Project

GSE58827: Dynamics of the Mouse Liver

Navigation
Downloads

Results for Relb

Z-value: 0.32

Motif logo

logo of

Transcription factors associated with Relb

Gene Symbol Gene ID Gene Info
Relb
ENSMUSG00000002983.10 avian reticuloendotheliosis viral (v-rel) oncogene related B

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Relbmm10_v2_chr7_-_19629355_196294510.115.3e-01Click!

Activity profile of Relb motif

Sorted Z-values of Relb motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_40089688 2.16 ENSMUST00000068094.6
ENSMUST00000080171.2
Cyp2c50
cytochrome P450, family 2, subfamily c, polypeptide 50
chr17_+_37193889 1.74 ENSMUST00000038844.6
Ubd
ubiquitin D
chr5_+_90891234 1.64 ENSMUST00000031327.8
Cxcl1
chemokine (C-X-C motif) ligand 1
chr1_-_171196229 0.97 ENSMUST00000111332.1
Pcp4l1
Purkinje cell protein 4-like 1
chr7_-_99626936 0.94 ENSMUST00000178124.1
Gm4980
predicted gene 4980
chrX_+_36112110 0.72 ENSMUST00000033418.7
Il13ra1
interleukin 13 receptor, alpha 1
chr6_-_124741374 0.65 ENSMUST00000004389.5
Grcc10
gene rich cluster, C10 gene
chr15_-_31367527 0.64 ENSMUST00000076942.4
ENSMUST00000123325.1
ENSMUST00000110410.2
Ankrd33b
ankyrin repeat domain 33B
chr9_-_97018823 0.64 ENSMUST00000055433.4
Spsb4
splA/ryanodine receptor domain and SOCS box containing 4
chr2_-_5714490 0.63 ENSMUST00000044009.7
Camk1d
calcium/calmodulin-dependent protein kinase ID
chr12_-_54862783 0.51 ENSMUST00000078124.7
Cfl2
cofilin 2, muscle
chr14_+_55560480 0.51 ENSMUST00000121622.1
ENSMUST00000143431.1
ENSMUST00000150481.1
Dcaf11
DDB1 and CUL4 associated factor 11
chr15_-_98677451 0.50 ENSMUST00000120997.1
ENSMUST00000109149.2
ENSMUST00000003451.4
Rnd1
Rho family GTPase 1
chrX_+_157698910 0.49 ENSMUST00000136141.1
Smpx
small muscle protein, X-linked
chr4_+_43631935 0.47 ENSMUST00000030191.8
Npr2
natriuretic peptide receptor 2
chr16_-_30267524 0.46 ENSMUST00000064856.7
Cpn2
carboxypeptidase N, polypeptide 2
chrX_+_141475385 0.46 ENSMUST00000112931.1
ENSMUST00000112930.1
Col4a5
collagen, type IV, alpha 5
chr4_-_117133953 0.41 ENSMUST00000076859.5
Plk3
polo-like kinase 3
chr1_+_152399824 0.40 ENSMUST00000044311.8
Colgalt2
collagen beta(1-O)galactosyltransferase 2
chr15_-_89170688 0.39 ENSMUST00000060808.9
Plxnb2
plexin B2
chr2_-_76982455 0.38 ENSMUST00000011934.5
ENSMUST00000099981.2
ENSMUST00000099980.3
ENSMUST00000111882.2
ENSMUST00000140091.1
Ttn
titin
chr1_+_74791516 0.36 ENSMUST00000006718.8
Wnt10a
wingless related MMTV integration site 10a
chr10_+_102512216 0.35 ENSMUST00000055355.4
Rassf9
Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
chr5_-_33657889 0.34 ENSMUST00000019439.7
Tmem129
transmembrane protein 129
chr1_+_193301953 0.32 ENSMUST00000016315.9
Lamb3
laminin, beta 3
chr1_-_135258449 0.32 ENSMUST00000003135.7
Elf3
E74-like factor 3
chr10_-_77902467 0.32 ENSMUST00000057608.4
Lrrc3
leucine rich repeat containing 3
chr12_-_55492587 0.30 ENSMUST00000021413.7
Nfkbia
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha
chr7_+_28766747 0.29 ENSMUST00000170068.1
ENSMUST00000072965.4
Sirt2
sirtuin 2
chr6_+_122513583 0.29 ENSMUST00000032210.7
ENSMUST00000148517.1
Mfap5
microfibrillar associated protein 5
chr11_+_90030295 0.27 ENSMUST00000092788.3
Tmem100
transmembrane protein 100
chr17_+_35424842 0.26 ENSMUST00000174699.1
H2-Q6
histocompatibility 2, Q region locus 6
chr15_-_33405976 0.26 ENSMUST00000079057.6
1700084J12Rik
RIKEN cDNA 1700084J12 gene
chr2_+_10153563 0.26 ENSMUST00000026886.7
Itih5
inter-alpha (globulin) inhibitor H5
chrX_+_157699113 0.26 ENSMUST00000112521.1
Smpx
small muscle protein, X-linked
chr17_+_35424870 0.25 ENSMUST00000113879.3
H2-Q6
histocompatibility 2, Q region locus 6
chr2_+_59612034 0.25 ENSMUST00000112568.1
ENSMUST00000037526.4
Tanc1
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
chr2_-_5063932 0.24 ENSMUST00000027986.4
Optn
optineurin
chr2_+_18672384 0.24 ENSMUST00000171845.1
ENSMUST00000061158.4
Commd3
COMM domain containing 3
chr10_+_96616998 0.24 ENSMUST00000038377.7
Btg1
B cell translocation gene 1, anti-proliferative
chr2_-_34958129 0.24 ENSMUST00000172159.1
Traf1
TNF receptor-associated factor 1
chr7_-_19629355 0.24 ENSMUST00000049912.8
ENSMUST00000094762.3
ENSMUST00000098754.4
Relb
avian reticuloendotheliosis viral (v-rel) oncogene related B
chrX_+_103321398 0.23 ENSMUST00000033689.2
Cdx4
caudal type homeobox 4
chr8_+_72319033 0.23 ENSMUST00000067912.7
Klf2
Kruppel-like factor 2 (lung)
chr16_-_55838827 0.22 ENSMUST00000096026.2
ENSMUST00000036273.6
ENSMUST00000114457.1
Nfkbiz
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta
chr4_-_148500449 0.22 ENSMUST00000030840.3
Angptl7
angiopoietin-like 7
chr12_+_111166413 0.20 ENSMUST00000021706.4
Traf3
TNF receptor-associated factor 3
chr2_-_5063996 0.20 ENSMUST00000114996.1
Optn
optineurin
chr18_+_37484955 0.20 ENSMUST00000053856.4
Pcdhb17
protocadherin beta 17
chr7_-_70360593 0.19 ENSMUST00000032768.7
Nr2f2
nuclear receptor subfamily 2, group F, member 2
chr17_-_57149633 0.18 ENSMUST00000019633.7
Cd70
CD70 antigen
chr1_-_130887408 0.17 ENSMUST00000121040.1
Il24
interleukin 24
chr7_-_28766469 0.17 ENSMUST00000085851.5
ENSMUST00000032815.4
Nfkbib
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta
chr14_+_120478443 0.15 ENSMUST00000062117.6
Rap2a
RAS related protein 2a
chr8_+_46739745 0.15 ENSMUST00000034041.7
Irf2
interferon regulatory factor 2
chr10_-_93310963 0.15 ENSMUST00000151153.1
Elk3
ELK3, member of ETS oncogene family
chr14_+_54932695 0.15 ENSMUST00000037863.5
Il25
interleukin 25
chr17_+_42315947 0.14 ENSMUST00000048691.4
Ptchd4
patched domain containing 4
chr11_-_23770953 0.13 ENSMUST00000102864.3
Rel
reticuloendotheliosis oncogene
chr14_+_62760496 0.13 ENSMUST00000181344.1
4931440J10Rik
RIKEN cDNA 4931440J10 gene
chr12_+_111166349 0.12 ENSMUST00000117269.1
Traf3
TNF receptor-associated factor 3
chr1_+_15287259 0.12 ENSMUST00000175681.1
Kcnb2
potassium voltage gated channel, Shab-related subfamily, member 2
chr4_-_91399984 0.11 ENSMUST00000102799.3
Elavl2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr4_+_126262325 0.11 ENSMUST00000030660.8
Trappc3
trafficking protein particle complex 3
chr12_+_102948843 0.10 ENSMUST00000101099.5
Unc79
unc-79 homolog (C. elegans)
chr2_+_119972699 0.10 ENSMUST00000066058.7
Mapkbp1
mitogen-activated protein kinase binding protein 1
chr2_-_160313616 0.10 ENSMUST00000109475.2
Gm826
predicted gene 826
chr10_-_93311073 0.10 ENSMUST00000008542.5
Elk3
ELK3, member of ETS oncogene family
chr8_-_46739453 0.10 ENSMUST00000181167.1
Gm16675
predicted gene, 16675
chr2_+_143546144 0.09 ENSMUST00000028905.9
Pcsk2
proprotein convertase subtilisin/kexin type 2
chr15_-_89429093 0.09 ENSMUST00000170460.1
Chkb
choline kinase beta
chr17_+_35649708 0.08 ENSMUST00000171166.2
Sfta2
surfactant associated 2
chr4_-_40239779 0.07 ENSMUST00000037907.6
Ddx58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr2_-_27027909 0.07 ENSMUST00000102890.4
ENSMUST00000153388.1
ENSMUST00000045702.5
Slc2a6
solute carrier family 2 (facilitated glucose transporter), member 6
chr16_+_88728828 0.04 ENSMUST00000060494.6
Krtap13-1
keratin associated protein 13-1
chr4_+_99656299 0.04 ENSMUST00000087285.3
Foxd3
forkhead box D3
chrX_+_163908982 0.04 ENSMUST00000069041.8
Ap1s2
adaptor-related protein complex 1, sigma 2 subunit
chr18_+_36559972 0.03 ENSMUST00000134146.1
Ankhd1
ankyrin repeat and KH domain containing 1
chr1_-_45890078 0.02 ENSMUST00000183590.1
Gm5269
predicted gene 5269
chr2_-_125506385 0.00 ENSMUST00000028633.6
Fbn1
fibrillin 1
chr5_-_5663263 0.00 ENSMUST00000148193.1
A330021E22Rik
RIKEN cDNA A330021E22 gene

Network of associatons between targets according to the STRING database.

First level regulatory network of Relb

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0070947 neutrophil mediated killing of fungus(GO:0070947)
0.2 2.2 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.2 0.7 GO:0035963 response to interleukin-13(GO:0035962) cellular response to interleukin-13(GO:0035963)
0.2 0.6 GO:0036343 psychomotor behavior(GO:0036343)
0.1 0.5 GO:0030043 actin filament fragmentation(GO:0030043)
0.1 1.7 GO:0070842 aggresome assembly(GO:0070842)
0.1 0.4 GO:0043056 forward locomotion(GO:0043056)
0.1 0.4 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 0.4 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.1 0.6 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.1 0.5 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.5 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168) negative regulation of oocyte maturation(GO:1900194)
0.0 0.4 GO:0090166 Golgi disassembly(GO:0090166) regulation of chaperone-mediated autophagy(GO:1904714)
0.0 0.2 GO:0060849 regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.0 0.2 GO:0071499 response to laminar fluid shear stress(GO:0034616) cellular response to laminar fluid shear stress(GO:0071499)
0.0 0.2 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.3 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.0 0.5 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.4 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.1 GO:0009624 response to nematode(GO:0009624)
0.0 0.2 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.5 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 0.1 GO:0030070 insulin processing(GO:0030070)
0.0 0.4 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.3 GO:0060056 mammary gland involution(GO:0060056)
0.0 0.3 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.1 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.2 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.5 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 0.3 GO:0097435 fibril organization(GO:0097435)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0005927 muscle tendon junction(GO:0005927)
0.1 0.3 GO:0005610 laminin-5 complex(GO:0005610)
0.1 0.5 GO:0098651 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.0 0.3 GO:0033010 paranodal junction(GO:0033010)
0.0 0.5 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.3 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 1.7 GO:0016235 aggresome(GO:0016235)
0.0 0.4 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 0.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.3 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.2 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.4 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.5 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.2 GO:0071614 linoleic acid epoxygenase activity(GO:0071614)
0.1 1.4 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.5 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 1.7 GO:0070628 proteasome binding(GO:0070628)
0.1 0.3 GO:0042903 histone deacetylase activity (H4-K16 specific)(GO:0034739) tubulin deacetylase activity(GO:0042903)
0.1 0.3 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.1 0.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.4 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.5 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.4 GO:0031433 telethonin binding(GO:0031433)
0.0 0.5 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.3 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.1 GO:0004103 choline kinase activity(GO:0004103)
0.0 0.6 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.4 GO:0035250 UDP-galactosyltransferase activity(GO:0035250)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 2.1 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.5 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 1.4 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.3 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.2 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon