Motif ID: Nr1i2

Z-value: 1.240


Transcription factors associated with Nr1i2:

Gene SymbolEntrez IDGene Name
Nr1i2 ENSMUSG00000022809.4 Nr1i2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr1i2mm10_v2_chr16_-_38294774_38294838-0.261.2e-01Click!


Activity profile for motif Nr1i2.

activity profile for motif Nr1i2


Sorted Z-values histogram for motif Nr1i2

Sorted Z-values for motif Nr1i2



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr1i2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_60582152 10.610 ENSMUST00000098047.2
Mup10
major urinary protein 10
chr4_-_61674094 10.316 ENSMUST00000098040.3
Mup18
major urinary protein 18
chr4_-_60421933 9.951 ENSMUST00000107506.2
ENSMUST00000122381.1
ENSMUST00000118759.1
ENSMUST00000122177.1
Mup9



major urinary protein 9



chr4_-_61303998 9.926 ENSMUST00000071005.8
ENSMUST00000075206.5
Mup14

major urinary protein 14

chr4_-_62087261 9.880 ENSMUST00000107488.3
ENSMUST00000107472.1
ENSMUST00000084531.4
Mup3


major urinary protein 3


chr4_-_60222580 9.450 ENSMUST00000095058.4
ENSMUST00000163931.1
Mup8

major urinary protein 8

chr4_-_61303802 9.397 ENSMUST00000125461.1
Mup14
major urinary protein 14
chr4_-_60662358 7.664 ENSMUST00000084544.4
ENSMUST00000098046.3
Mup11

major urinary protein 11

chr4_-_60139857 7.088 ENSMUST00000107490.4
ENSMUST00000074700.2
Mup2

major urinary protein 2

chr4_-_61835185 6.071 ENSMUST00000082287.2
Mup5
major urinary protein 5
chr19_+_37697792 5.604 ENSMUST00000025946.5
Cyp26a1
cytochrome P450, family 26, subfamily a, polypeptide 1
chr5_-_86926521 4.705 ENSMUST00000031183.2
Ugt2b1
UDP glucuronosyltransferase 2 family, polypeptide B1
chr17_-_32917320 4.632 ENSMUST00000179434.1
Cyp4f14
cytochrome P450, family 4, subfamily f, polypeptide 14
chr17_-_32917048 4.579 ENSMUST00000054174.7
Cyp4f14
cytochrome P450, family 4, subfamily f, polypeptide 14
chr2_-_25469742 4.415 ENSMUST00000114259.2
ENSMUST00000015234.6
Ptgds

prostaglandin D2 synthase (brain)

chr10_-_24101951 4.083 ENSMUST00000170267.1
Taar8c
trace amine-associated receptor 8C
chr4_-_59960659 3.577 ENSMUST00000075973.2
Mup4
major urinary protein 4
chr3_+_129532386 3.443 ENSMUST00000071402.2
Elovl6
ELOVL family member 6, elongation of long chain fatty acids (yeast)
chr6_-_138079916 3.155 ENSMUST00000171804.1
Slc15a5
solute carrier family 15, member 5
chr5_-_87254804 3.134 ENSMUST00000075858.3
Ugt2b37
UDP glucuronosyltransferase 2 family, polypeptide B37
chr1_+_166254095 2.909 ENSMUST00000111416.1
Ildr2
immunoglobulin-like domain containing receptor 2
chr1_-_139781236 2.742 ENSMUST00000027612.8
ENSMUST00000111989.2
ENSMUST00000111986.2
Gm4788


predicted gene 4788


chr5_-_77115145 2.725 ENSMUST00000081964.5
Hopx
HOP homeobox
chr1_+_127729405 2.718 ENSMUST00000038006.6
Acmsd
amino carboxymuconate semialdehyde decarboxylase
chr14_-_34355383 2.700 ENSMUST00000052126.5
Fam25c
family with sequence similarity 25, member C
chr7_+_27119909 2.642 ENSMUST00000003100.8
Cyp2f2
cytochrome P450, family 2, subfamily f, polypeptide 2
chr16_+_43363855 2.550 ENSMUST00000156367.1
Zbtb20
zinc finger and BTB domain containing 20
chr11_-_113709520 2.326 ENSMUST00000173655.1
ENSMUST00000100248.4
Cpsf4l

cleavage and polyadenylation specific factor 4-like

chr6_+_90333270 2.233 ENSMUST00000164761.1
ENSMUST00000046128.9
Uroc1

urocanase domain containing 1

chr1_-_130661613 2.186 ENSMUST00000027657.7
C4bp
complement component 4 binding protein
chr14_+_52824340 2.147 ENSMUST00000103648.2
Trav11d
T cell receptor alpha variable 11D
chr1_-_130661584 2.077 ENSMUST00000137276.2
C4bp
complement component 4 binding protein
chr9_-_98955302 2.044 ENSMUST00000181706.1
Foxl2os
forkhead box L2 opposite strand transcript
chr4_-_134372529 2.018 ENSMUST00000030643.2
Extl1
exostoses (multiple)-like 1
chr17_-_78985428 1.992 ENSMUST00000118991.1
Prkd3
protein kinase D3
chr16_+_11406618 1.989 ENSMUST00000122168.1
Snx29
sorting nexin 29
chr11_-_3722189 1.899 ENSMUST00000102950.3
ENSMUST00000101632.3
Osbp2

oxysterol binding protein 2

chr17_+_21691860 1.885 ENSMUST00000072133.4
Gm10226
predicted gene 10226
chr1_-_139560158 1.862 ENSMUST00000160423.1
ENSMUST00000023965.5
Cfhr1

complement factor H-related 1

chr8_+_76902277 1.824 ENSMUST00000109912.1
ENSMUST00000128862.1
ENSMUST00000109911.1
Nr3c2


nuclear receptor subfamily 3, group C, member 2


chr2_+_71981184 1.797 ENSMUST00000090826.5
ENSMUST00000102698.3
Rapgef4

Rap guanine nucleotide exchange factor (GEF) 4

chr10_+_96136603 1.783 ENSMUST00000074615.6
Gm5426
predicted pseudogene 5426
chr7_+_101394361 1.769 ENSMUST00000154239.1
ENSMUST00000098243.2
Arap1

ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1

chr11_-_70514608 1.717 ENSMUST00000021179.3
Vmo1
vitelline membrane outer layer 1 homolog (chicken)
chr14_-_118052235 1.676 ENSMUST00000022725.2
Dct
dopachrome tautomerase
chr2_+_177904285 1.643 ENSMUST00000099001.3
Gm14327
predicted gene 14327
chr8_+_119437118 1.629 ENSMUST00000152420.1
ENSMUST00000098365.3
Osgin1

oxidative stress induced growth inhibitor 1

chr16_+_91269759 1.616 ENSMUST00000056882.5
Olig1
oligodendrocyte transcription factor 1
chr1_+_88166004 1.613 ENSMUST00000097659.4
Ugt1a5
UDP glucuronosyltransferase 1 family, polypeptide A5
chr18_-_39490649 1.595 ENSMUST00000115567.1
Nr3c1
nuclear receptor subfamily 3, group C, member 1
chr15_+_99393610 1.579 ENSMUST00000159531.1
Tmbim6
transmembrane BAX inhibitor motif containing 6
chr1_-_183345296 1.568 ENSMUST00000109158.3
Mia3
melanoma inhibitory activity 3
chr5_-_66004278 1.548 ENSMUST00000067737.5
9130230L23Rik
RIKEN cDNA 9130230L23 gene
chr8_-_72435043 1.498 ENSMUST00000109974.1
Calr3
calreticulin 3
chr15_+_99393574 1.490 ENSMUST00000162624.1
Tmbim6
transmembrane BAX inhibitor motif containing 6
chr2_+_162987330 1.487 ENSMUST00000018012.7
Sgk2
serum/glucocorticoid regulated kinase 2
chr18_+_20247340 1.484 ENSMUST00000054128.6
Dsg1c
desmoglein 1 gamma
chr2_+_162987502 1.473 ENSMUST00000117123.1
Sgk2
serum/glucocorticoid regulated kinase 2
chr10_+_128194446 1.469 ENSMUST00000044776.6
Gls2
glutaminase 2 (liver, mitochondrial)
chr6_-_30304513 1.465 ENSMUST00000094543.2
ENSMUST00000102993.3
Ube2h

ubiquitin-conjugating enzyme E2H

chr2_-_25501717 1.447 ENSMUST00000015227.3
C8g
complement component 8, gamma polypeptide
chr4_+_42735545 1.418 ENSMUST00000068158.3
4930578G10Rik
RIKEN cDNA 4930578G10 gene
chr7_-_110061319 1.402 ENSMUST00000098110.2
AA474408
expressed sequence AA474408
chr2_+_109917639 1.386 ENSMUST00000046548.7
ENSMUST00000111037.2
Lgr4

leucine-rich repeat-containing G protein-coupled receptor 4

chr7_+_121707189 1.364 ENSMUST00000065310.2
1700069B07Rik
RIKEN cDNA 1700069B07 gene
chr13_-_71963713 1.343 ENSMUST00000077337.8
Irx1
Iroquois related homeobox 1 (Drosophila)
chr11_-_74925925 1.337 ENSMUST00000121738.1
Srr
serine racemase
chr6_-_97205549 1.333 ENSMUST00000164744.1
ENSMUST00000089287.5
Uba3

ubiquitin-like modifier activating enzyme 3

chr1_+_131797381 1.332 ENSMUST00000112393.2
ENSMUST00000048660.5
Pm20d1

peptidase M20 domain containing 1

chr15_+_7129557 1.327 ENSMUST00000067190.5
ENSMUST00000164529.1
Lifr

leukemia inhibitory factor receptor

chr17_-_46438471 1.322 ENSMUST00000087012.5
Slc22a7
solute carrier family 22 (organic anion transporter), member 7
chr14_+_17981633 1.305 ENSMUST00000022304.8
Thrb
thyroid hormone receptor beta
chr17_+_8165501 1.302 ENSMUST00000097419.3
ENSMUST00000024636.8
Fgfr1op

Fgfr1 oncogene partner

chr3_-_92083132 1.292 ENSMUST00000058150.6
Lor
loricrin
chr16_+_44173239 1.289 ENSMUST00000119746.1
Gm608
predicted gene 608
chr14_-_34522801 1.282 ENSMUST00000022325.1
9230112D13Rik
RIKEN cDNA 9230112D13 gene
chr9_+_65630552 1.279 ENSMUST00000055844.8
Rbpms2
RNA binding protein with multiple splicing 2
chr15_-_98221056 1.261 ENSMUST00000170618.1
ENSMUST00000141911.1
Olfr287

olfactory receptor 287

chr3_+_32736990 1.244 ENSMUST00000127477.1
ENSMUST00000121778.1
ENSMUST00000154257.1
Ndufb5


NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5


chr17_+_47436731 1.242 ENSMUST00000150819.2
AI661453
expressed sequence AI661453
chr6_+_48593883 1.242 ENSMUST00000154010.1
ENSMUST00000163452.1
ENSMUST00000118229.1
ENSMUST00000009420.8
Repin1



replication initiator 1



chr4_+_143349757 1.235 ENSMUST00000052458.2
Lrrc38
leucine rich repeat containing 38
chr7_+_24611314 1.223 ENSMUST00000073325.5
Phldb3
pleckstrin homology-like domain, family B, member 3
chr19_+_41029275 1.221 ENSMUST00000051806.4
ENSMUST00000112200.1
Dntt

deoxynucleotidyltransferase, terminal

chr7_-_139582790 1.193 ENSMUST00000106095.2
Nkx6-2
NK6 homeobox 2
chr18_-_61014199 1.190 ENSMUST00000025520.8
Slc6a7
solute carrier family 6 (neurotransmitter transporter, L-proline), member 7
chr1_-_136960427 1.188 ENSMUST00000027649.7
Nr5a2
nuclear receptor subfamily 5, group A, member 2
chrX_-_21089229 1.181 ENSMUST00000040667.6
Zfp300
zinc finger protein 300
chr11_+_76902152 1.180 ENSMUST00000102495.1
Tmigd1
transmembrane and immunoglobulin domain containing 1
chr9_+_21835506 1.179 ENSMUST00000058777.6
Gm6484
predicted gene 6484
chr16_+_43364145 1.173 ENSMUST00000148775.1
Zbtb20
zinc finger and BTB domain containing 20
chr19_-_47144174 1.167 ENSMUST00000111813.1
Calhm1
calcium homeostasis modulator 1
chr1_-_155527083 1.163 ENSMUST00000097531.2
Gm5532
predicted gene 5532
chr4_-_43653542 1.162 ENSMUST00000084646.4
Spag8
sperm associated antigen 8
chr2_-_71750083 1.160 ENSMUST00000180494.1
Gm17250
predicted gene, 17250
chr16_+_37868383 1.157 ENSMUST00000078717.6
Lrrc58
leucine rich repeat containing 58
chr18_-_3309858 1.139 ENSMUST00000144496.1
ENSMUST00000154715.1
Crem

cAMP responsive element modulator

chr10_-_41579207 1.137 ENSMUST00000095227.3
Ccdc162
coiled-coil domain containing 162
chr6_-_124917939 1.136 ENSMUST00000032216.6
Ptms
parathymosin
chr5_-_106696530 1.130 ENSMUST00000137285.1
ENSMUST00000124263.1
ENSMUST00000112695.1
ENSMUST00000155495.1
ENSMUST00000135108.1
Zfp644




zinc finger protein 644




chr10_+_44268328 1.129 ENSMUST00000039286.4
Atg5
autophagy related 5
chr2_-_176144697 1.128 ENSMUST00000178872.1
Gm2004
predicted gene 2004
chr10_+_128194631 1.127 ENSMUST00000123291.1
Gls2
glutaminase 2 (liver, mitochondrial)
chr7_-_4778141 1.123 ENSMUST00000094892.5
Il11
interleukin 11
chr10_+_81574699 1.117 ENSMUST00000131794.1
ENSMUST00000136341.1
Tle2

transducin-like enhancer of split 2, homolog of Drosophila E(spl)

chr17_+_43952999 1.115 ENSMUST00000177857.1
Rcan2
regulator of calcineurin 2
chr17_-_56121946 1.103 ENSMUST00000041357.7
Lrg1
leucine-rich alpha-2-glycoprotein 1
chr17_+_47436615 1.097 ENSMUST00000037701.6
AI661453
expressed sequence AI661453
chr14_+_61607455 1.095 ENSMUST00000051184.8
Kcnrg
potassium channel regulator
chr18_-_3281036 1.082 ENSMUST00000049942.6
ENSMUST00000139537.1
ENSMUST00000124747.1
Crem


cAMP responsive element modulator


chr7_-_141010759 1.073 ENSMUST00000026565.6
Ifitm3
interferon induced transmembrane protein 3
chr7_+_114718643 1.066 ENSMUST00000032902.4
ENSMUST00000182816.1
Calcb

calcitonin-related polypeptide, beta

chr4_+_136462250 1.062 ENSMUST00000084593.2
6030445D17Rik
RIKEN cDNA 6030445D17 gene
chr6_-_5256226 1.061 ENSMUST00000125686.1
ENSMUST00000031773.2
Pon3

paraoxonase 3

chr19_-_11081088 1.046 ENSMUST00000025636.6
Ms4a8a
membrane-spanning 4-domains, subfamily A, member 8A
chr9_-_22130598 1.043 ENSMUST00000115315.2
Acp5
acid phosphatase 5, tartrate resistant
chr4_-_96077509 1.032 ENSMUST00000097973.2
ENSMUST00000030305.6
ENSMUST00000107078.2
Cyp2j13


cytochrome P450, family 2, subfamily j, polypeptide 13


chr4_+_42735912 1.025 ENSMUST00000107984.1
4930578G10Rik
RIKEN cDNA 4930578G10 gene
chr6_-_11907419 1.023 ENSMUST00000031637.5
Ndufa4
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4
chr12_-_57546121 1.020 ENSMUST00000044380.6
Foxa1
forkhead box A1
chr1_+_59256906 1.017 ENSMUST00000160662.1
ENSMUST00000114248.2
Cdk15

cyclin-dependent kinase 15

chr11_+_49280150 1.011 ENSMUST00000078932.1
Olfr1393
olfactory receptor 1393
chr9_+_108339048 1.008 ENSMUST00000082429.5
Gpx1
glutathione peroxidase 1
chr11_-_26210553 0.998 ENSMUST00000101447.3
5730522E02Rik
RIKEN cDNA 5730522E02 gene
chr2_+_177768044 0.988 ENSMUST00000108942.3
Gm14322
predicted gene 14322
chr19_-_5845471 0.988 ENSMUST00000174287.1
ENSMUST00000173672.1
Neat1

nuclear paraspeckle assembly transcript 1 (non-protein coding)

chr4_+_124880899 0.983 ENSMUST00000059343.6
Epha10
Eph receptor A10
chr6_+_34709442 0.975 ENSMUST00000115021.1
Cald1
caldesmon 1
chr3_-_138131356 0.974 ENSMUST00000029805.8
Mttp
microsomal triglyceride transfer protein
chr4_-_129227883 0.974 ENSMUST00000106051.1
C77080
expressed sequence C77080
chr15_+_100353149 0.972 ENSMUST00000088142.5
ENSMUST00000176287.1
ENSMUST00000075675.5
Mettl7a2

AB099516
methyltransferase like 7A2

cDNA sequence AB099516
chr6_-_24527546 0.969 ENSMUST00000118558.1
Ndufa5
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
chr5_-_136565432 0.967 ENSMUST00000176172.1
Cux1
cut-like homeobox 1
chr9_+_31280525 0.964 ENSMUST00000117389.1
Prdm10
PR domain containing 10
chr18_-_3309723 0.955 ENSMUST00000136961.1
ENSMUST00000152108.1
Crem

cAMP responsive element modulator

chr19_-_44069736 0.954 ENSMUST00000172041.1
ENSMUST00000071698.6
ENSMUST00000112028.3
Erlin1


ER lipid raft associated 1


chr4_+_148140699 0.950 ENSMUST00000140049.1
ENSMUST00000105707.1
Mad2l2

MAD2 mitotic arrest deficient-like 2

chr10_-_75797528 0.947 ENSMUST00000120177.1
Gstt1
glutathione S-transferase, theta 1
chr1_-_157108632 0.940 ENSMUST00000118207.1
ENSMUST00000027884.6
ENSMUST00000121911.1
Tex35


testis expressed 35


chr9_+_75037838 0.935 ENSMUST00000169188.1
Arpp19
cAMP-regulated phosphoprotein 19
chr1_-_140183404 0.926 ENSMUST00000066859.6
ENSMUST00000111976.2
Cfh

complement component factor h

chr17_-_37023349 0.920 ENSMUST00000102665.4
Mog
myelin oligodendrocyte glycoprotein
chr3_+_98013503 0.919 ENSMUST00000079812.6
Notch2
notch 2
chr4_-_82705735 0.915 ENSMUST00000155821.1
Nfib
nuclear factor I/B
chr15_-_35938009 0.914 ENSMUST00000156915.1
Cox6c
cytochrome c oxidase subunit VIc
chr5_-_151190154 0.904 ENSMUST00000062015.8
ENSMUST00000110483.2
Stard13

StAR-related lipid transfer (START) domain containing 13

chr4_-_144721404 0.897 ENSMUST00000036876.7
Gm13178
predicted gene 13178
chr14_-_20794009 0.894 ENSMUST00000100837.3
ENSMUST00000080440.6
ENSMUST00000071816.6
Camk2g


calcium/calmodulin-dependent protein kinase II gamma


chr16_-_34095983 0.890 ENSMUST00000114973.1
ENSMUST00000114964.1
Kalrn

kalirin, RhoGEF kinase

chr11_+_53457209 0.887 ENSMUST00000018531.5
Shroom1
shroom family member 1
chr2_-_90580578 0.883 ENSMUST00000168621.2
Ptprj
protein tyrosine phosphatase, receptor type, J
chr17_+_32659410 0.883 ENSMUST00000165061.1
Cyp4f40
cytochrome P450, family 4, subfamily f, polypeptide 40
chr4_-_82505274 0.883 ENSMUST00000050872.8
ENSMUST00000064770.2
Nfib

nuclear factor I/B

chr3_+_122895072 0.881 ENSMUST00000023820.5
Fabp2
fatty acid binding protein 2, intestinal
chr17_+_43953191 0.879 ENSMUST00000044792.4
Rcan2
regulator of calcineurin 2
chr5_-_116422858 0.875 ENSMUST00000036991.4
Hspb8
heat shock protein 8
chr7_+_128003911 0.871 ENSMUST00000106248.1
Trim72
tripartite motif-containing 72
chr2_+_152105722 0.868 ENSMUST00000099225.2
Srxn1
sulfiredoxin 1 homolog (S. cerevisiae)
chr7_+_43712505 0.863 ENSMUST00000066834.6
Klk13
kallikrein related-peptidase 13
chr7_-_74554474 0.863 ENSMUST00000134539.1
ENSMUST00000026897.7
ENSMUST00000098371.2
Slco3a1


solute carrier organic anion transporter family, member 3a1


chr5_+_144255223 0.859 ENSMUST00000056578.6
Bri3
brain protein I3
chr6_-_59426279 0.856 ENSMUST00000051065.4
Gprin3
GPRIN family member 3
chr5_-_106696819 0.854 ENSMUST00000127434.1
ENSMUST00000112696.1
ENSMUST00000112698.1
Zfp644


zinc finger protein 644


chr2_+_175283298 0.840 ENSMUST00000098998.3
Gm14440
predicted gene 14440
chr6_+_48593927 0.831 ENSMUST00000135151.1
Repin1
replication initiator 1
chr2_+_80617045 0.829 ENSMUST00000028384.4
Dusp19
dual specificity phosphatase 19
chr1_+_9547948 0.826 ENSMUST00000144177.1
Adhfe1
alcohol dehydrogenase, iron containing, 1
chr9_+_75410145 0.825 ENSMUST00000180533.1
ENSMUST00000180574.1
4933433G15Rik

RIKEN cDNA 4933433G15 gene

chr11_-_82871133 0.822 ENSMUST00000071152.7
ENSMUST00000108173.3
Rffl

ring finger and FYVE like domain containing protein

chr7_-_126897424 0.817 ENSMUST00000120007.1
Tmem219
transmembrane protein 219
chr9_+_64235201 0.816 ENSMUST00000039011.3
Uchl4
ubiquitin carboxyl-terminal esterase L4
chr6_-_28447180 0.815 ENSMUST00000174194.1
Pax4
paired box gene 4
chr11_+_51261719 0.814 ENSMUST00000130641.1
Clk4
CDC like kinase 4
chr9_+_78051938 0.805 ENSMUST00000024104.7
Gcm1
glial cells missing homolog 1 (Drosophila)
chr9_-_89092835 0.804 ENSMUST00000167113.1
Trim43b
tripartite motif-containing 43B
chr6_+_21986887 0.803 ENSMUST00000151315.1
Cped1
cadherin-like and PC-esterase domain containing 1
chr8_-_13200576 0.802 ENSMUST00000165605.2
Grtp1
GH regulated TBC protein 1
chr2_-_136891363 0.800 ENSMUST00000028730.6
ENSMUST00000110089.2
Mkks

McKusick-Kaufman syndrome

chr5_+_30466044 0.800 ENSMUST00000031078.3
ENSMUST00000114743.1
1700001C02Rik

RIKEN cDNA 1700001C02 gene

chr14_+_103046977 0.790 ENSMUST00000022722.6
Irg1
immunoresponsive gene 1
chr5_-_48889531 0.788 ENSMUST00000176978.1
Kcnip4
Kv channel interacting protein 4
chr13_-_73328442 0.785 ENSMUST00000022097.5
Ndufs6
NADH dehydrogenase (ubiquinone) Fe-S protein 6
chr18_-_61036189 0.783 ENSMUST00000025521.8
Cdx1
caudal type homeobox 1
chr9_+_40187079 0.782 ENSMUST00000062229.5
Olfr986
olfactory receptor 986
chr11_+_98960412 0.780 ENSMUST00000107473.2
Rara
retinoic acid receptor, alpha
chr1_-_140183283 0.779 ENSMUST00000111977.1
Cfh
complement component factor h
chr5_+_119834663 0.772 ENSMUST00000018407.6
Tbx5
T-box 5
chr14_-_16243309 0.768 ENSMUST00000112625.1
Oxsm
3-oxoacyl-ACP synthase, mitochondrial
chr10_-_81600857 0.767 ENSMUST00000151858.1
ENSMUST00000142948.1
ENSMUST00000072020.2
Tle6


transducin-like enhancer of split 6, homolog of Drosophila E(spl)


chr1_+_6214627 0.765 ENSMUST00000027040.6
Rb1cc1
RB1-inducible coiled-coil 1
chr6_-_99632376 0.760 ENSMUST00000176255.1
Gm20696
predicted gene 20696
chr3_-_10335650 0.757 ENSMUST00000078748.3
Slc10a5
solute carrier family 10 (sodium/bile acid cotransporter family), member 5
chr7_+_105554360 0.754 ENSMUST00000046983.8
Smpd1
sphingomyelin phosphodiesterase 1, acid lysosomal
chr2_-_175133322 0.750 ENSMUST00000099029.3
Gm14399
predicted gene 14399
chr7_-_25390098 0.747 ENSMUST00000054301.7
Lipe
lipase, hormone sensitive
chr3_-_96220880 0.746 ENSMUST00000090782.3
Hist2h2ac
histone cluster 2, H2ac
chr10_+_94198955 0.746 ENSMUST00000020209.9
ENSMUST00000179990.1
Ndufa12

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12

chr8_+_46739745 0.742 ENSMUST00000034041.7
Irf2
interferon regulatory factor 2
chr7_+_105650813 0.736 ENSMUST00000145988.2
Dnhd1
dynein heavy chain domain 1
chr4_+_80910646 0.735 ENSMUST00000055922.3
Lurap1l
leucine rich adaptor protein 1-like

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.7 GO:0018879 biphenyl metabolic process(GO:0018879)
1.4 5.6 GO:0016103 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.9 3.6 GO:0042196 chlorinated hydrocarbon metabolic process(GO:0042196) halogenated hydrocarbon metabolic process(GO:0042197)
0.9 4.4 GO:1905937 negative regulation of germ cell proliferation(GO:1905937) negative regulation of male germ cell proliferation(GO:2000255)
0.8 5.0 GO:0036102 leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102)
0.6 7.0 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
0.6 3.1 GO:1904721 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.6 1.7 GO:0006583 melanin biosynthetic process from tyrosine(GO:0006583)
0.5 0.5 GO:0036482 neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036482) positive regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902958) regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903383) negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903384)
0.5 1.4 GO:0072204 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.5 1.4 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.5 1.8 GO:0031959 mineralocorticoid receptor signaling pathway(GO:0031959)
0.5 2.7 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.4 1.8 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.4 1.8 GO:1904457 positive regulation of neuronal action potential(GO:1904457)
0.4 2.2 GO:0006548 histidine catabolic process(GO:0006548)
0.4 0.9 GO:1901662 menaquinone metabolic process(GO:0009233) phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.4 2.6 GO:0006543 glutamine catabolic process(GO:0006543)
0.4 11.2 GO:0035634 response to stilbenoid(GO:0035634)
0.4 3.6 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.4 1.1 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.4 1.1 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.4 1.1 GO:0035973 aggrephagy(GO:0035973)
0.4 1.1 GO:0009698 phenylpropanoid metabolic process(GO:0009698) coumarin metabolic process(GO:0009804)
0.3 2.7 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.3 1.0 GO:0061144 alveolar secondary septum development(GO:0061144)
0.3 1.3 GO:0072272 proximal/distal pattern formation involved in metanephric nephron development(GO:0072272)
0.3 1.3 GO:0007113 endomitotic cell cycle(GO:0007113)
0.3 1.3 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.3 1.0 GO:0010949 negative regulation of intestinal phytosterol absorption(GO:0010949) negative regulation of intestinal cholesterol absorption(GO:0045796) intestinal phytosterol absorption(GO:0060752) negative regulation of intestinal lipid absorption(GO:1904730)
0.3 0.6 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.3 0.9 GO:0035622 intrahepatic bile duct development(GO:0035622) cholangiocyte proliferation(GO:1990705)
0.3 0.9 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.3 0.9 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.3 3.4 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.3 2.0 GO:0089700 protein kinase D signaling(GO:0089700)
0.3 1.3 GO:0070178 D-serine metabolic process(GO:0070178)
0.3 1.6 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.3 1.3 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.3 0.8 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.3 0.8 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.3 1.3 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.2 0.7 GO:0042758 long-chain fatty acid catabolic process(GO:0042758)
0.2 1.0 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.2 1.0 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.2 0.9 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.2 0.7 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534) positive regulation of MDA-5 signaling pathway(GO:1900245)
0.2 0.6 GO:1901052 sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
0.2 1.0 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.2 0.8 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.2 0.6 GO:2001200 positive regulation of dendritic cell differentiation(GO:2001200)
0.2 0.8 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.2 1.2 GO:0050916 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.2 2.3 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.2 0.6 GO:1904057 negative regulation of sensory perception of pain(GO:1904057)
0.2 0.6 GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.2 1.7 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.2 1.3 GO:2000275 regulation of oxidative phosphorylation uncoupler activity(GO:2000275)
0.2 0.7 GO:0046294 ethanol oxidation(GO:0006069) formaldehyde catabolic process(GO:0046294)
0.2 1.2 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.2 1.0 GO:0001980 regulation of systemic arterial blood pressure by ischemic conditions(GO:0001980)
0.2 1.2 GO:0061113 pancreas morphogenesis(GO:0061113)
0.2 0.7 GO:0070676 intralumenal vesicle formation(GO:0070676)
0.2 0.7 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.2 0.3 GO:0060599 lateral sprouting involved in mammary gland duct morphogenesis(GO:0060599)
0.2 1.6 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.2 0.8 GO:0060295 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108) regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.2 0.6 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
0.2 0.5 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.2 1.1 GO:0099645 protein localization to postsynaptic specialization membrane(GO:0099633) neurotransmitter receptor localization to postsynaptic specialization membrane(GO:0099645)
0.1 0.6 GO:0090126 protein complex assembly involved in synapse maturation(GO:0090126)
0.1 1.0 GO:0018158 protein oxidation(GO:0018158)
0.1 1.9 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.8 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 0.8 GO:0051790 short-chain fatty acid biosynthetic process(GO:0051790)
0.1 0.6 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 0.4 GO:1901738 regulation of vitamin A metabolic process(GO:1901738)
0.1 0.6 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 0.6 GO:0002803 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.1 0.6 GO:0021764 amygdala development(GO:0021764)
0.1 0.9 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.6 GO:2001205 negative regulation of osteoclast development(GO:2001205)
0.1 0.4 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.1 0.7 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
0.1 0.7 GO:0002084 protein depalmitoylation(GO:0002084)
0.1 1.6 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 2.0 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.1 0.3 GO:0044868 modulation by host of viral molecular function(GO:0044868) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.1 0.5 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.1 0.8 GO:0030242 autophagy of peroxisome(GO:0030242) peroxisome disassembly(GO:1905683)
0.1 0.7 GO:0006172 ADP biosynthetic process(GO:0006172)
0.1 1.2 GO:0035524 proline transmembrane transport(GO:0035524)
0.1 0.3 GO:1900157 regulation of bone mineralization involved in bone maturation(GO:1900157)
0.1 1.3 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.1 0.5 GO:0090168 Golgi reassembly(GO:0090168)
0.1 0.5 GO:0002176 male germ cell proliferation(GO:0002176)
0.1 0.3 GO:0015680 intracellular copper ion transport(GO:0015680)
0.1 0.6 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.1 0.4 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.1 0.9 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 3.7 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 0.2 GO:0032971 regulation of muscle filament sliding(GO:0032971)
0.1 1.1 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 0.2 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.1 0.4 GO:1903445 protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.1 0.5 GO:0038161 prolactin signaling pathway(GO:0038161)
0.1 0.6 GO:0015889 cobalamin transport(GO:0015889)
0.1 0.1 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.1 0.3 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.1 0.3 GO:0061623 galactose to glucose-1-phosphate metabolic process(GO:0061612) glycolytic process from galactose(GO:0061623)
0.1 0.9 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.1 0.7 GO:0043587 tongue morphogenesis(GO:0043587)
0.1 0.4 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.1 0.3 GO:0009946 proximal/distal axis specification(GO:0009946)
0.1 0.2 GO:0022615 protein to membrane docking(GO:0022615)
0.1 0.6 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.1 2.1 GO:2001273 regulation of glucose import in response to insulin stimulus(GO:2001273)
0.1 1.3 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.1 0.8 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 0.7 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.1 0.5 GO:0015886 heme transport(GO:0015886)
0.1 3.7 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 0.2 GO:0060466 activation of meiosis involved in egg activation(GO:0060466)
0.1 0.8 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.1 0.7 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.1 0.5 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.1 0.2 GO:0042823 vitamin B6 biosynthetic process(GO:0042819) pyridoxal phosphate biosynthetic process(GO:0042823)
0.1 0.3 GO:0090296 regulation of mitochondrial DNA replication(GO:0090296) negative regulation of mitochondrial DNA replication(GO:0090298)
0.1 0.2 GO:1902728 positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.1 1.3 GO:0050913 sensory perception of bitter taste(GO:0050913)
0.1 1.5 GO:0015732 prostaglandin transport(GO:0015732)
0.1 0.5 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.1 0.3 GO:0003273 cell migration involved in endocardial cushion formation(GO:0003273)
0.1 0.1 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.1 2.1 GO:0031424 keratinization(GO:0031424)
0.1 0.5 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1 0.3 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.1 2.6 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 0.3 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.1 0.4 GO:0070447 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.1 1.1 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.1 0.8 GO:0014807 regulation of somitogenesis(GO:0014807)
0.1 0.3 GO:0090235 regulation of metaphase plate congression(GO:0090235)
0.1 0.4 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.1 1.3 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.1 0.2 GO:0009624 response to nematode(GO:0009624)
0.1 3.0 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.1 0.2 GO:0031161 phosphatidylinositol catabolic process(GO:0031161)
0.1 0.6 GO:0021678 third ventricle development(GO:0021678)
0.1 0.9 GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.1 0.4 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.1 0.5 GO:0035902 response to immobilization stress(GO:0035902)
0.1 0.4 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.1 1.3 GO:0034453 microtubule anchoring(GO:0034453)
0.1 0.3 GO:0010640 regulation of platelet-derived growth factor receptor signaling pathway(GO:0010640)
0.1 0.5 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.1 1.8 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.1 3.2 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.1 1.7 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.1 1.2 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
0.1 1.1 GO:0035455 response to interferon-alpha(GO:0035455)
0.1 0.3 GO:0014719 skeletal muscle satellite cell activation(GO:0014719)
0.1 0.5 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.1 0.3 GO:0061525 hindgut development(GO:0061525)
0.0 0.4 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.7 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 0.5 GO:0043691 reverse cholesterol transport(GO:0043691)
0.0 0.3 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 0.7 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.8 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.4 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.6 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.0 0.6 GO:0006105 succinate metabolic process(GO:0006105)
0.0 1.0 GO:0030575 nuclear body organization(GO:0030575)
0.0 0.6 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.3 GO:1904861 excitatory synapse assembly(GO:1904861)
0.0 0.1 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.0 0.3 GO:0045794 negative regulation of cell volume(GO:0045794)
0.0 1.1 GO:0001881 receptor recycling(GO:0001881)
0.0 6.7 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.2 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.0 0.2 GO:0044351 macropinocytosis(GO:0044351)
0.0 1.1 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.8 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.8 GO:0050872 white fat cell differentiation(GO:0050872)
0.0 0.2 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 1.2 GO:0033198 response to ATP(GO:0033198)
0.0 0.4 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.7 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.4 GO:0070166 enamel mineralization(GO:0070166)
0.0 0.2 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.1 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.0 0.4 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.0 0.0 GO:0060336 negative regulation of response to interferon-gamma(GO:0060331) negative regulation of interferon-gamma-mediated signaling pathway(GO:0060336)
0.0 0.5 GO:0001709 cell fate determination(GO:0001709)
0.0 0.9 GO:0050892 intestinal absorption(GO:0050892)
0.0 0.2 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.1 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.0 GO:0071476 hypotonic response(GO:0006971) cellular hypotonic response(GO:0071476)
0.0 0.1 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.0 0.1 GO:0014036 neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036)
0.0 0.7 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.2 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.3 GO:0007320 insemination(GO:0007320)
0.0 0.3 GO:1903351 response to dopamine(GO:1903350) cellular response to dopamine(GO:1903351)
0.0 3.0 GO:0032092 positive regulation of protein binding(GO:0032092)
0.0 0.1 GO:0071798 response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.0 0.3 GO:0043649 dicarboxylic acid catabolic process(GO:0043649)
0.0 0.5 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.0 0.5 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.0 0.3 GO:0071361 cellular response to ethanol(GO:0071361)
0.0 0.4 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.4 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.0 0.9 GO:0042775 mitochondrial ATP synthesis coupled electron transport(GO:0042775)
0.0 0.1 GO:0060613 fat pad development(GO:0060613)
0.0 4.0 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.4 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.3 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.4 GO:0070842 aggresome assembly(GO:0070842)
0.0 0.6 GO:0097503 sialylation(GO:0097503)
0.0 0.9 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.6 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.3 GO:1902004 positive regulation of amyloid-beta formation(GO:1902004)
0.0 0.1 GO:0071321 cellular response to cGMP(GO:0071321)
0.0 0.2 GO:0010991 regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.1 GO:0060005 vestibular reflex(GO:0060005)
0.0 1.1 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.2 GO:0070508 sterol import(GO:0035376) cholesterol import(GO:0070508)
0.0 0.6 GO:0071677 positive regulation of mononuclear cell migration(GO:0071677)
0.0 0.5 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.9 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.3 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.2 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.5 GO:0070932 histone H3 deacetylation(GO:0070932)
0.0 2.3 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 0.3 GO:0034205 amyloid-beta formation(GO:0034205)
0.0 0.4 GO:0034643 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.0 0.1 GO:0033082 regulation of extrathymic T cell differentiation(GO:0033082)
0.0 0.2 GO:0003433 growth plate cartilage chondrocyte differentiation(GO:0003418) chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.0 0.1 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.0 2.1 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.4 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.6 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.0 0.5 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.8 GO:0006818 hydrogen transport(GO:0006818)
0.0 0.4 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.4 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.0 0.5 GO:0006855 drug transmembrane transport(GO:0006855)
0.0 0.1 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.2 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.0 0.5 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.2 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 1.5 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.2 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.2 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.2 GO:0015701 bicarbonate transport(GO:0015701)
0.0 1.5 GO:0007606 sensory perception of chemical stimulus(GO:0007606)
0.0 0.1 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.2 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.5 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 0.0 GO:0046881 positive regulation of luteinizing hormone secretion(GO:0033686) positive regulation of follicle-stimulating hormone secretion(GO:0046881)
0.0 0.2 GO:0006972 hyperosmotic response(GO:0006972)
0.0 0.2 GO:0001502 cartilage condensation(GO:0001502)
0.0 0.1 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.1 GO:0008228 opsonization(GO:0008228)
0.0 0.2 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 1.2 GO:0006342 chromatin silencing(GO:0006342)
0.0 0.8 GO:0070206 protein trimerization(GO:0070206)
0.0 0.7 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0 1.0 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.1 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.0 0.1 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.0 0.2 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0 0.3 GO:0032410 negative regulation of transporter activity(GO:0032410)
0.0 0.1 GO:0033227 dsRNA transport(GO:0033227)
0.0 0.1 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 0.1 GO:0002024 diet induced thermogenesis(GO:0002024)
0.0 0.3 GO:0019228 neuronal action potential(GO:0019228)
0.0 0.7 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.0 GO:0075733 intracellular transport of virus(GO:0075733) regulation of intracellular transport of viral material(GO:1901252)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.4 1.8 GO:0044316 cone cell pedicle(GO:0044316)
0.3 1.0 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.3 1.3 GO:0036019 endolysosome(GO:0036019)
0.3 1.1 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.3 0.8 GO:0018444 translation release factor complex(GO:0018444)
0.2 0.7 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.2 0.8 GO:1902636 kinociliary basal body(GO:1902636)
0.2 1.6 GO:0097413 Lewy body(GO:0097413)
0.2 1.0 GO:1990584 cardiac Troponin complex(GO:1990584)
0.2 1.0 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.2 0.6 GO:0097209 epidermal lamellar body(GO:0097209)
0.1 1.0 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 1.4 GO:0005579 membrane attack complex(GO:0005579)
0.1 0.6 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1 0.6 GO:0043202 lysosomal lumen(GO:0043202)
0.1 0.5 GO:0070552 BRISC complex(GO:0070552)
0.1 0.5 GO:0099053 activating signal cointegrator 1 complex(GO:0099053)
0.1 5.1 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 2.3 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 1.1 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 0.3 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.1 0.4 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
0.1 0.8 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.1 0.9 GO:0000815 ESCRT III complex(GO:0000815)
0.1 0.4 GO:0005914 spot adherens junction(GO:0005914)
0.1 1.8 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 0.7 GO:0005787 signal peptidase complex(GO:0005787)
0.1 0.3 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.1 2.9 GO:0001533 cornified envelope(GO:0001533)
0.1 0.6 GO:0042382 paraspeckles(GO:0042382)
0.1 0.7 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.1 0.9 GO:0045179 apical cortex(GO:0045179)
0.1 1.5 GO:0030057 desmosome(GO:0030057)
0.1 0.5 GO:0031415 NatA complex(GO:0031415)
0.1 0.9 GO:0042599 lamellar body(GO:0042599)
0.1 0.5 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 0.6 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 6.3 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 1.7 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 0.7 GO:0001520 outer dense fiber(GO:0001520)
0.1 0.1 GO:0098855 HCN channel complex(GO:0098855)
0.1 2.3 GO:0097440 apical dendrite(GO:0097440)
0.0 0.5 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 1.5 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.0 1.7 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 4.1 GO:0005811 lipid droplet(GO:0005811)
0.0 2.0 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.5 GO:0097449 astrocyte projection(GO:0097449)
0.0 0.3 GO:0099061 integral component of postsynaptic density membrane(GO:0099061) intrinsic component of postsynaptic density membrane(GO:0099146)
0.0 0.3 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.5 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.6 GO:0071819 SAGA complex(GO:0000124) DUBm complex(GO:0071819)
0.0 0.3 GO:0071664 beta-catenin-TCF7L2 complex(GO:0070369) catenin-TCF7L2 complex(GO:0071664)
0.0 0.7 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.6 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.1 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.0 0.3 GO:0089701 U2AF(GO:0089701)
0.0 0.3 GO:0036128 CatSper complex(GO:0036128)
0.0 0.1 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 3.6 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.3 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.6 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.0 1.0 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.2 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.1 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.7 GO:0001891 phagocytic cup(GO:0001891)
0.0 1.2 GO:0000791 euchromatin(GO:0000791)
0.0 1.2 GO:0060076 excitatory synapse(GO:0060076)
0.0 0.6 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.0 0.5 GO:0045120 pronucleus(GO:0045120)
0.0 1.1 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.4 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.2 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 4.2 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.7 GO:0043198 dendritic shaft(GO:0043198)
0.0 1.0 GO:0001772 immunological synapse(GO:0001772)
0.0 0.2 GO:0043083 synaptic cleft(GO:0043083)
0.0 7.1 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 0.3 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 1.2 GO:0000786 nucleosome(GO:0000786)
0.0 0.5 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.6 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 2.6 GO:0043197 dendritic spine(GO:0043197)
0.0 0.1 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 0.1 GO:0032021 NELF complex(GO:0032021)
0.0 1.1 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.2 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.0 GO:0044194 cytolytic granule(GO:0044194)
0.0 0.3 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.2 GO:0051233 spindle midzone(GO:0051233)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 9.2 GO:0052870 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871)
1.9 5.6 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
1.1 4.4 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.7 2.0 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.6 1.8 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
0.6 20.6 GO:0005550 pheromone binding(GO:0005550)
0.5 1.6 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.5 3.1 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.4 1.3 GO:0036361 racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.4 1.3 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.4 2.6 GO:0004359 glutaminase activity(GO:0004359)
0.4 4.3 GO:0001594 trace-amine receptor activity(GO:0001594)
0.4 1.1 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.4 1.1 GO:0004063 aryldialkylphosphatase activity(GO:0004063)
0.3 2.0 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.3 2.3 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.3 1.6 GO:0038049 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.3 0.9 GO:0019120 hydrolase activity, acting on acid halide bonds(GO:0016824) hydrolase activity, acting on acid halide bonds, in C-halide compounds(GO:0019120) alkylhalidase activity(GO:0047651)
0.3 1.2 GO:0099103 channel activator activity(GO:0099103) potassium channel activator activity(GO:0099104)
0.3 3.4 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.3 2.0 GO:0015198 oligopeptide transporter activity(GO:0015198)
0.3 0.8 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.3 9.5 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.3 1.3 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.3 1.3 GO:0030280 structural constituent of epidermis(GO:0030280)
0.3 1.5 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.2 1.7 GO:0001851 complement component C3b binding(GO:0001851)
0.2 0.6 GO:0008480 sarcosine dehydrogenase activity(GO:0008480)
0.2 0.8 GO:0016918 retinal binding(GO:0016918)
0.2 0.8 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
0.2 1.3 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.2 0.9 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.2 1.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.2 1.1 GO:0019776 Atg8 ligase activity(GO:0019776)
0.2 0.9 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.2 0.3 GO:0043682 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
0.1 0.7 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.1 1.0 GO:0030172 troponin C binding(GO:0030172)
0.1 0.7 GO:0070404 testosterone dehydrogenase (NAD+) activity(GO:0047035) NADH binding(GO:0070404)
0.1 0.8 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 3.1 GO:0017081 chloride channel regulator activity(GO:0017081)
0.1 0.6 GO:0004348 glucosylceramidase activity(GO:0004348)
0.1 1.6 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.1 1.4 GO:0019841 retinol binding(GO:0019841)
0.1 2.6 GO:0019825 oxygen binding(GO:0019825)
0.1 0.5 GO:0015232 heme transporter activity(GO:0015232)
0.1 0.5 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1 0.3 GO:0050479 glyceryl-ether monooxygenase activity(GO:0050479)
0.1 2.2 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.1 0.4 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 1.8 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.1 0.3 GO:0005110 frizzled-2 binding(GO:0005110)
0.1 1.2 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.1 0.8 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 1.0 GO:0003993 acid phosphatase activity(GO:0003993)
0.1 1.7 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.1 1.3 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.1 1.1 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.1 0.5 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.1 0.8 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 0.3 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 0.5 GO:0004925 prolactin receptor activity(GO:0004925)
0.1 1.2 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 0.3 GO:0003978 UDP-glucose 4-epimerase activity(GO:0003978) UTP:galactose-1-phosphate uridylyltransferase activity(GO:0017103)
0.1 0.2 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.1 0.2 GO:0031013 troponin I binding(GO:0031013)
0.1 0.3 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 2.5 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.3 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 1.1 GO:1990459 transferrin receptor binding(GO:1990459)
0.1 2.2 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 2.8 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 0.9 GO:0070097 delta-catenin binding(GO:0070097)
0.1 0.6 GO:0001849 complement component C1q binding(GO:0001849)
0.1 0.9 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.5 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.1 0.4 GO:0033142 progesterone receptor binding(GO:0033142)
0.1 0.5 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.1 0.2 GO:0031403 lithium ion binding(GO:0031403)
0.1 0.7 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.6 GO:0043237 laminin-1 binding(GO:0043237)
0.1 0.6 GO:0031419 cobalamin binding(GO:0031419)
0.1 2.4 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 0.2 GO:0046923 ER retention sequence binding(GO:0046923)
0.1 1.5 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 1.7 GO:0004697 protein kinase C activity(GO:0004697)
0.1 1.4 GO:0008171 O-methyltransferase activity(GO:0008171)
0.1 0.8 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 1.1 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 0.7 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 2.1 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 2.2 GO:0030552 cAMP binding(GO:0030552)
0.0 0.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.5 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0 0.6 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.9 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 0.6 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.1 GO:0035827 rubidium ion transmembrane transporter activity(GO:0035827)
0.0 1.9 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.3 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 6.7 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.1 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.3 GO:0016936 galactoside binding(GO:0016936)
0.0 2.0 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.3 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 1.8 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.3 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.0 0.7 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 1.0 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 1.1 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 1.0 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.3 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.3 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888) endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters(GO:0016893)
0.0 2.2 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 1.0 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.1 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.0 1.2 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 2.3 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.2 GO:0010857 calcium-dependent protein kinase activity(GO:0010857)
0.0 0.7 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.8 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.5 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596) H4 histone acetyltransferase activity(GO:0010485)
0.0 0.1 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.0 1.5 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.3 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.3 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 2.7 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 1.2 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.3 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 1.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 1.1 GO:0030676 NMDA glutamate receptor activity(GO:0004972) Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.9 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.1 GO:0038100 nodal binding(GO:0038100)
0.0 0.1 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.8 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.5 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.1 GO:1905394 retromer complex binding(GO:1905394)
0.0 0.2 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.3 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.3 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 1.0 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.6 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.2 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 1.0 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.5 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.1 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.0 0.3 GO:0031386 protein tag(GO:0031386)
0.0 0.1 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.5 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.4 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.3 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
0.0 0.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.5 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114) phosphate transmembrane transporter activity(GO:1901677)
0.0 0.3 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.3 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.3 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.3 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.5 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.4 GO:0030275 LRR domain binding(GO:0030275)
0.0 1.1 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.0 GO:0031686 A1 adenosine receptor binding(GO:0031686)
0.0 0.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.3 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.2 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396)
0.0 0.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0 0.4 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 2.5 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 0.1 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.4 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.0 1.0 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.5 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.9 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors(GO:0016667)
0.0 1.0 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.5 GO:0009055 electron carrier activity(GO:0009055)
0.0 2.8 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.2 GO:0046933 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.6 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.1 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.1 GO:0002046 opsin binding(GO:0002046)
0.0 0.8 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 2.5 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.2 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.3 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.2 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.0 0.2 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0 0.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 1.1 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.3 GO:0004690 cyclic nucleotide-dependent protein kinase activity(GO:0004690)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.1 2.2 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.1 5.8 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 2.8 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 1.2 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 2.1 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.0 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 2.1 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.0 0.9 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.0 3.2 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.7 PID_PI3K_PLC_TRK_PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.8 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.3 PID_ALK2_PATHWAY ALK2 signaling events
0.0 0.9 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.7 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 0.4 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.0 1.1 PID_EPHB_FWD_PATHWAY EPHB forward signaling
0.0 0.4 ST_G_ALPHA_I_PATHWAY G alpha i Pathway
0.0 0.8 PID_TRAIL_PATHWAY TRAIL signaling pathway
0.0 0.6 ST_P38_MAPK_PATHWAY p38 MAPK Pathway
0.0 0.7 PID_BMP_PATHWAY BMP receptor signaling
0.0 0.6 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.0 0.3 PID_A6B1_A6B4_INTEGRIN_PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.7 PID_VEGFR1_2_PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.8 PID_IL4_2PATHWAY IL4-mediated signaling events
0.0 0.5 PID_PTP1B_PATHWAY Signaling events mediated by PTP1B
0.0 0.8 PID_MTOR_4PATHWAY mTOR signaling pathway
0.0 0.4 PID_CD8_TCR_DOWNSTREAM_PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.1 PID_PS1_PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.1 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.0 0.6 PID_NOTCH_PATHWAY Notch signaling pathway
0.0 0.3 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.7 REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.2 2.2 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade
0.2 2.7 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism
0.1 4.1 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 3.0 REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.1 1.5 REACTOME_TRANSPORT_OF_ORGANIC_ANIONS Genes involved in Transport of organic anions
0.1 1.7 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 8.8 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.1 1.6 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.1 0.8 REACTOME_OPSINS Genes involved in Opsins
0.1 1.7 REACTOME_COMPLEMENT_CASCADE Genes involved in Complement cascade
0.1 8.2 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 3.0 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 1.2 REACTOME_SIGNALING_BY_NOTCH2 Genes involved in Signaling by NOTCH2
0.1 1.8 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.1 1.8 REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 0.6 REACTOME_AMYLOIDS Genes involved in Amyloids
0.1 0.9 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 0.2 REACTOME_DESTABILIZATION_OF_MRNA_BY_BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.1 1.0 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 1.5 REACTOME_LIGAND_GATED_ION_CHANNEL_TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 1.7 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.0 0.7 REACTOME_PROLACTIN_RECEPTOR_SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.6 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism
0.0 1.2 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 1.0 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.7 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 1.3 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.0 1.0 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.8 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.7 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 1.1 REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.7 REACTOME_REGULATION_OF_AMPK_ACTIVITY_VIA_LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.3 REACTOME_HORMONE_LIGAND_BINDING_RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.9 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.5 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.4 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.4 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.1 REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.5 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.0 0.4 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.0 0.5 REACTOME_ACTIVATION_OF_GENES_BY_ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.3 REACTOME_RESOLUTION_OF_AP_SITES_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0 1.1 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.3 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.2 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.5 REACTOME_UNBLOCKING_OF_NMDA_RECEPTOR_GLUTAMATE_BINDING_AND_ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 0.5 REACTOME_RIG_I_MDA5_MEDIATED_INDUCTION_OF_IFN_ALPHA_BETA_PATHWAYS Genes involved in RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
0.0 0.5 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.4 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 1.3 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.3 REACTOME_FGFR4_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.4 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 0.6 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.9 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.5 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.0 3.8 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 2.4 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.1 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.2 REACTOME_INTEGRIN_ALPHAIIB_BETA3_SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.0 0.3 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.4 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.1 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins