Motif ID: Pitx2_Otx2

Z-value: 2.179

Transcription factors associated with Pitx2_Otx2:

Gene SymbolEntrez IDGene Name
Otx2 ENSMUSG00000021848.9 Otx2
Pitx2 ENSMUSG00000028023.10 Pitx2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pitx2mm10_v2_chr3_+_129199919_1291999430.626.1e-05Click!
Otx2mm10_v2_chr14_-_48662740_486628720.241.5e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Pitx2_Otx2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_+_36184082 30.103 ENSMUST00000114858.1
Gm5483
predicted gene 5483
chr16_-_36367623 27.572 ENSMUST00000096089.2
BC100530
cDNA sequence BC100530
chr14_-_70630149 17.930 ENSMUST00000022694.9
Dmtn
dematin actin binding protein
chrX_-_7978027 16.806 ENSMUST00000125418.1
Gata1
GATA binding protein 1
chr5_+_90490714 15.581 ENSMUST00000042755.3
Afp
alpha fetoprotein
chr2_-_126500631 15.041 ENSMUST00000129187.1
Atp8b4
ATPase, class I, type 8B, member 4
chr16_+_36277145 14.877 ENSMUST00000042097.9
Stfa1
stefin A1
chrX_-_7967817 14.502 ENSMUST00000033502.7
Gata1
GATA binding protein 1
chr10_+_79886302 14.137 ENSMUST00000046091.5
Elane
elastase, neutrophil expressed
chr6_-_88898664 13.920 ENSMUST00000058011.6
Mcm2
minichromosome maintenance deficient 2 mitotin (S. cerevisiae)
chr15_-_76669811 13.786 ENSMUST00000037824.4
Foxh1
forkhead box H1
chr16_-_36334330 11.615 ENSMUST00000114850.2
BC117090
cDNA sequence BC1179090
chr11_-_83286722 11.438 ENSMUST00000163961.2
Slfn14
schlafen family member 14
chr17_-_35085609 10.995 ENSMUST00000038507.6
Ly6g6f
lymphocyte antigen 6 complex, locus G6F
chr9_-_70421533 10.880 ENSMUST00000034742.6
Ccnb2
cyclin B2
chr6_-_115762346 10.804 ENSMUST00000166254.1
ENSMUST00000170625.1
Tmem40

transmembrane protein 40

chr16_+_32186192 10.402 ENSMUST00000099990.3
Bex6
brain expressed gene 6
chr17_+_48232755 10.088 ENSMUST00000113251.3
ENSMUST00000048782.6
Trem1

triggering receptor expressed on myeloid cells 1

chr19_-_45812291 10.045 ENSMUST00000086993.4
Kcnip2
Kv channel-interacting protein 2
chr11_-_55185029 9.956 ENSMUST00000039305.5
Slc36a2
solute carrier family 36 (proton/amino acid symporter), member 2
chr17_+_29114142 9.868 ENSMUST00000141797.1
ENSMUST00000132262.1
ENSMUST00000141239.1
ENSMUST00000138816.1
Gm16194



predicted gene 16194



chr15_-_78855517 9.805 ENSMUST00000044584.4
Lgals2
lectin, galactose-binding, soluble 2
chr7_+_16781341 9.629 ENSMUST00000108496.2
Slc1a5
solute carrier family 1 (neutral amino acid transporter), member 5
chrX_+_164140447 9.374 ENSMUST00000073973.4
Ace2
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
chr17_-_35188427 9.297 ENSMUST00000097336.4
Lst1
leukocyte specific transcript 1
chr11_+_61956779 9.275 ENSMUST00000049836.7
Specc1
sperm antigen with calponin homology and coiled-coil domains 1
chr11_+_117782281 9.267 ENSMUST00000050874.7
ENSMUST00000106334.2
Tmc8

transmembrane channel-like gene family 8

chr3_-_90695706 9.218 ENSMUST00000069960.5
ENSMUST00000117167.1
S100a9

S100 calcium binding protein A9 (calgranulin B)

chr11_+_117782076 9.133 ENSMUST00000127080.1
Tmc8
transmembrane channel-like gene family 8
chr11_-_6520894 9.100 ENSMUST00000003459.3
Myo1g
myosin IG
chr11_-_97996171 8.986 ENSMUST00000042971.9
Arl5c
ADP-ribosylation factor-like 5C
chr7_-_75782080 8.935 ENSMUST00000181224.1
AU020206
expressed sequence AU020206
chr10_-_62342674 8.856 ENSMUST00000143179.1
ENSMUST00000130422.1
Hk1

hexokinase 1

chr7_-_47528862 8.826 ENSMUST00000172559.1
Mrgpra2b
MAS-related GPR, member A2B
chr7_+_141131268 8.598 ENSMUST00000026568.8
Ptdss2
phosphatidylserine synthase 2
chr17_-_25944932 8.518 ENSMUST00000085027.3
Nhlrc4
NHL repeat containing 4
chr4_-_117182623 8.366 ENSMUST00000065896.2
Kif2c
kinesin family member 2C
chr18_-_60501983 8.286 ENSMUST00000042710.6
Smim3
small integral membrane protein 3
chr17_+_35861318 8.222 ENSMUST00000074259.8
ENSMUST00000174873.1
Nrm

nurim (nuclear envelope membrane protein)

chr14_-_47411666 8.163 ENSMUST00000111778.3
Dlgap5
discs, large (Drosophila) homolog-associated protein 5
chr16_+_36210403 8.100 ENSMUST00000089628.3
Gm5416
predicted gene 5416
chr13_-_22009730 8.049 ENSMUST00000006341.2
Prss16
protease, serine, 16 (thymus)
chr13_+_54701457 7.974 ENSMUST00000037145.7
Cdhr2
cadherin-related family member 2
chr9_+_110419750 7.856 ENSMUST00000035061.6
Ngp
neutrophilic granule protein
chr14_+_32166104 7.825 ENSMUST00000164341.1
Ncoa4
nuclear receptor coactivator 4
chr3_-_36571952 7.562 ENSMUST00000029270.3
Ccna2
cyclin A2
chr8_-_10928449 7.480 ENSMUST00000040608.3
3930402G23Rik
RIKEN cDNA 3930402G23 gene
chr8_+_23139064 7.446 ENSMUST00000033947.8
Ank1
ankyrin 1, erythroid
chr7_-_6696423 7.399 ENSMUST00000002336.8
Zim1
zinc finger, imprinted 1
chr6_+_86628174 7.243 ENSMUST00000043400.6
Asprv1
aspartic peptidase, retroviral-like 1
chr8_+_84901928 7.236 ENSMUST00000067060.7
Klf1
Kruppel-like factor 1 (erythroid)
chr7_+_35449035 7.184 ENSMUST00000118969.1
ENSMUST00000118383.1
Slc7a9

solute carrier family 7 (cationic amino acid transporter, y+ system), member 9

chr11_+_95010277 7.139 ENSMUST00000124735.1
Samd14
sterile alpha motif domain containing 14
chr8_+_23139030 7.081 ENSMUST00000121075.1
Ank1
ankyrin 1, erythroid
chr11_-_117782182 7.051 ENSMUST00000152304.1
Tmc6
transmembrane channel-like gene family 6
chr14_-_47418407 6.752 ENSMUST00000043296.3
Dlgap5
discs, large (Drosophila) homolog-associated protein 5
chr5_+_76656512 6.750 ENSMUST00000086909.4
Gm10430
predicted gene 10430
chr9_+_107992463 6.718 ENSMUST00000177173.1
Cdhr4
cadherin-related family member 4
chr10_+_20347788 6.662 ENSMUST00000169712.1
Mtfr2
mitochondrial fission regulator 2
chr17_+_35861343 6.655 ENSMUST00000172931.1
Nrm
nurim (nuclear envelope membrane protein)
chr16_+_38362205 6.652 ENSMUST00000023494.6
Popdc2
popeye domain containing 2
chr8_-_85386310 6.633 ENSMUST00000137290.1
Mylk3
myosin light chain kinase 3
chr1_+_134111233 6.596 ENSMUST00000159963.1
ENSMUST00000160060.1
Chit1

chitinase 1 (chitotriosidase)

chr3_-_105932664 6.581 ENSMUST00000098758.2
I830077J02Rik
RIKEN cDNA I830077J02 gene
chr11_-_116581446 6.569 ENSMUST00000082152.4
Ube2o
ubiquitin-conjugating enzyme E2O
chr10_+_75948292 6.495 ENSMUST00000000926.2
Vpreb3
pre-B lymphocyte gene 3
chr12_+_79208928 6.466 ENSMUST00000122227.1
Rdh12
retinol dehydrogenase 12
chr12_+_79208904 6.400 ENSMUST00000021548.5
Rdh12
retinol dehydrogenase 12
chr10_-_128401218 6.372 ENSMUST00000042666.5
Slc39a5
solute carrier family 39 (metal ion transporter), member 5
chrX_+_8271642 6.366 ENSMUST00000115590.1
Slc38a5
solute carrier family 38, member 5
chr7_-_45526146 6.330 ENSMUST00000167273.1
ENSMUST00000042105.8
Ppp1r15a

protein phosphatase 1, regulatory (inhibitor) subunit 15A

chr12_+_109734969 6.310 ENSMUST00000182268.1
ENSMUST00000181543.2
ENSMUST00000183116.1
Mirg


miRNA containing gene


chr7_-_143460989 6.299 ENSMUST00000167912.1
ENSMUST00000037287.6
Cdkn1c

cyclin-dependent kinase inhibitor 1C (P57)

chr16_+_32756336 6.297 ENSMUST00000135753.1
Muc4
mucin 4
chr14_+_27000362 6.223 ENSMUST00000035433.8
Hesx1
homeobox gene expressed in ES cells
chr6_+_134929089 6.159 ENSMUST00000183867.1
ENSMUST00000184991.1
ENSMUST00000183905.1
RP23-45G16.5


RP23-45G16.5


chr17_+_6430112 6.050 ENSMUST00000179569.1
Dynlt1b
dynein light chain Tctex-type 1B
chr6_+_134929118 6.026 ENSMUST00000185152.1
ENSMUST00000184504.1
RP23-45G16.5

RP23-45G16.5

chr16_+_38362234 6.014 ENSMUST00000114739.1
Popdc2
popeye domain containing 2
chr18_-_74207771 5.986 ENSMUST00000040188.8
ENSMUST00000177604.1
Ska1

spindle and kinetochore associated complex subunit 1

chr9_-_123678873 5.936 ENSMUST00000040960.6
Slc6a20a
solute carrier family 6 (neurotransmitter transporter), member 20A
chr7_+_45554893 5.838 ENSMUST00000107752.3
Hsd17b14
hydroxysteroid (17-beta) dehydrogenase 14
chr7_+_35449154 5.837 ENSMUST00000032703.9
Slc7a9
solute carrier family 7 (cationic amino acid transporter, y+ system), member 9
chr18_+_64254359 5.745 ENSMUST00000025477.7
St8sia3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr9_-_67832325 5.687 ENSMUST00000054500.5
C2cd4a
C2 calcium-dependent domain containing 4A
chr9_+_21029373 5.613 ENSMUST00000001040.5
Icam4
intercellular adhesion molecule 4, Landsteiner-Wiener blood group
chr7_-_30823766 5.541 ENSMUST00000053156.3
Ffar2
free fatty acid receptor 2
chr15_+_76879232 5.531 ENSMUST00000023179.5
Zfp7
zinc finger protein 7
chr6_-_136401830 5.519 ENSMUST00000058713.7
E330021D16Rik
RIKEN cDNA E330021D16 gene
chr3_-_54915867 5.515 ENSMUST00000070342.3
Sertm1
serine rich and transmembrane domain containing 1
chr11_-_5152218 5.490 ENSMUST00000163299.1
ENSMUST00000062821.6
Emid1

EMI domain containing 1

chr7_-_118116128 5.469 ENSMUST00000128482.1
ENSMUST00000131840.1
Rps15a

ribosomal protein S15A

chr7_+_28441026 5.461 ENSMUST00000135686.1
Gmfg
glia maturation factor, gamma
chr15_-_76639840 5.438 ENSMUST00000166974.1
ENSMUST00000168185.1
Tonsl

tonsoku-like, DNA repair protein

chr15_+_99006056 5.411 ENSMUST00000079818.3
Gm8973
predicted gene 8973
chr7_-_100514800 5.403 ENSMUST00000054923.7
Dnajb13
DnaJ (Hsp40) related, subfamily B, member 13
chr3_+_105870898 5.378 ENSMUST00000010279.5
Adora3
adenosine A3 receptor
chr4_-_149137536 5.368 ENSMUST00000176124.1
ENSMUST00000177408.1
ENSMUST00000105695.1
ENSMUST00000030813.3
Apitd1



apoptosis-inducing, TAF9-like domain 1



chr4_+_108579445 5.333 ENSMUST00000102744.3
Orc1
origin recognition complex, subunit 1
chr9_-_123678782 5.330 ENSMUST00000170591.1
ENSMUST00000171647.1
Slc6a20a

solute carrier family 6 (neurotransmitter transporter), member 20A

chr13_+_45507438 5.291 ENSMUST00000000260.6
Gmpr
guanosine monophosphate reductase
chr17_-_33713372 5.232 ENSMUST00000173392.1
March2
membrane-associated ring finger (C3HC4) 2
chr19_-_5986143 5.216 ENSMUST00000041827.7
Slc22a20
solute carrier family 22 (organic anion transporter), member 20
chr2_+_164940742 5.216 ENSMUST00000137626.1
Mmp9
matrix metallopeptidase 9
chr13_-_66851513 5.125 ENSMUST00000169322.1
Gm17404
predicted gene, 17404
chr9_-_107985863 5.118 ENSMUST00000048568.4
Fam212a
family with sequence similarity 212, member A
chr7_+_43427622 5.042 ENSMUST00000177164.2
Lim2
lens intrinsic membrane protein 2
chr1_+_86303221 5.034 ENSMUST00000113306.2
B3gnt7
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7
chr11_+_72961163 5.018 ENSMUST00000108486.1
ENSMUST00000108484.1
ENSMUST00000021142.7
ENSMUST00000108485.2
ENSMUST00000163326.1
Atp2a3




ATPase, Ca++ transporting, ubiquitous




chr9_-_44344159 4.977 ENSMUST00000077353.7
Hmbs
hydroxymethylbilane synthase
chrX_+_136666375 4.967 ENSMUST00000060904.4
ENSMUST00000113100.1
ENSMUST00000128040.1
Tceal3


transcription elongation factor A (SII)-like 3


chr15_+_101293196 4.900 ENSMUST00000071328.6
6030408B16Rik
RIKEN cDNA 6030408B16 gene
chr7_+_43440782 4.890 ENSMUST00000040227.1
Cldnd2
claudin domain containing 2
chr7_+_46861203 4.802 ENSMUST00000014545.4
Ldhc
lactate dehydrogenase C
chrX_-_162964557 4.769 ENSMUST00000038769.2
S100g
S100 calcium binding protein G
chr13_-_113100971 4.733 ENSMUST00000023897.5
Gzma
granzyme A
chr2_-_34913976 4.708 ENSMUST00000028232.3
Phf19
PHD finger protein 19
chr11_-_106998483 4.658 ENSMUST00000124541.1
Kpna2
karyopherin (importin) alpha 2
chr10_+_128908907 4.629 ENSMUST00000105229.1
Cd63
CD63 antigen
chr4_-_43483696 4.622 ENSMUST00000030180.6
Sit1
suppression inducing transmembrane adaptor 1
chr17_-_25727364 4.599 ENSMUST00000170070.1
ENSMUST00000048054.7
Chtf18

CTF18, chromosome transmission fidelity factor 18

chr9_+_111004811 4.593 ENSMUST00000080872.4
Gm10030
predicted gene 10030
chr11_+_101078411 4.591 ENSMUST00000019445.5
Hsd17b1
hydroxysteroid (17-beta) dehydrogenase 1
chr7_+_19291070 4.503 ENSMUST00000108468.3
Rtn2
reticulon 2 (Z-band associated protein)
chrX_-_9469288 4.498 ENSMUST00000015484.3
Cybb
cytochrome b-245, beta polypeptide
chrX_-_136203637 4.452 ENSMUST00000151592.1
ENSMUST00000131510.1
ENSMUST00000066819.4
Tceal5


transcription elongation factor A (SII)-like 5


chr11_+_4236411 4.416 ENSMUST00000075221.2
Osm
oncostatin M
chr10_+_128238034 4.405 ENSMUST00000105245.2
Timeless
timeless circadian clock 1
chr7_-_141655319 4.373 ENSMUST00000062451.7
Muc6
mucin 6, gastric
chr11_-_102925086 4.356 ENSMUST00000021311.9
Kif18b
kinesin family member 18B
chr10_-_79788924 4.352 ENSMUST00000020573.6
Prss57
protease, serine 57
chr7_-_133702515 4.319 ENSMUST00000153698.1
Uros
uroporphyrinogen III synthase
chr1_+_135232045 4.315 ENSMUST00000110798.3
Gm4204
predicted gene 4204
chr3_+_105870858 4.297 ENSMUST00000164730.1
Adora3
adenosine A3 receptor
chr8_+_71406003 4.262 ENSMUST00000119976.1
ENSMUST00000120725.1
Ankle1

ankyrin repeat and LEM domain containing 1

chr1_-_93342734 4.244 ENSMUST00000027493.3
Pask
PAS domain containing serine/threonine kinase
chr6_+_40964760 4.222 ENSMUST00000076638.5
1810009J06Rik
RIKEN cDNA 1810009J06 gene
chr7_-_110982443 4.147 ENSMUST00000005751.6
Mrvi1
MRV integration site 1
chr18_+_34751803 4.139 ENSMUST00000181453.1
ENSMUST00000181641.1
2010110K18Rik

RIKEN cDNA 2010110K18 gene

chr17_-_28942255 4.113 ENSMUST00000051526.4
Pxt1
peroxisomal, testis specific 1
chr13_+_120263114 4.094 ENSMUST00000181748.1
ENSMUST00000179905.1
AF067061

cDNA sequence AF067061

chr11_-_102897146 4.084 ENSMUST00000077902.4
Gfap
glial fibrillary acidic protein
chr11_+_44617310 4.078 ENSMUST00000081265.5
ENSMUST00000101326.3
ENSMUST00000109268.1
Ebf1


early B cell factor 1


chr19_-_42086338 4.064 ENSMUST00000051772.8
Morn4
MORN repeat containing 4
chr4_+_154011731 4.045 ENSMUST00000169622.1
ENSMUST00000030894.8
Lrrc47

leucine rich repeat containing 47

chr2_+_101624734 4.008 ENSMUST00000111227.1
Rag2
recombination activating gene 2
chr6_+_72544391 3.999 ENSMUST00000071044.6
ENSMUST00000114072.1
Capg

capping protein (actin filament), gelsolin-like

chr9_-_108190352 3.976 ENSMUST00000035208.7
Bsn
bassoon
chr16_+_17276291 3.942 ENSMUST00000164950.1
ENSMUST00000159242.1
Tmem191c

transmembrane protein 191C

chr6_-_122801639 3.936 ENSMUST00000165884.1
Slc2a3
solute carrier family 2 (facilitated glucose transporter), member 3
chr16_+_17208135 3.912 ENSMUST00000169803.1
Rimbp3
RIMS binding protein 3
chr7_-_19676749 3.785 ENSMUST00000003074.9
Apoc2
apolipoprotein C-II
chr7_-_128418154 3.773 ENSMUST00000033133.5
Rgs10
regulator of G-protein signalling 10
chr10_-_60696471 3.761 ENSMUST00000105461.3
ENSMUST00000105464.2
ENSMUST00000105463.2
Cdh23


cadherin 23 (otocadherin)


chr7_+_28440927 3.756 ENSMUST00000078845.6
Gmfg
glia maturation factor, gamma
chr16_-_57071346 3.754 ENSMUST00000067173.6
2310005G13Rik
RIKEN cDNA 2310005G13 gene
chrX_-_164250368 3.699 ENSMUST00000112263.1
Bmx
BMX non-receptor tyrosine kinase
chr5_-_100572192 3.693 ENSMUST00000031264.5
Plac8
placenta-specific 8
chr8_-_121907678 3.677 ENSMUST00000045557.9
Slc7a5
solute carrier family 7 (cationic amino acid transporter, y+ system), member 5
chr3_-_152340350 3.676 ENSMUST00000073089.6
ENSMUST00000068243.6
Fam73a

family with sequence similarity 73, member A

chr5_+_47984793 3.673 ENSMUST00000170109.2
ENSMUST00000174421.1
ENSMUST00000173702.1
ENSMUST00000173107.1
Slit2



slit homolog 2 (Drosophila)



chr7_-_38107490 3.660 ENSMUST00000108023.3
Ccne1
cyclin E1
chr1_+_166130238 3.648 ENSMUST00000060833.7
ENSMUST00000166159.1
Gpa33

glycoprotein A33 (transmembrane)

chr12_-_28582515 3.646 ENSMUST00000110917.1
ENSMUST00000020965.7
Allc

allantoicase

chr11_+_117782358 3.645 ENSMUST00000117781.1
Tmc8
transmembrane channel-like gene family 8
chr8_-_123983120 3.631 ENSMUST00000075578.6
Abcb10
ATP-binding cassette, sub-family B (MDR/TAP), member 10
chr16_+_10170228 3.607 ENSMUST00000044103.5
Rpl39l
ribosomal protein L39-like
chr7_-_116084635 3.587 ENSMUST00000111755.3
Gm4353
predicted gene 4353
chr16_+_10170216 3.571 ENSMUST00000121292.1
Rpl39l
ribosomal protein L39-like
chr14_+_65806066 3.565 ENSMUST00000139644.1
Pbk
PDZ binding kinase
chr6_+_34354119 3.554 ENSMUST00000038406.6
Akr1b8
aldo-keto reductase family 1, member B8
chr4_+_156109971 3.514 ENSMUST00000072554.6
ENSMUST00000169550.1
ENSMUST00000105576.1
9430015G10Rik


RIKEN cDNA 9430015G10 gene


chr2_+_174415804 3.506 ENSMUST00000109075.1
ENSMUST00000016397.6
Nelfcd

negative elongation factor complex member C/D, Th1l

chr12_+_87816577 3.506 ENSMUST00000110149.1
BB287469
expressed sequence BB287469
chr17_+_6601671 3.486 ENSMUST00000092966.4
Dynlt1c
dynein light chain Tctex-type 1C
chr3_-_27896360 3.484 ENSMUST00000058077.3
Tmem212
transmembrane protein 212
chr11_+_32205411 3.483 ENSMUST00000039601.3
ENSMUST00000149043.1
Snrnp25

small nuclear ribonucleoprotein 25 (U11/U12)

chr17_-_6655939 3.469 ENSMUST00000179554.1
Dynlt1f
dynein light chain Tctex-type 1F
chr15_-_89425856 3.463 ENSMUST00000109313.2
Cpt1b
carnitine palmitoyltransferase 1b, muscle
chr6_-_83527452 3.444 ENSMUST00000141904.1
Actg2
actin, gamma 2, smooth muscle, enteric
chr7_-_99238564 3.427 ENSMUST00000064231.7
Mogat2
monoacylglycerol O-acyltransferase 2
chr11_+_69966896 3.417 ENSMUST00000151515.1
Cldn7
claudin 7
chr11_+_96931387 3.413 ENSMUST00000107633.1
Prr15l
proline rich 15-like
chr10_+_128225830 3.358 ENSMUST00000026455.7
Mip
major intrinsic protein of eye lens fiber
chr4_-_116994354 3.335 ENSMUST00000130273.1
Urod
uroporphyrinogen decarboxylase
chr3_+_129878571 3.325 ENSMUST00000029629.8
Pla2g12a
phospholipase A2, group XIIA
chr5_+_110330697 3.323 ENSMUST00000112481.1
Pole
polymerase (DNA directed), epsilon
chr7_+_28267809 3.316 ENSMUST00000059596.6
Eid2
EP300 interacting inhibitor of differentiation 2
chr7_-_30445508 3.296 ENSMUST00000006828.7
Aplp1
amyloid beta (A4) precursor-like protein 1
chr19_+_4154606 3.290 ENSMUST00000061086.8
Ptprcap
protein tyrosine phosphatase, receptor type, C polypeptide-associated protein
chr6_+_113531675 3.279 ENSMUST00000036340.5
ENSMUST00000101051.2
Fancd2

Fanconi anemia, complementation group D2

chr7_-_118116171 3.275 ENSMUST00000131374.1
Rps15a
ribosomal protein S15A
chr7_-_25297866 3.271 ENSMUST00000148150.1
ENSMUST00000155118.1
Pafah1b3

platelet-activating factor acetylhydrolase, isoform 1b, subunit 3

chr17_+_35067317 3.271 ENSMUST00000173478.1
ENSMUST00000174876.1
Ly6g6c

lymphocyte antigen 6 complex, locus G6C

chr7_+_17087934 3.249 ENSMUST00000152671.1
Psg16
pregnancy specific glycoprotein 16
chr5_+_138280516 3.243 ENSMUST00000048028.8
Stag3
stromal antigen 3
chr6_-_41446062 3.228 ENSMUST00000095999.5
Gm10334
predicted gene 10334
chr6_+_28427789 3.226 ENSMUST00000031719.6
Fscn3
fascin homolog 3, actin-bundling protein, testicular (Strongylocentrotus purpuratus)
chr8_-_105707933 3.218 ENSMUST00000013299.9
Enkd1
enkurin domain containing 1
chr12_-_78980758 3.217 ENSMUST00000174072.1
Tmem229b
transmembrane protein 229B

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
10.4 31.3 GO:0030221 basophil differentiation(GO:0030221)
6.0 17.9 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
4.7 14.1 GO:0070947 neutrophil mediated killing of fungus(GO:0070947)
4.3 13.0 GO:0015811 L-cystine transport(GO:0015811)
3.4 13.8 GO:0035054 embryonic heart tube anterior/posterior pattern specification(GO:0035054)
3.3 10.0 GO:0015828 tyrosine transport(GO:0015828)
3.1 9.2 GO:0070488 neutrophil aggregation(GO:0070488)
3.1 9.2 GO:0071846 actin filament debranching(GO:0071846)
2.7 2.7 GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling(GO:0014068)
2.3 9.4 GO:0015827 tryptophan transport(GO:0015827)
2.3 9.1 GO:0038096 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
2.1 8.6 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
2.1 6.4 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
2.1 12.7 GO:0060931 sinoatrial node cell development(GO:0060931)
2.1 6.3 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
2.0 10.0 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
2.0 7.9 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
1.8 5.5 GO:0002877 regulation of acute inflammatory response to non-antigenic stimulus(GO:0002877) positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
1.8 5.4 GO:1904158 axonemal central apparatus assembly(GO:1904158)
1.8 5.3 GO:0001928 regulation of exocyst assembly(GO:0001928)
1.8 10.5 GO:0046502 uroporphyrinogen III metabolic process(GO:0046502)
1.7 5.2 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
1.7 12.1 GO:0035524 proline transmembrane transport(GO:0035524)
1.7 8.4 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
1.7 10.0 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
1.6 6.6 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
1.6 8.0 GO:1904970 brush border assembly(GO:1904970)
1.5 4.4 GO:1904975 response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976)
1.4 5.7 GO:1990743 protein sialylation(GO:1990743)
1.4 13.9 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
1.4 9.6 GO:0006868 glutamine transport(GO:0006868)
1.4 4.1 GO:0002358 B cell homeostatic proliferation(GO:0002358)
1.3 4.0 GO:0098928 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
1.2 3.7 GO:0021972 corticospinal neuron axon guidance through spinal cord(GO:0021972) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
1.2 12.1 GO:0002553 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
1.2 3.6 GO:0006714 sesquiterpenoid metabolic process(GO:0006714)
1.2 3.5 GO:0046462 monoacylglycerol metabolic process(GO:0046462)
1.1 5.6 GO:0019516 lactate oxidation(GO:0019516)
1.1 3.3 GO:0045004 DNA replication proofreading(GO:0045004)
1.1 6.6 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
1.1 3.3 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
1.1 3.3 GO:0071873 response to norepinephrine(GO:0071873)
1.1 4.2 GO:1902990 mitotic telomere maintenance via semi-conservative replication(GO:1902990)
1.0 6.3 GO:0002838 negative regulation of response to tumor cell(GO:0002835) negative regulation of immune response to tumor cell(GO:0002838)
1.0 3.1 GO:1903490 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
1.0 15.6 GO:0001542 ovulation from ovarian follicle(GO:0001542)
1.0 3.0 GO:0006597 spermine biosynthetic process(GO:0006597)
1.0 3.0 GO:1901074 aminophospholipid transport(GO:0015917) regulation of engulfment of apoptotic cell(GO:1901074)
0.9 4.6 GO:2000680 regulation of rubidium ion transport(GO:2000680)
0.9 2.7 GO:0044868 modulation by host of viral molecular function(GO:0044868) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.9 4.5 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.9 5.3 GO:0070197 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.9 2.6 GO:1903632 positive regulation of aminoacyl-tRNA ligase activity(GO:1903632)
0.9 2.6 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.9 2.6 GO:1904046 seryl-tRNA aminoacylation(GO:0006434) negative regulation of vascular endothelial growth factor production(GO:1904046)
0.8 2.5 GO:1990523 bone regeneration(GO:1990523)
0.8 9.8 GO:0015816 glycine transport(GO:0015816)
0.8 2.4 GO:0003127 detection of nodal flow(GO:0003127) detection of endogenous stimulus(GO:0009726)
0.8 4.0 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.8 4.7 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
0.8 6.3 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.8 11.0 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.8 3.8 GO:0060697 positive regulation of phospholipid catabolic process(GO:0060697)
0.7 3.0 GO:1902340 negative regulation of chromosome condensation(GO:1902340)
0.7 3.7 GO:2000359 regulation of binding of sperm to zona pellucida(GO:2000359)
0.7 1.5 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.7 5.1 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.7 4.3 GO:0060454 positive regulation of gastric acid secretion(GO:0060454)
0.7 18.7 GO:0032460 negative regulation of protein oligomerization(GO:0032460)
0.7 6.3 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.7 2.8 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.7 2.1 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.7 4.8 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.7 1.3 GO:0035444 nickel cation transport(GO:0015675) nickel cation transmembrane transport(GO:0035444)
0.7 3.3 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.6 6.2 GO:0030916 otic vesicle formation(GO:0030916)
0.6 3.1 GO:0032237 activation of store-operated calcium channel activity(GO:0032237)
0.6 2.4 GO:0033580 protein glycosylation at cell surface(GO:0033575) protein galactosylation at cell surface(GO:0033580) protein galactosylation(GO:0042125)
0.6 2.4 GO:1903519 apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.6 1.8 GO:0002355 detection of tumor cell(GO:0002355)
0.6 10.9 GO:0006622 protein targeting to lysosome(GO:0006622)
0.6 2.4 GO:0071772 response to BMP(GO:0071772) cellular response to BMP stimulus(GO:0071773)
0.6 1.2 GO:0019244 lactate biosynthetic process from pyruvate(GO:0019244)
0.6 22.1 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.6 2.9 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912)
0.6 5.2 GO:0003147 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713) cellular response to folic acid(GO:0071231)
0.6 1.7 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.6 2.2 GO:0046351 disaccharide biosynthetic process(GO:0046351)
0.5 2.2 GO:2000426 TRIF-dependent toll-like receptor signaling pathway(GO:0035666) interleukin-4-mediated signaling pathway(GO:0035771) negative regulation of apoptotic cell clearance(GO:2000426)
0.5 2.2 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.5 3.1 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.5 2.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.5 7.2 GO:0043249 erythrocyte maturation(GO:0043249)
0.5 4.6 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.5 2.0 GO:0032696 negative regulation of interleukin-13 production(GO:0032696) trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) odontoblast differentiation(GO:0071895)
0.5 5.5 GO:0071294 cellular response to zinc ion(GO:0071294)
0.5 3.9 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.5 3.3 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.5 2.4 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.5 2.8 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.5 1.8 GO:2000774 positive regulation of cell aging(GO:0090343) positive regulation of cellular senescence(GO:2000774)
0.5 1.8 GO:0051344 negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.5 4.1 GO:1904714 chaperone-mediated autophagy(GO:0061684) regulation of chaperone-mediated autophagy(GO:1904714)
0.5 1.4 GO:0001805 antibody-dependent cellular cytotoxicity(GO:0001788) type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805)
0.5 2.3 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.4 1.3 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.4 1.3 GO:0033189 response to vitamin A(GO:0033189)
0.4 2.1 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.4 1.2 GO:1900149 positive regulation of Schwann cell migration(GO:1900149)
0.4 0.8 GO:0000963 mitochondrial RNA processing(GO:0000963)
0.4 1.2 GO:0036292 DNA rewinding(GO:0036292)
0.4 2.0 GO:0033087 negative regulation of immature T cell proliferation(GO:0033087) regulation of ovarian follicle development(GO:2000354)
0.4 11.1 GO:0042572 retinol metabolic process(GO:0042572)
0.4 4.2 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719)
0.4 1.5 GO:1902896 terminal web assembly(GO:1902896)
0.4 1.2 GO:1905663 response to rapamycin(GO:1901355) regulation of telomerase RNA reverse transcriptase activity(GO:1905661) positive regulation of telomerase RNA reverse transcriptase activity(GO:1905663)
0.4 0.8 GO:0060149 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
0.4 1.1 GO:0060216 definitive hemopoiesis(GO:0060216)
0.4 1.9 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.4 2.6 GO:0086028 bundle of His cell to Purkinje myocyte signaling(GO:0086028) bundle of His cell action potential(GO:0086043)
0.4 3.8 GO:0048563 post-embryonic animal organ morphogenesis(GO:0048563)
0.4 5.2 GO:0015747 urate transport(GO:0015747)
0.4 1.9 GO:0015960 diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966)
0.4 0.4 GO:0042335 cuticle development(GO:0042335)
0.4 6.7 GO:0016075 rRNA catabolic process(GO:0016075)
0.4 1.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.4 1.8 GO:0000103 sulfate assimilation(GO:0000103)
0.4 2.8 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.4 1.1 GO:1903894 regulation of IRE1-mediated unfolded protein response(GO:1903894)
0.3 2.1 GO:0032346 positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349) leading edge cell differentiation(GO:0035026)
0.3 1.4 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.3 1.7 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.3 1.7 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.3 5.7 GO:0006999 nuclear pore organization(GO:0006999)
0.3 2.7 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.3 1.7 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.3 4.6 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.3 3.6 GO:0000255 allantoin metabolic process(GO:0000255)
0.3 1.0 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.3 3.0 GO:0048539 bone marrow development(GO:0048539)
0.3 3.3 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.3 3.3 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.3 1.3 GO:1903896 positive regulation of IRE1-mediated unfolded protein response(GO:1903896)
0.3 1.3 GO:0061386 closure of optic fissure(GO:0061386)
0.3 1.0 GO:0106004 tRNA (guanine-N7)-methylation(GO:0106004)
0.3 1.6 GO:0009597 detection of virus(GO:0009597)
0.3 2.9 GO:0016180 snRNA processing(GO:0016180)
0.3 8.9 GO:1904659 glucose transmembrane transport(GO:1904659)
0.3 0.6 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.3 1.0 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
0.3 4.4 GO:0070269 pyroptosis(GO:0070269)
0.3 1.0 GO:0060623 regulation of chromosome condensation(GO:0060623)
0.3 0.9 GO:1900248 negative regulation of cytoplasmic translational elongation(GO:1900248)
0.3 2.4 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.3 1.8 GO:0018002 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.3 14.4 GO:0043029 T cell homeostasis(GO:0043029)
0.3 4.1 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.3 1.7 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
0.3 1.4 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.3 2.3 GO:0006004 fucose metabolic process(GO:0006004) glycoside catabolic process(GO:0016139)
0.3 3.7 GO:0033004 negative regulation of mast cell activation(GO:0033004)
0.3 1.7 GO:1904667 negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.3 2.2 GO:0042167 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.3 2.2 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.3 4.8 GO:0046599 regulation of centriole replication(GO:0046599)
0.3 0.8 GO:0030450 regulation of complement activation, classical pathway(GO:0030450)
0.3 1.6 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.3 1.1 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.3 5.4 GO:0031297 replication fork processing(GO:0031297)
0.3 2.6 GO:1902969 mitotic DNA replication(GO:1902969)
0.3 3.1 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.3 0.8 GO:1904978 regulation of endosome organization(GO:1904978) positive regulation of endosome organization(GO:1904980)
0.3 2.3 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.3 8.8 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.3 1.8 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
0.2 1.2 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.2 0.5 GO:0002884 negative regulation of acute inflammatory response to antigenic stimulus(GO:0002865) negative regulation of hypersensitivity(GO:0002884)
0.2 0.7 GO:0009233 menaquinone metabolic process(GO:0009233)
0.2 2.2 GO:0008343 adult feeding behavior(GO:0008343)
0.2 1.0 GO:2001270 regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.2 2.5 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.2 0.5 GO:0007000 nucleolus organization(GO:0007000)
0.2 0.7 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.2 0.5 GO:0032849 regulation of cellular pH reduction(GO:0032847) positive regulation of cellular pH reduction(GO:0032849)
0.2 0.5 GO:0002339 B cell selection(GO:0002339) peripheral B cell selection(GO:0002343) B cell affinity maturation(GO:0002344)
0.2 1.6 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.2 0.9 GO:0035547 interferon-beta secretion(GO:0035546) regulation of interferon-beta secretion(GO:0035547) positive regulation of interferon-beta secretion(GO:0035549)
0.2 6.8 GO:0097503 sialylation(GO:0097503)
0.2 0.9 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.2 0.7 GO:0046166 glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.2 0.9 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.2 0.4 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
0.2 1.2 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.2 0.6 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160)
0.2 1.4 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.2 0.6 GO:0072139 glomerular parietal epithelial cell differentiation(GO:0072139)
0.2 5.1 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.2 0.8 GO:0018201 peptidyl-glycine modification(GO:0018201)
0.2 1.6 GO:0019614 catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.2 1.0 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.2 1.0 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.2 1.2 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.2 1.4 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.2 3.1 GO:0001865 NK T cell differentiation(GO:0001865)
0.2 0.4 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.2 2.1 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.2 0.8 GO:0030576 Cajal body organization(GO:0030576)
0.2 1.3 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.2 1.1 GO:0018094 protein polyglycylation(GO:0018094)
0.2 1.5 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
0.2 1.1 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.2 0.9 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.2 2.0 GO:2001204 regulation of osteoclast development(GO:2001204)
0.2 4.0 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.2 1.4 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.2 1.1 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.2 2.5 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.2 2.5 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.2 0.4 GO:0071347 cellular response to interleukin-1(GO:0071347)
0.2 1.8 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.2 1.8 GO:0042989 sequestering of actin monomers(GO:0042989)
0.2 3.5 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.2 0.7 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.2 1.1 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.2 8.9 GO:0045332 phospholipid translocation(GO:0045332)
0.2 1.5 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.2 3.4 GO:0006833 water transport(GO:0006833)
0.2 1.1 GO:1904688 regulation of cytoplasmic translational initiation(GO:1904688)
0.2 2.7 GO:0030049 muscle filament sliding(GO:0030049)
0.2 1.6 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.2 0.3 GO:0034136 detection of peptidoglycan(GO:0032499) negative regulation of interleukin-18 production(GO:0032701) negative regulation of toll-like receptor 2 signaling pathway(GO:0034136)
0.2 0.8 GO:0042148 strand invasion(GO:0042148)
0.2 1.4 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.2 0.5 GO:0090220 telomere localization(GO:0034397) chromosome localization to nuclear envelope involved in homologous chromosome segregation(GO:0090220)
0.2 6.4 GO:0040001 establishment of mitotic spindle localization(GO:0040001)
0.2 0.3 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.2 1.5 GO:0035878 nail development(GO:0035878)
0.2 5.5 GO:1903963 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.2 0.9 GO:0034227 tRNA thio-modification(GO:0034227)
0.1 1.6 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 2.0 GO:0033623 regulation of integrin activation(GO:0033623)
0.1 0.4 GO:0009624 response to nematode(GO:0009624)
0.1 2.2 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.1 5.5 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.1 3.8 GO:0006706 steroid catabolic process(GO:0006706)
0.1 0.4 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.1 0.4 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.1 0.8 GO:0003105 negative regulation of glomerular filtration(GO:0003105)
0.1 1.9 GO:0036065 fucosylation(GO:0036065)
0.1 1.3 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.1 4.5 GO:0006270 DNA replication initiation(GO:0006270)
0.1 0.6 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.1 0.8 GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.1 0.4 GO:0070898 RNA polymerase III transcriptional preinitiation complex assembly(GO:0070898)
0.1 6.1 GO:0016572 histone phosphorylation(GO:0016572)
0.1 0.6 GO:1900095 regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.1 0.4 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
0.1 0.4 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.1 1.2 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.1 2.6 GO:0045787 positive regulation of cell cycle(GO:0045787)
0.1 2.0 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.1 1.0 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291)
0.1 0.8 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.1 1.5 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.1 1.4 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.1 1.1 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 1.7 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.1 5.0 GO:0031110 regulation of microtubule polymerization or depolymerization(GO:0031110)
0.1 3.3 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.1 0.8 GO:0051025 negative regulation of immunoglobulin secretion(GO:0051025)
0.1 6.2 GO:0002181 cytoplasmic translation(GO:0002181)
0.1 0.7 GO:0036337 Fas signaling pathway(GO:0036337)
0.1 1.3 GO:0099628 receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
0.1 0.3 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.1 0.9 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 1.3 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.1 2.6 GO:0050817 blood coagulation(GO:0007596) hemostasis(GO:0007599) coagulation(GO:0050817)
0.1 4.0 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.1 1.3 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.1 1.9 GO:0019532 oxalate transport(GO:0019532)
0.1 0.6 GO:0036006 response to macrophage colony-stimulating factor(GO:0036005) cellular response to macrophage colony-stimulating factor stimulus(GO:0036006)
0.1 0.2 GO:0060557 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.1 4.2 GO:0007140 male meiotic nuclear division(GO:0007140)
0.1 0.3 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.1 0.8 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.1 3.0 GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.1 2.0 GO:0002755 MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.1 5.0 GO:0000266 mitochondrial fission(GO:0000266)
0.1 0.5 GO:0010796 regulation of multivesicular body size(GO:0010796)
0.1 1.2 GO:0071360 cellular response to exogenous dsRNA(GO:0071360)
0.1 1.2 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.1 0.4 GO:0002636 positive regulation of germinal center formation(GO:0002636)
0.1 2.0 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.1 0.5 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.1 3.3 GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032435)
0.1 1.0 GO:0035646 endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
0.1 0.3 GO:0006301 postreplication repair(GO:0006301)
0.1 5.4 GO:0007019 microtubule depolymerization(GO:0007019)
0.1 0.3 GO:0060744 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.1 2.7 GO:0030071 regulation of mitotic metaphase/anaphase transition(GO:0030071)
0.1 0.6 GO:0001905 activation of membrane attack complex(GO:0001905) regulation of activation of membrane attack complex(GO:0001969)
0.1 0.5 GO:0060763 mammary duct terminal end bud growth(GO:0060763)
0.1 1.0 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.1 1.6 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.1 1.0 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.1 1.6 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.1 1.6 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 1.9 GO:0035855 megakaryocyte development(GO:0035855)
0.1 0.2 GO:0021764 amygdala development(GO:0021764)
0.1 0.2 GO:0006624 vacuolar protein processing(GO:0006624)
0.1 0.4 GO:0071104 response to interleukin-9(GO:0071104)
0.1 0.2 GO:0050883 musculoskeletal movement, spinal reflex action(GO:0050883)
0.1 1.6 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.1 0.7 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.1 0.3 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.1 0.3 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.1 1.7 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.1 0.1 GO:0071726 response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726)
0.1 0.6 GO:0071280 cellular response to copper ion(GO:0071280)
0.1 2.1 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1 0.3 GO:1902336 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) positive regulation of retinal ganglion cell axon guidance(GO:1902336)
0.1 1.3 GO:0006144 purine nucleobase metabolic process(GO:0006144)
0.1 0.2 GO:0071314 cellular response to cocaine(GO:0071314)
0.1 0.1 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.1 1.4 GO:0071364 response to epidermal growth factor(GO:0070849) cellular response to epidermal growth factor stimulus(GO:0071364)
0.1 0.5 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.1 0.5 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.1 1.3 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.1 0.7 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.1 0.4 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.1 0.5 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.1 0.3 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.1 0.3 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.1 1.0 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.1 1.6 GO:0016486 peptide hormone processing(GO:0016486)
0.1 0.2 GO:0034421 post-translational protein acetylation(GO:0034421)
0.1 0.2 GO:1990000 amyloid fibril formation(GO:1990000)
0.1 1.6 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.1 0.9 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.1 4.2 GO:0001824 blastocyst development(GO:0001824)
0.1 1.1 GO:0060325 head morphogenesis(GO:0060323) face morphogenesis(GO:0060325)
0.1 1.5 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 0.5 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.1 0.8 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.1 0.6 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.1 3.1 GO:0016925 protein sumoylation(GO:0016925)
0.1 1.6 GO:0019731 antibacterial humoral response(GO:0019731)
0.1 0.5 GO:0006449 regulation of translational termination(GO:0006449)
0.1 0.8 GO:0051493 regulation of cytoskeleton organization(GO:0051493)
0.1 1.1 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.1 3.4 GO:0002088 lens development in camera-type eye(GO:0002088)
0.1 0.5 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
0.1 1.0 GO:0032508 DNA duplex unwinding(GO:0032508)
0.1 0.3 GO:0046103 ADP biosynthetic process(GO:0006172) inosine biosynthetic process(GO:0046103)
0.1 1.2 GO:0060009 Sertoli cell development(GO:0060009)
0.1 0.3 GO:0016266 O-glycan processing(GO:0016266)
0.1 3.5 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.1 0.5 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.1 3.7 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.1 0.5 GO:0030534 adult behavior(GO:0030534)
0.1 0.6 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.1 0.6 GO:0030220 platelet formation(GO:0030220) platelet morphogenesis(GO:0036344)
0.1 1.2 GO:0030225 macrophage differentiation(GO:0030225)
0.1 0.6 GO:0010666 positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.0 0.4 GO:0090043 tubulin deacetylation(GO:0090042) regulation of tubulin deacetylation(GO:0090043)
0.0 0.8 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.6 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 2.9 GO:0007088 regulation of mitotic nuclear division(GO:0007088)
0.0 0.8 GO:1990090 response to nerve growth factor(GO:1990089) cellular response to nerve growth factor stimulus(GO:1990090)
0.0 2.6 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.6 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.5 GO:0051974 negative regulation of telomerase activity(GO:0051974)
0.0 1.7 GO:0009214 cyclic nucleotide catabolic process(GO:0009214)
0.0 0.3 GO:0097421 liver regeneration(GO:0097421)
0.0 0.4 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 1.8 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.6 GO:0060632 regulation of microtubule-based movement(GO:0060632)
0.0 0.2 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 4.0 GO:1901379 regulation of potassium ion transmembrane transport(GO:1901379)
0.0 0.9 GO:0051225 spindle assembly(GO:0051225)
0.0 1.2 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.5 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.4 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 5.8 GO:0008360 regulation of cell shape(GO:0008360)
0.0 1.2 GO:0014003 oligodendrocyte development(GO:0014003)
0.0 0.3 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.3 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 1.9 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 0.7 GO:0002250 adaptive immune response(GO:0002250)
0.0 1.3 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 1.0 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.2 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.2 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.2 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 1.7 GO:0046324 regulation of glucose import(GO:0046324)
0.0 1.1 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 1.9 GO:0006364 rRNA processing(GO:0006364)
0.0 1.2 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.0 0.3 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.3 GO:0009068 aspartate family amino acid catabolic process(GO:0009068)
0.0 0.3 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.5 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.1 GO:0033685 negative regulation of luteinizing hormone secretion(GO:0033685)
0.0 0.5 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0 0.3 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.3 GO:2000580 regulation of microtubule motor activity(GO:2000574) positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.3 GO:0070542 response to fatty acid(GO:0070542)
0.0 0.6 GO:0006469 negative regulation of protein kinase activity(GO:0006469)
0.0 0.9 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.3 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.3 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 1.8 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.1 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.0 1.0 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.0 0.1 GO:0016598 protein arginylation(GO:0016598)
0.0 0.2 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.5 GO:0006801 superoxide metabolic process(GO:0006801)
0.0 0.8 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 1.0 GO:0046579 positive regulation of Ras protein signal transduction(GO:0046579)
0.0 0.1 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 1.4 GO:0071901 negative regulation of protein serine/threonine kinase activity(GO:0071901)
0.0 0.7 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 0.3 GO:0050919 negative chemotaxis(GO:0050919)
0.0 4.2 GO:0043588 skin development(GO:0043588)
0.0 0.3 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.0 1.5 GO:0099132 ATP hydrolysis coupled cation transmembrane transport(GO:0099132)
0.0 0.1 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.0 0.5 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.3 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 1.0 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.3 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.0 0.1 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 1.0 GO:0048477 oogenesis(GO:0048477)
0.0 1.5 GO:0044070 regulation of anion transport(GO:0044070)
0.0 0.4 GO:0048266 behavioral response to pain(GO:0048266)
0.0 5.5 GO:0006470 protein dephosphorylation(GO:0006470)
0.0 1.0 GO:0003341 cilium movement(GO:0003341)
0.0 0.2 GO:0031639 plasminogen activation(GO:0031639)
0.0 0.6 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 1.1 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.2 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.2 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.4 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.0 0.2 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.7 GO:0007346 regulation of mitotic cell cycle(GO:0007346)
0.0 2.1 GO:0032496 response to lipopolysaccharide(GO:0032496)
0.0 0.2 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.4 GO:0042509 regulation of tyrosine phosphorylation of STAT protein(GO:0042509)
0.0 0.2 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.3 GO:0001782 B cell homeostasis(GO:0001782)
0.0 0.6 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 1.2 GO:0031497 chromatin assembly(GO:0031497)
0.0 0.1 GO:0016445 somatic diversification of immunoglobulins(GO:0016445)
0.0 0.2 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.5 GO:0007059 chromosome segregation(GO:0007059)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
4.5 17.9 GO:0031095 platelet dense tubular network membrane(GO:0031095)
2.8 13.8 GO:0032444 activin responsive factor complex(GO:0032444)
2.4 19.3 GO:0005664 nuclear origin of replication recognition complex(GO:0005664)
1.8 5.4 GO:0035101 FACT complex(GO:0035101)
1.5 4.6 GO:0046691 intracellular canaliculus(GO:0046691)
1.5 4.4 GO:0034774 secretory granule lumen(GO:0034774) cytoplasmic vesicle lumen(GO:0060205)
1.3 4.0 GO:1990257 piccolo-bassoon transport vesicle(GO:1990257)
1.2 4.6 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
1.1 9.0 GO:0001940 male pronucleus(GO:0001940)
1.1 4.5 GO:0014802 terminal cisterna(GO:0014802)
1.0 3.1 GO:0031510 SUMO activating enzyme complex(GO:0031510)
1.0 4.1 GO:0097450 astrocyte end-foot(GO:0097450)
1.0 3.9 GO:0032021 NELF complex(GO:0032021)
0.9 5.6 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.9 16.8 GO:0005652 nuclear lamina(GO:0005652)
0.9 4.4 GO:0000235 astral microtubule(GO:0000235)
0.8 16.6 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.8 11.5 GO:0044754 autolysosome(GO:0044754)
0.8 8.0 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.8 13.9 GO:0031616 spindle pole centrosome(GO:0031616)
0.7 2.9 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.7 6.3 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.7 2.1 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.7 3.3 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.6 4.4 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.6 1.7 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.5 2.1 GO:0070022 transforming growth factor beta receptor complex(GO:0070022)
0.5 7.8 GO:0032039 integrator complex(GO:0032039)
0.5 2.4 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.5 2.9 GO:1990393 3M complex(GO:1990393)
0.5 1.9 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.5 6.0 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.5 36.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.5 6.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.4 4.9 GO:0043020 NADPH oxidase complex(GO:0043020)
0.4 2.2 GO:0044611 nuclear pore inner ring(GO:0044611)
0.4 1.8 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.4 6.5 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.4 12.1 GO:0001891 phagocytic cup(GO:0001891)
0.4 0.8 GO:0070557 PCNA-p21 complex(GO:0070557)
0.4 20.3 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.4 3.4 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.4 1.8 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.3 3.1 GO:1990023 mitotic spindle midzone(GO:1990023)
0.3 3.8 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.3 1.7 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.3 1.4 GO:0120001 apical plasma membrane urothelial plaque(GO:0120001)
0.3 11.7 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.3 1.0 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.3 42.6 GO:0017053 transcriptional repressor complex(GO:0017053)
0.3 1.3 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.3 1.2 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.3 3.1 GO:0031080 nuclear pore outer ring(GO:0031080)
0.3 1.2 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.3 2.0 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.3 2.9 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.3 4.0 GO:0090543 Flemming body(GO:0090543)
0.3 5.1 GO:0032426 stereocilium tip(GO:0032426)
0.3 8.2 GO:0097228 sperm principal piece(GO:0097228)
0.3 0.8 GO:1990047 spindle matrix(GO:1990047)
0.3 0.5 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.2 1.2 GO:0071797 LUBAC complex(GO:0071797)
0.2 1.2 GO:0044316 cone cell pedicle(GO:0044316)
0.2 1.7 GO:0019815 B cell receptor complex(GO:0019815)
0.2 1.7 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.2 1.7 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.2 3.4 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.2 1.4 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.2 1.8 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.2 2.1 GO:0031415 NatA complex(GO:0031415)
0.2 5.0 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.2 3.6 GO:0036387 origin recognition complex(GO:0000808) GINS complex(GO:0000811) nuclear pre-replicative complex(GO:0005656) DNA replication preinitiation complex(GO:0031261) pre-replicative complex(GO:0036387)
0.2 5.3 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.2 14.5 GO:0042629 mast cell granule(GO:0042629)
0.2 1.5 GO:0005796 Golgi lumen(GO:0005796)
0.2 1.2 GO:0031258 lamellipodium membrane(GO:0031258)
0.2 10.6 GO:0005871 kinesin complex(GO:0005871)
0.2 2.0 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.2 1.7 GO:0002177 manchette(GO:0002177)
0.2 0.7 GO:0030891 VCB complex(GO:0030891)
0.2 1.8 GO:0042788 polysomal ribosome(GO:0042788)
0.2 1.2 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.2 0.8 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.2 1.8 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 1.0 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1 1.2 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.1 2.8 GO:0031527 filopodium membrane(GO:0031527)
0.1 3.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 0.3 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.1 3.5 GO:0042575 DNA polymerase complex(GO:0042575)
0.1 0.1 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.1 3.1 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 2.3 GO:0031528 microvillus membrane(GO:0031528)
0.1 15.8 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 3.4 GO:0097526 spliceosomal tri-snRNP complex(GO:0097526)
0.1 1.0 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 0.8 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.1 1.3 GO:0070545 PeBoW complex(GO:0070545)
0.1 0.6 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 1.9 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 0.4 GO:0000814 ESCRT II complex(GO:0000814)
0.1 1.3 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 1.5 GO:0035253 ciliary rootlet(GO:0035253)
0.1 0.6 GO:0071914 prominosome(GO:0071914)
0.1 1.0 GO:0042382 paraspeckles(GO:0042382)
0.1 3.7 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.1 0.7 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.1 1.1 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 1.8 GO:0033202 DNA helicase complex(GO:0033202)
0.1 1.5 GO:0071011 precatalytic spliceosome(GO:0071011)
0.1 0.9 GO:0070652 HAUS complex(GO:0070652)
0.1 1.5 GO:0001527 microfibril(GO:0001527)
0.1 6.3 GO:0031941 filamentous actin(GO:0031941)
0.1 0.3 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.1 1.1 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.1 0.8 GO:0000502 proteasome complex(GO:0000502) endopeptidase complex(GO:1905369)
0.1 2.6 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 1.5 GO:0032433 filopodium tip(GO:0032433)
0.1 0.4 GO:0016342 catenin complex(GO:0016342)
0.1 4.5 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.1 2.1 GO:0030914 STAGA complex(GO:0030914)
0.1 0.6 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.1 3.4 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 0.5 GO:0033010 paranodal junction(GO:0033010)
0.1 1.4 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.1 8.4 GO:0031526 brush border membrane(GO:0031526)
0.1 2.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 1.5 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 2.9 GO:0002080 acrosomal membrane(GO:0002080)
0.1 0.8 GO:0032009 early phagosome(GO:0032009)
0.1 1.9 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 0.7 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 5.7 GO:0005643 nuclear pore(GO:0005643)
0.1 1.2 GO:0005916 fascia adherens(GO:0005916)
0.1 1.1 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.1 2.4 GO:0031985 Golgi cisterna(GO:0031985)
0.1 4.7 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 3.0 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 1.0 GO:0042555 MCM complex(GO:0042555) MCM core complex(GO:0097373)
0.1 1.8 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 2.1 GO:0032982 myosin filament(GO:0032982)
0.1 16.5 GO:0031965 nuclear membrane(GO:0031965)
0.1 0.7 GO:0031209 SCAR complex(GO:0031209)
0.1 1.8 GO:0098573 integral component of mitochondrial membrane(GO:0032592) intrinsic component of mitochondrial membrane(GO:0098573)
0.1 6.8 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 6.3 GO:0036156 inner dynein arm(GO:0036156)
0.1 2.4 GO:0043198 dendritic shaft(GO:0043198)
0.1 3.1 GO:0034704 calcium channel complex(GO:0034704)
0.1 4.9 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 0.3 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.1 5.7 GO:0032587 ruffle membrane(GO:0032587)
0.1 0.5 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 7.5 GO:0042383 sarcolemma(GO:0042383)
0.1 1.4 GO:0014704 intercalated disc(GO:0014704)
0.1 7.1 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.1 0.5 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 1.4 GO:0060170 ciliary membrane(GO:0060170)
0.1 0.2 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.1 1.3 GO:0015030 Cajal body(GO:0015030)
0.1 1.2 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.1 1.5 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.5 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 1.2 GO:0001741 XY body(GO:0001741)
0.0 4.6 GO:0016605 PML body(GO:0016605)
0.0 60.8 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 2.9 GO:0031514 motile cilium(GO:0031514)
0.0 0.4 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.4 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189)
0.0 0.3 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 1.2 GO:0090544 BAF-type complex(GO:0090544)
0.0 0.3 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.3 GO:0099078 BORC complex(GO:0099078)
0.0 1.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.7 GO:0030686 90S preribosome(GO:0030686)
0.0 0.5 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.6 GO:0034455 t-UTP complex(GO:0034455)
0.0 0.1 GO:0005798 Golgi-associated vesicle(GO:0005798)
0.0 1.4 GO:0008180 COP9 signalosome(GO:0008180)
0.0 1.8 GO:0019898 extrinsic component of membrane(GO:0019898)
0.0 1.1 GO:0016592 mediator complex(GO:0016592) core mediator complex(GO:0070847)
0.0 0.3 GO:0097346 INO80-type complex(GO:0097346)
0.0 0.3 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 3.7 GO:0043679 axon terminus(GO:0043679)
0.0 0.6 GO:0016235 aggresome(GO:0016235)
0.0 6.8 GO:0005925 focal adhesion(GO:0005925)
0.0 0.8 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 1.4 GO:0005776 autophagosome(GO:0005776)
0.0 0.9 GO:0000786 nucleosome(GO:0000786)
0.0 1.6 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.8 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 1.2 GO:0005840 ribosome(GO:0005840)
0.0 0.7 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.5 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 2.2 GO:0005768 endosome(GO:0005768)
0.0 0.3 GO:0005861 troponin complex(GO:0005861)
0.0 0.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 1.3 GO:0000776 kinetochore(GO:0000776)
0.0 0.1 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.6 GO:0030426 growth cone(GO:0030426)
0.0 0.9 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.4 GO:0097546 ciliary base(GO:0097546)
0.0 0.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834) GTPase complex(GO:1905360)
0.0 0.3 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.1 GO:0002102 podosome(GO:0002102)
0.0 0.0 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.0 0.4 GO:0001533 cornified envelope(GO:0001533)
0.0 0.1 GO:0030136 clathrin-coated vesicle(GO:0030136)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
8.6 8.6 GO:0003882 CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:0003882)
4.3 13.0 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
3.9 15.6 GO:0004566 beta-glucuronidase activity(GO:0004566)
3.3 10.0 GO:0005302 L-tyrosine transmembrane transporter activity(GO:0005302)
2.1 6.2 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
2.0 10.0 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
2.0 13.7 GO:0016936 galactoside binding(GO:0016936)
1.7 37.6 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
1.7 16.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
1.6 6.6 GO:0004568 chitinase activity(GO:0004568)
1.5 9.3 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
1.5 4.6 GO:0070401 NADP+ binding(GO:0070401)
1.5 12.1 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
1.4 5.7 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
1.4 12.4 GO:0004882 androgen receptor activity(GO:0004882)
1.3 9.4 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
1.3 10.5 GO:0050786 RAGE receptor binding(GO:0050786)
1.3 7.8 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
1.2 1.2 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
1.2 6.2 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
1.2 6.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
1.2 6.0 GO:0030171 voltage-gated proton channel activity(GO:0030171)
1.1 12.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
1.0 3.0 GO:0030226 aminophospholipid transporter activity(GO:0015247) apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
1.0 8.8 GO:0008865 fructokinase activity(GO:0008865)
1.0 5.7 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
1.0 8.6 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.9 5.5 GO:0042731 PH domain binding(GO:0042731)
0.9 3.5 GO:0004825 methionine-tRNA ligase activity(GO:0004825)
0.9 13.9 GO:0003688 DNA replication origin binding(GO:0003688)
0.9 2.6 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.9 6.8 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.8 3.3 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.8 7.7 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.8 2.3 GO:0015928 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.7 2.2 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.7 8.9 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.7 2.2 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.7 9.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.7 2.8 GO:0004074 biliverdin reductase activity(GO:0004074)
0.7 3.4 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.7 1.3 GO:0015099 nickel cation transmembrane transporter activity(GO:0015099)
0.7 11.1 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.6 1.8 GO:0036004 GAF domain binding(GO:0036004)
0.6 4.8 GO:0005499 vitamin D binding(GO:0005499)
0.6 7.0 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) L-serine transporter activity(GO:1905361)
0.6 2.9 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.6 4.5 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.5 1.6 GO:0016206 catechol O-methyltransferase activity(GO:0016206) L-dopa O-methyltransferase activity(GO:0102084)
0.5 3.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.5 3.6 GO:0001758 retinal dehydrogenase activity(GO:0001758) alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.5 7.1 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.5 1.4 GO:0097644 calcitonin receptor activity(GO:0004948) calcitonin binding(GO:0032841) calcitonin family binding(GO:0097644)
0.5 1.9 GO:0038025 reelin receptor activity(GO:0038025)
0.5 2.4 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.5 9.6 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.5 3.2 GO:1990948 ubiquitin ligase inhibitor activity(GO:1990948)
0.4 12.6 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.4 1.3 GO:0032190 acrosin binding(GO:0032190)
0.4 2.5 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.4 1.3 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.4 1.7 GO:0050436 microfibril binding(GO:0050436)
0.4 5.0 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.4 3.3 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.4 4.5 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.4 2.4 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.4 14.3 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.4 1.1 GO:0070736 protein-glycine ligase activity, initiating(GO:0070736)
0.4 4.9 GO:0016004 phospholipase activator activity(GO:0016004)
0.4 2.9 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.4 2.2 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.4 14.1 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.4 1.4 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.4 1.1 GO:0045340 mercury ion binding(GO:0045340)
0.4 2.1 GO:0004985 opioid receptor activity(GO:0004985)
0.4 2.8 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.3 5.2 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.3 2.7 GO:0001849 complement component C1q binding(GO:0001849)
0.3 1.4 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.3 3.1 GO:0044388 small protein activating enzyme binding(GO:0044388)
0.3 2.7 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.3 4.6 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907) G-protein coupled neurotransmitter receptor activity(GO:0099528)
0.3 7.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.3 1.0 GO:0008176 tRNA (guanine-N7-)-methyltransferase activity(GO:0008176)
0.3 1.0 GO:0052593 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.3 2.2 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.3 1.6 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.3 0.9 GO:0098770 FBXO family protein binding(GO:0098770)
0.3 2.1 GO:0031013 calcium-dependent ATPase activity(GO:0030899) troponin I binding(GO:0031013)
0.3 1.8 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.3 1.5 GO:0008422 beta-glucosidase activity(GO:0008422)
0.3 3.0 GO:0016918 retinal binding(GO:0016918)
0.3 13.3 GO:0030552 cAMP binding(GO:0030552)
0.3 2.7 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.3 1.2 GO:0003721 telomerase RNA reverse transcriptase activity(GO:0003721)
0.3 6.1 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.3 1.1 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.3 1.7 GO:0097016 L27 domain binding(GO:0097016)
0.3 1.4 GO:0030620 U2 snRNA binding(GO:0030620)
0.3 1.4 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.3 16.9 GO:0030507 spectrin binding(GO:0030507)
0.3 1.4 GO:0019770 IgG receptor activity(GO:0019770)
0.3 1.8 GO:0004027 alcohol sulfotransferase activity(GO:0004027)
0.3 0.8 GO:0070140 ubiquitin-like protein-specific isopeptidase activity(GO:0070138) SUMO-specific isopeptidase activity(GO:0070140)
0.3 46.2 GO:0003735 structural constituent of ribosome(GO:0003735)
0.3 4.1 GO:0002162 dystroglycan binding(GO:0002162)
0.3 2.3 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.2 2.7 GO:0051870 methotrexate binding(GO:0051870)
0.2 1.5 GO:0019211 phosphatase activator activity(GO:0019211)
0.2 5.1 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.2 1.5 GO:0032051 clathrin light chain binding(GO:0032051)
0.2 4.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.2 1.7 GO:0032184 SUMO polymer binding(GO:0032184)
0.2 1.2 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.2 0.7 GO:0071553 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.2 6.4 GO:0045503 dynein light chain binding(GO:0045503)
0.2 1.1 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.2 6.8 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.2 1.8 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.2 2.5 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.2 4.7 GO:0031005 filamin binding(GO:0031005)
0.2 6.3 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.2 5.0 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.2 0.6 GO:0034618 arginine binding(GO:0034618)
0.2 2.4 GO:0050897 cobalt ion binding(GO:0050897)
0.2 4.2 GO:0030275 LRR domain binding(GO:0030275)
0.2 5.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.2 1.8 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.2 0.8 GO:0016842 amidine-lyase activity(GO:0016842)
0.2 1.4 GO:0019808 polyamine binding(GO:0019808)
0.2 0.8 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.2 0.4 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.2 0.6 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.2 5.0 GO:0070182 DNA polymerase binding(GO:0070182)
0.2 14.5 GO:0097110 scaffold protein binding(GO:0097110)
0.2 2.5 GO:0004806 triglyceride lipase activity(GO:0004806)
0.2 1.6 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.2 0.5 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.2 6.2 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.2 1.3 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365)
0.2 4.7 GO:0030291 protein serine/threonine kinase inhibitor activity(GO:0030291)
0.2 2.8 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.2 0.5 GO:0042015 interleukin-20 binding(GO:0042015)
0.2 0.8 GO:0045504 dynein heavy chain binding(GO:0045504)
0.2 11.0 GO:0043022 ribosome binding(GO:0043022)
0.2 1.8 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.2 9.6 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.2 1.5 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.2 4.8 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.2 7.2 GO:0050699 WW domain binding(GO:0050699)
0.2 0.8 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.2 1.4 GO:0070034 telomerase RNA binding(GO:0070034)
0.2 0.8 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 0.9 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.1 1.2 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 3.2 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 3.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.4 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 1.0 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.1 1.4 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.1 0.6 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.1 1.2 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.1 6.6 GO:0042169 SH2 domain binding(GO:0042169)
0.1 3.3 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.1 1.2 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 0.8 GO:0000150 recombinase activity(GO:0000150)
0.1 0.4 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1 0.5 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 2.8 GO:0043274 phospholipase binding(GO:0043274)
0.1 13.6 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1 1.2 GO:0036310 annealing helicase activity(GO:0036310)
0.1 0.4 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.1 1.1 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.1 2.3 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 1.4 GO:0050811 GABA receptor binding(GO:0050811)
0.1 0.4 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.1 0.5 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.1 1.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 1.9 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 0.6 GO:0030250 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.1 0.6 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 1.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.3 GO:0001032 RNA polymerase III type 3 promoter DNA binding(GO:0001032)
0.1 0.8 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1 3.9 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 2.1 GO:0008373 sialyltransferase activity(GO:0008373)
0.1 1.5 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 1.3 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 0.3 GO:0050220 MAP kinase activity involved in innate immune response(GO:0038075) prostaglandin-E synthase activity(GO:0050220)
0.1 1.5 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 0.4 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 1.2 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.1 3.3 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 0.3 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
0.1 0.5 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 3.1 GO:0008198 ferrous iron binding(GO:0008198)
0.1 1.1 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 1.3 GO:0070628 proteasome binding(GO:0070628)
0.1 3.7 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 2.1 GO:0000146 microfilament motor activity(GO:0000146)
0.1 1.0 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 2.9 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.1 1.9 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.1 2.2 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 1.8 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 1.7 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 2.6 GO:0008235 metalloexopeptidase activity(GO:0008235)
0.1 2.1 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 1.0 GO:0043495 protein membrane anchor(GO:0043495)
0.1 0.3 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.1 1.7 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 0.4 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.1 1.3 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.1 1.2 GO:0030551 cyclic nucleotide binding(GO:0030551)
0.1 3.5 GO:0003777 microtubule motor activity(GO:0003777)
0.1 0.5 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.1 0.3 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 1.9 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.1 4.1 GO:0031490 chromatin DNA binding(GO:0031490)
0.1 0.3 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.1 1.3 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.1 0.3 GO:0008097 5S rRNA binding(GO:0008097)
0.1 0.9 GO:0004000 adenosine deaminase activity(GO:0004000)
0.1 1.9 GO:0097718 disordered domain specific binding(GO:0097718)
0.1 0.8 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 0.3 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 2.7 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 0.3 GO:0106017 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) phosphatidylinositol-3,4-bisphosphate phosphatase activity(GO:0106017)
0.1 0.8 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 1.4 GO:0016594 glycine binding(GO:0016594)
0.1 0.4 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 0.4 GO:0070492 oligosaccharide binding(GO:0070492)
0.1 2.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 0.4 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.1 3.3 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 0.2 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 2.3 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.1 0.1 GO:0001129 RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
0.1 1.4 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 4.1 GO:0140034 methylated histone binding(GO:0035064) methylation-dependent protein binding(GO:0140034)
0.1 0.4 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 1.2 GO:0070840 dynein complex binding(GO:0070840)
0.1 1.0 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 0.6 GO:0004526 ribonuclease P activity(GO:0004526)
0.1 1.0 GO:0043422 protein kinase B binding(GO:0043422)
0.1 2.4 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 1.7 GO:0003684 damaged DNA binding(GO:0003684)
0.1 2.4 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 3.1 GO:0005518 collagen binding(GO:0005518)
0.1 0.4 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 6.6 GO:0047485 protein N-terminus binding(GO:0047485)
0.1 2.3 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 2.8 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.1 4.2 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 1.8 GO:0003785 actin monomer binding(GO:0003785)
0.0 1.0 GO:0019843 rRNA binding(GO:0019843)
0.0 0.2 GO:0061733 peptide-lysine-N-acetyltransferase activity(GO:0061733)
0.0 0.4 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 1.4 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.0 0.4 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 1.9 GO:0004520 endodeoxyribonuclease activity(GO:0004520)
0.0 2.4 GO:0002039 p53 binding(GO:0002039)
0.0 0.9 GO:0030295 protein kinase activator activity(GO:0030295)
0.0 0.3 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 1.3 GO:0005112 Notch binding(GO:0005112)
0.0 2.6 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.4 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 1.2 GO:0046332 SMAD binding(GO:0046332)
0.0 0.8 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.2 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 1.0 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 1.1 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 2.0 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 5.1 GO:0042393 histone binding(GO:0042393)
0.0 19.1 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 0.7 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 1.8 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.1 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.0 0.6 GO:0005521 lamin binding(GO:0005521)
0.0 1.4 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.8 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.6 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 2.1 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 5.9 GO:0008017 microtubule binding(GO:0008017)
0.0 1.0 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 4.4 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.5 GO:0003690 double-stranded DNA binding(GO:0003690)
0.0 0.5 GO:0001848 complement binding(GO:0001848)
0.0 0.8 GO:0042054 histone methyltransferase activity(GO:0042054)
0.0 0.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 6.9 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.0 0.8 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.5 GO:0004620 phospholipase activity(GO:0004620)
0.0 8.6 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 1.8 GO:0001076 transcription factor activity, RNA polymerase II transcription factor binding(GO:0001076)
0.0 0.3 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 7.5 GO:0003682 chromatin binding(GO:0003682)
0.0 0.1 GO:0035586 purinergic receptor activity(GO:0035586)
0.0 2.4 GO:0051015 actin filament binding(GO:0051015)
0.0 0.8 GO:0000049 tRNA binding(GO:0000049)
0.0 2.2 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.5 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 1.5 GO:0005549 odorant binding(GO:0005549)
0.0 0.0 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.4 GO:0097602 cullin family protein binding(GO:0097602)
0.0 9.1 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 1.1 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.3 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.1 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.5 GO:0003720 telomerase activity(GO:0003720)
0.0 3.7 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.5 GO:0005158 insulin receptor binding(GO:0005158)
0.0 1.2 GO:0005179 hormone activity(GO:0005179)
0.0 0.2 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.1 GO:0071723 lipopeptide binding(GO:0071723)
0.0 0.2 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229) intracellular chloride channel activity(GO:0061778)
0.0 3.4 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.1 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 2.1 GO:0005088 Ras guanyl-nucleotide exchange factor activity(GO:0005088)
0.0 0.1 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.2 GO:0070717 poly-purine tract binding(GO:0070717)
0.0 0.1 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.2 GO:0003796 lysozyme activity(GO:0003796)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 11.2 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.5 25.5 PID_ATR_PATHWAY ATR signaling pathway
0.5 50.1 PID_P73PATHWAY p73 transcription factor network
0.5 10.9 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.4 11.2 PID_CONE_PATHWAY Visual signal transduction: Cones
0.4 15.8 PID_AURORA_A_PATHWAY Aurora A signaling
0.3 2.1 SA_FAS_SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.3 14.3 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.3 9.5 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.3 6.5 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.3 7.5 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.2 12.2 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.2 11.0 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.2 5.1 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.2 5.8 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.2 4.9 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.2 6.8 PID_AURORA_B_PATHWAY Aurora B signaling
0.2 5.7 PID_AR_NONGENOMIC_PATHWAY Nongenotropic Androgen signaling
0.2 8.0 ST_GA13_PATHWAY G alpha 13 Pathway
0.2 1.7 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 6.2 PID_BMP_PATHWAY BMP receptor signaling
0.1 4.1 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.1 4.4 PID_IL3_PATHWAY IL3-mediated signaling events
0.1 11.4 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 10.4 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.1 5.5 PID_E2F_PATHWAY E2F transcription factor network
0.1 1.2 PID_EPHA2_FWD_PATHWAY EPHA2 forward signaling
0.1 3.3 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 5.6 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 8.9 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.1 3.2 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.1 5.1 PID_RAC1_PATHWAY RAC1 signaling pathway
0.1 1.6 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.1 0.7 PID_ANTHRAX_PATHWAY Cellular roles of Anthrax toxin
0.1 2.3 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.1 5.7 PID_P53_REGULATION_PATHWAY p53 pathway
0.1 2.2 PID_PI3K_PLC_TRK_PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.1 21.0 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 4.2 PID_FGF_PATHWAY FGF signaling pathway
0.1 1.8 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.1 1.3 PID_ERBB1_RECEPTOR_PROXIMAL_PATHWAY EGF receptor (ErbB1) signaling pathway
0.1 1.4 PID_ERBB2_ERBB3_PATHWAY ErbB2/ErbB3 signaling events
0.1 2.6 PID_RAS_PATHWAY Regulation of Ras family activation
0.1 2.8 ST_INTEGRIN_SIGNALING_PATHWAY Integrin Signaling Pathway
0.1 5.5 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.1 0.7 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 0.3 ST_INTERFERON_GAMMA_PATHWAY Interferon gamma pathway.
0.1 1.9 PID_PI3KCI_PATHWAY Class I PI3K signaling events
0.1 0.8 ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY PI3K Pathway
0.1 0.5 PID_CXCR3_PATHWAY CXCR3-mediated signaling events
0.0 0.3 PID_NFKAPPAB_CANONICAL_PATHWAY Canonical NF-kappaB pathway
0.0 1.2 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.0 1.5 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.0 0.2 PID_ALK2_PATHWAY ALK2 signaling events
0.0 2.0 PID_LKB1_PATHWAY LKB1 signaling events
0.0 1.2 PID_TNF_PATHWAY TNF receptor signaling pathway
0.0 1.4 PID_IL12_2PATHWAY IL12-mediated signaling events
0.0 7.8 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 0.8 PID_KIT_PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.4 PID_FCER1_PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.3 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.8 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.0 0.9 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.0 0.5 PID_CD8_TCR_PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.4 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.2 PID_CD8_TCR_DOWNSTREAM_PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.4 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 0.8 PID_CMYB_PATHWAY C-MYB transcription factor network
0.0 2.4 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 18.4 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
1.0 15.8 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.9 5.3 REACTOME_E2F_ENABLED_INHIBITION_OF_PRE_REPLICATION_COMPLEX_FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.8 39.3 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.8 17.7 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.6 12.8 REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.6 13.7 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.6 17.8 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.6 12.5 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
0.5 9.0 REACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX Genes involved in Activation of the pre-replicative complex
0.5 5.6 REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.5 48.4 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.4 1.7 REACTOME_REPAIR_SYNTHESIS_FOR_GAP_FILLING_BY_DNA_POL_IN_TC_NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.4 11.4 REACTOME_KINESINS Genes involved in Kinesins
0.4 21.5 REACTOME_GLUCOSE_TRANSPORT Genes involved in Glucose transport
0.4 16.6 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.4 3.7 REACTOME_G1_S_SPECIFIC_TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.4 9.9 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.4 2.5 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.3 17.6 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.3 8.4 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.3 33.7 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.3 5.7 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.3 2.6 REACTOME_EXTENSION_OF_TELOMERES Genes involved in Extension of Telomeres
0.3 3.4 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.3 5.3 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.3 5.5 REACTOME_ACYL_CHAIN_REMODELLING_OF_PI Genes involved in Acyl chain remodelling of PI
0.3 7.3 REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.2 3.7 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.2 1.8 REACTOME_HORMONE_LIGAND_BINDING_RECEPTORS Genes involved in Hormone ligand-binding receptors
0.2 9.2 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.2 5.0 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.2 10.1 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.2 1.9 REACTOME_PLATELET_SENSITIZATION_BY_LDL Genes involved in Platelet sensitization by LDL
0.2 9.0 REACTOME_INTERFERON_GAMMA_SIGNALING Genes involved in Interferon gamma signaling
0.2 3.3 REACTOME_KERATAN_SULFATE_BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.2 0.9 REACTOME_ADENYLATE_CYCLASE_INHIBITORY_PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.2 3.1 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.2 2.6 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 13.5 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 7.0 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 4.8 REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE Genes involved in GPVI-mediated activation cascade
0.1 3.2 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 6.2 REACTOME_MRNA_SPLICING_MINOR_PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.1 2.9 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_ACTIVATES_SMADS Genes involved in TGF-beta receptor signaling activates SMADs
0.1 1.7 REACTOME_PHOSPHORYLATION_OF_THE_APC_C Genes involved in Phosphorylation of the APC/C
0.1 10.0 REACTOME_MRNA_SPLICING Genes involved in mRNA Splicing
0.1 2.1 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.1 1.0 REACTOME_SIGNALING_BY_CONSTITUTIVELY_ACTIVE_EGFR Genes involved in Signaling by constitutively active EGFR
0.1 8.6 REACTOME_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL Genes involved in Cell surface interactions at the vascular wall
0.1 3.8 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.1 1.9 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.1 1.8 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 1.5 REACTOME_PYRUVATE_METABOLISM Genes involved in Pyruvate metabolism
0.1 2.8 REACTOME_G1_PHASE Genes involved in G1 Phase
0.1 1.0 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 0.8 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade
0.1 1.2 REACTOME_RNA_POL_III_CHAIN_ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.1 4.9 REACTOME_ANTIGEN_PROCESSING_CROSS_PRESENTATION Genes involved in Antigen processing-Cross presentation
0.1 5.0 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 2.7 REACTOME_AMYLOIDS Genes involved in Amyloids
0.1 5.4 REACTOME_SIGNALING_BY_EGFR_IN_CANCER Genes involved in Signaling by EGFR in Cancer
0.1 2.7 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.1 4.2 REACTOME_GLUCOSE_METABOLISM Genes involved in Glucose metabolism
0.0 2.4 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.6 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.7 REACTOME_METABOLISM_OF_NON_CODING_RNA Genes involved in Metabolism of non-coding RNA
0.0 1.1 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.8 REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 8.5 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 2.0 REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.3 REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE_ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.4 REACTOME_ELONGATION_ARREST_AND_RECOVERY Genes involved in Elongation arrest and recovery
0.0 1.4 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.0 5.4 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.6 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 0.6 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 1.1 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.4 REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.6 REACTOME_ACTIVATED_TAK1_MEDIATES_P38_MAPK_ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.6 REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 1.0 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 1.8 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 2.1 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 1.0 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 1.7 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.7 REACTOME_STEROID_HORMONES Genes involved in Steroid hormones
0.0 2.3 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.3 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.5 REACTOME_FRS2_MEDIATED_CASCADE Genes involved in FRS2-mediated cascade
0.0 0.1 REACTOME_TRAF6_MEDIATED_INDUCTION_OF_TAK1_COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex