Motif ID: Pou2f2_Pou3f1

Z-value: 1.419

Transcription factors associated with Pou2f2_Pou3f1:

Gene SymbolEntrez IDGene Name
Pou2f2 ENSMUSG00000008496.12 Pou2f2
Pou3f1 ENSMUSG00000090125.2 Pou3f1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pou3f1mm10_v2_chr4_+_124657646_124657656-0.299.1e-02Click!
Pou2f2mm10_v2_chr7_-_25132473_251325120.222.1e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Pou2f2_Pou3f1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_+_23746734 11.160 ENSMUST00000099703.2
Hist1h2bb
histone cluster 1, H2bb
chr3_+_96269695 9.638 ENSMUST00000051089.3
ENSMUST00000177113.1
Hist2h2bb

histone cluster 2, H2bb

chr13_+_21722057 8.822 ENSMUST00000110476.3
Hist1h2bm
histone cluster 1, H2bm
chrX_+_93675088 6.710 ENSMUST00000045898.3
Pcyt1b
phosphate cytidylyltransferase 1, choline, beta isoform
chr11_+_58948890 6.424 ENSMUST00000078267.3
Hist3h2ba
histone cluster 3, H2ba
chr10_-_80421847 5.573 ENSMUST00000156244.1
Tcf3
transcription factor 3
chr7_-_102100227 5.549 ENSMUST00000106937.1
Art5
ADP-ribosyltransferase 5
chr13_-_21833575 5.349 ENSMUST00000081342.5
Hist1h2ap
histone cluster 1, H2ap
chr16_+_17144600 5.067 ENSMUST00000115702.1
Ydjc
YdjC homolog (bacterial)
chr7_+_24507006 5.046 ENSMUST00000176880.1
Zfp428
zinc finger protein 428
chr13_+_22043189 5.028 ENSMUST00000110452.1
Hist1h2bj
histone cluster 1, H2bj
chr13_+_23751069 4.887 ENSMUST00000078369.1
Hist1h2ab
histone cluster 1, H2ab
chr16_-_17144415 4.785 ENSMUST00000115709.1
Ccdc116
coiled-coil domain containing 116
chr5_+_76656512 4.759 ENSMUST00000086909.4
Gm10430
predicted gene 10430
chr2_-_170194033 4.640 ENSMUST00000180625.1
Gm17619
predicted gene, 17619
chr15_-_66831625 4.619 ENSMUST00000164163.1
Sla
src-like adaptor
chr7_+_24507122 4.600 ENSMUST00000177205.1
Zfp428
zinc finger protein 428
chr6_-_67037399 4.587 ENSMUST00000043098.6
Gadd45a
growth arrest and DNA-damage-inducible 45 alpha
chr13_-_23571151 4.561 ENSMUST00000102969.3
Hist1h2ae
histone cluster 1, H2ae
chr13_-_22042949 4.515 ENSMUST00000091741.4
Hist1h2ag
histone cluster 1, H2ag
chr14_+_27000362 4.452 ENSMUST00000035433.8
Hesx1
homeobox gene expressed in ES cells
chr13_-_23683941 4.417 ENSMUST00000171127.1
Hist1h2ac
histone cluster 1, H2ac
chr11_+_95337012 4.002 ENSMUST00000037502.6
Fam117a
family with sequence similarity 117, member A
chr7_+_24507057 3.911 ENSMUST00000071361.6
Zfp428
zinc finger protein 428
chr13_+_23544052 3.905 ENSMUST00000075558.2
Hist1h3f
histone cluster 1, H3f
chr3_+_51661167 3.793 ENSMUST00000099106.3
Mgst2
microsomal glutathione S-transferase 2
chr19_+_47228804 3.763 ENSMUST00000111807.3
Neurl1a
neuralized homolog 1A (Drosophila)
chr12_-_36042476 3.626 ENSMUST00000020896.8
Tspan13
tetraspanin 13
chr11_+_58954675 3.558 ENSMUST00000047697.5
ENSMUST00000108817.3
Trim17
Hist3h2a
tripartite motif-containing 17
histone cluster 3, H2a
chr11_-_69605829 3.506 ENSMUST00000047889.6
Atp1b2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr8_+_22974844 3.501 ENSMUST00000110688.2
ENSMUST00000121802.2
Ank1

ankyrin 1, erythroid

chr1_+_91540553 3.446 ENSMUST00000027538.7
Asb1
ankyrin repeat and SOCS box-containing 1
chr10_+_75948292 3.353 ENSMUST00000000926.2
Vpreb3
pre-B lymphocyte gene 3
chrX_+_56454871 3.270 ENSMUST00000039374.2
ENSMUST00000101553.2
Ddx26b

DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B

chr7_+_126776939 3.151 ENSMUST00000038614.5
ENSMUST00000170882.1
ENSMUST00000106359.1
ENSMUST00000106357.1
ENSMUST00000145762.1
ENSMUST00000132643.1
ENSMUST00000106356.1
Ypel3






yippee-like 3 (Drosophila)






chr1_-_89933290 3.100 ENSMUST00000036954.7
Gbx2
gastrulation brain homeobox 2
chr13_+_22035821 2.999 ENSMUST00000110455.2
Hist1h2bk
histone cluster 1, H2bk
chr6_-_56901870 2.743 ENSMUST00000101367.2
Nt5c3
5'-nucleotidase, cytosolic III
chr12_-_114416895 2.678 ENSMUST00000179796.1
Ighv6-5
immunoglobulin heavy variable V6-5
chr13_-_22035589 2.672 ENSMUST00000091742.4
Hist1h2ah
histone cluster 1, H2ah
chr13_+_23574381 2.638 ENSMUST00000090776.4
Hist1h2ad
histone cluster 1, H2ad
chr17_+_27556641 2.620 ENSMUST00000119486.1
ENSMUST00000118599.1
Hmga1

high mobility group AT-hook 1

chr5_+_76840597 2.596 ENSMUST00000120639.2
ENSMUST00000163347.1
ENSMUST00000121851.1
C530008M17Rik


RIKEN cDNA C530008M17 gene


chr17_+_27556668 2.587 ENSMUST00000117254.1
ENSMUST00000118570.1
Hmga1

high mobility group AT-hook 1

chr7_+_45017953 2.546 ENSMUST00000044111.7
Rras
Harvey rat sarcoma oncogene, subgroup R
chr7_+_24507099 2.503 ENSMUST00000177228.1
Zfp428
zinc finger protein 428
chr17_+_27556613 2.469 ENSMUST00000117600.1
ENSMUST00000114888.3
Hmga1

high mobility group AT-hook 1

chr9_+_21936986 2.446 ENSMUST00000046371.6
BC018242
cDNA sequence BC018242
chr13_+_21810428 2.428 ENSMUST00000091745.5
Hist1h2ao
histone cluster 1, H2ao
chr4_-_128806045 2.427 ENSMUST00000106072.2
ENSMUST00000170934.1
Zfp362

zinc finger protein 362

chrX_+_133850980 2.408 ENSMUST00000033602.8
Tnmd
tenomodulin
chr16_-_92697315 2.332 ENSMUST00000168195.1
ENSMUST00000113956.3
Runx1

runt related transcription factor 1

chr7_-_102099932 2.329 ENSMUST00000106934.1
Art5
ADP-ribosyltransferase 5
chr2_+_25180737 2.307 ENSMUST00000104999.2
Nrarp
Notch-regulated ankyrin repeat protein
chr15_+_62039216 2.264 ENSMUST00000183297.1
Pvt1
plasmacytoma variant translocation 1
chr2_-_152398046 2.246 ENSMUST00000063332.8
ENSMUST00000182625.1
Sox12

SRY-box containing gene 12

chr13_+_23533869 2.225 ENSMUST00000073261.2
Hist1h2af
histone cluster 1, H2af
chr11_-_106314494 2.209 ENSMUST00000167143.1
Cd79b
CD79B antigen
chr4_-_140810646 2.197 ENSMUST00000026377.2
Padi3
peptidyl arginine deiminase, type III
chr3_+_83766300 2.168 ENSMUST00000029625.7
Sfrp2
secreted frizzled-related protein 2
chr7_+_127746775 2.148 ENSMUST00000033081.7
Fbxl19
F-box and leucine-rich repeat protein 19
chr5_+_137629169 2.122 ENSMUST00000176667.1
Lrch4
leucine-rich repeats and calponin homology (CH) domain containing 4
chr4_+_152039315 2.069 ENSMUST00000084116.6
ENSMUST00000105663.1
ENSMUST00000103197.3
Nol9


nucleolar protein 9


chr2_+_119047116 2.048 ENSMUST00000152380.1
ENSMUST00000099542.2
Casc5

cancer susceptibility candidate 5

chr7_+_98838845 1.964 ENSMUST00000167303.1
Wnt11
wingless-related MMTV integration site 11
chr16_-_92826004 1.913 ENSMUST00000023673.7
Runx1
runt related transcription factor 1
chr1_-_144567667 1.909 ENSMUST00000184008.1
Rgs21
regulator of G-protein signalling 21
chr9_-_70421533 1.888 ENSMUST00000034742.6
Ccnb2
cyclin B2
chrX_-_167209149 1.885 ENSMUST00000112176.1
Tmsb4x
thymosin, beta 4, X chromosome
chr3_-_50443603 1.855 ENSMUST00000029297.4
Slc7a11
solute carrier family 7 (cationic amino acid transporter, y+ system), member 11
chr3_+_159495408 1.851 ENSMUST00000120272.1
ENSMUST00000029825.7
ENSMUST00000106041.2
Depdc1a


DEP domain containing 1a


chr13_+_5861489 1.838 ENSMUST00000000080.6
Klf6
Kruppel-like factor 6
chr14_-_79771305 1.832 ENSMUST00000039568.5
Pcdh8
protocadherin 8
chr5_+_137630116 1.822 ENSMUST00000175968.1
Lrch4
leucine-rich repeats and calponin homology (CH) domain containing 4
chr16_-_19883873 1.733 ENSMUST00000100083.3
A930003A15Rik
RIKEN cDNA A930003A15 gene
chr12_-_79192248 1.708 ENSMUST00000161204.1
Rdh11
retinol dehydrogenase 11
chr4_-_3938354 1.689 ENSMUST00000003369.3
Plag1
pleiomorphic adenoma gene 1
chr9_+_71215779 1.683 ENSMUST00000034723.5
Aldh1a2
aldehyde dehydrogenase family 1, subfamily A2
chr17_-_58991343 1.667 ENSMUST00000025064.7
2610034M16Rik
RIKEN cDNA 2610034M16 gene
chr10_+_79927039 1.658 ENSMUST00000019708.5
ENSMUST00000105377.1
Arid3a

AT rich interactive domain 3A (BRIGHT-like)

chr19_+_8941865 1.654 ENSMUST00000096240.2
Mta2
metastasis-associated gene family, member 2
chr10_+_79927330 1.652 ENSMUST00000105376.1
Arid3a
AT rich interactive domain 3A (BRIGHT-like)
chr2_+_119047129 1.638 ENSMUST00000153300.1
ENSMUST00000028799.5
Casc5

cancer susceptibility candidate 5

chr3_+_92365178 1.634 ENSMUST00000050397.1
Sprr2f
small proline-rich protein 2F
chr14_-_66868572 1.623 ENSMUST00000022629.8
Dpysl2
dihydropyrimidinase-like 2
chr3_-_144849301 1.602 ENSMUST00000159989.1
Clca4
chloride channel calcium activated 4
chr6_+_136518820 1.593 ENSMUST00000032335.6
Atf7ip
activating transcription factor 7 interacting protein
chr19_-_46044914 1.576 ENSMUST00000026252.7
Ldb1
LIM domain binding 1
chr13_+_21833736 1.568 ENSMUST00000180288.1
ENSMUST00000110467.1
Hist1h2br

histone cluster 1 H2br

chr6_-_148946146 1.565 ENSMUST00000132696.1
Fam60a
family with sequence similarity 60, member A
chr6_-_52240841 1.557 ENSMUST00000121043.1
Hoxa10
homeobox A10
chr3_+_130180882 1.544 ENSMUST00000106353.1
ENSMUST00000080335.4
Col25a1

collagen, type XXV, alpha 1

chr5_-_147307264 1.531 ENSMUST00000031650.3
Cdx2
caudal type homeobox 2
chr2_-_160912292 1.526 ENSMUST00000109454.1
ENSMUST00000057169.4
Emilin3

elastin microfibril interfacer 3

chr7_-_143460989 1.524 ENSMUST00000167912.1
ENSMUST00000037287.6
Cdkn1c

cyclin-dependent kinase inhibitor 1C (P57)

chr13_-_21787218 1.516 ENSMUST00000091751.2
Hist1h2an
histone cluster 1, H2an
chr19_-_46045194 1.506 ENSMUST00000156585.1
ENSMUST00000152946.1
Ldb1

LIM domain binding 1

chr12_-_114406773 1.492 ENSMUST00000177949.1
Ighv6-4
immunoglobulin heavy variable V6-4
chr4_-_152477433 1.490 ENSMUST00000159186.1
ENSMUST00000162017.1
ENSMUST00000030768.2
Kcnab2


potassium voltage-gated channel, shaker-related subfamily, beta member 2


chr8_+_120488416 1.464 ENSMUST00000034279.9
Gse1
genetic suppressor element 1
chr6_-_13839916 1.460 ENSMUST00000060442.7
Gpr85
G protein-coupled receptor 85
chr6_+_145145473 1.459 ENSMUST00000156849.1
ENSMUST00000132948.1
Lrmp

lymphoid-restricted membrane protein

chr2_+_160645881 1.452 ENSMUST00000109468.2
Top1
topoisomerase (DNA) I
chr11_+_61208621 1.449 ENSMUST00000108716.1
ENSMUST00000019246.3
Aldh3a1

aldehyde dehydrogenase family 3, subfamily A1

chr11_+_96282529 1.440 ENSMUST00000125410.1
Hoxb8
homeobox B8
chr16_+_91729281 1.440 ENSMUST00000114001.1
ENSMUST00000113999.1
ENSMUST00000064797.5
ENSMUST00000114002.2
ENSMUST00000095909.3
ENSMUST00000056482.7
ENSMUST00000113996.1
Itsn1






intersectin 1 (SH3 domain protein 1A)






chr8_-_122460666 1.378 ENSMUST00000006762.5
Snai3
snail homolog 3 (Drosophila)
chr3_+_92316705 1.363 ENSMUST00000061038.2
Sprr2b
small proline-rich protein 2B
chr9_-_22389113 1.347 ENSMUST00000040912.7
Anln
anillin, actin binding protein
chr17_+_29490812 1.341 ENSMUST00000024811.6
Pim1
proviral integration site 1
chr12_-_17324703 1.333 ENSMUST00000020884.9
ENSMUST00000095820.5
ENSMUST00000127185.1
Atp6v1c2


ATPase, H+ transporting, lysosomal V1 subunit C2


chr7_+_82174796 1.306 ENSMUST00000032874.7
Sh3gl3
SH3-domain GRB2-like 3
chr11_-_34833631 1.301 ENSMUST00000093191.2
Spdl1
spindle apparatus coiled-coil protein 1
chr2_-_152830266 1.286 ENSMUST00000140436.1
Bcl2l1
BCL2-like 1
chr5_-_123865491 1.264 ENSMUST00000057145.5
Niacr1
niacin receptor 1
chr6_+_129350237 1.252 ENSMUST00000065289.4
Clec12a
C-type lectin domain family 12, member a
chr4_+_129960760 1.251 ENSMUST00000139884.1
1700003M07Rik
RIKEN cDNA 1700003M07 gene
chr5_-_65091584 1.246 ENSMUST00000043352.4
Tmem156
transmembrane protein 156
chr2_-_152830615 1.243 ENSMUST00000146380.1
ENSMUST00000134902.1
ENSMUST00000134357.1
ENSMUST00000109820.3
Bcl2l1



BCL2-like 1



chr11_+_96282648 1.233 ENSMUST00000168043.1
Hoxb8
homeobox B8
chr2_-_102451792 1.209 ENSMUST00000099678.3
Fjx1
four jointed box 1 (Drosophila)
chr8_-_70234401 1.150 ENSMUST00000019679.5
Armc6
armadillo repeat containing 6
chr11_-_96747405 1.135 ENSMUST00000180492.1
2010300F17Rik
RIKEN cDNA 2010300F17 gene
chr1_+_52008210 1.124 ENSMUST00000027277.5
Stat4
signal transducer and activator of transcription 4
chr7_+_25282179 1.112 ENSMUST00000163320.1
ENSMUST00000005578.6
Cic

capicua homolog (Drosophila)

chr11_+_98741805 1.097 ENSMUST00000064187.5
Thra
thyroid hormone receptor alpha
chr13_-_21810190 1.078 ENSMUST00000110469.1
ENSMUST00000091749.2
Hist1h2bq

histone cluster 1, H2bq

chr17_-_35164891 1.073 ENSMUST00000025253.5
Prrc2a
proline-rich coiled-coil 2A
chr2_+_91096744 1.065 ENSMUST00000132741.2
Spi1
spleen focus forming virus (SFFV) proviral integration oncogene
chr15_+_85017138 1.063 ENSMUST00000023070.5
Upk3a
uroplakin 3A
chr7_-_102477902 1.044 ENSMUST00000061482.5
Olfr543
olfactory receptor 543
chr9_+_74848437 1.011 ENSMUST00000161862.1
ENSMUST00000162089.1
ENSMUST00000160017.1
ENSMUST00000160950.1
Gm16551


Gm20649
predicted gene 16551


predicted gene 20649
chr6_+_122553799 0.996 ENSMUST00000043301.7
Aicda
activation-induced cytidine deaminase
chr17_-_46556158 0.972 ENSMUST00000015749.5
Srf
serum response factor
chr7_+_27486910 0.963 ENSMUST00000008528.7
Sertad1
SERTA domain containing 1
chr18_+_53551594 0.957 ENSMUST00000115398.1
Prdm6
PR domain containing 6
chr12_-_114060315 0.955 ENSMUST00000103469.2
Ighv14-3
immunoglobulin heavy variable V14-3
chr6_-_65144908 0.952 ENSMUST00000031982.4
Hpgds
hematopoietic prostaglandin D synthase
chr6_+_30568367 0.940 ENSMUST00000049251.5
Cpa4
carboxypeptidase A4
chr13_-_49309217 0.919 ENSMUST00000110087.2
Fgd3
FYVE, RhoGEF and PH domain containing 3
chrX_-_164250368 0.904 ENSMUST00000112263.1
Bmx
BMX non-receptor tyrosine kinase
chr8_+_70234613 0.886 ENSMUST00000145078.1
Sugp2
SURP and G patch domain containing 2
chr14_-_67715585 0.866 ENSMUST00000163100.1
ENSMUST00000132705.1
ENSMUST00000124045.1
Cdca2


cell division cycle associated 2


chr11_+_98741871 0.862 ENSMUST00000103139.4
Thra
thyroid hormone receptor alpha
chr16_+_17233560 0.861 ENSMUST00000090190.5
ENSMUST00000115698.2
Hic2

hypermethylated in cancer 2

chr1_+_12718496 0.859 ENSMUST00000088585.3
Sulf1
sulfatase 1
chr11_+_60469339 0.840 ENSMUST00000071880.2
ENSMUST00000081823.5
ENSMUST00000094135.2
Myo15


myosin XV


chr17_-_27133902 0.827 ENSMUST00000119227.1
ENSMUST00000025045.8
Uqcc2

ubiquinol-cytochrome c reductase complex assembly factor 2

chr4_-_137118135 0.802 ENSMUST00000154285.1
Gm13001
predicted gene 13001
chr6_-_142804390 0.800 ENSMUST00000111768.1
Gm766
predicted gene 766
chr4_-_88033328 0.794 ENSMUST00000078090.5
Mllt3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr8_+_31150307 0.769 ENSMUST00000098842.2
Tti2
TELO2 interacting protein 2
chr1_-_126830632 0.750 ENSMUST00000112583.1
ENSMUST00000094609.3
Nckap5

NCK-associated protein 5

chr11_+_51289920 0.739 ENSMUST00000102765.2
Col23a1
collagen, type XXIII, alpha 1
chr11_-_5837760 0.734 ENSMUST00000109837.1
Polm
polymerase (DNA directed), mu
chr2_-_71367749 0.710 ENSMUST00000151937.1
Slc25a12
solute carrier family 25 (mitochondrial carrier, Aralar), member 12
chr8_-_122678653 0.681 ENSMUST00000134045.1
Cbfa2t3
core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)
chr6_-_56369625 0.671 ENSMUST00000170774.1
ENSMUST00000168944.1
ENSMUST00000166890.1
Pde1c


phosphodiesterase 1C


chr7_+_141195047 0.670 ENSMUST00000047093.4
Lrrc56
leucine rich repeat containing 56
chr16_-_4880284 0.668 ENSMUST00000037843.6
Ubald1
UBA-like domain containing 1
chr1_+_75236439 0.666 ENSMUST00000082158.6
ENSMUST00000055223.7
Dnajb2

DnaJ (Hsp40) homolog, subfamily B, member 2

chr18_+_50051702 0.663 ENSMUST00000134348.1
ENSMUST00000153873.2
Tnfaip8

tumor necrosis factor, alpha-induced protein 8

chr17_+_47140942 0.662 ENSMUST00000077951.7
Trerf1
transcriptional regulating factor 1
chr7_+_122289297 0.662 ENSMUST00000064989.5
ENSMUST00000064921.4
Prkcb

protein kinase C, beta

chr11_-_98053415 0.658 ENSMUST00000017544.2
Stac2
SH3 and cysteine rich domain 2
chr2_+_74681991 0.649 ENSMUST00000142312.1
Hoxd11
homeobox D11
chr8_-_9771018 0.648 ENSMUST00000110969.3
Fam155a
family with sequence similarity 155, member A
chr19_+_41593363 0.641 ENSMUST00000099454.3
AI606181
expressed sequence AI606181
chr4_+_123183722 0.633 ENSMUST00000152194.1
Hpcal4
hippocalcin-like 4
chr19_+_53140430 0.621 ENSMUST00000111741.2
Add3
adducin 3 (gamma)
chr12_-_115964196 0.611 ENSMUST00000103550.2
Ighv1-83
immunoglobulin heavy variable 1-83
chr17_-_24533709 0.609 ENSMUST00000061764.7
Rab26
RAB26, member RAS oncogene family
chr7_+_82175156 0.581 ENSMUST00000180243.1
Sh3gl3
SH3-domain GRB2-like 3
chr7_-_28372494 0.574 ENSMUST00000119990.1
Plekhg2
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr5_-_122988533 0.574 ENSMUST00000086200.4
ENSMUST00000156474.1
Kdm2b

lysine (K)-specific demethylase 2B

chr17_+_27057288 0.572 ENSMUST00000049308.8
Itpr3
inositol 1,4,5-triphosphate receptor 3
chr14_+_62292475 0.554 ENSMUST00000166879.1
Rnaseh2b
ribonuclease H2, subunit B
chr4_-_64046925 0.547 ENSMUST00000107377.3
Tnc
tenascin C
chr14_+_79515618 0.540 ENSMUST00000110835.1
Elf1
E74-like factor 1
chrX_-_111531163 0.539 ENSMUST00000128819.1
Rps6ka6
ribosomal protein S6 kinase polypeptide 6
chr13_+_21787461 0.530 ENSMUST00000110473.2
ENSMUST00000102982.1
Hist1h2bp

histone cluster 1, H2bp

chr1_+_70725902 0.526 ENSMUST00000161937.1
ENSMUST00000162182.1
Vwc2l

von Willebrand factor C domain-containing protein 2-like

chr4_+_128654686 0.514 ENSMUST00000030588.6
ENSMUST00000136377.1
Phc2

polyhomeotic-like 2 (Drosophila)

chr13_+_83738874 0.508 ENSMUST00000052354.4
C130071C03Rik
RIKEN cDNA C130071C03 gene
chr18_-_80986578 0.504 ENSMUST00000057950.7
Sall3
sal-like 3 (Drosophila)
chr10_+_90071095 0.495 ENSMUST00000183109.1
Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chr19_-_40994133 0.478 ENSMUST00000117695.1
Blnk
B cell linker
chr12_-_115790884 0.476 ENSMUST00000081809.5
Ighv1-73
immunoglobulin heavy variable 1-73
chr16_-_89818338 0.464 ENSMUST00000164263.2
Tiam1
T cell lymphoma invasion and metastasis 1
chr1_+_70725715 0.464 ENSMUST00000053922.5
Vwc2l
von Willebrand factor C domain-containing protein 2-like
chr5_-_122989086 0.462 ENSMUST00000046073.9
Kdm2b
lysine (K)-specific demethylase 2B
chr5_+_53590215 0.459 ENSMUST00000037618.6
Rbpj
recombination signal binding protein for immunoglobulin kappa J region
chr5_-_122900267 0.456 ENSMUST00000031435.7
Kdm2b
lysine (K)-specific demethylase 2B
chrX_+_150594420 0.447 ENSMUST00000112713.2
Pfkfb1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr7_+_27591513 0.439 ENSMUST00000108344.2
Akt2
thymoma viral proto-oncogene 2
chr16_-_91728599 0.422 ENSMUST00000122254.1
Cryzl1
crystallin, zeta (quinone reductase)-like 1
chr13_-_23621090 0.411 ENSMUST00000091704.5
ENSMUST00000051091.3
Hist1h2be

histone cluster 1, H2be

chr4_+_104766308 0.407 ENSMUST00000031663.3
C8b
complement component 8, beta polypeptide
chr9_-_85327110 0.405 ENSMUST00000034802.8
Fam46a
family with sequence similarity 46, member A
chr3_+_76074270 0.404 ENSMUST00000038364.8
Fstl5
follistatin-like 5

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.2 GO:2000872 positive regulation of progesterone secretion(GO:2000872)
0.9 3.5 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.8 3.1 GO:0043973 histone H3-K4 acetylation(GO:0043973)
0.7 2.2 GO:2000040 regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.7 5.6 GO:0002326 B cell lineage commitment(GO:0002326)
0.7 2.1 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.7 2.0 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.6 2.5 GO:0046898 response to cycloheximide(GO:0046898)
0.6 4.6 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.5 2.0 GO:0060775 mediolateral intercalation(GO:0060031) planar cell polarity pathway involved in gastrula mediolateral intercalation(GO:0060775)
0.5 3.2 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.4 1.3 GO:1904170 regulation of bleb assembly(GO:1904170)
0.4 4.5 GO:0030916 otic vesicle formation(GO:0030916)
0.4 2.2 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.4 1.7 GO:0016062 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.4 6.7 GO:0006657 CDP-choline pathway(GO:0006657)
0.4 44.3 GO:0006334 nucleosome assembly(GO:0006334)
0.3 3.8 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.3 3.4 GO:0051025 negative regulation of immunoglobulin secretion(GO:0051025)
0.3 3.6 GO:0006337 nucleosome disassembly(GO:0006337)
0.3 0.9 GO:0060686 negative regulation of prostatic bud formation(GO:0060686)
0.3 3.9 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.3 1.1 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.3 1.1 GO:0060157 urinary bladder development(GO:0060157)
0.3 2.0 GO:2000138 positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.2 26.7 GO:0006342 chromatin silencing(GO:0006342)
0.2 1.0 GO:1900222 negative regulation of amyloid-beta clearance(GO:1900222)
0.2 1.7 GO:0035799 ureter maturation(GO:0035799)
0.2 0.7 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.2 1.5 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.2 4.6 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.2 1.5 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.2 1.9 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.2 0.4 GO:0060018 astrocyte fate commitment(GO:0060018)
0.2 2.7 GO:0046085 adenosine metabolic process(GO:0046085)
0.2 7.9 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.2 1.0 GO:1905937 negative regulation of germ cell proliferation(GO:1905937) negative regulation of male germ cell proliferation(GO:2000255)
0.2 0.5 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
0.2 1.5 GO:0006265 DNA topological change(GO:0006265)
0.2 2.3 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.2 0.7 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.2 7.7 GO:0006284 base-excision repair(GO:0006284)
0.2 3.8 GO:0019370 leukotriene biosynthetic process(GO:0019370)
0.2 0.5 GO:1900149 positive regulation of Schwann cell migration(GO:1900149)
0.2 6.2 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 1.9 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.1 0.3 GO:0060435 bronchiole development(GO:0060435)
0.1 1.9 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.1 2.7 GO:0021516 dorsal spinal cord development(GO:0021516)
0.1 1.5 GO:0070995 NADPH oxidation(GO:0070995)
0.1 0.3 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892)
0.1 0.7 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.1 0.2 GO:1903445 protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.1 3.7 GO:0031424 keratinization(GO:0031424)
0.1 0.6 GO:0050917 sensory perception of umami taste(GO:0050917)
0.1 2.2 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.1 1.7 GO:0060736 prostate gland growth(GO:0060736)
0.1 1.0 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.1 1.6 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1 0.7 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.1 1.5 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.1 3.5 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.1 0.2 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.1 1.6 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.1 0.2 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.1 0.7 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.1 0.9 GO:0001865 NK T cell differentiation(GO:0001865)
0.1 0.8 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1 0.3 GO:0072368 regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter(GO:0072368)
0.1 1.3 GO:0034501 protein localization to kinetochore(GO:0034501)
0.1 0.8 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 1.6 GO:0060065 uterus development(GO:0060065)
0.1 0.2 GO:0071600 otic vesicle morphogenesis(GO:0071600)
0.1 4.6 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 1.7 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.1 0.6 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.1 0.3 GO:0061589 calcium activated phosphatidylserine scrambling(GO:0061589)
0.1 2.5 GO:0060325 face morphogenesis(GO:0060325)
0.1 2.2 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.1 0.3 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.1 0.3 GO:2000210 positive regulation of anoikis(GO:2000210)
0.1 0.2 GO:0061075 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.0 0.4 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.7 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.5 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.0 0.1 GO:1900248 negative regulation of cytoplasmic translational elongation(GO:1900248)
0.0 0.2 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.5 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 1.3 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.0 1.2 GO:0010842 retina layer formation(GO:0010842)
0.0 0.1 GO:0070347 brown fat cell proliferation(GO:0070342) regulation of brown fat cell proliferation(GO:0070347)
0.0 0.6 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cytosol(GO:1902656)
0.0 0.7 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.5 GO:0021889 olfactory bulb interneuron differentiation(GO:0021889) olfactory bulb interneuron development(GO:0021891)
0.0 0.1 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.0 0.1 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.0 0.5 GO:0050858 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.4 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.6 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.4 GO:0035745 T-helper 2 cell cytokine production(GO:0035745)
0.0 0.9 GO:0035307 positive regulation of protein dephosphorylation(GO:0035307)
0.0 0.1 GO:0009624 response to nematode(GO:0009624)
0.0 0.4 GO:0030193 regulation of blood coagulation(GO:0030193) regulation of hemostasis(GO:1900046)
0.0 1.4 GO:0051591 response to cAMP(GO:0051591)
0.0 0.7 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.3 GO:0007369 formation of primary germ layer(GO:0001704) ectoderm formation(GO:0001705) endoderm formation(GO:0001706) mesoderm formation(GO:0001707) gastrulation(GO:0007369)
0.0 0.2 GO:0019532 oxalate transport(GO:0019532)
0.0 0.2 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.2 GO:0050857 positive regulation of antigen receptor-mediated signaling pathway(GO:0050857)
0.0 0.4 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.0 0.2 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.0 2.4 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.1 GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
0.0 0.7 GO:0048286 lung alveolus development(GO:0048286)
0.0 1.6 GO:0065004 protein-DNA complex assembly(GO:0065004)
0.0 1.5 GO:0007338 single fertilization(GO:0007338)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 7.7 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.6 47.6 GO:0000786 nucleosome(GO:0000786)
0.4 3.5 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.4 8.4 GO:0019814 immunoglobulin complex(GO:0019814)
0.3 1.3 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.3 1.1 GO:0120001 apical plasma membrane urothelial plaque(GO:0120001)
0.2 1.5 GO:0001651 dense fibrillar component(GO:0001651)
0.2 2.5 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.2 1.3 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 0.4 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.1 1.7 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 3.7 GO:0001533 cornified envelope(GO:0001533)
0.1 1.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 0.6 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.1 0.4 GO:0008623 CHRAC(GO:0008623)
0.1 0.2 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.1 1.9 GO:0070822 Sin3-type complex(GO:0070822)
0.1 1.5 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 1.5 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 0.7 GO:0005579 membrane attack complex(GO:0005579)
0.1 0.2 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.4 GO:0042382 paraspeckles(GO:0042382)
0.0 1.0 GO:0000178 exosome (RNase complex)(GO:0000178) exoribonuclease complex(GO:1905354)
0.0 0.3 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 1.7 GO:0097440 apical dendrite(GO:0097440)
0.0 0.5 GO:0097732 kinocilium(GO:0060091) 9+2 non-motile cilium(GO:0097732)
0.0 3.9 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 3.9 GO:0016605 PML body(GO:0016605)
0.0 1.9 GO:0031519 PcG protein complex(GO:0031519)
0.0 3.6 GO:0005604 basement membrane(GO:0005604)
0.0 1.1 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.6 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 1.9 GO:0005581 collagen trimer(GO:0005581)
0.0 0.3 GO:0042788 polysomal ribosome(GO:0042788)
0.0 2.9 GO:0043195 terminal bouton(GO:0043195)
0.0 0.8 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 6.4 GO:0016607 nuclear speck(GO:0016607)
0.0 0.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 1.3 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 2.1 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.0 0.8 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 1.7 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.5 GO:0005801 cis-Golgi network(GO:0005801)
0.0 2.5 GO:0005578 proteinaceous extracellular matrix(GO:0005578)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 7.9 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
1.3 6.7 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.9 3.8 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.8 7.7 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.7 5.6 GO:0070644 vitamin D response element binding(GO:0070644)
0.7 2.0 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
0.4 2.2 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.4 1.5 GO:0097100 supercoiled DNA binding(GO:0097100)
0.4 3.5 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.3 1.9 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.3 2.1 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.3 1.3 GO:0043515 kinetochore binding(GO:0043515)
0.3 3.1 GO:0030274 LIM domain binding(GO:0030274)
0.3 2.5 GO:0051434 BH3 domain binding(GO:0051434)
0.3 3.5 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.2 6.2 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.2 1.7 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.2 2.2 GO:0061133 endopeptidase activator activity(GO:0061133)
0.2 1.0 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.2 0.7 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.2 0.6 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.2 46.0 GO:0008301 DNA binding, bending(GO:0008301)
0.2 1.4 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.2 0.6 GO:0019002 GMP binding(GO:0019002)
0.2 0.9 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2 1.0 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 2.7 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 0.6 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 1.7 GO:0016918 retinal binding(GO:0016918)
0.1 1.3 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 0.7 GO:0035184 histone threonine kinase activity(GO:0035184)
0.1 1.5 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 0.3 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.1 5.1 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 1.5 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.1 0.7 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 3.8 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 1.1 GO:0051525 NFAT protein binding(GO:0051525)
0.1 0.8 GO:0070878 primary miRNA binding(GO:0070878)
0.1 4.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 0.6 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1 1.5 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 1.3 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 3.2 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 0.5 GO:0045545 syndecan binding(GO:0045545)
0.1 0.4 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 0.4 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.7 GO:0070628 proteasome binding(GO:0070628)
0.0 0.5 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.2 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.0 1.9 GO:0003785 actin monomer binding(GO:0003785)
0.0 3.2 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 0.2 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 3.4 GO:0019209 kinase activator activity(GO:0019209)
0.0 0.2 GO:0051373 FATZ binding(GO:0051373)
0.0 0.2 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.1 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.0 1.5 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 5.1 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 0.9 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 1.7 GO:0001540 amyloid-beta binding(GO:0001540)
0.0 0.5 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229) intracellular chloride channel activity(GO:0061778)
0.0 1.0 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.7 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.9 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.9 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.7 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 1.6 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.4 GO:0017091 AU-rich element binding(GO:0017091)
0.0 1.4 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.2 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.3 GO:0097602 cullin family protein binding(GO:0097602)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 6.1 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 4.4 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.1 2.5 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 4.9 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 9.0 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.1 0.3 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 3.2 PID_RAS_PATHWAY Regulation of Ras family activation
0.1 1.6 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 1.8 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.5 PID_EPHA2_FWD_PATHWAY EPHA2 forward signaling
0.0 1.4 PID_EPHB_FWD_PATHWAY EPHB forward signaling
0.0 4.5 PID_PDGFRB_PATHWAY PDGFR-beta signaling pathway
0.0 2.6 PID_BCR_5PATHWAY BCR signaling pathway
0.0 1.4 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 1.1 PID_IL27_PATHWAY IL27-mediated signaling events
0.0 1.9 NABA_COLLAGENS Genes encoding collagen proteins
0.0 0.7 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 1.5 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.0 3.3 PID_P53_DOWNSTREAM_PATHWAY Direct p53 effectors
0.0 0.6 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.5 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.0 0.9 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.7 PID_ERBB4_PATHWAY ErbB4 signaling events
0.0 0.7 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.9 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.0 1.5 WNT_SIGNALING Genes related to Wnt-mediated signal transduction

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 43.9 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
1.0 7.7 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.2 6.7 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.2 5.4 REACTOME_BASIGIN_INTERACTIONS Genes involved in Basigin interactions
0.2 2.7 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism
0.2 2.5 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.2 3.3 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 1.6 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 3.7 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 2.5 REACTOME_INFLAMMASOMES Genes involved in Inflammasomes
0.1 1.9 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 4.3 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.1 3.8 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.1 3.3 REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 1.3 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 1.3 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.0 0.7 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 1.7 REACTOME_METABOLISM_OF_STEROID_HORMONES_AND_VITAMINS_A_AND_D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 3.3 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 0.8 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 1.9 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 1.2 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.7 REACTOME_COMPLEMENT_CASCADE Genes involved in Complement cascade
0.0 1.9 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 1.9 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.2 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.5 REACTOME_RECYCLING_PATHWAY_OF_L1 Genes involved in Recycling pathway of L1
0.0 0.9 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 1.9 REACTOME_G_ALPHA_I_SIGNALLING_EVENTS Genes involved in G alpha (i) signalling events