Project

GSE58827: Dynamics of the Mouse Liver

Navigation
Downloads

Results for Nfil3_Tef

Z-value: 1.91

Motif logo

Transcription factors associated with Nfil3_Tef

Gene Symbol Gene ID Gene Info
ENSMUSG00000056749.7 nuclear factor, interleukin 3, regulated
ENSMUSG00000022389.8 thyrotroph embryonic factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nfil3mm10_v2_chr13_-_52981027_529810830.642.7e-05Click!
Tefmm10_v2_chr15_+_81811414_81811491-0.019.5e-01Click!

Activity profile of Nfil3_Tef motif

Sorted Z-values of Nfil3_Tef motif

Promoter Log-likelihood Transcript Gene Gene Info
chr14_+_65970804 18.51 ENSMUST00000138191.1
clusterin
chr14_+_65971049 18.27 ENSMUST00000128539.1
clusterin
chr5_-_92328068 17.34 ENSMUST00000113093.3
chemokine (C-X-C motif) ligand 9
chr14_+_65971164 16.55 ENSMUST00000144619.1
clusterin
chr14_+_65970610 14.82 ENSMUST00000127387.1
clusterin
chr4_-_60582152 11.95 ENSMUST00000098047.2
major urinary protein 10
chr6_-_119467210 11.85 ENSMUST00000118120.1
wingless-related MMTV integration site 5B
chr5_-_86926521 11.56 ENSMUST00000031183.2
UDP glucuronosyltransferase 2 family, polypeptide B1
chr8_-_93197799 11.50 ENSMUST00000034172.7
carboxylesterase 1D
chr9_-_78347140 10.60 ENSMUST00000034902.5
glutathione S-transferase, alpha 2 (Yc2)
chr16_+_22951072 10.12 ENSMUST00000023590.8
histidine-rich glycoprotein
chr14_-_37048957 10.04 ENSMUST00000022338.5
retinal G protein coupled receptor
chr8_-_93131271 9.96 ENSMUST00000034189.8
carboxylesterase 1C
chr9_-_78347162 9.72 ENSMUST00000129247.1
glutathione S-transferase, alpha 2 (Yc2)
chr2_+_102706356 9.68 ENSMUST00000123759.1
ENSMUST00000111212.1
ENSMUST00000005220.4
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr8_-_93079965 9.01 ENSMUST00000109582.1
carboxylesterase 1B
chr2_+_129800451 8.47 ENSMUST00000165413.2
ENSMUST00000166282.2
serine/threonine kinase 35
chr19_-_7802578 8.32 ENSMUST00000120522.1
ENSMUST00000065634.7
solute carrier family 22 (organic cation transporter), member 26
chr7_-_81706905 8.09 ENSMUST00000026922.7
homer homolog 2 (Drosophila)
chr5_-_147894804 8.01 ENSMUST00000118527.1
ENSMUST00000031655.3
ENSMUST00000138244.1
solute carrier family 46, member 3
chr14_+_41105359 7.92 ENSMUST00000047286.6
methionine adenosyltransferase I, alpha
chr7_+_119526269 7.72 ENSMUST00000066465.1
acyl-CoA synthetase medium-chain family member 5
chr14_-_18239053 7.71 ENSMUST00000090543.5
nuclear receptor subfamily 1, group D, member 2
chr3_-_129332713 7.56 ENSMUST00000029658.7
glutamyl aminopeptidase
chr17_+_43801823 7.54 ENSMUST00000044895.5
regulator of calcineurin 2
chr17_+_36942910 7.32 ENSMUST00000040498.5
ring finger protein 39
chr10_-_31445921 7.19 ENSMUST00000000305.5
tumor protein D52-like 1
chr11_-_43901187 7.12 ENSMUST00000067258.2
ENSMUST00000139906.1
adrenergic receptor, alpha 1b
chr11_+_78290841 6.75 ENSMUST00000046361.4
cDNA sequence BC030499
chr9_+_78230644 6.69 ENSMUST00000098537.3
glutathione S-transferase, alpha 1 (Ya)
chr17_+_36943025 6.54 ENSMUST00000173072.1
ring finger protein 39
chr19_+_23141183 6.39 ENSMUST00000036884.1
Kruppel-like factor 9
chr3_-_113574758 6.37 ENSMUST00000106540.1
amylase 1, salivary
chr4_+_85205417 6.26 ENSMUST00000030212.8
ENSMUST00000107189.1
ENSMUST00000107184.1
SH3-domain GRB2-like 2
chr12_-_80968075 6.22 ENSMUST00000095572.4
solute carrier family 10 (sodium/bile acid cotransporter family), member 1
chr9_+_78289923 6.21 ENSMUST00000119823.1
ENSMUST00000121273.1
predicted gene 10639
chr7_+_26307190 5.96 ENSMUST00000098657.3
cytochrome P450, family 2, subfamily a, polypeptide 4
chr4_-_134853294 5.94 ENSMUST00000030628.8
transmembrane protein 57
chr2_-_25470031 5.94 ENSMUST00000114251.1
prostaglandin D2 synthase (brain)
chr6_+_21986887 5.92 ENSMUST00000151315.1
cadherin-like and PC-esterase domain containing 1
chr19_+_31868754 5.90 ENSMUST00000075838.5
APOBEC1 complementation factor
chr11_+_115462464 5.74 ENSMUST00000106532.3
ENSMUST00000092445.5
ENSMUST00000153466.1
solute carrier family 16 (monocarboxylic acid transporters), member 5
chr2_-_25469742 5.62 ENSMUST00000114259.2
ENSMUST00000015234.6
prostaglandin D2 synthase (brain)
chr19_-_11081088 5.57 ENSMUST00000025636.6
membrane-spanning 4-domains, subfamily A, member 8A
chr11_-_69685537 5.49 ENSMUST00000018896.7
tumor necrosis factor (ligand) superfamily, member 13
chr11_-_78422217 5.38 ENSMUST00000001122.5
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr5_+_90460889 5.15 ENSMUST00000031314.8
albumin
chr8_-_91134027 5.08 ENSMUST00000125257.1
thymoma viral proto-oncogene 1 interacting protein
chr15_+_7129557 5.00 ENSMUST00000067190.5
ENSMUST00000164529.1
leukemia inhibitory factor receptor
chr7_+_144175513 4.82 ENSMUST00000105900.1
SH3/ankyrin domain gene 2
chr2_+_104027721 4.80 ENSMUST00000028603.3
F-box protein 3
chr11_-_106216318 4.73 ENSMUST00000002043.3
coiled-coil domain containing 47
chr8_-_91133942 4.73 ENSMUST00000120213.1
ENSMUST00000109609.2
thymoma viral proto-oncogene 1 interacting protein
chr6_+_133105239 4.65 ENSMUST00000100864.4
RIKEN cDNA 2700089E24 gene
chr14_-_45388772 4.64 ENSMUST00000046191.7
glucosamine-phosphate N-acetyltransferase 1
chr6_-_142322978 4.55 ENSMUST00000081380.3
solute carrier organic anion transporter family, member 1a5
chrX_+_10717390 4.45 ENSMUST00000115524.1
ENSMUST00000008179.6
Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish))
chr1_-_140183404 4.44 ENSMUST00000066859.6
ENSMUST00000111976.2
complement component factor h
chr1_-_140183283 4.39 ENSMUST00000111977.1
complement component factor h
chrX_+_10717451 4.37 ENSMUST00000156321.1
Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish))
chr8_-_123158268 4.31 ENSMUST00000000755.7
sulfotransferase family 5A, member 1
chr8_-_123158229 4.26 ENSMUST00000137998.1
sulfotransferase family 5A, member 1
chr3_-_104366613 4.20 ENSMUST00000056145.2
predicted gene 5546
chr16_+_3884657 4.14 ENSMUST00000176625.1
N(alpha)-acetyltransferase 60, NatF catalytic subunit
chr11_+_83703991 4.10 ENSMUST00000092836.5
WAP four-disulfide core domain 17
chr11_+_94328242 3.92 ENSMUST00000021227.5
ankyrin repeat domain 40
chr4_+_47208005 3.88 ENSMUST00000082303.6
ENSMUST00000102917.4
collagen, type XV, alpha 1
chr4_-_104876383 3.86 ENSMUST00000064873.8
ENSMUST00000106808.3
ENSMUST00000048947.8
complement component 8, alpha polypeptide
chr16_+_3884629 3.83 ENSMUST00000176233.1
predicted gene 20695
chr7_+_26173411 3.79 ENSMUST00000082214.4
cytochrome P450, family 2, subfamily b, polypeptide 9
chr15_-_77399086 3.78 ENSMUST00000175919.1
ENSMUST00000176074.1
apolipoprotein L 7a
chr19_-_34747289 3.69 ENSMUST00000009522.3
solute carrier family 16 (monocarboxylic acid transporters), member 12
chr5_-_89457763 3.60 ENSMUST00000049209.8
group specific component
chr9_+_121366958 3.58 ENSMUST00000045903.6
trafficking protein, kinesin binding 1
chr15_-_37007382 3.48 ENSMUST00000078976.7
zinc finger protein 706
chr11_+_94327984 3.42 ENSMUST00000107818.2
ENSMUST00000051221.6
ankyrin repeat domain 40
chr2_+_104027823 3.38 ENSMUST00000111135.1
ENSMUST00000111136.1
ENSMUST00000102565.3
F-box protein 3
chr19_-_38124801 3.34 ENSMUST00000112335.2
retinol binding protein 4, plasma
chr19_+_32619997 3.30 ENSMUST00000025833.6
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr11_+_83709015 3.27 ENSMUST00000001009.7
WAP four-disulfide core domain 18
chr14_+_48120841 3.25 ENSMUST00000073150.4
pellino 2
chr3_+_96245530 3.19 ENSMUST00000074976.6
histone cluster 2, H2aa1
chr19_-_38125258 3.15 ENSMUST00000025951.6
retinol binding protein 4, plasma
chr10_+_127421124 3.13 ENSMUST00000170336.1
R3H domain containing 2
chr3_+_30792876 3.11 ENSMUST00000029256.7
SEC62 homolog (S. cerevisiae)
chr3_-_98753465 3.09 ENSMUST00000094050.4
ENSMUST00000090743.6
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3
chr11_+_60728398 3.08 ENSMUST00000018743.4
mitochondrial elongation factor 2
chr14_+_78849171 3.08 ENSMUST00000040990.5
von Willebrand factor A domain containing 8
chr1_+_21218575 3.06 ENSMUST00000027065.5
ENSMUST00000027064.7
transmembrane protein 14A
chr1_-_58586191 3.05 ENSMUST00000038372.7
ENSMUST00000097724.3
ENSMUST00000161000.1
ENSMUST00000161600.1
family with sequence similarity 126, member B
chr10_-_78464969 3.04 ENSMUST00000041616.8
pyridoxal (pyridoxine, vitamin B6) kinase
chrX_+_57212110 3.02 ENSMUST00000033466.1
CD40 ligand
chr5_-_88526496 3.01 ENSMUST00000164073.1
immunoglobulin joining chain
chr4_+_43493345 2.99 ENSMUST00000030181.5
ENSMUST00000107922.2
coiled-coil domain containing 107
chr3_-_96240317 2.99 ENSMUST00000078756.5
histone cluster 2, H2aa2
chr6_+_124493101 2.89 ENSMUST00000049124.9
complement component 1, r subcomponent-like
chr10_+_127421208 2.84 ENSMUST00000168780.1
R3H domain containing 2
chr15_+_37007523 2.73 ENSMUST00000181411.1
predicted gene, 26766
chr3_+_60031754 2.73 ENSMUST00000029325.3
arylacetamide deacetylase (esterase)
chr16_-_11909398 2.69 ENSMUST00000127972.1
ENSMUST00000121750.1
ENSMUST00000096272.4
ENSMUST00000073371.6
calcineurin-like phosphoesterase domain containing 1
chr5_-_130024280 2.68 ENSMUST00000161640.1
ENSMUST00000161884.1
ENSMUST00000161094.1
argininosuccinate lyase
chr15_+_44619551 2.67 ENSMUST00000022964.7
estrogen receptor-binding fragment-associated gene 9
chr15_+_68928414 2.66 ENSMUST00000022954.6
KH domain containing, RNA binding, signal transduction associated 3
chr10_-_78464853 2.63 ENSMUST00000105385.1
pyridoxal (pyridoxine, vitamin B6) kinase
chr8_+_45628176 2.59 ENSMUST00000130850.1
sorbin and SH3 domain containing 2
chr6_+_17463749 2.57 ENSMUST00000115443.1
met proto-oncogene
chr13_-_52981027 2.57 ENSMUST00000071065.7
nuclear factor, interleukin 3, regulated
chr15_-_33687840 2.56 ENSMUST00000042021.3
testis-specific protein, Y-encoded-like 5
chr2_+_116900152 2.56 ENSMUST00000126467.1
ENSMUST00000128305.1
ENSMUST00000155323.1
RIKEN cDNA D330050G23 gene
chr5_+_135009152 2.56 ENSMUST00000111216.1
ENSMUST00000046999.8
abhydrolase domain containing 11
chr7_+_44676965 2.56 ENSMUST00000094460.1
RIKEN cDNA 2310016G11 gene
chr14_-_18893376 2.54 ENSMUST00000151926.1
ubiquitin-conjugating enzyme E2E 2
chr17_-_73950172 2.49 ENSMUST00000024866.4
xanthine dehydrogenase
chr12_-_81379464 2.44 ENSMUST00000062182.7
predicted gene 4787
chr11_-_73326472 2.38 ENSMUST00000155630.2
aspartoacylase
chr9_+_78191966 2.36 ENSMUST00000034903.5
glutathione S-transferase, alpha 4
chrX_-_162565514 2.36 ENSMUST00000154424.1
RALBP1 associated Eps domain containing protein 2
chr8_+_46490968 2.35 ENSMUST00000110372.1
ENSMUST00000130563.1
acyl-CoA synthetase long-chain family member 1
chr13_+_24943144 2.35 ENSMUST00000021773.5
glycosylphosphatidylinositol specific phospholipase D1
chrX_+_36328353 2.32 ENSMUST00000016383.3
LON peptidase N-terminal domain and ring finger 3
chr8_-_93363676 2.26 ENSMUST00000145041.1
carboxylesterase 1H
chr2_-_60284292 2.25 ENSMUST00000028356.8
ENSMUST00000074606.4
CD302 antigen
chr3_-_138143352 2.25 ENSMUST00000098580.2
microsomal triglyceride transfer protein
chr5_-_52669677 2.23 ENSMUST00000031069.6
Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase
chr2_+_177508570 2.19 ENSMUST00000108940.2
predicted gene 14403
chr2_-_86347764 2.18 ENSMUST00000099894.2
olfactory receptor 1055
chr16_+_56477838 2.18 ENSMUST00000048471.7
ENSMUST00000096013.3
ENSMUST00000096012.3
ENSMUST00000171000.1
ABI gene family, member 3 (NESH) binding protein
chr5_-_5514730 2.14 ENSMUST00000115445.1
ENSMUST00000179804.1
ENSMUST00000125110.1
ENSMUST00000115446.1
claudin 12
chr10_+_69219357 2.14 ENSMUST00000172261.1
Rho-related BTB domain containing 1
chr10_-_44004846 2.14 ENSMUST00000020017.8
absent in melanoma 1
chr9_-_71163224 2.11 ENSMUST00000074465.2
aquaporin 9
chr1_+_10993452 2.09 ENSMUST00000027056.5
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr7_-_5805445 2.08 ENSMUST00000075085.6
vomeronasal 1 receptor 63
chr5_-_5514873 2.03 ENSMUST00000060947.7
claudin 12
chr9_+_94669876 2.03 ENSMUST00000033463.9
solute carrier family 9 (sodium/hydrogen exchanger), member 9
chr7_+_26757153 2.03 ENSMUST00000077855.6
cytochrome P450, family 2, subfamily b, polypeptide 19
chr13_+_63015167 2.03 ENSMUST00000021911.8
RIKEN cDNA 2010111I01 gene
chr10_+_23851454 2.00 ENSMUST00000020190.7
vanin 3
chr13_+_4574075 2.00 ENSMUST00000021628.3
aldo-keto reductase family 1, member C21
chr1_+_172698046 1.99 ENSMUST00000038495.3
C-reactive protein, pentraxin-related
chr2_+_118861954 1.98 ENSMUST00000028807.5
isovaleryl coenzyme A dehydrogenase
chr9_+_109931458 1.98 ENSMUST00000072772.5
ENSMUST00000035055.8
microtubule-associated protein 4
chr10_-_125308809 1.97 ENSMUST00000105257.2
solute carrier family 16 (monocarboxylic acid transporters), member 7
chr9_+_43744399 1.97 ENSMUST00000034510.7
poliovirus receptor-related 1
chr13_+_63014934 1.96 ENSMUST00000091560.4
RIKEN cDNA 2010111I01 gene
chr2_-_156004147 1.94 ENSMUST00000156993.1
ENSMUST00000141437.1
RIKEN cDNA 6430550D23 gene
chr17_+_26715644 1.90 ENSMUST00000062519.7
ENSMUST00000144221.1
ENSMUST00000142539.1
ENSMUST00000151681.1
CREB3 regulatory factor
chr12_+_21316385 1.88 ENSMUST00000076813.6
isoamyl acetate-hydrolyzing esterase 1 homolog (S. cerevisiae)
chr7_-_5413145 1.88 ENSMUST00000108569.2
vomeronasal 1 receptor 58
chr10_+_53337686 1.87 ENSMUST00000046221.6
ENSMUST00000163319.1
phospholamban
chr16_-_16527364 1.86 ENSMUST00000069284.7
FYVE, RhoGEF and PH domain containing 4
chr17_-_45592569 1.83 ENSMUST00000163492.1
solute carrier family 29 (nucleoside transporters), member 1
chr13_+_16011851 1.82 ENSMUST00000042603.6
inhibin beta-A
chr4_+_19575139 1.81 ENSMUST00000108253.1
ENSMUST00000029888.3
regulator of microtubule dynamics 1
chr11_-_6444352 1.74 ENSMUST00000093346.5
ENSMUST00000109737.2
H2A histone family, member V
chr17_+_8283762 1.69 ENSMUST00000155364.1
ENSMUST00000046754.8
ENSMUST00000124023.1
mitochondrial pyruvate carrier 1
chr3_+_89459118 1.69 ENSMUST00000029564.5
phosphomevalonate kinase
chr8_+_25808474 1.67 ENSMUST00000033979.4
steroidogenic acute regulatory protein
chr1_-_179803625 1.65 ENSMUST00000027768.7
AT hook containing transcription factor 1
chr15_-_93336800 1.65 ENSMUST00000080299.6
YY1 associated factor 2
chr3_-_88762244 1.65 ENSMUST00000183267.1
synaptotagmin XI
chr3_+_138443085 1.64 ENSMUST00000005964.2
alcohol dehydrogenase 5 (class III), chi polypeptide
chr16_+_45093611 1.64 ENSMUST00000099498.2
coiled-coil domain containing 80
chr7_+_29238434 1.63 ENSMUST00000108237.1
Yip1 interacting factor homolog B (S. cerevisiae)
chr4_-_119538769 1.60 ENSMUST00000079611.6
expressed sequence AA415398
chr4_+_42735545 1.59 ENSMUST00000068158.3
RIKEN cDNA 4930578G10 gene
chr7_+_26061495 1.58 ENSMUST00000005669.7
cytochrome P450, family 2, subfamily b, polypeptide 13
chr4_-_41774097 1.54 ENSMUST00000108036.1
ENSMUST00000173865.1
ENSMUST00000108037.2
ENSMUST00000108032.2
chemokine (C-C motif) ligand 27A
chr12_+_37241729 1.53 ENSMUST00000160768.1
alkylglycerol monooxygenase
chr7_-_26686437 1.51 ENSMUST00000077356.6
cytochrome P450, family 2, subfamily b, polypeptide 23
chr3_+_114904062 1.50 ENSMUST00000081752.6
olfactomedin 3
chr15_+_41830921 1.50 ENSMUST00000166917.1
oxidation resistance 1
chr12_+_37241633 1.47 ENSMUST00000049874.7
alkylglycerol monooxygenase
chr12_+_37242030 1.45 ENSMUST00000160390.1
alkylglycerol monooxygenase
chr6_-_55681257 1.43 ENSMUST00000044767.8
neurogenic differentiation 6
chr19_-_8723356 1.43 ENSMUST00000170157.1
solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
chr7_+_29238323 1.39 ENSMUST00000108238.1
ENSMUST00000032809.3
ENSMUST00000138128.1
Yip1 interacting factor homolog B (S. cerevisiae)
chr9_+_109931863 1.34 ENSMUST00000165876.1
microtubule-associated protein 4
chr4_+_101419696 1.33 ENSMUST00000131397.1
ENSMUST00000133055.1
adenylate kinase 4
chr7_-_127393604 1.32 ENSMUST00000165495.1
ENSMUST00000106303.2
ENSMUST00000074249.6
RIKEN cDNA E430018J23 gene
chr8_+_22060712 1.31 ENSMUST00000072572.6
ENSMUST00000110737.2
ENSMUST00000131624.1
asparagine-linked glycosylation 11 (alpha-1,2-mannosyltransferase)
chr8_-_41041828 1.31 ENSMUST00000051379.7
mitochondrial tumor suppressor 1
chr5_-_30196418 1.31 ENSMUST00000125367.1
G protein-coupled receptor 113
chr13_-_67451585 1.28 ENSMUST00000057241.8
ENSMUST00000075255.5
zinc finger protein 874a
chr8_-_34146974 1.26 ENSMUST00000033910.8
leptin receptor overlapping transcript-like 1
chr6_-_129623840 1.26 ENSMUST00000095412.4
ENSMUST00000168919.1
killer cell lectin-like receptor subfamily K, member 1
chr6_+_106118924 1.25 ENSMUST00000079416.5
contactin 4
chr17_-_45592485 1.19 ENSMUST00000166119.1
solute carrier family 29 (nucleoside transporters), member 1
chr4_+_42735912 1.19 ENSMUST00000107984.1
RIKEN cDNA 4930578G10 gene
chr14_+_51411001 1.18 ENSMUST00000022438.5
ENSMUST00000163019.1
ENSMUST00000159674.1
vomeronasal 2, receptor 88
chrM_+_7005 1.18 ENSMUST00000082405.1
mitochondrially encoded cytochrome c oxidase II
chr4_-_150003130 1.14 ENSMUST00000084117.6
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr5_-_88676135 1.13 ENSMUST00000078945.5
G-rich RNA sequence binding factor 1
chr15_-_38078842 1.12 ENSMUST00000110336.2
ubiquitin protein ligase E3 component n-recognin 5
chr6_+_121183667 1.11 ENSMUST00000118234.1
ENSMUST00000088561.3
ENSMUST00000137432.1
ENSMUST00000120066.1
peroxisomal biogenesis factor 26
chr11_+_21091291 1.11 ENSMUST00000093290.5
pellino 1
chr2_-_12419456 1.10 ENSMUST00000154899.1
ENSMUST00000028105.6
family with sequence similarity 188, member A
chr4_+_128846163 1.10 ENSMUST00000138291.1
predicted gene 12968
chr3_-_30793549 1.09 ENSMUST00000180833.1
RIKEN cDNA 4933429H19 gene
chr7_+_100607410 1.08 ENSMUST00000107048.1
ENSMUST00000032946.3
RAB6A, member RAS oncogene family

Network of associatons between targets according to the STRING database.

First level regulatory network of Nfil3_Tef

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
11.4 68.2 GO:1902998 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
3.9 11.6 GO:0018879 biphenyl metabolic process(GO:0018879)
3.8 11.5 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
3.4 10.1 GO:0034395 regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
2.4 7.1 GO:0001982 baroreceptor response to decreased systemic arterial blood pressure(GO:0001982)
2.3 11.6 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
2.0 7.9 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
1.9 5.7 GO:0042823 pyridoxal phosphate biosynthetic process(GO:0042823)
1.8 5.5 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
1.7 5.2 GO:0051659 maintenance of mitochondrion location(GO:0051659)
1.6 6.5 GO:0048807 female genitalia morphogenesis(GO:0048807)
1.4 9.7 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
1.3 37.8 GO:0035634 response to stilbenoid(GO:0035634)
1.3 7.5 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
1.2 11.2 GO:0045919 positive regulation of cytolysis(GO:0045919)
1.2 3.7 GO:0015881 creatine transport(GO:0015881)
1.1 7.6 GO:0002003 angiotensin maturation(GO:0002003)
1.0 3.0 GO:2001200 positive regulation of dendritic cell differentiation(GO:2001200)
1.0 5.0 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.9 4.6 GO:0006041 glucosamine metabolic process(GO:0006041) UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.9 3.7 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.9 10.0 GO:0018298 protein-chromophore linkage(GO:0018298)
0.9 2.7 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450)
0.8 4.2 GO:0051012 microtubule sliding(GO:0051012)
0.8 5.8 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.7 3.3 GO:0000103 sulfate assimilation(GO:0000103)
0.6 17.3 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.6 2.6 GO:0046294 formaldehyde catabolic process(GO:0046294)
0.6 8.3 GO:0015747 urate transport(GO:0015747)
0.6 4.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.6 5.9 GO:0016554 cytidine to uridine editing(GO:0016554)
0.6 2.2 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.5 1.6 GO:1990927 calcium ion regulated lysosome exocytosis(GO:1990927)
0.5 2.1 GO:0015855 nucleobase transport(GO:0015851) pyrimidine nucleobase transport(GO:0015855)
0.5 1.5 GO:0071677 positive regulation of mononuclear cell migration(GO:0071677)
0.5 2.5 GO:0009115 xanthine catabolic process(GO:0009115)
0.5 2.7 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.4 11.1 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.4 3.0 GO:0015862 uridine transport(GO:0015862)
0.4 1.7 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.4 1.3 GO:0002223 stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.4 1.3 GO:0033577 protein glycosylation in endoplasmic reticulum(GO:0033577)
0.4 8.8 GO:0035584 calcium-mediated signaling using intracellular calcium source(GO:0035584)
0.4 7.5 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.4 2.4 GO:0006083 acetate metabolic process(GO:0006083)
0.4 4.4 GO:0008063 Toll signaling pathway(GO:0008063)
0.4 4.7 GO:0006983 ER overload response(GO:0006983)
0.4 2.6 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.4 1.8 GO:0060279 positive regulation of ovulation(GO:0060279)
0.3 1.7 GO:1904253 positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.3 2.0 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.3 7.7 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.3 1.9 GO:1900170 prolactin signaling pathway(GO:0038161) negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.3 2.5 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.3 2.2 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.3 0.9 GO:0046333 octopamine biosynthetic process(GO:0006589) octopamine metabolic process(GO:0046333)
0.3 1.4 GO:0015820 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.3 3.1 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.3 2.2 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.3 4.4 GO:0046485 ether lipid metabolic process(GO:0046485)
0.3 8.8 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
0.3 3.9 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.3 13.4 GO:0008333 endosome to lysosome transport(GO:0008333)
0.3 3.5 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.2 2.3 GO:0044539 long-chain fatty acid import(GO:0044539)
0.2 0.7 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.2 0.7 GO:0001543 ovarian follicle rupture(GO:0001543)
0.2 4.0 GO:0042359 vitamin D metabolic process(GO:0042359)
0.2 0.9 GO:0060161 positive regulation of dopamine receptor signaling pathway(GO:0060161)
0.2 1.1 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.2 2.1 GO:0086023 adrenergic receptor signaling pathway involved in heart process(GO:0086023)
0.2 1.9 GO:0030035 microspike assembly(GO:0030035)
0.2 0.6 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.2 2.0 GO:0006551 leucine metabolic process(GO:0006551)
0.2 0.6 GO:0042275 error-free postreplication DNA repair(GO:0042275)
0.2 3.4 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.2 0.6 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.2 2.0 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.2 0.5 GO:0071726 response to diacyl bacterial lipopeptide(GO:0071724) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to diacyl bacterial lipopeptide(GO:0071726) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.2 11.9 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.1 1.5 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 4.8 GO:0071625 vocalization behavior(GO:0071625)
0.1 0.4 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.1 1.6 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.1 4.2 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.1 1.1 GO:0015919 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.1 0.7 GO:0070120 ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.1 0.6 GO:0016553 base conversion or substitution editing(GO:0016553)
0.1 1.2 GO:0060373 regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371) regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.1 1.6 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.1 0.8 GO:0070294 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.1 0.3 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 4.0 GO:0043171 peptide catabolic process(GO:0043171)
0.1 7.7 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.1 2.0 GO:0006767 water-soluble vitamin metabolic process(GO:0006767)
0.1 0.5 GO:0048840 otolith development(GO:0048840)
0.1 2.6 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.1 2.9 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 8.6 GO:0006342 chromatin silencing(GO:0006342)
0.1 0.6 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.1 2.6 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.1 1.6 GO:0046033 AMP metabolic process(GO:0046033)
0.1 1.0 GO:0052695 uronic acid metabolic process(GO:0006063) glucuronate metabolic process(GO:0019585) cellular glucuronidation(GO:0052695)
0.1 1.4 GO:0021542 dentate gyrus development(GO:0021542)
0.1 1.8 GO:0048240 sperm capacitation(GO:0048240)
0.1 0.5 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 2.7 GO:0033120 positive regulation of RNA splicing(GO:0033120)
0.1 0.3 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.3 GO:0001575 globoside metabolic process(GO:0001575)
0.0 0.5 GO:0002674 negative regulation of acute inflammatory response(GO:0002674)
0.0 0.1 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
0.0 0.2 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 1.3 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.0 6.4 GO:0016052 carbohydrate catabolic process(GO:0016052)
0.0 2.1 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.1 GO:0046459 short-chain fatty acid metabolic process(GO:0046459)
0.0 2.3 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.8 GO:1900037 regulation of cellular response to hypoxia(GO:1900037)
0.0 0.7 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 5.4 GO:0098656 anion transmembrane transport(GO:0098656)
0.0 5.6 GO:0046330 positive regulation of JNK cascade(GO:0046330)
0.0 0.3 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.7 GO:0032402 melanosome transport(GO:0032402)
0.0 0.8 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.3 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.0 0.1 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0 3.1 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 1.4 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.8 GO:0031424 keratinization(GO:0031424)
0.0 0.6 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 3.8 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.2 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.0 2.3 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 0.7 GO:0030539 male genitalia development(GO:0030539)
0.0 0.7 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.7 GO:0030488 tRNA methylation(GO:0030488)
0.0 1.5 GO:0030500 regulation of bone mineralization(GO:0030500)
0.0 1.2 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.0 0.0 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0 0.7 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 0.7 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.0 0.3 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.5 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 1.1 GO:0008033 tRNA processing(GO:0008033)
0.0 0.5 GO:1903078 positive regulation of protein localization to plasma membrane(GO:1903078)
0.0 0.4 GO:0000027 ribosomal large subunit assembly(GO:0000027)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
5.2 68.2 GO:0097418 neurofibrillary tangle(GO:0097418)
3.4 10.1 GO:0032010 phagolysosome(GO:0032010)
1.4 9.8 GO:0070695 FHF complex(GO:0070695)
1.0 5.9 GO:0045293 mRNA editing complex(GO:0045293)
0.7 7.6 GO:0031983 vesicle lumen(GO:0031983)
0.6 1.8 GO:0043512 inhibin A complex(GO:0043512)
0.5 1.1 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.5 4.8 GO:0005883 neurofilament(GO:0005883)
0.4 8.1 GO:0032426 stereocilium tip(GO:0032426)
0.4 3.9 GO:0005579 membrane attack complex(GO:0005579)
0.3 1.0 GO:0000814 ESCRT II complex(GO:0000814)
0.3 9.7 GO:0030673 axolemma(GO:0030673)
0.2 0.8 GO:0070552 BRISC complex(GO:0070552)
0.2 3.6 GO:1904115 axon cytoplasm(GO:1904115)
0.2 11.5 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.2 2.7 GO:0070852 cell body fiber(GO:0070852)
0.2 1.8 GO:0036128 CatSper complex(GO:0036128)
0.2 0.6 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.2 19.9 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.2 0.7 GO:0071942 XPC complex(GO:0071942)
0.2 0.7 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.2 0.8 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 1.6 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 3.8 GO:0005614 interstitial matrix(GO:0005614)
0.1 3.8 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 1.6 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 2.3 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 1.7 GO:0030061 mitochondrial crista(GO:0030061)
0.1 14.4 GO:0072562 blood microparticle(GO:0072562)
0.1 0.5 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 5.4 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 1.9 GO:0045277 respiratory chain complex IV(GO:0045277)
0.1 7.1 GO:0014704 intercalated disc(GO:0014704)
0.1 1.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 7.6 GO:0016363 nuclear matrix(GO:0016363)
0.1 0.6 GO:0071546 pi-body(GO:0071546)
0.1 4.2 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 4.0 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 3.2 GO:0009925 basal plasma membrane(GO:0009925)
0.1 1.7 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.1 3.9 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 0.7 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 9.9 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 4.6 GO:0030175 filopodium(GO:0030175)
0.0 12.4 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 4.9 GO:0031526 brush border membrane(GO:0031526)
0.0 0.7 GO:0005869 dynactin complex(GO:0005869)
0.0 0.7 GO:0030008 TRAPP complex(GO:0030008)
0.0 3.5 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 3.3 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 3.9 GO:0005604 collagen trimer(GO:0005581) basement membrane(GO:0005604)
0.0 0.8 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 12.4 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 4.9 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.9 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.5 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 3.0 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.7 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 7.0 GO:0005769 early endosome(GO:0005769)
0.0 0.7 GO:0005685 U1 snRNP(GO:0005685)
0.0 6.6 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 4.1 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 1.3 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.8 GO:0001533 cornified envelope(GO:0001533)
0.0 0.3 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.5 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.1 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.9 GO:0030667 secretory granule membrane(GO:0030667)
0.0 2.0 GO:0055037 recycling endosome(GO:0055037)
0.0 0.2 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.3 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 0.5 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.6 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 5.1 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.6 GO:0000786 nucleosome(GO:0000786)
0.0 0.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.4 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 3.0 GO:0030141 secretory granule(GO:0030141)
0.0 3.7 GO:0000139 Golgi membrane(GO:0000139)
0.0 31.8 GO:0070062 extracellular exosome(GO:0070062)
0.0 3.3 GO:0005874 microtubule(GO:0005874)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.8 11.5 GO:0004771 sterol esterase activity(GO:0004771)
3.5 17.3 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
2.9 11.6 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
2.8 68.2 GO:0051787 misfolded protein binding(GO:0051787)
2.0 8.1 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
2.0 2.0 GO:1902121 lithocholic acid binding(GO:1902121)
1.9 5.7 GO:0031403 lithium ion binding(GO:0031403)
1.8 7.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
1.7 5.0 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
1.6 9.7 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
1.5 4.4 GO:0050479 glyceryl-ether monooxygenase activity(GO:0050479)
1.3 8.8 GO:0001851 complement component C3b binding(GO:0001851)
1.3 7.5 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
1.3 10.0 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
1.2 3.7 GO:0005308 creatine transmembrane transporter activity(GO:0005308)
1.2 3.6 GO:1902271 D3 vitamins binding(GO:1902271)
1.1 7.7 GO:0003996 acyl-CoA ligase activity(GO:0003996)
1.0 29.4 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.9 3.7 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.9 6.2 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.8 2.4 GO:0019807 aspartoacylase activity(GO:0019807)
0.8 7.7 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.7 2.7 GO:0016842 amidine-lyase activity(GO:0016842)
0.6 2.6 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.6 6.4 GO:0031404 chloride ion binding(GO:0031404)
0.6 4.9 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.6 8.3 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.6 2.3 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
0.5 6.5 GO:0016918 retinal binding(GO:0016918)
0.5 1.6 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.5 11.5 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.5 2.5 GO:0016726 xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726)
0.4 1.3 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.4 2.5 GO:0042296 ISG15 transferase activity(GO:0042296)
0.4 2.1 GO:0015254 purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205) glycerol channel activity(GO:0015254)
0.4 5.4 GO:0015643 toxic substance binding(GO:0015643)
0.4 14.0 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.4 1.1 GO:0047936 glucose 1-dehydrogenase [NAD(P)] activity(GO:0047936)
0.4 1.4 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.3 12.6 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.3 1.6 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.3 1.9 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.3 0.9 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.3 0.9 GO:0018738 S-formylglutathione hydrolase activity(GO:0018738)
0.3 5.8 GO:0001848 complement binding(GO:0001848)
0.3 1.1 GO:0008147 structural constituent of bone(GO:0008147)
0.3 2.3 GO:0004630 phospholipase D activity(GO:0004630)
0.3 1.8 GO:0070699 type II activin receptor binding(GO:0070699)
0.3 4.1 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.2 6.2 GO:0004364 glutathione transferase activity(GO:0004364)
0.2 11.9 GO:0005109 frizzled binding(GO:0005109)
0.2 7.9 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.2 0.6 GO:0015229 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.2 3.6 GO:0050811 GABA receptor binding(GO:0050811)
0.2 8.2 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.2 0.7 GO:1903135 cupric ion binding(GO:1903135)
0.2 2.0 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.2 2.7 GO:0004806 triglyceride lipase activity(GO:0004806)
0.2 1.2 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.2 0.7 GO:0070052 collagen V binding(GO:0070052)
0.2 0.8 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.2 0.6 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.2 1.6 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.7 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.1 0.7 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.1 0.7 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.1 5.7 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.1 18.6 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.1 3.0 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.1 2.2 GO:0034185 apolipoprotein binding(GO:0034185)
0.1 0.3 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211)
0.1 0.9 GO:0031748 D1 dopamine receptor binding(GO:0031748)
0.1 3.3 GO:0070566 adenylyltransferase activity(GO:0070566)
0.1 2.0 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.1 0.7 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.1 1.1 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 0.5 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.1 0.5 GO:0071723 lipopeptide binding(GO:0071723)
0.1 0.5 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 0.4 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.1 0.3 GO:0048408 epidermal growth factor binding(GO:0048408)
0.1 1.9 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 7.4 GO:0003727 single-stranded RNA binding(GO:0003727)
0.1 0.6 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 18.3 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.1 1.3 GO:0042288 MHC class I protein binding(GO:0042288)
0.1 1.7 GO:0017127 cholesterol transporter activity(GO:0017127)
0.1 0.4 GO:0009374 biotin binding(GO:0009374)
0.1 9.0 GO:0008201 heparin binding(GO:0008201)
0.1 2.8 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.7 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 1.7 GO:0016776 phosphotransferase activity, phosphate group as acceptor(GO:0016776)
0.0 2.2 GO:0000049 tRNA binding(GO:0000049)
0.0 0.2 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 1.1 GO:0031489 myosin V binding(GO:0031489)
0.0 1.6 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 0.8 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.3 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.7 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.7 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 2.3 GO:0005549 odorant binding(GO:0005549)
0.0 0.3 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 1.4 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.9 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 8.8 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 0.7 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.2 GO:0046870 cadmium ion binding(GO:0046870)
0.0 15.3 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 0.7 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.4 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0 2.0 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 3.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 2.6 GO:0015293 symporter activity(GO:0015293)
0.0 0.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.7 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 1.2 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.0 0.3 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.7 GO:0030507 spectrin binding(GO:0030507)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 68.2 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.3 17.7 PID IL23 PATHWAY IL23-mediated signaling events
0.2 10.5 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 6.4 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.1 5.8 PID RHOA PATHWAY RhoA signaling pathway
0.1 5.2 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 5.5 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.1 2.0 PID NECTIN PATHWAY Nectin adhesion pathway
0.1 0.9 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.1 2.3 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 2.1 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 7.1 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.1 1.8 PID ALK1 PATHWAY ALK1 signaling events
0.0 2.0 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 3.4 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.6 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.4 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 2.1 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 6.1 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.3 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 1.3 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 2.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.2 PID GLYPICAN 1PATHWAY Glypican 1 network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 11.4 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
1.3 10.0 REACTOME OPSINS Genes involved in Opsins
0.7 78.4 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.7 29.4 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.7 8.8 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.5 7.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.3 4.4 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.3 7.9 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.3 5.8 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.3 4.6 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.3 11.8 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.3 5.8 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.3 3.3 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.2 7.8 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.2 2.5 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.2 2.1 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.2 11.1 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 2.3 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 1.3 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.1 6.3 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 4.2 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 2.0 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 2.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 4.3 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 7.7 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 1.0 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 0.7 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 3.0 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 0.5 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 1.7 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 1.6 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 2.6 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.1 0.7 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.1 2.0 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 3.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 0.6 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 5.5 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 1.1 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.7 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 8.3 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 1.0 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.5 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 6.5 REACTOME MRNA PROCESSING Genes involved in mRNA Processing
0.0 1.3 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.8 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 1.2 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.6 REACTOME GRB2 EVENTS IN ERBB2 SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.0 0.3 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.0 0.3 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.0 2.5 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 1.0 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 1.0 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.5 REACTOME AQUAPORIN MEDIATED TRANSPORT Genes involved in Aquaporin-mediated transport
0.0 0.8 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 2.4 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.7 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.4 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling