Motif ID: Prop1

Z-value: 1.168


Transcription factors associated with Prop1:

Gene SymbolEntrez IDGene Name
Prop1 ENSMUSG00000044542.3 Prop1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Prop1mm10_v2_chr11_-_50953745_50953768-0.095.9e-01Click!


Activity profile for motif Prop1.

activity profile for motif Prop1


Sorted Z-values histogram for motif Prop1

Sorted Z-values for motif Prop1



Network of associatons between targets according to the STRING database.



First level regulatory network of Prop1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_+_39287074 15.946 ENSMUST00000003137.8
Cyp2c29
cytochrome P450, family 2, subfamily c, polypeptide 29
chr10_+_128971191 10.417 ENSMUST00000181142.1
9030616G12Rik
RIKEN cDNA 9030616G12 gene
chr7_-_14446570 9.295 ENSMUST00000063509.4
2810007J24Rik
RIKEN cDNA 2810007J24 gene
chr1_+_130826762 9.255 ENSMUST00000133792.1
Pigr
polymeric immunoglobulin receptor
chr7_-_14446651 9.021 ENSMUST00000125941.1
2810007J24Rik
RIKEN cDNA 2810007J24 gene
chr5_-_87091150 8.620 ENSMUST00000154455.1
Ugt2b36
UDP glucuronosyltransferase 2 family, polypeptide B36
chr3_+_138415484 6.385 ENSMUST00000161312.1
ENSMUST00000013458.8
Adh4

alcohol dehydrogenase 4 (class II), pi polypeptide

chr17_+_79626669 6.374 ENSMUST00000086570.1
4921513D11Rik
RIKEN cDNA 4921513D11 gene
chr4_-_96664112 6.259 ENSMUST00000030299.7
Cyp2j5
cytochrome P450, family 2, subfamily j, polypeptide 5
chr9_+_78230644 6.081 ENSMUST00000098537.3
Gsta1
glutathione S-transferase, alpha 1 (Ya)
chr1_+_167598450 6.029 ENSMUST00000111386.1
ENSMUST00000111384.1
Rxrg

retinoid X receptor gamma

chr1_+_167598384 5.557 ENSMUST00000015987.3
Rxrg
retinoid X receptor gamma
chr8_-_5105232 5.160 ENSMUST00000023835.1
Slc10a2
solute carrier family 10, member 2
chr2_-_67194695 4.707 ENSMUST00000147939.1
Gm13598
predicted gene 13598
chr10_-_115362191 4.683 ENSMUST00000092170.5
Tmem19
transmembrane protein 19
chr19_-_40187277 4.661 ENSMUST00000051846.6
Cyp2c70
cytochrome P450, family 2, subfamily c, polypeptide 70
chr10_-_41587753 4.561 ENSMUST00000160751.1
Ccdc162
coiled-coil domain containing 162
chr5_-_87482258 4.507 ENSMUST00000079811.6
ENSMUST00000144144.1
Ugt2a1

UDP glucuronosyltransferase 2 family, polypeptide A1

chr1_-_130661613 4.475 ENSMUST00000027657.7
C4bp
complement component 4 binding protein
chr5_+_130369420 4.423 ENSMUST00000086029.3
Caln1
calneuron 1
chr1_-_130661584 4.418 ENSMUST00000137276.2
C4bp
complement component 4 binding protein
chr11_-_46707059 4.346 ENSMUST00000055102.6
ENSMUST00000125008.1
Timd2

T cell immunoglobulin and mucin domain containing 2

chr18_-_38866702 4.248 ENSMUST00000115582.1
Fgf1
fibroblast growth factor 1
chr16_+_56204313 4.210 ENSMUST00000160116.1
ENSMUST00000069936.7
Impg2

interphotoreceptor matrix proteoglycan 2

chr19_-_39649046 4.093 ENSMUST00000067328.6
Cyp2c67
cytochrome P450, family 2, subfamily c, polypeptide 67
chr3_+_94377505 4.056 ENSMUST00000098877.2
Rorc
RAR-related orphan receptor gamma
chr3_+_94377432 3.980 ENSMUST00000107292.1
Rorc
RAR-related orphan receptor gamma
chr5_-_87535113 3.762 ENSMUST00000120150.1
Sult1b1
sulfotransferase family 1B, member 1
chr4_+_115600975 3.744 ENSMUST00000084342.5
Cyp4a32
cytochrome P450, family 4, subfamily a, polypeptide 32
chr3_-_67515487 3.597 ENSMUST00000178314.1
ENSMUST00000054825.4
Rarres1

retinoic acid receptor responder (tazarotene induced) 1

chr2_+_70474923 3.544 ENSMUST00000100043.2
Sp5
trans-acting transcription factor 5
chr19_+_11536769 3.539 ENSMUST00000025581.6
Ms4a4d
membrane-spanning 4-domains, subfamily A, member 4D
chr5_-_89457763 3.518 ENSMUST00000049209.8
Gc
group specific component
chr3_+_138217814 3.427 ENSMUST00000090171.5
Adh7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chrX_+_38772671 3.299 ENSMUST00000050744.5
6030498E09Rik
RIKEN cDNA 6030498E09 gene
chr9_+_53301571 3.269 ENSMUST00000051014.1
Exph5
exophilin 5
chr7_+_132610620 3.228 ENSMUST00000033241.5
Lhpp
phospholysine phosphohistidine inorganic pyrophosphate phosphatase
chr17_+_85028347 3.220 ENSMUST00000024944.7
Slc3a1
solute carrier family 3, member 1
chrX_-_100594860 3.215 ENSMUST00000053373.1
P2ry4
pyrimidinergic receptor P2Y, G-protein coupled, 4
chr11_+_102041509 3.137 ENSMUST00000123895.1
ENSMUST00000017453.5
ENSMUST00000107163.2
ENSMUST00000107164.2
Cd300lg



CD300 antigen like family member G



chr8_+_127447669 3.118 ENSMUST00000159511.1
Pard3
par-3 (partitioning defective 3) homolog (C. elegans)
chr19_+_12674179 3.070 ENSMUST00000057924.2
Olfr1442
olfactory receptor 1442
chr12_-_57546121 3.060 ENSMUST00000044380.6
Foxa1
forkhead box A1
chr10_-_92375367 2.984 ENSMUST00000182870.1
Gm20757
predicted gene, 20757
chr6_+_149141513 2.933 ENSMUST00000047531.9
ENSMUST00000179873.1
ENSMUST00000111548.1
ENSMUST00000111547.1
ENSMUST00000134306.1
Mettl20




methyltransferase like 20




chr10_-_109009055 2.933 ENSMUST00000156979.1
Syt1
synaptotagmin I
chr18_-_3299537 2.850 ENSMUST00000129435.1
ENSMUST00000122958.1
Crem

cAMP responsive element modulator

chr2_-_164638789 2.812 ENSMUST00000109336.1
Wfdc16
WAP four-disulfide core domain 16
chr11_-_43901187 2.781 ENSMUST00000067258.2
ENSMUST00000139906.1
Adra1b

adrenergic receptor, alpha 1b

chr12_+_9029982 2.768 ENSMUST00000085741.1
Ttc32
tetratricopeptide repeat domain 32
chr6_+_149141638 2.731 ENSMUST00000166416.1
ENSMUST00000111551.1
Mettl20

methyltransferase like 20

chr9_+_7347374 2.687 ENSMUST00000065079.5
ENSMUST00000005950.5
Mmp12

matrix metallopeptidase 12

chr3_+_122419772 2.685 ENSMUST00000029766.4
Bcar3
breast cancer anti-estrogen resistance 3
chr6_+_3993776 2.657 ENSMUST00000031673.5
Gngt1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr11_-_12412136 2.588 ENSMUST00000174874.1
Cobl
cordon-bleu WH2 repeat
chr7_-_34655500 2.567 ENSMUST00000032709.1
Kctd15
potassium channel tetramerisation domain containing 15
chr3_-_146495115 2.504 ENSMUST00000093951.2
Spata1
spermatogenesis associated 1
chrX_-_147429189 2.397 ENSMUST00000033646.2
Il13ra2
interleukin 13 receptor, alpha 2
chr13_+_67833235 2.344 ENSMUST00000060609.7
Gm10037
predicted gene 10037
chr12_-_79190955 2.330 ENSMUST00000085254.6
Rdh11
retinol dehydrogenase 11
chr18_-_3299452 2.324 ENSMUST00000126578.1
Crem
cAMP responsive element modulator
chr4_+_102430047 2.318 ENSMUST00000172616.1
Pde4b
phosphodiesterase 4B, cAMP specific
chr2_-_86347764 2.292 ENSMUST00000099894.2
Olfr1055
olfactory receptor 1055
chr2_-_110305730 2.228 ENSMUST00000046233.2
Bbox1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase 1 (gamma-butyrobetaine hydroxylase)
chr19_-_7966000 2.122 ENSMUST00000182102.1
ENSMUST00000075619.4
Slc22a27

solute carrier family 22, member 27

chr17_-_83846769 2.099 ENSMUST00000000687.7
Haao
3-hydroxyanthranilate 3,4-dioxygenase
chr6_-_115592571 2.089 ENSMUST00000112957.1
2510049J12Rik
RIKEN cDNA 2510049J12 gene
chr5_+_42067960 2.084 ENSMUST00000087332.4
Gm16223
predicted gene 16223
chr4_-_82505707 2.079 ENSMUST00000107248.1
ENSMUST00000107247.1
Nfib

nuclear factor I/B

chr19_+_26749726 2.069 ENSMUST00000175842.1
Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr4_-_108217897 2.065 ENSMUST00000106690.1
ENSMUST00000043793.6
Zyg11a

zyg-11 family member A, cell cycle regulator

chr14_-_45477856 2.060 ENSMUST00000141424.1
Fermt2
fermitin family homolog 2 (Drosophila)
chr3_+_122895072 2.049 ENSMUST00000023820.5
Fabp2
fatty acid binding protein 2, intestinal
chr16_+_20097554 2.018 ENSMUST00000023509.3
Klhl24
kelch-like 24
chr3_-_10331358 1.960 ENSMUST00000065938.8
ENSMUST00000118410.1
Impa1

inositol (myo)-1(or 4)-monophosphatase 1

chr7_+_101321079 1.919 ENSMUST00000032927.7
Stard10
START domain containing 10
chr9_-_71163224 1.894 ENSMUST00000074465.2
Aqp9
aquaporin 9
chr4_+_99030946 1.794 ENSMUST00000030280.6
Angptl3
angiopoietin-like 3
chr13_-_56548534 1.756 ENSMUST00000062806.4
Lect2
leukocyte cell-derived chemotaxin 2
chr11_-_49113757 1.747 ENSMUST00000060398.1
Olfr1396
olfactory receptor 1396
chr17_-_45599603 1.675 ENSMUST00000171847.1
ENSMUST00000166633.1
ENSMUST00000169729.1
Slc29a1


solute carrier family 29 (nucleoside transporters), member 1


chr18_+_32067729 1.656 ENSMUST00000025243.3
Iws1
IWS1 homolog (S. cerevisiae)
chrX_-_165004829 1.621 ENSMUST00000114890.2
Gm17604
predicted gene, 17604
chr2_-_134554348 1.610 ENSMUST00000028704.2
Hao1
hydroxyacid oxidase 1, liver
chr19_-_4698668 1.584 ENSMUST00000177696.1
Gm960
predicted gene 960
chr9_+_66946057 1.571 ENSMUST00000040917.7
ENSMUST00000127896.1
Rps27l

ribosomal protein S27-like

chr1_-_24005608 1.524 ENSMUST00000027338.3
1110058L19Rik
RIKEN cDNA 1110058L19 gene
chr9_+_80165079 1.480 ENSMUST00000184480.1
Myo6
myosin VI
chr5_+_92137896 1.464 ENSMUST00000031355.6
Uso1
USO1 vesicle docking factor
chr1_+_187997835 1.457 ENSMUST00000110938.1
Esrrg
estrogen-related receptor gamma
chr6_-_83121385 1.438 ENSMUST00000146328.1
ENSMUST00000113936.3
ENSMUST00000032111.4
Wbp1


WW domain binding protein 1


chr5_-_62766153 1.437 ENSMUST00000076623.4
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr14_+_73173825 1.423 ENSMUST00000166875.1
Rcbtb2
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr12_+_59129757 1.395 ENSMUST00000069430.8
ENSMUST00000177370.1
Ctage5

CTAGE family, member 5

chr5_+_7960445 1.378 ENSMUST00000115421.1
Steap4
STEAP family member 4
chr6_+_115422040 1.369 ENSMUST00000000450.3
Pparg
peroxisome proliferator activated receptor gamma
chr17_+_64600702 1.367 ENSMUST00000086723.3
Man2a1
mannosidase 2, alpha 1
chr11_-_54249640 1.352 ENSMUST00000019060.5
Csf2
colony stimulating factor 2 (granulocyte-macrophage)
chr16_-_22811399 1.338 ENSMUST00000040592.4
Crygs
crystallin, gamma S
chr10_+_80141457 1.321 ENSMUST00000105367.1
Atp5d
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
chr5_-_90223923 1.316 ENSMUST00000118816.1
ENSMUST00000048363.7
Cox18

cytochrome c oxidase assembly protein 18

chr1_-_163725123 1.305 ENSMUST00000159679.1
Mettl11b
methyltransferase like 11B
chr9_-_121857952 1.302 ENSMUST00000060251.6
Higd1a
HIG1 domain family, member 1A
chr7_+_105375053 1.289 ENSMUST00000106805.2
Gm5901
predicted gene 5901
chr7_+_62476306 1.284 ENSMUST00000097132.3
Atp5l-ps1
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit g, pseudogene 1
chr4_-_14826582 1.279 ENSMUST00000117268.1
Otud6b
OTU domain containing 6B
chr12_+_59129720 1.262 ENSMUST00000175912.1
ENSMUST00000176892.1
Ctage5

CTAGE family, member 5

chr12_-_104473236 1.258 ENSMUST00000021513.4
Gsc
goosecoid homeobox
chr4_+_95557494 1.254 ENSMUST00000079223.4
ENSMUST00000177394.1
Fggy

FGGY carbohydrate kinase domain containing

chr3_-_92123943 1.237 ENSMUST00000070284.3
Prr9
proline rich 9
chr15_+_76343504 1.231 ENSMUST00000023210.6
Cyc1
cytochrome c-1
chr4_-_12087912 1.212 ENSMUST00000050686.3
Tmem67
transmembrane protein 67
chr8_+_13060908 1.210 ENSMUST00000033822.2
Proz
protein Z, vitamin K-dependent plasma glycoprotein
chr1_+_58711488 1.196 ENSMUST00000097722.2
ENSMUST00000114313.1
Cflar

CASP8 and FADD-like apoptosis regulator

chr2_+_82053222 1.188 ENSMUST00000047527.7
Zfp804a
zinc finger protein 804A
chr13_-_4609122 1.168 ENSMUST00000110691.3
ENSMUST00000091848.5
Akr1e1

aldo-keto reductase family 1, member E1

chr18_+_3382979 1.151 ENSMUST00000025073.5
Cul2
cullin 2
chr9_+_118478182 1.136 ENSMUST00000111763.1
Eomes
eomesodermin homolog (Xenopus laevis)
chr1_+_187997821 1.134 ENSMUST00000027906.6
Esrrg
estrogen-related receptor gamma
chr19_-_39812744 1.106 ENSMUST00000162507.1
ENSMUST00000160476.1
Cyp2c40

cytochrome P450, family 2, subfamily c, polypeptide 40

chr3_-_116712644 1.085 ENSMUST00000029569.2
Slc35a3
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3
chr4_-_82505749 1.073 ENSMUST00000107245.2
ENSMUST00000107246.1
Nfib

nuclear factor I/B

chr1_-_186117251 1.069 ENSMUST00000045388.7
Lyplal1
lysophospholipase-like 1
chrX_+_38600626 1.066 ENSMUST00000000365.2
Mcts1
malignant T cell amplified sequence 1
chr4_-_41517326 1.053 ENSMUST00000030152.6
ENSMUST00000095126.4
1110017D15Rik

RIKEN cDNA 1110017D15 gene

chr18_+_38296805 1.047 ENSMUST00000171461.1
Rnf14
ring finger protein 14
chr11_+_109543694 1.040 ENSMUST00000106696.1
Arsg
arylsulfatase G
chrX_+_56963325 1.032 ENSMUST00000096431.3
Gpr112
G protein-coupled receptor 112
chr2_-_33942111 1.025 ENSMUST00000130988.1
ENSMUST00000127936.1
ENSMUST00000134271.1
Gm13403


predicted gene 13403


chr8_+_47822143 1.022 ENSMUST00000079639.2
Cldn24
claudin 24
chrX_-_134276888 1.002 ENSMUST00000113252.1
Trmt2b
TRM2 tRNA methyltransferase 2B
chr13_+_40704005 0.990 ENSMUST00000069457.1
Gm9979
predicted gene 9979
chr16_-_64771146 0.987 ENSMUST00000076991.6
4930453N24Rik
RIKEN cDNA 4930453N24 gene
chrM_+_10167 0.978 ENSMUST00000082414.1
mt-Nd4
mitochondrially encoded NADH dehydrogenase 4
chr12_+_85110833 0.972 ENSMUST00000053811.8
Dlst
dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
chr14_+_73237891 0.961 ENSMUST00000044405.6
Lpar6
lysophosphatidic acid receptor 6
chr14_+_74735641 0.945 ENSMUST00000177283.1
Esd
esterase D/formylglutathione hydrolase
chr5_+_104170676 0.942 ENSMUST00000112771.1
Dspp
dentin sialophosphoprotein
chrM_+_2743 0.940 ENSMUST00000082392.1
mt-Nd1
mitochondrially encoded NADH dehydrogenase 1
chr3_-_116712696 0.933 ENSMUST00000169530.1
Slc35a3
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3
chr4_+_116507549 0.933 ENSMUST00000106479.1
ENSMUST00000030461.4
Ipp

IAP promoted placental gene

chr2_+_85975213 0.920 ENSMUST00000082191.2
Olfr1029
olfactory receptor 1029
chr10_+_69925954 0.910 ENSMUST00000181974.1
ENSMUST00000182795.1
ENSMUST00000182437.1
Ank3


ankyrin 3, epithelial


chrM_+_9870 0.904 ENSMUST00000084013.1
mt-Nd4l
mitochondrially encoded NADH dehydrogenase 4L
chr1_-_171240055 0.893 ENSMUST00000131286.1
Ndufs2
NADH dehydrogenase (ubiquinone) Fe-S protein 2
chr10_+_69925766 0.892 ENSMUST00000182269.1
ENSMUST00000183261.1
ENSMUST00000183074.1
Ank3


ankyrin 3, epithelial


chr9_+_119341487 0.886 ENSMUST00000175743.1
ENSMUST00000176397.1
Acaa1a

acetyl-Coenzyme A acyltransferase 1A

chr1_+_37872333 0.885 ENSMUST00000142670.1
Lipt1
lipoyltransferase 1
chr9_+_105642957 0.874 ENSMUST00000065778.6
Pik3r4
phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 4, p150
chr9_+_119341294 0.852 ENSMUST00000039784.5
Acaa1a
acetyl-Coenzyme A acyltransferase 1A
chr17_+_94873986 0.844 ENSMUST00000108007.4
Gm20939
predicted gene, 20939
chr2_+_20737306 0.841 ENSMUST00000114606.1
ENSMUST00000114608.1
Etl4

enhancer trap locus 4

chrX_-_134276969 0.837 ENSMUST00000087541.5
ENSMUST00000087540.3
Trmt2b

TRM2 tRNA methyltransferase 2B

chr18_-_9282754 0.836 ENSMUST00000041007.3
Gjd4
gap junction protein, delta 4
chr10_+_69925800 0.831 ENSMUST00000182029.1
Ank3
ankyrin 3, epithelial
chrX_+_103630575 0.828 ENSMUST00000033692.7
Zcchc13
zinc finger, CCHC domain containing 13
chr12_+_31390843 0.825 ENSMUST00000167432.1
Slc26a3
solute carrier family 26, member 3
chr1_-_56969864 0.801 ENSMUST00000177424.1
Satb2
special AT-rich sequence binding protein 2
chr18_+_74442551 0.774 ENSMUST00000121875.1
Myo5b
myosin VB
chr5_-_129708511 0.763 ENSMUST00000182386.1
Sept14
septin 14
chr14_-_48667508 0.761 ENSMUST00000144465.1
ENSMUST00000133479.1
ENSMUST00000119070.1
ENSMUST00000152018.1
Otx2



orthodenticle homolog 2 (Drosophila)



chr9_-_59353430 0.761 ENSMUST00000026265.6
Bbs4
Bardet-Biedl syndrome 4 (human)
chr8_-_85432841 0.759 ENSMUST00000047749.5
4921524J17Rik
RIKEN cDNA 4921524J17 gene
chr4_-_110292719 0.758 ENSMUST00000106601.1
Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr7_-_30856178 0.757 ENSMUST00000094583.1
Ffar3
free fatty acid receptor 3
chr9_+_118478344 0.757 ENSMUST00000035020.8
Eomes
eomesodermin homolog (Xenopus laevis)
chr12_-_87919857 0.756 ENSMUST00000180053.1
Gm2035
predicted pseudogene 2035
chr6_-_136173492 0.755 ENSMUST00000111905.1
Grin2b
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chr7_+_66365905 0.743 ENSMUST00000107486.1
Gm10974
predicted gene 10974
chr6_-_117214048 0.741 ENSMUST00000170447.1
Rpl28-ps4
ribosomal protein L28, pseudogene 4
chr6_+_63255971 0.736 ENSMUST00000159561.1
ENSMUST00000095852.3
Grid2

glutamate receptor, ionotropic, delta 2

chr5_-_86745787 0.733 ENSMUST00000161306.1
Tmprss11e
transmembrane protease, serine 11e
chr11_-_117873433 0.725 ENSMUST00000033230.7
Tha1
threonine aldolase 1
chrM_+_7759 0.689 ENSMUST00000082407.1
ENSMUST00000082408.1
mt-Atp8
mt-Atp6
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chr8_-_21327015 0.686 ENSMUST00000098890.3
Defa-rs1
defensin, alpha, related sequence 1
chr8_+_21509258 0.680 ENSMUST00000084042.3
Defa20
defensin, alpha, 20
chr16_+_4741543 0.680 ENSMUST00000120232.1
Hmox2
heme oxygenase (decycling) 2
chr1_-_24612700 0.674 ENSMUST00000088336.1
Gm10222
predicted gene 10222
chr16_-_55283237 0.667 ENSMUST00000036412.3
Zpld1
zona pellucida like domain containing 1
chr2_-_112480817 0.662 ENSMUST00000099589.2
Chrm5
cholinergic receptor, muscarinic 5
chr12_-_84617326 0.661 ENSMUST00000021666.4
Abcd4
ATP-binding cassette, sub-family D (ALD), member 4
chr4_+_35152056 0.655 ENSMUST00000058595.6
Ifnk
interferon kappa
chr2_-_176149825 0.653 ENSMUST00000109049.3
ENSMUST00000179349.1
Gm2004

predicted gene 2004

chr11_+_101087277 0.650 ENSMUST00000107302.1
ENSMUST00000107303.3
ENSMUST00000017945.8
ENSMUST00000149597.1
Mlx



MAX-like protein X



chr14_+_52726612 0.649 ENSMUST00000184883.1
Trav6d-3
T cell receptor alpha variable 6D-3
chr1_+_37872206 0.647 ENSMUST00000041621.3
Lipt1
lipoyltransferase 1
chr7_-_24724237 0.638 ENSMUST00000081657.4
Gm4763
predicted gene 4763
chr3_+_32436376 0.624 ENSMUST00000108242.1
Pik3ca
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr5_-_123666682 0.604 ENSMUST00000149410.1
Clip1
CAP-GLY domain containing linker protein 1
chr14_+_4709238 0.601 ENSMUST00000169465.1
ENSMUST00000171305.1
Gm7876

predicted gene 7876

chr3_-_96905294 0.595 ENSMUST00000029738.7
Gpr89
G protein-coupled receptor 89
chr11_-_99337930 0.594 ENSMUST00000100482.2
Krt26
keratin 26
chr3_+_83026147 0.588 ENSMUST00000166581.1
ENSMUST00000029630.9
Fga

fibrinogen alpha chain

chr10_+_69925484 0.584 ENSMUST00000182692.1
ENSMUST00000092433.5
Ank3

ankyrin 3, epithelial

chr19_-_45235811 0.584 ENSMUST00000099401.4
Lbx1
ladybird homeobox homolog 1 (Drosophila)
chr19_-_19001099 0.581 ENSMUST00000040153.8
ENSMUST00000112828.1
Rorb

RAR-related orphan receptor beta

chr2_+_125136692 0.581 ENSMUST00000099452.2
Ctxn2
cortexin 2
chr8_+_21665797 0.579 ENSMUST00000075268.4
Gm15315
predicted gene 15315
chr7_+_126976338 0.575 ENSMUST00000032920.3
Cdipt
CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)
chr18_+_52615908 0.573 ENSMUST00000072666.3
Zfp474
zinc finger protein 474

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 12.4 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
2.5 9.8 GO:0006069 ethanol oxidation(GO:0006069)
1.6 6.3 GO:0001998 angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001998)
1.3 3.8 GO:0006067 ethanol metabolic process(GO:0006067)
1.0 3.1 GO:0061144 alveolar secondary septum development(GO:0061144)
0.9 2.8 GO:0001982 baroreceptor response to decreased systemic arterial blood pressure(GO:0001982)
0.8 4.2 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.8 26.3 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.8 3.2 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.7 3.7 GO:0036102 leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102)
0.7 8.0 GO:0072615 interleukin-17 secretion(GO:0072615)
0.6 2.3 GO:0016062 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.6 2.2 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.6 1.7 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.5 1.6 GO:0034310 primary alcohol catabolic process(GO:0034310)
0.5 0.5 GO:1904444 regulation of establishment of Sertoli cell barrier(GO:1904444)
0.5 3.1 GO:0003383 apical constriction(GO:0003383)
0.5 1.5 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.5 1.9 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.5 1.4 GO:2000229 pancreatic stellate cell proliferation(GO:0072343) regulation of pancreatic stellate cell proliferation(GO:2000229)
0.4 2.7 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.4 2.0 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788)
0.4 3.2 GO:0030321 transepithelial chloride transport(GO:0030321)
0.4 1.2 GO:1901740 negative regulation of myoblast fusion(GO:1901740)
0.4 1.9 GO:0015855 purine nucleobase transport(GO:0006863) nucleobase transport(GO:0015851) pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
0.4 2.6 GO:0001757 somite specification(GO:0001757)
0.4 1.8 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.3 1.6 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.3 0.9 GO:0046294 formaldehyde catabolic process(GO:0046294)
0.3 1.3 GO:0014036 neural crest cell fate specification(GO:0014036)
0.3 0.9 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.3 3.2 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.3 11.6 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.3 2.9 GO:0005513 detection of calcium ion(GO:0005513)
0.3 1.1 GO:0002188 translation reinitiation(GO:0002188)
0.3 2.4 GO:0043305 negative regulation of mast cell degranulation(GO:0043305)
0.3 4.5 GO:0052695 cellular glucuronidation(GO:0052695)
0.3 2.1 GO:0046874 quinolinate metabolic process(GO:0046874)
0.3 0.8 GO:0002877 regulation of acute inflammatory response to non-antigenic stimulus(GO:0002877) positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.2 1.9 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.2 1.7 GO:0015862 uridine transport(GO:0015862) pyrimidine nucleoside transport(GO:0015864)
0.2 1.7 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.2 6.1 GO:0035634 response to stilbenoid(GO:0035634)
0.2 2.1 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.2 0.7 GO:0006788 heme oxidation(GO:0006788)
0.2 0.8 GO:0014717 regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014717) satellite cell activation involved in skeletal muscle regeneration(GO:0014901)
0.2 1.2 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.2 0.8 GO:0032439 endosome localization(GO:0032439)
0.2 1.4 GO:0042045 epithelial fluid transport(GO:0042045)
0.2 0.6 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.2 5.7 GO:0097286 iron ion import(GO:0097286)
0.2 0.8 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.2 5.5 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.2 1.3 GO:0051204 protein insertion into mitochondrial membrane(GO:0051204)
0.2 3.5 GO:0042359 vitamin D metabolic process(GO:0042359)
0.2 0.7 GO:0006566 threonine metabolic process(GO:0006566)
0.2 1.1 GO:0002084 protein depalmitoylation(GO:0002084) negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.2 8.9 GO:0006958 complement activation, classical pathway(GO:0006958)
0.2 0.5 GO:1905223 epicardium morphogenesis(GO:1905223)
0.2 0.8 GO:0045852 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.2 2.0 GO:0006020 inositol metabolic process(GO:0006020)
0.2 3.3 GO:0003334 keratinocyte development(GO:0003334)
0.2 1.4 GO:0006013 mannose metabolic process(GO:0006013)
0.2 2.1 GO:0015747 urate transport(GO:0015747)
0.2 0.6 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.1 0.4 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.1 0.6 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.7 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.1 3.5 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.1 0.5 GO:0015817 histidine transport(GO:0015817)
0.1 0.8 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.1 0.8 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.1 0.9 GO:0030242 autophagy of peroxisome(GO:0030242) peroxisome disassembly(GO:1905683)
0.1 1.0 GO:0009249 protein lipoylation(GO:0009249)
0.1 1.5 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 0.6 GO:1903587 negative regulation of peptidyl-serine dephosphorylation(GO:1902309) regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
0.1 0.5 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.1 0.9 GO:0033227 dsRNA transport(GO:0033227)
0.1 1.2 GO:0010826 negative regulation of centrosome duplication(GO:0010826)
0.1 1.5 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.1 0.5 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.1 0.2 GO:0014873 response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.1 0.7 GO:0009235 cobalamin metabolic process(GO:0009235)
0.1 1.3 GO:0019321 pentose metabolic process(GO:0019321)
0.1 0.4 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.1 0.3 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.1 5.5 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.1 0.3 GO:0046381 CMP-N-acetylneuraminate metabolic process(GO:0046381)
0.1 1.0 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1 1.1 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.3 GO:2000293 negative regulation of eating behavior(GO:1903999) regulation of defecation(GO:2000292) negative regulation of defecation(GO:2000293)
0.1 2.6 GO:0007602 phototransduction(GO:0007602)
0.1 2.7 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.1 0.3 GO:0060126 somatotropin secreting cell differentiation(GO:0060126)
0.1 1.0 GO:1902004 positive regulation of amyloid-beta formation(GO:1902004)
0.1 1.6 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.1 0.6 GO:0046549 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.1 1.1 GO:0042407 cristae formation(GO:0042407)
0.1 2.0 GO:0050892 intestinal absorption(GO:0050892)
0.1 1.7 GO:0008206 bile acid metabolic process(GO:0008206)
0.1 0.2 GO:0061075 cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.1 0.6 GO:0048664 neuron fate determination(GO:0048664)
0.1 0.7 GO:1904861 excitatory synapse assembly(GO:1904861)
0.1 0.2 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 1.0 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 2.6 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.1 0.5 GO:0007182 common-partner SMAD protein phosphorylation(GO:0007182) positive regulation of interleukin-2 secretion(GO:1900042)
0.0 0.4 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.0 1.3 GO:0090201 negative regulation of release of cytochrome c from mitochondria(GO:0090201)
0.0 0.8 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.9 GO:0033194 response to hydroperoxide(GO:0033194)
0.0 0.4 GO:2000252 negative regulation of feeding behavior(GO:2000252)
0.0 1.8 GO:0030488 tRNA methylation(GO:0030488)
0.0 3.6 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.2 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 1.0 GO:0006103 2-oxoglutarate metabolic process(GO:0006103)
0.0 1.3 GO:0031365 N-terminal protein amino acid modification(GO:0031365)
0.0 0.4 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.0 0.1 GO:2000791 regulation of mesenchymal cell proliferation involved in lung development(GO:2000790) negative regulation of mesenchymal cell proliferation involved in lung development(GO:2000791)
0.0 2.1 GO:0051438 regulation of ubiquitin-protein transferase activity(GO:0051438)
0.0 0.3 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.1 GO:0060591 chondroblast differentiation(GO:0060591)
0.0 1.0 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 2.1 GO:0007601 visual perception(GO:0007601)
0.0 0.2 GO:0090315 negative regulation of protein targeting to membrane(GO:0090315)
0.0 0.7 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.1 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.0 0.3 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 2.1 GO:0048041 cell-substrate adherens junction assembly(GO:0007045) focal adhesion assembly(GO:0048041)
0.0 1.2 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0 0.3 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.7 GO:0019731 antibacterial humoral response(GO:0019731)
0.0 0.6 GO:0051452 intracellular pH reduction(GO:0051452)
0.0 0.0 GO:0034184 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.0 0.5 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.4 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.2 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.0 0.2 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.2 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 0.2 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.0 0.4 GO:0034389 lipid particle organization(GO:0034389)
0.0 2.2 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.0 0.1 GO:1900003 negative regulation of fertilization(GO:0060467) regulation of serine-type endopeptidase activity(GO:1900003) negative regulation of serine-type endopeptidase activity(GO:1900004) regulation of serine-type peptidase activity(GO:1902571) negative regulation of serine-type peptidase activity(GO:1902572)
0.0 1.2 GO:0030216 keratinocyte differentiation(GO:0030216)
0.0 2.0 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.0 GO:1904430 negative regulation of t-circle formation(GO:1904430)
0.0 0.2 GO:0008053 mitochondrial fusion(GO:0008053)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.2 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.6 1.7 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.4 3.1 GO:0033269 internode region of axon(GO:0033269)
0.3 2.6 GO:1990357 terminal web(GO:1990357)
0.3 0.9 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.2 1.2 GO:0030891 VCB complex(GO:0030891)
0.2 9.3 GO:0055038 recycling endosome membrane(GO:0055038)
0.2 2.1 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.2 1.2 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.2 2.8 GO:0045179 apical cortex(GO:0045179)
0.2 2.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.2 1.3 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.2 2.9 GO:0031045 dense core granule(GO:0031045)
0.2 3.2 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 1.9 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 4.4 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 0.6 GO:0005745 m-AAA complex(GO:0005745)
0.1 3.2 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 1.9 GO:0022627 small ribosomal subunit(GO:0015935) cytosolic small ribosomal subunit(GO:0022627)
0.1 1.2 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.1 1.1 GO:0002177 manchette(GO:0002177)
0.1 2.0 GO:0071564 npBAF complex(GO:0071564)
0.1 1.0 GO:0016324 apical plasma membrane(GO:0016324)
0.1 1.0 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 0.5 GO:0008091 spectrin(GO:0008091) cuticular plate(GO:0032437)
0.1 2.3 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 0.4 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 0.6 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 1.2 GO:0036038 MKS complex(GO:0036038)
0.1 2.3 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.1 1.5 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.1 0.8 GO:0034464 BBSome(GO:0034464)
0.1 2.0 GO:0030057 desmosome(GO:0030057)
0.1 0.6 GO:0005577 fibrinogen complex(GO:0005577)
0.1 5.2 GO:0000502 proteasome complex(GO:0000502)
0.1 0.2 GO:0031021 interphase microtubule organizing center(GO:0031021)
0.1 4.9 GO:0070469 respiratory chain(GO:0070469)
0.1 1.4 GO:0005797 Golgi medial cisterna(GO:0005797)
0.1 0.8 GO:0042788 polysomal ribosome(GO:0042788)
0.1 3.5 GO:0031941 filamentous actin(GO:0031941)
0.1 0.8 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.7 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.6 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 1.8 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.3 GO:0000813 ESCRT I complex(GO:0000813)
0.0 1.2 GO:0001533 cornified envelope(GO:0001533)
0.0 4.0 GO:0031526 brush border membrane(GO:0031526)
0.0 0.8 GO:0005922 connexin complex(GO:0005922)
0.0 8.4 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 3.5 GO:0072562 blood microparticle(GO:0072562)
0.0 0.3 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.1 GO:0044305 calyx of Held(GO:0044305)
0.0 8.0 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 1.1 GO:0098878 neurotransmitter receptor complex(GO:0098878)
0.0 2.0 GO:0005882 intermediate filament(GO:0005882)
0.0 2.3 GO:0005902 microvillus(GO:0005902)
0.0 0.0 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.0 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 0.5 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.1 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0 1.5 GO:0000139 Golgi membrane(GO:0000139)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 9.8 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
2.7 15.9 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
1.6 8.0 GO:0008142 oxysterol binding(GO:0008142)
1.2 11.6 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
1.1 3.2 GO:0071553 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.9 9.3 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.9 3.5 GO:1902271 D3 vitamins binding(GO:1902271)
0.9 4.3 GO:0070287 ferritin receptor activity(GO:0070287)
0.8 3.2 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.8 3.8 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.7 5.2 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.7 2.9 GO:0030348 syntaxin-3 binding(GO:0030348)
0.7 2.8 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.7 2.0 GO:0031403 lithium ion binding(GO:0031403)
0.6 3.7 GO:0050051 alkane 1-monooxygenase activity(GO:0018685) leukotriene-B4 20-monooxygenase activity(GO:0050051)
0.5 1.5 GO:0016979 lipoate-protein ligase activity(GO:0016979)
0.5 12.5 GO:0070330 aromatase activity(GO:0070330)
0.4 1.3 GO:0019150 D-ribulokinase activity(GO:0019150)
0.4 1.6 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.4 3.1 GO:0019865 immunoglobulin binding(GO:0019865)
0.4 1.9 GO:0005345 purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205) glycerol channel activity(GO:0015254)
0.4 1.8 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.3 13.1 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.3 2.3 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.3 1.0 GO:0016748 succinyltransferase activity(GO:0016748)
0.3 0.9 GO:0018738 S-formylglutathione hydrolase activity(GO:0018738)
0.3 1.8 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.3 2.0 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.3 1.7 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.3 4.0 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.3 4.2 GO:0044548 S100 protein binding(GO:0044548)
0.2 0.7 GO:0008732 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.2 2.6 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.2 6.1 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.2 1.6 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.2 4.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 1.4 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.2 0.7 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.2 1.5 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.2 1.6 GO:0008494 translation activator activity(GO:0008494)
0.2 0.9 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.2 1.7 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1 0.4 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.1 2.1 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 1.0 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 1.4 GO:0050543 icosatetraenoic acid binding(GO:0050543) arachidonic acid binding(GO:0050544)
0.1 0.4 GO:0022850 serotonin-gated cation-selective channel activity(GO:0022850)
0.1 1.4 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.1 3.6 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.6 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 7.1 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 0.3 GO:0030338 CMP-N-acetylneuraminate monooxygenase activity(GO:0030338)
0.1 1.7 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.1 1.1 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.5 GO:0005290 L-histidine transmembrane transporter activity(GO:0005290)
0.1 2.1 GO:0019825 oxygen binding(GO:0019825)
0.1 0.7 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 0.8 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.1 2.0 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.1 1.0 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 0.3 GO:0102007 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.1 1.2 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 1.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 3.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 1.0 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.1 0.8 GO:0034452 dynactin binding(GO:0034452)
0.1 0.7 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 0.4 GO:0034056 estrogen response element binding(GO:0034056)
0.1 1.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 2.6 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.5 GO:0004659 prenyltransferase activity(GO:0004659)
0.1 2.3 GO:0030552 cAMP binding(GO:0030552)
0.1 2.7 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 0.4 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.2 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211)
0.1 1.2 GO:0051787 misfolded protein binding(GO:0051787)
0.1 3.8 GO:0005549 odorant binding(GO:0005549)
0.0 0.8 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 1.9 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.7 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
0.0 0.4 GO:0002134 UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.0 2.4 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 2.5 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.0 0.3 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 1.3 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 1.9 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.0 1.1 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.7 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 1.4 GO:0050699 WW domain binding(GO:0050699)
0.0 2.7 GO:0005518 collagen binding(GO:0005518)
0.0 0.5 GO:0004549 tRNA-specific ribonuclease activity(GO:0004549)
0.0 0.6 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.4 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.6 GO:0008308 voltage-gated anion channel activity(GO:0008308)
0.0 4.1 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 2.4 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 3.8 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.0 0.8 GO:0017091 AU-rich element binding(GO:0017091)
0.0 1.3 GO:0020037 heme binding(GO:0020037)
0.0 0.7 GO:0015399 primary active transmembrane transporter activity(GO:0015399) P-P-bond-hydrolysis-driven transmembrane transporter activity(GO:0015405) ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 0.9 GO:0035004 phosphatidylinositol 3-kinase activity(GO:0035004)
0.0 0.9 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.5 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.4 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.1 GO:0036122 BMP binding(GO:0036122)
0.0 1.9 GO:0003774 motor activity(GO:0003774)
0.0 1.0 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.0 GO:0030060 L-malate dehydrogenase activity(GO:0030060)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.4 ST_IL_13_PATHWAY Interleukin 13 (IL-13) Pathway
0.2 13.0 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 5.9 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 1.2 SA_FAS_SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 6.2 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.1 4.5 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.1 4.6 SIG_CD40PATHWAYMAP Genes related to CD40 signaling
0.1 3.3 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 1.8 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.0 1.5 PID_ARF_3PATHWAY Arf1 pathway
0.0 1.9 PID_ARF6_PATHWAY Arf6 signaling events
0.0 1.2 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 3.1 SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES Genes related to the insulin receptor pathway
0.0 2.4 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.0 1.8 PID_CD8_TCR_DOWNSTREAM_PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.5 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.5 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 3.3 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.6 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 1.2 PID_LYSOPHOSPHOLIPID_PATHWAY LPA receptor mediated events
0.0 1.5 PID_AVB3_INTEGRIN_PATHWAY Integrins in angiogenesis
0.0 0.8 PID_REELIN_PATHWAY Reelin signaling pathway
0.0 0.5 PID_A6B1_A6B4_INTEGRIN_PATHWAY a6b1 and a6b4 Integrin signaling
0.0 1.3 PID_RB_1PATHWAY Regulation of retinoblastoma protein
0.0 0.9 PID_P73PATHWAY p73 transcription factor network
0.0 0.5 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.0 1.6 PID_P53_DOWNSTREAM_PATHWAY Direct p53 effectors

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 9.8 REACTOME_ETHANOL_OXIDATION Genes involved in Ethanol oxidation
0.6 5.2 REACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS Genes involved in Recycling of bile acids and salts
0.5 2.7 REACTOME_OLFACTORY_SIGNALING_PATHWAY Genes involved in Olfactory Signaling Pathway
0.3 4.5 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.3 3.8 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.3 24.2 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.2 4.2 REACTOME_FGFR4_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.2 2.9 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.2 2.5 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.2 1.9 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 3.6 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 6.1 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.1 5.8 REACTOME_METABOLISM_OF_STEROID_HORMONES_AND_VITAMINS_A_AND_D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.1 3.2 REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 2.1 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism
0.1 1.0 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 1.2 REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 1.2 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 3.7 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 3.7 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 2.1 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 1.5 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.1 3.0 REACTOME_IL_RECEPTOR_SHC_SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 1.3 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 3.2 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 1.2 REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 0.6 REACTOME_COMMON_PATHWAY Genes involved in Common Pathway
0.1 0.9 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 1.4 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION_IN_THE_MEDIAL_TRANS_GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 1.0 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.8 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.0 0.8 REACTOME_REGULATION_OF_WATER_BALANCE_BY_RENAL_AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 2.1 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.0 0.8 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.7 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.3 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation
0.0 1.1 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.5 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.0 0.3 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 3.4 REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.4 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.4 REACTOME_LIGAND_GATED_ION_CHANNEL_TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.8 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 1.8 REACTOME_G_ALPHA_S_SIGNALLING_EVENTS Genes involved in G alpha (s) signalling events
0.0 0.3 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.1 REACTOME_DEFENSINS Genes involved in Defensins