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GSE58827: Dynamics of the Mouse Liver

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Results for Nr4a3

Z-value: 0.64

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Transcription factors associated with Nr4a3

Gene Symbol Gene ID Gene Info
Nr4a3
ENSMUSG00000028341.3 nuclear receptor subfamily 4, group A, member 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nr4a3mm10_v2_chr4_+_48045144_480451600.153.8e-01Click!

Activity profile of Nr4a3 motif

Sorted Z-values of Nr4a3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr9_-_46235260 3.19 ENSMUST00000121916.1
ENSMUST00000034586.2
Apoc3
apolipoprotein C-III
chr10_-_127370535 2.26 ENSMUST00000026472.8
Inhbc
inhibin beta-C
chr9_-_22002599 2.20 ENSMUST00000115336.2
ENSMUST00000044926.5
Ccdc151
coiled-coil domain containing 151
chr2_+_68117713 1.95 ENSMUST00000112346.2
B3galt1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr9_-_46235631 1.93 ENSMUST00000118649.1
Apoc3
apolipoprotein C-III
chr11_-_72266596 1.49 ENSMUST00000021161.6
ENSMUST00000140167.1
Slc13a5
solute carrier family 13 (sodium-dependent citrate transporter), member 5
chr13_-_41847482 1.46 ENSMUST00000072012.3
Adtrp
androgen dependent TFPI regulating protein
chr13_-_41847599 1.39 ENSMUST00000179758.1
Adtrp
androgen dependent TFPI regulating protein
chr6_+_91157373 1.28 ENSMUST00000155007.1
Hdac11
histone deacetylase 11
chr9_-_70141484 1.27 ENSMUST00000034749.8
Fam81a
family with sequence similarity 81, member A
chr19_-_4498574 1.17 ENSMUST00000048482.6
2010003K11Rik
RIKEN cDNA 2010003K11 gene
chr11_-_53423123 1.16 ENSMUST00000036045.5
Leap2
liver-expressed antimicrobial peptide 2
chr7_+_140920940 1.13 ENSMUST00000184560.1
Nlrp6
NLR family, pyrin domain containing 6
chr7_+_140920896 1.11 ENSMUST00000183845.1
ENSMUST00000106045.1
Nlrp6
NLR family, pyrin domain containing 6
chr5_-_66151323 1.08 ENSMUST00000131838.1
Rbm47
RNA binding motif protein 47
chr17_-_73950172 1.07 ENSMUST00000024866.4
Xdh
xanthine dehydrogenase
chr11_+_75510077 1.06 ENSMUST00000042972.6
Rilp
Rab interacting lysosomal protein
chr4_+_134396320 1.04 ENSMUST00000105869.2
Pafah2
platelet-activating factor acetylhydrolase 2
chr8_+_13026024 1.03 ENSMUST00000033820.3
F7
coagulation factor VII
chr6_+_91156772 1.02 ENSMUST00000143621.1
Hdac11
histone deacetylase 11
chr4_-_141623799 0.98 ENSMUST00000038661.7
Slc25a34
solute carrier family 25, member 34
chr7_+_100009914 0.93 ENSMUST00000107084.1
Chrdl2
chordin-like 2
chr6_-_113531575 0.88 ENSMUST00000032425.5
Emc3
ER membrane protein complex subunit 3
chr19_+_44989073 0.88 ENSMUST00000026225.8
Sema4g
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr6_+_91156665 0.85 ENSMUST00000041736.4
Hdac11
histone deacetylase 11
chr7_-_79842287 0.83 ENSMUST00000049004.6
Anpep
alanyl (membrane) aminopeptidase
chr9_-_64341145 0.82 ENSMUST00000120760.1
ENSMUST00000168844.2
Dis3l
DIS3 mitotic control homolog (S. cerevisiae)-like
chr10_-_20724696 0.80 ENSMUST00000170265.1
Pde7b
phosphodiesterase 7B
chr11_-_100822525 0.79 ENSMUST00000107358.2
Stat5b
signal transducer and activator of transcription 5B
chr17_-_35909626 0.74 ENSMUST00000141132.1
Atat1
alpha tubulin acetyltransferase 1
chr16_+_10545390 0.74 ENSMUST00000115827.1
ENSMUST00000038145.6
ENSMUST00000150894.1
Clec16a
C-type lectin domain family 16, member A
chrX_+_73675500 0.72 ENSMUST00000171398.1
Slc6a8
solute carrier family 6 (neurotransmitter transporter, creatine), member 8
chr4_-_129227883 0.71 ENSMUST00000106051.1
C77080
expressed sequence C77080
chr4_+_134397380 0.68 ENSMUST00000105870.1
Pafah2
platelet-activating factor acetylhydrolase 2
chr16_-_20730544 0.66 ENSMUST00000076422.5
Thpo
thrombopoietin
chr15_+_54952939 0.66 ENSMUST00000181704.1
Gm26684
predicted gene, 26684
chr2_-_180273488 0.64 ENSMUST00000108891.1
Cables2
CDK5 and Abl enzyme substrate 2
chr2_+_157279026 0.63 ENSMUST00000116380.2
Rpn2
ribophorin II
chr10_+_59403644 0.63 ENSMUST00000009790.7
Pla2g12b
phospholipase A2, group XIIB
chr15_-_76200577 0.62 ENSMUST00000169108.1
ENSMUST00000170728.1
Plec
plectin
chr3_-_138131356 0.62 ENSMUST00000029805.8
Mttp
microsomal triglyceride transfer protein
chr9_-_22085391 0.58 ENSMUST00000179422.1
ENSMUST00000098937.3
ENSMUST00000177967.1
ENSMUST00000180180.1
Ecsit
ECSIT homolog (Drosophila)
chr11_-_55033398 0.58 ENSMUST00000108883.3
ENSMUST00000102727.2
Anxa6
annexin A6
chr16_+_10545339 0.57 ENSMUST00000066345.7
ENSMUST00000115824.3
ENSMUST00000155633.1
Clec16a
C-type lectin domain family 16, member A
chr11_+_116657106 0.56 ENSMUST00000116318.2
Gm11744
predicted gene 11744
chr2_+_157279065 0.56 ENSMUST00000029171.5
Rpn2
ribophorin II
chr9_-_70934808 0.51 ENSMUST00000034731.8
Lipc
lipase, hepatic
chr8_+_108714644 0.50 ENSMUST00000043896.8
Zfhx3
zinc finger homeobox 3
chr4_-_152128858 0.49 ENSMUST00000049305.7
Espn
espin
chr6_+_41546730 0.48 ENSMUST00000103299.1
Trbc2
T cell receptor beta, constant 2
chr15_+_76343504 0.46 ENSMUST00000023210.6
Cyc1
cytochrome c-1
chrX_+_150589907 0.45 ENSMUST00000080884.4
Pfkfb1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr7_-_127345314 0.44 ENSMUST00000060783.5
Zfp768
zinc finger protein 768
chr19_+_46152505 0.42 ENSMUST00000026254.7
Gbf1
golgi-specific brefeldin A-resistance factor 1
chr8_+_120668222 0.41 ENSMUST00000034276.6
ENSMUST00000181586.1
Cox4i1
cytochrome c oxidase subunit IV isoform 1
chr7_+_45896941 0.40 ENSMUST00000069772.7
ENSMUST00000107716.1
Tmem143
transmembrane protein 143
chr2_+_79707780 0.39 ENSMUST00000090760.2
ENSMUST00000040863.4
ENSMUST00000111780.2
Ppp1r1c
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr11_+_74649462 0.38 ENSMUST00000092915.5
ENSMUST00000117818.1
Cluh
clustered mitochondria (cluA/CLU1) homolog
chr13_+_41655697 0.38 ENSMUST00000067176.8
Gm5082
predicted gene 5082
chr8_+_120668308 0.38 ENSMUST00000181795.1
Cox4i1
cytochrome c oxidase subunit IV isoform 1
chrX_-_71492799 0.36 ENSMUST00000037391.5
ENSMUST00000114586.2
ENSMUST00000114587.2
Cd99l2
CD99 antigen-like 2
chr17_-_35910032 0.36 ENSMUST00000141662.1
ENSMUST00000056034.6
ENSMUST00000077494.6
ENSMUST00000149277.1
ENSMUST00000061052.5
Atat1
alpha tubulin acetyltransferase 1
chr3_-_101287897 0.35 ENSMUST00000029456.4
Cd2
CD2 antigen
chr15_-_79804717 0.34 ENSMUST00000023057.8
Nptxr
neuronal pentraxin receptor
chr7_+_102267795 0.34 ENSMUST00000033289.4
Stim1
stromal interaction molecule 1
chr10_-_20725023 0.34 ENSMUST00000020165.7
Pde7b
phosphodiesterase 7B
chr9_-_110989611 0.34 ENSMUST00000084922.5
Rtp3
receptor transporter protein 3
chr7_-_126475082 0.33 ENSMUST00000032978.6
Sh2b1
SH2B adaptor protein 1
chr1_+_75435930 0.33 ENSMUST00000037796.7
ENSMUST00000113584.1
ENSMUST00000145166.1
ENSMUST00000143730.1
ENSMUST00000133418.1
ENSMUST00000144874.1
ENSMUST00000140287.1
Gmppa
GDP-mannose pyrophosphorylase A
chr7_+_30712209 0.33 ENSMUST00000005692.6
ENSMUST00000170371.1
Atp4a
ATPase, H+/K+ exchanging, gastric, alpha polypeptide
chr4_+_99955715 0.32 ENSMUST00000102783.4
Pgm2
phosphoglucomutase 2
chr11_+_83850832 0.31 ENSMUST00000021016.3
Hnf1b
HNF1 homeobox B
chr4_-_41697040 0.31 ENSMUST00000102962.3
ENSMUST00000084701.5
Cntfr
ciliary neurotrophic factor receptor
chr18_-_60624201 0.31 ENSMUST00000155195.2
Synpo
synaptopodin
chr7_-_79466167 0.30 ENSMUST00000073889.7
Polg
polymerase (DNA directed), gamma
chr4_-_150914401 0.30 ENSMUST00000105675.1
Park7
Parkinson disease (autosomal recessive, early onset) 7
chr3_-_101287879 0.30 ENSMUST00000152321.1
Cd2
CD2 antigen
chr8_-_120668058 0.28 ENSMUST00000181333.1
ENSMUST00000181950.1
Gm27021
Emc8
predicted gene, 27021
ER membrane protein complex subunit 8
chr12_-_111966954 0.28 ENSMUST00000021719.5
2010107E04Rik
RIKEN cDNA 2010107E04 gene
chr11_+_90638127 0.27 ENSMUST00000020851.8
Cox11
cytochrome c oxidase assembly protein 11
chr11_+_83850863 0.25 ENSMUST00000108114.2
Hnf1b
HNF1 homeobox B
chr18_-_60624304 0.25 ENSMUST00000097566.3
Synpo
synaptopodin
chr14_+_64589802 0.24 ENSMUST00000180610.1
A930011O12Rik
RIKEN cDNA A930011O12 gene
chr2_+_92375306 0.24 ENSMUST00000028650.8
Pex16
peroxisomal biogenesis factor 16
chr7_+_45897429 0.23 ENSMUST00000140243.1
Tmem143
transmembrane protein 143
chr9_+_22003035 0.22 ENSMUST00000115331.2
ENSMUST00000003493.7
Prkcsh
protein kinase C substrate 80K-H
chr3_-_89213840 0.21 ENSMUST00000173477.1
ENSMUST00000119222.1
Mtx1
metaxin 1
chr8_-_22060019 0.21 ENSMUST00000110738.2
Atp7b
ATPase, Cu++ transporting, beta polypeptide
chr8_-_120668121 0.20 ENSMUST00000034277.7
Emc8
ER membrane protein complex subunit 8
chr9_-_80465429 0.20 ENSMUST00000085289.5
ENSMUST00000185068.1
ENSMUST00000113250.3
Impg1
interphotoreceptor matrix proteoglycan 1
chr1_+_36691487 0.19 ENSMUST00000081180.4
Cox5b
cytochrome c oxidase subunit Vb
chr19_-_4334001 0.19 ENSMUST00000176653.1
Kdm2a
lysine (K)-specific demethylase 2A
chr6_-_138426735 0.17 ENSMUST00000162932.1
Lmo3
LIM domain only 3
chr7_-_109616548 0.17 ENSMUST00000077909.1
ENSMUST00000084738.3
St5
suppression of tumorigenicity 5
chr2_-_76868375 0.17 ENSMUST00000149616.1
ENSMUST00000152185.1
ENSMUST00000130915.1
ENSMUST00000155365.1
ENSMUST00000128071.1
Ttn
titin
chr8_+_119862239 0.17 ENSMUST00000034287.8
Klhl36
kelch-like 36
chr11_-_99244058 0.17 ENSMUST00000103132.3
ENSMUST00000038214.6
Krt222
keratin 222
chr12_-_111672290 0.16 ENSMUST00000001304.7
Ckb
creatine kinase, brain
chr15_-_79141197 0.14 ENSMUST00000169604.1
1700088E04Rik
RIKEN cDNA 1700088E04 gene
chr2_+_69670100 0.13 ENSMUST00000100050.3
Klhl41
kelch-like 41
chr2_-_33468493 0.11 ENSMUST00000113156.1
ENSMUST00000028125.5
ENSMUST00000126442.1
Zbtb43
zinc finger and BTB domain containing 43
chr6_-_28421680 0.10 ENSMUST00000090511.3
Gcc1
golgi coiled coil 1
chr4_-_116075022 0.10 ENSMUST00000050580.4
ENSMUST00000078676.5
Uqcrh
ubiquinol-cytochrome c reductase hinge protein
chr11_+_70764209 0.10 ENSMUST00000060444.5
Zfp3
zinc finger protein 3
chr2_+_178141920 0.07 ENSMUST00000103066.3
Phactr3
phosphatase and actin regulator 3
chr15_+_79141324 0.07 ENSMUST00000040077.6
Polr2f
polymerase (RNA) II (DNA directed) polypeptide F
chr2_+_59160838 0.07 ENSMUST00000102754.4
ENSMUST00000168631.1
ENSMUST00000123908.1
Pkp4
plakophilin 4
chr4_+_150914562 0.06 ENSMUST00000135169.1
Tnfrsf9
tumor necrosis factor receptor superfamily, member 9
chr13_-_73328442 0.05 ENSMUST00000022097.5
Ndufs6
NADH dehydrogenase (ubiquinone) Fe-S protein 6
chr3_-_89773221 0.03 ENSMUST00000038450.1
4632404H12Rik
RIKEN cDNA 4632404H12 gene
chr2_-_165283599 0.03 ENSMUST00000155289.1
Slc35c2
solute carrier family 35, member C2
chr16_-_18248697 0.03 ENSMUST00000115645.3
Ranbp1
RAN binding protein 1
chr5_-_66151903 0.02 ENSMUST00000167950.1
Rbm47
RNA binding motif protein 47
chrX_+_101299207 0.02 ENSMUST00000065858.2
Nlgn3
neuroligin 3
chr2_-_157279519 0.02 ENSMUST00000143663.1
Mroh8
maestro heat-like repeat family member 8

Network of associatons between targets according to the STRING database.

First level regulatory network of Nr4a3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 5.1 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
0.4 1.5 GO:0015744 succinate transport(GO:0015744)
0.4 1.1 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.4 1.1 GO:0070676 intralumenal vesicle formation(GO:0070676)
0.3 1.3 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.3 1.0 GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641)
0.2 0.7 GO:0015881 creatine transport(GO:0015881)
0.2 2.0 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.2 1.1 GO:0009115 xanthine catabolic process(GO:0009115)
0.2 0.5 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.2 0.7 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.2 2.2 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.1 0.6 GO:1901146 regulation of pronephros size(GO:0035565) mesonephros morphogenesis(GO:0061206) mesonephric nephron development(GO:0061215) mesonephric nephron morphogenesis(GO:0061228) mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis(GO:0061235) regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061295) negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061296) mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:1901146)
0.1 0.4 GO:0035964 COPI-coated vesicle budding(GO:0035964) protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 2.2 GO:0036158 outer dynein arm assembly(GO:0036158)
0.1 0.8 GO:0070672 positive regulation of natural killer cell proliferation(GO:0032819) response to interleukin-15(GO:0070672)
0.1 0.6 GO:0098886 modification of dendritic spine(GO:0098886)
0.1 1.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 0.9 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 0.7 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 0.3 GO:1903189 enzyme active site formation via L-cysteine sulfinic acid(GO:0018323) primary alcohol biosynthetic process(GO:0034309) cellular response to glyoxal(GO:0036471) glycolate biosynthetic process(GO:0046295) negative regulation of TRAIL-activated apoptotic signaling pathway(GO:1903122) regulation of pyrroline-5-carboxylate reductase activity(GO:1903167) positive regulation of pyrroline-5-carboxylate reductase activity(GO:1903168) regulation of tyrosine 3-monooxygenase activity(GO:1903176) positive regulation of tyrosine 3-monooxygenase activity(GO:1903178) L-dopa metabolic process(GO:1903184) L-dopa biosynthetic process(GO:1903185) glyoxal metabolic process(GO:1903189) regulation of L-dopa biosynthetic process(GO:1903195) positive regulation of L-dopa biosynthetic process(GO:1903197) regulation of L-dopa decarboxylase activity(GO:1903198) positive regulation of L-dopa decarboxylase activity(GO:1903200) positive regulation of cellular amino acid biosynthetic process(GO:2000284)
0.1 0.6 GO:0034197 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.1 0.3 GO:0003360 brainstem development(GO:0003360)
0.1 0.8 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.1 0.5 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
0.1 0.3 GO:0032237 activation of store-operated calcium channel activity(GO:0032237)
0.1 0.2 GO:0015680 intracellular copper ion transport(GO:0015680)
0.1 3.0 GO:0014003 oligodendrocyte development(GO:0014003)
0.1 0.8 GO:0035814 negative regulation of renal sodium excretion(GO:0035814)
0.1 0.5 GO:0071830 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830)
0.1 0.5 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.6 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.7 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715) positive regulation of interleukin-8 secretion(GO:2000484)
0.0 0.2 GO:0043056 forward locomotion(GO:0043056)
0.0 0.2 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.0 0.3 GO:0019388 galactose catabolic process(GO:0019388)
0.0 2.3 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.3 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.2 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.0 0.6 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.0 0.6 GO:0055090 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.0 0.3 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.0 0.4 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.2 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.0 0.9 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.3 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.3 GO:0010155 regulation of proton transport(GO:0010155)
0.0 0.9 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.1 GO:2001183 negative regulation of interleukin-12 secretion(GO:2001183)
0.0 0.5 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 1.4 GO:0006487 protein N-linked glycosylation(GO:0006487)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 5.1 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.3 1.3 GO:0036019 endolysosome(GO:0036019)
0.2 0.5 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.1 1.1 GO:0097427 microtubule bundle(GO:0097427)
0.1 2.2 GO:0061702 inflammasome complex(GO:0061702)
0.1 1.4 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 0.8 GO:0031983 vesicle lumen(GO:0031983)
0.1 1.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 0.6 GO:0097444 spine apparatus(GO:0097444)
0.1 0.8 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.1 0.2 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.1 0.5 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.0 0.3 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.6 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.5 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.5 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 2.7 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.6 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.5 GO:0032426 stereocilium tip(GO:0032426)
0.0 3.3 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.5 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.3 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 0.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.7 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.6 GO:0031902 late endosome membrane(GO:0031902)
0.0 1.0 GO:0016529 sarcoplasmic reticulum(GO:0016529)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 5.1 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.5 1.5 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.5 2.0 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.2 2.2 GO:0005000 vasopressin receptor activity(GO:0005000)
0.2 0.7 GO:0005308 creatine transmembrane transporter activity(GO:0005308)
0.2 1.1 GO:0016726 xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726)
0.2 1.7 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.2 1.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1 3.2 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 0.3 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.1 0.3 GO:0036478 tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478)
0.1 1.2 GO:0004579 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 0.3 GO:0001847 opsonin receptor activity(GO:0001847)
0.1 0.5 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.1 0.3 GO:0031849 olfactory receptor binding(GO:0031849)
0.1 0.5 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.1 0.2 GO:0043682 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
0.0 0.4 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.3 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.3 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.0 0.8 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 2.3 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 1.1 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.2 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.2 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 0.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.8 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.8 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 1.1 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.6 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.6 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.5 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.2 GO:0031433 telethonin binding(GO:0031433)
0.0 0.4 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.6 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.1 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.7 GO:0009055 electron carrier activity(GO:0009055)
0.0 0.3 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 3.2 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.8 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.4 PID ARF 3PATHWAY Arf1 pathway
0.0 1.3 PID CMYB PATHWAY C-MYB transcription factor network
0.0 3.7 NABA SECRETED FACTORS Genes encoding secreted soluble factors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.3 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.2 6.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 1.5 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 1.1 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 1.0 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 1.1 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 3.0 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.3 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.4 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 1.6 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.6 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.3 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 1.2 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.0 0.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.7 REACTOME PLATELET AGGREGATION PLUG FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.0 0.6 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.5 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases