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GSE58827: Dynamics of the Mouse Liver

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Results for Pknox2_Pknox1

Z-value: 0.71

Motif logo

Transcription factors associated with Pknox2_Pknox1

Gene Symbol Gene ID Gene Info
ENSMUSG00000035934.9 Pbx/knotted 1 homeobox 2
ENSMUSG00000006705.6 Pbx/knotted 1 homeobox

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Pknox1mm10_v2_chr17_+_31564749_315648540.202.4e-01Click!
Pknox2mm10_v2_chr9_-_37147257_37147323-0.144.3e-01Click!

Activity profile of Pknox2_Pknox1 motif

Sorted Z-values of Pknox2_Pknox1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_66945019 4.60 ENSMUST00000027151.5
myosin, light polypeptide 1
chr1_-_66945361 3.80 ENSMUST00000160100.1
myosin, light polypeptide 1
chr1_+_136052804 1.95 ENSMUST00000112064.1
calcium channel, voltage-dependent, L type, alpha 1S subunit
chr1_+_136052750 1.91 ENSMUST00000160641.1
calcium channel, voltage-dependent, L type, alpha 1S subunit
chr1_+_136052771 1.88 ENSMUST00000112068.3
calcium channel, voltage-dependent, L type, alpha 1S subunit
chr2_-_76982455 1.68 ENSMUST00000011934.5
ENSMUST00000099981.2
ENSMUST00000099980.3
ENSMUST00000111882.2
ENSMUST00000140091.1
titin
chr9_-_31913462 1.44 ENSMUST00000116615.3
BarH-like homeobox 2
chr7_-_131410325 1.16 ENSMUST00000154602.1
IKAROS family zinc finger 5
chr1_-_87101590 1.16 ENSMUST00000113270.2
alkaline phosphatase, intestinal
chr5_-_138619653 1.00 ENSMUST00000129832.1
zinc finger protein 68
chr2_+_152911311 0.96 ENSMUST00000028970.7
myosin, light polypeptide kinase 2, skeletal muscle
chr17_-_48432723 0.83 ENSMUST00000046549.3
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2
chr10_-_123196916 0.79 ENSMUST00000020334.7
ubiquitin specific peptidase 15
chr1_+_87124946 0.77 ENSMUST00000044878.3
alkaline phosphatase 3, intestine, not Mn requiring
chr5_-_138619751 0.74 ENSMUST00000085852.4
ENSMUST00000110905.2
zinc finger protein 68
chr2_+_162987502 0.74 ENSMUST00000117123.1
serum/glucocorticoid regulated kinase 2
chr7_-_131410495 0.73 ENSMUST00000121033.1
ENSMUST00000046306.8
IKAROS family zinc finger 5
chr16_-_11176056 0.71 ENSMUST00000142389.1
ENSMUST00000138185.1
zinc finger CCCH type containing 7 A
chr18_+_49832622 0.70 ENSMUST00000180611.1
Dmx-like 1
chr3_+_107631322 0.69 ENSMUST00000106703.1
predicted gene 10961
chr2_+_162987330 0.66 ENSMUST00000018012.7
serum/glucocorticoid regulated kinase 2
chr10_-_7792795 0.64 ENSMUST00000065124.1
RIKEN cDNA 6530403G13 gene
chr5_-_138619702 0.64 ENSMUST00000063262.4
zinc finger protein 68
chr9_+_113930934 0.63 ENSMUST00000084885.5
ENSMUST00000009885.7
upstream binding protein 1
chr6_-_106800051 0.59 ENSMUST00000013882.7
ENSMUST00000049675.4
ENSMUST00000113239.3
cereblon
chr7_-_48881032 0.59 ENSMUST00000058745.8
E2F transcription factor 8
chr2_-_132578128 0.58 ENSMUST00000028822.7
glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
chr17_-_24141542 0.57 ENSMUST00000115411.1
ENSMUST00000115409.2
ENSMUST00000115407.2
ENSMUST00000102927.3
3-phosphoinositide dependent protein kinase 1
chr2_-_132578244 0.57 ENSMUST00000110142.1
glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
chr8_+_20136455 0.52 ENSMUST00000179299.1
ENSMUST00000096485.4
predicted gene, 21811
chr10_+_50592669 0.52 ENSMUST00000035606.8
activating signal cointegrator 1 complex subunit 3
chr8_+_3655762 0.51 ENSMUST00000012849.8
ENSMUST00000169234.2
resistin
chr12_-_24493656 0.50 ENSMUST00000073088.2
predicted pseudogene 16372
chrX_+_49463926 0.49 ENSMUST00000130558.1
Rho GTPase activating protein 36
chr5_+_93268247 0.48 ENSMUST00000121127.1
cyclin G2
chr13_-_24206281 0.48 ENSMUST00000123076.1
leucine rich repeat containing 16A
chr2_-_132578155 0.46 ENSMUST00000110136.1
ENSMUST00000124107.1
ENSMUST00000060955.5
glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
chr8_+_19682268 0.44 ENSMUST00000153710.1
ENSMUST00000127799.1
predicted gene 6483
chr2_+_130012336 0.44 ENSMUST00000110299.2
transglutaminase 3, E polypeptide
chr9_+_123366921 0.42 ENSMUST00000038863.7
leucyl-tRNA synthetase, mitochondrial
chr2_-_113758638 0.41 ENSMUST00000099575.3
gremlin 1
chrX_-_109013389 0.39 ENSMUST00000033597.8
high-mobility group nucleosome binding domain 5
chr10_+_7792891 0.38 ENSMUST00000015901.4
peptidylprolyl isomerase (cyclophilin)-like 4
chr1_-_179546261 0.37 ENSMUST00000027769.5
transcription factor B2, mitochondrial
chr14_+_54640952 0.36 ENSMUST00000169818.2
predicted gene, 17606
chr8_+_25601591 0.36 ENSMUST00000155861.1
Wolf-Hirschhorn syndrome candidate 1-like 1 (human)
chr11_+_78324200 0.34 ENSMUST00000102478.3
aldolase C, fructose-bisphosphate
chr6_-_71262232 0.34 ENSMUST00000129630.2
ENSMUST00000114186.2
ENSMUST00000074301.3
SET and MYND domain containing 1
chr17_-_66077022 0.33 ENSMUST00000150766.1
ENSMUST00000038116.5
ankyrin repeat domain 12
chr9_+_67840386 0.32 ENSMUST00000077879.5
vacuolar protein sorting 13C (yeast)
chr10_+_34297421 0.32 ENSMUST00000047935.6
TSPY-like 4
chr5_-_71548190 0.31 ENSMUST00000050129.5
cytochrome c oxidase subunit VIIb2
chr5_-_100500592 0.31 ENSMUST00000149714.1
ENSMUST00000046154.5
lin-54 homolog (C. elegans)
chr10_+_41810528 0.30 ENSMUST00000099931.3
sestrin 1
chr18_+_63708689 0.30 ENSMUST00000072726.5
WD repeat domain 7
chr7_-_48881596 0.30 ENSMUST00000119223.1
E2F transcription factor 8
chr19_-_44069690 0.29 ENSMUST00000169092.1
ER lipid raft associated 1
chr10_-_62651194 0.29 ENSMUST00000020270.4
DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
chr8_-_111522073 0.29 ENSMUST00000034437.6
ENSMUST00000038193.7
WD repeat domain 59
chr1_-_180195902 0.28 ENSMUST00000161746.1
aarF domain containing kinase 3
chr10_-_42276688 0.27 ENSMUST00000175881.1
ENSMUST00000056974.3
forkhead box O3
chr6_-_48445373 0.26 ENSMUST00000114563.1
ENSMUST00000114558.1
ENSMUST00000101443.3
ENSMUST00000114564.1
zinc finger protein 467
chr11_+_23256001 0.26 ENSMUST00000020538.6
ENSMUST00000109551.1
ENSMUST00000102870.1
ENSMUST00000102869.1
exportin 1, CRM1 homolog (yeast)
chr3_-_51560816 0.26 ENSMUST00000037141.7
SET domain containing (lysine methyltransferase) 7
chr2_+_146855861 0.26 ENSMUST00000099278.2
ENSMUST00000156232.1
polo-like kinase 1 substrate 1
chr7_+_13398115 0.26 ENSMUST00000005791.7
calcium binding protein 5
chr1_-_58973421 0.25 ENSMUST00000173590.1
ENSMUST00000027186.5
trafficking protein, kinesin binding 2
chr2_-_160872829 0.24 ENSMUST00000176141.1
zinc fingers and homeoboxes 3
chr13_+_109685994 0.24 ENSMUST00000074103.5
phosphodiesterase 4D, cAMP specific
chr8_+_56294552 0.23 ENSMUST00000034026.8
hydroxyprostaglandin dehydrogenase 15 (NAD)
chr13_+_46669517 0.23 ENSMUST00000099547.3
expressed sequence C78339
chr11_-_78386558 0.23 ENSMUST00000108294.1
forkhead box N1
chr11_-_98022594 0.22 ENSMUST00000103144.3
ENSMUST00000017552.6
ENSMUST00000092736.4
ENSMUST00000107562.1
calcium channel, voltage-dependent, beta 1 subunit
chr15_-_81843699 0.22 ENSMUST00000092020.2
predicted gene 8444
chr16_+_23107413 0.22 ENSMUST00000023599.6
ENSMUST00000168891.1
eukaryotic translation initiation factor 4A2
chr10_-_42276744 0.21 ENSMUST00000105502.1
ENSMUST00000105501.1
forkhead box O3
chr15_+_99591028 0.21 ENSMUST00000169082.1
aquaporin 5
chr3_-_79567679 0.20 ENSMUST00000076136.4
folliculin interacting protein 2
chr19_+_6047081 0.19 ENSMUST00000025723.8
synovial apoptosis inhibitor 1, synoviolin
chr5_-_25498702 0.19 ENSMUST00000173073.1
ENSMUST00000045291.7
lysine (K)-specific methyltransferase 2C
chr13_-_58274121 0.19 ENSMUST00000091579.4
G kinase anchoring protein 1
chr4_+_106911517 0.18 ENSMUST00000072753.6
ENSMUST00000097934.3
single-stranded DNA binding protein 3
chr11_+_3202908 0.18 ENSMUST00000179770.1
ENSMUST00000110048.1
eukaryotic translation initiation factor 4E nuclear import factor 1
chr3_+_116594959 0.18 ENSMUST00000029571.8
spindle assembly 6 homolog (C. elegans)
chr14_+_55575617 0.17 ENSMUST00000022826.5
fat storage-inducing transmembrane protein 1
chr19_+_6047055 0.17 ENSMUST00000134667.1
synovial apoptosis inhibitor 1, synoviolin
chr1_+_85793411 0.17 ENSMUST00000113360.1
ENSMUST00000126962.1
calcium binding protein 39
chr5_+_137553517 0.16 ENSMUST00000136088.1
ENSMUST00000139395.1
ENSMUST00000136565.1
ENSMUST00000149292.1
ENSMUST00000125489.1
actin-like 6B
chr4_+_11758147 0.16 ENSMUST00000029871.5
ENSMUST00000108303.1
cadherin 17
chr6_+_95117740 0.16 ENSMUST00000032107.7
ENSMUST00000119582.1
kelch repeat and BTB (POZ) domain containing 8
chr9_-_71771535 0.15 ENSMUST00000122065.1
ENSMUST00000121322.1
ENSMUST00000072899.2
cingulin-like 1
chr8_+_47824459 0.15 ENSMUST00000038693.6
claudin 22
chr16_-_43979050 0.15 ENSMUST00000165648.1
ENSMUST00000036321.7
zinc finger, DHHC domain containing 23
chr19_-_44069526 0.14 ENSMUST00000170801.1
ER lipid raft associated 1
chr2_-_160872985 0.14 ENSMUST00000109460.1
ENSMUST00000127201.1
zinc fingers and homeoboxes 3
chr19_+_11965817 0.14 ENSMUST00000025590.9
oxysterol binding protein
chr1_-_74588117 0.14 ENSMUST00000066986.6
zinc finger protein 142
chr13_-_12106945 0.14 ENSMUST00000021750.7
ENSMUST00000170156.2
ryanodine receptor 2, cardiac
chr4_-_47010781 0.13 ENSMUST00000135777.1
predicted gene 568
chr8_+_55940453 0.13 ENSMUST00000000275.7
glycine receptor, alpha 3 subunit
chr9_-_82975475 0.13 ENSMUST00000034787.5
pleckstrin homology domain interacting protein
chr1_+_156558759 0.12 ENSMUST00000173929.1
v-abl Abelson murine leukemia viral oncogene 2 (arg, Abelson-related gene)
chr19_-_44069736 0.12 ENSMUST00000172041.1
ENSMUST00000071698.6
ENSMUST00000112028.3
ER lipid raft associated 1
chr7_+_112225856 0.12 ENSMUST00000050149.5
ENSMUST00000106647.1
ENSMUST00000106648.1
microtubule associated monooxygenase, calponin and LIM domain containing 2
chr17_+_23898717 0.12 ENSMUST00000088598.5
demilune cell and parotid protein 2
chr11_-_80080928 0.11 ENSMUST00000103233.3
ENSMUST00000061283.8
cytokine receptor-like factor 3
chr4_-_155043143 0.11 ENSMUST00000135665.2
phospholipase C, eta 2
chr18_+_56432116 0.10 ENSMUST00000070166.5
GRAM domain containing 3
chr3_-_84270782 0.10 ENSMUST00000054990.4
tripartite motif-containing 2
chrX_-_60893430 0.10 ENSMUST00000135107.2
SRY-box containing gene 3
chr3_+_51415986 0.10 ENSMUST00000029303.7
N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chr17_+_30624354 0.09 ENSMUST00000170651.1
dynein, axonemal, heavy chain 8
chr11_-_49712674 0.09 ENSMUST00000020624.6
ENSMUST00000145353.1
CCR4-NOT transcription complex, subunit 6
chr10_+_82699007 0.09 ENSMUST00000020478.7
host cell factor C2
chr2_-_91649751 0.08 ENSMUST00000099714.3
zinc finger protein 408
chr4_+_106911470 0.08 ENSMUST00000030367.8
ENSMUST00000149926.1
single-stranded DNA binding protein 3
chr1_-_52727457 0.08 ENSMUST00000156876.1
ENSMUST00000087701.3
major facilitator superfamily domain containing 6
chr11_+_72796254 0.08 ENSMUST00000069395.5
zinc finger, ZZ-type with EF hand domain 1
chr7_-_126584578 0.08 ENSMUST00000150311.1
ceroid lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease)
chr11_-_72796028 0.08 ENSMUST00000156294.1
cytochrome b5 domain containing 2
chr8_+_76899772 0.08 ENSMUST00000109913.2
nuclear receptor subfamily 3, group C, member 2
chr6_-_48445678 0.07 ENSMUST00000114556.1
zinc finger protein 467
chr11_+_83964419 0.07 ENSMUST00000049714.8
ENSMUST00000092834.5
ENSMUST00000183714.1
ENSMUST00000183456.1
synergin, gamma
chr16_+_55973881 0.06 ENSMUST00000050248.8
ribosomal protein L24
chr1_+_58973521 0.06 ENSMUST00000114296.1
ENSMUST00000027185.4
STE20-related kinase adaptor beta
chr5_+_138820080 0.06 ENSMUST00000179205.1
predicted gene 5294
chr7_+_98703091 0.06 ENSMUST00000033009.9
protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)
chr2_+_111780313 0.06 ENSMUST00000054004.1
olfactory receptor 1302
chr11_-_72795801 0.06 ENSMUST00000079681.5
cytochrome b5 domain containing 2
chr8_+_94386486 0.06 ENSMUST00000034220.7
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr2_+_153492790 0.06 ENSMUST00000109783.1
RIKEN cDNA 4930404H24 gene
chr7_+_25221417 0.06 ENSMUST00000055604.4
zinc finger protein 526
chr8_-_91134027 0.06 ENSMUST00000125257.1
thymoma viral proto-oncogene 1 interacting protein
chr1_+_106938953 0.05 ENSMUST00000112724.2
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 12
chr3_-_89402650 0.05 ENSMUST00000168325.1
ENSMUST00000057431.5
lens epithelial protein
chr2_-_91649785 0.05 ENSMUST00000111333.1
zinc finger protein 408
chr9_+_107928440 0.04 ENSMUST00000085073.1
actin-like 11
chr8_-_91133942 0.04 ENSMUST00000120213.1
ENSMUST00000109609.2
thymoma viral proto-oncogene 1 interacting protein
chrX_-_102505359 0.04 ENSMUST00000087916.4
histone deacetylase 8
chr11_+_72796164 0.04 ENSMUST00000172220.1
zinc finger, ZZ-type with EF hand domain 1
chr11_-_4594750 0.04 ENSMUST00000109943.3
myotubularin related protein 3
chr7_+_13398150 0.04 ENSMUST00000117400.1
calcium binding protein 5
chr1_-_36244245 0.04 ENSMUST00000046875.7
UDP-glucose glycoprotein glucosyltransferase 1
chr9_+_68653761 0.03 ENSMUST00000034766.7
RAR-related orphan receptor alpha
chr5_-_122779278 0.03 ENSMUST00000111668.3
calcium/calmodulin-dependent protein kinase kinase 2, beta
chr3_-_108445183 0.03 ENSMUST00000090553.5
ENSMUST00000153499.1
seryl-aminoacyl-tRNA synthetase
chr17_+_35533194 0.02 ENSMUST00000025273.8
psoriasis susceptibility 1 candidate 2 (human)
chr2_+_128967383 0.02 ENSMUST00000110320.2
ENSMUST00000110319.2
zinc finger CCCH type containing 6
chr9_+_21424984 0.02 ENSMUST00000172482.1
ENSMUST00000174050.1
dynamin 2
chr17_+_23917455 0.02 ENSMUST00000115428.1
demilune cell and parotid protein 3
chr19_+_32757497 0.01 ENSMUST00000013807.7
phosphatase and tensin homolog
chr15_-_59374149 0.01 ENSMUST00000022976.4
RIKEN cDNA E430025E21 gene
chr7_-_126584220 0.01 ENSMUST00000128970.1
ENSMUST00000116269.2
ceroid lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease)
chr6_-_48445825 0.01 ENSMUST00000114561.2
zinc finger protein 467
chr18_+_40256960 0.01 ENSMUST00000096572.1
RIKEN cDNA 2900055J20 gene
chr6_+_88724489 0.01 ENSMUST00000113581.1
monoglyceride lipase
chr11_+_99857915 0.01 ENSMUST00000107434.1
predicted gene 11568
chr4_-_119218165 0.00 ENSMUST00000030394.2
RIKEN cDNA 4930538K18 gene

Network of associatons between targets according to the STRING database.

First level regulatory network of Pknox2_Pknox1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 5.7 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.4 1.7 GO:0043056 forward locomotion(GO:0043056)
0.3 0.9 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.2 1.0 GO:0031446 regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
0.2 0.4 GO:1900157 regulation of bone mineralization involved in bone maturation(GO:1900157)
0.2 0.5 GO:2000872 positive regulation of progesterone secretion(GO:2000872)
0.2 0.8 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1 1.4 GO:0042637 catagen(GO:0042637)
0.1 1.6 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1 0.3 GO:0097065 anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.1 0.8 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 0.2 GO:0097534 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.1 0.5 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.1 0.5 GO:1901300 positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300)
0.1 0.7 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 0.6 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1 0.2 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 0.1 GO:0003220 left ventricular cardiac muscle tissue morphogenesis(GO:0003220)
0.0 0.3 GO:1904923 parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734) negative regulation of macromitophagy(GO:1901525) regulation of mitophagy in response to mitochondrial depolarization(GO:1904923)
0.0 0.6 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 8.6 GO:0060048 cardiac muscle contraction(GO:0060048)
0.0 0.4 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 0.4 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.0 0.3 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.3 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.2 GO:0007199 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
0.0 0.8 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 0.6 GO:0006972 hyperosmotic response(GO:0006972)
0.0 0.3 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.2 GO:0015670 carbon dioxide transport(GO:0015670)
0.0 0.1 GO:0031959 mineralocorticoid receptor signaling pathway(GO:0031959)
0.0 0.3 GO:0098935 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.0 0.1 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.2 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.3 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.1 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.0 0.1 GO:2000327 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966) regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.0 0.4 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0 0.1 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.2 GO:0007567 parturition(GO:0007567)
0.0 0.0 GO:1901630 negative regulation of presynaptic membrane organization(GO:1901630)
0.0 0.2 GO:0014029 neural crest formation(GO:0014029)
0.0 0.1 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.0 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0 0.1 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.4 GO:0031424 keratinization(GO:0031424)
0.0 1.3 GO:0032411 positive regulation of transporter activity(GO:0032411)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.2 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 10.2 GO:0016459 myosin complex(GO:0016459)
0.1 0.4 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.6 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.6 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.2 GO:0098536 deuterosome(GO:0098536)
0.0 0.3 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.3 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.4 GO:0001533 cornified envelope(GO:0001533)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)
0.0 0.1 GO:0031415 NatA complex(GO:0031415)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.3 6.0 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.3 1.9 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.2 1.7 GO:0031433 telethonin binding(GO:0031433)
0.1 0.8 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 1.0 GO:0032027 myosin light chain kinase activity(GO:0004687) myosin light chain binding(GO:0032027)
0.1 0.8 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 0.4 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1 0.4 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1 1.4 GO:0017081 chloride channel regulator activity(GO:0017081)
0.1 0.5 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.1 0.4 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.2 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.1 0.3 GO:0070728 leucine binding(GO:0070728)
0.0 0.1 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0 0.3 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.6 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 0.2 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.2 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.4 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
0.0 0.4 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.1 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.8 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.3 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.2 GO:0015250 water channel activity(GO:0015250)
0.0 9.1 GO:0005509 calcium ion binding(GO:0005509)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.5 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 0.5 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 8.4 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 6.0 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.1 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.4 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.3 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.3 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.2 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.3 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 1.4 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis