Motif ID: Pitx3

Z-value: 1.275


Transcription factors associated with Pitx3:

Gene SymbolEntrez IDGene Name
Pitx3 ENSMUSG00000025229.9 Pitx3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pitx3mm10_v2_chr19_-_46148369_461483860.363.3e-02Click!


Activity profile for motif Pitx3.

activity profile for motif Pitx3


Sorted Z-values histogram for motif Pitx3

Sorted Z-values for motif Pitx3



Network of associatons between targets according to the STRING database.



First level regulatory network of Pitx3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_181051232 8.079 ENSMUST00000036819.6
9130409I23Rik
RIKEN cDNA 9130409I23 gene
chr9_+_119357381 7.022 ENSMUST00000039610.8
Xylb
xylulokinase homolog (H. influenzae)
chr8_-_72212837 6.667 ENSMUST00000098630.3
Cib3
calcium and integrin binding family member 3
chr8_+_114133557 6.483 ENSMUST00000073521.5
ENSMUST00000066514.6
Nudt7

nudix (nucleoside diphosphate linked moiety X)-type motif 7

chr17_-_12675833 6.357 ENSMUST00000024596.8
Slc22a1
solute carrier family 22 (organic cation transporter), member 1
chr8_+_114133601 6.267 ENSMUST00000109109.1
Nudt7
nudix (nucleoside diphosphate linked moiety X)-type motif 7
chr15_+_9335550 6.200 ENSMUST00000072403.6
Ugt3a2
UDP glycosyltransferases 3 family, polypeptide A2
chr8_+_114133635 6.169 ENSMUST00000147605.1
ENSMUST00000134593.1
Nudt7

nudix (nucleoside diphosphate linked moiety X)-type motif 7

chr7_+_26835305 5.537 ENSMUST00000005685.8
Cyp2a5
cytochrome P450, family 2, subfamily a, polypeptide 5
chr10_+_88459569 5.517 ENSMUST00000020252.3
ENSMUST00000125612.1
Sycp3

synaptonemal complex protein 3

chr13_-_12464925 5.472 ENSMUST00000124888.1
Lgals8
lectin, galactose binding, soluble 8
chr12_-_104044431 5.223 ENSMUST00000043915.3
Serpina12
serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12
chr2_-_24048857 5.065 ENSMUST00000114497.1
Hnmt
histamine N-methyltransferase
chr8_+_127447669 4.972 ENSMUST00000159511.1
Pard3
par-3 (partitioning defective 3) homolog (C. elegans)
chr8_+_70083509 4.884 ENSMUST00000007738.9
Hapln4
hyaluronan and proteoglycan link protein 4
chr7_-_48843663 4.878 ENSMUST00000167786.2
Csrp3
cysteine and glycine-rich protein 3
chr7_-_100662414 4.719 ENSMUST00000079176.6
Plekhb1
pleckstrin homology domain containing, family B (evectins) member 1
chr7_-_100662315 4.614 ENSMUST00000151123.1
ENSMUST00000107047.2
Plekhb1

pleckstrin homology domain containing, family B (evectins) member 1

chr6_+_71493850 4.524 ENSMUST00000064637.4
ENSMUST00000114178.1
Rnf103

ring finger protein 103

chrX_+_59999436 4.445 ENSMUST00000033477.4
F9
coagulation factor IX
chrX_+_142226765 4.380 ENSMUST00000112916.2
Nxt2
nuclear transport factor 2-like export factor 2
chr8_-_27228581 4.256 ENSMUST00000121838.1
Adrb3
adrenergic receptor, beta 3
chr5_-_65428354 4.168 ENSMUST00000131263.1
Ugdh
UDP-glucose dehydrogenase
chr6_-_85933379 4.165 ENSMUST00000162660.1
Nat8b
N-acetyltransferase 8B
chr11_-_100770926 4.096 ENSMUST00000139341.1
ENSMUST00000017891.7
Ghdc

GH3 domain containing

chr7_-_19692596 4.033 ENSMUST00000108451.2
ENSMUST00000045035.4
Apoc1

apolipoprotein C-I

chr10_-_41709297 3.890 ENSMUST00000019955.9
ENSMUST00000099932.3
Ccdc162

coiled-coil domain containing 162

chr14_+_66635251 3.767 ENSMUST00000159365.1
ENSMUST00000054661.1
ENSMUST00000159068.1
Adra1a


adrenergic receptor, alpha 1a


chr7_+_119900099 3.738 ENSMUST00000106516.1
Lyrm1
LYR motif containing 1
chr17_-_46763576 3.657 ENSMUST00000041012.7
Ptcra
pre T cell antigen receptor alpha
chr10_+_62920630 3.636 ENSMUST00000044977.3
Slc25a16
solute carrier family 25 (mitochondrial carrier, Graves disease autoantigen), member 16
chr7_-_68275098 3.547 ENSMUST00000135564.1
Gm16157
predicted gene 16157
chr9_-_54068346 3.324 ENSMUST00000098760.3
Tnfaip8l3
tumor necrosis factor, alpha-induced protein 8-like 3
chr8_+_46010596 3.306 ENSMUST00000110381.2
Lrp2bp
Lrp2 binding protein
chrX_+_140381971 3.294 ENSMUST00000044702.6
Frmpd3
FERM and PDZ domain containing 3
chr7_+_27029074 3.203 ENSMUST00000075552.5
Cyp2a12
cytochrome P450, family 2, subfamily a, polypeptide 12
chr7_-_12998172 3.145 ENSMUST00000120903.1
Slc27a5
solute carrier family 27 (fatty acid transporter), member 5
chr9_-_15306116 3.011 ENSMUST00000178977.1
4931406C07Rik
RIKEN cDNA 4931406C07 gene
chr9_+_46269069 2.928 ENSMUST00000034584.3
Apoa5
apolipoprotein A-V
chr7_+_131410601 2.912 ENSMUST00000015829.7
ENSMUST00000117518.1
Acadsb

acyl-Coenzyme A dehydrogenase, short/branched chain

chr7_-_12998140 2.895 ENSMUST00000032539.7
Slc27a5
solute carrier family 27 (fatty acid transporter), member 5
chr9_-_103305049 2.894 ENSMUST00000142540.1
1300017J02Rik
RIKEN cDNA 1300017J02 gene
chr7_+_26307190 2.869 ENSMUST00000098657.3
Cyp2a4
cytochrome P450, family 2, subfamily a, polypeptide 4
chr6_+_90550789 2.813 ENSMUST00000130418.1
ENSMUST00000032175.8
Aldh1l1

aldehyde dehydrogenase 1 family, member L1

chr8_-_3467617 2.779 ENSMUST00000111081.3
ENSMUST00000118194.1
ENSMUST00000004686.6
Pex11g


peroxisomal biogenesis factor 11 gamma


chrX_+_7909542 2.756 ENSMUST00000086274.2
Gm10490
predicted gene 10490
chr7_+_102225812 2.727 ENSMUST00000142873.1
Pgap2
post-GPI attachment to proteins 2
chr19_+_7494033 2.724 ENSMUST00000170373.1
Atl3
atlastin GTPase 3
chr12_+_36090379 2.721 ENSMUST00000071825.5
Gm5434
predicted gene 5434
chr11_+_9048575 2.693 ENSMUST00000043285.4
Gm11992
predicted gene 11992
chr8_-_72435043 2.658 ENSMUST00000109974.1
Calr3
calreticulin 3
chr14_-_25927672 2.644 ENSMUST00000185006.1
Tmem254a
transmembrane protein 254a
chr1_+_88070765 2.516 ENSMUST00000073772.4
Ugt1a9
UDP glucuronosyltransferase 1 family, polypeptide A9
chr11_-_120727226 2.422 ENSMUST00000106148.3
ENSMUST00000026144.4
Dcxr

dicarbonyl L-xylulose reductase

chr11_+_102041509 2.414 ENSMUST00000123895.1
ENSMUST00000017453.5
ENSMUST00000107163.2
ENSMUST00000107164.2
Cd300lg



CD300 antigen like family member G



chr1_+_167308649 2.390 ENSMUST00000097473.4
Tmco1
transmembrane and coiled-coil domains 1
chr5_+_120513102 2.384 ENSMUST00000111889.1
Slc8b1
solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
chr6_-_72617000 2.361 ENSMUST00000070524.4
Tgoln1
trans-golgi network protein
chr18_+_51117754 2.330 ENSMUST00000116639.2
Prr16
proline rich 16
chr10_+_62920648 2.312 ENSMUST00000144459.1
Slc25a16
solute carrier family 25 (mitochondrial carrier, Graves disease autoantigen), member 16
chr9_+_77941274 2.303 ENSMUST00000134072.1
Elovl5
ELOVL family member 5, elongation of long chain fatty acids (yeast)
chr4_-_109202217 2.283 ENSMUST00000160774.1
ENSMUST00000030288.7
ENSMUST00000162787.2
Osbpl9


oxysterol binding protein-like 9


chr4_+_155582476 2.276 ENSMUST00000105612.1
Nadk
NAD kinase
chr6_-_128526703 2.263 ENSMUST00000143664.1
ENSMUST00000112132.1
ENSMUST00000032510.7
Pzp


pregnancy zone protein


chr1_-_184883218 2.245 ENSMUST00000048308.5
C130074G19Rik
RIKEN cDNA C130074G19 gene
chr16_-_91618986 2.239 ENSMUST00000143058.1
ENSMUST00000049244.8
ENSMUST00000169982.1
ENSMUST00000133731.1
Dnajc28



DnaJ (Hsp40) homolog, subfamily C, member 28



chr9_+_114731177 2.224 ENSMUST00000035007.8
Cmtm6
CKLF-like MARVEL transmembrane domain containing 6
chr6_+_149582012 2.164 ENSMUST00000144085.2
Gm21814
predicted gene, 21814
chr3_+_95318782 2.146 ENSMUST00000139866.1
Cers2
ceramide synthase 2
chr7_-_126922887 2.131 ENSMUST00000134134.1
ENSMUST00000119781.1
ENSMUST00000121612.2
Tmem219


transmembrane protein 219


chr15_+_99392882 2.123 ENSMUST00000023749.8
Tmbim6
transmembrane BAX inhibitor motif containing 6
chr9_-_73039697 2.112 ENSMUST00000184035.1
ENSMUST00000098566.4
Pigb

phosphatidylinositol glycan anchor biosynthesis, class B

chr1_-_175979114 2.111 ENSMUST00000104983.1
B020018G12Rik
RIKEN cDNA B020018G12 gene
chr11_-_79296906 2.105 ENSMUST00000068448.2
Gm9964
predicted gene 9964
chr2_-_32704123 2.104 ENSMUST00000127812.1
Fpgs
folylpolyglutamyl synthetase
chr11_+_67025144 2.103 ENSMUST00000079077.5
ENSMUST00000061786.5
Tmem220

transmembrane protein 220

chr10_+_58497918 2.072 ENSMUST00000036576.8
Ccdc138
coiled-coil domain containing 138
chr4_-_19922599 2.068 ENSMUST00000029900.5
Atp6v0d2
ATPase, H+ transporting, lysosomal V0 subunit D2
chr14_-_26207041 2.046 ENSMUST00000022418.8
Tmem254b
transmembrane protein 254b
chr14_+_26082245 2.046 ENSMUST00000163305.1
ENSMUST00000168149.2
Cphx3
Cphx2
cytoplasmic polyadenylated homeobox 3
cytoplasmic polyadenylated homeobox 2
chr9_-_73039644 2.023 ENSMUST00000184389.1
Pigb
phosphatidylinositol glycan anchor biosynthesis, class B
chrX_-_162888426 1.995 ENSMUST00000033723.3
Syap1
synapse associated protein 1
chr9_-_64341145 1.963 ENSMUST00000120760.1
ENSMUST00000168844.2
Dis3l

DIS3 mitotic control homolog (S. cerevisiae)-like

chr7_+_68275970 1.938 ENSMUST00000153805.1
Fam169b
family with sequence similarity 169, member B
chr14_+_26221856 1.897 ENSMUST00000184577.1
Cphx3
cytoplasmic polyadenylated homeobox 3
chr14_+_25942492 1.896 ENSMUST00000184016.1
Cphx1
cytoplasmic polyadenylated homeobox 1
chr11_-_106580594 1.884 ENSMUST00000153870.1
Tex2
testis expressed gene 2
chr1_+_128244122 1.875 ENSMUST00000027592.3
Ubxn4
UBX domain protein 4
chr2_+_163122605 1.870 ENSMUST00000144092.1
Gm11454
predicted gene 11454
chr19_+_43782181 1.846 ENSMUST00000026208.4
Abcc2
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr7_+_25619404 1.840 ENSMUST00000077338.5
ENSMUST00000085953.3
Atp5sl

ATP5S-like

chr6_+_56017489 1.839 ENSMUST00000052827.4
Ppp1r17
protein phosphatase 1, regulatory subunit 17
chr17_-_32189457 1.825 ENSMUST00000087721.3
ENSMUST00000162117.1
Ephx3

epoxide hydrolase 3

chr2_-_132578244 1.822 ENSMUST00000110142.1
Gpcpd1
glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
chr5_+_92376954 1.815 ENSMUST00000120781.1
Art3
ADP-ribosyltransferase 3
chr10_-_68278713 1.812 ENSMUST00000020106.7
Arid5b
AT rich interactive domain 5B (MRF1-like)
chr4_+_141368116 1.794 ENSMUST00000006380.4
Fam131c
family with sequence similarity 131, member C
chr9_-_64341288 1.770 ENSMUST00000068367.7
Dis3l
DIS3 mitotic control homolog (S. cerevisiae)-like
chr13_-_74482943 1.744 ENSMUST00000074369.6
Zfp825
zinc finger protein 825
chr9_-_20815048 1.734 ENSMUST00000004201.7
Col5a3
collagen, type V, alpha 3
chr10_-_20548361 1.713 ENSMUST00000164195.1
Pde7b
phosphodiesterase 7B
chr7_-_7299492 1.710 ENSMUST00000000619.6
Clcn4-2
chloride channel 4-2
chr10_+_80702649 1.709 ENSMUST00000095426.3
Izumo4
IZUMO family member 4
chr10_+_128499364 1.693 ENSMUST00000180477.1
A430046D13Rik
Riken cDNA A430046D13 gene
chr1_-_59161594 1.661 ENSMUST00000078874.7
ENSMUST00000066374.7
Mpp4

membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)

chr1_-_134361933 1.646 ENSMUST00000049470.4
Tmem183a
transmembrane protein 183A
chr13_+_67779754 1.643 ENSMUST00000164936.2
ENSMUST00000181319.1
Zfp493

zinc finger protein 493

chr19_-_37330613 1.641 ENSMUST00000131070.1
Ide
insulin degrading enzyme
chr2_+_144594054 1.634 ENSMUST00000136628.1
Gm561
predicted gene 561
chr10_-_12861735 1.633 ENSMUST00000076817.4
Utrn
utrophin
chr10_-_20548320 1.626 ENSMUST00000169404.1
Pde7b
phosphodiesterase 7B
chr17_-_32420965 1.623 ENSMUST00000170392.1
Pglyrp2
peptidoglycan recognition protein 2
chr5_+_30853796 1.609 ENSMUST00000126284.1
Mapre3
microtubule-associated protein, RP/EB family, member 3
chrX_-_166479633 1.601 ENSMUST00000049435.8
Rab9
RAB9, member RAS oncogene family
chr4_+_41755210 1.597 ENSMUST00000108038.1
ENSMUST00000084695.4
Galt

galactose-1-phosphate uridyl transferase

chr8_+_105708270 1.596 ENSMUST00000013302.5
4933405L10Rik
RIKEN cDNA 4933405L10 gene
chr11_-_120617887 1.588 ENSMUST00000106188.3
ENSMUST00000026129.9
Pcyt2

phosphate cytidylyltransferase 2, ethanolamine

chr10_-_77089428 1.588 ENSMUST00000156009.1
Col18a1
collagen, type XVIII, alpha 1
chr7_+_97720839 1.576 ENSMUST00000070021.1
Gm9990
predicted gene 9990
chr6_-_85762480 1.572 ENSMUST00000168531.1
Cml3
camello-like 3
chr8_-_105758570 1.565 ENSMUST00000155038.2
ENSMUST00000013294.9
Gfod2

glucose-fructose oxidoreductase domain containing 2

chr4_-_133529326 1.561 ENSMUST00000163919.1
Gm17688
predicted gene, 17688
chr1_+_185332143 1.553 ENSMUST00000027916.6
ENSMUST00000151769.1
ENSMUST00000110965.1
Bpnt1


bisphosphate 3'-nucleotidase 1


chr8_+_36489191 1.552 ENSMUST00000171777.1
6430573F11Rik
RIKEN cDNA 6430573F11 gene
chr15_+_31572179 1.549 ENSMUST00000161088.1
Cmbl
carboxymethylenebutenolidase-like (Pseudomonas)
chr3_-_88455735 1.544 ENSMUST00000029700.5
Sema4a
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr9_+_90054529 1.543 ENSMUST00000143172.1
Ctsh
cathepsin H
chrX_-_36874111 1.540 ENSMUST00000047486.5
C330007P06Rik
RIKEN cDNA C330007P06 gene
chr11_-_40695203 1.528 ENSMUST00000101347.3
Mat2b
methionine adenosyltransferase II, beta
chr4_-_44066960 1.513 ENSMUST00000173234.1
ENSMUST00000173274.1
Gne

glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase

chr18_-_3309858 1.510 ENSMUST00000144496.1
ENSMUST00000154715.1
Crem

cAMP responsive element modulator

chr11_-_98775333 1.509 ENSMUST00000064941.6
Nr1d1
nuclear receptor subfamily 1, group D, member 1
chr11_-_121388186 1.500 ENSMUST00000106107.2
Rab40b
Rab40b, member RAS oncogene family
chr2_-_132578155 1.498 ENSMUST00000110136.1
ENSMUST00000124107.1
ENSMUST00000060955.5
Gpcpd1


glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)


chr1_-_39651165 1.495 ENSMUST00000053355.4
Creg2
cellular repressor of E1A-stimulated genes 2
chr17_-_35121990 1.473 ENSMUST00000173915.1
ENSMUST00000172765.2
Csnk2b

casein kinase 2, beta polypeptide

chr11_-_60811228 1.465 ENSMUST00000018744.8
Shmt1
serine hydroxymethyltransferase 1 (soluble)
chr11_-_4160286 1.458 ENSMUST00000093381.4
ENSMUST00000101626.2
Ccdc157

coiled-coil domain containing 157

chr3_-_153912966 1.448 ENSMUST00000089950.4
Rabggtb
RAB geranylgeranyl transferase, b subunit
chr11_-_73324616 1.442 ENSMUST00000021119.2
Aspa
aspartoacylase
chr11_-_116131073 1.440 ENSMUST00000106440.2
ENSMUST00000067632.3
Trim65

tripartite motif-containing 65

chr18_-_3309723 1.437 ENSMUST00000136961.1
ENSMUST00000152108.1
Crem

cAMP responsive element modulator

chr1_-_36244245 1.434 ENSMUST00000046875.7
Uggt1
UDP-glucose glycoprotein glucosyltransferase 1
chr10_+_80151154 1.430 ENSMUST00000146516.1
ENSMUST00000144526.1
Midn

midnolin

chr8_+_70131327 1.427 ENSMUST00000095273.5
Nr2c2ap
nuclear receptor 2C2-associated protein
chr5_+_107830244 1.426 ENSMUST00000072578.6
Ube2d2b
ubiquitin-conjugating enzyme E2D 2B
chr11_-_96916448 1.414 ENSMUST00000103152.4
Cdk5rap3
CDK5 regulatory subunit associated protein 3
chr7_+_30169861 1.413 ENSMUST00000085668.4
Gm5113
predicted gene 5113
chr5_-_134456702 1.406 ENSMUST00000073161.5
ENSMUST00000171794.2
ENSMUST00000111245.2
ENSMUST00000100654.3
ENSMUST00000167084.2
ENSMUST00000100652.3
ENSMUST00000100650.3
ENSMUST00000074114.5
Gtf2ird1







general transcription factor II I repeat domain-containing 1







chrY_+_818646 1.405 ENSMUST00000115894.1
Uba1y
ubiquitin-activating enzyme, Chr Y
chr5_+_106609098 1.402 ENSMUST00000167618.1
Gm17304
predicted gene, 17304
chr7_-_141475131 1.397 ENSMUST00000043870.8
Polr2l
polymerase (RNA) II (DNA directed) polypeptide L
chr7_-_118584669 1.385 ENSMUST00000044195.4
Tmc7
transmembrane channel-like gene family 7
chr4_-_12087912 1.377 ENSMUST00000050686.3
Tmem67
transmembrane protein 67
chr9_-_108567336 1.374 ENSMUST00000074208.4
Ndufaf3
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 3
chr19_-_29648355 1.346 ENSMUST00000159692.1
Ermp1
endoplasmic reticulum metallopeptidase 1
chr14_-_20702991 1.343 ENSMUST00000180987.1
6230400D17Rik
RIKEN cDNA 6230400D17 gene
chr1_-_59237093 1.341 ENSMUST00000163058.1
ENSMUST00000027178.6
Als2

amyotrophic lateral sclerosis 2 (juvenile)

chr6_-_83656082 1.335 ENSMUST00000014686.2
Clec4f
C-type lectin domain family 4, member f
chrX_+_36874351 1.323 ENSMUST00000016452.7
Ube2a
ubiquitin-conjugating enzyme E2A
chr13_-_41220395 1.321 ENSMUST00000021793.7
Elovl2
elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 2
chr1_-_90967667 1.316 ENSMUST00000131428.1
Rab17
RAB17, member RAS oncogene family
chr14_+_79397772 1.306 ENSMUST00000022600.2
Mtrf1
mitochondrial translational release factor 1
chr8_-_71511762 1.306 ENSMUST00000048452.4
Plvap
plasmalemma vesicle associated protein
chr7_+_24257644 1.303 ENSMUST00000072713.6
Zfp108
zinc finger protein 108
chr4_-_142015056 1.302 ENSMUST00000105780.1
Fhad1
forkhead-associated (FHA) phosphopeptide binding domain 1
chr11_+_51261719 1.296 ENSMUST00000130641.1
Clk4
CDC like kinase 4
chr8_+_33653238 1.289 ENSMUST00000033992.8
Gsr
glutathione reductase
chr11_-_78080360 1.280 ENSMUST00000021183.3
Eral1
Era (G-protein)-like 1 (E. coli)
chr7_+_6252710 1.273 ENSMUST00000121024.1
Gm6792
predicted gene 6792
chr7_+_19489045 1.273 ENSMUST00000011407.7
ENSMUST00000137613.1
Exoc3l2

exocyst complex component 3-like 2

chr2_+_69670100 1.272 ENSMUST00000100050.3
Klhl41
kelch-like 41
chr5_-_121618865 1.271 ENSMUST00000041252.6
ENSMUST00000111776.1
Acad12

acyl-Coenzyme A dehydrogenase family, member 12

chr5_+_117976761 1.269 ENSMUST00000035579.6
Fbxo21
F-box protein 21
chr10_-_43540945 1.263 ENSMUST00000147196.1
ENSMUST00000019932.3
1700021F05Rik

RIKEN cDNA 1700021F05 gene

chr2_+_140152043 1.262 ENSMUST00000104994.2
Gm17374
predicted gene, 17374
chr10_+_39612934 1.259 ENSMUST00000019987.6
Traf3ip2
TRAF3 interacting protein 2
chr11_+_22971991 1.258 ENSMUST00000049506.5
Zrsr1
zinc finger (CCCH type), RNA binding motif and serine/arginine rich 1
chr8_+_71951038 1.253 ENSMUST00000131237.1
ENSMUST00000136516.1
ENSMUST00000109997.2
ENSMUST00000132848.1
Zfp961



zinc finger protein 961



chr17_+_46711459 1.249 ENSMUST00000002840.8
Pex6
peroxisomal biogenesis factor 6
chr9_-_62070606 1.244 ENSMUST00000034785.7
Glce
glucuronyl C5-epimerase
chr3_-_88455692 1.243 ENSMUST00000107531.1
Sema4a
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr2_-_25236787 1.236 ENSMUST00000091318.4
Gm757
predicted gene 757
chr11_-_29247208 1.230 ENSMUST00000020754.3
Ccdc104
coiled-coil domain containing 104
chr8_-_72213636 1.228 ENSMUST00000109987.1
Gm11034
predicted gene 11034
chr2_-_121380940 1.216 ENSMUST00000038389.8
Strc
stereocilin
chr11_+_101448403 1.213 ENSMUST00000010502.6
Ifi35
interferon-induced protein 35
chr15_+_76701455 1.210 ENSMUST00000019224.7
Mfsd3
major facilitator superfamily domain containing 3
chr10_+_61417972 1.202 ENSMUST00000049339.6
Nodal
nodal
chr8_+_47824459 1.196 ENSMUST00000038693.6
Cldn22
claudin 22
chr9_+_22454290 1.193 ENSMUST00000168332.1
Gm17545
predicted gene, 17545
chr6_+_114643106 1.190 ENSMUST00000169310.3
ENSMUST00000182169.1
ENSMUST00000183165.1
ENSMUST00000182098.1
ENSMUST00000182793.1
ENSMUST00000182902.1
ENSMUST00000182428.1
ENSMUST00000182035.1
Atg7







autophagy related 7







chr7_-_144738520 1.186 ENSMUST00000118556.2
ENSMUST00000033393.8
Ano1

anoctamin 1, calcium activated chloride channel

chr2_-_132578128 1.186 ENSMUST00000028822.7
Gpcpd1
glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
chr2_+_158502633 1.186 ENSMUST00000109484.1
Adig
adipogenin
chr1_+_171225054 1.185 ENSMUST00000111321.1
ENSMUST00000005824.5
ENSMUST00000111320.1
ENSMUST00000111319.1
Apoa2



apolipoprotein A-II



chr11_+_97029925 1.182 ENSMUST00000021249.4
Scrn2
secernin 2
chr1_-_5070281 1.175 ENSMUST00000147158.1
ENSMUST00000118000.1
Rgs20

regulator of G-protein signaling 20

chr17_+_94873986 1.175 ENSMUST00000108007.4
Gm20939
predicted gene, 20939
chr3_-_88334428 1.173 ENSMUST00000107552.1
Tmem79
transmembrane protein 79

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
6.3 18.9 GO:0015938 coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034)
3.1 9.4 GO:0042732 D-xylose metabolic process(GO:0042732)
1.6 4.9 GO:1903918 regulation of actin filament severing(GO:1903918) negative regulation of actin filament severing(GO:1903919)
1.5 6.0 GO:0046951 ketone body biosynthetic process(GO:0046951)
1.4 5.5 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
1.3 3.8 GO:0001983 baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
1.1 4.3 GO:0002025 norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure(GO:0002025)
1.0 4.1 GO:0010901 regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
1.0 5.1 GO:0001692 histamine metabolic process(GO:0001692)
0.9 2.8 GO:0042560 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.9 5.5 GO:0002317 plasma cell differentiation(GO:0002317)
0.8 5.0 GO:0003383 apical constriction(GO:0003383)
0.7 3.7 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.7 2.2 GO:0016237 lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) suppression by virus of host autophagy(GO:0039521) negative regulation of sphingolipid biosynthesis involved in cellular sphingolipid homeostasis(GO:0090157) nucleus disassembly(GO:1905690)
0.7 6.4 GO:1901374 acetate ester transport(GO:1901374)
0.7 2.1 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.7 2.0 GO:0042335 cuticle development(GO:0042335)
0.7 2.0 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.6 3.0 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.6 2.4 GO:0099093 mitochondrial calcium release(GO:0099093)
0.5 2.1 GO:0014012 peripheral nervous system axon regeneration(GO:0014012) negative regulation of glial cell migration(GO:1903976)
0.5 1.0 GO:0010899 regulation of phosphatidylcholine catabolic process(GO:0010899)
0.5 0.5 GO:1904152 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) regulation of retrograde protein transport, ER to cytosol(GO:1904152) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.5 1.4 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.5 2.8 GO:0044375 regulation of peroxisome size(GO:0044375)
0.5 1.8 GO:0050787 detoxification of mercury ion(GO:0050787)
0.5 2.3 GO:0006741 NADP biosynthetic process(GO:0006741)
0.4 1.3 GO:0042275 error-free postreplication DNA repair(GO:0042275)
0.4 2.1 GO:1904721 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.4 1.2 GO:0030210 heparin biosynthetic process(GO:0030210)
0.4 1.6 GO:0007525 somatic muscle development(GO:0007525)
0.4 1.6 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.4 1.2 GO:0048320 axial mesoderm formation(GO:0048320)
0.4 1.5 GO:0010813 neuropeptide catabolic process(GO:0010813) dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.4 1.5 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.4 1.5 GO:0046073 dTMP biosynthetic process(GO:0006231) dTMP metabolic process(GO:0046073)
0.4 1.4 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.4 11.6 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.3 5.2 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.3 1.4 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.3 1.0 GO:1901856 negative regulation of cellular respiration(GO:1901856)
0.3 1.6 GO:0010815 bradykinin catabolic process(GO:0010815)
0.3 1.6 GO:0032824 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253) negative regulation of natural killer cell differentiation(GO:0032824) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
0.3 4.5 GO:0072501 cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.3 1.0 GO:0000963 mitochondrial RNA processing(GO:0000963)
0.3 3.6 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.3 1.5 GO:0070859 positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.3 1.2 GO:0032324 molybdopterin cofactor biosynthetic process(GO:0032324)
0.3 1.4 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.3 1.1 GO:1900110 negative regulation of histone H3-K9 dimethylation(GO:1900110)
0.3 0.8 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.3 1.1 GO:0006166 purine ribonucleoside salvage(GO:0006166)
0.3 0.8 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.3 0.8 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.2 2.2 GO:0033227 dsRNA transport(GO:0033227)
0.2 1.2 GO:1903772 regulation of viral budding via host ESCRT complex(GO:1903772)
0.2 1.4 GO:0006083 acetate metabolic process(GO:0006083)
0.2 0.7 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.2 1.9 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.2 0.7 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.2 0.7 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361) diacylglycerol catabolic process(GO:0046340)
0.2 0.7 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.2 1.6 GO:0044362 negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) negative regulation by host of symbiont molecular function(GO:0052405)
0.2 1.8 GO:0060613 fat pad development(GO:0060613)
0.2 3.1 GO:0070244 negative regulation of thymocyte apoptotic process(GO:0070244)
0.2 1.1 GO:0060295 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108) regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.2 0.6 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.2 1.5 GO:0000237 leptotene(GO:0000237)
0.2 2.5 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.2 0.6 GO:1905223 epicardium morphogenesis(GO:1905223)
0.2 2.2 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.2 0.6 GO:0044313 protein K6-linked deubiquitination(GO:0044313) protein K27-linked deubiquitination(GO:1990167)
0.2 2.2 GO:0015705 iodide transport(GO:0015705)
0.2 2.4 GO:0006983 ER overload response(GO:0006983)
0.2 0.8 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.2 0.8 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.2 0.8 GO:0030043 actin filament fragmentation(GO:0030043)
0.2 1.0 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.2 3.2 GO:0006895 Golgi to endosome transport(GO:0006895)
0.2 0.6 GO:0045645 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.2 1.7 GO:0018344 protein geranylgeranylation(GO:0018344)
0.2 0.6 GO:0006667 sphinganine metabolic process(GO:0006667)
0.2 3.4 GO:0016075 rRNA catabolic process(GO:0016075)
0.2 1.3 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.2 0.7 GO:0046294 formaldehyde catabolic process(GO:0046294)
0.2 0.7 GO:0009816 defense response to bacterium, incompatible interaction(GO:0009816) regulation of defense response to bacterium, incompatible interaction(GO:1902477)
0.2 0.7 GO:0015817 histidine transport(GO:0015817)
0.2 1.4 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.2 0.5 GO:0010512 negative regulation of phosphatidylinositol biosynthetic process(GO:0010512)
0.2 1.3 GO:0009249 protein lipoylation(GO:0009249)
0.2 0.3 GO:0071898 regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
0.2 0.6 GO:0051790 threonine metabolic process(GO:0006566) short-chain fatty acid biosynthetic process(GO:0051790)
0.2 0.8 GO:0009446 putrescine biosynthetic process(GO:0009446)
0.2 1.4 GO:0071569 protein ufmylation(GO:0071569)
0.2 0.9 GO:0032790 ribosome disassembly(GO:0032790)
0.2 0.6 GO:0072362 regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362)
0.1 6.9 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.1 0.6 GO:0006788 heme oxidation(GO:0006788)
0.1 0.9 GO:0072092 ureteric bud invasion(GO:0072092)
0.1 0.7 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.1 0.6 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.1 0.4 GO:0008594 photoreceptor cell morphogenesis(GO:0008594)
0.1 0.6 GO:1902044 regulation of Fas signaling pathway(GO:1902044) negative regulation of Fas signaling pathway(GO:1902045)
0.1 1.4 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.1 0.8 GO:0032466 negative regulation of cytokinesis(GO:0032466)
0.1 0.9 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.1 1.2 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.1 0.6 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.1 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.1 0.5 GO:1902093 positive regulation of flagellated sperm motility(GO:1902093)
0.1 0.1 GO:0060854 branching involved in lymph vessel morphogenesis(GO:0060854)
0.1 0.5 GO:0045872 regulation of rhodopsin gene expression(GO:0007468) positive regulation of rhodopsin gene expression(GO:0045872)
0.1 0.7 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.1 1.6 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.1 1.0 GO:0051026 chiasma assembly(GO:0051026)
0.1 1.1 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 3.4 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.1 3.5 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.1 0.6 GO:2001168 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.1 0.5 GO:0034769 basement membrane disassembly(GO:0034769)
0.1 0.7 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1 0.6 GO:0001980 regulation of systemic arterial blood pressure by ischemic conditions(GO:0001980)
0.1 0.3 GO:0046462 monoacylglycerol metabolic process(GO:0046462)
0.1 1.5 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.1 1.2 GO:0006228 UTP biosynthetic process(GO:0006228)
0.1 0.9 GO:0097475 motor neuron migration(GO:0097475)
0.1 0.4 GO:0040031 snRNA modification(GO:0040031)
0.1 1.3 GO:0051132 NK T cell activation(GO:0051132)
0.1 0.6 GO:0051204 protein insertion into mitochondrial membrane(GO:0051204)
0.1 4.2 GO:0001702 gastrulation with mouth forming second(GO:0001702)
0.1 1.1 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.1 0.6 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.1 3.1 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.1 0.6 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.1 1.0 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.1 0.8 GO:0046490 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate metabolic process(GO:0046490)
0.1 2.5 GO:0045793 positive regulation of cell size(GO:0045793)
0.1 0.6 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.3 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.1 1.3 GO:0031272 regulation of pseudopodium assembly(GO:0031272)
0.1 0.9 GO:0033683 nucleotide-excision repair, DNA incision(GO:0033683)
0.1 2.1 GO:0007035 vacuolar acidification(GO:0007035)
0.1 0.9 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.1 0.3 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.1 0.9 GO:1903546 receptor localization to non-motile cilium(GO:0097500) protein localization to photoreceptor outer segment(GO:1903546)
0.1 0.3 GO:0046882 negative regulation of luteinizing hormone secretion(GO:0033685) negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.1 0.2 GO:0033686 positive regulation of luteinizing hormone secretion(GO:0033686)
0.1 0.9 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1 2.1 GO:1902579 multi-organism transport(GO:0044766) multi-organism localization(GO:1902579)
0.1 1.5 GO:0006047 UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.1 1.6 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.1 0.2 GO:0070948 regulation of neutrophil mediated cytotoxicity(GO:0070948) regulation of neutrophil mediated killing of symbiont cell(GO:0070949)
0.1 5.0 GO:0031638 zymogen activation(GO:0031638)
0.1 1.3 GO:0051601 exocyst localization(GO:0051601)
0.1 0.3 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.1 6.2 GO:1901655 cellular response to ketone(GO:1901655)
0.1 0.8 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.1 6.6 GO:0030433 ubiquitin-dependent ERAD pathway(GO:0030433)
0.1 0.8 GO:0051255 spindle midzone assembly(GO:0051255)
0.1 0.5 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
0.1 0.7 GO:0071763 nuclear membrane organization(GO:0071763)
0.1 0.4 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 0.4 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.1 1.3 GO:0001783 B cell apoptotic process(GO:0001783)
0.1 0.6 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.1 0.5 GO:0044838 cell quiescence(GO:0044838)
0.1 4.1 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.1 0.7 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.1 0.3 GO:0002636 positive regulation of germinal center formation(GO:0002636)
0.1 1.0 GO:0021940 positive regulation of cerebellar granule cell precursor proliferation(GO:0021940)
0.1 0.5 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.1 1.8 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 0.7 GO:0045591 positive regulation of regulatory T cell differentiation(GO:0045591)
0.1 0.4 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
0.1 0.8 GO:0002051 osteoblast fate commitment(GO:0002051)
0.1 1.6 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 0.8 GO:0021702 cerebellar Purkinje cell differentiation(GO:0021702)
0.1 0.6 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.1 1.2 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.1 1.3 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1 5.5 GO:0042157 lipoprotein metabolic process(GO:0042157)
0.1 0.4 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.1 0.4 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.1 1.2 GO:0050872 white fat cell differentiation(GO:0050872)
0.1 1.1 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 2.7 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.1 0.1 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.1 1.3 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.5 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
0.0 1.6 GO:0007566 embryo implantation(GO:0007566)
0.0 0.6 GO:0098664 serotonin receptor signaling pathway(GO:0007210) G-protein coupled serotonin receptor signaling pathway(GO:0098664)
0.0 0.7 GO:0042407 cristae formation(GO:0042407)
0.0 0.6 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.0 1.8 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.7 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.0 0.6 GO:0034067 protein localization to Golgi apparatus(GO:0034067)
0.0 0.9 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.5 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.4 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.5 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.0 1.8 GO:0019835 cytolysis(GO:0019835)
0.0 1.3 GO:0033522 histone H2A ubiquitination(GO:0033522)
0.0 1.3 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.7 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.2 GO:1901838 regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901836) positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0 0.6 GO:0048863 stem cell differentiation(GO:0048863)
0.0 1.1 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.2 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726)
0.0 0.2 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.1 GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0 1.4 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.4 GO:1902916 positive regulation of protein polyubiquitination(GO:1902916)
0.0 1.1 GO:0097286 iron ion import(GO:0097286)
0.0 0.6 GO:0035404 histone-serine phosphorylation(GO:0035404)
0.0 2.9 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 2.0 GO:0001541 ovarian follicle development(GO:0001541)
0.0 0.2 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.0 1.3 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.4 GO:0015866 ADP transport(GO:0015866)
0.0 0.4 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.5 GO:0006458 'de novo' protein folding(GO:0006458)
0.0 0.5 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.9 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 1.4 GO:0007032 endosome organization(GO:0007032)
0.0 0.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 1.7 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.2 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.0 0.3 GO:1902416 positive regulation of mRNA binding(GO:1902416)
0.0 0.9 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 1.1 GO:0008089 anterograde axonal transport(GO:0008089)
0.0 0.8 GO:0021904 dorsal/ventral neural tube patterning(GO:0021904)
0.0 0.4 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.2 GO:0060330 regulation of response to interferon-gamma(GO:0060330)
0.0 0.8 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.2 GO:1904637 interleukin-21 production(GO:0032625) cellular response to ether(GO:0071362) interleukin-21 secretion(GO:0072619) response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.0 0.9 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 1.7 GO:0035418 protein localization to synapse(GO:0035418)
0.0 2.6 GO:0051028 mRNA transport(GO:0051028)
0.0 0.1 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.0 1.0 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.6 GO:0006379 mRNA cleavage(GO:0006379)
0.0 0.4 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 1.1 GO:0140053 mitochondrial gene expression(GO:0140053)
0.0 0.0 GO:0071727 response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.0 0.7 GO:0019236 response to pheromone(GO:0019236)
0.0 0.4 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.1 GO:0032988 ribonucleoprotein complex disassembly(GO:0032988)
0.0 0.4 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:0036015 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.0 1.3 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.4 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.8 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 4.6 GO:0000398 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0 3.8 GO:0006839 mitochondrial transport(GO:0006839)
0.0 0.9 GO:0009261 purine ribonucleotide catabolic process(GO:0009154) ribonucleotide catabolic process(GO:0009261)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.7 GO:0006953 acute-phase response(GO:0006953)
0.0 0.4 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 0.3 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.5 GO:0007606 sensory perception of chemical stimulus(GO:0007606)
0.0 0.2 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.0 0.1 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.0 1.3 GO:0098869 cellular oxidant detoxification(GO:0098869)
0.0 0.1 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.1 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.0 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.0 0.3 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.0 0.3 GO:0006625 protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 0.5 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 1.0 GO:0006342 chromatin silencing(GO:0006342)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 5.0 GO:0033269 internode region of axon(GO:0033269)
0.6 1.7 GO:0005588 collagen type V trimer(GO:0005588)
0.6 2.3 GO:0097447 dendritic tree(GO:0097447)
0.5 1.5 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.4 1.3 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.4 1.6 GO:0000802 transverse filament(GO:0000802)
0.3 0.6 GO:0044420 microfibril(GO:0001527) extracellular matrix component(GO:0044420)
0.3 1.4 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.3 3.7 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.3 1.1 GO:1902636 kinociliary basal body(GO:1902636)
0.3 1.9 GO:0033503 HULC complex(GO:0033503)
0.3 6.8 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich plasma lipoprotein particle(GO:0034385)
0.2 0.9 GO:0005745 m-AAA complex(GO:0005745)
0.2 1.1 GO:1990130 GATOR1 complex(GO:1990130)
0.2 1.5 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.2 2.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.2 0.8 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.2 2.8 GO:0017119 Golgi transport complex(GO:0017119)
0.2 0.6 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
0.2 2.5 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.2 0.9 GO:1990923 PET complex(GO:1990923)
0.2 1.1 GO:0097255 R2TP complex(GO:0097255)
0.2 2.1 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.1 0.6 GO:0035339 SPOTS complex(GO:0035339)
0.1 1.8 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 1.3 GO:0089701 U2AF(GO:0089701)
0.1 0.8 GO:0032133 chromosome passenger complex(GO:0032133)
0.1 2.4 GO:0030061 mitochondrial crista(GO:0030061)
0.1 1.7 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.1 0.4 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.1 1.5 GO:0097208 alveolar lamellar body(GO:0097208)
0.1 1.1 GO:0000813 ESCRT I complex(GO:0000813)
0.1 0.9 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.1 2.6 GO:0031527 filopodium membrane(GO:0031527)
0.1 2.7 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 0.4 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.1 2.9 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 0.8 GO:0070187 shelterin complex(GO:0070187)
0.1 10.0 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 0.6 GO:1990584 cardiac Troponin complex(GO:1990584)
0.1 0.4 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.1 22.6 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 0.9 GO:0000243 commitment complex(GO:0000243)
0.1 7.8 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 1.4 GO:0036038 MKS complex(GO:0036038)
0.1 0.6 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.1 13.0 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 1.4 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 0.7 GO:0061617 MICOS complex(GO:0061617)
0.1 0.5 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 0.7 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.1 2.4 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.1 1.7 GO:0005684 U2-type spliceosomal complex(GO:0005684)
0.1 0.1 GO:0071010 prespliceosome(GO:0071010)
0.1 2.2 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.1 2.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 0.6 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 2.7 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 1.1 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.1 1.3 GO:0000145 exocyst(GO:0000145)
0.1 0.5 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 1.3 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 1.0 GO:0031528 microvillus membrane(GO:0031528)
0.1 0.5 GO:0005675 holo TFIIH complex(GO:0005675)
0.0 9.3 GO:0030018 Z disc(GO:0030018)
0.0 1.9 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 1.0 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.4 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.1 GO:0000814 ESCRT II complex(GO:0000814)
0.0 0.8 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.9 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 1.5 GO:0030141 secretory granule(GO:0030141)
0.0 0.5 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.1 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.0 0.1 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 5.1 GO:0030496 midbody(GO:0030496)
0.0 2.2 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.4 GO:0032009 early phagosome(GO:0032009)
0.0 0.9 GO:0045095 keratin filament(GO:0045095)
0.0 0.1 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.0 0.4 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.6 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.3 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.1 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 11.4 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 0.5 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.2 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.1 GO:0070469 respiratory chain(GO:0070469)
0.0 1.3 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.6 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.6 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 1.4 GO:0005882 intermediate filament(GO:0005882)
0.0 2.0 GO:0005581 collagen trimer(GO:0005581)
0.0 1.7 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.2 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 1.4 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.5 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.3 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.2 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 1.2 GO:0005811 lipid droplet(GO:0005811)
0.0 4.9 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.1 GO:0042588 zymogen granule(GO:0042588)
0.0 0.5 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.1 GO:0031415 NatA complex(GO:0031415)
0.0 1.1 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.9 GO:0005844 polysome(GO:0005844)
0.0 1.2 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.7 GO:0060076 excitatory synapse(GO:0060076)
0.0 0.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.0 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 0.4 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 8.6 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 0.1 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.0 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.8 18.9 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
2.1 6.4 GO:0005333 norepinephrine transmembrane transporter activity(GO:0005333)
2.0 8.1 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
1.4 4.2 GO:0003979 UDP-glucose 6-dehydrogenase activity(GO:0003979)
1.1 4.5 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
1.1 4.3 GO:0004939 beta-adrenergic receptor activity(GO:0004939) beta-3 adrenergic receptor binding(GO:0031699)
0.9 3.8 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.9 2.8 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.8 4.9 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.7 2.1 GO:0070905 serine binding(GO:0070905)
0.6 2.4 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
0.5 4.1 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.5 1.4 GO:0019807 aspartoacylase activity(GO:0019807)
0.5 6.0 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.5 1.4 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
0.4 1.6 GO:0003978 UDP-glucose 4-epimerase activity(GO:0003978) UTP:galactose-1-phosphate uridylyltransferase activity(GO:0017103)
0.4 1.6 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441)
0.4 1.5 GO:0030984 kininogen binding(GO:0030984)
0.4 1.5 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.4 2.2 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.4 2.2 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.4 1.4 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.4 2.1 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.4 1.1 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.3 2.8 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.3 1.6 GO:0016019 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745) peptidoglycan receptor activity(GO:0016019)
0.3 11.6 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.3 1.5 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761)
0.3 3.6 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.3 1.2 GO:0070698 type I activin receptor binding(GO:0070698)
0.3 1.2 GO:0030366 molybdopterin synthase activity(GO:0030366) molybdopterin adenylyltransferase activity(GO:0061598)
0.3 2.2 GO:0019779 Atg8 activating enzyme activity(GO:0019779)
0.3 1.9 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.3 0.3 GO:0004661 protein geranylgeranyltransferase activity(GO:0004661)
0.3 1.6 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.3 2.8 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.3 1.3 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.3 1.0 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.3 0.8 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.2 0.7 GO:0018738 S-formylglutathione hydrolase activity(GO:0018738)
0.2 0.7 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.2 0.7 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.2 2.1 GO:0140035 ubiquitination-like modification-dependent protein binding(GO:0140035) ubiquitin-dependent protein binding(GO:0140036)
0.2 8.8 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.2 2.3 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.2 2.7 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.2 1.3 GO:0005534 galactose binding(GO:0005534)
0.2 2.1 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.2 4.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 1.1 GO:0070287 ferritin receptor activity(GO:0070287)
0.2 1.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.2 0.8 GO:0003998 acylphosphatase activity(GO:0003998)
0.2 0.8 GO:0004452 isopentenyl-diphosphate delta-isomerase activity(GO:0004452)
0.2 4.1 GO:0000030 mannosyltransferase activity(GO:0000030)
0.2 1.3 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.2 1.3 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.2 4.2 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.1 0.6 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 0.7 GO:0005290 L-histidine transmembrane transporter activity(GO:0005290)
0.1 1.6 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.1 1.4 GO:0001055 RNA polymerase II activity(GO:0001055)
0.1 0.6 GO:0035877 death effector domain binding(GO:0035877)
0.1 0.4 GO:0008988 rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) U6 snRNA 3'-end binding(GO:0030629)
0.1 2.4 GO:0019865 immunoglobulin binding(GO:0019865)
0.1 1.1 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.1 1.8 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1 0.3 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.1 4.3 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.1 1.0 GO:0043199 sulfate binding(GO:0043199)
0.1 2.0 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.4 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.1 1.9 GO:0001163 RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.1 1.5 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.6 GO:0089720 caspase binding(GO:0089720)
0.1 0.7 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 0.2 GO:0004825 methionine-tRNA ligase activity(GO:0004825)
0.1 4.3 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 2.6 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 2.3 GO:0003951 NAD+ kinase activity(GO:0003951)
0.1 1.9 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 1.6 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.6 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.1 1.3 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.1 5.9 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.1 0.6 GO:0030172 troponin C binding(GO:0030172)
0.1 3.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 0.5 GO:0030250 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.1 0.6 GO:0001595 angiotensin receptor activity(GO:0001595)
0.1 4.4 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 0.6 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.1 1.6 GO:0017166 vinculin binding(GO:0017166)
0.1 1.5 GO:0035174 histone serine kinase activity(GO:0035174)
0.1 1.6 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 1.5 GO:0016805 dipeptidase activity(GO:0016805)
0.1 0.3 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.1 1.2 GO:0070411 I-SMAD binding(GO:0070411)
0.1 2.0 GO:0043394 proteoglycan binding(GO:0043394)
0.1 1.5 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 1.4 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.1 0.3 GO:0016842 amidine-lyase activity(GO:0016842)
0.1 1.0 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.4 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.1 1.4 GO:0051787 misfolded protein binding(GO:0051787)
0.1 1.4 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.1 1.2 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1 0.7 GO:0042826 histone deacetylase binding(GO:0042826)
0.1 1.8 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 5.4 GO:0008170 N-methyltransferase activity(GO:0008170)
0.1 2.4 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor(GO:0016655)
0.1 1.8 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.1 0.3 GO:0001032 RNA polymerase III type 3 promoter DNA binding(GO:0001032)
0.1 1.8 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.3 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 1.0 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.1 GO:0038075 MAP kinase activity involved in innate immune response(GO:0038075)
0.0 1.5 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 1.2 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.9 GO:0022848 acetylcholine-gated cation-selective channel activity(GO:0022848)
0.0 0.3 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.6 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 0.8 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.4 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.1 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0 0.8 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.4 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.9 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.4 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 1.1 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:0019981 interleukin-6 receptor activity(GO:0004915) leukemia inhibitory factor receptor activity(GO:0004923) interleukin-6 binding(GO:0019981)
0.0 7.3 GO:0061660 Atg12 activating enzyme activity(GO:0019778) Atg8-specific protease activity(GO:0019786) Atg12 conjugating enzyme activity(GO:0061651) Atg12 ligase activity(GO:0061660)
0.0 0.2 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.0 0.1 GO:0048039 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635) ubiquinone binding(GO:0048039)
0.0 0.6 GO:0005123 death receptor binding(GO:0005123)
0.0 0.5 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.4 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.5 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 1.9 GO:0001784 phosphotyrosine residue binding(GO:0001784)
0.0 1.2 GO:0015295 solute:proton symporter activity(GO:0015295)
0.0 0.3 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.3 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.9 GO:0030145 manganese ion binding(GO:0030145)
0.0 1.2 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.4 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.1 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.0 0.8 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.6 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.4 GO:0035325 Toll-like receptor binding(GO:0035325)
0.0 0.1 GO:0052795 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 1.1 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.0 0.3 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.5 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.7 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 0.9 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.9 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.6 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.0 7.4 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 5.7 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.4 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.9 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.1 GO:0098973 structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.0 0.8 GO:0005112 Notch binding(GO:0005112)
0.0 0.9 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.7 GO:0001671 ATPase activator activity(GO:0001671)
0.0 1.8 GO:0008565 protein transporter activity(GO:0008565)
0.0 1.0 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.1 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0 0.8 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 2.6 GO:0005506 iron ion binding(GO:0005506)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.4 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 2.1 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.0 1.1 GO:0038024 cargo receptor activity(GO:0038024)
0.0 0.6 GO:0017069 snRNA binding(GO:0017069)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 2.7 GO:0005125 cytokine activity(GO:0005125)
0.0 0.0 GO:0071723 lipopeptide binding(GO:0071723)
0.0 0.2 GO:0019841 retinal binding(GO:0016918) retinol binding(GO:0019841)
0.0 0.3 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 1.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.4 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.5 GO:0005109 frizzled binding(GO:0005109)
0.0 0.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 4.1 GO:0005525 GTP binding(GO:0005525)
0.0 0.3 GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.0 0.2 GO:0043855 cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.0 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 PID_ECADHERIN_KERATINOCYTE_PATHWAY E-cadherin signaling in keratinocytes
0.2 1.6 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 1.4 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.1 5.1 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.1 2.9 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 2.7 PID_ALK1_PATHWAY ALK1 signaling events
0.1 3.3 NABA_COLLAGENS Genes encoding collagen proteins
0.1 0.6 SA_FAS_SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 4.4 SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES Genes related to the insulin receptor pathway
0.0 0.8 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.0 5.0 PID_NOTCH_PATHWAY Notch signaling pathway
0.0 1.3 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 0.6 PID_IL5_PATHWAY IL5-mediated signaling events
0.0 1.2 ST_G_ALPHA_I_PATHWAY G alpha i Pathway
0.0 2.2 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.4 PID_AURORA_B_PATHWAY Aurora B signaling
0.0 0.4 PID_WNT_CANONICAL_PATHWAY Canonical Wnt signaling pathway
0.0 0.6 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.0 0.8 SIG_CHEMOTAXIS Genes related to chemotaxis
0.0 0.7 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.0 3.4 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.7 PID_ARF6_PATHWAY Arf6 signaling events
0.0 0.6 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.4 PID_P73PATHWAY p73 transcription factor network
0.0 0.9 PID_TELOMERASE_PATHWAY Regulation of Telomerase
0.0 0.9 PID_TCR_PATHWAY TCR signaling in naïve CD4+ T cells

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 6.0 REACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS Genes involved in Recycling of bile acids and salts
0.5 6.7 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.5 6.4 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM Genes involved in Abacavir transport and metabolism
0.4 5.9 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.3 4.4 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.2 8.0 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.2 4.8 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.2 3.6 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.2 4.1 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.2 0.5 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 3.4 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.1 2.9 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 1.4 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 1.6 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 2.8 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 5.2 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 1.0 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 0.9 REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 2.6 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 1.6 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.1 1.4 REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 1.9 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 1.9 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.1 1.6 REACTOME_RNA_POL_I_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.1 0.9 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 1.2 REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS Genes involved in G alpha (z) signalling events
0.1 2.7 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 3.1 REACTOME_CDK_MEDIATED_PHOSPHORYLATION_AND_REMOVAL_OF_CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.1 1.7 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.6 REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 3.2 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.0 1.3 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.8 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.4 REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.6 REACTOME_IRON_UPTAKE_AND_TRANSPORT Genes involved in Iron uptake and transport
0.0 0.7 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.8 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.0 0.3 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.0 1.7 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.0 0.5 REACTOME_FANCONI_ANEMIA_PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.8 REACTOME_IL_RECEPTOR_SHC_SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.3 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.2 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.6 REACTOME_CTLA4_INHIBITORY_SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.9 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 1.4 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.7 REACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING Genes involved in Pre-NOTCH Expression and Processing
0.0 0.3 REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.0 REACTOME_TRAF6_MEDIATED_INDUCTION_OF_TAK1_COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.0 0.5 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 2.0 REACTOME_G_ALPHA_S_SIGNALLING_EVENTS Genes involved in G alpha (s) signalling events
0.0 1.1 REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.1 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.1 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.7 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis