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GSE58827: Dynamics of the Mouse Liver

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Results for Rfx3_Rfx1_Rfx4

Z-value: 1.11

Motif logo

Transcription factors associated with Rfx3_Rfx1_Rfx4

Gene Symbol Gene ID Gene Info
ENSMUSG00000040929.10 regulatory factor X, 3 (influences HLA class II expression)
ENSMUSG00000031706.6 regulatory factor X, 1 (influences HLA class II expression)
ENSMUSG00000020037.9 regulatory factor X, 4 (influences HLA class II expression)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Rfx4mm10_v2_chr10_+_84756055_84756084-0.447.1e-03Click!
Rfx1mm10_v2_chr8_+_84066824_840668820.372.8e-02Click!
Rfx3mm10_v2_chr19_-_28010995_280110540.076.7e-01Click!

Activity profile of Rfx3_Rfx1_Rfx4 motif

Sorted Z-values of Rfx3_Rfx1_Rfx4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_23684019 2.51 ENSMUST00000085989.5
claudin 9
chr16_-_3908596 2.35 ENSMUST00000123235.2
RIKEN cDNA 1700037C18 gene
chr16_+_17646564 1.74 ENSMUST00000182117.1
ENSMUST00000182671.1
ENSMUST00000182344.1
coiled-coil domain containing 74A
chr2_-_164745916 1.74 ENSMUST00000109328.1
ENSMUST00000043448.1
WAP four-disulfide core domain 3
WAP four-disulfide core domain 3
chr12_-_84148449 1.69 ENSMUST00000061425.2
paraneoplastic antigen MA1
chr12_+_113185877 1.62 ENSMUST00000058491.6
transmembrane protein 121
chr9_+_8544196 1.60 ENSMUST00000050433.6
transient receptor potential cation channel, subfamily C, member 6
chr16_+_17646464 1.59 ENSMUST00000056962.4
coiled-coil domain containing 74A
chr18_+_60925612 1.53 ENSMUST00000102888.3
ENSMUST00000025519.4
calcium/calmodulin-dependent protein kinase II alpha
chr11_-_71033462 1.50 ENSMUST00000156068.2
RIKEN cDNA 6330403K07 gene
chr7_+_127091426 1.50 ENSMUST00000056288.5
expressed sequence AI467606
chr12_+_80518990 1.48 ENSMUST00000021558.6
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 16
chr9_+_62858085 1.45 ENSMUST00000034777.6
ENSMUST00000163820.1
calmodulin-like 4
chr1_-_90153396 1.44 ENSMUST00000113094.2
IQ motif containing with AAA domain
chr17_+_56304313 1.40 ENSMUST00000113035.1
ENSMUST00000113039.2
ENSMUST00000142387.1
ubiquitin-like, containing PHD and RING finger domains, 1
chr2_+_28700155 1.40 ENSMUST00000074156.6
adenylate kinase 8
chr7_-_6730412 1.39 ENSMUST00000051209.4
paternally expressed 3
chr5_+_33983534 1.38 ENSMUST00000114382.1
predicted gene 1673
chr6_+_29985317 1.35 ENSMUST00000124522.1
ENSMUST00000141679.1
RIKEN cDNA 1700023L04 gene
chr11_-_6606053 1.33 ENSMUST00000045713.3
NAC alpha domain containing
chr19_+_47178820 1.32 ENSMUST00000111808.3
neuralized homolog 1A (Drosophila)
chr5_+_33983437 1.27 ENSMUST00000114384.1
ENSMUST00000094869.5
ENSMUST00000114383.1
predicted gene 1673
chr10_-_79874233 1.26 ENSMUST00000166023.1
ENSMUST00000167707.1
ENSMUST00000165601.1
cDNA sequence BC005764
chr15_-_84557776 1.26 ENSMUST00000069476.4
leucine zipper, down-regulated in cancer 1-like
chr8_+_94984399 1.23 ENSMUST00000093271.6
G protein-coupled receptor 56
chr19_+_10001669 1.23 ENSMUST00000121418.1
RAB3A interacting protein (rabin3)-like 1
chr2_-_131160006 1.23 ENSMUST00000103188.3
ENSMUST00000133602.1
ENSMUST00000028800.5
RIKEN cDNA 1700037H04 gene
chr8_+_95055094 1.22 ENSMUST00000058479.6
coiled-coil domain containing 135
chr9_-_61946768 1.20 ENSMUST00000034815.7
kinesin family member 23
chr2_+_166792525 1.20 ENSMUST00000065753.1
transformation related protein 53 regulating kinase
chr5_-_114823460 1.13 ENSMUST00000140374.1
ENSMUST00000100850.4
predicted gene 20499
RIKEN cDNA 2610524H06 gene
chr2_+_121289589 1.13 ENSMUST00000094639.3
microtubule-associated protein 1 A
chr19_-_46327121 1.12 ENSMUST00000041391.4
ENSMUST00000096029.5
pleckstrin and Sec7 domain containing
chr17_+_24696234 1.12 ENSMUST00000019464.7
NADPH oxidase organizer 1
chr17_+_46254017 1.09 ENSMUST00000095262.4
leucine rich repeat containing 73
chr3_-_108536466 1.08 ENSMUST00000048012.6
ENSMUST00000106626.2
ENSMUST00000106625.3
RIKEN cDNA 5330417C22 gene
chr13_+_91461050 1.07 ENSMUST00000004094.8
ENSMUST00000042122.8
single-stranded DNA binding protein 2
chr7_+_99268338 1.07 ENSMUST00000107100.2
microtubule-associated protein 6
chr12_+_85746539 1.05 ENSMUST00000040461.3
major facilitator superfamily domain containing 7C
chr5_+_108369858 1.05 ENSMUST00000100944.2
predicted gene 10419
chr17_-_8101228 1.05 ENSMUST00000097422.4
predicted gene 1604A
chr10_+_80295930 1.04 ENSMUST00000105359.1
adenomatosis polyposis coli 2
chr17_-_31277327 1.03 ENSMUST00000024832.7
radial spoke head 1 homolog (Chlamydomonas)
chr10_+_42860348 1.03 ENSMUST00000063063.7
sex comb on midleg-like 4 (Drosophila)
chr13_+_55464237 1.03 ENSMUST00000046533.7
proline rich 7 (synaptic)
chr4_-_133967296 1.03 ENSMUST00000105893.1
high mobility group nucleosomal binding domain 2
chr14_-_56102458 0.99 ENSMUST00000015583.1
cathepsin G
chr16_+_44394771 0.98 ENSMUST00000099742.2
WD repeat domain 52
chr7_-_13054665 0.97 ENSMUST00000182515.1
ENSMUST00000069289.8
myeloid zinc finger 1
chrX_+_7919816 0.96 ENSMUST00000041096.3
proprotein convertase subtilisin/kexin type 1 inhibitor
chr4_-_133967235 0.95 ENSMUST00000123234.1
high mobility group nucleosomal binding domain 2
chr7_+_80186835 0.95 ENSMUST00000107383.1
ENSMUST00000032754.7
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr4_-_118620763 0.94 ENSMUST00000071972.4
WD repeat domain 65
chr8_-_4259257 0.93 ENSMUST00000053252.7
cortexin 1
chr14_+_60378242 0.92 ENSMUST00000022561.6
APC membrane recruitment 2
chr4_+_137681663 0.92 ENSMUST00000047243.5
Rap1 GTPase-activating protein
chr11_+_102248842 0.91 ENSMUST00000100392.4
cDNA sequence BC030867
chr8_+_119575235 0.90 ENSMUST00000093100.2
dynein, axonemal assembly factor 1
chr2_-_73775341 0.90 ENSMUST00000112024.3
ENSMUST00000166199.1
ENSMUST00000180045.1
chimerin (chimaerin) 1
chr15_-_79062866 0.89 ENSMUST00000151889.1
ENSMUST00000040676.4
ankyrin repeat domain 54
chr2_+_110017806 0.87 ENSMUST00000028580.5
coiled-coil domain containing 34
chr9_+_20652107 0.86 ENSMUST00000034689.6
protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1
chr5_-_114813943 0.86 ENSMUST00000061251.5
ENSMUST00000112160.3
RIKEN cDNA 1500011B03 gene
chr11_-_12026732 0.86 ENSMUST00000143915.1
growth factor receptor bound protein 10
chr5_+_30711564 0.85 ENSMUST00000114729.1
dihydropyrimidinase-like 5
chr11_+_61505138 0.83 ENSMUST00000102657.3
B9 protein domain 1
chr2_-_30048827 0.82 ENSMUST00000113711.2
WD repeat domain 34
chr7_-_4546567 0.82 ENSMUST00000065957.5
synaptotagmin V
chr19_-_4283033 0.81 ENSMUST00000167215.1
ENSMUST00000056888.6
ankyrin repeat domain 13 family, member D
chr9_-_121277160 0.80 ENSMUST00000051479.6
ENSMUST00000171923.1
unc-51-like kinase 4
chr11_-_116077927 0.80 ENSMUST00000156545.1
unc-13 homolog D (C. elegans)
chr1_+_20951666 0.80 ENSMUST00000038447.4
EF-hand domain (C-terminal) containing 1
chr13_-_100775844 0.79 ENSMUST00000075550.3
centromere protein H
chr17_+_34604262 0.79 ENSMUST00000174041.1
1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)
chr5_+_137758133 0.79 ENSMUST00000141733.1
ENSMUST00000110985.1
TSC22 domain family, member 4
chr2_+_181219998 0.78 ENSMUST00000050026.6
ENSMUST00000108835.1
cDNA sequence BC051628
