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GSE58827: Dynamics of the Mouse Liver

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Results for Nkx3-2

Z-value: 0.92

Motif logo

Transcription factors associated with Nkx3-2

Gene Symbol Gene ID Gene Info
ENSMUSG00000049691.7 NK3 homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nkx3-2mm10_v2_chr5_-_41764493_417644960.501.8e-03Click!

Activity profile of Nkx3-2 motif

Sorted Z-values of Nkx3-2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr14_-_20269162 8.70 ENSMUST00000024155.7
potassium channel, subfamily K, member 16
chr5_+_90490714 6.79 ENSMUST00000042755.3
alpha fetoprotein
chr7_-_103853199 5.38 ENSMUST00000033229.3
hemoglobin Y, beta-like embryonic chain
chr8_+_80494032 5.26 ENSMUST00000063359.6
glycophorin A
chr1_+_91366412 4.81 ENSMUST00000086861.5
family with sequence similarity 132, member B
chrX_-_136203637 4.64 ENSMUST00000151592.1
ENSMUST00000131510.1
ENSMUST00000066819.4
transcription elongation factor A (SII)-like 5
chr7_+_143005770 4.63 ENSMUST00000143512.1
tetraspanin 32
chr7_+_143005677 4.58 ENSMUST00000082008.5
ENSMUST00000105925.1
ENSMUST00000105924.1
tetraspanin 32
chr14_+_80000292 4.55 ENSMUST00000088735.3
olfactomedin 4
chr1_-_75133866 4.49 ENSMUST00000027405.4
solute carrier family 23 (nucleobase transporters), member 3
chr7_+_143005638 4.45 ENSMUST00000075172.5
ENSMUST00000105923.1
tetraspanin 32
chrX_-_102252154 4.26 ENSMUST00000050551.3
Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1
chr10_+_79879614 4.21 ENSMUST00000006679.8
proteinase 3
chr8_+_75213944 3.88 ENSMUST00000139848.1
RASD family, member 2
chr19_-_24555819 3.65 ENSMUST00000112673.2
ENSMUST00000025800.8
phosphatidylinositol-4-phosphate 5-kinase, type 1 beta
chr11_+_120948480 3.50 ENSMUST00000070653.6
solute carrier family 16 (monocarboxylic acid transporters), member 3
chr4_-_4138432 3.48 ENSMUST00000070375.7
preproenkephalin
chr11_+_120949053 3.44 ENSMUST00000154187.1
ENSMUST00000100130.3
ENSMUST00000129473.1
ENSMUST00000168579.1
solute carrier family 16 (monocarboxylic acid transporters), member 3
chr17_-_43543639 3.12 ENSMUST00000178772.1
ankyrin repeat domain 66
chr15_-_103252810 3.07 ENSMUST00000154510.1
nuclear factor, erythroid derived 2
chrX_-_93832106 2.84 ENSMUST00000045748.6
pyruvate dehydrogenase kinase, isoenzyme 3
chr8_+_75214502 2.72 ENSMUST00000132133.1
RASD family, member 2
chr4_-_4138817 2.64 ENSMUST00000133567.1
preproenkephalin
chr8_-_85380964 2.56 ENSMUST00000122452.1
myosin light chain kinase 3
chr1_-_193035651 2.46 ENSMUST00000016344.7
synaptotagmin XIV
chr11_+_82892116 2.31 ENSMUST00000018988.5
fibronectin type III domain containing 8
chr9_+_112234257 2.23 ENSMUST00000149308.3
ENSMUST00000144424.2
ENSMUST00000139552.2
RIKEN cDNA 2900079G21 gene
chr7_+_97453204 2.19 ENSMUST00000050732.7
ENSMUST00000121987.1
potassium channel tetramerisation domain containing 14
chr7_+_43427622 1.98 ENSMUST00000177164.2
lens intrinsic membrane protein 2
chr7_+_43351378 1.93 ENSMUST00000012798.7
ENSMUST00000122423.1
ENSMUST00000121494.1
sialic acid binding Ig-like lectin 5
chr8_-_85386310 1.76 ENSMUST00000137290.1
myosin light chain kinase 3
chr8_-_122551316 1.72 ENSMUST00000067252.7
piezo-type mechanosensitive ion channel component 1
chr14_+_55650170 1.68 ENSMUST00000164809.1
ENSMUST00000007735.8
testis-specific serine kinase 4
chr18_+_27598582 1.61 ENSMUST00000050143.3
predicted gene 7729
chr2_+_32363004 1.59 ENSMUST00000132028.1
ENSMUST00000136079.1
CDKN1A interacting zinc finger protein 1
chr11_+_117782358 1.57 ENSMUST00000117781.1
transmembrane channel-like gene family 8
chr9_+_57940104 1.57 ENSMUST00000043059.7
sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A
chr10_+_80016653 1.57 ENSMUST00000099501.3
histocompatibility (minor) HA-1
chr19_-_4877882 1.57 ENSMUST00000006626.3
actinin alpha 3
chr8_+_45885479 1.56 ENSMUST00000034053.5
PDZ and LIM domain 3
chr11_+_117782076 1.52 ENSMUST00000127080.1
transmembrane channel-like gene family 8
chr4_-_117929726 1.51 ENSMUST00000070816.2
artemin
chr11_+_117782281 1.49 ENSMUST00000050874.7
ENSMUST00000106334.2
transmembrane channel-like gene family 8
chr18_-_62179948 1.48 ENSMUST00000053640.3
adrenergic receptor, beta 2
chr15_-_56694525 1.48 ENSMUST00000050544.7
hyaluronan synthase 2
chr6_+_49367739 1.47 ENSMUST00000060561.8
ENSMUST00000121903.1
ENSMUST00000134786.1
family with sequence similarity 221, member A
chr11_+_35121126 1.45 ENSMUST00000069837.3
slit homolog 3 (Drosophila)
chr8_-_4779513 1.44 ENSMUST00000022945.7
Shc SH2-domain binding protein 1
chr19_-_34255325 1.43 ENSMUST00000039631.8
actin, alpha 2, smooth muscle, aorta
chr5_+_115466234 1.43 ENSMUST00000145785.1
ENSMUST00000031495.4
ENSMUST00000112071.1
ENSMUST00000125568.1
phospholipase A2, group IB, pancreas
chr11_-_69560186 1.43 ENSMUST00000004036.5
ephrin B3
chrX_+_37048807 1.43 ENSMUST00000060057.1
sosondowah ankyrin repeat domain family member D
chr13_-_19619820 1.40 ENSMUST00000002885.6
ependymin related protein 1 (zebrafish)
chr13_+_44729535 1.40 ENSMUST00000174068.1
jumonji, AT rich interactive domain 2
chr10_-_86732409 1.37 ENSMUST00000070435.4
fatty acid binding protein 3, muscle and heart, pseudogene 1
chr7_-_110982443 1.37 ENSMUST00000005751.6
MRV integration site 1
chr4_-_131838231 1.36 ENSMUST00000030741.2
ENSMUST00000105987.2
protein tyrosine phosphatase, receptor type, U
chr3_+_95164306 1.34 ENSMUST00000107217.1
ENSMUST00000168321.1
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C
chr2_-_32353283 1.34 ENSMUST00000091089.5
ENSMUST00000113350.1
dynamin 1
chr7_+_30280094 1.34 ENSMUST00000108187.1
ENSMUST00000014072.5
THAP domain containing 8
chr5_+_72647779 1.32 ENSMUST00000087212.3
NIPA-like domain containing 1
chr7_+_127904079 1.31 ENSMUST00000071056.7
branched chain ketoacid dehydrogenase kinase
chr11_+_3332426 1.31 ENSMUST00000136474.1
phosphoinositide-3-kinase interacting protein 1
chr3_-_67463828 1.30 ENSMUST00000058981.2
latexin
chr15_-_100669535 1.30 ENSMUST00000183211.1
bridging integrator 2
chr8_+_83666827 1.30 ENSMUST00000019608.5
prostaglandin E receptor 1 (subtype EP1)
chr4_+_63558748 1.29 ENSMUST00000077709.4
RIKEN cDNA 6330416G13 gene
chr11_-_117782182 1.27 ENSMUST00000152304.1
transmembrane channel-like gene family 6
chr6_-_125494754 1.27 ENSMUST00000032492.8
CD9 antigen
chr1_-_181842334 1.22 ENSMUST00000005003.6
lamin B receptor
chr16_+_33062512 1.20 ENSMUST00000023497.2
leishmanolysin-like (metallopeptidase M8 family)
chr16_+_21204755 1.17 ENSMUST00000006112.6
Eph receptor B3
chr4_+_130360132 1.15 ENSMUST00000105994.3
small nuclear ribonucleoprotein 40 (U5)
chr10_+_42860348 1.14 ENSMUST00000063063.7
sex comb on midleg-like 4 (Drosophila)
chr1_+_180904274 1.13 ENSMUST00000027802.7
pyrroline-5-carboxylate reductase family, member 2
chr2_+_32363163 1.09 ENSMUST00000145635.1
CDKN1A interacting zinc finger protein 1
chr2_+_26330391 1.09 ENSMUST00000114134.2
ENSMUST00000127453.1
G-protein signalling modulator 1 (AGS3-like, C. elegans)
chr19_+_8740712 1.08 ENSMUST00000163172.1
RIKEN cDNA 1700092M07 gene
chr2_-_164404606 1.06 ENSMUST00000109359.1
ENSMUST00000109358.1
ENSMUST00000103103.3
matrilin 4
chr4_-_133872304 1.06 ENSMUST00000157067.2
ribosomal protein S6 kinase polypeptide 1
chr17_+_78882003 1.04 ENSMUST00000180880.1
predicted gene, 26637
chr6_-_29216301 1.01 ENSMUST00000162739.1
ENSMUST00000162099.1
ENSMUST00000159124.1
inosine 5'-phosphate dehydrogenase 1
chr7_+_92741603 1.00 ENSMUST00000032879.7
RAB30, member RAS oncogene family
chr11_+_70017085 1.00 ENSMUST00000108589.2
discs, large homolog 4 (Drosophila)
chr13_+_44729794 0.99 ENSMUST00000172830.1
jumonji, AT rich interactive domain 2
chr16_-_19200350 0.98 ENSMUST00000103749.2
immunoglobulin lambda constant 2
chrX_+_101274023 0.95 ENSMUST00000117706.1
mediator of RNA polymerase II transcription, subunit 12 homolog (yeast)
chr17_+_46161111 0.94 ENSMUST00000166563.1
GTP binding protein 2
chr15_-_66969616 0.94 ENSMUST00000170903.1
ENSMUST00000166420.1
ENSMUST00000005256.6
ENSMUST00000164070.1
N-myc downstream regulated gene 1
chr2_-_166581969 0.93 ENSMUST00000109246.1
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
chrX_+_153139941 0.93 ENSMUST00000039720.4
ENSMUST00000144175.2
Ras-related GTP binding B
chr1_+_135836380 0.92 ENSMUST00000178204.1
troponin T2, cardiac
chr2_+_24386604 0.92 ENSMUST00000166388.1
pleckstrin and Sec7 domain containing 4
chr9_+_72806874 0.91 ENSMUST00000055535.8
protogenin homolog (Gallus gallus)
chr9_-_61976563 0.89 ENSMUST00000113990.1
progestin and adipoQ receptor family member V
chr2_-_118549668 0.87 ENSMUST00000090219.6
BCL2 modifying factor
chr9_+_43310763 0.86 ENSMUST00000034511.5
tripartite motif-containing 29
chr2_-_35461365 0.85 ENSMUST00000102794.1
glycoprotein galactosyltransferase alpha 1, 3
chr13_-_30974023 0.85 ENSMUST00000021785.6
exocyst complex component 2
chr2_-_35461247 0.81 ENSMUST00000113001.2
ENSMUST00000113002.2
glycoprotein galactosyltransferase alpha 1, 3
chr11_+_70000578 0.81 ENSMUST00000019362.8
dishevelled 2, dsh homolog (Drosophila)
chr10_+_79996479 0.81 ENSMUST00000132517.1
ATP-binding cassette, sub-family A (ABC1), member 7
chr5_-_139130159 0.81 ENSMUST00000129851.1
protein kinase, cAMP dependent regulatory, type I beta
chr1_+_172482199 0.80 ENSMUST00000135267.1
ENSMUST00000052629.6
ENSMUST00000111235.2
immunoglobulin superfamily, member 9
chr2_+_32363192 0.78 ENSMUST00000048964.7
ENSMUST00000113332.1
CDKN1A interacting zinc finger protein 1
chr4_+_130047840 0.77 ENSMUST00000044565.8
ENSMUST00000132251.1
collagen, type XVI, alpha 1
chr4_-_58206596 0.77 ENSMUST00000042850.8
sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
chr15_+_11064764 0.76 ENSMUST00000061318.7
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 12
chr2_+_28447941 0.75 ENSMUST00000040324.7
protein phosphatase 1, regulatory subunit 26
chr3_-_97227364 0.74 ENSMUST00000046521.7
B cell CLL/lymphoma 9
chr5_-_134314637 0.73 ENSMUST00000173504.1
general transcription factor II I
chr19_-_53371766 0.71 ENSMUST00000086887.1
predicted gene 10197
chr4_-_151044564 0.70 ENSMUST00000103204.4
period circadian clock 3
chr11_+_101987050 0.70 ENSMUST00000010985.7
RIKEN cDNA 1700006E09 gene
chr2_-_54085542 0.70 ENSMUST00000100089.2
reprimo, TP53 dependent G2 arrest mediator candidate
chr13_+_30136529 0.69 ENSMUST00000152798.1
membrane bound O-acyltransferase domain containing 1
chr19_+_45047557 0.69 ENSMUST00000062213.5
ENSMUST00000111954.4
ENSMUST00000084493.6
sideroflexin 3
chr4_+_149586432 0.66 ENSMUST00000105691.1
calsyntenin 1
chr19_+_41593363 0.66 ENSMUST00000099454.3
expressed sequence AI606181
chr10_-_128919259 0.65 ENSMUST00000149961.1
ENSMUST00000026406.7
retinol dehydrogenase 5
chr9_-_45269135 0.65 ENSMUST00000176222.1
ENSMUST00000034594.9
interleukin 10 receptor, alpha
chr2_-_34755229 0.65 ENSMUST00000102800.1
GTPase activating protein and VPS9 domains 1
chr8_+_106510853 0.64 ENSMUST00000080797.6
cadherin 3
chr4_+_130047914 0.64 ENSMUST00000142293.1
collagen, type XVI, alpha 1
chr15_-_75888754 0.63 ENSMUST00000184858.1
maestro heat-like repeat family member 6
chr16_+_44347121 0.63 ENSMUST00000050897.6
spindle and centriole associated protein 1
chrX_+_166170449 0.61 ENSMUST00000130880.2
ENSMUST00000056410.4
ENSMUST00000096252.3
ENSMUST00000087169.4
gem (nuclear organelle) associated protein 8
chr2_-_113848655 0.61 ENSMUST00000102545.1
ENSMUST00000110948.1
Rho GTPase activating protein 11A
chr3_+_109573907 0.60 ENSMUST00000106576.2
vav 3 oncogene
chr8_-_107263248 0.60 ENSMUST00000080443.6
ribosomal protein S18, pseudogene 3
chr7_+_25221417 0.60 ENSMUST00000055604.4
zinc finger protein 526
chr3_-_89245829 0.59 ENSMUST00000041022.8
tripartite motif-containing 46
chr18_+_73863672 0.58 ENSMUST00000134847.1
maestro
chr17_+_34593388 0.57 ENSMUST00000174532.1
pre B cell leukemia homeobox 2
chr16_+_22892035 0.57 ENSMUST00000023583.5
alpha-2-HS-glycoprotein
chr9_-_21037775 0.56 ENSMUST00000180870.1
predicted gene, 26592
chr11_+_70017199 0.56 ENSMUST00000133140.1
discs, large homolog 4 (Drosophila)
chr8_+_104340594 0.56 ENSMUST00000034343.4
CKLF-like MARVEL transmembrane domain containing 3
chr2_+_120629113 0.55 ENSMUST00000150912.1
ENSMUST00000180041.1
START domain containing 9
chr8_-_122678072 0.55 ENSMUST00000006525.7
ENSMUST00000064674.6
core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)
chrX_-_101269023 0.54 ENSMUST00000117736.1
predicted gene 20489
chr8_-_104631312 0.54 ENSMUST00000034351.6
Ras-related associated with diabetes
chr11_+_59542686 0.54 ENSMUST00000101148.2
NLR family, pyrin domain containing 3
chr4_-_106492283 0.54 ENSMUST00000054472.3
Bartter syndrome, infantile, with sensorineural deafness (Barttin)
chr4_-_56802265 0.53 ENSMUST00000030140.2
inhibitor of kappa light polypeptide enhancer in B cells, kinase complex-associated protein
chr7_-_19359477 0.53 ENSMUST00000047036.8
CD3E antigen, epsilon polypeptide associated protein
chr7_-_42793496 0.52 ENSMUST00000169130.1
vomeronasal 2, receptor 62
chr2_+_158794807 0.52 ENSMUST00000029186.7
ENSMUST00000109478.2
ENSMUST00000156893.1
DEAH (Asp-Glu-Ala-His) box polypeptide 35
chr4_-_129121699 0.51 ENSMUST00000135763.1
ENSMUST00000149763.1
ENSMUST00000164649.1
hippocalcin
chr10_+_53596936 0.50 ENSMUST00000020004.6
ASF1 anti-silencing function 1 homolog A (S. cerevisiae)
chr1_-_65032738 0.50 ENSMUST00000162800.1
ENSMUST00000069142.5
aldo-keto reductase family 1, member C-like
chr9_-_43116514 0.50 ENSMUST00000061833.4
transmembrane protein 136
chr7_-_125491586 0.50 ENSMUST00000033006.7
non-SMC element 1 homolog (S. cerevisiae)
chr3_-_108415552 0.49 ENSMUST00000090558.3
cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)
chr2_-_156992021 0.47 ENSMUST00000109558.1
ENSMUST00000069600.6
ENSMUST00000072298.6
N-myc downstream regulated gene 3
chr4_-_141598206 0.46 ENSMUST00000131317.1
ENSMUST00000006381.4
ENSMUST00000129602.1
filamin binding LIM protein 1
chr5_+_114003833 0.46 ENSMUST00000086599.4
D-amino acid oxidase
chr10_-_30842765 0.45 ENSMUST00000019924.8
hairy/enhancer-of-split related with YRPW motif 2
chr3_+_129199878 0.45 ENSMUST00000174661.2
paired-like homeodomain transcription factor 2
chr13_+_23782572 0.45 ENSMUST00000074067.2
tripartite motif-containing 38
chr11_+_73234292 0.44 ENSMUST00000102526.2
transient receptor potential cation channel, subfamily V, member 1
chrX_+_142681398 0.43 ENSMUST00000112889.1
ENSMUST00000101198.2
ENSMUST00000112891.1
ENSMUST00000087333.2
transmembrane protein 164
chr2_+_122315672 0.43 ENSMUST00000099461.3
dual oxidase 1
chr4_+_56802337 0.43 ENSMUST00000045368.5
cDNA sequence BC026590
chr11_+_72689997 0.43 ENSMUST00000155998.1
ankyrin repeat and FYVE domain containing 1
chr1_+_161070767 0.43 ENSMUST00000111618.1
ENSMUST00000111620.3
ENSMUST00000028035.7
centromere protein L
chrX_-_7947553 0.42 ENSMUST00000133349.1
histone deacetylase 6
chr6_-_56362356 0.41 ENSMUST00000044505.7
ENSMUST00000166102.1
ENSMUST00000164037.1
ENSMUST00000114327.2
phosphodiesterase 1C
chr15_+_11000716 0.41 ENSMUST00000117100.1
ENSMUST00000022851.7
solute carrier family 45, member 2
chrX_+_140956892 0.39 ENSMUST00000112971.1
autophagy related 4A, cysteine peptidase
chr6_+_78370877 0.39 ENSMUST00000096904.3
regenerating islet-derived 3 beta
chr1_-_13127163 0.39 ENSMUST00000047577.6
PR domain containing 14
chr13_-_24761440 0.39 ENSMUST00000176890.1
ENSMUST00000175689.1
geminin
chr8_-_112011266 0.39 ENSMUST00000164470.1
ENSMUST00000093120.5
lysyl-tRNA synthetase
chr2_+_121506748 0.39 ENSMUST00000099473.3
ENSMUST00000110602.2
WD repeat domain 76
chr7_-_30861470 0.39 ENSMUST00000052700.3
free fatty acid receptor 1
chr16_-_31081363 0.39 ENSMUST00000055389.7
xyloside xylosyltransferase 1
chr6_+_83135812 0.38 ENSMUST00000065512.4
rhotekin
chr19_-_4121536 0.38 ENSMUST00000025767.7
aryl-hydrocarbon receptor-interacting protein
chr8_-_94098811 0.37 ENSMUST00000034206.4
Bardet-Biedl syndrome 2 (human)
chr6_-_72380416 0.37 ENSMUST00000101285.3
ENSMUST00000074231.3
vesicle-associated membrane protein 5
chr4_+_129491190 0.37 ENSMUST00000106043.2
family with sequence similarity 229, member A
chr4_-_132884509 0.37 ENSMUST00000030698.4
syntaxin 12
chr7_+_31059342 0.37 ENSMUST00000039775.7
leucine-rich repeat LGI family, member 4
chr5_-_110839575 0.36 ENSMUST00000145318.1
HscB iron-sulfur cluster co-chaperone homolog (E. coli)
chr8_-_84067283 0.36 ENSMUST00000071067.3
RIKEN cDNA C330011M18 gene
chr8_-_112011320 0.36 ENSMUST00000034426.6
lysyl-tRNA synthetase
chrX_-_7947848 0.35 ENSMUST00000115642.1
ENSMUST00000033501.8
ENSMUST00000145675.1
histone deacetylase 6
chr1_+_164048214 0.34 ENSMUST00000027874.5
selectin, endothelial cell
chr7_-_25882407 0.33 ENSMUST00000163316.2
predicted gene 6434
chr11_+_69995777 0.33 ENSMUST00000018716.3
PHD finger protein 23
chr16_+_20535475 0.33 ENSMUST00000090023.6
ENSMUST00000007216.8
adaptor-related protein complex 2, mu 1 subunit
chr19_+_4839366 0.33 ENSMUST00000088653.2
coiled-coil domain containing 87
chr11_-_120731944 0.32 ENSMUST00000154565.1
ENSMUST00000026148.2
carbonyl reductase 2
chr14_+_53763083 0.32 ENSMUST00000180859.1
ENSMUST00000103589.4
T cell receptor alpha variable 14-3
chr7_-_128237984 0.32 ENSMUST00000078816.3
RIKEN cDNA 9130023H24 gene
chr11_-_69795930 0.32 ENSMUST00000045971.8
cholinergic receptor, nicotinic, beta polypeptide 1 (muscle)
chr1_+_17727034 0.30 ENSMUST00000159958.1
ENSMUST00000160305.1
ENSMUST00000095075.4
cysteine-rich secretory protein LCCL domain containing 1
chr5_+_149411749 0.30 ENSMUST00000093110.5
mesenteric estrogen dependent adipogenesis
chrX_-_7947763 0.30 ENSMUST00000154244.1
histone deacetylase 6

Network of associatons between targets according to the STRING database.

First level regulatory network of Nkx3-2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 13.7 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
1.0 6.1 GO:2000987 positive regulation of fear response(GO:1903367) positive regulation of behavioral fear response(GO:2000987)
0.9 4.3 GO:0071105 response to interleukin-9(GO:0071104) response to interleukin-11(GO:0071105)
0.8 4.2 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.8 1.5 GO:0097021 lymphocyte migration into lymphoid organs(GO:0097021)
0.7 3.6 GO:0032298 positive regulation of DNA-dependent DNA replication initiation(GO:0032298)
0.7 4.3 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.7 2.8 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.7 6.9 GO:0015727 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.7 5.4 GO:0015671 oxygen transport(GO:0015671)
0.7 5.3 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.6 8.7 GO:0030322 stabilization of membrane potential(GO:0030322)
0.5 1.6 GO:1902688 regulation of fermentation(GO:0043465) regulation of bone mineralization involved in bone maturation(GO:1900157) regulation of NAD metabolic process(GO:1902688) regulation of glucose catabolic process to lactate via pyruvate(GO:1904023)
0.5 1.5 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.5 1.4 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.4 1.7 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.4 6.8 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.4 1.7 GO:0042125 protein glycosylation at cell surface(GO:0033575) protein galactosylation at cell surface(GO:0033580) protein galactosylation(GO:0042125)
0.4 1.5 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.4 1.1 GO:0070845 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.3 2.5 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.3 0.9 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.3 0.8 GO:1901074 regulation of engulfment of apoptotic cell(GO:1901074)
0.3 3.1 GO:0034242 negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.2 0.7 GO:0002276 basophil activation involved in immune response(GO:0002276)
0.2 6.6 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.2 1.4 GO:0070100 negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.2 1.7 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.2 0.9 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.2 0.5 GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
0.2 1.5 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.2 1.3 GO:0030913 paranodal junction assembly(GO:0030913)
0.2 1.0 GO:0006177 GMP biosynthetic process(GO:0006177)
0.2 0.8 GO:0030167 proteoglycan catabolic process(GO:0030167) regulation of endothelial tube morphogenesis(GO:1901509) regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202) negative regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902548)
0.2 1.4 GO:0016198 axon choice point recognition(GO:0016198)
0.2 4.6 GO:0032460 negative regulation of protein oligomerization(GO:0032460)
0.2 0.5 GO:0031283 negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283)
0.2 2.4 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.2 0.8 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.2 1.1 GO:0006561 proline biosynthetic process(GO:0006561)
0.2 0.6 GO:0051794 regulation of catagen(GO:0051794)
0.2 0.5 GO:0046144 D-serine catabolic process(GO:0036088) D-alanine family amino acid metabolic process(GO:0046144) D-alanine metabolic process(GO:0046436) D-alanine catabolic process(GO:0055130)
0.1 0.7 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.1 0.4 GO:0042335 cuticle development(GO:0042335)
0.1 1.6 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.1 0.8 GO:0001927 exocyst assembly(GO:0001927)
0.1 0.9 GO:0090245 embryonic neurocranium morphogenesis(GO:0048702) axis elongation involved in somitogenesis(GO:0090245)
0.1 0.5 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 1.6 GO:0099628 receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
0.1 0.4 GO:1901594 detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594)
0.1 0.4 GO:0015770 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.1 0.5 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.1 0.4 GO:1902093 inner cell mass cell fate commitment(GO:0001827) positive regulation of sperm motility(GO:1902093)
0.1 1.4 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.1 0.9 GO:0048102 autophagic cell death(GO:0048102)
0.1 0.4 GO:0051344 negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.1 0.4 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.1 0.9 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.1 0.5 GO:0060578 subthalamic nucleus development(GO:0021763) superior vena cava morphogenesis(GO:0060578)
0.1 0.5 GO:0050713 negative regulation of interleukin-1 beta secretion(GO:0050713)
0.1 5.3 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1 1.7 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.1 0.9 GO:0090232 positive regulation of spindle checkpoint(GO:0090232)
0.1 0.4 GO:0051697 protein delipidation(GO:0051697)
0.1 1.3 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.1 0.3 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.1 1.9 GO:0033622 integrin activation(GO:0033622)
0.1 0.4 GO:0048549 endosome localization(GO:0032439) positive regulation of pinocytosis(GO:0048549)
0.1 0.6 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1 0.3 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.1 1.3 GO:0015693 magnesium ion transport(GO:0015693)
0.1 0.5 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.1 0.5 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.1 3.7 GO:0006661 phosphatidylinositol biosynthetic process(GO:0006661)
0.1 0.4 GO:0016266 O-glycan processing(GO:0016266)
0.1 1.1 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.1 0.3 GO:0006116 NADH oxidation(GO:0006116)
0.1 0.4 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.4 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 0.5 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.2 GO:1903011 negative regulation of bone development(GO:1903011) negative regulation of osteoclast development(GO:2001205)
0.0 1.3 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.4 GO:1903208 neuron death in response to hydrogen peroxide(GO:0036476) regulation of hydrogen peroxide-induced neuron death(GO:1903207) negative regulation of hydrogen peroxide-induced neuron death(GO:1903208)
0.0 0.2 GO:2001045 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.2 GO:2001046 positive regulation of integrin-mediated signaling pathway(GO:2001046)
0.0 0.5 GO:0050961 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0 0.6 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 0.1 GO:0016479 negative regulation of transcription from RNA polymerase I promoter(GO:0016479)
0.0 0.6 GO:0099612 protein localization to axon(GO:0099612)
0.0 0.3 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 1.2 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.3 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.0 0.9 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.2 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.6 GO:0046599 regulation of centriole replication(GO:0046599)
0.0 0.6 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0 0.3 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.7 GO:0045187 regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.0 0.3 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.1 GO:0009838 abscission(GO:0009838)
0.0 0.4 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 2.0 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.7 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.0 0.2 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.5 GO:0006301 postreplication repair(GO:0006301)
0.0 0.5 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.1 GO:0061198 fungiform papilla formation(GO:0061198)
0.0 0.7 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.4 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.3 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 0.5 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 1.1 GO:0048678 response to axon injury(GO:0048678)
0.0 0.3 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.0 0.4 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.5 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 1.7 GO:0050807 regulation of synapse organization(GO:0050807)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 13.7 GO:0070442 integrin alphaIIb-beta3 complex(GO:0070442)
1.5 6.1 GO:0032280 symmetric synapse(GO:0032280)
0.7 5.4 GO:0005833 hemoglobin complex(GO:0005833)
0.3 1.3 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.3 4.6 GO:0042581 specific granule(GO:0042581)
0.3 3.7 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.2 1.4 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.2 0.9 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.2 0.9 GO:1990584 cardiac Troponin complex(GO:1990584)
0.1 0.6 GO:1990769 proximal neuron projection(GO:1990769)
0.1 0.3 GO:0071920 cleavage body(GO:0071920)
0.1 2.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 1.8 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 0.5 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.1 0.4 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 0.5 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 2.2 GO:0001891 phagocytic cup(GO:0001891)
0.1 0.5 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.1 1.2 GO:0005652 nuclear lamina(GO:0005652)
0.1 0.2 GO:0036125 mitochondrial fatty acid beta-oxidation multienzyme complex(GO:0016507) fatty acid beta-oxidation multienzyme complex(GO:0036125)
0.1 0.4 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 1.3 GO:0043196 varicosity(GO:0043196)
0.1 1.0 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 0.5 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.6 GO:0032797 SMN complex(GO:0032797)
0.0 0.7 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.4 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.0 0.3 GO:0001652 granular component(GO:0001652)
0.0 1.5 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 0.8 GO:0000145 exocyst(GO:0000145)
0.0 2.7 GO:0031985 Golgi cisterna(GO:0031985)
0.0 1.1 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 0.5 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 1.9 GO:0016235 aggresome(GO:0016235)
0.0 1.2 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.5 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.3 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.8 GO:0060077 inhibitory synapse(GO:0060077)
0.0 6.8 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.9 GO:0016592 mediator complex(GO:0016592)
0.0 0.9 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 2.3 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.1 GO:0090543 Flemming body(GO:0090543)
0.0 0.4 GO:0042588 zymogen granule(GO:0042588)
0.0 5.4 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 1.5 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.1 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 2.4 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.5 GO:0005801 cis-Golgi network(GO:0005801)
0.0 1.1 GO:0005581 collagen trimer(GO:0005581)
0.0 1.7 GO:0005923 bicellular tight junction(GO:0005923)
0.0 1.2 GO:0005814 centriole(GO:0005814)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 6.8 GO:0004566 beta-glucuronidase activity(GO:0004566)
1.3 5.4 GO:0031721 hemoglobin alpha binding(GO:0031721)
1.0 6.9 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.9 6.1 GO:0001515 opioid peptide activity(GO:0001515)
0.7 2.8 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.6 4.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.5 8.7 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.5 1.5 GO:0030116 glial cell-derived neurotrophic factor receptor binding(GO:0030116)
0.5 3.9 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.4 1.5 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.4 1.5 GO:0004939 beta-adrenergic receptor activity(GO:0004939) bradykinin receptor binding(GO:0031711)
0.4 1.5 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.3 6.6 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.3 4.3 GO:0050693 LBD domain binding(GO:0050693)
0.3 1.1 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.3 1.7 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.3 0.8 GO:0090556 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.3 1.1 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.3 1.0 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.2 1.6 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.2 1.3 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.2 1.4 GO:0048495 Roundabout binding(GO:0048495)
0.2 7.7 GO:0050699 WW domain binding(GO:0050699)
0.2 1.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.2 1.4 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.2 1.2 GO:0070087 chromo shadow domain binding(GO:0070087)
0.2 0.5 GO:0035939 microsatellite binding(GO:0035939)
0.1 0.9 GO:0031013 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.1 0.4 GO:0036004 GAF domain binding(GO:0036004)
0.1 0.5 GO:0003884 D-amino-acid oxidase activity(GO:0003884)
0.1 0.6 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.1 0.4 GO:0015157 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.1 1.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.7 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.1 1.6 GO:0038191 neuropilin binding(GO:0038191)
0.1 2.0 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.4 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.1 1.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.8 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 0.3 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.1 0.4 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 3.6 GO:0030332 cyclin binding(GO:0030332)
0.1 0.5 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.1 0.7 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.1 0.4 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.1 1.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 0.4 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 1.7 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.2 GO:0016509 long-chain-enoyl-CoA hydratase activity(GO:0016508) long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 1.1 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 2.9 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 2.1 GO:0032452 histone demethylase activity(GO:0032452)
0.0 1.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.2 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 1.0 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.8 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.3 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.2 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 0.2 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.7 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.7 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.5 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.9 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 1.6 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.1 GO:0035851 Krueppel-associated box domain binding(GO:0035851)
0.0 1.4 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.2 GO:0035662 Toll-like receptor 4 binding(GO:0035662) vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 1.2 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.7 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.2 GO:0034511 U3 snoRNA binding(GO:0034511)
0.0 2.7 GO:0005178 integrin binding(GO:0005178)
0.0 1.1 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.4 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.0 0.5 GO:0031005 filamin binding(GO:0031005)
0.0 0.3 GO:0042166 acetylcholine binding(GO:0042166)
0.0 3.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 1.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.7 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.8 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.8 GO:0005109 frizzled binding(GO:0005109)
0.0 0.2 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.8 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.7 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 1.5 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.3 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.3 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 1.6 GO:0030674 protein binding, bridging(GO:0030674)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.5 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 1.4 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.1 5.4 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 1.8 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 3.8 PID EPHB FWD PATHWAY EPHB forward signaling
0.1 2.0 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 4.0 PID AP1 PATHWAY AP-1 transcription factor network
0.0 4.3 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 3.5 PID CMYB PATHWAY C-MYB transcription factor network
0.0 1.2 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 1.5 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.9 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 1.4 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 1.6 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 5.9 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.4 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.7 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.4 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 1.4 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.8 PID INSULIN PATHWAY Insulin Pathway
0.0 1.3 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.3 PID ARF 3PATHWAY Arf1 pathway
0.0 0.9 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.5 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 2.4 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.1 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.5 PID HES HEY PATHWAY Notch-mediated HES/HEY network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 8.7 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.5 6.9 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.2 2.1 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 1.3 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.1 2.1 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 1.7 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 1.5 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.1 1.0 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 3.7 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 1.6 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.5 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.8 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 1.5 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 1.4 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.8 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.8 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 5.5 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.9 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.4 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 1.1 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.4 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 1.5 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.7 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 1.1 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 1.3 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 1.6 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 1.7 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 0.6 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.3 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.3 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.1 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.1 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.9 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation