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GSE58827: Dynamics of the Mouse Liver

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Results for Nr0b1

Z-value: 0.76

Motif logo

Transcription factors associated with Nr0b1

Gene Symbol Gene ID Gene Info
ENSMUSG00000025056.4 nuclear receptor subfamily 0, group B, member 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nr0b1mm10_v2_chrX_+_86191764_86191782-0.581.8e-04Click!

Activity profile of Nr0b1 motif

Sorted Z-values of Nr0b1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_88087802 5.33 ENSMUST00000113139.1
UDP glucuronosyltransferase 1 family, polypeptide A8
chr17_-_57059795 3.99 ENSMUST00000040280.7
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
chr16_-_20621255 2.78 ENSMUST00000052939.2
calcium/calmodulin-dependent protein kinase II inhibitor 2
chr4_+_148130883 2.29 ENSMUST00000084129.2
MAD2 mitotic arrest deficient-like 2
chr7_+_28180226 2.23 ENSMUST00000172467.1
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr7_+_28180272 2.18 ENSMUST00000173223.1
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr16_+_44173239 2.15 ENSMUST00000119746.1
predicted gene 608
chr13_-_29984219 1.98 ENSMUST00000146092.1
E2F transcription factor 3
chr9_+_80165013 1.63 ENSMUST00000035889.8
ENSMUST00000113268.1
myosin VI
chr9_+_80165079 1.62 ENSMUST00000184480.1
myosin VI
chr6_+_134830145 1.57 ENSMUST00000046303.5
cAMP responsive element binding protein-like 2
chr8_-_95434869 1.57 ENSMUST00000034249.6
gene trap locus 3
chr11_+_94328242 1.53 ENSMUST00000021227.5
ankyrin repeat domain 40
chr10_-_128589650 1.52 ENSMUST00000082059.6
v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
chr2_+_157279065 1.49 ENSMUST00000029171.5
ribophorin II
chr10_+_116301374 1.47 ENSMUST00000092167.5
protein tyrosine phosphatase, receptor type, B
chr10_-_127666673 1.41 ENSMUST00000026469.2
Ngfi-A binding protein 2
chr2_-_65238573 1.40 ENSMUST00000090896.3
ENSMUST00000155082.1
Cobl-like 1
chr1_+_140246216 1.38 ENSMUST00000119786.1
ENSMUST00000120796.1
ENSMUST00000060201.8
ENSMUST00000120709.1
potassium channel, subfamily T, member 2
chr2_+_4718145 1.36 ENSMUST00000056914.6
BEN domain containing 7
chr16_-_45844228 1.30 ENSMUST00000076333.5
pleckstrin homology-like domain, family B, member 2
chr16_-_45844303 1.29 ENSMUST00000036355.6
pleckstrin homology-like domain, family B, member 2
chr2_+_59160884 1.29 ENSMUST00000037903.8
plakophilin 4
chr2_+_157279026 1.28 ENSMUST00000116380.2
ribophorin II
chr6_+_134830216 1.27 ENSMUST00000111937.1
cAMP responsive element binding protein-like 2
chr17_-_26508463 1.25 ENSMUST00000025025.6
dual specificity phosphatase 1
chr4_-_118134869 1.17 ENSMUST00000097912.1
ENSMUST00000030263.2
ENSMUST00000106410.1
ST3 beta-galactoside alpha-2,3-sialyltransferase 3
chr9_+_57521232 1.14 ENSMUST00000000090.6
cytochrome c oxidase subunit Va
chr17_-_23745829 1.11 ENSMUST00000046525.8
kringle containing transmembrane protein 2
chr3_-_30509462 1.10 ENSMUST00000173899.1
MDS1 and EVI1 complex locus
chr11_+_94327984 1.07 ENSMUST00000107818.2
ENSMUST00000051221.6
ankyrin repeat domain 40
chr8_+_71371283 1.03 ENSMUST00000110051.1
ENSMUST00000002469.8
ENSMUST00000110052.1
occludin/ELL domain containing 1
chr2_-_80581234 1.02 ENSMUST00000028386.5
NCK-associated protein 1
chr2_-_65238625 1.01 ENSMUST00000112429.2
ENSMUST00000102726.1
ENSMUST00000112430.1
Cobl-like 1
chr13_-_64274879 1.00 ENSMUST00000109770.1
CDC14 cell division cycle 14B
chr2_-_80581380 0.97 ENSMUST00000111760.2
NCK-associated protein 1
chr11_+_23306884 0.97 ENSMUST00000180046.1
ubiquitin specific peptidase 34
chr3_-_139075178 0.97 ENSMUST00000098574.2
ENSMUST00000029796.6
RAP1, GTP-GDP dissociation stimulator 1
chr8_+_55940453 0.95 ENSMUST00000000275.7
glycine receptor, alpha 3 subunit
chr14_+_11553523 0.94 ENSMUST00000022264.6
protein tyrosine phosphatase, receptor type, G
chr7_-_80371197 0.92 ENSMUST00000098346.3
mannosidase 2, alpha 2
chr4_+_116221633 0.86 ENSMUST00000030464.7
phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55)
chrX_-_92016183 0.85 ENSMUST00000099471.2
ENSMUST00000072269.1
melanoma antigen, family B, 1
chr5_+_121711609 0.84 ENSMUST00000051950.7
ataxin 2
chr8_-_85080652 0.84 ENSMUST00000152785.1
WD repeat domain containing 83
chr8_-_85080679 0.78 ENSMUST00000093357.5
WD repeat domain containing 83
chr3_+_54156039 0.77 ENSMUST00000029311.6
transient receptor potential cation channel, subfamily C, member 4
chr18_+_35829798 0.77 ENSMUST00000060722.6
CXXC finger 5
chr13_-_31559333 0.75 ENSMUST00000170573.1
RIKEN cDNA A530084C06 gene
chr17_-_70851189 0.74 ENSMUST00000059775.8
TGFB-induced factor homeobox 1
chr10_+_39732099 0.73 ENSMUST00000019986.6
REV3-like, catalytic subunit of DNA polymerase zeta RAD54 like (S. cerevisiae)
chr3_-_107458895 0.70 ENSMUST00000009617.8
potassium voltage gated channel, Shaw-related subfamily, member 4
chr10_+_90829409 0.70 ENSMUST00000182202.1
ENSMUST00000182966.1
ankyrin repeat and sterile alpha motif domain containing 1B
chr4_+_116221590 0.70 ENSMUST00000147292.1
phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55)
chr10_-_81350389 0.67 ENSMUST00000020454.4
ENSMUST00000105324.2
ENSMUST00000154609.2
ENSMUST00000105323.1
high mobility group 20B
chr17_-_80728026 0.66 ENSMUST00000112389.2
ENSMUST00000025089.7
mitogen-activated protein kinase kinase kinase kinase 3
chr3_+_86224665 0.66 ENSMUST00000107635.1
LPS-responsive beige-like anchor
chr15_+_35371498 0.65 ENSMUST00000048646.7
vacuolar protein sorting 13B (yeast)
chr13_+_41249841 0.65 ENSMUST00000165561.2
small integral membrane protein 13
chr1_+_162570687 0.64 ENSMUST00000050010.4
ENSMUST00000150040.1
vesicle-associated membrane protein 4
chr17_-_84790517 0.63 ENSMUST00000112308.2
leucine-rich PPR-motif containing
chr5_-_99037035 0.63 ENSMUST00000031277.6
protein kinase, cGMP-dependent, type II
chr17_+_88530113 0.59 ENSMUST00000038551.6
protein phosphatase 1, regulatory subunit 21
chr4_-_138913915 0.57 ENSMUST00000097830.3
OTU domain containing 3
chr10_+_90829538 0.57 ENSMUST00000179694.2
ankyrin repeat and sterile alpha motif domain containing 1B
chr6_+_47454320 0.54 ENSMUST00000031697.8
cullin 1
chr2_-_144331695 0.54 ENSMUST00000103171.3
ovo-like 2 (Drosophila)
chr11_-_70687917 0.54 ENSMUST00000108545.2
ENSMUST00000120261.1
ENSMUST00000036299.7
ENSMUST00000119120.1
ENSMUST00000100933.3
calmodulin binding transcription activator 2
chr16_+_57121705 0.53 ENSMUST00000166897.1
translocase of outer mitochondrial membrane 70 homolog A (yeast)
chr5_-_99037342 0.51 ENSMUST00000161490.1
protein kinase, cGMP-dependent, type II
chr4_-_123750236 0.48 ENSMUST00000102636.3
akirin 1
chr10_+_127078886 0.48 ENSMUST00000039259.6
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr10_+_38965515 0.48 ENSMUST00000019992.5
laminin, alpha 4
chr4_-_135971894 0.45 ENSMUST00000105852.1
lysophospholipase 2
chr11_+_105181527 0.43 ENSMUST00000106941.2
tousled-like kinase 2 (Arabidopsis)
chr7_-_65371210 0.39 ENSMUST00000102592.3
tight junction protein 1
chr6_-_52191695 0.38 ENSMUST00000101395.2
homeobox A4
chr5_+_110230975 0.38 ENSMUST00000031474.7
ENSMUST00000086674.5
ankyrin repeat and LEM domain containing 2
chr15_-_38078842 0.38 ENSMUST00000110336.2
ubiquitin protein ligase E3 component n-recognin 5
chr11_+_23306910 0.37 ENSMUST00000137823.1
ubiquitin specific peptidase 34
chr11_+_105181793 0.37 ENSMUST00000092537.3
ENSMUST00000015107.6
ENSMUST00000145048.1
tousled-like kinase 2 (Arabidopsis)
chr13_+_94358943 0.35 ENSMUST00000022196.3
adaptor-related protein complex 3, beta 1 subunit
chr11_-_74723829 0.35 ENSMUST00000102520.2
platelet-activating factor acetylhydrolase, isoform 1b, subunit 1
chr4_-_11386394 0.34 ENSMUST00000155519.1
epithelial splicing regulatory protein 1
chr2_+_153842981 0.32 ENSMUST00000175856.1
EF-hand calcium binding domain 8
chr5_-_31193105 0.30 ENSMUST00000166769.1
eukaryotic translation initiation factor 2B, subunit 4 delta
chr2_+_30066419 0.30 ENSMUST00000067996.6
SET nuclear oncogene
chr1_+_59764264 0.28 ENSMUST00000087435.5
bone morphogenetic protein receptor, type II (serine/threonine kinase)
chr5_-_31193008 0.26 ENSMUST00000114605.1
ENSMUST00000114603.1
eukaryotic translation initiation factor 2B, subunit 4 delta
chr9_-_110117379 0.25 ENSMUST00000111991.2
ENSMUST00000149199.1
ENSMUST00000035056.7
ENSMUST00000148287.1
ENSMUST00000127744.1
DEAH (Asp-Glu-Ala-His) box polypeptide 30
chr4_-_132422484 0.24 ENSMUST00000102568.3
phosphatase and actin regulator 4
chr4_-_129696817 0.23 ENSMUST00000102588.3
transmembrane protein 39b
chr7_+_79500081 0.23 ENSMUST00000181511.2
ENSMUST00000182937.1
expressed sequence AI854517
chr18_+_80046854 0.16 ENSMUST00000070219.7
par-6 partitioning defective 6 homolog gamma (C. elegans)
chr12_+_49385174 0.16 ENSMUST00000110746.1
RIKEN cDNA 3110039M20 gene
chr13_-_106936907 0.15 ENSMUST00000080856.7
importin 11
chr2_+_85037448 0.15 ENSMUST00000168266.1
ENSMUST00000130729.1
structure specific recognition protein 1
chr3_-_123690806 0.15 ENSMUST00000154668.1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr1_+_42697146 0.13 ENSMUST00000054883.2
POU domain, class 3, transcription factor 3
chr9_-_109059711 0.10 ENSMUST00000061973.4
three prime repair exonuclease 1
chr18_-_10030017 0.09 ENSMUST00000116669.1
ENSMUST00000092096.6
ubiquitin specific peptidase 14
chr9_+_110333402 0.08 ENSMUST00000133114.1
ENSMUST00000125759.1
SREBF chaperone
chr4_+_116221689 0.07 ENSMUST00000106490.2
phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55)
chr2_-_144332146 0.04 ENSMUST00000037423.3
ovo-like 2 (Drosophila)
chr17_+_34898463 0.03 ENSMUST00000114033.2
ENSMUST00000078061.6
euchromatic histone lysine N-methyltransferase 2
chr4_+_99656299 0.03 ENSMUST00000087285.3
forkhead box D3
chr14_+_75845296 0.02 ENSMUST00000142061.1
tumor protein, translationally-controlled 1
chr2_-_157279519 0.01 ENSMUST00000143663.1
maestro heat-like repeat family member 8

Network of associatons between targets according to the STRING database.

First level regulatory network of Nr0b1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 4.0 GO:0097274 urea homeostasis(GO:0097274)
0.6 2.3 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.4 5.3 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.4 1.1 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.4 2.6 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.3 2.0 GO:0007354 zygotic determination of anterior/posterior axis, embryo(GO:0007354) mesodermal cell migration(GO:0008078) establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.2 0.7 GO:1904057 negative regulation of sensory perception of pain(GO:1904057)
0.2 3.2 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.2 2.0 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.2 1.4 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.2 0.6 GO:1990167 protein K6-linked deubiquitination(GO:0044313) protein K27-linked deubiquitination(GO:1990167)
0.2 0.6 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.1 0.4 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.1 0.4 GO:1902915 negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.1 0.7 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.1 0.4 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.1 1.0 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.1 1.3 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.1 0.9 GO:0006013 mannose metabolic process(GO:0006013)
0.1 0.3 GO:2000793 negative regulation of cell proliferation involved in heart morphogenesis(GO:2000137) cell proliferation involved in heart valve development(GO:2000793)
0.1 0.9 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.1 2.4 GO:0051639 actin filament network formation(GO:0051639)
0.1 1.5 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1 1.1 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.6 GO:0090003 regulation of Golgi to plasma membrane protein transport(GO:0042996) regulation of establishment of protein localization to plasma membrane(GO:0090003)
0.1 4.4 GO:0007520 myoblast fusion(GO:0007520)
0.1 0.5 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.1 1.0 GO:0032471 negative regulation of endoplasmic reticulum calcium ion concentration(GO:0032471) positive regulation of mitochondrial calcium ion concentration(GO:0051561)
0.1 1.1 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.1 0.6 GO:0060214 endocardium formation(GO:0060214)
0.1 0.3 GO:0051661 maintenance of centrosome location(GO:0051661)
0.1 0.8 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.1 0.6 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.0 0.2 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 2.8 GO:0046326 positive regulation of glucose import(GO:0046326)
0.0 0.7 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 1.3 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.7 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.8 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 0.8 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.0 3.9 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 1.6 GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 0.1 GO:0061386 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 1.3 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.4 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.1 GO:0072236 metanephric loop of Henle development(GO:0072236)
0.0 0.5 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.0 0.1 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 1.2 GO:0001706 endoderm formation(GO:0001706)
0.0 0.2 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.9 GO:1901998 toxin transport(GO:1901998)
0.0 0.5 GO:0003299 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.0 0.5 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 1.1 GO:0030279 negative regulation of ossification(GO:0030279)
0.0 0.0 GO:0071314 cellular response to cocaine(GO:0071314)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.0 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.2 2.8 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.2 0.7 GO:0002111 BRCA2-BRAF35 complex(GO:0002111)
0.2 2.6 GO:0045180 basal cortex(GO:0045180)
0.2 2.0 GO:0031209 SCAR complex(GO:0031209)
0.1 0.5 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 3.2 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.1 0.6 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.1 0.3 GO:0000235 astral microtubule(GO:0000235)
0.1 1.1 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 1.6 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 1.3 GO:0030057 desmosome(GO:0030057)
0.0 0.4 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.6 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.4 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.5 GO:0005605 basal lamina(GO:0005605)
0.0 1.5 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.9 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 2.1 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.9 GO:0034707 chloride channel complex(GO:0034707)
0.0 1.6 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.8 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 1.0 GO:0072686 mitotic spindle(GO:0072686)
0.0 2.0 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 1.1 GO:0000118 histone deacetylase complex(GO:0000118)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.8 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.4 1.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.3 4.0 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.3 1.2 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.2 1.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.2 2.8 GO:0004579 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.2 1.6 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.2 1.4 GO:0038132 neuregulin binding(GO:0038132)
0.1 5.3 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.9 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 3.0 GO:0008432 JUN kinase binding(GO:0008432)
0.1 0.5 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.1 0.9 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.1 4.4 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1 0.8 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 1.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 2.4 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.2 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.0 0.7 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.8 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.5 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 1.1 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.3 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.4 GO:0071253 connexin binding(GO:0071253)
0.0 0.1 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 0.7 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.4 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.7 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.3 GO:0036122 BMP binding(GO:0036122) BMP receptor activity(GO:0098821)
0.0 2.0 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.1 GO:0032405 MutLalpha complex binding(GO:0032405)
0.0 3.4 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 1.3 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 2.0 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 3.2 GO:0003774 motor activity(GO:0003774)
0.0 0.6 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.6 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 0.6 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.7 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.4 GO:0030742 GTP-dependent protein binding(GO:0030742)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.2 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 1.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.6 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.5 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 1.2 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.3 PID ALK2 PATHWAY ALK2 signaling events
0.0 1.1 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 2.0 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.5 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 1.0 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.5 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.4 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.7 PID TNF PATHWAY TNF receptor signaling pathway
0.0 1.0 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.3 PID REELIN PATHWAY Reelin signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 5.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.2 3.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.2 2.0 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.1 1.6 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 1.5 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 1.1 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 0.8 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.1 1.2 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.5 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.9 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 2.8 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.0 3.0 REACTOME DNA REPAIR Genes involved in DNA Repair
0.0 0.7 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.4 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 1.1 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.7 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.3 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.2 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.5 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import