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GSE58827: Dynamics of the Mouse Liver

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Results for Pitx3

Z-value: 1.28

Motif logo

Transcription factors associated with Pitx3

Gene Symbol Gene ID Gene Info
ENSMUSG00000025229.9 paired-like homeodomain transcription factor 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Pitx3mm10_v2_chr19_-_46148369_461483860.363.3e-02Click!

Activity profile of Pitx3 motif

Sorted Z-values of Pitx3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_181051232 8.08 ENSMUST00000036819.6
RIKEN cDNA 9130409I23 gene
chr9_+_119357381 7.02 ENSMUST00000039610.8
xylulokinase homolog (H. influenzae)
chr8_-_72212837 6.67 ENSMUST00000098630.3
calcium and integrin binding family member 3
chr8_+_114133557 6.48 ENSMUST00000073521.5
ENSMUST00000066514.6
nudix (nucleoside diphosphate linked moiety X)-type motif 7
chr17_-_12675833 6.36 ENSMUST00000024596.8
solute carrier family 22 (organic cation transporter), member 1
chr8_+_114133601 6.27 ENSMUST00000109109.1
nudix (nucleoside diphosphate linked moiety X)-type motif 7
chr15_+_9335550 6.20 ENSMUST00000072403.6
UDP glycosyltransferases 3 family, polypeptide A2
chr8_+_114133635 6.17 ENSMUST00000147605.1
ENSMUST00000134593.1
nudix (nucleoside diphosphate linked moiety X)-type motif 7
chr7_+_26835305 5.54 ENSMUST00000005685.8
cytochrome P450, family 2, subfamily a, polypeptide 5
chr10_+_88459569 5.52 ENSMUST00000020252.3
ENSMUST00000125612.1
synaptonemal complex protein 3
chr13_-_12464925 5.47 ENSMUST00000124888.1
lectin, galactose binding, soluble 8
chr12_-_104044431 5.22 ENSMUST00000043915.3
serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12
chr2_-_24048857 5.07 ENSMUST00000114497.1
histamine N-methyltransferase
chr8_+_127447669 4.97 ENSMUST00000159511.1
par-3 (partitioning defective 3) homolog (C. elegans)
chr8_+_70083509 4.88 ENSMUST00000007738.9
hyaluronan and proteoglycan link protein 4
chr7_-_48843663 4.88 ENSMUST00000167786.2
cysteine and glycine-rich protein 3
chr7_-_100662414 4.72 ENSMUST00000079176.6
pleckstrin homology domain containing, family B (evectins) member 1
chr7_-_100662315 4.61 ENSMUST00000151123.1
ENSMUST00000107047.2
pleckstrin homology domain containing, family B (evectins) member 1
chr6_+_71493850 4.52 ENSMUST00000064637.4
ENSMUST00000114178.1
ring finger protein 103
chrX_+_59999436 4.45 ENSMUST00000033477.4
coagulation factor IX
chrX_+_142226765 4.38 ENSMUST00000112916.2
nuclear transport factor 2-like export factor 2
chr8_-_27228581 4.26 ENSMUST00000121838.1
adrenergic receptor, beta 3
chr5_-_65428354 4.17 ENSMUST00000131263.1
UDP-glucose dehydrogenase
chr6_-_85933379 4.17 ENSMUST00000162660.1
N-acetyltransferase 8B
chr11_-_100770926 4.10 ENSMUST00000139341.1
ENSMUST00000017891.7
GH3 domain containing
chr7_-_19692596 4.03 ENSMUST00000108451.2
ENSMUST00000045035.4
apolipoprotein C-I
chr10_-_41709297 3.89 ENSMUST00000019955.9
ENSMUST00000099932.3
coiled-coil domain containing 162
chr14_+_66635251 3.77 ENSMUST00000159365.1
ENSMUST00000054661.1
ENSMUST00000159068.1
adrenergic receptor, alpha 1a
chr7_+_119900099 3.74 ENSMUST00000106516.1
LYR motif containing 1
chr17_-_46763576 3.66 ENSMUST00000041012.7
pre T cell antigen receptor alpha
chr10_+_62920630 3.64 ENSMUST00000044977.3
solute carrier family 25 (mitochondrial carrier, Graves disease autoantigen), member 16
chr7_-_68275098 3.55 ENSMUST00000135564.1
predicted gene 16157
chr9_-_54068346 3.32 ENSMUST00000098760.3
tumor necrosis factor, alpha-induced protein 8-like 3
chr8_+_46010596 3.31 ENSMUST00000110381.2
Lrp2 binding protein
chrX_+_140381971 3.29 ENSMUST00000044702.6
FERM and PDZ domain containing 3
chr7_+_27029074 3.20 ENSMUST00000075552.5
cytochrome P450, family 2, subfamily a, polypeptide 12
chr7_-_12998172 3.14 ENSMUST00000120903.1
solute carrier family 27 (fatty acid transporter), member 5
chr9_-_15306116 3.01 ENSMUST00000178977.1
RIKEN cDNA 4931406C07 gene
chr9_+_46269069 2.93 ENSMUST00000034584.3
apolipoprotein A-V
chr7_+_131410601 2.91 ENSMUST00000015829.7
ENSMUST00000117518.1
acyl-Coenzyme A dehydrogenase, short/branched chain
chr7_-_12998140 2.89 ENSMUST00000032539.7
solute carrier family 27 (fatty acid transporter), member 5
chr9_-_103305049 2.89 ENSMUST00000142540.1
RIKEN cDNA 1300017J02 gene
chr7_+_26307190 2.87 ENSMUST00000098657.3
cytochrome P450, family 2, subfamily a, polypeptide 4
chr6_+_90550789 2.81 ENSMUST00000130418.1
ENSMUST00000032175.8