chr9_-_60687459 0.77 ENSMUST00000114032.1
ENSMUST00000166168.1
ENSMUST00000132366.1
leucine rich repeat containing 49
chr1_-_60043087 0.76 ENSMUST00000027172.6
islet cell autoantigen 1-like
chr8_-_84197667 0.76 ENSMUST00000181282.1
predicted gene, 26887
chr10_+_42860648 0.75 ENSMUST00000105495.1
sex comb on midleg-like 4 (Drosophila)
chr12_-_110840905 0.75 ENSMUST00000177224.1
ENSMUST00000084974.4
ENSMUST00000070565.8
serine/threonine kinase 30
chr4_-_127330799 0.73 ENSMUST00000046532.3
gap junction protein, beta 3
chr3_-_89245159 0.73 ENSMUST00000090924.6
tripartite motif-containing 46
chr17_+_35049966 0.73 ENSMUST00000007257.9
chloride intracellular channel 1
chr1_+_172521044 0.72 ENSMUST00000085894.5
ENSMUST00000161140.1
ENSMUST00000162988.1
coiled-coil domain containing 19
chr5_-_138172383 0.72 ENSMUST00000000505.9
minichromosome maintenance deficient 7 (S. cerevisiae)
chr11_-_116077954 0.71 ENSMUST00000106451.1
ENSMUST00000075036.2
unc-13 homolog D (C. elegans)
chr13_+_21945084 0.70 ENSMUST00000176511.1
ENSMUST00000102978.1
ENSMUST00000152258.2
zinc finger protein 184 (Kruppel-like)
chr1_+_171767123 0.70 ENSMUST00000015460.4
signaling lymphocytic activation molecule family member 1
chr11_+_106374820 0.70 ENSMUST00000106816.1
RIKEN cDNA 2310007L24 gene
chr2_-_131174653 0.69 ENSMUST00000127987.1
sperm flagellar 1
chr3_+_67374116 0.69 ENSMUST00000061322.8
myeloid leukemia factor 1
chr6_-_102464667 0.68 ENSMUST00000032159.6
contactin 3
chr9_-_27155418 0.68 ENSMUST00000167074.1
ENSMUST00000034472.8
junction adhesion molecule 3
chr3_+_124321031 0.68 ENSMUST00000058994.4
translocation associated membrane protein 1-like 1
chr3_+_67374091 0.67 ENSMUST00000077916.5
myeloid leukemia factor 1
chr5_+_124598749 0.67 ENSMUST00000130912.1
ENSMUST00000100706.3
tectonic family member 2
chr5_-_136170634 0.67 ENSMUST00000041048.1
ORAI calcium release-activated calcium modulator 2
chr7_-_13054514 0.67 ENSMUST00000182087.1
myeloid zinc finger 1
chr11_-_87359011 0.67 ENSMUST00000055438.4
protein phosphatase 1E (PP2C domain containing)
chr5_+_77016023 0.67 ENSMUST00000031161.4
ENSMUST00000117880.1
RIKEN cDNA 1700023E05 gene
chr7_+_118855735 0.66 ENSMUST00000098087.2
ENSMUST00000106547.1
IQ motif containing K
chr2_+_110017879 0.66 ENSMUST00000150183.2
coiled-coil domain containing 34
chr5_-_140702241 0.65 ENSMUST00000077890.5
ENSMUST00000041783.7
ENSMUST00000142081.1
IQ motif containing E
chr17_+_12119274 0.65 ENSMUST00000024594.2
1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta)
chr1_-_156674290 0.64 ENSMUST00000079625.4
torsin family 3, member A
chr14_-_49245389 0.64 ENSMUST00000130853.1
ENSMUST00000022398.7
RIKEN cDNA 1700011H14 gene
chrX_+_73123068 0.63 ENSMUST00000179117.1
predicted gene 14685
chr11_+_87760533 0.63 ENSMUST00000039627.5
ENSMUST00000100644.3
benzodiazepine receptor associated protein 1
chr17_-_46247968 0.62 ENSMUST00000142706.2
ENSMUST00000173349.1
ENSMUST00000087026.6
polymerase (RNA) I polypeptide C
chr11_-_116077562 0.61 ENSMUST00000174822.1
unc-13 homolog D (C. elegans)
chr3_-_55055038 0.61 ENSMUST00000029368.2
cyclin A1
chr18_-_77047243 0.61 ENSMUST00000137354.1
ENSMUST00000137498.1
katanin p60 subunit A-like 2
chr6_-_122339627 0.61 ENSMUST00000161210.1
ENSMUST00000161054.1
ENSMUST00000159252.1
ENSMUST00000161739.1
ENSMUST00000161149.1
polyhomeotic-like 1 (Drosophila)
chr11_+_49794157 0.60 ENSMUST00000020629.4
glutamine fructose-6-phosphate transaminase 2
chr11_-_67965631 0.60 ENSMUST00000021287.5
ENSMUST00000126766.1
WD repeat domain 16
chr11_+_43474276 0.60 ENSMUST00000173002.1
ENSMUST00000057679.3
C1q and tumor necrosis factor related protein 2
chr4_+_126058557 0.60 ENSMUST00000035497.4
organic solute carrier partner 1
chr17_-_31855782 0.59 ENSMUST00000024839.4
salt inducible kinase 1
chr9_+_107547288 0.59 ENSMUST00000010188.7
zinc finger, MYND domain containing 10
chr8_+_69832633 0.58 ENSMUST00000131637.2
ENSMUST00000081503.6
pre B cell leukemia homeobox 4
chr5_-_115300912 0.58 ENSMUST00000112090.1
dynein light chain LC8-type 1
chr8_-_84104773 0.58 ENSMUST00000041367.7
DDB1 and CUL4 associated factor 15
chr7_+_126950837 0.58 ENSMUST00000106332.1
seizure related 6 homolog like 2
chr8_-_22125030 0.58 ENSMUST00000169834.1
NIMA (never in mitosis gene a)-related expressed kinase 5
chr7_-_127588595 0.57 ENSMUST00000072155.3
predicted gene 166
chr11_+_69070790 0.57 ENSMUST00000075980.5
ENSMUST00000094081.4
transmembrane protein 107
chr7_-_140082246 0.57 ENSMUST00000166758.2
calcyon neuron-specific vesicular protein
chr17_+_84626458 0.57 ENSMUST00000025101.8
dynein cytoplasmic 2 light intermediate chain 1
chr6_-_146954399 0.57 ENSMUST00000111622.1
ENSMUST00000036592.8
RIKEN cDNA 1700034J05 gene
chr5_-_115300957 0.56 ENSMUST00000009157.3
dynein light chain LC8-type 1
chr15_+_54745702 0.56 ENSMUST00000050027.8
nephroblastoma overexpressed gene
chr7_+_4740111 0.56 ENSMUST00000098853.2
suppressor of variegation 4-20 homolog 2 (Drosophila)
chr7_+_4740178 0.56 ENSMUST00000108583.2
suppressor of variegation 4-20 homolog 2 (Drosophila)
chr11_+_75999912 0.56 ENSMUST00000066408.5
RIKEN cDNA 1700016K19 gene
chr9_-_98563580 0.56 ENSMUST00000058992.2
RIKEN cDNA 4930579K19 gene
chrX_+_136993147 0.56 ENSMUST00000113067.1
ENSMUST00000101227.2
zinc finger, CCHC domain containing 18
chr7_+_16816299 0.55 ENSMUST00000108495.2
striatin, calmodulin binding protein 4
chr11_-_3895085 0.55 ENSMUST00000020712.4
RIKEN cDNA 4921536K21 gene
chr9_-_8042785 0.55 ENSMUST00000065291.1
RIKEN cDNA 9230110C19 gene
chr5_-_115652974 0.55 ENSMUST00000121746.1
ENSMUST00000118576.1
coiled-coil domain containing 64
chr8_-_111933761 0.55 ENSMUST00000034429.7
transmembrane protein 231
chr7_-_31051431 0.54 ENSMUST00000073892.4
FXYD domain-containing ion transport regulator 7
chr15_-_68258787 0.54 ENSMUST00000162173.1
ENSMUST00000160248.1
ENSMUST00000159430.1
ENSMUST00000162054.1
zinc finger and AT hook domain containing
chr14_+_77156733 0.54 ENSMUST00000022589.7
ecto-NOX disulfide-thiol exchanger 1
chr10_+_122678764 0.54 ENSMUST00000161487.1
ENSMUST00000067918.5
protein phosphatase 1H (PP2C domain containing)
chr4_+_111720187 0.54 ENSMUST00000084354.3
spermatogenesis associated 6
chr7_+_126950518 0.54 ENSMUST00000106335.1
ENSMUST00000146017.1
seizure related 6 homolog like 2
chr16_-_16829276 0.54 ENSMUST00000023468.5
sperm associated antigen 6
chr17_-_80207299 0.53 ENSMUST00000063417.9
serine/arginine-rich splicing factor 7
chr8_-_92355764 0.53 ENSMUST00000180102.1
ENSMUST00000179421.1
ENSMUST00000179222.1
ENSMUST00000179029.1
RIKEN cDNA 4933436C20 gene
chr3_-_89245005 0.53 ENSMUST00000107464.1
tripartite motif-containing 46
chr15_+_79141324 0.52 ENSMUST00000040077.6
polymerase (RNA) II (DNA directed) polypeptide F
chr7_-_44748306 0.52 ENSMUST00000118162.1
ENSMUST00000140599.2
ENSMUST00000120798.1
zinc finger protein 473
chr4_+_111719975 0.52 ENSMUST00000038868.7
ENSMUST00000070513.6
ENSMUST00000153746.1
spermatogenesis associated 6
chr15_+_75704280 0.52 ENSMUST00000121137.1
ENSMUST00000023244.5
rhophilin, Rho GTPase binding protein 1
chr9_-_60688118 0.52 ENSMUST00000114034.2
ENSMUST00000065603.5
leucine rich repeat containing 49
chr1_-_152766281 0.52 ENSMUST00000111859.1
ENSMUST00000148865.1
ral guanine nucleotide dissociation stimulator,-like 1
chr4_-_128962420 0.52 ENSMUST00000119354.1
ENSMUST00000106068.1
ENSMUST00000030581.3
arginine decarboxylase
chr10_-_68541842 0.52 ENSMUST00000020103.2
RIKEN cDNA 1700040L02 gene
chr4_-_138725262 0.52 ENSMUST00000105811.2
UBX domain protein 10
chr8_-_119575143 0.52 ENSMUST00000036049.4
hydroxysteroid dehydrogenase like 1
chr14_-_60197173 0.52 ENSMUST00000131670.1
ATPase, aminophospholipid transporter-like, class I, type 8A, member 2
chr3_-_101287897 0.51 ENSMUST00000029456.4
CD2 antigen
chr17_-_6655939 0.51 ENSMUST00000179554.1
dynein light chain Tctex-type 1F
chr6_+_128375456 0.51 ENSMUST00000100926.2
RIKEN cDNA 4933413G19 gene
chr18_+_31609512 0.51 ENSMUST00000164667.1
RIKEN cDNA B930094E09 gene
chr5_+_30711849 0.51 ENSMUST00000088081.4
ENSMUST00000101442.3
dihydropyrimidinase-like 5
chr7_+_126950687 0.51 ENSMUST00000106333.1
seizure related 6 homolog like 2
chr4_+_107830958 0.50 ENSMUST00000106731.2
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
chrX_+_74837196 0.50 ENSMUST00000114116.1
predicted gene 5936
chr12_+_52699297 0.50 ENSMUST00000095737.3
A kinase (PRKA) anchor protein 6
chr11_-_101551837 0.50 ENSMUST00000017290.4
breast cancer 1
chr11_-_114795888 0.49 ENSMUST00000000206.3
BTB (POZ) domain containing 17
chr4_-_154042660 0.49 ENSMUST00000047207.6
coiled-coil domain containing 27
chr6_+_119175247 0.49 ENSMUST00000112777.2
ENSMUST00000073909.5
DCP1 decapping enzyme homolog B (S. cerevisiae)
chr17_+_6430112 0.49 ENSMUST00000179569.1
dynein light chain Tctex-type 1B
chr11_-_118342500 0.49 ENSMUST00000103024.3
cDNA sequence BC100451
chr10_+_20952547 0.49 ENSMUST00000105525.4
Abelson helper integration site 1
chr2_+_153492790 0.49 ENSMUST00000109783.1
RIKEN cDNA 4930404H24 gene
chr7_+_4740137 0.48 ENSMUST00000130215.1
ENSMUST00000108582.3
suppressor of variegation 4-20 homolog 2 (Drosophila)
chr10_+_119992962 0.48 ENSMUST00000154238.1
glutamate receptor interacting protein 1
chr10_-_39133914 0.48 ENSMUST00000135785.1
family with sequence similarity 229, member B
chr19_-_7241216 0.48 ENSMUST00000025675.9
N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog (S. cerevisiae)
chr16_+_20696175 0.48 ENSMUST00000128273.1
family with sequence similarity 131, member A
chr7_+_139212974 0.48 ENSMUST00000016124.8
leucine rich repeat containing 27
chr2_-_21205342 0.48 ENSMUST00000027992.2
enkurin, TRPC channel interacting protein
chr10_+_119992916 0.48 ENSMUST00000105261.2
glutamate receptor interacting protein 1
chr3_-_101287879 0.48 ENSMUST00000152321.1
CD2 antigen
chr11_-_119300070 0.48 ENSMUST00000026667.8
eukaryotic translation initiation factor 4A3
chr7_+_19149722 0.47 ENSMUST00000049294.2
small nuclear ribonucleoprotein D2
chr19_-_10457447 0.47 ENSMUST00000171400.2
leucine rich repeat containing 10B
chr15_-_79141197 0.47 ENSMUST00000169604.1
RIKEN cDNA 1700088E04 gene
chr4_-_152477433 0.47 ENSMUST00000159186.1
ENSMUST00000162017.1
ENSMUST00000030768.2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chrX_-_136993027 0.47 ENSMUST00000171738.1
ENSMUST00000056674.5
ENSMUST00000129807.1
solute carrier family 25, member 53
chr5_+_103425181 0.47 ENSMUST00000048957.9
protein tyrosine phosphatase, non-receptor type 13
chr17_+_6007580 0.47 ENSMUST00000115784.1
ENSMUST00000115785.1
synaptojanin 2
chr17_-_34836869 0.47 ENSMUST00000077477.5
serine/threonine kinase 19
chr12_-_69790660 0.47 ENSMUST00000021377.4
cyclin-dependent kinase-like 1 (CDC2-related kinase)
chr5_+_111581422 0.46 ENSMUST00000064930.3
RIKEN cDNA C130026L21 gene

Network of associatons between targets according to the STRING database.

First level regulatory network of Rfx3_Rfx1_Rfx4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 0.7 GO:2000349 negative regulation of CD40 signaling pathway(GO:2000349)
0.4 1.2 GO:0000912 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.3 1.4 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.3 0.8 GO:1904569 regulation of selenocysteine incorporation(GO:1904569)
0.2 5.8 GO:0044458 motile cilium assembly(GO:0044458)
0.2 2.1 GO:0002432 granuloma formation(GO:0002432)
0.2 0.9 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.2 0.7 GO:0045763 regulation of arginine metabolic process(GO:0000821) negative regulation of nitric oxide mediated signal transduction(GO:0010751) negative regulation of cellular amino acid metabolic process(GO:0045763)
0.2 0.6 GO:1904057 negative regulation of SMAD protein import into nucleus(GO:0060392) endothelial cell-cell adhesion(GO:0071603) negative regulation of sensory perception of pain(GO:1904057) bone regeneration(GO:1990523)
0.2 0.6 GO:0016598 protein arginylation(GO:0016598)
0.2 0.7 GO:1903575 cornified envelope assembly(GO:1903575)
0.2 0.5 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.2 0.5 GO:0030862 positive regulation of polarized epithelial cell differentiation(GO:0030862)
0.2 0.2 GO:0030860 regulation of polarized epithelial cell differentiation(GO:0030860)
0.1 1.6 GO:0098953 receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
0.1 0.4 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.1 0.6 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.1 0.5 GO:2000481 positive regulation of cAMP-dependent protein kinase activity(GO:2000481)
0.1 0.4 GO:0071918 urea transmembrane transport(GO:0071918)
0.1 1.1 GO:0036309 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.1 0.4 GO:0045013 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.1 0.5 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.1 1.0 GO:0070944 neutrophil mediated killing of bacterium(GO:0070944)
0.1 0.4 GO:1903898 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202) negative regulation of PERK-mediated unfolded protein response(GO:1903898)
0.1 1.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 1.0 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.1 0.6 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.1 0.1 GO:0003356 regulation of cilium beat frequency(GO:0003356)
0.1 1.4 GO:0007288 sperm axoneme assembly(GO:0007288)
0.1 1.4 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.1 0.4 GO:0046340 diacylglycerol catabolic process(GO:0046340) retrograde trans-synaptic signaling(GO:0098917)
0.1 1.9 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.1 0.4 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.1 0.4 GO:0035470 positive regulation of vascular wound healing(GO:0035470)
0.1 0.3 GO:0070649 formin-nucleated actin cable assembly(GO:0070649)
0.1 0.3 GO:0090187 positive regulation of pancreatic juice secretion(GO:0090187)
0.1 0.4 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.1 0.2 GO:0031660 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662)
0.1 0.3 GO:0008594 photoreceptor cell morphogenesis(GO:0008594)
0.1 0.8 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 0.9 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719)
0.1 1.0 GO:2000484 positive regulation of interleukin-8 secretion(GO:2000484)
0.1 0.3 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.1 1.6 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.1 0.7 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 0.3 GO:2001168 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.1 0.2 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.1 0.2 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.1 0.3 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.1 0.8 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.1 0.7 GO:0002441 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.1 0.5 GO:0061091 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.1 1.1 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.1 0.3 GO:0046210 nitrate catabolic process(GO:0043602) nitric oxide catabolic process(GO:0046210) cellular organohalogen metabolic process(GO:0090345) cellular organofluorine metabolic process(GO:0090346)
0.1 1.4 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.1 2.0 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.1 0.5 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 0.8 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.1 0.2 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.1 0.3 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.1 0.3 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.1 0.5 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.1 0.2 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.1 1.0 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.1 0.2 GO:0048611 ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611)
0.1 0.2 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.1 0.6 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.1 0.8 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.2 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
0.1 0.2 GO:0002355 detection of tumor cell(GO:0002355)
0.0 0.4 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.2 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.0 0.8 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.4 GO:0039532 negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway(GO:0039532)
0.0 0.1 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0 0.1 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.0 0.1 GO:1902220 positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902220)
0.0 0.4 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.8 GO:0001539 cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285)
0.0 0.5 GO:0070995 NADPH oxidation(GO:0070995)
0.0 1.7 GO:0021591 ventricular system development(GO:0021591)
0.0 0.4 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.1 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.0 0.2 GO:0032439 endosome localization(GO:0032439) positive regulation of pinocytosis(GO:0048549)
0.0 0.2 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.0 0.1 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
0.0 0.1 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
0.0 0.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.4 GO:0043312 neutrophil degranulation(GO:0043312)
0.0 0.7 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 1.0 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.3 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.1 GO:0006532 aspartate biosynthetic process(GO:0006532)
0.0 0.2 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0 0.7 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.5 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.2 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.1 GO:0045415 negative regulation of interleukin-8 biosynthetic process(GO:0045415)
0.0 0.2 GO:0051365 leading edge cell differentiation(GO:0035026) cellular response to potassium ion starvation(GO:0051365)
0.0 0.1 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.1 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.0 0.1 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.0 0.1 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 0.2 GO:0048318 axial mesoderm development(GO:0048318)
0.0 0.2 GO:1903056 regulation of melanosome organization(GO:1903056)
0.0 0.4 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.1 GO:0009816 defense response, incompatible interaction(GO:0009814) defense response to bacterium, incompatible interaction(GO:0009816) regulation of defense response to bacterium, incompatible interaction(GO:1902477)
0.0 0.4 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.2 GO:0048102 autophagic cell death(GO:0048102)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.2 GO:0010288 response to lead ion(GO:0010288)
0.0 0.1 GO:0036451 cap mRNA methylation(GO:0036451)
0.0 0.2 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.0 0.8 GO:0051443 positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.0 0.9 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.4 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.9 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.0 0.1 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.8 GO:0022617 extracellular matrix disassembly(GO:0022617)
0.0 0.6 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 1.2 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.1 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.2 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.1 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.5 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.9 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.1 GO:0060018 astrocyte fate commitment(GO:0060018)
0.0 0.5 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.1 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.0 0.1 GO:1902237 positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902237)
0.0 0.1 GO:0072236 metanephric loop of Henle development(GO:0072236)
0.0 0.4 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.2 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.0 0.2 GO:0051013 microtubule severing(GO:0051013)
0.0 0.7 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.3 GO:0090178 regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.0 1.0 GO:0002437 inflammatory response to antigenic stimulus(GO:0002437)
0.0 1.0 GO:0032418 lysosome localization(GO:0032418)
0.0 0.1 GO:0042697 menopause(GO:0042697)
0.0 0.5 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.0 0.1 GO:0035247 peptidyl-arginine omega-N-methylation(GO:0035247)
0.0 0.1 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.0 0.1 GO:0071233 response to leucine(GO:0043201) cellular response to leucine(GO:0071233)
0.0 0.3 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.1 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.0 0.2 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.5 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.1 GO:0071500 cellular response to nitrosative stress(GO:0071500)
0.0 0.0 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 0.3 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.1 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.5 GO:0000132 establishment of mitotic spindle orientation(GO:0000132)
0.0 0.1 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.2 GO:0045060 negative thymic T cell selection(GO:0045060)
0.0 0.4 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.0 1.4 GO:0060563 neuroepithelial cell differentiation(GO:0060563)
0.0 0.4 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.3 GO:0008356 asymmetric cell division(GO:0008356)
0.0 0.5 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.1 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.3 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.0 GO:0072244 metanephric glomerular epithelium development(GO:0072244)
0.0 0.4 GO:0072520 seminiferous tubule development(GO:0072520)
0.0 0.7 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.1 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0 0.5 GO:0032469 endoplasmic reticulum calcium ion homeostasis(GO:0032469)
0.0 0.3 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.4 GO:0048665 neuron fate specification(GO:0048665)
0.0 0.0 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.0 0.1 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.0 0.3 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.1 GO:0006265 DNA topological change(GO:0006265)
0.0 0.0 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.0 0.1 GO:0046102 inosine metabolic process(GO:0046102)
0.0 0.0 GO:0006788 heme oxidation(GO:0006788)
0.0 0.2 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.3 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.3 GO:1903963 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.1 GO:1990769 proximal neuron projection(GO:1990769)
0.4 0.4 GO:1990716 axonemal central apparatus(GO:1990716)
0.4 1.5 GO:0099522 region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524)
0.2 1.2 GO:0097149 centralspindlin complex(GO:0097149)
0.2 3.5 GO:0036038 MKS complex(GO:0036038)
0.2 2.1 GO:0033093 Weibel-Palade body(GO:0033093)
0.2 0.5 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.1 0.7 GO:0033010 paranodal junction(GO:0033010)
0.1 1.1 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 1.1 GO:0072687 meiotic spindle(GO:0072687)
0.1 0.3 GO:0020016 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.1 0.5 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.1 1.6 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 1.3 GO:0016342 catenin complex(GO:0016342) lamellipodium membrane(GO:0031258)
0.1 1.4 GO:1904115 axon cytoplasm(GO:1904115)
0.1 0.5 GO:0070531 BRCA1-A complex(GO:0070531)
0.1 0.5 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 0.4 GO:0097443 sorting endosome(GO:0097443)
0.1 1.1 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 0.1 GO:0005687 U4 snRNP(GO:0005687)
0.1 0.2 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.1 1.9 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 0.4 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.3 GO:0033503 HULC complex(GO:0033503)
0.0 0.7 GO:0042555 MCM complex(GO:0042555)
0.0 0.9 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.4 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.2 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.6 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.4 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.5 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 0.6 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.5 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.2 GO:0005638 lamin filament(GO:0005638)
0.0 0.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 1.3 GO:0005921 gap junction(GO:0005921)
0.0 0.2 GO:1990745 EARP complex(GO:1990745)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 0.2 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.1 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.2 GO:0035976 AP1 complex(GO:0035976)
0.0 1.2 GO:0097440 apical dendrite(GO:0097440)
0.0 0.2 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.2 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.2 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 1.3 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.6 GO:0001741 XY body(GO:0001741)
0.0 0.1 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.3 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 1.3 GO:0000791 euchromatin(GO:0000791)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.1 GO:0034709 methylosome(GO:0034709)
0.0 0.1 GO:0098842 postsynaptic early endosome(GO:0098842)
0.0 1.1 GO:0031430 M band(GO:0031430)
0.0 4.4 GO:0031514 motile cilium(GO:0031514)
0.0 1.0 GO:0015030 Cajal body(GO:0015030)
0.0 0.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.1 GO:0032783 ELL-EAF complex(GO:0032783)
0.0 0.4 GO:0044292 dendrite terminus(GO:0044292)
0.0 0.4 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.4 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.3 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.2 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.1 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.0 0.2 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.9 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.2 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.3 GO:0071565 nBAF complex(GO:0071565)
0.0 0.3 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.5 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.5 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.9 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 1.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.6 GO:1990391 DNA repair complex(GO:1990391)
0.0 4.0 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.1 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.1 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.2 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.4 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 0.6 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.6 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.3 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0004127 cytidylate kinase activity(GO:0004127)
0.3 0.8 GO:0008158 hedgehog receptor activity(GO:0008158)
0.2 1.4 GO:0031493 nucleosomal histone binding(GO:0031493)
0.2 1.4 GO:0032027 myosin light chain binding(GO:0032027)
0.2 2.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.2 0.9 GO:0050816 phosphothreonine binding(GO:0050816)
0.2 0.8 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.2 0.8 GO:0043515 kinetochore binding(GO:0043515)
0.2 1.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 0.1 GO:0005119 smoothened binding(GO:0005119)
0.1 0.8 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 0.5 GO:0038025 reelin receptor activity(GO:0038025)
0.1 1.1 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 1.3 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 0.9 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.1 0.9 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 1.8 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.1 0.2 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.1 0.3 GO:0001729 ceramide kinase activity(GO:0001729)
0.1 0.2 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.1 0.4 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.1 0.2 GO:0031127 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.1 0.5 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 1.1 GO:0001054 RNA polymerase I activity(GO:0001054)
0.1 0.5 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.1 1.5 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.4 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.1 0.3 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.1 1.4 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 0.2 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.1 1.5 GO:0001618 virus receptor activity(GO:0001618)
0.1 0.3 GO:0008941 nitric oxide dioxygenase activity(GO:0008941) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor(GO:0016708) iron-cytochrome-c reductase activity(GO:0047726)
0.1 0.4 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.1 0.7 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.1 0.2 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.1 0.2 GO:0071633 dihydroceramidase activity(GO:0071633)
0.1 0.3 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.1 0.6 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.4 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.1 0.2 GO:0052594 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.1 0.5 GO:1990446 U1 snRNP binding(GO:1990446)
0.1 0.2 GO:0000700 mismatch base pair DNA N-glycosylase activity(GO:0000700)
0.0 0.4 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.2 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.0 0.4 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.0 0.3 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.3 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.0 0.5 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.6 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.3 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.0 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.0 0.3 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.3 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.5 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0 0.5 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.1 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.9 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.5 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.3 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0004802 transketolase activity(GO:0004802)
0.0 0.4 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.1 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.0 0.1 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.0 0.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 1.1 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 1.5 GO:0045182 translation regulator activity(GO:0045182)
0.0 0.3 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.1 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.0 0.2 GO:0035240 dopamine binding(GO:0035240)
0.0 0.6 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 1.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.2 GO:0034711 inhibin binding(GO:0034711)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.1 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.1 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.0 0.5 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.9 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.5 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.1 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0 0.7 GO:0071949 FAD binding(GO:0071949)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 2.0 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.5 GO:0008483 transaminase activity(GO:0008483)
0.0 0.2 GO:0015925 galactosidase activity(GO:0015925)
0.0 0.1 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.4 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.1 GO:0061513 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.4 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 1.0 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.1 GO:0030621 U4 snRNA binding(GO:0030621)
0.0 1.2 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.1 GO:0030943 mitochondrion targeting sequence binding(GO:0030943)
0.0 0.6 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.1 GO:0052723 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.0 0.2 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.7 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.1 GO:1904288 BAT3 complex binding(GO:1904288)
0.0 1.3 GO:0005518 collagen binding(GO:0005518)
0.0 0.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.1 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.4 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.3 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.2 GO:0070403 NAD+ binding(GO:0070403)
0.0 2.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.5 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.1 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 1.2 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.1 GO:0046403 polynucleotide 3'-phosphatase activity(GO:0046403)
0.0 0.3 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:1990599 oxidized DNA binding(GO:0032356) 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.1 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.1 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 1.1 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.2 GO:0048156 tau protein binding(GO:0048156)
0.0 0.2 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.9 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.7 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.1 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.6 GO:0016836 hydro-lyase activity(GO:0016836)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.8 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 2.1 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.9 PID MYC PATHWAY C-MYC pathway
0.0 1.0 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.8 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.9 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.7 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.5 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.1 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 1.3 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.5 PID AURORA A PATHWAY Aurora A signaling
0.0 1.2 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.2 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.9 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.4 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.7 PID AURORA B PATHWAY Aurora B signaling
0.0 0.6 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.7 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.6 PID ATR PATHWAY ATR signaling pathway
0.0 0.5 PID PLK1 PATHWAY PLK1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.6 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 0.4 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.1 1.4 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 1.5 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.1 1.6 REACTOME KINESINS Genes involved in Kinesins
0.1 1.5 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 2.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 1.6 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 0.7 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 1.0 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.7 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.9 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.6 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.5 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0 0.7 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.6 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.9 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 1.5 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.2 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.5 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.4 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.3 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.5 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.4 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.4 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.4 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.3 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.4 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.9 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.1 REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway
0.0 0.4 REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.0 0.3 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.8 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.7 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 1.3 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.3 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.2 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 1.3 REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION Genes involved in 3' -UTR-mediated translational regulation
0.0 0.4 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.4 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.2 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1