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GSE58827: Dynamics of the Mouse Liver

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Results for Pou2f3

Z-value: 0.88

Motif logo

Transcription factors associated with Pou2f3

Gene Symbol Gene ID Gene Info
ENSMUSG00000032015.9 POU domain, class 2, transcription factor 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Pou2f3mm10_v2_chr9_-_43205755_432058850.298.8e-02Click!

Activity profile of Pou2f3 motif

Sorted Z-values of Pou2f3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_13733502 5.99 ENSMUST00000086148.6
sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 2
chr7_-_142656018 5.74 ENSMUST00000178921.1
insulin-like growth factor 2
chr1_+_40439767 5.38 ENSMUST00000173514.1
interleukin 1 receptor-like 1
chr11_+_87793470 5.03 ENSMUST00000020779.4
myeloperoxidase
chr17_+_25298389 4.98 ENSMUST00000037453.2
protease, serine, 34
chr1_+_40439627 4.92 ENSMUST00000097772.3
interleukin 1 receptor-like 1
chr12_-_114060315 4.19 ENSMUST00000103469.2
immunoglobulin heavy variable V14-3
chr7_-_13837410 3.99 ENSMUST00000108522.3
sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
chr10_+_79879614 3.87 ENSMUST00000006679.8
proteinase 3
chr2_-_121036750 3.73 ENSMUST00000023987.5
erythrocyte protein band 4.2
chr11_-_11970540 3.58 ENSMUST00000109653.1
growth factor receptor bound protein 10
chr10_-_75940633 3.36 ENSMUST00000059658.4
predicted gene 867
chr17_+_40811089 3.29 ENSMUST00000024721.7
Rhesus blood group-associated A glycoprotein
chr11_-_69605829 3.12 ENSMUST00000047889.6
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr9_-_39604124 3.06 ENSMUST00000042485.4
ENSMUST00000141370.1
expressed sequence AW551984
chr17_-_43502773 2.99 ENSMUST00000024707.8
ENSMUST00000117137.1
meprin 1 alpha
chr7_-_14123042 2.86 ENSMUST00000098809.2
sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 3
chrX_+_56454871 2.81 ENSMUST00000039374.2
ENSMUST00000101553.2
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
chr12_-_99883429 2.71 ENSMUST00000046485.3
EF-hand calcium binding domain 11
chr16_-_42340595 2.61 ENSMUST00000102817.4
growth associated protein 43
chr8_-_46211284 2.55 ENSMUST00000034049.4
solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4
chr12_-_115964196 2.51 ENSMUST00000103550.2
immunoglobulin heavy variable 1-83
chr16_+_32186192 2.43 ENSMUST00000099990.3
brain expressed gene 6
chr10_-_80421847 2.41 ENSMUST00000156244.1
transcription factor 3
chr11_+_69045640 2.21 ENSMUST00000108666.1
ENSMUST00000021277.5
aurora kinase B
chr12_+_108605757 2.20 ENSMUST00000109854.2
Ena-vasodilator stimulated phosphoprotein
chr7_+_35449035 2.18 ENSMUST00000118969.1
ENSMUST00000118383.1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 9
chr12_-_115790884 2.18 ENSMUST00000081809.5
immunoglobulin heavy variable 1-73
chr17_+_56303321 2.13 ENSMUST00000001258.8
ubiquitin-like, containing PHD and RING finger domains, 1
chr16_+_17146937 2.01 ENSMUST00000115706.1
ENSMUST00000069064.4
YdjC homolog (bacterial)
chr17_+_56303396 2.00 ENSMUST00000113038.1
ubiquitin-like, containing PHD and RING finger domains, 1
chr4_-_134012381 1.98 ENSMUST00000176113.1
lin-28 homolog A (C. elegans)
chr6_-_41314700 1.92 ENSMUST00000064324.5
trypsin 5
chr7_+_35449154 1.82 ENSMUST00000032703.9
solute carrier family 7 (cationic amino acid transporter, y+ system), member 9
chr9_+_95637601 1.79 ENSMUST00000015498.8
procollagen C-endopeptidase enhancer 2
chr10_-_29699379 1.69 ENSMUST00000092620.4
predicted pseudogene 10275
chrX_-_36991724 1.64 ENSMUST00000152291.1
septin 6
chr7_-_28372494 1.63 ENSMUST00000119990.1
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr6_+_41521782 1.62 ENSMUST00000070380.4
protease, serine, 2
chr7_-_28372597 1.57 ENSMUST00000144700.1
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr9_+_36832684 1.53 ENSMUST00000034630.8
fasciculation and elongation protein zeta 1 (zygin I)
chr7_+_140218258 1.52 ENSMUST00000084460.6
CD163 molecule-like 1
chr16_-_75909272 1.52 ENSMUST00000114239.2
SAM domain, SH3 domain and nuclear localization signals, 1
chr11_+_3989924 1.51 ENSMUST00000109981.1
galactose-3-O-sulfotransferase 1
chr13_-_90905321 1.50 ENSMUST00000109541.3
ATPase, H+ transporting, lysosomal accessory protein 1-like
chr11_+_96929367 1.48 ENSMUST00000062172.5
proline rich 15-like
chr1_-_23909687 1.48 ENSMUST00000129254.1
small ArfGAP 1
chr10_+_37139558 1.44 ENSMUST00000062667.3
RIKEN cDNA 5930403N24 gene
chrX_-_150814265 1.38 ENSMUST00000026302.6
ENSMUST00000129768.1
ENSMUST00000112699.2
melanoma antigen, family D, 2
chr10_+_128015157 1.34 ENSMUST00000178041.1
ENSMUST00000026461.7
DNA primase, p49 subunit
chr12_-_112929415 1.34 ENSMUST00000075827.3
jagged 2
chr13_-_21780616 1.33 ENSMUST00000080511.2
histone cluster 1, H1b
chr4_+_134102581 1.32 ENSMUST00000074690.4
ENSMUST00000070246.2
ENSMUST00000156750.1
UBX domain protein 11
chr12_-_118198917 1.31 ENSMUST00000084806.6
dynein, axonemal, heavy chain 11
chr17_+_25016343 1.31 ENSMUST00000024983.5
intraflagellar transport 140
chrX_-_23266751 1.30 ENSMUST00000115316.2
kelch-like 13
chr13_-_100316616 1.29 ENSMUST00000042220.2
NLR family, apoptosis inhibitory protein 6
chr10_+_128238034 1.23 ENSMUST00000105245.2
timeless circadian clock 1
chr16_+_44347121 1.22 ENSMUST00000050897.6
spindle and centriole associated protein 1
chr1_-_38898084 1.21 ENSMUST00000027249.6
carbohydrate sulfotransferase 10
chr12_-_11265768 1.19 ENSMUST00000166117.1
Gen homolog 1, endonuclease (Drosophila)
chr19_+_40659770 1.17 ENSMUST00000112231.2
ENSMUST00000127828.1
ectonucleoside triphosphate diphosphohydrolase 1
chr19_-_36919606 1.16 ENSMUST00000057337.7
fibroblast growth factor binding protein 3
chr6_-_115853346 1.14 ENSMUST00000032469.6
methyl-CpG binding domain protein 4
chr6_+_34476207 1.14 ENSMUST00000045372.5
ENSMUST00000138668.1
ENSMUST00000139067.1
2,3-bisphosphoglycerate mutase
chr1_-_79440039 1.13 ENSMUST00000049972.4
secretogranin II
chr1_+_51987139 1.12 ENSMUST00000168302.1
signal transducer and activator of transcription 4
chr17_+_23726336 1.11 ENSMUST00000024701.7
protein kinase, membrane associated tyrosine/threonine 1
chr16_-_45492962 1.11 ENSMUST00000114585.2
predicted gene 609
chr6_-_56901870 1.11 ENSMUST00000101367.2
5'-nucleotidase, cytosolic III
chr17_+_80307396 1.09 ENSMUST00000068175.5
Rho guanine nucleotide exchange factor (GEF) 33
chr5_-_122900267 1.08 ENSMUST00000031435.7
lysine (K)-specific demethylase 2B
chr4_+_108479081 1.08 ENSMUST00000155068.1
zinc finger, CCHC domain containing 11
chr16_-_19883873 1.06 ENSMUST00000100083.3
RIKEN cDNA A930003A15 gene
chr9_+_124102110 1.03 ENSMUST00000168841.1
ENSMUST00000055918.6
chemokine (C-C motif) receptor 2
chr11_+_96929260 1.02 ENSMUST00000054311.5
ENSMUST00000107636.3
proline rich 15-like
chr15_-_36879816 1.01 ENSMUST00000100713.2
predicted gene 10384
chr13_-_100246323 1.01 ENSMUST00000049789.2
NLR family, apoptosis inhibitory protein 5
chr10_-_51631458 0.99 ENSMUST00000020062.3
G protein-coupled receptor, family C, group 6, member A
chr9_-_26806384 0.97 ENSMUST00000162702.1
ENSMUST00000040398.7
ENSMUST00000066560.6
galactosidase, beta 1-like 2
chr13_-_22219820 0.97 ENSMUST00000057516.1
vomeronasal 1 receptor 193
chr3_+_87376381 0.94 ENSMUST00000163661.1
ENSMUST00000072480.2
ENSMUST00000167200.1
Fc receptor-like 1
chr17_+_25016068 0.94 ENSMUST00000137386.1
intraflagellar transport 140
chr2_+_22895482 0.92 ENSMUST00000053729.7
prenyl (solanesyl) diphosphate synthase, subunit 1
chr2_-_152830266 0.92 ENSMUST00000140436.1
BCL2-like 1
chr3_+_68572245 0.92 ENSMUST00000170788.2
schwannomin interacting protein 1
chr15_+_80133114 0.92 ENSMUST00000023050.7
TGF-beta activated kinase 1/MAP3K7 binding protein 1
chr9_-_90255927 0.92 ENSMUST00000144646.1
TBC1 domain family, member 2B
chr13_-_23991158 0.91 ENSMUST00000021770.7
secretagogin, EF-hand calcium binding protein
chr12_-_69582985 0.91 ENSMUST00000058639.9
methyltransferase like 21D
chr17_+_33629078 0.90 ENSMUST00000166627.1
ENSMUST00000073570.5
ENSMUST00000170225.1
zinc finger protein 414
chr1_+_87403705 0.90 ENSMUST00000172736.1
GRB10 interacting GYF protein 2
chr6_-_129740484 0.88 ENSMUST00000050385.5
killer cell lectin-like receptor family I member 2
chr3_+_51559973 0.87 ENSMUST00000180404.1
RIKEN cDNA 5031434O11 gene
chr13_-_106847267 0.86 ENSMUST00000057427.4
leucine rich repeat containing 70
chr2_+_86007778 0.85 ENSMUST00000062166.1
olfactory receptor 1032
chr9_+_124101944 0.85 ENSMUST00000171719.1
chemokine (C-C motif) receptor 2
chr2_+_164074122 0.85 ENSMUST00000018353.7
serine/threonine kinase 4
chr16_-_19983005 0.85 ENSMUST00000058839.8
kelch-like 6
chrX_+_71555918 0.85 ENSMUST00000072699.6
ENSMUST00000114582.2
ENSMUST00000015361.4
ENSMUST00000088874.3
high mobility group box 3
chr18_+_37504264 0.84 ENSMUST00000052179.6
protocadherin beta 20
chr15_-_42676967 0.83 ENSMUST00000022921.5
angiopoietin 1
chr17_-_50094277 0.82 ENSMUST00000113195.1
raftlin lipid raft linker 1
chr11_-_69758630 0.80 ENSMUST00000058470.9
polymerase (RNA) II (DNA directed) polypeptide A
chr9_+_78615501 0.80 ENSMUST00000093812.4
CD109 antigen
chr14_+_26122609 0.78 ENSMUST00000100810.6
doubl homeobox B-like 2
chr6_-_16898441 0.77 ENSMUST00000031533.7
transcription factor EC
chr16_-_19515634 0.77 ENSMUST00000054606.1
olfactory receptor 167
chr2_+_130277157 0.74 ENSMUST00000028890.8
ENSMUST00000159373.1
NOP56 ribonucleoprotein
chr4_+_149104130 0.74 ENSMUST00000103216.3
ENSMUST00000030816.3
DNA fragmentation factor, alpha subunit
chr9_+_51280295 0.73 ENSMUST00000050829.1
RIKEN cDNA 2010007H06 gene
chr16_-_29946499 0.72 ENSMUST00000181968.1
predicted gene, 26569
chrX_+_151522352 0.72 ENSMUST00000148622.1
PHD finger protein 8
chr6_-_99044414 0.71 ENSMUST00000177507.1
ENSMUST00000123992.1
forkhead box P1
chr7_-_28372233 0.70 ENSMUST00000094644.4
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr3_+_4211716 0.69 ENSMUST00000170943.1
predicted gene 8775
chr10_-_44458687 0.68 ENSMUST00000105490.2
PR domain containing 1, with ZNF domain
chr4_-_88676924 0.68 ENSMUST00000105148.1
predicted gene 13280
chrM_+_11734 0.64 ENSMUST00000082418.1
mitochondrially encoded NADH dehydrogenase 5
chrX_+_75382384 0.64 ENSMUST00000033541.4
FUN14 domain containing 2
chrX_+_96456362 0.64 ENSMUST00000079322.5
ENSMUST00000113838.1
hephaestin
chr16_+_18498768 0.64 ENSMUST00000167778.1
ENSMUST00000139625.1
ENSMUST00000149035.1
ENSMUST00000090086.4
ENSMUST00000115601.1
ENSMUST00000147739.1
ENSMUST00000146673.1
guanine nucleotide binding protein (G protein), beta polypeptide 1-like
predicted gene 16314
chr8_+_104250925 0.62 ENSMUST00000098464.4
chemokine-like factor
chr15_-_75841907 0.62 ENSMUST00000100538.2
zinc finger CCCH type containing 3
chr2_-_122611238 0.62 ENSMUST00000028624.8
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr15_-_78773452 0.61 ENSMUST00000018313.5
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr10_-_44458715 0.61 ENSMUST00000039174.4
PR domain containing 1, with ZNF domain
chr13_+_83573577 0.61 ENSMUST00000185052.1
myocyte enhancer factor 2C
chr2_-_152830615 0.61 ENSMUST00000146380.1
ENSMUST00000134902.1
ENSMUST00000134357.1
ENSMUST00000109820.3
BCL2-like 1
chr14_+_75284343 0.59 ENSMUST00000022577.5
zinc finger CCCH type containing 13
chrX_+_134059137 0.58 ENSMUST00000113287.1
ENSMUST00000033609.2
ENSMUST00000113286.1
cleavage stimulation factor, 3' pre-RNA subunit 2
chr2_-_73660401 0.58 ENSMUST00000102677.4
chimerin (chimaerin) 1
chr11_+_62847111 0.58 ENSMUST00000150989.1
ENSMUST00000176577.1
F-box and WD-40 domain protein 10
chr3_-_17230976 0.57 ENSMUST00000177874.1
predicted gene 5283
chrX_+_56786527 0.57 ENSMUST00000144600.1
four and a half LIM domains 1
chr12_+_30911659 0.56 ENSMUST00000020997.8
ENSMUST00000110880.2
Sh3 domain YSC-like 1
chr7_-_113347273 0.56 ENSMUST00000117577.1
BTB (POZ) domain containing 10
chr10_-_128525859 0.55 ENSMUST00000026427.6
extended synaptotagmin-like protein 1
chr2_-_175131864 0.55 ENSMUST00000108929.2
predicted gene 14399
chr19_-_45998479 0.55 ENSMUST00000045396.7
RIKEN cDNA 9130011E15 gene
chr14_+_32833955 0.54 ENSMUST00000104926.2
family with sequence similarity 170, member B
chr12_+_38780284 0.54 ENSMUST00000162563.1
ENSMUST00000161164.1
ENSMUST00000160996.1
ets variant gene 1
chr7_-_64392214 0.54 ENSMUST00000032735.5
M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)
chr2_-_72986716 0.53 ENSMUST00000112062.1
predicted gene 11084
chr16_+_16870829 0.52 ENSMUST00000131063.1
topoisomerase (DNA) III beta
chr3_-_63851251 0.52 ENSMUST00000162269.2
ENSMUST00000159676.2
ENSMUST00000175947.1
phospholipase C, eta 1
chr5_-_69590783 0.51 ENSMUST00000173927.1
glucosamine-6-phosphate deaminase 2
chr12_+_38781093 0.51 ENSMUST00000161513.1
ets variant gene 1
chr6_+_125215551 0.50 ENSMUST00000032487.7
ENSMUST00000100942.2
ENSMUST00000063588.8
vesicle-associated membrane protein 1
chr5_+_15934685 0.49 ENSMUST00000078272.6
ENSMUST00000180204.1
ENSMUST00000167946.2
ENSMUST00000101581.3
ENSMUST00000039370.7
calcium channel, voltage-dependent, alpha2/delta subunit 1
chr4_-_147642496 0.48 ENSMUST00000133006.1
ENSMUST00000037565.7
ENSMUST00000105720.1
RIKEN cDNA 2610305D13 gene
chr9_+_13619990 0.48 ENSMUST00000159294.1
mastermind like 2 (Drosophila)
chr2_+_78051155 0.48 ENSMUST00000145972.1
RIKEN cDNA 4930440I19 gene
chr3_+_94643112 0.48 ENSMUST00000107276.1
predicted gene 10972
chr7_-_4445181 0.47 ENSMUST00000138798.1
retinol dehydrogenase 13 (all-trans and 9-cis)
chr17_-_70998010 0.47 ENSMUST00000024846.6
myosin, light chain 12A, regulatory, non-sarcomeric
chr2_+_28192971 0.47 ENSMUST00000113920.1
olfactomedin 1
chr7_+_135268579 0.46 ENSMUST00000097983.3
neuropeptide S
chr8_+_21565368 0.46 ENSMUST00000084040.2
predicted gene 14850
chr5_+_92925400 0.45 ENSMUST00000172706.1
shroom family member 3
chr14_+_52110939 0.45 ENSMUST00000111600.4
retinitis pigmentosa GTPase regulator interacting protein 1
chr6_+_129350237 0.45 ENSMUST00000065289.4
C-type lectin domain family 12, member a
chr4_-_82850721 0.44 ENSMUST00000139401.1
zinc finger, DHHC domain containing 21
chr17_-_24073479 0.44 ENSMUST00000017090.5
potassium channel tetramerisation domain containing 5
chr17_-_70924958 0.44 ENSMUST00000180468.1
predicted gene, 26510
chr9_-_58313189 0.43 ENSMUST00000061799.8
lysyl oxidase-like 1
chr13_-_60936550 0.43 ENSMUST00000021880.9
cytotoxic T lymphocyte-associated protein 2 alpha
chr4_+_147150494 0.42 ENSMUST00000151022.1
predicted gene 13139
chr2_+_28193093 0.42 ENSMUST00000100244.3
olfactomedin 1
chr11_-_103017167 0.42 ENSMUST00000021313.2
dephospho-CoA kinase domain containing
chr12_+_38780817 0.41 ENSMUST00000160856.1
ets variant gene 1
chr4_+_148448605 0.40 ENSMUST00000103221.3
ENSMUST00000057580.7
mechanistic target of rapamycin (serine/threonine kinase)
chr16_-_59269665 0.40 ENSMUST00000099656.1
olfactory receptor 201
chr1_+_66321708 0.40 ENSMUST00000114013.1
microtubule-associated protein 2
chr15_+_58510037 0.40 ENSMUST00000161028.1
fer-1-like 6 (C. elegans)
chr12_+_98268626 0.40 ENSMUST00000075072.4
G-protein coupled receptor 65
chr15_+_94629148 0.40 ENSMUST00000080141.4
transmembrane protein 117
chr14_+_50392758 0.39 ENSMUST00000058965.3
olfactory receptor 736
chr3_+_10366903 0.39 ENSMUST00000029049.5
charged multivesicular body protein 4C
chr9_+_64121501 0.38 ENSMUST00000118215.1
lactase-like
chr10_+_26229707 0.38 ENSMUST00000060716.5
ENSMUST00000164660.1
sterile alpha motif domain containing 3
chr14_-_75754475 0.38 ENSMUST00000049168.7
component of oligomeric golgi complex 3
chr2_+_25180737 0.38 ENSMUST00000104999.2
Notch-regulated ankyrin repeat protein
chr3_+_51559757 0.38 ENSMUST00000180616.1
RIKEN cDNA 5031434O11 gene
chr18_-_88927447 0.37 ENSMUST00000147313.1
suppressor of cytokine signaling 6
chr7_-_45434590 0.37 ENSMUST00000107771.3
ENSMUST00000141761.1
RuvB-like protein 2
chr2_+_112379204 0.36 ENSMUST00000028552.3
katanin p80 subunit B like 1
chr17_-_6449571 0.36 ENSMUST00000180035.1
transmembrane protein 181B, pseudogene
chr1_+_171840607 0.35 ENSMUST00000136479.1
ENSMUST00000042302.6
CD84 antigen
chr3_-_130709419 0.35 ENSMUST00000043937.7
oligosaccharyltransferase complex subunit
chrX_+_107149580 0.35 ENSMUST00000137107.1
ENSMUST00000067249.2
RIKEN cDNA A630033H20 gene
chr9_-_62026788 0.34 ENSMUST00000034817.4
progestin and adipoQ receptor family member V
chr18_+_78349754 0.34 ENSMUST00000164064.1
predicted gene 6133
chr11_-_4440745 0.34 ENSMUST00000109948.1
HORMA domain containing 2
chr5_-_108795352 0.34 ENSMUST00000004943.1
transmembrane emp24 protein transport domain containing
chr3_+_53845086 0.34 ENSMUST00000108014.1
predicted gene 10985
chr10_+_76468866 0.33 ENSMUST00000170795.1
minichromosome maintenance deficient 3 (S. cerevisiae) associated protein
chr6_-_57844493 0.33 ENSMUST00000081186.3
vomeronasal 1 receptor 21
chr3_+_136670076 0.33 ENSMUST00000070198.7
protein phosphatase 3, catalytic subunit, alpha isoform
chr11_+_62847062 0.33 ENSMUST00000036085.4
F-box and WD-40 domain protein 10

Network of associatons between targets according to the STRING database.

First level regulatory network of Pou2f3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.0 GO:0002148 hypochlorous acid metabolic process(GO:0002148) hypochlorous acid biosynthetic process(GO:0002149)
1.3 4.0 GO:0015811 L-cystine transport(GO:0015811)
1.1 3.3 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.9 10.3 GO:0002826 negative regulation of T-helper 1 type immune response(GO:0002826)
0.8 2.5 GO:0015866 ADP transport(GO:0015866)
0.8 3.1 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.8 3.9 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.7 2.2 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.7 5.7 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.6 1.9 GO:0090265 immune complex clearance by monocytes and macrophages(GO:0002436) astrocyte chemotaxis(GO:0035700) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) positive regulation of immune complex clearance by monocytes and macrophages(GO:0090265) negative regulation of eosinophil activation(GO:1902567) positive regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000451) regulation of astrocyte chemotaxis(GO:2000458)
0.4 1.3 GO:0033082 regulation of extrathymic T cell differentiation(GO:0033082)
0.4 5.0 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.4 1.2 GO:1904976 response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976)
0.4 1.5 GO:0046898 response to cycloheximide(GO:0046898)
0.3 3.1 GO:0010587 miRNA catabolic process(GO:0010587)
0.3 1.3 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.3 3.6 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719)
0.3 2.4 GO:0002326 B cell lineage commitment(GO:0002326)
0.3 2.6 GO:0016198 axon choice point recognition(GO:0016198)
0.3 0.8 GO:0030210 heparin biosynthetic process(GO:0030210)
0.3 4.1 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.2 0.7 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.2 1.1 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.2 0.7 GO:0032685 negative regulation of granulocyte macrophage colony-stimulating factor production(GO:0032685)
0.2 3.1 GO:0060923 cardiac muscle cell fate commitment(GO:0060923)
0.2 1.1 GO:0021993 initiation of neural tube closure(GO:0021993)
0.2 8.9 GO:0006910 phagocytosis, recognition(GO:0006910)
0.2 0.8 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.2 0.6 GO:0006601 creatine biosynthetic process(GO:0006601)
0.2 0.6 GO:0007521 muscle cell fate determination(GO:0007521)
0.2 4.0 GO:0051923 sulfation(GO:0051923)
0.2 1.3 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.2 2.5 GO:0070269 pyroptosis(GO:0070269)
0.2 1.4 GO:0070294 renal sodium ion absorption(GO:0070294)
0.2 2.2 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.2 0.8 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.2 1.5 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.2 1.2 GO:2001170 negative regulation of ATP biosynthetic process(GO:2001170)
0.2 2.2 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.1 1.3 GO:0003356 regulation of cilium beat frequency(GO:0003356)
0.1 1.2 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.1 0.4 GO:1990705 T-helper 1 cell lineage commitment(GO:0002296) cholangiocyte proliferation(GO:1990705)
0.1 0.8 GO:0072675 osteoclast fusion(GO:0072675)
0.1 1.2 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.1 0.4 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
0.1 0.5 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.1 0.4 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.1 0.8 GO:0032596 protein transport into membrane raft(GO:0032596)
0.1 0.5 GO:0010841 positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841)
0.1 0.3 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.1 1.5 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.1 0.5 GO:0080154 regulation of fertilization(GO:0080154)
0.1 1.1 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.1 1.6 GO:0031000 response to caffeine(GO:0031000)
0.1 1.5 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 0.4 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.1 0.4 GO:0071899 regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
0.1 0.3 GO:0019389 glucuronoside metabolic process(GO:0019389)
0.1 0.7 GO:0006265 DNA topological change(GO:0006265)
0.1 0.7 GO:1900118 negative regulation of execution phase of apoptosis(GO:1900118)
0.1 1.1 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 1.1 GO:2001223 negative regulation of neuron migration(GO:2001223)
0.1 0.2 GO:0010579 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.1 0.7 GO:0061470 interleukin-21 production(GO:0032625) T follicular helper cell differentiation(GO:0061470) interleukin-21 secretion(GO:0072619)
0.1 0.9 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 0.6 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.1 0.5 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.3 GO:0006203 dGTP catabolic process(GO:0006203)
0.1 0.3 GO:0051684 maintenance of Golgi location(GO:0051684)
0.1 1.7 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.1 0.8 GO:0002467 germinal center formation(GO:0002467)
0.1 1.2 GO:0046599 regulation of centriole replication(GO:0046599)
0.1 0.3 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.1 0.6 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 0.5 GO:0009644 response to high light intensity(GO:0009644)
0.1 1.5 GO:0050869 negative regulation of B cell activation(GO:0050869)
0.0 0.3 GO:0030910 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0 1.1 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.2 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.0 0.2 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.4 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.8 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.0 0.4 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.4 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.9 GO:0008210 luteinization(GO:0001553) estrogen metabolic process(GO:0008210)
0.0 0.3 GO:0043201 response to leucine(GO:0043201) cellular response to leucine(GO:0071233)
0.0 0.9 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.0 1.1 GO:0019236 response to pheromone(GO:0019236)
0.0 1.2 GO:0007616 long-term memory(GO:0007616)
0.0 1.5 GO:0033120 positive regulation of RNA splicing(GO:0033120)
0.0 0.1 GO:0061073 ciliary body morphogenesis(GO:0061073) Notch signaling involved in heart development(GO:0061314)
0.0 5.5 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.6 GO:1900027 regulation of ruffle assembly(GO:1900027)
0.0 0.5 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.4 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.2 GO:0051177 meiotic sister chromatid cohesion(GO:0051177)
0.0 0.1 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.2 GO:0045945 positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.0 0.7 GO:0000154 rRNA modification(GO:0000154)
0.0 0.6 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.0 0.3 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 1.6 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.1 GO:0032289 central nervous system myelin formation(GO:0032289)
0.0 0.4 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.0 0.6 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 0.2 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.3 GO:0042119 neutrophil activation(GO:0042119)
0.0 0.2 GO:0051601 exocyst localization(GO:0051601)
0.0 0.6 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.2 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.6 GO:0035176 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.0 0.9 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 1.3 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.4 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 1.3 GO:0000910 cytokinesis(GO:0000910)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0005940 septin ring(GO:0005940)
0.5 8.9 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.4 2.2 GO:0032133 chromosome passenger complex(GO:0032133)
0.4 2.5 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.3 3.1 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.3 5.0 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.3 1.3 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.2 2.2 GO:0030991 intraciliary transport particle A(GO:0030991)
0.2 0.5 GO:0034457 Mpp10 complex(GO:0034457)
0.2 0.5 GO:0070820 tertiary granule(GO:0070820)
0.2 0.5 GO:0071920 cleavage body(GO:0071920)
0.1 1.5 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 2.6 GO:0031527 filopodium membrane(GO:0031527)
0.1 0.7 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 5.3 GO:0000791 euchromatin(GO:0000791)
0.1 0.5 GO:0002081 outer acrosomal membrane(GO:0002081)
0.1 0.2 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.1 2.4 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 0.2 GO:0005713 recombination nodule(GO:0005713)
0.1 0.2 GO:0034687 integrin alphaL-beta2 complex(GO:0034687)
0.1 0.9 GO:1990635 proximal dendrite(GO:1990635)
0.1 1.0 GO:0031045 dense core granule(GO:0031045)
0.1 0.3 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.5 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.4 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.2 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 16.2 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.4 GO:0031931 TORC1 complex(GO:0031931)
0.0 1.3 GO:0000786 nucleosome(GO:0000786)
0.0 0.6 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 2.0 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.4 GO:0090543 Flemming body(GO:0090543)
0.0 0.4 GO:0017119 Golgi transport complex(GO:0017119)
0.0 2.9 GO:0031526 brush border membrane(GO:0031526)
0.0 0.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.5 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.6 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.2 GO:0097422 tubular endosome(GO:0097422)
0.0 0.4 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.9 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)
0.0 1.3 GO:0030286 dynein complex(GO:0030286)
0.0 0.3 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.1 GO:0071817 MMXD complex(GO:0071817)
0.0 0.1 GO:0005869 dynactin complex(GO:0005869)
0.0 1.2 GO:0005814 centriole(GO:0005814)
0.0 0.5 GO:0016460 myosin II complex(GO:0016460)
0.0 2.1 GO:0031012 extracellular matrix(GO:0031012)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 10.3 GO:0002113 interleukin-33 binding(GO:0002113)
1.3 4.0 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
1.0 6.8 GO:0004027 alcohol sulfotransferase activity(GO:0004027)
0.7 4.1 GO:0031493 nucleosomal histone binding(GO:0031493)
0.6 1.9 GO:0035717 chemokine (C-C motif) ligand 7 binding(GO:0035717)
0.4 1.1 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.4 1.5 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
0.4 8.9 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.3 2.6 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.3 2.4 GO:0070644 vitamin D response element binding(GO:0070644)
0.3 1.1 GO:0000700 mismatch base pair DNA N-glycosylase activity(GO:0000700)
0.3 3.1 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.2 0.7 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.2 0.9 GO:0000010 trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347)
0.2 2.5 GO:0005347 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.2 0.6 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.2 0.9 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.2 3.3 GO:0022842 leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
0.2 0.5 GO:0050429 calcium-dependent phospholipase C activity(GO:0050429)
0.2 2.2 GO:0005522 profilin binding(GO:0005522)
0.2 2.0 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.2 9.6 GO:0005158 insulin receptor binding(GO:0005158)
0.2 1.0 GO:0004565 beta-galactosidase activity(GO:0004565)
0.2 1.5 GO:0051434 BH3 domain binding(GO:0051434)
0.1 1.2 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1 1.2 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
0.1 0.7 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.1 0.4 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.1 0.4 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.1 7.2 GO:0008146 sulfotransferase activity(GO:0008146)
0.1 0.4 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
0.1 1.9 GO:0035174 histone serine kinase activity(GO:0035174)
0.1 0.5 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.1 5.0 GO:0004601 peroxidase activity(GO:0004601)
0.1 0.8 GO:0001055 RNA polymerase II activity(GO:0001055)
0.1 0.3 GO:0070052 collagen V binding(GO:0070052)
0.1 1.9 GO:0005550 pheromone binding(GO:0005550)
0.1 0.3 GO:0019767 IgE receptor activity(GO:0019767)
0.1 0.2 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.1 1.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 0.3 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.1 0.4 GO:0008422 beta-glucosidase activity(GO:0008422)
0.1 0.5 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.1 0.4 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1 1.1 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 0.2 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.1 0.9 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.1 0.4 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.1 2.3 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.3 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 1.3 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.1 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.0 0.4 GO:0050733 RS domain binding(GO:0050733)
0.0 0.2 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.0 1.1 GO:0042056 chemoattractant activity(GO:0042056)
0.0 10.1 GO:0008236 serine-type peptidase activity(GO:0008236)
0.0 0.6 GO:0035198 miRNA binding(GO:0035198)
0.0 0.6 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 1.5 GO:0005112 Notch binding(GO:0005112)
0.0 1.8 GO:0016504 peptidase activator activity(GO:0016504)
0.0 1.2 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.9 GO:0070064 proline-rich region binding(GO:0070064)
0.0 4.8 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.2 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.8 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 1.3 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 1.5 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.4 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 2.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.9 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 0.2 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.9 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.6 GO:0008198 ferrous iron binding(GO:0008198)
0.0 0.2 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.7 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.6 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.0 0.4 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.2 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.6 GO:0008009 chemokine activity(GO:0008009)
0.0 0.4 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.6 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.3 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.1 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.0 0.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.1 GO:0030620 U2 snRNA binding(GO:0030620)
0.0 0.4 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 1.0 GO:0030276 clathrin binding(GO:0030276)
0.0 0.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.2 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.5 GO:0005484 SNAP receptor activity(GO:0005484)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.9 PID IL23 PATHWAY IL23-mediated signaling events
0.1 3.9 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 2.6 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 3.6 PID IGF1 PATHWAY IGF1 pathway
0.1 1.5 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 5.7 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 3.5 PID AURORA B PATHWAY Aurora B signaling
0.1 1.2 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 5.9 PID CMYB PATHWAY C-MYB transcription factor network
0.0 3.7 PID E2F PATHWAY E2F transcription factor network
0.0 0.7 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.8 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.4 PID MYC PATHWAY C-MYC pathway
0.0 1.3 PID P73PATHWAY p73 transcription factor network
0.0 0.6 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.4 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 3.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.5 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.3 PID ATF2 PATHWAY ATF-2 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.5 REACTOME DEFENSINS Genes involved in Defensins
0.3 4.0 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.3 5.7 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2 7.1 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.2 3.6 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.2 0.9 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1 2.1 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 1.3 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1 1.1 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1 1.5 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 2.9 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 2.2 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 1.4 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.1 3.0 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 1.1 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 1.1 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.1 1.1 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 2.5 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.8 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 1.0 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.5 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.6 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.5 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 1.4 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 2.8 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 2.2 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 0.8 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.6 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 2.0 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.4 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.4 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.4 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.4 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.4 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.4 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.2 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing