Motif ID: Ptf1a

Z-value: 1.452


Transcription factors associated with Ptf1a:

Gene SymbolEntrez IDGene Name
Ptf1a ENSMUSG00000026735.2 Ptf1a

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Ptf1amm10_v2_chr2_+_19445632_194456630.782.7e-08Click!


Activity profile for motif Ptf1a.

activity profile for motif Ptf1a


Sorted Z-values histogram for motif Ptf1a

Sorted Z-values for motif Ptf1a



Network of associatons between targets according to the STRING database.



First level regulatory network of Ptf1a

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_41314700 29.300 ENSMUST00000064324.5
Try5
trypsin 5
chr6_+_41458923 22.613 ENSMUST00000031910.7
Prss1
protease, serine, 1 (trypsin 1)
chr6_+_41392356 22.339 ENSMUST00000049079.7
Gm5771
predicted gene 5771
chr7_+_28540863 18.761 ENSMUST00000119180.2
Sycn
syncollin
chr6_+_41354105 18.509 ENSMUST00000072103.5
Try10
trypsin 10
chr6_+_41302265 16.943 ENSMUST00000031913.4
Try4
trypsin 4
chr7_-_131322292 15.519 ENSMUST00000046611.7
Cuzd1
CUB and zona pellucida-like domains 1
chr2_+_173153048 7.255 ENSMUST00000029017.5
Pck1
phosphoenolpyruvate carboxykinase 1, cytosolic
chr6_-_69243445 6.432 ENSMUST00000101325.3
Igkv4-71
immunoglobulin kappa chain variable 4-71
chr1_-_90153396 3.533 ENSMUST00000113094.2
Iqca
IQ motif containing with AAA domain
chr10_+_95417352 3.532 ENSMUST00000181781.1
5730420D15Rik
RIKEN cDNA 5730420D15 gene
chr14_-_63417125 3.356 ENSMUST00000014597.3
Blk
B lymphoid kinase
chr11_+_101330605 3.031 ENSMUST00000103105.3
Aoc3
amine oxidase, copper containing 3
chr8_+_105048592 2.914 ENSMUST00000093222.5
ENSMUST00000093223.3
Ces3a

carboxylesterase 3A

chrX_+_160390684 2.635 ENSMUST00000112408.2
ENSMUST00000112402.1
ENSMUST00000112401.1
ENSMUST00000112400.1
ENSMUST00000112405.2
ENSMUST00000112404.2
ENSMUST00000146805.1
Gpr64






G protein-coupled receptor 64






chrX_-_162964557 2.074 ENSMUST00000038769.2
S100g
S100 calcium binding protein G
chr7_-_3249711 1.919 ENSMUST00000108653.2
Nlrp12
NLR family, pyrin domain containing 12
chr15_-_77399086 1.742 ENSMUST00000175919.1
ENSMUST00000176074.1
Apol7a

apolipoprotein L 7a

chr14_-_33185489 1.720 ENSMUST00000159606.1
Wdfy4
WD repeat and FYVE domain containing 4
chr11_+_120633719 1.673 ENSMUST00000181502.1
Gm17586
predicted gene, 17586
chr3_+_138277489 1.543 ENSMUST00000004232.9
Adh1
alcohol dehydrogenase 1 (class I)
chr11_+_4031770 1.512 ENSMUST00000019512.7
Sec14l4
SEC14-like 4 (S. cerevisiae)
chr11_-_99155067 1.403 ENSMUST00000103134.3
Ccr7
chemokine (C-C motif) receptor 7
chr10_-_95417099 1.362 ENSMUST00000135822.1
Socs2
suppressor of cytokine signaling 2
chr2_+_164948219 1.351 ENSMUST00000017881.2
Mmp9
matrix metallopeptidase 9
chr16_+_91269759 1.239 ENSMUST00000056882.5
Olig1
oligodendrocyte transcription factor 1
chr7_-_30944017 1.195 ENSMUST00000062620.7
Hamp
hepcidin antimicrobial peptide
chr7_-_140102367 1.142 ENSMUST00000142105.1
Fuom
fucose mutarotase
chr2_+_11705712 1.034 ENSMUST00000138856.1
ENSMUST00000078834.5
ENSMUST00000114834.3
ENSMUST00000114833.3
ENSMUST00000114831.2
ENSMUST00000114832.2
Il15ra





interleukin 15 receptor, alpha chain





chr10_-_77089428 1.005 ENSMUST00000156009.1
Col18a1
collagen, type XVIII, alpha 1
chr2_-_148038270 0.996 ENSMUST00000132070.1
9030622O22Rik
RIKEN cDNA 9030622O22 gene
chr14_-_55944536 0.970 ENSMUST00000022834.6
Cma1
chymase 1, mast cell
chr11_-_90390895 0.921 ENSMUST00000004051.7
Hlf
hepatic leukemia factor
chr11_+_78465697 0.870 ENSMUST00000001126.3
Slc46a1
solute carrier family 46, member 1
chr14_+_52792208 0.850 ENSMUST00000178426.2
Trav9d-1
T cell receptor alpha variable 9D-1
chr17_-_28517509 0.848 ENSMUST00000114792.1
ENSMUST00000177939.1
Fkbp5

FK506 binding protein 5

chr11_-_6444352 0.841 ENSMUST00000093346.5
ENSMUST00000109737.2
H2afv

H2A histone family, member V

chr14_-_70207637 0.836 ENSMUST00000022682.5
Sorbs3
sorbin and SH3 domain containing 3
chr6_-_136781718 0.828 ENSMUST00000078095.6
ENSMUST00000032338.7
Gucy2c

guanylate cyclase 2c

chr10_+_127048235 0.824 ENSMUST00000165764.1
Cyp27b1
cytochrome P450, family 27, subfamily b, polypeptide 1
chr5_-_120887582 0.823 ENSMUST00000086368.5
Oas1g
2'-5' oligoadenylate synthetase 1G
chr5_-_99252839 0.771 ENSMUST00000168092.1
ENSMUST00000031276.8
Rasgef1b

RasGEF domain family, member 1B

chr2_-_30415302 0.767 ENSMUST00000132981.2
ENSMUST00000129494.1
Crat

carnitine acetyltransferase

chr10_-_75932468 0.716 ENSMUST00000120281.1
ENSMUST00000000924.6
Mmp11

matrix metallopeptidase 11

chr9_-_106476590 0.677 ENSMUST00000112479.2
Parp3
poly (ADP-ribose) polymerase family, member 3
chr4_-_155010984 0.661 ENSMUST00000105631.2
ENSMUST00000139976.2
ENSMUST00000145662.2
Plch2


phospholipase C, eta 2


chr7_+_104329471 0.634 ENSMUST00000180136.1
ENSMUST00000178316.1
Trim34b

tripartite motif-containing 34B

chr15_+_31276491 0.612 ENSMUST00000068987.5
Fam136b-ps
family with sequence similarity 136, member B, pseudogene
chr9_-_108597558 0.589 ENSMUST00000006853.5
P4htm
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
chr19_+_7056731 0.556 ENSMUST00000040261.5
Macrod1
MACRO domain containing 1
chr7_+_118600152 0.554 ENSMUST00000121744.1
Tmc5
transmembrane channel-like gene family 5
chr11_+_66957894 0.541 ENSMUST00000127166.1
9130409J20Rik
RIKEN cDNA 9130409J20 gene
chr13_-_60864373 0.539 ENSMUST00000091569.5
4930486L24Rik
RIKEN cDNA 4930486L24 gene
chr5_-_31048014 0.533 ENSMUST00000137223.1
Slc5a6
solute carrier family 5 (sodium-dependent vitamin transporter), member 6
chr7_+_28756138 0.520 ENSMUST00000178767.1
Gm6537
predicted gene 6537
chr15_-_99087817 0.517 ENSMUST00000064462.3
C1ql4
complement component 1, q subcomponent-like 4
chr11_+_82911253 0.517 ENSMUST00000164945.1
ENSMUST00000018989.7
Unc45b

unc-45 homolog B (C. elegans)

chr7_-_13054514 0.509 ENSMUST00000182087.1
Mzf1
myeloid zinc finger 1
chr8_+_22283441 0.500 ENSMUST00000077194.1
Tpte
transmembrane phosphatase with tensin homology
chr4_+_155839675 0.466 ENSMUST00000141883.1
Mxra8
matrix-remodelling associated 8
chr4_-_64046925 0.461 ENSMUST00000107377.3
Tnc
tenascin C
chr1_+_20951666 0.431 ENSMUST00000038447.4
Efhc1
EF-hand domain (C-terminal) containing 1
chr11_-_118355496 0.423 ENSMUST00000017610.3
Timp2
tissue inhibitor of metalloproteinase 2
chr14_-_33185066 0.423 ENSMUST00000061753.8
ENSMUST00000130509.2
Wdfy4

WD repeat and FYVE domain containing 4

chr9_+_123021315 0.422 ENSMUST00000084733.5
Tmem42
transmembrane protein 42
chr17_-_27513341 0.415 ENSMUST00000118161.1
Grm4
glutamate receptor, metabotropic 4
chr9_-_108305941 0.407 ENSMUST00000044725.7
Tcta
T cell leukemia translocation altered gene
chr8_-_105295934 0.401 ENSMUST00000057855.3
Exoc3l
exocyst complex component 3-like
chr11_-_96916448 0.385 ENSMUST00000103152.4
Cdk5rap3
CDK5 regulatory subunit associated protein 3
chr10_+_112083345 0.381 ENSMUST00000148897.1
ENSMUST00000020434.3
Glipr1l2

GLI pathogenesis-related 1 like 2

chr16_-_44332925 0.364 ENSMUST00000136381.1
Sidt1
SID1 transmembrane family, member 1
chr11_-_103344651 0.359 ENSMUST00000041385.7
Arhgap27
Rho GTPase activating protein 27
chr3_-_141931523 0.342 ENSMUST00000106232.1
Bmpr1b
bone morphogenetic protein receptor, type 1B
chr11_+_118443471 0.331 ENSMUST00000133558.1
C1qtnf1
C1q and tumor necrosis factor related protein 1
chr11_-_59079710 0.318 ENSMUST00000133040.1
Obscn
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
chr9_-_44735189 0.311 ENSMUST00000034611.8
Phldb1
pleckstrin homology-like domain, family B, member 1
chr5_+_134099704 0.304 ENSMUST00000016088.8
Gatsl2
GATS protein-like 2
chr8_-_120177440 0.278 ENSMUST00000048786.6
Fam92b
family with sequence similarity 92, member B
chr15_-_76616841 0.274 ENSMUST00000073428.5
Slc39a4
solute carrier family 39 (zinc transporter), member 4
chr8_-_79248537 0.271 ENSMUST00000034109.4
1700011L22Rik
RIKEN cDNA 1700011L22 gene
chr12_+_78691516 0.264 ENSMUST00000077968.4
Fam71d
family with sequence similarity 71, member D
chr11_-_96916407 0.260 ENSMUST00000130774.1
Cdk5rap3
CDK5 regulatory subunit associated protein 3
chr7_-_99182681 0.256 ENSMUST00000033001.4
Dgat2
diacylglycerol O-acyltransferase 2
chr2_+_71981184 0.244 ENSMUST00000090826.5
ENSMUST00000102698.3
Rapgef4

Rap guanine nucleotide exchange factor (GEF) 4

chr8_+_70863127 0.221 ENSMUST00000050921.2
A230052G05Rik
RIKEN cDNA A230052G05 gene
chr7_-_25718976 0.217 ENSMUST00000002683.2
Ccdc97
coiled-coil domain containing 97
chr6_-_5256226 0.215 ENSMUST00000125686.1
ENSMUST00000031773.2
Pon3

paraoxonase 3

chr4_+_152297205 0.207 ENSMUST00000048892.7
Icmt
isoprenylcysteine carboxyl methyltransferase
chr11_+_49247462 0.195 ENSMUST00000109194.1
Mgat1
mannoside acetylglucosaminyltransferase 1
chrX_+_101383726 0.189 ENSMUST00000119190.1
Gjb1
gap junction protein, beta 1
chr11_-_96916366 0.186 ENSMUST00000144731.1
ENSMUST00000127048.1
Cdk5rap3

CDK5 regulatory subunit associated protein 3

chr17_+_47769191 0.166 ENSMUST00000160373.1
ENSMUST00000159641.1
Tfeb

transcription factor EB

chr15_-_79774408 0.153 ENSMUST00000023055.6
Dnal4
dynein, axonemal, light chain 4
chr18_+_37477768 0.146 ENSMUST00000051442.5
Pcdhb16
protocadherin beta 16
chr9_+_106477269 0.142 ENSMUST00000047721.8
Rrp9
RRP9, small subunit (SSU) processome component, homolog (yeast)
chr1_-_171607321 0.137 ENSMUST00000111277.1
ENSMUST00000004827.7
Ly9

lymphocyte antigen 9

chr1_+_92910805 0.129 ENSMUST00000179711.1
Rnpepl1
arginyl aminopeptidase (aminopeptidase B)-like 1
chr15_-_79774383 0.127 ENSMUST00000069877.5
Dnal4
dynein, axonemal, light chain 4
chr15_-_98004695 0.102 ENSMUST00000023123.8
Col2a1
collagen, type II, alpha 1
chr11_-_70322520 0.097 ENSMUST00000019051.2
Alox12e
arachidonate lipoxygenase, epidermal
chr11_-_100441058 0.091 ENSMUST00000107399.2
ENSMUST00000092688.5
Nt5c3b

5'-nucleotidase, cytosolic IIIB

chr10_+_88201158 0.088 ENSMUST00000171151.2
Ccdc53
coiled-coil domain containing 53
chr15_-_98004634 0.083 ENSMUST00000131560.1
ENSMUST00000088355.5
Col2a1

collagen, type II, alpha 1

chr9_-_106476372 0.066 ENSMUST00000123555.1
ENSMUST00000125850.1
Parp3

poly (ADP-ribose) polymerase family, member 3

chr7_-_4532419 0.063 ENSMUST00000094897.4
Dnaaf3
dynein, axonemal assembly factor 3
chr11_+_50131342 0.062 ENSMUST00000093138.6
ENSMUST00000101270.4
Tbc1d9b

TBC1 domain family, member 9B

chr11_+_66956620 0.052 ENSMUST00000150220.1
9130409J20Rik
RIKEN cDNA 9130409J20 gene
chr6_+_83078339 0.040 ENSMUST00000165164.2
ENSMUST00000092614.2
Pcgf1

polycomb group ring finger 1

chr19_-_7241216 0.040 ENSMUST00000025675.9
Naa40
N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog (S. cerevisiae)
chrY_-_40391443 0.035 ENSMUST00000178865.1
Gm21801
predicted gene, 21801
chrY_-_40457264 0.035 ENSMUST00000178452.1
Gm21914
predicted gene, 21914
chr4_-_12087912 0.030 ENSMUST00000050686.3
Tmem67
transmembrane protein 67
chr1_-_171607378 0.026 ENSMUST00000068878.7
Ly9
lymphocyte antigen 9
chr10_+_79034723 0.023 ENSMUST00000082244.2
Olfr57
olfactory receptor 57
chrY_-_31736484 0.013 ENSMUST00000177888.1
Gm21562
predicted gene, 21562
chrY_+_32221125 0.013 ENSMUST00000179646.1
Gm21821
predicted gene, 21821
chrY_-_32779761 0.013 ENSMUST00000178249.1
Gm21599
predicted gene, 21599
chrY_+_32159845 0.013 ENSMUST00000178692.1
Gm21723
predicted gene, 21723
chrY_-_31802731 0.013 ENSMUST00000180134.1
Gm21572
predicted gene, 21572
chrY_+_32283545 0.013 ENSMUST00000177552.1
Gm21842
predicted gene, 21842
chrY_-_30906508 0.013 ENSMUST00000177925.1
Gm21539
predicted gene, 21539
chrY_-_33636191 0.013 ENSMUST00000177791.1
Gm21626
predicted gene, 21626
chrY_-_33702857 0.013 ENSMUST00000178941.1
Gm21633
predicted gene, 21633
chr11_+_70017085 0.009 ENSMUST00000108589.2
Dlg4
discs, large homolog 4 (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 7.3 GO:0061402 positive regulation of transcription from RNA polymerase II promoter in response to acidic pH(GO:0061402)
1.0 3.0 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
0.7 109.6 GO:0007586 digestion(GO:0007586)
0.6 1.9 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.5 1.4 GO:2000547 lymphocyte migration into lymphoid organs(GO:0097021) positive regulation of thymocyte migration(GO:2000412) regulation of dendritic cell dendrite assembly(GO:2000547)
0.5 1.4 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.4 0.8 GO:0010980 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.4 1.5 GO:0006069 ethanol oxidation(GO:0006069)
0.3 1.0 GO:0042222 interleukin-1 biosynthetic process(GO:0042222)
0.3 1.2 GO:0034760 negative regulation of iron ion transport(GO:0034757) negative regulation of iron ion transmembrane transport(GO:0034760)
0.2 0.7 GO:1990166 protein localization to site of double-strand break(GO:1990166)
0.2 15.0 GO:0031638 zymogen activation(GO:0031638)
0.1 1.1 GO:0006004 fucose metabolic process(GO:0006004)
0.1 0.9 GO:0015886 heme transport(GO:0015886) methotrexate transport(GO:0051958)
0.1 0.5 GO:0060857 establishment of glial blood-brain barrier(GO:0060857)
0.1 0.5 GO:0014012 peripheral nervous system axon regeneration(GO:0014012) bud outgrowth involved in lung branching(GO:0060447)
0.1 0.8 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.1 0.8 GO:0071569 protein ufmylation(GO:0071569)
0.1 0.3 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.1 0.4 GO:0072675 osteoclast fusion(GO:0072675)
0.1 0.2 GO:1904457 positive regulation of neuronal action potential(GO:1904457)
0.1 0.6 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.1 0.2 GO:0009698 phenylpropanoid metabolic process(GO:0009698) coumarin metabolic process(GO:0009804)
0.1 0.3 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.1 0.5 GO:0051182 coenzyme transport(GO:0051182)
0.1 0.4 GO:1905049 negative regulation of metallopeptidase activity(GO:1905049)
0.1 1.4 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.1 1.0 GO:0032825 positive regulation of natural killer cell differentiation(GO:0032825)
0.1 0.2 GO:0006481 C-terminal protein methylation(GO:0006481)
0.0 0.2 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 1.0 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0 6.4 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.2 GO:0009816 defense response, incompatible interaction(GO:0009814) defense response to bacterium, incompatible interaction(GO:0009816) regulation of defense response to bacterium, incompatible interaction(GO:1902477)
0.0 0.4 GO:0033227 dsRNA transport(GO:0033227)
0.0 3.4 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.3 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0 1.0 GO:0071711 basement membrane organization(GO:0071711)
0.0 0.3 GO:0035356 cellular triglyceride homeostasis(GO:0035356)
0.0 17.8 GO:0006887 exocytosis(GO:0006887) vesicle fusion to plasma membrane(GO:0099500) exocytic process(GO:0140029)
0.0 0.4 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.3 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.3 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.8 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.2 GO:0072540 T-helper 17 cell lineage commitment(GO:0072540)
0.0 0.2 GO:0060174 limb bud formation(GO:0060174)
0.0 0.8 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.0 0.8 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 1.2 GO:0048663 neuron fate commitment(GO:0048663)
0.0 0.1 GO:0019372 lipoxygenase pathway(GO:0019372)
0.0 0.6 GO:0045646 regulation of erythrocyte differentiation(GO:0045646)
0.0 0.2 GO:0015865 purine nucleotide transport(GO:0015865) purine ribonucleotide transport(GO:0015868)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 15.5 GO:0042589 zymogen granule membrane(GO:0042589)
0.2 18.8 GO:0030667 secretory granule membrane(GO:0030667)
0.1 16.8 GO:0072562 blood microparticle(GO:0072562)
0.1 0.3 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.2 GO:0044316 cone cell pedicle(GO:0044316)
0.0 0.4 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.8 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.1 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 3.4 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 1.4 GO:0031526 brush border membrane(GO:0031526)
0.0 0.3 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 102.3 GO:0005615 extracellular space(GO:0005615)
0.0 0.3 GO:0045180 basal cortex(GO:0045180)
0.0 0.4 GO:0000145 exocyst(GO:0000145)
0.0 0.7 GO:0090734 site of double-strand break(GO:0035861) site of DNA damage(GO:0090734)
0.0 2.1 GO:0016324 apical plasma membrane(GO:0016324)
0.0 1.7 GO:0031012 extracellular matrix(GO:0031012)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0052593 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.5 1.5 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.3 111.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.3 1.1 GO:0042806 fucose binding(GO:0042806)
0.3 1.4 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.3 2.1 GO:0005499 vitamin D binding(GO:0005499)
0.2 5.4 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.2 0.9 GO:0015232 heme transporter activity(GO:0015232)
0.2 0.8 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.2 0.8 GO:0004092 carnitine O-acetyltransferase activity(GO:0004092)
0.1 1.4 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.1 0.3 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.1 0.7 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.1 0.8 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.2 GO:0004063 aryldialkylphosphatase activity(GO:0004063)
0.1 0.4 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1 0.4 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.1 0.5 GO:0045545 syndecan binding(GO:0045545)
0.1 0.2 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.0 3.4 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.2 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.5 GO:0090482 vitamin transmembrane transporter activity(GO:0090482)
0.0 0.8 GO:0017166 vinculin binding(GO:0017166)
0.0 0.8 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.8 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.6 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.0 0.5 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.3 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.7 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.1 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.0 0.3 GO:0031432 titin binding(GO:0031432)
0.0 0.1 GO:0034511 U3 snoRNA binding(GO:0034511)
0.0 1.2 GO:0005507 copper ion binding(GO:0005507)
0.0 2.9 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.0 0.2 GO:0005243 gap junction channel activity(GO:0005243)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 7.3 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 23.9 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 3.4 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.0 1.7 PID_INTEGRIN1_PATHWAY Beta1 integrin cell surface interactions
0.0 1.4 PID_IL2_1PATHWAY IL2-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 26.1 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.6 7.3 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM Genes involved in Abacavir transport and metabolism
0.1 3.4 REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.5 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 1.4 REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING Genes involved in Growth hormone receptor signaling
0.0 1.4 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.8 REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.8 REACTOME_PEROXISOMAL_LIPID_METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.8 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.4 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.9 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.3 REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.3 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 0.3 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP