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GSE58827: Dynamics of the Mouse Liver

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Results for Nkx6-3_Dbx2_Barx2

Z-value: 0.70

Motif logo

Transcription factors associated with Nkx6-3_Dbx2_Barx2

Gene Symbol Gene ID Gene Info
ENSMUSG00000063672.6 NK6 homeobox 3
ENSMUSG00000045608.6 developing brain homeobox 2
ENSMUSG00000032033.10 BarH-like homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Dbx2mm10_v2_chr15_-_95655960_956559600.212.2e-01Click!
Barx2mm10_v2_chr9_-_31913462_319134830.105.7e-01Click!
Nkx6-3mm10_v2_chr8_+_23153271_231532710.067.2e-01Click!

Activity profile of Nkx6-3_Dbx2_Barx2 motif

Sorted Z-values of Nkx6-3_Dbx2_Barx2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr14_+_27000362 6.77 ENSMUST00000035433.8
homeobox gene expressed in ES cells
chr14_+_80000292 4.30 ENSMUST00000088735.3
olfactomedin 4
chr1_+_174172738 3.65 ENSMUST00000027817.7
spectrin alpha, erythrocytic 1
chr1_+_139454747 2.69 ENSMUST00000053364.8
ENSMUST00000097554.3
asp (abnormal spindle)-like, microcephaly associated (Drosophila)
chr2_-_160619971 2.47 ENSMUST00000109473.1
predicted gene 14221
chr7_+_43427622 2.44 ENSMUST00000177164.2
lens intrinsic membrane protein 2
chr17_-_48432723 2.42 ENSMUST00000046549.3
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2
chr2_-_168767136 2.40 ENSMUST00000029061.5
ENSMUST00000103074.1
sal-like 4 (Drosophila)
chr4_+_34893772 2.07 ENSMUST00000029975.3
ENSMUST00000135871.1
ENSMUST00000108130.1
glycoprotein hormones, alpha subunit
chr10_+_37139558 1.95 ENSMUST00000062667.3
RIKEN cDNA 5930403N24 gene
chr7_+_45621805 1.94 ENSMUST00000033100.4
izumo sperm-egg fusion 1
chr10_-_76110956 1.90 ENSMUST00000120757.1
solute carrier family 5 (neutral amino acid transporters, system A), member 4b
chr2_-_168767029 1.89 ENSMUST00000075044.3
sal-like 4 (Drosophila)
chr5_-_118244861 1.61 ENSMUST00000117177.1
ENSMUST00000133372.1
ENSMUST00000154786.1
ENSMUST00000121369.1
ring finger protein, transmembrane 2
chr1_-_172027269 1.59 ENSMUST00000027837.6
ENSMUST00000111264.1
vang-like 2 (van gogh, Drosophila)
chr11_-_11970540 1.57 ENSMUST00000109653.1
growth factor receptor bound protein 10
chr1_+_40439767 1.53 ENSMUST00000173514.1
interleukin 1 receptor-like 1
chr1_+_40439627 1.50 ENSMUST00000097772.3
interleukin 1 receptor-like 1
chr2_-_121235689 1.46 ENSMUST00000142400.1
transformation related protein 53 binding protein 1
chr11_-_17008647 1.38 ENSMUST00000102881.3
pleckstrin
chr2_+_36230426 1.35 ENSMUST00000062069.5
prostaglandin-endoperoxide synthase 1
chr8_-_62123106 1.35 ENSMUST00000034052.6
ENSMUST00000034054.7
annexin A10
chr9_+_72806874 1.34 ENSMUST00000055535.8
protogenin homolog (Gallus gallus)
chr16_-_76022266 1.32 ENSMUST00000114240.1
SAM domain, SH3 domain and nuclear localization signals, 1
chr10_-_37138863 1.30 ENSMUST00000092584.5
myristoylated alanine rich protein kinase C substrate
chr6_+_38109320 1.29 ENSMUST00000031851.3
transmembrane protein 213
chr13_-_58354862 1.25 ENSMUST00000043605.5
kinesin family member 27
chr8_+_94172618 1.25 ENSMUST00000034214.6
metallothionein 2
chr7_-_133702515 1.23 ENSMUST00000153698.1
uroporphyrinogen III synthase
chr2_-_32387760 1.20 ENSMUST00000050785.8
lipocalin 2
chr14_+_58893465 1.15 ENSMUST00000079960.1
ribosomal protein L13, pseudogene 3
chr11_-_99244058 1.14 ENSMUST00000103132.3
ENSMUST00000038214.6
keratin 222
chr7_+_30493622 1.13 ENSMUST00000058280.6
ENSMUST00000133318.1
ENSMUST00000142575.1
ENSMUST00000131040.1
proline dehydrogenase (oxidase) 2
chr6_-_136941887 1.02 ENSMUST00000111891.1
Rho, GDP dissociation inhibitor (GDI) beta
chr6_-_128275577 1.01 ENSMUST00000130454.1
TEA domain family member 4
chr2_+_127854628 0.98 ENSMUST00000028859.1
acyl-Coenzyme A oxidase-like
chr5_-_43981757 0.94 ENSMUST00000061299.7
fibroblast growth factor binding protein 1
chr17_-_26099257 0.92 ENSMUST00000053575.3
predicted gene 8186
chr9_+_119063429 0.91 ENSMUST00000141185.1
ENSMUST00000126251.1
ENSMUST00000136561.1
villin-like
chr3_-_116253467 0.90 ENSMUST00000090473.5
G-protein coupled receptor 88
chr3_-_14778452 0.87 ENSMUST00000094365.4
carbonic anhydrase 1
chr16_+_45224315 0.87 ENSMUST00000102802.3
ENSMUST00000063654.4
B and T lymphocyte associated
chr10_+_116143881 0.86 ENSMUST00000105271.2
protein tyrosine phosphatase, receptor type, R
chr17_-_50094277 0.85 ENSMUST00000113195.1
raftlin lipid raft linker 1
chr18_+_50051702 0.85 ENSMUST00000134348.1
ENSMUST00000153873.2
tumor necrosis factor, alpha-induced protein 8
chr6_-_136941494 0.84 ENSMUST00000111892.1
Rho, GDP dissociation inhibitor (GDI) beta
chr15_-_36879816 0.83 ENSMUST00000100713.2
predicted gene 10384
chr8_-_106573461 0.82 ENSMUST00000073722.5
predicted pseudogene 10073
chr6_-_136941694 0.78 ENSMUST00000032344.5
Rho, GDP dissociation inhibitor (GDI) beta
chr4_+_145585166 0.78 ENSMUST00000105739.1
ENSMUST00000119718.1
predicted gene 13212
chr12_+_102128718 0.74 ENSMUST00000159329.1
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr1_-_4880669 0.73 ENSMUST00000078030.3
predicted gene 6104
chr14_+_61309753 0.72 ENSMUST00000055159.7
ADP-ribosylation factor-like 11
chr4_+_13743424 0.72 ENSMUST00000006761.3
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr3_-_17230976 0.68 ENSMUST00000177874.1
predicted gene 5283
chr11_+_31832660 0.67 ENSMUST00000132857.1
predicted gene 12107
chr18_-_23981555 0.65 ENSMUST00000115829.1
zinc finger and SCAN domain containing 30
chr18_+_11633276 0.63 ENSMUST00000115861.2
retinoblastoma binding protein 8
chr19_-_47692042 0.61 ENSMUST00000026045.7
ENSMUST00000086923.5
collagen, type XVII, alpha 1
chr17_-_81649607 0.59 ENSMUST00000163680.2
ENSMUST00000086538.3
ENSMUST00000163123.1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr2_+_110597298 0.58 ENSMUST00000045972.6
ENSMUST00000111026.2
solute carrier family 5 (sodium/glucose cotransporter), member 12
chr4_+_32623985 0.58 ENSMUST00000108178.1
caspase 8 associated protein 2
chr6_-_116716888 0.57 ENSMUST00000056623.6
transmembrane protein 72
chr10_-_127030813 0.57 ENSMUST00000040560.4
Ts translation elongation factor, mitochondrial
chr18_-_24603464 0.57 ENSMUST00000154205.1
solute carrier family 39 (metal ion transporter), member 6
chr17_-_56036546 0.56 ENSMUST00000003268.9
SH3-domain GRB2-like 1
chr10_+_79996479 0.55 ENSMUST00000132517.1
ATP-binding cassette, sub-family A (ABC1), member 7
chr6_+_30610984 0.55 ENSMUST00000062758.4
carboxypeptidase A5
chr13_-_105271039 0.53 ENSMUST00000069686.6
ring finger protein 180
chr10_-_127030789 0.53 ENSMUST00000120547.1
ENSMUST00000152054.1
Ts translation elongation factor, mitochondrial
chr8_-_24725762 0.52 ENSMUST00000171438.1
ENSMUST00000171611.1
ENSMUST00000033958.7
a disintegrin and metallopeptidase domain 3 (cyritestin)
chr19_+_5474681 0.52 ENSMUST00000165485.1
ENSMUST00000166253.1
ENSMUST00000167371.1
ENSMUST00000167855.1
ENSMUST00000070118.7
epidermal growth factor-containing fibulin-like extracellular matrix protein 2
chr16_-_29544852 0.52 ENSMUST00000039090.8
ATPase type 13A4
chr9_+_38877126 0.50 ENSMUST00000078289.2
olfactory receptor 926
chr12_-_55014329 0.49 ENSMUST00000172875.1
bromodomain adjacent to zinc finger domain 1A
chr8_+_57332111 0.49 ENSMUST00000181638.1
RIKEN cDNA 5033428I22 gene
chr18_+_53551594 0.49 ENSMUST00000115398.1
PR domain containing 6
chr18_-_24603791 0.46 ENSMUST00000070726.3
solute carrier family 39 (metal ion transporter), member 6
chr15_-_75905349 0.45 ENSMUST00000127550.1
eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
chrY_+_90785442 0.44 ENSMUST00000177591.1
ENSMUST00000177671.1
ENSMUST00000179077.1
erythroid differentiation regulator 1
chr13_+_120308146 0.43 ENSMUST00000081558.7
cDNA sequence BC147527
chrX_+_9885622 0.43 ENSMUST00000067529.2
ENSMUST00000086165.3
synaptotagmin-like 5
chr4_-_149126688 0.42 ENSMUST00000030815.2
cortistatin
chr2_+_163658370 0.41 ENSMUST00000164399.1
ENSMUST00000064703.6
ENSMUST00000099105.2
ENSMUST00000152418.1
ENSMUST00000126182.1
ENSMUST00000131228.1
protein kinase inhibitor, gamma
chr5_-_45169564 0.41 ENSMUST00000030975.5
RIKEN cDNA 4930435H24 gene
chr1_-_138175126 0.40 ENSMUST00000183301.1
protein tyrosine phosphatase, receptor type, C
chr3_+_24333046 0.40 ENSMUST00000077389.6
predicted gene 7536
chr19_+_23723279 0.39 ENSMUST00000067077.1
predicted gene 9938
chr10_+_116966274 0.38 ENSMUST00000033651.3
RIKEN cDNA D630029K05 gene
chr2_-_140671400 0.38 ENSMUST00000056760.3
fibronectin leucine rich transmembrane protein 3
chr6_-_119963733 0.38 ENSMUST00000161512.2
WNK lysine deficient protein kinase 1
chr19_-_55241236 0.38 ENSMUST00000069183.6
guanylate cyclase 2g
chr17_+_32468462 0.37 ENSMUST00000003413.6
cytochrome P450, family 4, subfamily f, polypeptide 39
chr1_-_138175283 0.37 ENSMUST00000182755.1
ENSMUST00000183262.1
ENSMUST00000027645.7
ENSMUST00000112036.2
ENSMUST00000182283.1
protein tyrosine phosphatase, receptor type, C
chr1_+_72284367 0.36 ENSMUST00000027380.5
ENSMUST00000141783.1
transmembrane protein 169
chr13_+_109926832 0.35 ENSMUST00000117420.1
phosphodiesterase 4D, cAMP specific
chr6_+_30611029 0.35 ENSMUST00000115138.1
carboxypeptidase A5
chr4_-_14621805 0.35 ENSMUST00000042221.7
solute carrier family 26, member 7
chr6_+_6248659 0.35 ENSMUST00000181633.1
ENSMUST00000176283.1
ENSMUST00000175814.1
ENSMUST00000181192.1
predicted gene 20619
chr14_-_75754475 0.34 ENSMUST00000049168.7
component of oligomeric golgi complex 3
chr13_-_105054895 0.32 ENSMUST00000063551.5
regulator of G-protein signalling 7 binding protein
chr18_+_59062462 0.31 ENSMUST00000058633.2
ENSMUST00000175897.1
ENSMUST00000118510.1
ENSMUST00000175830.1
RIKEN cDNA A730017C20 gene
chr4_-_147809788 0.31 ENSMUST00000105734.3
ENSMUST00000176201.1
predicted gene 13157
predicted gene 20707
chr19_-_38043559 0.30 ENSMUST00000041475.8
ENSMUST00000172095.2
myoferlin
chr16_+_92478743 0.30 ENSMUST00000160494.1
RIKEN cDNA 2410124H12 gene
chr11_-_82908360 0.30 ENSMUST00000103213.3
notchless homolog 1 (Drosophila)
chr8_+_34054622 0.29 ENSMUST00000149618.1
predicted gene 9951
chr10_+_23797052 0.29 ENSMUST00000133289.1
solute carrier family 18, subfamily B, member 1
chr1_-_138175238 0.28 ENSMUST00000182536.1
protein tyrosine phosphatase, receptor type, C
chr7_+_79273201 0.28 ENSMUST00000037315.6
abhydrolase domain containing 2
chr4_+_147132038 0.28 ENSMUST00000084149.3
predicted gene 13139
chr18_-_43477764 0.28 ENSMUST00000057110.9
eukaryotic translation initiation factor 3, subunit J2
chr4_+_66827545 0.27 ENSMUST00000048096.5
ENSMUST00000107365.2
toll-like receptor 4
chr19_+_34100943 0.26 ENSMUST00000025685.6
lipase, family member M
chr7_+_103928825 0.26 ENSMUST00000106863.1
olfactory receptor 631
chr8_+_121116163 0.26 ENSMUST00000054691.6
forkhead box C2
chr15_+_16778101 0.26 ENSMUST00000026432.6
cadherin 9
chrX_+_112093496 0.25 ENSMUST00000130247.2
ENSMUST00000038546.6
testis expressed gene 16
chr3_+_59925214 0.25 ENSMUST00000049476.2
RIKEN cDNA C130079G13 gene
chr9_+_53771499 0.25 ENSMUST00000048670.8
solute carrier family 35, member F2
chr2_-_85675173 0.25 ENSMUST00000099917.1
olfactory receptor 1006
chr4_-_129378116 0.25 ENSMUST00000030610.2
zinc finger and BTB domain containing 8a
chr2_-_113829069 0.25 ENSMUST00000024005.7
secretogranin V
chr6_-_141773810 0.24 ENSMUST00000148411.1
predicted gene 5724
chr19_-_39886730 0.22 ENSMUST00000168838.1
cytochrome P450, family 2, subfamily c, polypeptide 69
chr18_+_59062282 0.22 ENSMUST00000165666.2
RIKEN cDNA A730017C20 gene
chr6_-_122340525 0.21 ENSMUST00000112600.2
polyhomeotic-like 1 (Drosophila)
chr6_-_3399545 0.21 ENSMUST00000120087.3
sterile alpha motif domain containing 9-like
chr2_-_5895319 0.20 ENSMUST00000026926.4
ENSMUST00000102981.3
Sec61, alpha subunit 2 (S. cerevisiae)
chr15_-_99287174 0.20 ENSMUST00000109100.1
family with sequence similarity 186, member B
chr15_+_81744848 0.19 ENSMUST00000109554.1
zinc finger CCCH type containing 7B
chr15_+_82252397 0.19 ENSMUST00000136948.1
RIKEN cDNA 1500009C09 gene
chr3_-_88410295 0.19 ENSMUST00000056370.7
polyamine-modulated factor 1
chr19_-_32196393 0.18 ENSMUST00000151822.1
sphingomyelin synthase 1
chr13_-_21468474 0.17 ENSMUST00000068235.4
NFKB activating protein-like
chr8_+_92855319 0.17 ENSMUST00000046290.1
lysophosphatidylcholine acyltransferase 2
chr3_-_72967854 0.16 ENSMUST00000167334.1
sucrase isomaltase (alpha-glucosidase)
chr8_+_11713259 0.16 ENSMUST00000134409.1
RIKEN cDNA 1700128E19 gene
chr5_+_123907175 0.16 ENSMUST00000023869.8
density-regulated protein
chr10_-_130394241 0.15 ENSMUST00000094502.4
vomeronasal 2, receptor 84
chr1_-_34439672 0.15 ENSMUST00000042493.8
coiled-coil domain containing 115
chr18_+_55057557 0.14 ENSMUST00000181765.1
predicted gene 4221
chr1_+_24177610 0.14 ENSMUST00000054588.8
collagen, type IX, alpha 1
chr8_-_66486494 0.14 ENSMUST00000026681.5
translation machinery associated 16 homolog (S. cerevisiae)
chrX_+_101429555 0.14 ENSMUST00000033673.6
non-POU-domain-containing, octamer binding protein
chr7_-_100583072 0.13 ENSMUST00000152876.1
ENSMUST00000150042.1
mitochondrial ribosomal protein L48
chr5_+_138187485 0.13 ENSMUST00000110934.2
canopy 4 homolog (zebrafish)
chr6_-_137169710 0.13 ENSMUST00000117919.1
RAS-like, estrogen-regulated, growth-inhibitor
chr10_-_110000219 0.12 ENSMUST00000032719.7
neuron navigator 3
chrX_-_157415286 0.12 ENSMUST00000079945.4
ENSMUST00000138396.1
phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)
chr12_-_118966395 0.12 ENSMUST00000035515.4
ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr4_-_146909590 0.11 ENSMUST00000049821.3
predicted gene, 21411
chr4_+_146161909 0.11 ENSMUST00000131932.1
zinc finger protein 600
chr2_-_45112890 0.11 ENSMUST00000076836.6
zinc finger E-box binding homeobox 2
chrX_+_169685191 0.10 ENSMUST00000112104.1
ENSMUST00000112107.1
midline 1
chr8_-_105568298 0.10 ENSMUST00000005849.5
agouti related protein
chr1_+_133309778 0.10 ENSMUST00000094557.4
ENSMUST00000183457.1
ENSMUST00000183738.1
ENSMUST00000185157.1
ENSMUST00000184603.1
golgi transport 1 homolog A (S. cerevisiae)
KiSS-1 metastasis-suppressor
KISS1 isoform e
chr2_+_110721340 0.09 ENSMUST00000111016.2
mucin 15
chr2_-_80128834 0.09 ENSMUST00000102654.4
ENSMUST00000102655.3
phosphodiesterase 1A, calmodulin-dependent
chr11_-_107337556 0.09 ENSMUST00000040380.6
phosphatidylinositol transfer protein, cytoplasmic 1
chr8_+_107031218 0.08 ENSMUST00000034388.9
vacuolar protein sorting 4a (yeast)
chr2_+_151494182 0.08 ENSMUST00000089140.6
NSFL1 (p97) cofactor (p47)
chr15_-_8710409 0.08 ENSMUST00000157065.1
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr2_-_150255591 0.08 ENSMUST00000063463.5
predicted gene 21994
chr4_+_146610961 0.08 ENSMUST00000130825.1
predicted gene 13248
chr7_+_123123870 0.07 ENSMUST00000094053.5
trinucleotide repeat containing 6a
chr12_-_20900867 0.07 ENSMUST00000079237.5
zinc finger protein 125
chr10_-_87008015 0.07 ENSMUST00000035288.8
stabilin 2
chrX_-_8252304 0.07 ENSMUST00000115594.1
FtsJ homolog 1 (E. coli)
chr12_+_72536342 0.07 ENSMUST00000044352.6
pecanex-like 4 (Drosophila)
chr2_-_73580288 0.07 ENSMUST00000028515.3
cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)
chr1_-_127840290 0.06 ENSMUST00000061512.2
mitogen-activated protein kinase kinase kinase 19
chr1_-_187215454 0.06 ENSMUST00000183819.1
spermatogenesis associated 17
chr4_+_147305674 0.06 ENSMUST00000148762.3
predicted gene 13151
chrX_+_170009892 0.06 ENSMUST00000180251.1
predicted gene, 21887
chr18_+_23753708 0.06 ENSMUST00000115830.1
microtubule-associated protein, RP/EB family, member 2
chr19_-_23273893 0.06 ENSMUST00000087556.5
structural maintenance of chromosomes 5
chr9_+_113812547 0.05 ENSMUST00000166734.2
ENSMUST00000111838.2
ENSMUST00000163895.2
CLIP associating protein 2
chr7_-_38019505 0.05 ENSMUST00000085513.4
URI1, prefoldin-like chaperone
chr7_+_19119853 0.05 ENSMUST00000053109.3
F-box protein 46
chr10_+_116018213 0.04 ENSMUST00000063470.4
protein tyrosine phosphatase, receptor type, R
chr1_-_163085643 0.04 ENSMUST00000096608.4
maestro heat-like repeat family member 9
chr15_-_43477036 0.04 ENSMUST00000100683.2
predicted gene 10373
chr4_-_134245579 0.03 ENSMUST00000030644.7
zinc finger protein 593
chr6_+_24795824 0.03 ENSMUST00000031693.2
sperm adhesion molecule 1
chr1_-_150164943 0.03 ENSMUST00000181308.1
predicted gene, 26687
chr1_-_187215421 0.03 ENSMUST00000110945.3
ENSMUST00000183931.1
ENSMUST00000027908.6
spermatogenesis associated 17
chr9_-_118014160 0.02 ENSMUST00000111769.3
zinc finger, CW type with PWWP domain 2
chr4_+_30664587 0.01 ENSMUST00000128925.1
RIKEN cDNA 4930556G01 gene
chr1_+_34439851 0.01 ENSMUST00000027303.7
IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast)
chr1_+_190928492 0.01 ENSMUST00000066632.7
ENSMUST00000110899.1
angel homolog 2 (Drosophila)
chr12_-_11208948 0.01 ENSMUST00000049877.1
mesogenin 1
chr5_-_34660068 0.00 ENSMUST00000041364.9
NOP14 nucleolar protein
chr18_+_24603952 0.00 ENSMUST00000025120.6
elongator acetyltransferase complex subunit 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Nkx6-3_Dbx2_Barx2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 6.8 GO:0030916 otic vesicle formation(GO:0030916)
0.5 2.7 GO:0051661 maintenance of centrosome location(GO:0051661)
0.5 1.6 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.4 1.1 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.3 2.6 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.3 1.2 GO:0006780 uroporphyrinogen III biosynthetic process(GO:0006780)
0.3 1.4 GO:0010920 negative regulation of inositol phosphate biosynthetic process(GO:0010920) protein secretion by platelet(GO:0070560)
0.3 1.1 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.3 3.0 GO:0002826 negative regulation of T-helper 1 type immune response(GO:0002826)
0.2 2.4 GO:0016554 cytidine to uridine editing(GO:0016554)
0.2 4.3 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.2 1.4 GO:0019371 cyclooxygenase pathway(GO:0019371) maintenance of blood-brain barrier(GO:0035633)
0.2 0.9 GO:0061743 motor learning(GO:0061743)
0.2 1.1 GO:0002378 immunoglobulin biosynthetic process(GO:0002378) regulation of hematopoietic stem cell migration(GO:2000471) positive regulation of hematopoietic stem cell migration(GO:2000473)
0.2 1.0 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.2 0.6 GO:1901074 regulation of engulfment of apoptotic cell(GO:1901074)
0.2 1.3 GO:1990169 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.2 2.0 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.2 0.9 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.1 2.1 GO:0046884 follicle-stimulating hormone secretion(GO:0046884)
0.1 1.6 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719)
0.1 0.8 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.1 1.9 GO:1904659 glucose transmembrane transport(GO:1904659)
0.1 0.4 GO:0003345 proepicardium cell migration involved in pericardium morphogenesis(GO:0003345)
0.1 0.6 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.1 0.9 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.1 0.6 GO:1901678 iron coordination entity transport(GO:1901678)
0.1 1.5 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1 0.1 GO:0032278 positive regulation of gonadotropin secretion(GO:0032278) positive regulation of luteinizing hormone secretion(GO:0033686)
0.1 0.4 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.1 3.6 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.1 0.3 GO:0045362 interleukin-13 biosynthetic process(GO:0042231) regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.1 0.3 GO:0003275 apoptotic process involved in outflow tract morphogenesis(GO:0003275) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.1 0.6 GO:0098735 cellular response to caffeine(GO:0071313) positive regulation of the force of heart contraction(GO:0098735)
0.1 0.6 GO:0036337 Fas signaling pathway(GO:0036337)
0.1 0.9 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.1 4.3 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1 1.0 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.1 1.3 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 1.3 GO:0051764 actin crosslink formation(GO:0051764)
0.0 1.0 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.6 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.3 GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.0 0.2 GO:0002188 translation reinitiation(GO:0002188)
0.0 1.3 GO:0002820 negative regulation of adaptive immune response(GO:0002820)
0.0 0.5 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0 0.3 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.1 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.2 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.0 0.5 GO:0042415 norepinephrine metabolic process(GO:0042415)
0.0 0.7 GO:0097186 amelogenesis(GO:0097186)
0.0 0.3 GO:0032570 response to progesterone(GO:0032570)
0.0 0.4 GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.0 2.5 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.4 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.3 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.2 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.9 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.9 GO:0051693 actin filament capping(GO:0051693)
0.0 0.1 GO:0034093 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.0 0.2 GO:1905146 lysosomal protein catabolic process(GO:1905146)
0.0 0.4 GO:0045187 regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.0 0.5 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 0.4 GO:0009299 mRNA transcription(GO:0009299)
0.0 0.4 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.8 GO:0032611 interleukin-1 beta production(GO:0032611)
0.0 0.1 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.1 GO:0035372 protein localization to microtubule(GO:0035372)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.6 GO:0032437 cuticular plate(GO:0032437)
0.5 2.7 GO:0036449 microtubule minus-end(GO:0036449)
0.4 1.3 GO:0042585 germinal vesicle(GO:0042585)
0.4 1.6 GO:0060187 cell pole(GO:0060187)
0.3 4.3 GO:0042581 specific granule(GO:0042581)
0.1 0.5 GO:0008623 CHRAC(GO:0008623)
0.1 0.3 GO:0071007 U2-type catalytic step 2 spliceosome(GO:0071007)
0.1 0.4 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 0.9 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.1 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.0 1.3 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.3 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 1.5 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.3 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.2 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.2 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 4.5 GO:0000792 heterochromatin(GO:0000792)
0.0 0.6 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.3 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.6 GO:0001891 phagocytic cup(GO:0001891)
0.0 1.3 GO:0005871 kinesin complex(GO:0005871)
0.0 0.2 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.0 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.0 0.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.1 GO:0005796 Golgi lumen(GO:0005796)
0.0 1.4 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 1.4 GO:0032587 ruffle membrane(GO:0032587)
0.0 4.5 GO:0009897 external side of plasma membrane(GO:0009897)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 GO:0002113 interleukin-33 binding(GO:0002113)
0.4 2.4 GO:0004126 cytidine deaminase activity(GO:0004126)
0.3 2.6 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.2 1.5 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.2 1.9 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.2 1.2 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.2 0.6 GO:0090556 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.2 1.9 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 0.6 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
0.1 0.7 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 2.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.9 GO:0004064 arylesterase activity(GO:0004064)
0.1 1.0 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.1 0.6 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 0.6 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 1.6 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.2 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.1 0.3 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 1.1 GO:0071949 FAD binding(GO:0071949)
0.0 0.6 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 2.9 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.2 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.0 1.3 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 6.8 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 0.2 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.4 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 1.1 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 1.0 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.9 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 1.0 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.4 GO:0045499 chemorepellent activity(GO:0045499)
0.0 1.8 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.5 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.8 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 1.4 GO:0004601 peroxidase activity(GO:0004601)
0.0 0.5 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.4 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.3 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.8 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.4 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 4.2 GO:0005516 calmodulin binding(GO:0005516)
0.0 1.4 GO:0005179 hormone activity(GO:0005179)
0.0 0.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 4.2 GO:0045296 cadherin binding(GO:0045296)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 4.3 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 2.6 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 1.5 PID IGF1 PATHWAY IGF1 pathway
0.0 0.6 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.9 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 1.1 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.6 PID ATM PATHWAY ATM pathway
0.0 0.6 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.1 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.1 1.3 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 3.6 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 1.6 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.1 1.1 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 1.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 1.0 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.6 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 1.0 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.6 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 1.0 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.3 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.8 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.0 0.7 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation