Motif ID: Rad21_Smc3

Z-value: 1.178

Transcription factors associated with Rad21_Smc3:

Gene SymbolEntrez IDGene Name
Rad21 ENSMUSG00000022314.9 Rad21
Smc3 ENSMUSG00000024974.10 Smc3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Rad21mm10_v2_chr15_-_51991679_51991760-0.876.6e-12Click!
Smc3mm10_v2_chr19_+_53600377_53600435-0.791.1e-08Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Rad21_Smc3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_+_45069137 9.578 ENSMUST00000067984.7
Mtnr1a
melatonin receptor 1A
chr15_+_10314102 8.312 ENSMUST00000127467.1
Prlr
prolactin receptor
chr7_-_19698383 8.295 ENSMUST00000173739.1
Apoe
apolipoprotein E
chr7_-_19698206 8.234 ENSMUST00000172808.1
ENSMUST00000174191.1
Apoe

apolipoprotein E

chr18_-_61911783 7.482 ENSMUST00000049378.8
ENSMUST00000166783.1
Ablim3

actin binding LIM protein family, member 3

chr11_+_72435565 7.278 ENSMUST00000100903.2
Ggt6
gamma-glutamyltransferase 6
chr5_+_30921556 6.915 ENSMUST00000031053.8
Khk
ketohexokinase
chr19_+_42036025 6.764 ENSMUST00000026172.2
Ankrd2
ankyrin repeat domain 2 (stretch responsive muscle)
chr6_+_124570294 6.747 ENSMUST00000184647.1
C1rb
complement component 1, r subcomponent B
chr6_+_124512615 6.572 ENSMUST00000068593.7
C1ra
complement component 1, r subcomponent A
chr5_+_30921825 6.547 ENSMUST00000117435.1
Khk
ketohexokinase
chr1_+_182564994 6.200 ENSMUST00000048941.7
ENSMUST00000168514.1
Capn8

calpain 8

chr8_+_45069374 6.018 ENSMUST00000130141.1
Mtnr1a
melatonin receptor 1A
chr9_+_111439063 5.957 ENSMUST00000111879.3
Dclk3
doublecortin-like kinase 3
chr5_+_30921867 5.772 ENSMUST00000123885.1
Khk
ketohexokinase
chr2_+_31887262 5.665 ENSMUST00000138325.1
ENSMUST00000028187.6
Lamc3

laminin gamma 3

chr6_-_85915653 5.578 ENSMUST00000161198.2
Cml1
camello-like 1
chr4_+_134396320 5.242 ENSMUST00000105869.2
Pafah2
platelet-activating factor acetylhydrolase 2
chr6_-_85915604 5.223 ENSMUST00000174369.1
Cml1
camello-like 1
chr10_-_31445921 5.014 ENSMUST00000000305.5
Tpd52l1
tumor protein D52-like 1
chr5_-_151369172 4.512 ENSMUST00000067770.3
D730045B01Rik
RIKEN cDNA D730045B01 gene
chr11_+_103103051 4.484 ENSMUST00000152971.1
Acbd4
acyl-Coenzyme A binding domain containing 4
chr3_+_135281221 4.317 ENSMUST00000120397.1
ENSMUST00000171974.1
ENSMUST00000029817.7
Bdh2


3-hydroxybutyrate dehydrogenase, type 2


chr1_-_51915968 4.088 ENSMUST00000046390.7
Myo1b
myosin IB
chr7_+_127800604 4.046 ENSMUST00000046863.5
ENSMUST00000106272.1
ENSMUST00000139068.1
Hsd3b7


hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7


chr7_+_127800844 4.011 ENSMUST00000106271.1
ENSMUST00000138432.1
Hsd3b7

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7

chr5_-_130024280 3.944 ENSMUST00000161640.1
ENSMUST00000161884.1
ENSMUST00000161094.1
Asl


argininosuccinate lyase


chr18_-_3281036 3.858 ENSMUST00000049942.6
ENSMUST00000139537.1
ENSMUST00000124747.1
Crem


cAMP responsive element modulator


chr4_-_57143437 3.767 ENSMUST00000095076.3
ENSMUST00000030142.3
Epb4.1l4b

erythrocyte protein band 4.1-like 4b

chr4_-_149307506 3.742 ENSMUST00000055647.8
ENSMUST00000030806.5
ENSMUST00000060537.6
Kif1b


kinesin family member 1B


chr8_+_60506109 3.648 ENSMUST00000079472.2
Aadat
aminoadipate aminotransferase
chr7_-_34655500 3.644 ENSMUST00000032709.1
Kctd15
potassium channel tetramerisation domain containing 15
chr6_+_85915787 3.630 ENSMUST00000149026.1
Tprkb
Tp53rk binding protein
chr5_+_151368683 3.517 ENSMUST00000181114.1
ENSMUST00000181555.1
1700028E10Rik

RIKEN cDNA 1700028E10 gene

chr9_+_100643605 3.432 ENSMUST00000041418.6
Stag1
stromal antigen 1
chr12_-_102704896 3.422 ENSMUST00000178697.1
ENSMUST00000046518.5
Itpk1

inositol 1,3,4-triphosphate 5/6 kinase

chr6_+_85915709 3.407 ENSMUST00000113751.1
ENSMUST00000113753.1
ENSMUST00000113752.1
ENSMUST00000067137.7
Tprkb



Tp53rk binding protein



chr7_+_64501687 3.371 ENSMUST00000032732.8
Apba2
amyloid beta (A4) precursor protein-binding, family A, member 2
chr2_-_166155272 3.323 ENSMUST00000088086.3
Sulf2
sulfatase 2
chr4_-_114908892 3.268 ENSMUST00000068654.3
Foxd2
forkhead box D2
chr2_+_152669461 3.262 ENSMUST00000125366.1
ENSMUST00000109825.1
ENSMUST00000089059.2
ENSMUST00000079247.3
H13



histocompatibility 13



chr2_+_25428699 3.210 ENSMUST00000102919.3
Abca2
ATP-binding cassette, sub-family A (ABC1), member 2
chr4_+_100095791 3.131 ENSMUST00000039630.5
Ror1
receptor tyrosine kinase-like orphan receptor 1
chr10_+_29313164 3.117 ENSMUST00000160399.1
Echdc1
enoyl Coenzyme A hydratase domain containing 1
chr2_-_173119402 3.107 ENSMUST00000094287.3
ENSMUST00000179693.1
Ctcfl

CCCTC-binding factor (zinc finger protein)-like

chr7_+_64502090 2.973 ENSMUST00000137732.1
Apba2
amyloid beta (A4) precursor protein-binding, family A, member 2
chr14_+_65666394 2.941 ENSMUST00000022610.8
Scara5
scavenger receptor class A, member 5 (putative)
chr3_+_118562129 2.935 ENSMUST00000039177.7
Dpyd
dihydropyrimidine dehydrogenase
chr4_+_41762309 2.913 ENSMUST00000108042.2
Il11ra1
interleukin 11 receptor, alpha chain 1
chr10_+_29313500 2.911 ENSMUST00000020034.4
Echdc1
enoyl Coenzyme A hydratase domain containing 1
chr10_+_29313227 2.871 ENSMUST00000161605.1
Echdc1
enoyl Coenzyme A hydratase domain containing 1
chr19_-_28963863 2.856 ENSMUST00000161813.1
4430402I18Rik
RIKEN cDNA 4430402I18 gene
chr2_+_58567360 2.843 ENSMUST00000071543.5
Upp2
uridine phosphorylase 2
chr7_+_64501949 2.836 ENSMUST00000138829.1
Apba2
amyloid beta (A4) precursor protein-binding, family A, member 2
chr7_+_35119285 2.750 ENSMUST00000042985.9
Cebpa
CCAAT/enhancer binding protein (C/EBP), alpha
chr3_-_63929376 2.741 ENSMUST00000061706.6
E130311K13Rik
RIKEN cDNA E130311K13 gene
chr16_+_18052860 2.739 ENSMUST00000143343.1
Dgcr6
DiGeorge syndrome critical region gene 6
chr7_-_127935429 2.732 ENSMUST00000141385.1
ENSMUST00000156152.1
Prss36

protease, serine, 36

chr17_+_34204080 2.682 ENSMUST00000138491.1
Tap2
transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
chr7_-_19749464 2.669 ENSMUST00000075447.7
ENSMUST00000108450.3
Pvrl2

poliovirus receptor-related 2

chr5_-_25100624 2.651 ENSMUST00000030784.7
Prkag2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chrX_-_44790146 2.598 ENSMUST00000115056.1
Dcaf12l1
DDB1 and CUL4 associated factor 12-like 1
chr13_+_51100810 2.562 ENSMUST00000095797.5
Spin1
spindlin 1
chr19_+_5878622 2.553 ENSMUST00000136833.1
ENSMUST00000141362.1
Slc25a45

solute carrier family 25, member 45

chr13_+_64248649 2.541 ENSMUST00000181403.1
1810034E14Rik
RIKEN cDNA 1810034E14 gene
chr9_+_100643755 2.530 ENSMUST00000133388.1
Stag1
stromal antigen 1
chr9_-_107710475 2.524 ENSMUST00000080560.3
Sema3f
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr4_-_141618238 2.517 ENSMUST00000053263.8
Tmem82
transmembrane protein 82
chr18_+_12643329 2.499 ENSMUST00000025294.7
Ttc39c
tetratricopeptide repeat domain 39C
chr8_+_119446719 2.491 ENSMUST00000098363.3
Necab2
N-terminal EF-hand calcium binding protein 2
chr13_-_35027077 2.478 ENSMUST00000170538.1
ENSMUST00000163280.1
Eci2

enoyl-Coenzyme A delta isomerase 2

chr7_+_16309577 2.475 ENSMUST00000002152.6
Bbc3
BCL2 binding component 3
chr4_+_122995944 2.469 ENSMUST00000106252.2
Mycl
v-myc myelocytomatosis viral oncogene homolog, lung carcinoma derived (avian)
chrX_-_44790179 2.464 ENSMUST00000060481.2
Dcaf12l1
DDB1 and CUL4 associated factor 12-like 1
chr8_-_69890967 2.454 ENSMUST00000152938.1
Yjefn3
YjeF N-terminal domain containing 3
chr9_+_100643448 2.453 ENSMUST00000146312.1
ENSMUST00000129269.1
Stag1

stromal antigen 1

chr3_+_54735536 2.451 ENSMUST00000044567.3
Alg5
asparagine-linked glycosylation 5 (dolichyl-phosphate beta-glucosyltransferase)
chr2_+_70661556 2.449 ENSMUST00000112201.1
ENSMUST00000028509.4
ENSMUST00000133432.1
ENSMUST00000112205.1
Gorasp2



golgi reassembly stacking protein 2



chr9_+_45906513 2.447 ENSMUST00000039059.6
Pcsk7
proprotein convertase subtilisin/kexin type 7
chr8_+_22192800 2.447 ENSMUST00000033866.8
Vps36
vacuolar protein sorting 36 (yeast)
chr10_-_128409632 2.377 ENSMUST00000172348.1
ENSMUST00000166608.1
ENSMUST00000164199.1
ENSMUST00000171370.1
ENSMUST00000026439.7
Nabp2




nucleic acid binding protein 2




chr7_+_44896125 2.374 ENSMUST00000166552.1
ENSMUST00000168207.1
Fuz

fuzzy homolog (Drosophila)

chr19_+_5877794 2.374 ENSMUST00000145200.1
ENSMUST00000025732.7
ENSMUST00000125114.1
ENSMUST00000155697.1
Slc25a45



solute carrier family 25, member 45



chr4_+_41755210 2.272 ENSMUST00000108038.1
ENSMUST00000084695.4
Galt

galactose-1-phosphate uridyl transferase

chrX_-_140600497 2.268 ENSMUST00000112996.2
Tsc22d3
TSC22 domain family, member 3
chr15_-_76232554 2.215 ENSMUST00000166428.1
Plec
plectin
chr14_-_70520254 2.184 ENSMUST00000022693.7
Bmp1
bone morphogenetic protein 1
chr7_+_16310412 2.178 ENSMUST00000136781.1
Bbc3
BCL2 binding component 3
chr1_+_16105774 2.168 ENSMUST00000027053.7
Rdh10
retinol dehydrogenase 10 (all-trans)
chr14_+_65666430 2.155 ENSMUST00000069226.6
Scara5
scavenger receptor class A, member 5 (putative)
chr10_-_10558199 2.146 ENSMUST00000019974.3
Rab32
RAB32, member RAS oncogene family
chr18_-_3337467 2.136 ENSMUST00000154135.1
Crem
cAMP responsive element modulator
chr11_-_109298121 2.135 ENSMUST00000020920.3
Rgs9
regulator of G-protein signaling 9
chr15_-_77399086 2.134 ENSMUST00000175919.1
ENSMUST00000176074.1
Apol7a

apolipoprotein L 7a

chr19_+_5406815 2.132 ENSMUST00000174412.1
ENSMUST00000153017.2
4930481A15Rik

RIKEN cDNA 4930481A15 gene

chr15_+_99099412 2.118 ENSMUST00000061295.6
Dnajc22
DnaJ (Hsp40) homolog, subfamily C, member 22
chr1_+_191575721 2.059 ENSMUST00000045450.5
Ints7
integrator complex subunit 7
chr19_+_6418731 2.044 ENSMUST00000113462.1
ENSMUST00000077182.6
ENSMUST00000113461.1
Nrxn2


neurexin II


chr14_+_77036746 2.011 ENSMUST00000048208.3
ENSMUST00000095625.4
Ccdc122

coiled-coil domain containing 122

chr18_-_3337614 1.988 ENSMUST00000150235.1
ENSMUST00000154470.1
Crem

cAMP responsive element modulator

chr14_+_52810934 1.977 ENSMUST00000103646.3
Trav10d
T cell receptor alpha variable 10D
chr2_-_65567505 1.957 ENSMUST00000100069.2
Scn3a
sodium channel, voltage-gated, type III, alpha
chr9_-_31211805 1.931 ENSMUST00000072634.7
ENSMUST00000079758.7
Aplp2

amyloid beta (A4) precursor-like protein 2

chr11_+_104231390 1.923 ENSMUST00000106992.3
Mapt
microtubule-associated protein tau
chr8_+_111536492 1.920 ENSMUST00000168428.1
ENSMUST00000171182.1
Znrf1

zinc and ring finger 1

chr18_-_37935378 1.919 ENSMUST00000025337.7
Diap1
diaphanous homolog 1 (Drosophila)
chr6_-_129237948 1.911 ENSMUST00000181238.1
ENSMUST00000180379.1
2310001H17Rik

RIKEN cDNA 2310001H17 gene

chr10_-_75773350 1.894 ENSMUST00000001716.7
Ddt
D-dopachrome tautomerase
chr19_-_47464406 1.891 ENSMUST00000111800.2
ENSMUST00000081619.2
Sh3pxd2a

SH3 and PX domains 2A

chr18_-_37935403 1.885 ENSMUST00000080033.6
ENSMUST00000115631.1
Diap1

diaphanous homolog 1 (Drosophila)

chr1_+_194976342 1.871 ENSMUST00000181226.1
ENSMUST00000181947.1
A330023F24Rik

RIKEN cDNA A330023F24 gene

chr14_+_52844465 1.869 ENSMUST00000181360.1
ENSMUST00000183652.1
Trav12d-1

T cell receptor alpha variable 12D-1

chr4_-_45530330 1.864 ENSMUST00000061986.5
Shb
src homology 2 domain-containing transforming protein B
chr18_-_37935429 1.852 ENSMUST00000115634.1
Diap1
diaphanous homolog 1 (Drosophila)
chr8_+_71371283 1.839 ENSMUST00000110051.1
ENSMUST00000002469.8
ENSMUST00000110052.1
Ocel1


occludin/ELL domain containing 1


chr1_+_21218575 1.839 ENSMUST00000027065.5
ENSMUST00000027064.7
Tmem14a

transmembrane protein 14A

chr1_-_134234492 1.833 ENSMUST00000169927.1
Adora1
adenosine A1 receptor
chr2_-_73386396 1.830 ENSMUST00000112044.1
ENSMUST00000112043.1
ENSMUST00000076463.5
Gpr155


G protein-coupled receptor 155


chr11_-_116138862 1.826 ENSMUST00000106439.1
Mrpl38
mitochondrial ribosomal protein L38
chr7_+_44896077 1.801 ENSMUST00000071207.7
ENSMUST00000166849.1
ENSMUST00000168712.1
ENSMUST00000168389.1
Fuz



fuzzy homolog (Drosophila)



chr2_+_167688915 1.779 ENSMUST00000070642.3
Cebpb
CCAAT/enhancer binding protein (C/EBP), beta
chr4_-_89311021 1.765 ENSMUST00000097981.4
Cdkn2b
cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
chr2_-_66256576 1.759 ENSMUST00000125446.2
ENSMUST00000102718.3
Ttc21b

tetratricopeptide repeat domain 21B

chr8_+_87472805 1.757 ENSMUST00000180700.2
ENSMUST00000182174.1
ENSMUST00000181159.1
Gm2694


predicted gene 2694


chr10_-_78043580 1.749 ENSMUST00000145975.1
ENSMUST00000130972.1
ENSMUST00000128241.1
ENSMUST00000155021.1
ENSMUST00000140636.1
ENSMUST00000148469.1
ENSMUST00000019257.8
ENSMUST00000105395.2
ENSMUST00000156417.1
ENSMUST00000105396.2
ENSMUST00000154374.1
Aire










autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy)










chr1_-_150393024 1.736 ENSMUST00000097546.2
ENSMUST00000111913.2
BC003331

cDNA sequence BC003331

chr11_+_118443471 1.718 ENSMUST00000133558.1
C1qtnf1
C1q and tumor necrosis factor related protein 1
chr2_+_38998302 1.717 ENSMUST00000112872.1
Wdr38
WD repeat domain 38
chr18_-_3337539 1.705 ENSMUST00000142690.1
ENSMUST00000025069.4
ENSMUST00000082141.5
ENSMUST00000165086.1
ENSMUST00000149803.1
Crem




cAMP responsive element modulator




chr6_+_85154992 1.702 ENSMUST00000089584.5
Spr-ps1
sepiapterin reductase pseudogene 1
chr11_-_53470479 1.700 ENSMUST00000057722.2
Gm9837
predicted gene 9837
chr18_-_56562261 1.693 ENSMUST00000066208.6
ENSMUST00000172734.1
Aldh7a1

aldehyde dehydrogenase family 7, member A1

chr18_-_56562187 1.687 ENSMUST00000171844.2
Aldh7a1
aldehyde dehydrogenase family 7, member A1
chr5_+_42067960 1.681 ENSMUST00000087332.4
Gm16223
predicted gene 16223
chr7_-_141437829 1.676 ENSMUST00000019226.7
Slc25a22
solute carrier family 25 (mitochondrial carrier, glutamate), member 22
chr1_+_58113136 1.669 ENSMUST00000040999.7
Aox3
aldehyde oxidase 3
chr9_-_50528641 1.652 ENSMUST00000034570.5
Pts
6-pyruvoyl-tetrahydropterin synthase
chr6_-_85137743 1.652 ENSMUST00000174769.1
ENSMUST00000174286.1
ENSMUST00000045986.7
Spr


sepiapterin reductase


chr3_-_5576111 1.649 ENSMUST00000165309.1
ENSMUST00000164828.1
ENSMUST00000071280.5
Pex2


peroxisomal biogenesis factor 2


chr8_+_87472838 1.646 ENSMUST00000180806.2
Gm2694
predicted gene 2694
chr9_+_44772909 1.631 ENSMUST00000002099.3
Ift46
intraflagellar transport 46
chr9_+_44772951 1.627 ENSMUST00000128150.1
Ift46
intraflagellar transport 46
chr11_+_84179852 1.621 ENSMUST00000136463.2
Acaca
acetyl-Coenzyme A carboxylase alpha
chr14_+_52769753 1.600 ENSMUST00000178768.2
Trav7d-4
T cell receptor alpha variable 7D-4
chr3_-_121171678 1.590 ENSMUST00000170781.1
ENSMUST00000039761.5
ENSMUST00000106467.1
ENSMUST00000106466.3
ENSMUST00000164925.2
Rwdd3




RWD domain containing 3




chr2_-_166155624 1.586 ENSMUST00000109249.2
Sulf2
sulfatase 2
chr14_-_21748610 1.582 ENSMUST00000075040.2
ENSMUST00000183943.1
Dusp13

dual specificity phosphatase 13

chr7_-_141437587 1.580 ENSMUST00000172654.1
ENSMUST00000106006.1
Slc25a22

solute carrier family 25 (mitochondrial carrier, glutamate), member 22

chr13_-_41220395 1.578 ENSMUST00000021793.7
Elovl2
elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 2
chr3_-_5576233 1.570 ENSMUST00000059021.4
Pex2
peroxisomal biogenesis factor 2
chr7_-_74554726 1.564 ENSMUST00000107453.1
Slco3a1
solute carrier organic anion transporter family, member 3a1
chr11_+_105975204 1.562 ENSMUST00000001964.7
Ace
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
chr13_-_8871751 1.551 ENSMUST00000175958.1
Wdr37
WD repeat domain 37
chr18_-_56562215 1.546 ENSMUST00000170309.1
Aldh7a1
aldehyde dehydrogenase family 7, member A1
chr5_+_120649188 1.535 ENSMUST00000156722.1
Rasal1
RAS protein activator like 1 (GAP1 like)
chr13_+_54621801 1.532 ENSMUST00000026991.9
ENSMUST00000137413.1
ENSMUST00000135232.1
ENSMUST00000124752.1
Faf2



Fas associated factor family member 2



chr9_+_110333340 1.532 ENSMUST00000098350.3
Scap
SREBF chaperone
chr11_-_82890541 1.529 ENSMUST00000092844.6
ENSMUST00000021033.9
ENSMUST00000018985.8
Rad51d


RAD51 homolog D


chr2_-_112368021 1.523 ENSMUST00000028551.3
Emc4
ER membrane protein complex subunit 4
chr16_-_94313556 1.505 ENSMUST00000163193.1
Hlcs
holocarboxylase synthetase (biotin- [propriony-Coenzyme A-carboxylase (ATP-hydrolysing)] ligase)
chr6_+_108783059 1.494 ENSMUST00000032196.6
Arl8b
ADP-ribosylation factor-like 8B
chr1_-_150392719 1.476 ENSMUST00000006167.6
ENSMUST00000094477.2
ENSMUST00000097547.3
BC003331


cDNA sequence BC003331


chr14_+_52824340 1.476 ENSMUST00000103648.2
Trav11d
T cell receptor alpha variable 11D
chr15_-_76511951 1.468 ENSMUST00000023214.4
Dgat1
diacylglycerol O-acyltransferase 1
chr12_+_8313425 1.467 ENSMUST00000020927.8
Hs1bp3
HCLS1 binding protein 3
chr19_-_10880370 1.462 ENSMUST00000133303.1
Tmem109
transmembrane protein 109
chr14_+_52753367 1.460 ENSMUST00000180717.1
ENSMUST00000183820.1
Trav6d-4

T cell receptor alpha variable 6D-4

chr15_-_99087817 1.458 ENSMUST00000064462.3
C1ql4
complement component 1, q subcomponent-like 4
chr7_-_4524229 1.451 ENSMUST00000154913.1
Tnni3
troponin I, cardiac 3
chr11_+_50131342 1.438 ENSMUST00000093138.6
ENSMUST00000101270.4
Tbc1d9b

TBC1 domain family, member 9B

chr4_-_44072712 1.437 ENSMUST00000102936.2
Gne
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
chr11_+_104231573 1.435 ENSMUST00000132977.1
ENSMUST00000132245.1
ENSMUST00000100347.4
Mapt


microtubule-associated protein tau


chr14_+_53443243 1.427 ENSMUST00000177622.2
Trav7-3
T cell receptor alpha variable 7-3
chr7_+_107209439 1.422 ENSMUST00000098135.1
Rbmxl2
RNA binding motif protein, X-linked-like 2
chr8_-_110168204 1.419 ENSMUST00000003754.6
Calb2
calbindin 2
chr14_+_53461099 1.414 ENSMUST00000181728.1
Trav7-4
T cell receptor alpha variable 7-4
chr13_-_41220162 1.406 ENSMUST00000117096.1
Elovl2
elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 2
chr8_-_87472576 1.399 ENSMUST00000034076.8
Cbln1
cerebellin 1 precursor protein
chr11_+_78178105 1.398 ENSMUST00000147819.1
Tlcd1
TLC domain containing 1
chr9_-_57645561 1.358 ENSMUST00000034863.6
Csk
c-src tyrosine kinase
chr8_-_109962127 1.348 ENSMUST00000001722.7
ENSMUST00000051430.6
Marveld3

MARVEL (membrane-associating) domain containing 3

chr3_-_89160155 1.346 ENSMUST00000029686.3
Hcn3
hyperpolarization-activated, cyclic nucleotide-gated K+ 3
chr17_+_28232723 1.346 ENSMUST00000002320.8
Ppard
peroxisome proliferator activator receptor delta
chr14_-_55758458 1.334 ENSMUST00000001497.7
Cideb
cell death-inducing DNA fragmentation factor, alpha subunit-like effector B
chr18_-_38211957 1.310 ENSMUST00000159405.1
ENSMUST00000160721.1
Pcdh1

protocadherin 1

chr17_-_26090251 1.301 ENSMUST00000040907.6
Decr2
2-4-dienoyl-Coenzyme A reductase 2, peroxisomal
chr14_+_62555737 1.293 ENSMUST00000039064.7
Fam124a
family with sequence similarity 124, member A
chr14_+_53676141 1.290 ENSMUST00000103662.4
Trav9-4
T cell receptor alpha variable 9-4
chr11_+_104231465 1.284 ENSMUST00000145227.1
Mapt
microtubule-associated protein tau
chr1_-_55363462 1.283 ENSMUST00000159398.1
Boll
bol, boule-like (Drosophila)
chr7_+_141455198 1.279 ENSMUST00000164016.1
ENSMUST00000064151.6
ENSMUST00000169665.1
Pnpla2


patatin-like phospholipase domain containing 2


chr18_+_74442500 1.277 ENSMUST00000074157.6
Myo5b
myosin VB
chr19_+_44989073 1.265 ENSMUST00000026225.8
Sema4g
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr11_-_76763550 1.251 ENSMUST00000010536.8
Gosr1
golgi SNAP receptor complex member 1
chr7_-_45136391 1.247 ENSMUST00000146760.1
Flt3l
FMS-like tyrosine kinase 3 ligand
chr9_+_107888129 1.244 ENSMUST00000035202.2
Mon1a
MON1 homolog A (yeast)
chr13_+_117602439 1.236 ENSMUST00000006991.7
Hcn1
hyperpolarization-activated, cyclic nucleotide-gated K+ 1
chr5_+_140331860 1.225 ENSMUST00000071881.3
ENSMUST00000050205.5
ENSMUST00000110827.1
Nudt1


nudix (nucleoside diphosphate linked moiety X)-type motif 1


chr14_+_52792208 1.204 ENSMUST00000178426.2
Trav9d-1
T cell receptor alpha variable 9D-1
chr5_-_66618636 1.200 ENSMUST00000162382.1
ENSMUST00000160870.1
ENSMUST00000087256.5
ENSMUST00000160103.1
ENSMUST00000162349.1
Apbb2




amyloid beta (A4) precursor protein-binding, family B, member 2





Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
5.5 16.5 GO:1905890 cellular response to very-low-density lipoprotein particle stimulus(GO:0090731) negative regulation of presynaptic membrane organization(GO:1901630) regulation of lipid transport across blood brain barrier(GO:1903000) positive regulation of lipid transport across blood brain barrier(GO:1903002) regulation of heparan sulfate binding(GO:1905853) positive regulation of heparan sulfate binding(GO:1905855) regulation of heparan sulfate proteoglycan binding(GO:1905858) positive regulation of heparan sulfate proteoglycan binding(GO:1905860) regulation of cellular response to very-low-density lipoprotein particle stimulus(GO:1905890)
4.8 19.2 GO:0006001 fructose catabolic process(GO:0006001) response to sucrose(GO:0009744) response to disaccharide(GO:0034285) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) glycolytic process through fructose-1-phosphate(GO:0061625)
1.4 4.2 GO:2000314 negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
1.4 8.3 GO:0038161 prolactin signaling pathway(GO:0038161)
1.3 3.9 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450)
1.2 4.9 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
1.2 4.7 GO:1900739 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
1.1 3.3 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
1.0 2.9 GO:0046104 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859) thymidine metabolic process(GO:0046104)
0.9 8.1 GO:0035754 B cell chemotaxis(GO:0035754)
0.9 2.7 GO:0002591 positive regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002591) peptide antigen transport(GO:0046968)
0.8 2.5 GO:0060168 positive regulation of adenosine receptor signaling pathway(GO:0060168) regulation of G-protein coupled receptor internalization(GO:1904020)
0.7 2.9 GO:0038154 interleukin-11-mediated signaling pathway(GO:0038154)
0.7 2.7 GO:0044268 multicellular organismal protein metabolic process(GO:0044268)
0.6 5.8 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.6 15.6 GO:0030828 positive regulation of cGMP biosynthetic process(GO:0030828)
0.6 2.4 GO:0043328 protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.6 1.8 GO:0042323 negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
0.6 1.7 GO:0002458 peripheral T cell tolerance induction(GO:0002458) peripheral tolerance induction(GO:0002465) regulation of thymocyte migration(GO:2000410)
0.6 2.9 GO:0009227 nucleotide-sugar catabolic process(GO:0009227)
0.5 1.6 GO:1902071 positive regulation of cellular response to hypoxia(GO:1900039) regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.5 7.3 GO:0006751 glutathione catabolic process(GO:0006751)
0.5 1.6 GO:2000170 positive regulation of peptidyl-cysteine S-nitrosylation(GO:2000170)
0.5 1.5 GO:1901738 regulation of vitamin A metabolic process(GO:1901738)
0.5 1.9 GO:0046684 response to pyrethroid(GO:0046684)
0.5 1.4 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.4 6.8 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.4 2.5 GO:0097491 trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.4 1.3 GO:0048209 regulation of vesicle targeting, to, from or within Golgi(GO:0048209)
0.4 1.2 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.4 1.2 GO:0046061 dATP catabolic process(GO:0046061)
0.4 1.2 GO:1902559 3'-phosphoadenosine 5'-phosphosulfate transport(GO:0046963) 3'-phospho-5'-adenylyl sulfate transmembrane transport(GO:1902559)
0.4 2.3 GO:0032439 endosome localization(GO:0032439)
0.4 1.1 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.4 2.3 GO:0098964 dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964)
0.4 1.9 GO:0072675 osteoclast fusion(GO:0072675)
0.4 1.1 GO:0044313 protein K6-linked deubiquitination(GO:0044313) protein K27-linked deubiquitination(GO:1990167)
0.4 1.1 GO:0061792 secretory granule maturation(GO:0061792)
0.4 3.3 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729)
0.4 0.7 GO:1904954 canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904954)
0.4 2.2 GO:0060431 primary lung bud formation(GO:0060431)
0.4 1.4 GO:0060598 dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis(GO:0060598)
0.3 5.4 GO:0019184 nonribosomal peptide biosynthetic process(GO:0019184)
0.3 1.7 GO:0009115 xanthine catabolic process(GO:0009115) xanthine metabolic process(GO:0046110)
0.3 3.6 GO:0019441 tryptophan catabolic process(GO:0006569) tryptophan catabolic process to kynurenine(GO:0019441) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218)
0.3 3.2 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.3 3.7 GO:0007270 neuron-neuron synaptic transmission(GO:0007270)
0.3 2.7 GO:0000050 urea cycle(GO:0000050)
0.3 1.5 GO:1903232 melanosome assembly(GO:1903232)
0.3 1.5 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.3 4.1 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.3 3.2 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.3 1.1 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.3 0.8 GO:0021759 globus pallidus development(GO:0021759)
0.3 0.8 GO:1902463 protein localization to cell leading edge(GO:1902463)
0.3 1.4 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.3 1.3 GO:0006776 vitamin A metabolic process(GO:0006776)
0.3 1.0 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.3 1.5 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.3 1.0 GO:0002636 positive regulation of germinal center formation(GO:0002636)
0.2 3.0 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.2 0.7 GO:1904569 regulation of selenocysteine incorporation(GO:1904569)
0.2 1.5 GO:0001980 regulation of systemic arterial blood pressure by ischemic conditions(GO:0001980)
0.2 4.8 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.2 3.3 GO:0006047 UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.2 1.1 GO:1904690 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.2 1.8 GO:0097421 liver regeneration(GO:0097421)
0.2 0.9 GO:0006244 pyrimidine nucleotide catabolic process(GO:0006244) pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.2 1.1 GO:0032364 oxygen homeostasis(GO:0032364)
0.2 1.0 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.2 1.9 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.2 2.5 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.2 10.2 GO:0006958 complement activation, classical pathway(GO:0006958)
0.2 0.8 GO:0099540 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.2 0.8 GO:1902528 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.2 0.6 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.2 1.0 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.2 1.3 GO:0060078 regulation of postsynaptic membrane potential(GO:0060078)
0.2 1.7 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.2 1.5 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.2 11.6 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.2 3.3 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.2 2.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.2 0.5 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.2 4.5 GO:0001539 cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285)
0.2 1.0 GO:0072086 specification of loop of Henle identity(GO:0072086)
0.2 0.6 GO:0070368 positive regulation of hepatocyte differentiation(GO:0070368)
0.2 1.4 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.2 4.6 GO:0034389 lipid particle organization(GO:0034389)
0.1 1.8 GO:0060253 negative regulation of glial cell proliferation(GO:0060253)
0.1 2.1 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.1 0.4 GO:0035990 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.1 0.6 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.1 0.6 GO:1903978 regulation of microglial cell activation(GO:1903978)
0.1 0.3 GO:2000017 positive regulation of determination of dorsal identity(GO:2000017)
0.1 0.6 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.1 0.3 GO:0072268 pattern specification involved in metanephros development(GO:0072268)
0.1 0.4 GO:0015828 tyrosine transport(GO:0015828)
0.1 0.4 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.1 0.7 GO:0002121 inter-male aggressive behavior(GO:0002121)
0.1 1.8 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.1 0.5 GO:0009816 defense response to bacterium, incompatible interaction(GO:0009816) regulation of defense response to bacterium, incompatible interaction(GO:1902477)
0.1 1.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 11.0 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.1 0.6 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.1 0.7 GO:0000429 carbon catabolite regulation of transcription from RNA polymerase II promoter(GO:0000429) carbon catabolite activation of transcription from RNA polymerase II promoter(GO:0000436)
0.1 0.6 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.1 0.8 GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.1 0.7 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.1 3.8 GO:0014002 astrocyte development(GO:0014002)
0.1 4.7 GO:0070207 protein homotrimerization(GO:0070207)
0.1 2.6 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.1 0.3 GO:0043181 vacuolar sequestering(GO:0043181)
0.1 0.5 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.1 0.9 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 3.1 GO:0006349 regulation of gene expression by genetic imprinting(GO:0006349)
0.1 1.2 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.1 1.6 GO:0006857 oligopeptide transport(GO:0006857)
0.1 1.5 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.1 2.1 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.1 0.5 GO:2000360 negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.1 1.1 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 0.5 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.1 2.0 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 0.7 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.1 0.9 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 0.7 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.1 1.9 GO:0001967 suckling behavior(GO:0001967)
0.1 0.3 GO:0061314 Notch signaling involved in heart development(GO:0061314)
0.1 8.4 GO:1903749 positive regulation of establishment of protein localization to mitochondrion(GO:1903749) positive regulation of protein targeting to mitochondrion(GO:1903955)
0.1 1.3 GO:1902414 protein localization to cell junction(GO:1902414)
0.1 0.2 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.1 0.4 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.1 1.1 GO:0098719 sodium ion import across plasma membrane(GO:0098719)
0.1 0.9 GO:0007288 sperm axoneme assembly(GO:0007288)
0.1 2.0 GO:0042297 vocal learning(GO:0042297) imitative learning(GO:0098596)
0.1 1.3 GO:0097202 activation of cysteine-type endopeptidase activity(GO:0097202)
0.1 1.0 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.1 1.6 GO:0070200 establishment of protein localization to telomere(GO:0070200)
0.1 1.0 GO:0043248 proteasome assembly(GO:0043248)
0.1 0.4 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.1 0.6 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.1 2.1 GO:0042438 melanin biosynthetic process(GO:0042438)
0.1 0.7 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.1 0.5 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.1 0.3 GO:0002190 cap-independent translational initiation(GO:0002190)
0.1 0.7 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 0.9 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 0.4 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 0.3 GO:0003273 cell migration involved in endocardial cushion formation(GO:0003273)
0.1 0.7 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.1 1.8 GO:0007143 female meiotic nuclear division(GO:0007143)
0.1 1.8 GO:0035855 megakaryocyte development(GO:0035855)
0.1 0.5 GO:0090261 positive regulation of inclusion body assembly(GO:0090261)
0.1 1.5 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.1 0.2 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.1 0.2 GO:1903028 regulation of opsonization(GO:1903027) positive regulation of opsonization(GO:1903028)
0.1 6.0 GO:1900181 negative regulation of protein localization to nucleus(GO:1900181)
0.1 0.1 GO:0071047 nuclear polyadenylation-dependent mRNA catabolic process(GO:0071042) polyadenylation-dependent mRNA catabolic process(GO:0071047)
0.1 4.2 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.1 2.2 GO:0061036 positive regulation of cartilage development(GO:0061036)
0.1 0.3 GO:0060178 regulation of exocyst localization(GO:0060178)
0.1 0.7 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.1 0.2 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.1 0.8 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.1 0.8 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.1 0.6 GO:0021756 striatum development(GO:0021756)
0.1 0.5 GO:0050957 equilibrioception(GO:0050957)
0.1 0.5 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.2 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.2 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.0 0.9 GO:0044406 adhesion of symbiont to host(GO:0044406)
0.0 0.7 GO:0045351 type I interferon biosynthetic process(GO:0045351)
0.0 0.5 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 6.1 GO:0008033 tRNA processing(GO:0008033)
0.0 0.3 GO:0003352 regulation of cilium movement(GO:0003352) protein polyglutamylation(GO:0018095)
0.0 5.9 GO:0007586 digestion(GO:0007586)
0.0 1.0 GO:0060416 response to growth hormone(GO:0060416)
0.0 2.7 GO:0019217 regulation of fatty acid metabolic process(GO:0019217)
0.0 0.8 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.1 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.0 0.7 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 1.6 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 1.3 GO:0006636 unsaturated fatty acid biosynthetic process(GO:0006636)
0.0 0.3 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 1.2 GO:0033273 response to vitamin(GO:0033273)
0.0 2.8 GO:0009166 nucleotide catabolic process(GO:0009166)
0.0 4.1 GO:0006892 post-Golgi vesicle-mediated transport(GO:0006892)
0.0 0.5 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.1 GO:0045324 late endosome to vacuole transport(GO:0045324)
0.0 9.0 GO:0035264 multicellular organism growth(GO:0035264)
0.0 2.5 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.0 0.2 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.0 1.0 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.4 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.7 GO:0046686 response to cadmium ion(GO:0046686)
0.0 0.9 GO:0030262 apoptotic nuclear changes(GO:0030262)
0.0 0.6 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.3 GO:0050687 negative regulation of defense response to virus(GO:0050687)
0.0 0.9 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.1 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.0 0.2 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.7 GO:0014898 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.0 1.5 GO:0032418 lysosome localization(GO:0032418)
0.0 0.8 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.0 4.4 GO:0016042 lipid catabolic process(GO:0016042)
0.0 0.1 GO:1903214 regulation of protein targeting to mitochondrion(GO:1903214)
0.0 2.4 GO:0007030 Golgi organization(GO:0007030)
0.0 0.6 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.0 0.1 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 1.7 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.1 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.0 0.3 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.4 GO:0046710 GDP metabolic process(GO:0046710)
0.0 0.1 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.8 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.0 1.0 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.2 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.2 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.9 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.0 1.0 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.4 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.0 0.4 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.2 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 1.1 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.1 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.0 0.8 GO:0051028 mRNA transport(GO:0051028)
0.0 1.9 GO:0046330 positive regulation of JNK cascade(GO:0046330)
0.0 1.6 GO:0044070 regulation of anion transport(GO:0044070)
0.0 1.9 GO:0007601 visual perception(GO:0007601)
0.0 0.4 GO:0035329 hippo signaling(GO:0035329)
0.0 0.6 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 0.3 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 2.1 GO:0001764 neuron migration(GO:0001764)
0.0 0.4 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.8 GO:0000725 double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725)
0.0 0.5 GO:0050919 negative chemotaxis(GO:0050919)
0.0 2.0 GO:0016485 protein processing(GO:0016485)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 16.5 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
1.5 4.5 GO:0036488 CHOP-C/EBP complex(GO:0036488)
1.4 7.0 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.8 2.4 GO:0000814 ESCRT II complex(GO:0000814)
0.6 5.8 GO:0045298 tubulin complex(GO:0045298)
0.5 3.3 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.5 2.4 GO:0070876 SOSS complex(GO:0070876)
0.4 3.5 GO:0042825 TAP complex(GO:0042825)
0.4 1.2 GO:0098855 HCN channel complex(GO:0098855)
0.4 2.8 GO:0045098 type III intermediate filament(GO:0045098)
0.3 1.0 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.3 2.1 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009) pigment granule membrane(GO:0090741)
0.3 1.5 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.3 1.2 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.3 1.3 GO:0044316 cone cell pedicle(GO:0044316)
0.3 2.6 GO:0070545 PeBoW complex(GO:0070545)
0.2 3.9 GO:0070852 cell body fiber(GO:0070852)
0.2 1.5 GO:1990584 cardiac Troponin complex(GO:1990584)
0.2 0.7 GO:0016939 kinesin II complex(GO:0016939)
0.2 2.6 GO:0036501 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) UFD1-NPL4 complex(GO:0036501)
0.2 1.1 GO:0097361 CIA complex(GO:0097361)
0.2 1.9 GO:0030991 intraciliary transport particle A(GO:0030991)
0.2 5.8 GO:0030992 intraciliary transport particle B(GO:0030992)
0.2 1.8 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.2 0.5 GO:0060473 cortical granule(GO:0060473)
0.2 3.7 GO:0005797 Golgi medial cisterna(GO:0005797)
0.2 0.5 GO:0034667 integrin alpha3-beta1 complex(GO:0034667)
0.1 4.0 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 1.6 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 0.7 GO:0002142 stereocilia ankle link complex(GO:0002142)
0.1 2.1 GO:0032039 integrator complex(GO:0032039)
0.1 0.5 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.1 1.8 GO:0031209 SCAR complex(GO:0031209)
0.1 0.7 GO:1990131 GATOR1 complex(GO:1990130) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 4.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 2.2 GO:0030056 hemidesmosome(GO:0030056)
0.1 1.8 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 1.3 GO:1990909 Wnt signalosome(GO:1990909)
0.1 2.2 GO:0097225 sperm midpiece(GO:0097225)
0.1 5.3 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 1.5 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 0.3 GO:0048179 activin receptor complex(GO:0048179)
0.1 1.4 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 2.7 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 0.2 GO:0090725 peripheral region of growth cone(GO:0090725)
0.1 5.2 GO:0000791 euchromatin(GO:0000791)
0.1 2.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 1.5 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 1.0 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 1.5 GO:0005652 nuclear lamina(GO:0005652)
0.1 0.9 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
0.1 8.1 GO:0008021 synaptic vesicle(GO:0008021)
0.1 9.4 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 1.0 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.9 GO:1990635 proximal dendrite(GO:1990635)
0.1 0.5 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 4.2 GO:1904115 axon cytoplasm(GO:1904115)
0.1 0.5 GO:0031595 nuclear proteasome complex(GO:0031595)
0.1 0.8 GO:0005869 dynactin complex(GO:0005869)
0.1 3.4 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 0.8 GO:0016589 NURF complex(GO:0016589)
0.1 0.6 GO:0043083 synaptic cleft(GO:0043083)
0.1 0.2 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.1 0.4 GO:0005838 proteasome regulatory particle(GO:0005838)
0.1 0.9 GO:0030008 TRAPP complex(GO:0030008)
0.1 1.1 GO:0016580 Sin3 complex(GO:0016580)
0.0 2.5 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.8 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 2.3 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 7.3 GO:0072562 blood microparticle(GO:0072562)
0.0 4.1 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 5.2 GO:0005604 basement membrane(GO:0005604)
0.0 2.7 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.4 GO:0070578 RISC-loading complex(GO:0070578)
0.0 1.0 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.3 GO:0030914 STAGA complex(GO:0030914)
0.0 0.3 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 17.0 GO:0043235 receptor complex(GO:0043235)
0.0 3.4 GO:0016324 apical plasma membrane(GO:0016324)
0.0 1.9 GO:0042734 presynaptic membrane(GO:0042734)
0.0 1.4 GO:0005921 gap junction(GO:0005921)
0.0 0.1 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 2.3 GO:0005769 early endosome(GO:0005769)
0.0 2.5 GO:0016459 myosin complex(GO:0016459)
0.0 0.7 GO:0002102 podosome(GO:0002102)
0.0 3.7 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.2 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 2.6 GO:0005811 lipid droplet(GO:0005811)
0.0 0.3 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.5 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.1 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.0 0.4 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.5 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.7 GO:0043198 dendritic shaft(GO:0043198)
0.0 1.1 GO:1990391 DNA repair complex(GO:1990391)
0.0 0.6 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 6.5 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 1.3 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 3.3 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 0.8 GO:0032587 ruffle membrane(GO:0032587)
0.0 9.2 GO:0005667 transcription factor complex(GO:0005667)
0.0 1.4 GO:0000932 P-body(GO:0000932)
0.0 0.8 GO:0043679 axon terminus(GO:0043679)
0.0 2.1 GO:0001650 fibrillar center(GO:0001650)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.1 GO:1990246 uniplex complex(GO:1990246)
0.0 1.2 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.4 GO:0043034 costamere(GO:0043034)
0.0 2.2 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
5.5 16.5 GO:0046911 metal chelating activity(GO:0046911)
4.8 19.2 GO:0004454 ketohexokinase activity(GO:0004454) triokinase activity(GO:0050354) fructose-1-phosphate aldolase activity(GO:0061609)
3.1 15.6 GO:0008502 melatonin receptor activity(GO:0008502)
3.0 8.9 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
1.7 8.3 GO:0004925 prolactin receptor activity(GO:0004925)
1.5 4.4 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
1.2 4.9 GO:0008802 betaine-aldehyde dehydrogenase activity(GO:0008802)
1.1 3.4 GO:0051765 inositol tetrakisphosphate kinase activity(GO:0051765)
1.1 6.8 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
1.0 5.1 GO:0070287 ferritin receptor activity(GO:0070287)
1.0 3.9 GO:0016842 amidine-lyase activity(GO:0016842)
1.0 4.9 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.8 5.8 GO:0099609 microtubule lateral binding(GO:0099609)
0.7 2.9 GO:0004921 interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
0.7 2.1 GO:0035651 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.7 3.3 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761)
0.6 2.5 GO:0031687 A2A adenosine receptor binding(GO:0031687)
0.6 7.3 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.6 8.1 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.6 2.8 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.6 2.3 GO:0003978 UDP-glucose 4-epimerase activity(GO:0003978) UTP:galactose-1-phosphate uridylyltransferase activity(GO:0017103)
0.6 1.7 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.5 2.7 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980)
0.5 2.7 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.5 5.2 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.5 1.5 GO:0009374 biotin binding(GO:0009374)
0.5 2.5 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.5 1.5 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.5 1.4 GO:0098973 structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.4 1.3 GO:0016501 prostacyclin receptor activity(GO:0016501)
0.4 1.3 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.4 2.6 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.4 0.8 GO:0046978 TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.4 2.9 GO:0002054 nucleobase binding(GO:0002054)
0.4 3.3 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.4 1.2 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.4 3.2 GO:0043426 MRF binding(GO:0043426)
0.4 1.6 GO:0070573 tripeptidyl-peptidase activity(GO:0008240) bradykinin receptor binding(GO:0031711) metallodipeptidase activity(GO:0070573)
0.4 2.7 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.3 1.7 GO:0016623 aldehyde oxidase activity(GO:0004031) xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726)
0.3 2.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.3 1.5 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.3 1.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.3 0.8 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.3 0.8 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.3 2.6 GO:0035473 lipase binding(GO:0035473)
0.3 3.3 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.2 3.0 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.2 5.9 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.2 1.5 GO:0000150 recombinase activity(GO:0000150)
0.2 1.9 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.2 1.5 GO:0030172 troponin C binding(GO:0030172)
0.2 2.1 GO:0008494 translation activator activity(GO:0008494)
0.2 1.8 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.2 1.6 GO:0015198 oligopeptide transporter activity(GO:0015198)
0.2 0.6 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.2 4.1 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.2 2.1 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.2 2.4 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.2 11.3 GO:0001540 amyloid-beta binding(GO:0001540)
0.2 1.0 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.2 2.7 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013)
0.2 0.5 GO:0070002 glutamic-type peptidase activity(GO:0070002)
0.2 0.6 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.2 2.5 GO:0045499 chemorepellent activity(GO:0045499)
0.2 1.6 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.2 4.2 GO:0008483 transaminase activity(GO:0008483)
0.2 1.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.2 0.6 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.1 0.4 GO:0051747 cytosine C-5 DNA demethylase activity(GO:0051747)
0.1 1.1 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.1 0.4 GO:0005302 L-tyrosine transmembrane transporter activity(GO:0005302)
0.1 0.7 GO:0033142 progesterone receptor binding(GO:0033142)
0.1 0.7 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.1 1.6 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 0.7 GO:0016453 acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453)
0.1 1.8 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 1.8 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 1.4 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 1.1 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 1.0 GO:0004462 hydroxyacylglutathione hydrolase activity(GO:0004416) lactoylglutathione lyase activity(GO:0004462)
0.1 1.8 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.1 3.0 GO:0003954 NADH dehydrogenase activity(GO:0003954)
0.1 0.7 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.1 1.8 GO:0031402 sodium ion binding(GO:0031402)
0.1 0.4 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.1 0.5 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1 0.7 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.1 3.4 GO:0030506 ankyrin binding(GO:0030506)
0.1 0.3 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.1 0.4 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 0.5 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 0.3 GO:0046923 ER retention sequence binding(GO:0046923)
0.1 3.6 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 0.6 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 0.9 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 2.0 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1 19.2 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 0.9 GO:0019966 interleukin-1 binding(GO:0019966)
0.1 2.5 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 0.3 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.1 0.2 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.6 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.0 0.2 GO:0032405 exodeoxyribonuclease III activity(GO:0008853) MutLalpha complex binding(GO:0032405)
0.0 1.6 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.7 GO:0048018 receptor agonist activity(GO:0048018)
0.0 3.1 GO:0019894 kinesin binding(GO:0019894)
0.0 1.8 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 2.0 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 1.0 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.4 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 2.6 GO:0015485 cholesterol binding(GO:0015485)
0.0 1.0 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 2.3 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.3 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 1.7 GO:0045182 translation regulator activity(GO:0045182)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 1.3 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.8 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.8 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.2 GO:0052795 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 1.0 GO:0005109 frizzled binding(GO:0005109)
0.0 7.2 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.0 1.9 GO:0001784 phosphotyrosine residue binding(GO:0001784)
0.0 0.2 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.0 1.9 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.4 GO:0035198 miRNA binding(GO:0035198)
0.0 0.9 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714) transmembrane receptor protein kinase activity(GO:0019199)
0.0 0.4 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 3.8 GO:0051117 ATPase binding(GO:0051117)
0.0 0.2 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 2.1 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.9 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.2 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 1.6 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.3 GO:0070739 protein-glutamic acid ligase activity(GO:0070739)
0.0 0.6 GO:0005537 mannose binding(GO:0005537)
0.0 1.3 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.1 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.0 0.3 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.5 GO:0032183 SUMO binding(GO:0032183)
0.0 0.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.5 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.3 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 13.3 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 1.1 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 2.2 GO:0015645 fatty acid ligase activity(GO:0015645)
0.0 1.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.4 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 1.1 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 0.9 GO:0030507 spectrin binding(GO:0030507)
0.0 1.0 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.9 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.7 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.7 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.5 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.7 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 1.1 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.5 GO:0005496 steroid binding(GO:0005496)
0.0 1.0 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 1.1 GO:0005518 collagen binding(GO:0005518)
0.0 0.3 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.5 GO:0051018 protein kinase A binding(GO:0051018)
0.0 1.7 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0016616)
0.0 0.0 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0 0.2 GO:0043531 ADP binding(GO:0043531)
0.0 0.6 GO:0043022 ribosome binding(GO:0043022)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.6 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.2 9.7 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.2 3.1 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 3.6 PID_CONE_PATHWAY Visual signal transduction: Cones
0.1 0.6 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.1 3.4 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 5.7 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.1 0.7 PID_IFNG_PATHWAY IFN-gamma pathway
0.1 6.1 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 6.6 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 6.5 PID_PTP1B_PATHWAY Signaling events mediated by PTP1B
0.1 4.4 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 1.3 PID_PS1_PATHWAY Presenilin action in Notch and Wnt signaling
0.0 1.5 ST_GA12_PATHWAY G alpha 12 Pathway
0.0 1.3 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.7 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.0 PID_INTEGRIN_CS_PATHWAY Integrin family cell surface interactions
0.0 0.5 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.0 1.5 PID_SHP2_PATHWAY SHP2 signaling
0.0 0.5 PID_NECTIN_PATHWAY Nectin adhesion pathway
0.0 0.8 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 6.6 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.6 PID_WNT_CANONICAL_PATHWAY Canonical Wnt signaling pathway
0.0 0.3 PID_ALK2_PATHWAY ALK2 signaling events
0.0 1.8 PID_P73PATHWAY p73 transcription factor network
0.0 0.7 ST_G_ALPHA_I_PATHWAY G alpha i Pathway
0.0 1.8 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.5 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 0.6 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.3 PID_MET_PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.7 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.0 0.4 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.3 PID_ARF_3PATHWAY Arf1 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 18.7 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.6 8.1 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.4 8.3 REACTOME_PROLACTIN_RECEPTOR_SIGNALING Genes involved in Prolactin receptor signaling
0.3 5.8 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism
0.3 7.5 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.3 7.4 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2 3.3 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.2 3.6 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism
0.2 1.8 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.2 2.7 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.2 0.7 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA Genes involved in G beta:gamma signalling through PLC beta
0.2 5.7 REACTOME_FATTY_ACYL_COA_BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.2 1.6 REACTOME_TRANSPORT_OF_ORGANIC_ANIONS Genes involved in Transport of organic anions
0.2 2.5 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 3.2 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 3.6 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS Genes involved in Activation of BH3-only proteins
0.1 2.7 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 2.3 REACTOME_REGULATION_OF_WATER_BALANCE_BY_RENAL_AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.1 1.0 REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 0.8 REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1 1.7 REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.1 6.0 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.1 5.2 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 2.7 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.1 15.6 REACTOME_G_ALPHA_I_SIGNALLING_EVENTS Genes involved in G alpha (i) signalling events
0.1 1.8 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 1.8 REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION Genes involved in MHC class II antigen presentation
0.1 1.0 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 11.4 REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 1.8 REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 1.4 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.8 REACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 1.4 REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 2.6 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.0 1.1 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 1.2 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.6 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.7 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.7 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 0.6 REACTOME_SIGNALLING_TO_P38_VIA_RIT_AND_RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 1.5 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.6 REACTOME_PYRUVATE_METABOLISM Genes involved in Pyruvate metabolism
0.0 0.8 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.5 REACTOME_BASIGIN_INTERACTIONS Genes involved in Basigin interactions
0.0 0.6 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.7 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.7 REACTOME_INTERFERON_GAMMA_SIGNALING Genes involved in Interferon gamma signaling
0.0 1.5 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.8 REACTOME_MEIOSIS Genes involved in Meiosis
0.0 1.2 REACTOME_ASPARAGINE_N_LINKED_GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.0 1.3 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.4 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.5 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 0.2 REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.2 REACTOME_FGFR4_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR4 ligand binding and activation