aldehyde dehydrogenase 1 family, member L1
chr8_-_3467617 2.78 ENSMUST00000111081.3
ENSMUST00000118194.1
ENSMUST00000004686.6
peroxisomal biogenesis factor 11 gamma
chrX_+_7909542 2.76 ENSMUST00000086274.2
predicted gene 10490
chr7_+_102225812 2.73 ENSMUST00000142873.1
post-GPI attachment to proteins 2
chr19_+_7494033 2.72 ENSMUST00000170373.1
atlastin GTPase 3
chr12_+_36090379 2.72 ENSMUST00000071825.5
predicted gene 5434
chr11_+_9048575 2.69 ENSMUST00000043285.4
predicted gene 11992
chr8_-_72435043 2.66 ENSMUST00000109974.1
calreticulin 3
chr14_-_25927672 2.64 ENSMUST00000185006.1
transmembrane protein 254a
chr1_+_88070765 2.52 ENSMUST00000073772.4
UDP glucuronosyltransferase 1 family, polypeptide A9
chr11_-_120727226 2.42 ENSMUST00000106148.3
ENSMUST00000026144.4
dicarbonyl L-xylulose reductase
chr11_+_102041509 2.41 ENSMUST00000123895.1
ENSMUST00000017453.5
ENSMUST00000107163.2
ENSMUST00000107164.2
CD300 antigen like family member G
chr1_+_167308649 2.39 ENSMUST00000097473.4
transmembrane and coiled-coil domains 1
chr5_+_120513102 2.38 ENSMUST00000111889.1
solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
chr6_-_72617000 2.36 ENSMUST00000070524.4
trans-golgi network protein
chr18_+_51117754 2.33 ENSMUST00000116639.2
proline rich 16
chr10_+_62920648 2.31 ENSMUST00000144459.1
solute carrier family 25 (mitochondrial carrier, Graves disease autoantigen), member 16
chr9_+_77941274 2.30 ENSMUST00000134072.1
ELOVL family member 5, elongation of long chain fatty acids (yeast)
chr4_-_109202217 2.28 ENSMUST00000160774.1
ENSMUST00000030288.7
ENSMUST00000162787.2
oxysterol binding protein-like 9
chr4_+_155582476 2.28 ENSMUST00000105612.1
NAD kinase
chr6_-_128526703 2.26 ENSMUST00000143664.1
ENSMUST00000112132.1
ENSMUST00000032510.7
pregnancy zone protein
chr1_-_184883218 2.25 ENSMUST00000048308.5
RIKEN cDNA C130074G19 gene
chr16_-_91618986 2.24 ENSMUST00000143058.1
ENSMUST00000049244.8
ENSMUST00000169982.1
ENSMUST00000133731.1
DnaJ (Hsp40) homolog, subfamily C, member 28
chr9_+_114731177 2.22 ENSMUST00000035007.8
CKLF-like MARVEL transmembrane domain containing 6
chr6_+_149582012 2.16 ENSMUST00000144085.2
predicted gene, 21814
chr3_+_95318782 2.15 ENSMUST00000139866.1
ceramide synthase 2
chr7_-_126922887 2.13 ENSMUST00000134134.1
ENSMUST00000119781.1
ENSMUST00000121612.2
transmembrane protein 219
chr15_+_99392882 2.12 ENSMUST00000023749.8
transmembrane BAX inhibitor motif containing 6
chr9_-_73039697 2.11 ENSMUST00000184035.1
ENSMUST00000098566.4
phosphatidylinositol glycan anchor biosynthesis, class B
chr1_-_175979114 2.11 ENSMUST00000104983.1
RIKEN cDNA B020018G12 gene
chr11_-_79296906 2.11 ENSMUST00000068448.2
predicted gene 9964
chr2_-_32704123 2.10 ENSMUST00000127812.1
folylpolyglutamyl synthetase
chr11_+_67025144 2.10 ENSMUST00000079077.5
ENSMUST00000061786.5
transmembrane protein 220
chr10_+_58497918 2.07 ENSMUST00000036576.8
coiled-coil domain containing 138
chr4_-_19922599 2.07 ENSMUST00000029900.5
ATPase, H+ transporting, lysosomal V0 subunit D2
chr14_-_26207041 2.05 ENSMUST00000022418.8
transmembrane protein 254b
chr14_+_26082245 2.05 ENSMUST00000168149.2
ENSMUST00000163305.1
cytoplasmic polyadenylated homeobox 2
cytoplasmic polyadenylated homeobox 3
chr9_-_73039644 2.02 ENSMUST00000184389.1
phosphatidylinositol glycan anchor biosynthesis, class B
chrX_-_162888426 1.99 ENSMUST00000033723.3
synapse associated protein 1
chr9_-_64341145 1.96 ENSMUST00000120760.1
ENSMUST00000168844.2
DIS3 mitotic control homolog (S. cerevisiae)-like
chr7_+_68275970 1.94 ENSMUST00000153805.1
family with sequence similarity 169, member B
chr14_+_26221856 1.90 ENSMUST00000184577.1
cytoplasmic polyadenylated homeobox 3
chr14_+_25942492 1.90 ENSMUST00000184016.1
cytoplasmic polyadenylated homeobox 1
chr11_-_106580594 1.88 ENSMUST00000153870.1
testis expressed gene 2
chr1_+_128244122 1.88 ENSMUST00000027592.3
UBX domain protein 4
chr2_+_163122605 1.87 ENSMUST00000144092.1
predicted gene 11454
chr19_+_43782181 1.85 ENSMUST00000026208.4
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr7_+_25619404 1.84 ENSMUST00000077338.5
ENSMUST00000085953.3
ATP5S-like
chr6_+_56017489 1.84 ENSMUST00000052827.4
protein phosphatase 1, regulatory subunit 17
chr17_-_32189457 1.82 ENSMUST00000087721.3
ENSMUST00000162117.1
epoxide hydrolase 3
chr2_-_132578244 1.82 ENSMUST00000110142.1
glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
chr5_+_92376954 1.82 ENSMUST00000120781.1
ADP-ribosyltransferase 3
chr10_-_68278713 1.81 ENSMUST00000020106.7
AT rich interactive domain 5B (MRF1-like)
chr4_+_141368116 1.79 ENSMUST00000006380.4
family with sequence similarity 131, member C
chr9_-_64341288 1.77 ENSMUST00000068367.7
DIS3 mitotic control homolog (S. cerevisiae)-like
chr13_-_74482943 1.74 ENSMUST00000074369.6
zinc finger protein 825
chr9_-_20815048 1.73 ENSMUST00000004201.7
collagen, type V, alpha 3
chr10_-_20548361 1.71 ENSMUST00000164195.1
phosphodiesterase 7B
chr7_-_7299492 1.71 ENSMUST00000000619.6
chloride channel 4-2
chr10_+_80702649 1.71 ENSMUST00000095426.3
IZUMO family member 4
chr10_+_128499364 1.69 ENSMUST00000180477.1
Riken cDNA A430046D13 gene
chr1_-_59161594 1.66 ENSMUST00000078874.7
ENSMUST00000066374.7
membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)
chr1_-_134361933 1.65 ENSMUST00000049470.4
transmembrane protein 183A
chr13_+_67779754 1.64 ENSMUST00000164936.2
ENSMUST00000181319.1
zinc finger protein 493
chr19_-_37330613 1.64 ENSMUST00000131070.1
insulin degrading enzyme
chr2_+_144594054 1.63 ENSMUST00000136628.1
predicted gene 561
chr10_-_12861735 1.63 ENSMUST00000076817.4
utrophin
chr10_-_20548320 1.63 ENSMUST00000169404.1
phosphodiesterase 7B
chr17_-_32420965 1.62 ENSMUST00000170392.1
peptidoglycan recognition protein 2
chr5_+_30853796 1.61 ENSMUST00000126284.1
microtubule-associated protein, RP/EB family, member 3
chrX_-_166479633 1.60 ENSMUST00000049435.8
RAB9, member RAS oncogene family
chr4_+_41755210 1.60 ENSMUST00000108038.1
ENSMUST00000084695.4
galactose-1-phosphate uridyl transferase
chr8_+_105708270 1.60 ENSMUST00000013302.5
RIKEN cDNA 4933405L10 gene
chr11_-_120617887 1.59 ENSMUST00000106188.3
ENSMUST00000026129.9
phosphate cytidylyltransferase 2, ethanolamine
chr10_-_77089428 1.59 ENSMUST00000156009.1
collagen, type XVIII, alpha 1
chr7_+_97720839 1.58 ENSMUST00000070021.1
predicted gene 9990
chr6_-_85762480 1.57 ENSMUST00000168531.1
camello-like 3
chr8_-_105758570 1.56 ENSMUST00000155038.2
ENSMUST00000013294.9
glucose-fructose oxidoreductase domain containing 2
chr4_-_133529326 1.56 ENSMUST00000163919.1
predicted gene, 17688
chr1_+_185332143 1.55 ENSMUST00000027916.6
ENSMUST00000151769.1
ENSMUST00000110965.1
bisphosphate 3'-nucleotidase 1
chr8_+_36489191 1.55 ENSMUST00000171777.1
RIKEN cDNA 6430573F11 gene
chr15_+_31572179 1.55 ENSMUST00000161088.1
carboxymethylenebutenolidase-like (Pseudomonas)
chr3_-_88455735 1.54 ENSMUST00000029700.5
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr9_+_90054529 1.54 ENSMUST00000143172.1
cathepsin H
chrX_-_36874111 1.54 ENSMUST00000047486.5
RIKEN cDNA C330007P06 gene
chr11_-_40695203 1.53 ENSMUST00000101347.3
methionine adenosyltransferase II, beta
chr4_-_44066960 1.51 ENSMUST00000173234.1
ENSMUST00000173274.1
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
chr18_-_3309858 1.51 ENSMUST00000144496.1
ENSMUST00000154715.1
cAMP responsive element modulator
chr11_-_98775333 1.51 ENSMUST00000064941.6
nuclear receptor subfamily 1, group D, member 1
chr11_-_121388186 1.50 ENSMUST00000106107.2
Rab40b, member RAS oncogene family
chr2_-_132578155 1.50 ENSMUST00000110136.1
ENSMUST00000124107.1
ENSMUST00000060955.5
glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
chr1_-_39651165 1.50 ENSMUST00000053355.4
cellular repressor of E1A-stimulated genes 2
chr17_-_35121990 1.47 ENSMUST00000173915.1
ENSMUST00000172765.2
casein kinase 2, beta polypeptide
chr11_-_60811228 1.47 ENSMUST00000018744.8
serine hydroxymethyltransferase 1 (soluble)
chr11_-_4160286 1.46 ENSMUST00000093381.4
ENSMUST00000101626.2
coiled-coil domain containing 157
chr3_-_153912966 1.45 ENSMUST00000089950.4
RAB geranylgeranyl transferase, b subunit
chr11_-_73324616 1.44 ENSMUST00000021119.2
aspartoacylase
chr11_-_116131073 1.44 ENSMUST00000106440.2
ENSMUST00000067632.3
tripartite motif-containing 65
chr18_-_3309723 1.44 ENSMUST00000136961.1
ENSMUST00000152108.1
cAMP responsive element modulator
chr1_-_36244245 1.43 ENSMUST00000046875.7
UDP-glucose glycoprotein glucosyltransferase 1
chr10_+_80151154 1.43 ENSMUST00000146516.1
ENSMUST00000144526.1
midnolin
chr8_+_70131327 1.43 ENSMUST00000095273.5
nuclear receptor 2C2-associated protein
chr5_+_107830244 1.43 ENSMUST00000072578.6
ubiquitin-conjugating enzyme E2D 2B
chr11_-_96916448 1.41 ENSMUST00000103152.4
CDK5 regulatory subunit associated protein 3
chr7_+_30169861 1.41 ENSMUST00000085668.4
predicted gene 5113
chr5_-_134456702 1.41 ENSMUST00000073161.5
ENSMUST00000171794.2
ENSMUST00000111245.2
ENSMUST00000100654.3
ENSMUST00000167084.2
ENSMUST00000100652.3
ENSMUST00000100650.3
ENSMUST00000074114.5
general transcription factor II I repeat domain-containing 1
chrY_+_818646 1.40 ENSMUST00000115894.1
ubiquitin-activating enzyme, Chr Y
chr5_+_106609098 1.40 ENSMUST00000167618.1
predicted gene, 17304
chr7_-_141475131 1.40 ENSMUST00000043870.8
polymerase (RNA) II (DNA directed) polypeptide L
chr7_-_118584669 1.39 ENSMUST00000044195.4
transmembrane channel-like gene family 7
chr4_-_12087912 1.38 ENSMUST00000050686.3
transmembrane protein 67
chr9_-_108567336 1.37 ENSMUST00000074208.4
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 3
chr19_-_29648355 1.35 ENSMUST00000159692.1
endoplasmic reticulum metallopeptidase 1
chr14_-_20702991 1.34 ENSMUST00000180987.1
RIKEN cDNA 6230400D17 gene
chr1_-_59237093 1.34 ENSMUST00000163058.1
ENSMUST00000027178.6
amyotrophic lateral sclerosis 2 (juvenile)
chr6_-_83656082 1.33 ENSMUST00000014686.2
C-type lectin domain family 4, member f
chrX_+_36874351 1.32 ENSMUST00000016452.7
ubiquitin-conjugating enzyme E2A
chr13_-_41220395 1.32 ENSMUST00000021793.7
elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 2
chr1_-_90967667 1.32 ENSMUST00000131428.1
RAB17, member RAS oncogene family
chr14_+_79397772 1.31 ENSMUST00000022600.2
mitochondrial translational release factor 1
chr8_-_71511762 1.31 ENSMUST00000048452.4
plasmalemma vesicle associated protein
chr7_+_24257644 1.30 ENSMUST00000072713.6
zinc finger protein 108
chr4_-_142015056 1.30 ENSMUST00000105780.1
forkhead-associated (FHA) phosphopeptide binding domain 1
chr11_+_51261719 1.30 ENSMUST00000130641.1
CDC like kinase 4
chr8_+_33653238 1.29 ENSMUST00000033992.8
glutathione reductase
chr11_-_78080360 1.28 ENSMUST00000021183.3
Era (G-protein)-like 1 (E. coli)
chr7_+_6252710 1.27 ENSMUST00000121024.1
predicted gene 6792
chr7_+_19489045 1.27 ENSMUST00000011407.7
ENSMUST00000137613.1
exocyst complex component 3-like 2
chr2_+_69670100 1.27 ENSMUST00000100050.3
kelch-like 41
chr5_-_121618865 1.27 ENSMUST00000041252.6
ENSMUST00000111776.1
acyl-Coenzyme A dehydrogenase family, member 12
chr5_+_117976761 1.27 ENSMUST00000035579.6
F-box protein 21
chr10_-_43540945 1.26 ENSMUST00000147196.1
ENSMUST00000019932.3
RIKEN cDNA 1700021F05 gene
chr2_+_140152043 1.26 ENSMUST00000104994.2
predicted gene, 17374
chr10_+_39612934 1.26 ENSMUST00000019987.6
TRAF3 interacting protein 2
chr11_+_22971991 1.26 ENSMUST00000049506.5
zinc finger (CCCH type), RNA binding motif and serine/arginine rich 1
chr8_+_71951038 1.25 ENSMUST00000131237.1
ENSMUST00000136516.1
ENSMUST00000109997.2
ENSMUST00000132848.1
zinc finger protein 961
chr17_+_46711459 1.25 ENSMUST00000002840.8
peroxisomal biogenesis factor 6
chr9_-_62070606 1.24 ENSMUST00000034785.7
glucuronyl C5-epimerase
chr3_-_88455692 1.24 ENSMUST00000107531.1
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr2_-_25236787 1.24 ENSMUST00000091318.4
predicted gene 757
chr11_-_29247208 1.23 ENSMUST00000020754.3
coiled-coil domain containing 104
chr8_-_72213636 1.23 ENSMUST00000109987.1
predicted gene 11034
chr2_-_121380940 1.22 ENSMUST00000038389.8
stereocilin
chr11_+_101448403 1.21 ENSMUST00000010502.6
interferon-induced protein 35
chr15_+_76701455 1.21 ENSMUST00000019224.7
major facilitator superfamily domain containing 3
chr10_+_61417972 1.20 ENSMUST00000049339.6
nodal
chr8_+_47824459 1.20 ENSMUST00000038693.6
claudin 22
chr9_+_22454290 1.19 ENSMUST00000168332.1
predicted gene, 17545
chr6_+_114643106 1.19 ENSMUST00000169310.3
ENSMUST00000182169.1
ENSMUST00000183165.1
ENSMUST00000182098.1
ENSMUST00000182793.1
ENSMUST00000182902.1
ENSMUST00000182428.1
ENSMUST00000182035.1
autophagy related 7
chr7_-_144738520 1.19 ENSMUST00000118556.2
ENSMUST00000033393.8
anoctamin 1, calcium activated chloride channel
chr2_-_132578128 1.19 ENSMUST00000028822.7
glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
chr2_+_158502633 1.19 ENSMUST00000109484.1
adipogenin
chr1_+_171225054 1.18 ENSMUST00000111321.1
ENSMUST00000005824.5
ENSMUST00000111320.1
ENSMUST00000111319.1
apolipoprotein A-II
chr11_+_97029925 1.18 ENSMUST00000021249.4
secernin 2
chr1_-_5070281 1.17 ENSMUST00000147158.1
ENSMUST00000118000.1
regulator of G-protein signaling 20
chr17_+_94873986 1.17 ENSMUST00000108007.4
predicted gene, 20939
chr3_-_88334428 1.17 ENSMUST00000107552.1
transmembrane protein 79

Network of associatons between targets according to the STRING database.

First level regulatory network of Pitx3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.7 18.9 GO:0034031 coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034) acetyl-CoA catabolic process(GO:0046356)
3.1 9.4 GO:0042732 D-xylose metabolic process(GO:0042732)
1.6 4.9 GO:1903919 regulation of actin filament severing(GO:1903918) negative regulation of actin filament severing(GO:1903919)
1.5 6.0 GO:0046951 ketone body biosynthetic process(GO:0046951)
1.5 5.8 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
1.4 5.5 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
1.3 3.8 GO:0001983 baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
1.1 4.3 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
1.0 4.1 GO:0010901 regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
1.0 5.1 GO:0001692 histamine metabolic process(GO:0001692)
0.9 2.8 GO:0042560 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.9 5.5 GO:0002317 plasma cell differentiation(GO:0002317)
0.8 5.0 GO:0003383 apical constriction(GO:0003383)
0.7 3.7 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.7 2.2 GO:0034727 lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) suppression by virus of host autophagy(GO:0039521) negative regulation of sphingolipid biosynthesis involved in cellular sphingolipid homeostasis(GO:0090157)
0.7 2.1 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.7 2.0 GO:0042335 cuticle development(GO:0042335)
0.7 2.0 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.5 2.1 GO:1903976 peripheral nervous system axon regeneration(GO:0014012) negative regulation of glial cell migration(GO:1903976)
0.5 1.6 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.5 1.0 GO:0010899 regulation of phosphatidylcholine catabolic process(GO:0010899)
0.5 0.5 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.5 14.4 GO:0080184 response to phenylpropanoid(GO:0080184)
0.5 1.4 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.5 2.8 GO:0044375 regulation of peroxisome size(GO:0044375)
0.5 1.8 GO:0050787 detoxification of mercury ion(GO:0050787)
0.5 2.3 GO:0006741 NADP biosynthetic process(GO:0006741)
0.4 1.3 GO:0042275 error-free postreplication DNA repair(GO:0042275)
0.4 2.1 GO:0031438 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.4 1.2 GO:0030210 heparin biosynthetic process(GO:0030210)
0.4 1.6 GO:0007525 somatic muscle development(GO:0007525)
0.4 1.6 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.4 5.2 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.4 1.2 GO:0048320 axial mesoderm formation(GO:0048320)
0.4 1.5 GO:0010813 neuropeptide catabolic process(GO:0010813) dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.4 1.5 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.4 1.5 GO:0006231 dTMP biosynthetic process(GO:0006231) dTMP metabolic process(GO:0046073)
0.4 1.4 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.4 1.1 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.3 1.4 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.3 1.0 GO:1901856 negative regulation of cellular respiration(GO:1901856)
0.3 1.6 GO:0010815 bradykinin catabolic process(GO:0010815)
0.3 1.6 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253) negative regulation of natural killer cell differentiation(GO:0032824) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
0.3 4.5 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.3 3.5 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.3 3.6 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.3 1.5 GO:0070859 positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.3 1.4 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.3 1.1 GO:1900110 negative regulation of histone H3-K9 dimethylation(GO:1900110)
0.3 0.8 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.3 1.1 GO:0006166 purine ribonucleoside salvage(GO:0006166)
0.3 4.1 GO:0097502 mannosylation(GO:0097502)
0.3 0.8 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.3 0.8 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.2 2.2 GO:0033227 dsRNA transport(GO:0033227)
0.2 1.2 GO:1903772 regulation of viral budding via host ESCRT complex(GO:1903772)
0.2 1.4 GO:0006083 acetate metabolic process(GO:0006083)
0.2 0.7 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.2 1.9 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.2 0.7 GO:0046340 transcription initiation from RNA polymerase I promoter(GO:0006361) diacylglycerol catabolic process(GO:0046340)
0.2 0.7 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.2 1.6 GO:0052428 modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.2 1.8 GO:0060613 fat pad development(GO:0060613)
0.2 3.1 GO:0070244 negative regulation of thymocyte apoptotic process(GO:0070244)
0.2 2.2 GO:0015705 iodide transport(GO:0015705)
0.2 1.1 GO:0060295 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108) regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.2 0.6 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.2 1.5 GO:0000237 leptotene(GO:0000237)
0.2 2.5 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.2 0.6 GO:1905223 epicardium morphogenesis(GO:1905223)
0.2 2.2 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.2 0.6 GO:1990167 protein K6-linked deubiquitination(GO:0044313) protein K27-linked deubiquitination(GO:1990167)
0.2 2.4 GO:0006983 ER overload response(GO:0006983)
0.2 0.8 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.2 0.8 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.2 0.8 GO:0030043 actin filament fragmentation(GO:0030043)
0.2 1.0 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.2 1.2 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.2 3.2 GO:0006895 Golgi to endosome transport(GO:0006895)
0.2 0.6 GO:0045645 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.2 1.7 GO:0018344 protein geranylgeranylation(GO:0018344)
0.2 0.6 GO:0006667 sphinganine metabolic process(GO:0006667)
0.2 1.1 GO:0051204 protein insertion into mitochondrial membrane(GO:0051204)
0.2 1.3 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.2 0.7 GO:0046294 formaldehyde catabolic process(GO:0046294)
0.2 0.7 GO:0009816 defense response to bacterium, incompatible interaction(GO:0009816) regulation of defense response to bacterium, incompatible interaction(GO:1902477)
0.2 1.4 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.2 0.5 GO:0010512 negative regulation of phosphatidylinositol biosynthetic process(GO:0010512)
0.2 1.3 GO:0009249 protein lipoylation(GO:0009249)
0.2 0.3 GO:0071898 regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
0.2 0.6 GO:0051790 threonine metabolic process(GO:0006566) short-chain fatty acid biosynthetic process(GO:0051790)
0.2 0.8 GO:0009446 putrescine biosynthetic process(GO:0009446)
0.2 2.4 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.2 1.4 GO:0071569 protein ufmylation(GO:0071569)
0.2 0.6 GO:0072362 regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362)
0.1 0.6 GO:0006788 heme oxidation(GO:0006788)
0.1 0.9 GO:0072092 ureteric bud invasion(GO:0072092)
0.1 0.7 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.1 0.6 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.1 0.7 GO:0015817 histidine transport(GO:0015817)
0.1 0.4 GO:0008594 photoreceptor cell morphogenesis(GO:0008594)
0.1 0.6 GO:1902044 regulation of Fas signaling pathway(GO:1902044) negative regulation of Fas signaling pathway(GO:1902045)
0.1 1.4 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.1 0.8 GO:0032466 negative regulation of cytokinesis(GO:0032466)
0.1 0.9 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.1 0.9 GO:0032790 ribosome disassembly(GO:0032790)
0.1 0.8 GO:0046490 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate metabolic process(GO:0046490)
0.1 1.2 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.1 0.6 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.1 GO:0000915 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.1 0.5 GO:1902093 positive regulation of sperm motility(GO:1902093)
0.1 0.1 GO:0060854 patterning of lymph vessels(GO:0060854)
0.1 0.5 GO:0045872 regulation of rhodopsin gene expression(GO:0007468) positive regulation of rhodopsin gene expression(GO:0045872)
0.1 0.7 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.1 1.6 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.1 1.0 GO:0051026 chiasma assembly(GO:0051026)
0.1 1.1 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 3.5 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.1 3.4 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.1 0.6 GO:2001166 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.1 0.5 GO:0034769 basement membrane disassembly(GO:0034769)
0.1 1.1 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.1 3.2 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.1 0.7 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1 0.6 GO:0001980 regulation of systemic arterial blood pressure by ischemic conditions(GO:0001980)
0.1 0.3 GO:0046462 monoacylglycerol metabolic process(GO:0046462)
0.1 1.5 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.1 1.2 GO:0006228 UTP biosynthetic process(GO:0006228)
0.1 0.9 GO:0097475 motor neuron migration(GO:0097475)
0.1 1.3 GO:0051132 NK T cell activation(GO:0051132)
0.1 4.2 GO:0001702 gastrulation with mouth forming second(GO:0001702)
0.1 0.6 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.1 3.1 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.1 0.6 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.1 1.0 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.1 1.4 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.1 2.5 GO:0045793 positive regulation of cell size(GO:0045793)
0.1 0.6 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.3 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.1 1.3 GO:0031272 regulation of pseudopodium assembly(GO:0031272)
0.1 0.9 GO:0033683 nucleotide-excision repair, DNA incision(GO:0033683)
0.1 2.1 GO:0007035 vacuolar acidification(GO:0007035)
0.1 6.6 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.1 0.3 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.1 0.9 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500) protein localization to photoreceptor outer segment(GO:1903546)
0.1 0.3 GO:0046882 negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.1 0.2 GO:0033686 positive regulation of luteinizing hormone secretion(GO:0033686)
0.1 0.9 GO:0097033 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1 1.5 GO:0006047 UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.1 0.2 GO:0070949 regulation of neutrophil mediated cytotoxicity(GO:0070948) regulation of neutrophil mediated killing of symbiont cell(GO:0070949)
0.1 0.7 GO:0071763 nuclear membrane organization(GO:0071763)
0.1 1.3 GO:0051601 exocyst localization(GO:0051601)
0.1 1.6 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.1 0.3 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.1 0.6 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.1 2.7 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.1 0.8 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.1 0.2 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726)
0.1 1.3 GO:0006415 translational termination(GO:0006415)
0.1 0.8 GO:0051255 spindle midzone assembly(GO:0051255)
0.1 0.5 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
0.1 0.5 GO:2000002 negative regulation of macrophage differentiation(GO:0045650) negative regulation of DNA damage checkpoint(GO:2000002)
0.1 0.9 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.1 0.4 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 0.4 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.1 1.2 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.1 0.5 GO:0044838 cell quiescence(GO:0044838)
0.1 4.1 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.1 0.7 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.1 0.3 GO:0002636 positive regulation of germinal center formation(GO:0002636)
0.1 1.0 GO:0021940 positive regulation of cerebellar granule cell precursor proliferation(GO:0021940)
0.1 1.3 GO:0001783 B cell apoptotic process(GO:0001783)
0.1 0.5 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.1 1.8 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 0.7 GO:0045591 positive regulation of regulatory T cell differentiation(GO:0045591)
0.1 0.4 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
0.1 0.8 GO:0002051 osteoblast fate commitment(GO:0002051)
0.1 0.6 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.1 1.3 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1 1.2 GO:0050872 white fat cell differentiation(GO:0050872)
0.1 0.8 GO:0021702 cerebellar Purkinje cell differentiation(GO:0021702)
0.1 0.4 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.1 0.4 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.1 0.1 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.1 1.5 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.5 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
0.0 2.7 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.2 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 1.1 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 1.8 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.5 GO:0031282 regulation of guanylate cyclase activity(GO:0031282)
0.0 0.7 GO:0042407 cristae formation(GO:0042407)
0.0 0.7 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.0 1.6 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.6 GO:0034067 protein localization to Golgi apparatus(GO:0034067)
0.0 5.0 GO:0008203 cholesterol metabolic process(GO:0008203)
0.0 0.9 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.5 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.4 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.5 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.0 0.6 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0 1.3 GO:0033522 histone H2A ubiquitination(GO:0033522)
0.0 0.4 GO:0070475 rRNA base methylation(GO:0070475)
0.0 1.3 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 1.1 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.2 GO:1901836 regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901836)
0.0 1.8 GO:0019835 cytolysis(GO:0019835)
0.0 0.2 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.2 GO:1900103 positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103)
0.0 0.6 GO:0035404 histone-serine phosphorylation(GO:0035404)
0.0 2.9 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 0.1 GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0 1.4 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.4 GO:1902916 positive regulation of protein polyubiquitination(GO:1902916)
0.0 1.1 GO:0097286 iron ion import(GO:0097286)
0.0 0.2 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.0 2.0 GO:0001541 ovarian follicle development(GO:0001541)
0.0 3.6 GO:0031638 zymogen activation(GO:0031638)
0.0 0.6 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.0 1.3 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.4 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.3 GO:1902416 positive regulation of mRNA binding(GO:1902416)
0.0 1.3 GO:0007032 endosome organization(GO:0007032)
0.0 0.5 GO:0006458 'de novo' protein folding(GO:0006458)
0.0 0.9 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.1 GO:0036015 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.0 0.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.2 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.0 1.1 GO:0008089 anterograde axonal transport(GO:0008089)
0.0 0.4 GO:0003094 glomerular filtration(GO:0003094)
0.0 0.8 GO:0021904 dorsal/ventral neural tube patterning(GO:0021904)
0.0 0.4 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 2.7 GO:0051028 mRNA transport(GO:0051028)
0.0 0.8 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.2 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.8 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.9 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 0.6 GO:0006379 mRNA cleavage(GO:0006379)
0.0 0.9 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 0.1 GO:0070676 intralumenal vesicle formation(GO:0070676) negative regulation of early endosome to late endosome transport(GO:2000642)
0.0 0.1 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.0 0.4 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 1.4 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.4 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 1.1 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.0 GO:0071726 response to diacyl bacterial lipopeptide(GO:0071724) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to diacyl bacterial lipopeptide(GO:0071726) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.0 0.7 GO:0019236 response to pheromone(GO:0019236)
0.0 0.1 GO:0032988 ribonucleoprotein complex disassembly(GO:0032988)
0.0 0.4 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.5 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.4 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 1.7 GO:0035418 protein localization to synapse(GO:0035418)
0.0 4.2 GO:0006839 mitochondrial transport(GO:0006839)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.8 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.7 GO:0006953 acute-phase response(GO:0006953)
0.0 4.6 GO:0000398 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0 0.9 GO:0009154 purine ribonucleotide catabolic process(GO:0009154) ribonucleotide catabolic process(GO:0009261)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.4 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 0.1 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.2 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.2 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504) antigen processing and presentation of peptide antigen(GO:0048002)
0.0 0.8 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.1 GO:0070933 histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933)
0.0 0.3 GO:0043574 protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 0.0 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 5.0 GO:0033269 internode region of axon(GO:0033269)
0.6 1.7 GO:0005588 collagen type V trimer(GO:0005588)
0.6 2.3 GO:0097447 dendritic tree(GO:0097447)
0.5 1.5 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.4 1.3 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.4 1.6 GO:0000802 transverse filament(GO:0000802)
0.3 1.4 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.3 3.7 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.3 1.1 GO:1902636 kinociliary basal body(GO:1902636)
0.3 1.9 GO:0033503 HULC complex(GO:0033503)
0.3 6.8 GO:0034385 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.2 0.9 GO:0005745 m-AAA complex(GO:0005745)
0.2 1.1 GO:1990130 Iml1 complex(GO:1990130)
0.2 1.5 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.2 2.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.2 0.8 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.2 2.8 GO:0017119 Golgi transport complex(GO:0017119)
0.2 0.6 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
0.2 2.5 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.2 0.9 GO:1990923 PET complex(GO:1990923)
0.2 1.1 GO:0097255 R2TP complex(GO:0097255)
0.2 2.1 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.1 0.6 GO:0035339 SPOTS complex(GO:0035339)
0.1 1.8 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 1.3 GO:0089701 U2AF(GO:0089701)
0.1 0.8 GO:0032133 chromosome passenger complex(GO:0032133)
0.1 2.4 GO:0030061 mitochondrial crista(GO:0030061)
0.1 1.7 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.1 0.4 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.1 1.5 GO:0097208 alveolar lamellar body(GO:0097208)
0.1 1.1 GO:0000813 ESCRT I complex(GO:0000813)
0.1 0.9 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.1 2.6 GO:0031527 filopodium membrane(GO:0031527)
0.1 2.7 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 0.4 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.1 2.9 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 0.8 GO:0070187 telosome(GO:0070187)
0.1 10.0 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 0.6 GO:1990584 cardiac Troponin complex(GO:1990584)
0.1 0.4 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.1 22.6 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 0.9 GO:0000243 commitment complex(GO:0000243)
0.1 7.8 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 1.4 GO:0036038 MKS complex(GO:0036038)
0.1 0.6 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.1 0.5 GO:0000439 core TFIIH complex(GO:0000439)
0.1 13.0 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 1.4 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 0.7 GO:0061617 MICOS complex(GO:0061617)
0.1 0.5 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 0.7 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.1 2.4 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.1 1.7 GO:0005684 U2-type spliceosomal complex(GO:0005684)
0.1 0.1 GO:0071010 prespliceosome(GO:0071010)
0.1 2.2 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.1 2.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 0.6 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 2.7 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 1.1 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.1 1.3 GO:0000145 exocyst(GO:0000145)
0.1 1.3 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 1.0 GO:0031528 microvillus membrane(GO:0031528)
0.0 9.3 GO:0030018 Z disc(GO:0030018)
0.0 1.9 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 1.0 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.1 GO:0000814 ESCRT II complex(GO:0000814)
0.0 0.8 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.9 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.5 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.5 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.1 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.0 0.1 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 5.1 GO:0030496 midbody(GO:0030496)
0.0 2.2 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.4 GO:0032009 early phagosome(GO:0032009)
0.0 0.9 GO:0045095 keratin filament(GO:0045095)
0.0 0.1 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.0 0.4 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.6 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.3 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.1 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 11.4 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 0.2 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.1 GO:0070469 respiratory chain(GO:0070469)
0.0 0.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.6 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 1.4 GO:0005882 intermediate filament(GO:0005882)
0.0 0.6 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 2.0 GO:0005581 collagen trimer(GO:0005581)
0.0 1.7 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.2 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 1.4 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.3 GO:0030008 TRAPP complex(GO:0030008)
0.0 1.5 GO:0030667 secretory granule membrane(GO:0030667)
0.0 4.9 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 1.2 GO:0005811 lipid particle(GO:0005811)
0.0 0.1 GO:0042588 zymogen granule(GO:0042588)
0.0 0.5 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.9 GO:0005844 polysome(GO:0005844)
0.0 1.2 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.0 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 0.4 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.1 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.0 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.8 18.9 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
2.1 6.4 GO:0005333 norepinephrine transmembrane transporter activity(GO:0005333)
2.0 8.1 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
1.4 4.2 GO:0003979 UDP-glucose 6-dehydrogenase activity(GO:0003979)
1.1 4.5 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
1.1 4.3 GO:0031699 beta-adrenergic receptor activity(GO:0004939) beta-3 adrenergic receptor binding(GO:0031699)
0.9 3.8 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.9 2.8 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.8 4.9 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.7 2.2 GO:0019778 Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779)
0.7 2.1 GO:0070905 serine binding(GO:0070905)
0.6 2.4 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
0.5 4.1 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.5 1.4 GO:0019807 aspartoacylase activity(GO:0019807)
0.5 6.0 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.5 1.4 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
0.4 1.6 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441)
0.4 1.5 GO:0030984 kininogen binding(GO:0030984)
0.4 2.2 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.4 2.2 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.4 1.4 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.4 2.1 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.4 1.1 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.3 2.8 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.3 1.6 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745) peptidoglycan receptor activity(GO:0016019)
0.3 11.6 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.3 1.5 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761)
0.3 3.6 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.3 1.2 GO:0070698 type I activin receptor binding(GO:0070698)
0.3 1.9 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.3 0.3 GO:0004661 protein geranylgeranyltransferase activity(GO:0004661)
0.3 1.6 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.3 2.8 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.3 1.3 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.3 1.0 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.3 2.3 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.3 0.8 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.2 2.7 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.2 0.7 GO:0018738 S-formylglutathione hydrolase activity(GO:0018738)
0.2 0.7 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.2 0.7 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.2 8.8 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.2 1.8 GO:0043559 insulin binding(GO:0043559)
0.2 2.1 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.2 4.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 1.1 GO:0070287 ferritin receptor activity(GO:0070287)
0.2 1.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.2 0.8 GO:0003998 acylphosphatase activity(GO:0003998)
0.2 0.8 GO:0004452 isopentenyl-diphosphate delta-isomerase activity(GO:0004452)
0.2 1.3 GO:0005534 galactose binding(GO:0005534)
0.2 4.2 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.2 1.4 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.2 4.1 GO:0000030 mannosyltransferase activity(GO:0000030)
0.2 1.3 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.2 1.3 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.2 2.4 GO:0019865 immunoglobulin binding(GO:0019865)
0.1 0.6 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 0.7 GO:0005290 L-histidine transmembrane transporter activity(GO:0005290)
0.1 1.6 GO:0070569 uridylyltransferase activity(GO:0070569)
0.1 1.6 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.1 1.4 GO:0001055 RNA polymerase II activity(GO:0001055)
0.1 0.6 GO:0035877 death effector domain binding(GO:0035877)
0.1 0.4 GO:0008988 rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) U6 snRNA 3'-end binding(GO:0030629)
0.1 1.1 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.1 1.8 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1 4.3 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.1 1.0 GO:0043199 sulfate binding(GO:0043199)
0.1 0.4 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.1 4.3 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 1.9 GO:0001164 RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.1 0.6 GO:0089720 caspase binding(GO:0089720)
0.1 4.4 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.1 0.7 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 0.6 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 2.6 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 2.3 GO:0003951 NAD+ kinase activity(GO:0003951)
0.1 1.9 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 1.6 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 1.2 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1 0.6 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.1 1.3 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.1 0.6 GO:0030172 troponin C binding(GO:0030172)
0.1 3.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 0.5 GO:0030250 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.1 0.6 GO:0001595 angiotensin receptor activity(GO:0001595)
0.1 0.3 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.1 1.6 GO:0017166 vinculin binding(GO:0017166)
0.1 4.4 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 1.5 GO:0035174 histone serine kinase activity(GO:0035174)
0.1 1.5 GO:0016805 dipeptidase activity(GO:0016805)
0.1 0.3 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.1 0.6 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.1 0.5 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.1 1.2 GO:0070411 I-SMAD binding(GO:0070411)
0.1 1.5 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 0.3 GO:0016842 amidine-lyase activity(GO:0016842)
0.1 1.0 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.4 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.1 1.4 GO:0051787 misfolded protein binding(GO:0051787)
0.1 1.4 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.1 1.2 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1 5.4 GO:0008170 N-methyltransferase activity(GO:0008170)
0.1 2.4 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor(GO:0016655)
0.1 1.8 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.1 0.3 GO:0001032 RNA polymerase III type 3 promoter DNA binding(GO:0001032)
0.1 1.8 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.3 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 1.0 GO:0035497 cAMP response element binding(GO:0035497)
0.0 1.5 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.9 GO:0042166 acetylcholine binding(GO:0042166)
0.0 1.8 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.3 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.6 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 0.8 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.4 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.1 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0 0.8 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.4 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.9 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 2.9 GO:0019003 GDP binding(GO:0019003)
0.0 0.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.4 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 1.1 GO:0070064 proline-rich region binding(GO:0070064)
0.0 4.7 GO:0005178 integrin binding(GO:0005178)
0.0 0.1 GO:0004915 interleukin-6 receptor activity(GO:0004915) leukemia inhibitory factor receptor activity(GO:0004923) interleukin-6 binding(GO:0019981)
0.0 0.1 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0 0.6 GO:0005123 death receptor binding(GO:0005123)
0.0 0.5 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.4 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.5 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.6 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.0 1.2 GO:0015295 solute:proton symporter activity(GO:0015295)
0.0 0.3 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.3 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.9 GO:0030145 manganese ion binding(GO:0030145)
0.0 1.9 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.4 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.6 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 1.2 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.1 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.0 0.8 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 1.1 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.0 0.1 GO:0052795 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.5 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.4 GO:0035325 Toll-like receptor binding(GO:0035325)
0.0 0.7 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 0.9 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.9 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.1 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 5.7 GO:0000287 magnesium ion binding(GO:0000287)
0.0 7.3 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 0.9 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.4 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.8 GO:0005112 Notch binding(GO:0005112)
0.0 0.6 GO:0017069 snRNA binding(GO:0017069)
0.0 0.9 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.8 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.1 GO:0098918 structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.0 0.3 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 2.5 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.7 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.0 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.0 1.8 GO:0008565 protein transporter activity(GO:0008565)
0.0 1.1 GO:0038024 cargo receptor activity(GO:0038024)
0.0 2.5 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.0 4.7 GO:0003924 GTPase activity(GO:0003924)
0.0 0.1 GO:0051766 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0 2.6 GO:0005506 iron ion binding(GO:0005506)
0.0 0.8 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.4 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.3 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 2.7 GO:0005125 cytokine activity(GO:0005125)
0.0 1.5 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.4 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.2 GO:0016918 retinal binding(GO:0016918) retinol binding(GO:0019841)
0.0 0.2 GO:0043855 cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 1.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.7 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.5 GO:0005109 frizzled binding(GO:0005109)
0.0 0.3 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.7 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.2 GO:0042287 MHC protein binding(GO:0042287)
0.0 0.3 GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.2 1.6 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 1.4 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 5.1 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 2.9 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 2.7 PID ALK1 PATHWAY ALK1 signaling events
0.1 3.3 NABA COLLAGENS Genes encoding collagen proteins
0.1 0.6 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 4.4 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.8 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 5.0 PID NOTCH PATHWAY Notch signaling pathway
0.0 1.3 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.6 PID IL5 PATHWAY IL5-mediated signaling events
0.0 1.2 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 2.2 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.4 PID AURORA B PATHWAY Aurora B signaling
0.0 0.4 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.6 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.8 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 0.7 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 3.4 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.7 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.6 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.4 PID P73PATHWAY p73 transcription factor network
0.0 0.9 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.9 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 6.0 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.5 6.7 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.5 6.4 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.4 5.9 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.3 4.4 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.2 8.0 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.2 4.8 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.2 3.6 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.2 4.1 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.2 0.5 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 3.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 2.9 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 1.4 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 1.6 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 2.8 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 5.2 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 1.0 REACTOME LIPOPROTEIN METABOLISM Genes involved in Lipoprotein metabolism
0.1 0.9 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 2.6 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 1.6 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 1.4 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 1.9 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 1.9 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.1 1.6 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.1 0.9 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 1.2 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.1 2.7 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 3.1 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.1 1.7 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.6 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 3.2 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 1.3 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.8 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.4 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.6 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 0.7 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.8 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 1.7 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.5 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.8 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.6 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.9 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 1.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.7 REACTOME PRE NOTCH EXPRESSION AND PROCESSING Genes involved in Pre-NOTCH Expression and Processing
0.0 0.3 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.0 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.0 0.5 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 2.0 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 1.1 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.1 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.1 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.7 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis