Motif ID: Nr1h4

Z-value: 1.590


Transcription factors associated with Nr1h4:

Gene SymbolEntrez IDGene Name
Nr1h4 ENSMUSG00000047638.9 Nr1h4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr1h4mm10_v2_chr10_-_89506631_895066580.889.1e-13Click!


Activity profile for motif Nr1h4.

activity profile for motif Nr1h4


Sorted Z-values histogram for motif Nr1h4

Sorted Z-values for motif Nr1h4



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr1h4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_-_93079965 26.902 ENSMUST00000109582.1
Ces1b
carboxylesterase 1B
chr9_-_65422773 17.076 ENSMUST00000065894.5
Slc51b
solute carrier family 51, beta subunit
chr7_-_99695809 13.267 ENSMUST00000107086.2
Slco2b1
solute carrier organic anion transporter family, member 2b1
chr4_+_133553370 11.159 ENSMUST00000042706.2
Nr0b2
nuclear receptor subfamily 0, group B, member 2
chr7_-_105600103 10.758 ENSMUST00000033185.8
Hpx
hemopexin
chr11_+_72435511 10.601 ENSMUST00000076443.3
Ggt6
gamma-glutamyltransferase 6
chr11_+_72435565 10.214 ENSMUST00000100903.2
Ggt6
gamma-glutamyltransferase 6
chr11_+_72435534 10.071 ENSMUST00000108499.1
Ggt6
gamma-glutamyltransferase 6
chr2_-_69342600 10.026 ENSMUST00000102709.1
ENSMUST00000102710.3
ENSMUST00000180142.1
Abcb11


ATP-binding cassette, sub-family B (MDR/TAP), member 11


chr6_+_141629499 9.665 ENSMUST00000042812.6
Slco1b2
solute carrier organic anion transporter family, member 1b2
chr9_-_22002599 9.197 ENSMUST00000115336.2
ENSMUST00000044926.5
Ccdc151

coiled-coil domain containing 151

chr9_+_46268601 9.019 ENSMUST00000121598.1
Apoa5
apolipoprotein A-V
chr1_+_67123015 8.878 ENSMUST00000027144.7
Cps1
carbamoyl-phosphate synthetase 1
chr11_-_116198701 7.476 ENSMUST00000072948.4
Acox1
acyl-Coenzyme A oxidase 1, palmitoyl
chr15_-_82764176 7.165 ENSMUST00000055721.4
Cyp2d40
cytochrome P450, family 2, subfamily d, polypeptide 40
chr7_-_44670820 6.972 ENSMUST00000048102.7
Myh14
myosin, heavy polypeptide 14
chr17_-_74047850 6.544 ENSMUST00000043458.7
Srd5a2
steroid 5 alpha-reductase 2
chr11_-_116199040 6.530 ENSMUST00000066587.5
Acox1
acyl-Coenzyme A oxidase 1, palmitoyl
chr9_+_108662098 5.893 ENSMUST00000035222.5
Slc25a20
solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20
chr17_-_57228003 5.468 ENSMUST00000177046.1
ENSMUST00000024988.8
C3

complement component 3

chr9_+_44107286 5.420 ENSMUST00000152956.1
ENSMUST00000114815.1
C1qtnf5

C1q and tumor necrosis factor related protein 5

chr9_+_44107268 5.376 ENSMUST00000114821.2
ENSMUST00000114818.2
C1qtnf5

C1q and tumor necrosis factor related protein 5

chr17_-_32420965 5.282 ENSMUST00000170392.1
Pglyrp2
peptidoglycan recognition protein 2
chrX_-_139782353 5.252 ENSMUST00000101217.3
Ripply1
ripply1 homolog (zebrafish)
chr9_+_44107226 5.138 ENSMUST00000114816.1
C1qtnf5
C1q and tumor necrosis factor related protein 5
chr1_+_164151815 4.760 ENSMUST00000086040.5
F5
coagulation factor V
chr4_+_43632185 4.729 ENSMUST00000107874.2
Npr2
natriuretic peptide receptor 2
chr17_-_34862122 4.705 ENSMUST00000154526.1
Cfb
complement factor B
chr7_-_31055594 4.691 ENSMUST00000039909.6
Fxyd1
FXYD domain-containing ion transport regulator 1
chrX_-_52165252 4.589 ENSMUST00000033450.2
Gpc4
glypican 4
chr9_+_54538984 4.509 ENSMUST00000060242.5
ENSMUST00000118413.1
Sh2d7

SH2 domain containing 7

chr17_-_34862473 4.474 ENSMUST00000025229.4
ENSMUST00000176203.2
ENSMUST00000128767.1
Cfb


complement factor B


chr4_-_141618238 4.474 ENSMUST00000053263.8
Tmem82
transmembrane protein 82
chr12_-_98577940 4.462 ENSMUST00000110113.1
Kcnk10
potassium channel, subfamily K, member 10
chr5_-_116422858 4.366 ENSMUST00000036991.4
Hspb8
heat shock protein 8
chr9_+_108080436 4.358 ENSMUST00000035211.7
ENSMUST00000162886.1
Mst1

macrophage stimulating 1 (hepatocyte growth factor-like)

chr7_+_28180226 4.274 ENSMUST00000172467.1
Dyrk1b
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr17_-_83846769 4.083 ENSMUST00000000687.7
Haao
3-hydroxyanthranilate 3,4-dioxygenase
chr6_-_29380426 4.051 ENSMUST00000147483.2
Opn1sw
opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan)
chr11_+_97685903 3.727 ENSMUST00000107583.2
Cisd3
CDGSH iron sulfur domain 3
chr15_-_82394022 3.691 ENSMUST00000170255.1
Cyp2d11
cytochrome P450, family 2, subfamily d, polypeptide 11
chr6_-_59426279 3.655 ENSMUST00000051065.4
Gprin3
GPRIN family member 3
chr11_+_97685794 3.621 ENSMUST00000107584.1
ENSMUST00000107585.2
Cisd3

CDGSH iron sulfur domain 3

chr19_-_38124801 3.587 ENSMUST00000112335.2
Rbp4
retinol binding protein 4, plasma
chr7_+_44465391 3.577 ENSMUST00000035929.4
ENSMUST00000146128.1
Aspdh

aspartate dehydrogenase domain containing

chr9_-_106476372 3.488 ENSMUST00000123555.1
ENSMUST00000125850.1
Parp3

poly (ADP-ribose) polymerase family, member 3

chr13_+_24943144 3.399 ENSMUST00000021773.5
Gpld1
glycosylphosphatidylinositol specific phospholipase D1
chr11_+_101552135 3.372 ENSMUST00000103099.1
Nbr1
neighbor of Brca1 gene 1
chr16_-_23029062 3.351 ENSMUST00000115349.2
Kng2
kininogen 2
chr13_+_91741507 3.336 ENSMUST00000022120.4
Acot12
acyl-CoA thioesterase 12
chr14_-_30923754 3.327 ENSMUST00000006697.8
Itih3
inter-alpha trypsin inhibitor, heavy chain 3
chr13_+_40859768 3.299 ENSMUST00000110191.2
Gcnt2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr16_-_23029012 3.265 ENSMUST00000039338.6
Kng2
kininogen 2
chr16_-_23029080 3.262 ENSMUST00000100046.2
Kng2
kininogen 2
chr1_-_162859684 3.201 ENSMUST00000131058.1
Fmo1
flavin containing monooxygenase 1
chr10_+_4611971 3.126 ENSMUST00000105590.1
ENSMUST00000067086.7
Esr1

estrogen receptor 1 (alpha)

chr7_-_127345314 3.117 ENSMUST00000060783.5
Zfp768
zinc finger protein 768
chr10_+_43901782 3.061 ENSMUST00000054418.5
Rtn4ip1
reticulon 4 interacting protein 1
chr19_-_38125258 3.008 ENSMUST00000025951.6
Rbp4
retinol binding protein 4, plasma
chr10_+_116301374 2.953 ENSMUST00000092167.5
Ptprb
protein tyrosine phosphatase, receptor type, B
chr3_-_121171678 2.932 ENSMUST00000170781.1
ENSMUST00000039761.5
ENSMUST00000106467.1
ENSMUST00000106466.3
ENSMUST00000164925.2
Rwdd3




RWD domain containing 3




chr11_-_100704217 2.922 ENSMUST00000017974.6
Dhx58
DEXH (Asp-Glu-X-His) box polypeptide 58
chr17_-_87265866 2.879 ENSMUST00000145895.1
ENSMUST00000129616.1
ENSMUST00000155904.1
ENSMUST00000151155.1
ENSMUST00000144236.1
ENSMUST00000024963.3
Mcfd2





multiple coagulation factor deficiency 2





chr10_+_13966268 2.850 ENSMUST00000015645.4
Hivep2
human immunodeficiency virus type I enhancer binding protein 2
chr10_+_23894688 2.840 ENSMUST00000041416.7
Vnn1
vanin 1
chr10_-_78298162 2.807 ENSMUST00000105389.1
Agpat3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr10_-_81098874 2.729 ENSMUST00000117422.1
Creb3l3
cAMP responsive element binding protein 3-like 3
chr11_-_3931789 2.723 ENSMUST00000109992.1
ENSMUST00000109988.1
Tcn2

transcobalamin 2

chrX_-_18461371 2.627 ENSMUST00000044188.4
4930578C19Rik
RIKEN cDNA 4930578C19 gene
chr1_+_171225054 2.539 ENSMUST00000111321.1
ENSMUST00000005824.5
ENSMUST00000111320.1
ENSMUST00000111319.1
Apoa2



apolipoprotein A-II



chr15_-_82794236 2.529 ENSMUST00000006094.4
Cyp2d26
cytochrome P450, family 2, subfamily d, polypeptide 26
chr19_+_44992127 2.375 ENSMUST00000179305.1
Sema4g
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr4_-_124850652 2.367 ENSMUST00000125776.1
1110065P20Rik
RIKEN cDNA 1110065P20 gene
chr11_-_3931960 2.362 ENSMUST00000109990.1
ENSMUST00000020710.4
ENSMUST00000109989.3
ENSMUST00000109991.1
ENSMUST00000109993.2
Tcn2




transcobalamin 2




chr11_+_70519619 2.326 ENSMUST00000179000.1
Gltpd2
glycolipid transfer protein domain containing 2
chr14_-_30923547 2.259 ENSMUST00000170415.1
Itih3
inter-alpha trypsin inhibitor, heavy chain 3
chr7_-_29248375 2.175 ENSMUST00000032808.4
2200002D01Rik
RIKEN cDNA 2200002D01 gene
chr6_-_149101674 2.134 ENSMUST00000111557.1
Dennd5b
DENN/MADD domain containing 5B
chr6_-_124769548 2.079 ENSMUST00000149652.1
ENSMUST00000112476.1
ENSMUST00000004378.8
Eno2


enolase 2, gamma neuronal


chr11_+_75513540 2.074 ENSMUST00000042808.6
ENSMUST00000118243.1
Scarf1

scavenger receptor class F, member 1

chr17_+_25133385 2.020 ENSMUST00000040729.2
Clcn7
chloride channel 7
chr7_-_127936097 2.014 ENSMUST00000150591.1
Prss36
protease, serine, 36
chr17_-_57087729 2.009 ENSMUST00000071135.5
Tubb4a
tubulin, beta 4A class IVA
chr9_-_59353430 1.981 ENSMUST00000026265.6
Bbs4
Bardet-Biedl syndrome 4 (human)
chr11_+_21091291 1.896 ENSMUST00000093290.5
Peli1
pellino 1
chr9_-_50752348 1.889 ENSMUST00000042790.3
Hspb2
heat shock protein 2
chr2_+_177762898 1.869 ENSMUST00000119838.2
Gm14322
predicted gene 14322
chr16_-_20730544 1.844 ENSMUST00000076422.5
Thpo
thrombopoietin
chr2_-_130638094 1.839 ENSMUST00000089561.3
ENSMUST00000110260.1
Lzts3

leucine zipper, putative tumor suppressor family member 3

chr4_+_133039482 1.780 ENSMUST00000105914.1
Ahdc1
AT hook, DNA binding motif, containing 1
chr6_+_72414301 1.727 ENSMUST00000065906.7
Ggcx
gamma-glutamyl carboxylase
chrX_+_77511002 1.715 ENSMUST00000088217.5
Tbl1x
transducin (beta)-like 1 X-linked
chr5_-_147725988 1.685 ENSMUST00000110529.1
ENSMUST00000031652.3
ENSMUST00000031653.5
Flt1


FMS-like tyrosine kinase 1


chr15_-_77927728 1.661 ENSMUST00000174468.1
ENSMUST00000174529.1
ENSMUST00000173631.1
Txn2


thioredoxin 2


chr7_-_4971168 1.645 ENSMUST00000133272.1
Gm1078
predicted gene 1078
chr11_+_120442644 1.569 ENSMUST00000044105.8
Tspan10
tetraspanin 10
chr1_+_36511867 1.546 ENSMUST00000001166.7
ENSMUST00000097776.3
Cnnm3

cyclin M3

chr1_-_162813926 1.533 ENSMUST00000144916.1
ENSMUST00000140274.1
Fmo4

flavin containing monooxygenase 4

chr8_+_88521344 1.455 ENSMUST00000034086.5
Nkd1
naked cuticle 1 homolog (Drosophila)
chr4_-_15149755 1.441 ENSMUST00000108273.1
Necab1
N-terminal EF-hand calcium binding protein 1
chr3_+_137623672 1.437 ENSMUST00000053855.7
Ddit4l
DNA-damage-inducible transcript 4-like
chr2_+_122298898 1.427 ENSMUST00000028656.1
Duoxa2
dual oxidase maturation factor 2
chr4_+_53713998 1.425 ENSMUST00000128667.1
Fktn
fukutin
chrX_-_102644210 1.380 ENSMUST00000052012.7
ENSMUST00000043596.5
ENSMUST00000119229.1
ENSMUST00000122022.1
ENSMUST00000120270.1
ENSMUST00000113611.2
Phka1





phosphorylase kinase alpha 1





chr11_+_78037959 1.374 ENSMUST00000073660.6
Flot2
flotillin 2
chr11_+_101552188 1.374 ENSMUST00000147239.1
Nbr1
neighbor of Brca1 gene 1
chr1_-_171247096 1.372 ENSMUST00000013737.6
ENSMUST00000111318.1
Ndufs2

NADH dehydrogenase (ubiquinone) Fe-S protein 2

chrM_+_8600 1.348 ENSMUST00000082409.1
mt-Co3
mitochondrially encoded cytochrome c oxidase III
chr17_-_35909626 1.333 ENSMUST00000141132.1
Atat1
alpha tubulin acetyltransferase 1
chr7_-_105787567 1.322 ENSMUST00000144189.1
Dchs1
dachsous 1 (Drosophila)
chr7_-_4970961 1.294 ENSMUST00000144863.1
Gm1078
predicted gene 1078
chr18_-_61014199 1.259 ENSMUST00000025520.8
Slc6a7
solute carrier family 6 (neurotransmitter transporter, L-proline), member 7
chr8_+_104831572 1.211 ENSMUST00000059449.6
Ces2b
carboxyesterase 2B
chrX_+_20848543 1.194 ENSMUST00000001155.4
ENSMUST00000122312.1
ENSMUST00000120356.1
ENSMUST00000122850.1
Araf



v-raf murine sarcoma 3611 viral oncogene homolog



chr12_-_103631404 1.185 ENSMUST00000121625.1
ENSMUST00000044231.5
Serpina10

serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10

chr15_+_76380492 1.175 ENSMUST00000096385.4
ENSMUST00000160728.1
ENSMUST00000162319.1
Mroh1


maestro heat-like repeat family member 1


chr9_+_50752758 1.163 ENSMUST00000034562.7
Cryab
crystallin, alpha B
chr9_+_121710389 1.162 ENSMUST00000035113.9
Deb1
differentially expressed in B16F10 1
chr11_+_101552849 1.153 ENSMUST00000107213.1
ENSMUST00000107208.1
ENSMUST00000107212.1
ENSMUST00000127421.1
Nbr1



neighbor of Brca1 gene 1



chr6_-_86793522 1.152 ENSMUST00000001187.8
Anxa4
annexin A4
chr7_-_105787544 1.125 ENSMUST00000078482.5
ENSMUST00000154659.1
Dchs1

dachsous 1 (Drosophila)

chr14_-_26170283 1.125 ENSMUST00000100809.4
Plac9b
placenta specific 9b
chr9_-_20879718 1.120 ENSMUST00000043726.6
Angptl6
angiopoietin-like 6
chr17_+_24470393 1.098 ENSMUST00000053024.6
Pgp
phosphoglycolate phosphatase
chr10_-_67548944 1.091 ENSMUST00000075686.4
Ado
2-aminoethanethiol (cysteamine) dioxygenase
chr15_+_80287234 1.088 ENSMUST00000160424.1
Cacna1i
calcium channel, voltage-dependent, alpha 1I subunit
chr9_-_63377835 1.027 ENSMUST00000034920.9
Map2k5
mitogen-activated protein kinase kinase 5
chr3_+_94974728 1.025 ENSMUST00000072287.5
Pi4kb
phosphatidylinositol 4-kinase, catalytic, beta polypeptide
chr2_-_122298165 1.017 ENSMUST00000053734.5
Duox2
dual oxidase 2
chr9_+_22003035 1.004 ENSMUST00000115331.2
ENSMUST00000003493.7
Prkcsh

protein kinase C substrate 80K-H

chr1_-_157108632 0.995 ENSMUST00000118207.1
ENSMUST00000027884.6
ENSMUST00000121911.1
Tex35


testis expressed 35


chr4_-_42581621 0.941 ENSMUST00000178742.1
Gm10592
predicted gene 10592
chr7_+_138846579 0.925 ENSMUST00000155672.1
Ppp2r2d
protein phosphatase 2, regulatory subunit B, delta isoform
chr5_+_139907943 0.911 ENSMUST00000050519.6
Elfn1
leucine rich repeat and fibronectin type III, extracellular 1
chr11_-_102697710 0.904 ENSMUST00000164506.2
ENSMUST00000092569.6
Ccdc43

coiled-coil domain containing 43

chr7_+_16310412 0.902 ENSMUST00000136781.1
Bbc3
BCL2 binding component 3
chr10_-_89732253 0.880 ENSMUST00000020109.3
Actr6
ARP6 actin-related protein 6
chr17_+_24669730 0.831 ENSMUST00000047179.5
Zfp598
zinc finger protein 598
chr2_-_120353094 0.831 ENSMUST00000028752.7
ENSMUST00000102501.3
Vps39

vacuolar protein sorting 39 (yeast)

chr4_+_53440388 0.799 ENSMUST00000102911.3
ENSMUST00000107646.2
Slc44a1

solute carrier family 44, member 1

chr7_+_19176416 0.775 ENSMUST00000117338.1
Eml2
echinoderm microtubule associated protein like 2
chr1_-_51478390 0.775 ENSMUST00000027279.5
Nabp1
nucleic acid binding protein 1
chr1_+_152954966 0.760 ENSMUST00000043313.8
Nmnat2
nicotinamide nucleotide adenylyltransferase 2
chr5_-_129887442 0.732 ENSMUST00000094280.3
Chchd2
coiled-coil-helix-coiled-coil-helix domain containing 2
chr11_+_100334407 0.722 ENSMUST00000017309.1
Gast
gastrin
chr10_-_33995054 0.720 ENSMUST00000164429.1
Gm17567
predicted gene, 17567
chr9_+_56994932 0.718 ENSMUST00000034832.6
Ptpn9
protein tyrosine phosphatase, non-receptor type 9
chr4_-_135972620 0.704 ENSMUST00000067567.4
Lypla2
lysophospholipase 2
chr14_+_21500879 0.696 ENSMUST00000182964.1
Kat6b
K(lysine) acetyltransferase 6B
chr3_+_94974831 0.675 ENSMUST00000167008.1
ENSMUST00000107251.2
Pi4kb

phosphatidylinositol 4-kinase, catalytic, beta polypeptide

chr3_+_107090874 0.659 ENSMUST00000060946.3
ENSMUST00000182132.1
A930002I21Rik

RIKEN cDNA A930002I21 gene

chr4_+_147507600 0.650 ENSMUST00000063704.7
Gm13152
predicted gene 13152
chr11_+_88718442 0.646 ENSMUST00000138007.1
C030037D09Rik
RIKEN cDNA C030037D09 gene
chr15_+_85132080 0.645 ENSMUST00000023067.2
Ribc2
RIB43A domain with coiled-coils 2
chr10_+_80879720 0.643 ENSMUST00000105333.2
Tmprss9
transmembrane protease, serine 9
chr11_+_5955693 0.624 ENSMUST00000002818.8
Ykt6
YKT6 homolog (S. Cerevisiae)
chr17_-_5440229 0.599 ENSMUST00000005053.7
Tmem242
transmembrane protein 242
chr4_+_123904832 0.593 ENSMUST00000030400.7
Mycbp
c-myc binding protein
chr17_+_26781060 0.553 ENSMUST00000015725.8
ENSMUST00000135824.1
ENSMUST00000137989.1
Bnip1


BCL2/adenovirus E1B interacting protein 1


chr16_-_94370994 0.545 ENSMUST00000113914.1
ENSMUST00000113905.1
Pigp

phosphatidylinositol glycan anchor biosynthesis, class P

chr13_-_38960498 0.541 ENSMUST00000167513.1
Slc35b3
solute carrier family 35, member B3
chr18_+_42053692 0.528 ENSMUST00000074679.3
Sh3rf2
SH3 domain containing ring finger 2
chr7_+_126976338 0.520 ENSMUST00000032920.3
Cdipt
CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)
chr10_+_89686365 0.513 ENSMUST00000181598.1
1500026H17Rik
RIKEN cDNA 1500026H17 gene
chr11_+_73350839 0.475 ENSMUST00000120137.1
Olfr20
olfactory receptor 20
chr8_-_79248537 0.473 ENSMUST00000034109.4
1700011L22Rik
RIKEN cDNA 1700011L22 gene
chr19_-_24225015 0.473 ENSMUST00000099558.4
Tjp2
tight junction protein 2
chr16_-_10790902 0.466 ENSMUST00000050864.5
Prm3
protamine 3
chr4_-_123904826 0.447 ENSMUST00000181292.1
Gm26606
predicted gene, 26606
chr2_-_176149825 0.446 ENSMUST00000109049.3
ENSMUST00000179349.1
Gm2004

predicted gene 2004

chr8_+_92674289 0.435 ENSMUST00000034185.6
Irx6
Iroquois related homeobox 6 (Drosophila)
chr2_-_32775625 0.380 ENSMUST00000161958.1
Ttc16
tetratricopeptide repeat domain 16
chr13_+_37857934 0.378 ENSMUST00000138110.1
Rreb1
ras responsive element binding protein 1
chr9_-_22131801 0.359 ENSMUST00000069330.6
Acp5
acid phosphatase 5, tartrate resistant
chr18_+_42053648 0.343 ENSMUST00000072008.4
Sh3rf2
SH3 domain containing ring finger 2
chr2_-_152951688 0.330 ENSMUST00000109811.3
Dusp15
dual specificity phosphatase-like 15
chr7_-_47133684 0.320 ENSMUST00000102626.1
Ptpn5
protein tyrosine phosphatase, non-receptor type 5
chr2_-_152951547 0.314 ENSMUST00000037715.6
Dusp15
dual specificity phosphatase-like 15
chr2_+_176230177 0.312 ENSMUST00000135430.1
2210418O10Rik
RIKEN cDNA 2210418O10 gene
chr13_-_17993306 0.306 ENSMUST00000099735.4
Yae1d1
Yae1 domain containing 1
chr11_-_64079444 0.281 ENSMUST00000049091.8
Cox10
cytochrome c oxidase assembly protein 10
chr16_+_32431020 0.258 ENSMUST00000104893.2
Pcyt1a
phosphate cytidylyltransferase 1, choline, alpha isoform
chr4_-_135971894 0.221 ENSMUST00000105852.1
Lypla2
lysophospholipase 2
chr3_-_96293953 0.211 ENSMUST00000029748.3
Fcgr1
Fc receptor, IgG, high affinity I
chr1_-_63176653 0.200 ENSMUST00000027111.8
ENSMUST00000168099.2
Ndufs1

NADH dehydrogenase (ubiquinone) Fe-S protein 1

chr1_+_93006328 0.198 ENSMUST00000059676.4
Aqp12
aquaporin 12
chr11_+_85886360 0.195 ENSMUST00000108047.1
Tbx4
T-box 4
chr15_+_101473472 0.185 ENSMUST00000088049.3
Krt86
keratin 86
chr16_+_32430895 0.176 ENSMUST00000115137.1
ENSMUST00000079791.4
Pcyt1a

phosphate cytidylyltransferase 1, choline, alpha isoform

chr2_+_181497165 0.163 ENSMUST00000149163.1
ENSMUST00000000844.8
ENSMUST00000184849.1
ENSMUST00000108800.1
ENSMUST00000069712.2
Tpd52l2




tumor protein D52-like 2




chr4_-_133672601 0.156 ENSMUST00000062118.4
ENSMUST00000067902.6
Pigv

phosphatidylinositol glycan anchor biosynthesis, class V

chr1_+_172341197 0.137 ENSMUST00000056136.3
Kcnj10
potassium inwardly-rectifying channel, subfamily J, member 10
chr17_-_35910032 0.124 ENSMUST00000141662.1
ENSMUST00000056034.6
ENSMUST00000077494.6
ENSMUST00000149277.1
ENSMUST00000061052.5
Atat1




alpha tubulin acetyltransferase 1




chr7_-_47982296 0.121 ENSMUST00000087092.2
Mrgpra4
MAS-related GPR, member A4
chr11_-_115813621 0.112 ENSMUST00000041684.4
ENSMUST00000156812.1
Caskin2

CASK-interacting protein 2

chr16_-_94370647 0.084 ENSMUST00000113910.1
Pigp
phosphatidylinositol glycan anchor biosynthesis, class P
chr4_-_134186981 0.068 ENSMUST00000121566.1
Cep85
centrosomal protein 85
chr1_-_153808163 0.055 ENSMUST00000141249.1
Rgsl1
regulator of G-protein signaling like 1
chr10_-_43901712 0.046 ENSMUST00000020012.6
Qrsl1
glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1
chr15_+_86214431 0.046 ENSMUST00000063414.8
Tbc1d22a
TBC1 domain family, member 22a

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 13.3 GO:0071718 sodium-independent icosanoid transport(GO:0071718)
2.9 11.6 GO:0010901 regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
2.3 14.0 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
2.2 30.9 GO:0006751 glutathione catabolic process(GO:0006751)
1.9 17.1 GO:0060050 positive regulation of protein glycosylation(GO:0060050)
1.7 10.0 GO:0046618 drug export(GO:0046618)
1.6 6.6 GO:0048807 female genitalia morphogenesis(GO:0048807)
1.5 10.8 GO:0015886 heme transport(GO:0015886)
1.3 8.9 GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
1.2 3.5 GO:1990166 protein localization to site of double-strand break(GO:1990166)
1.1 3.4 GO:0006507 GPI anchor release(GO:0006507)
1.1 5.5 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
1.1 5.3 GO:0032824 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253) negative regulation of natural killer cell differentiation(GO:0032824) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
1.0 5.1 GO:0015889 cobalamin transport(GO:0015889)
1.0 5.9 GO:1902603 carnitine transmembrane transport(GO:1902603)
1.0 2.9 GO:1902071 positive regulation of cellular response to hypoxia(GO:1900039) regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
1.0 2.9 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534) positive regulation of MDA-5 signaling pathway(GO:1900245)
0.9 6.5 GO:0006702 androgen biosynthetic process(GO:0006702)
0.9 3.6 GO:0006742 NADP catabolic process(GO:0006742)
0.8 4.7 GO:1903275 positive regulation of sodium ion export(GO:1903275) positive regulation of sodium ion export from cell(GO:1903278)
0.7 9.7 GO:0006857 oligopeptide transport(GO:0006857)
0.7 9.2 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.6 2.4 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.6 1.7 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.6 9.2 GO:0036158 outer dynein arm assembly(GO:0036158)
0.6 1.7 GO:1901534 positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.5 3.3 GO:0036438 maintenance of lens transparency(GO:0036438)
0.5 3.1 GO:0060745 Sertoli cell proliferation(GO:0060011) prostate epithelial cord elongation(GO:0060523) mammary gland branching involved in pregnancy(GO:0060745)
0.5 4.1 GO:0046874 quinolinate metabolic process(GO:0046874)
0.5 1.5 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.5 4.7 GO:1900194 receptor guanylyl cyclase signaling pathway(GO:0007168) negative regulation of oocyte maturation(GO:1900194)
0.5 1.9 GO:0007525 somatic muscle development(GO:0007525)
0.5 1.4 GO:1903903 regulation of establishment of T cell polarity(GO:1903903)
0.4 4.4 GO:0060763 mammary duct terminal end bud growth(GO:0060763)
0.4 2.0 GO:0060295 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108) regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.4 4.1 GO:0018298 protein-chromophore linkage(GO:0018298)
0.4 1.1 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.4 5.3 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.3 1.0 GO:0070375 ERK5 cascade(GO:0070375)
0.3 1.8 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.3 0.8 GO:0097576 vacuole fusion(GO:0097576)
0.3 2.3 GO:0120009 intermembrane lipid transfer(GO:0120009)
0.3 1.0 GO:0048850 hypophysis morphogenesis(GO:0048850)
0.2 3.2 GO:0070995 NADPH oxidation(GO:0070995)
0.2 0.9 GO:1900739 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.2 1.5 GO:0042737 drug catabolic process(GO:0042737)
0.2 7.0 GO:0071625 vocalization behavior(GO:0071625)
0.2 1.5 GO:0038030 non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.2 0.8 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.2 2.7 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.2 13.4 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.2 2.8 GO:0033089 positive regulation of T cell differentiation in thymus(GO:0033089)
0.2 15.4 GO:0070206 protein trimerization(GO:0070206)
0.2 0.5 GO:1902559 3'-phosphoadenosine 5'-phosphosulfate transport(GO:0046963) 3'-phospho-5'-adenylyl sulfate transmembrane transport(GO:1902559)
0.2 0.5 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.2 2.1 GO:0048680 positive regulation of axon regeneration(GO:0048680)
0.2 9.9 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.2 1.2 GO:0007021 tubulin complex assembly(GO:0007021)
0.2 1.2 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.2 1.9 GO:0034141 positive regulation of toll-like receptor 3 signaling pathway(GO:0034141)
0.2 5.6 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.2 0.9 GO:0002084 protein depalmitoylation(GO:0002084)
0.2 0.8 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.1 1.4 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
0.1 2.8 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.1 1.4 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.1 1.3 GO:0035524 proline transmembrane transport(GO:0035524)
0.1 11.2 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.1 0.7 GO:0032094 response to food(GO:0032094)
0.1 3.3 GO:0006084 acetyl-CoA metabolic process(GO:0006084)
0.1 0.5 GO:2001205 negative regulation of osteoclast development(GO:2001205)
0.1 1.7 GO:0006662 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.1 5.9 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.1 4.3 GO:0060612 adipose tissue development(GO:0060612)
0.1 0.3 GO:2001025 positive regulation of response to drug(GO:2001025)
0.1 0.8 GO:0015871 choline transport(GO:0015871)
0.1 0.2 GO:0001788 antibody-dependent cellular cytotoxicity(GO:0001788)
0.1 0.6 GO:0031639 plasminogen activation(GO:0031639)
0.1 0.4 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.1 0.4 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.1 0.3 GO:0018343 protein farnesylation(GO:0018343)
0.1 0.7 GO:1900037 regulation of cellular response to hypoxia(GO:1900037)
0.0 0.9 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 1.0 GO:0006491 N-glycan processing(GO:0006491)
0.0 2.0 GO:0009268 response to pH(GO:0009268)
0.0 2.4 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.4 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.1 GO:0051933 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935) regulation of resting membrane potential(GO:0060075)
0.0 2.9 GO:0022904 respiratory electron transport chain(GO:0022904)
0.0 1.7 GO:0043627 response to estrogen(GO:0043627)
0.0 2.1 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.0 1.7 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 2.1 GO:0006096 glycolytic process(GO:0006096)
0.0 3.7 GO:0007596 blood coagulation(GO:0007596)
0.0 1.8 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 2.9 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 1.1 GO:0019228 neuronal action potential(GO:0019228)
0.0 0.8 GO:0006505 GPI anchor metabolic process(GO:0006505)
0.0 1.2 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 1.4 GO:0006073 glycogen metabolic process(GO:0005977) cellular glucan metabolic process(GO:0006073) glucan metabolic process(GO:0044042)
0.0 0.5 GO:0030261 chromosome condensation(GO:0030261)
0.0 0.8 GO:0000725 double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725)
0.0 0.1 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 7.0 GO:0097513 myosin II filament(GO:0097513)
0.8 10.0 GO:0046581 intercellular canaliculus(GO:0046581)
0.5 11.6 GO:0042627 chylomicron(GO:0042627)
0.4 3.1 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.4 6.5 GO:0070852 cell body fiber(GO:0070852)
0.3 3.4 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.3 2.0 GO:0033269 internode region of axon(GO:0033269)
0.2 2.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.2 4.8 GO:0031091 platelet alpha granule(GO:0031091)
0.2 35.3 GO:0072562 blood microparticle(GO:0072562)
0.2 1.4 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.2 4.7 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.2 2.0 GO:0034464 BBSome(GO:0034464)
0.2 8.9 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.2 13.3 GO:0009925 basal plasma membrane(GO:0009925)
0.2 14.0 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.2 1.5 GO:0097427 microtubule bundle(GO:0097427)
0.2 5.9 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.2 3.1 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.2 0.8 GO:0070876 SOSS complex(GO:0070876)
0.2 1.4 GO:0016600 flotillin complex(GO:0016600)
0.1 9.3 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 2.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 0.6 GO:0097441 basilar dendrite(GO:0097441)
0.1 3.5 GO:0090734 site of double-strand break(GO:0035861) site of DNA damage(GO:0090734)
0.1 1.2 GO:0097512 cardiac myofibril(GO:0097512)
0.1 0.8 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.1 9.2 GO:0036064 ciliary basal body(GO:0036064)
0.1 4.3 GO:0014704 intercalated disc(GO:0014704)
0.0 0.6 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 9.8 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.2 GO:0031501 mannosyltransferase complex(GO:0031501)
0.0 6.5 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.6 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.8 GO:0072686 mitotic spindle(GO:0072686)
0.0 1.7 GO:0005876 spindle microtubule(GO:0005876)
0.0 1.4 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.3 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.5 GO:0005921 gap junction(GO:0005921)
0.0 0.9 GO:0060076 excitatory synapse(GO:0060076)
0.0 0.6 GO:0031201 SNARE complex(GO:0031201)
0.0 1.0 GO:0005819 spindle(GO:0005819)
0.0 4.6 GO:0043235 receptor complex(GO:0043235)
0.0 1.2 GO:0000786 nucleosome(GO:0000786)
0.0 9.2 GO:0005740 mitochondrial envelope(GO:0005740)
0.0 0.5 GO:0030173 integral component of Golgi membrane(GO:0030173)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 8.9 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
2.7 10.8 GO:0015232 heme transporter activity(GO:0015232)
2.6 30.9 GO:0036374 glutathione hydrolase activity(GO:0036374)
2.3 14.0 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
1.6 6.5 GO:0047751 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) cholestenone 5-alpha-reductase activity(GO:0047751)
1.6 33.0 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
1.4 11.6 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
1.1 5.3 GO:0016019 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745) peptidoglycan receptor activity(GO:0016019)
1.0 3.1 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
1.0 5.9 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.9 4.7 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.8 3.3 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.7 3.3 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.6 2.8 GO:0034235 GPI anchor binding(GO:0034235)
0.6 5.1 GO:0031419 cobalamin binding(GO:0031419)
0.6 1.7 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.5 6.6 GO:0016918 retinal binding(GO:0016918)
0.5 4.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.5 4.7 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.4 11.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.4 3.5 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.3 3.4 GO:0004630 phospholipase D activity(GO:0004630)
0.3 7.0 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.3 1.7 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.3 1.1 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967)
0.3 2.3 GO:0120013 intermembrane lipid transfer activity(GO:0120013)
0.2 1.5 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.2 7.5 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.2 1.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.2 13.4 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.2 4.1 GO:0019825 oxygen binding(GO:0019825)
0.2 0.5 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.2 2.0 GO:0034452 dynactin binding(GO:0034452)
0.2 1.7 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.2 0.8 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.1 3.1 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 1.4 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 2.7 GO:0035497 cAMP response element binding(GO:0035497)
0.1 4.6 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 29.0 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.1 2.8 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 3.6 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.1 1.3 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.1 0.8 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.1 6.2 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.1 4.4 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 1.4 GO:0048038 quinone binding(GO:0048038)
0.1 2.0 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 4.7 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 2.1 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.1 16.5 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.1 1.0 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.1 11.2 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 0.6 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 1.6 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 1.1 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 6.5 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.5 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.2 GO:0019770 IgG receptor activity(GO:0019770)
0.0 2.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.4 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 1.8 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 1.7 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 1.2 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 2.6 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 1.2 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 1.4 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 1.8 GO:0043621 protein self-association(GO:0043621)
0.0 2.9 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.9 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 2.1 GO:0004743 phosphoglycerate kinase activity(GO:0004618) phosphoglycerate mutase activity(GO:0004619) pyruvate kinase activity(GO:0004743)
0.0 2.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.6 GO:0017171 serine-type peptidase activity(GO:0008236) serine hydrolase activity(GO:0017171)
0.0 1.7 GO:0008013 beta-catenin binding(GO:0008013)
0.0 1.0 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.8 GO:0043022 ribosome binding(GO:0043022)
0.0 0.7 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 1.5 GO:0030165 PDZ domain binding(GO:0030165)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 16.6 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.4 9.9 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.2 35.7 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 1.7 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.1 3.4 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 4.4 PID_AMB2_NEUTROPHILS_PATHWAY amb2 Integrin signaling
0.1 3.1 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.0 1.5 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 1.0 ST_GA12_PATHWAY G alpha 12 Pathway
0.0 6.8 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.2 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.0 1.4 SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES Genes related to the insulin receptor pathway
0.0 1.7 PID_AVB3_INTEGRIN_PATHWAY Integrins in angiogenesis
0.0 1.7 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 13.3 REACTOME_TRANSPORT_OF_ORGANIC_ANIONS Genes involved in Transport of organic anions
1.0 14.6 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade
0.6 14.0 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.6 10.0 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.5 4.1 REACTOME_OPSINS Genes involved in Opsins
0.5 6.5 REACTOME_ANDROGEN_BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.4 11.6 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.3 4.8 REACTOME_COMMON_PATHWAY Genes involved in Common Pathway
0.2 5.9 REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.2 4.1 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism
0.2 4.6 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.2 7.0 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.2 1.7 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.2 14.3 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 1.9 REACTOME_IRAK1_RECRUITS_IKK_COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 1.7 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 2.0 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 1.0 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 1.7 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.1 1.7 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 3.2 REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.1 1.4 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 2.9 REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.1 2.8 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.0 2.1 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.0 2.5 REACTOME_RIG_I_MDA5_MEDIATED_INDUCTION_OF_IFN_ALPHA_BETA_PATHWAYS Genes involved in RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
0.0 0.9 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.8 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.8 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.0 0.5 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 5.4 REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 1.6 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.0 1.1 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.1 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.5 REACTOME_GLYCEROPHOSPHOLIPID_BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis