO:0019530 taurine metabolic process(GO:0019530)
0.2 0.6 GO:1900369 negative regulation of RNA interference(GO:1900369) regulation of histone demethylase activity (H3-K4 specific)(GO:1904173)
0.2 2.3 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 0.9 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
0.1 1.2 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.1 5.6 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866)
0.1 0.7 GO:2000210 positive regulation of anoikis(GO:2000210)
0.1 0.4 GO:0032468 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071)
0.1 0.4 GO:0060598 dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis(GO:0060598)
0.1 1.3 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.1 0.7 GO:0015791 polyol transport(GO:0015791)
0.1 0.6 GO:0006105 succinate metabolic process(GO:0006105)
0.1 0.3 GO:1904305 negative regulation of gastro-intestinal system smooth muscle contraction(GO:1904305) negative regulation of small intestine smooth muscle contraction(GO:1904348)
0.1 0.8 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.1 0.2 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.1 0.5 GO:0030035 microspike assembly(GO:0030035)
0.1 0.2 GO:0007262 STAT protein import into nucleus(GO:0007262)
0.1 0.2 GO:1900045 negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.1 0.2 GO:0051710 regulation of cytolysis in other organism(GO:0051710) positive regulation of cytolysis in other organism(GO:0051714)
0.1 1.6 GO:0046325 negative regulation of glucose import(GO:0046325)
0.0 0.3 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.0 0.2 GO:0031635 adenylate cyclase-inhibiting opioid receptor signaling pathway(GO:0031635)
0.0 1.7 GO:0072348 sulfur compound transport(GO:0072348)
0.0 0.2 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.8 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 6.0 GO:0008654 phospholipid biosynthetic process(GO:0008654)
0.0 0.4 GO:0046037 GMP metabolic process(GO:0046037)
0.0 0.5 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.7 GO:0030575 nuclear body organization(GO:0030575)
0.0 1.3 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.5 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.3 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 1.4 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.4 GO:0042438 melanin biosynthetic process(GO:0042438)
0.0 2.3 GO:0030048 actin filament-based movement(GO:0030048)
0.0 0.4 GO:0007617 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.0 2.3 GO:0006694 steroid biosynthetic process(GO:0006694)
0.0 0.0 GO:0071718 sodium-independent icosanoid transport(GO:0071718)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.3 1.3 GO:0005610 laminin-5 complex(GO:0005610)
0.2 1.6 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.2 3.8 GO:0030061 mitochondrial crista(GO:0030061)
0.2 0.8 GO:0031310 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.1 2.7 GO:0031045 dense core granule(GO:0031045)
0.1 2.6 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 0.6 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.1 0.7 GO:0042382 paraspeckles(GO:0042382)
0.1 0.8 GO:0034464 BBSome(GO:0034464)
0.1 1.1 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.1 1.1 GO:0035102 PRC1 complex(GO:0035102)
0.1 0.4 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.1 1.6 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.2 GO:0005914 spot adherens junction(GO:0005914)
0.0 2.3 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 3.0 GO:0005811 lipid particle(GO:0005811)
0.0 0.3 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.6 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.7 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 1.2 GO:0016459 myosin complex(GO:0016459)
0.0 3.7 GO:0000139 Golgi membrane(GO:0000139)
0.0 2.4 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.0 1.2 GO:0032587 ruffle membrane(GO:0032587)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 5.2 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.9 4.7 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.7 2.7 GO:0030348 syntaxin-3 binding(GO:0030348)
0.7 2.6 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
0.6 1.7 GO:0030977 taurine binding(GO:0030977)
0.5 1.6 GO:0038052 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.4 1.2 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.3 2.3 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.3 6.0 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.3 1.1 GO:0019809 spermidine binding(GO:0019809)
0.2 3.0 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.2 7.3 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.2 0.6 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.2 1.6 GO:0031419 cobalamin binding(GO:0031419)
0.2 1.3 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1 2.8 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.1 1.4 GO:0070324 thyroid hormone receptor activity(GO:0004887) thyroid hormone binding(GO:0070324)
0.1 0.8 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.1 0.9 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 0.4 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
0.1 1.1 GO:0042609 CD4 receptor binding(GO:0042609)
0.1 0.6 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 1.2 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.1 0.3 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.1 1.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 1.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 0.7 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 2.6 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 0.6 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 2.3 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.8 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.2 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.2 GO:0016019 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745) peptidoglycan receptor activity(GO:0016019)
0.0 0.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.2 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.8 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.4 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 1.1 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.2 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 1.2 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.5 GO:0005109 frizzled binding(GO:0005109)
0.0 0.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 4.1 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 2.5 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.1 4.7 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 2.2 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.1 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.9 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 1.3 PID FOXO PATHWAY FoxO family signaling
0.0 0.8 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.6 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 1.2 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 1.1 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.4 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.2 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.8 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.2 3.0 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.2 2.7 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.2 2.3 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.1 6.0 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 1.5 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.1 4.7 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.1 2.4 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 1.7 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 1.1 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 0.8 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 1.1 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 1.2 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 1.6 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.6 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.9 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.6 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 1.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.3 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.4 REACTOME CGMP EFFECTS Genes involved in cGMP effects