Motif ID: Runx2_Bcl11a

Z-value: 2.774

Transcription factors associated with Runx2_Bcl11a:

Gene SymbolEntrez IDGene Name
Bcl11a ENSMUSG00000000861.9 Bcl11a
Runx2 ENSMUSG00000039153.10 Runx2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Bcl11amm10_v2_chr11_+_24078022_240780760.821.3e-09Click!
Runx2mm10_v2_chr17_-_44735612_447357100.782.0e-08Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Runx2_Bcl11a

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_-_87875524 33.935 ENSMUST00000049768.3
Epx
eosinophil peroxidase
chr11_+_87793470 26.914 ENSMUST00000020779.4
Mpo
myeloperoxidase
chr11_+_87793722 25.341 ENSMUST00000143021.2
Mpo
myeloperoxidase
chr7_+_143005046 25.237 ENSMUST00000009396.6
Tspan32
tetraspanin 32
chr4_-_46404224 21.613 ENSMUST00000107764.2
Hemgn
hemogen
chr18_-_35649349 20.888 ENSMUST00000025211.4
Mzb1
marginal zone B and B1 cell-specific protein 1
chr5_+_90768511 20.686 ENSMUST00000031319.6
Ppbp
pro-platelet basic protein
chr7_+_143005677 19.860 ENSMUST00000082008.5
ENSMUST00000105925.1
ENSMUST00000105924.1
Tspan32


tetraspanin 32


chr7_+_143005638 19.770 ENSMUST00000075172.5
ENSMUST00000105923.1
Tspan32

tetraspanin 32

chr7_-_142661858 18.831 ENSMUST00000145896.2
Igf2
insulin-like growth factor 2
chr10_+_75564086 17.613 ENSMUST00000141062.1
ENSMUST00000152657.1
Ggt1

gamma-glutamyltransferase 1

chr16_-_92826004 17.158 ENSMUST00000023673.7
Runx1
runt related transcription factor 1
chr7_-_141016892 16.917 ENSMUST00000081924.3
Ifitm6
interferon induced transmembrane protein 6
chr14_-_56262233 16.721 ENSMUST00000015581.4
Gzmb
granzyme B
chr16_+_36277145 15.954 ENSMUST00000042097.9
Stfa1
stefin A1
chr2_-_28084877 14.816 ENSMUST00000028179.8
ENSMUST00000117486.1
ENSMUST00000135472.1
Fcnb


ficolin B


chr7_-_142666816 14.249 ENSMUST00000105935.1
Igf2
insulin-like growth factor 2
chr11_-_69617879 13.793 ENSMUST00000005334.2
Shbg
sex hormone binding globulin
chr17_+_33638056 13.129 ENSMUST00000052079.7
Pram1
PML-RAR alpha-regulated adaptor molecule 1
chr17_-_35085609 12.893 ENSMUST00000038507.6
Ly6g6f
lymphocyte antigen 6 complex, locus G6F
chr7_-_103827922 12.588 ENSMUST00000023934.6
ENSMUST00000153218.1
Hbb-bs

hemoglobin, beta adult s chain

chr8_-_11008458 11.923 ENSMUST00000040514.6
Irs2
insulin receptor substrate 2
chr4_+_115057410 11.818 ENSMUST00000136946.1
Tal1
T cell acute lymphocytic leukemia 1
chr4_+_136172367 11.782 ENSMUST00000061721.5
E2f2
E2F transcription factor 2
chr10_-_79788924 11.289 ENSMUST00000020573.6
Prss57
protease, serine 57
chr13_-_19824234 11.219 ENSMUST00000065335.2
Gpr141
G protein-coupled receptor 141
chr11_-_11970540 11.175 ENSMUST00000109653.1
Grb10
growth factor receptor bound protein 10
chr3_-_59101810 10.773 ENSMUST00000085040.4
Gpr171
G protein-coupled receptor 171
chr7_-_142576492 10.560 ENSMUST00000140716.1
H19
H19 fetal liver mRNA
chr16_+_17980565 10.185 ENSMUST00000075371.3
Vpreb2
pre-B lymphocyte gene 2
chr9_+_8544196 10.123 ENSMUST00000050433.6
Trpc6
transient receptor potential cation channel, subfamily C, member 6
chr3_+_103860265 9.952 ENSMUST00000029433.7
Ptpn22
protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
chr5_-_107726017 9.937 ENSMUST00000159263.2
Gfi1
growth factor independent 1
chrX_+_93654863 9.905 ENSMUST00000113933.2
Pcyt1b
phosphate cytidylyltransferase 1, choline, beta isoform
chrX_+_159697308 9.624 ENSMUST00000123433.1
Sh3kbp1
SH3-domain kinase binding protein 1
chr16_-_36367623 9.539 ENSMUST00000096089.2
BC100530
cDNA sequence BC100530
chr1_+_135133272 9.260 ENSMUST00000167080.1
Ptpn7
protein tyrosine phosphatase, non-receptor type 7
chr10_+_43579161 9.225 ENSMUST00000058714.8
Cd24a
CD24a antigen
chr13_-_37050237 9.195 ENSMUST00000164727.1
F13a1
coagulation factor XIII, A1 subunit
chrX_-_8090442 9.132 ENSMUST00000033505.6
Was
Wiskott-Aldrich syndrome homolog (human)
chr16_+_36156801 9.102 ENSMUST00000079184.4
Stfa2l1
stefin A2 like 1
chr8_-_111691002 8.925 ENSMUST00000034435.5
Ctrb1
chymotrypsinogen B1
chr10_-_62379852 8.887 ENSMUST00000143236.1
ENSMUST00000133429.1
ENSMUST00000132926.1
ENSMUST00000116238.2
Hk1



hexokinase 1



chr13_+_76579670 8.858 ENSMUST00000126960.1
ENSMUST00000109583.2
Mctp1

multiple C2 domains, transmembrane 1

chr6_+_123123423 8.825 ENSMUST00000032248.7
Clec4a2
C-type lectin domain family 4, member a2
chr6_+_123123313 8.727 ENSMUST00000041779.6
Clec4a2
C-type lectin domain family 4, member a2
chr7_-_43533171 8.638 ENSMUST00000004728.5
ENSMUST00000039861.5
Cd33

CD33 antigen

chr7_+_44572370 8.523 ENSMUST00000002274.8
Napsa
napsin A aspartic peptidase
chr7_-_25005895 8.501 ENSMUST00000102858.3
ENSMUST00000080882.6
Atp1a3

ATPase, Na+/K+ transporting, alpha 3 polypeptide

chr19_-_20390944 8.499 ENSMUST00000025561.7
Anxa1
annexin A1
chr7_-_100863373 8.346 ENSMUST00000142885.1
ENSMUST00000008462.3
Relt

RELT tumor necrosis factor receptor

chr4_-_137430517 8.090 ENSMUST00000102522.4
Cela3b
chymotrypsin-like elastase family, member 3B
chr1_+_40515362 8.031 ENSMUST00000027237.5
Il18rap
interleukin 18 receptor accessory protein
chr7_-_14254870 8.009 ENSMUST00000184731.1
ENSMUST00000076576.6
Sult2a6

sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 6

chr2_-_26021679 7.940 ENSMUST00000036509.7
Ubac1
ubiquitin associated domain containing 1
chr11_-_83649349 7.904 ENSMUST00000001008.5
Ccl3
chemokine (C-C motif) ligand 3
chr2_-_32387760 7.860 ENSMUST00000050785.8
Lcn2
lipocalin 2
chr4_+_135120640 7.845 ENSMUST00000056977.7
Runx3
runt related transcription factor 3
chr2_-_26021532 7.751 ENSMUST00000136750.1
Ubac1
ubiquitin associated domain containing 1
chr17_+_35821675 7.704 ENSMUST00000003635.6
Ier3
immediate early response 3
chr5_+_90772435 7.559 ENSMUST00000031320.6
Pf4
platelet factor 4
chrX_-_136068236 7.510 ENSMUST00000049130.7
Bex2
brain expressed X-linked 2
chr15_+_44457522 7.486 ENSMUST00000166957.1
ENSMUST00000038336.5
Pkhd1l1

polycystic kidney and hepatic disease 1-like 1

chr12_-_4874341 7.317 ENSMUST00000137337.1
ENSMUST00000045921.7
Mfsd2b

major facilitator superfamily domain containing 2B

chr7_+_24370255 7.101 ENSMUST00000171904.1
Kcnn4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr14_+_80000292 7.018 ENSMUST00000088735.3
Olfm4
olfactomedin 4
chr4_-_43499608 6.941 ENSMUST00000136005.1
ENSMUST00000054538.6
Arhgef39

Rho guanine nucleotide exchange factor (GEF) 39

chr11_-_79523760 6.872 ENSMUST00000179322.1
Evi2b
ecotropic viral integration site 2b
chr8_+_88294204 6.872 ENSMUST00000098521.2
Adcy7
adenylate cyclase 7
chr2_-_58160495 6.791 ENSMUST00000028175.6
Cytip
cytohesin 1 interacting protein
chr17_+_36869567 6.763 ENSMUST00000060524.9
Trim10
tripartite motif-containing 10
chr7_-_142656018 6.665 ENSMUST00000178921.1
Igf2
insulin-like growth factor 2
chr17_-_35066170 6.550 ENSMUST00000174190.1
ENSMUST00000097337.1
AU023871

expressed sequence AU023871

chr13_+_112288451 6.439 ENSMUST00000022275.6
ENSMUST00000056047.7
ENSMUST00000165593.1
Ankrd55


ankyrin repeat domain 55


chr4_+_115057683 6.436 ENSMUST00000161601.1
Tal1
T cell acute lymphocytic leukemia 1
chr10_+_75571522 6.383 ENSMUST00000143226.1
ENSMUST00000124259.1
Ggt1

gamma-glutamyltransferase 1

chr6_-_129917650 6.304 ENSMUST00000118060.1
Klra5
killer cell lectin-like receptor, subfamily A, member 5
chr11_-_72550255 6.273 ENSMUST00000021154.6
Spns3
spinster homolog 3
chr17_+_47596061 6.189 ENSMUST00000182539.1
Ccnd3
cyclin D3
chr2_-_172370506 6.166 ENSMUST00000109139.1
ENSMUST00000028997.7
ENSMUST00000109140.3
Aurka


aurora kinase A


chr3_-_15332285 6.088 ENSMUST00000108361.1
Gm9733
predicted gene 9733
chr6_-_40585783 6.082 ENSMUST00000177178.1
ENSMUST00000129948.2
ENSMUST00000101491.4
Clec5a


C-type lectin domain family 5, member a


chr6_-_87533219 6.039 ENSMUST00000113637.2
ENSMUST00000071024.6
Arhgap25

Rho GTPase activating protein 25

chr2_-_28699661 5.975 ENSMUST00000124840.1
1700026L06Rik
RIKEN cDNA 1700026L06 gene
chr15_-_79285502 5.973 ENSMUST00000165408.1
Baiap2l2
BAI1-associated protein 2-like 2
chr14_-_60086832 5.875 ENSMUST00000080368.5
Atp8a2
ATPase, aminophospholipid transporter-like, class I, type 8A, member 2
chr11_+_3330781 5.870 ENSMUST00000136536.1
ENSMUST00000093399.4
Pik3ip1

phosphoinositide-3-kinase interacting protein 1

chr15_-_66801577 5.846 ENSMUST00000168589.1
Sla
src-like adaptor
chr7_+_143005770 5.832 ENSMUST00000143512.1
Tspan32
tetraspanin 32
chr15_-_103252810 5.810 ENSMUST00000154510.1
Nfe2
nuclear factor, erythroid derived 2
chr2_-_28699636 5.744 ENSMUST00000102877.1
1700026L06Rik
RIKEN cDNA 1700026L06 gene
chr19_-_4615453 5.679 ENSMUST00000053597.2
Lrfn4
leucine rich repeat and fibronectin type III domain containing 4
chr3_+_146150174 5.629 ENSMUST00000098524.4
Mcoln2
mucolipin 2
chr14_-_56085214 5.624 ENSMUST00000015594.7
Mcpt8
mast cell protease 8
chr1_+_135132693 5.570 ENSMUST00000049449.4
Ptpn7
protein tyrosine phosphatase, non-receptor type 7
chr17_-_13404191 5.531 ENSMUST00000115650.1
Gm8597
predicted gene 8597
chr14_+_55853997 5.477 ENSMUST00000100529.3
Nynrin
NYN domain and retroviral integrase containing
chrX_-_57338598 5.477 ENSMUST00000033468.4
ENSMUST00000114736.1
Arhgef6

Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6

chr3_+_96181151 5.476 ENSMUST00000035371.8
Sv2a
synaptic vesicle glycoprotein 2 a
chr14_+_55765956 5.463 ENSMUST00000057569.3
Ltb4r1
leukotriene B4 receptor 1
chr15_-_103255433 5.457 ENSMUST00000075192.6
Nfe2
nuclear factor, erythroid derived 2
chr15_-_9529868 5.358 ENSMUST00000003981.4
Il7r
interleukin 7 receptor
chr15_-_78493607 5.333 ENSMUST00000163494.1
Il2rb
interleukin 2 receptor, beta chain
chr11_-_106314494 5.236 ENSMUST00000167143.1
Cd79b
CD79B antigen
chr1_-_38664947 5.185 ENSMUST00000039827.7
ENSMUST00000027250.7
Aff3

AF4/FMR2 family, member 3

chr2_+_172393900 5.169 ENSMUST00000109136.2
Cass4
Cas scaffolding protein family member 4
chr15_-_79285470 5.004 ENSMUST00000170955.1
Baiap2l2
BAI1-associated protein 2-like 2
chr1_+_170277376 5.000 ENSMUST00000179976.1
Sh2d1b1
SH2 domain protein 1B1
chr17_-_28560704 4.983 ENSMUST00000114785.1
ENSMUST00000025062.3
Clps

colipase, pancreatic

chr9_+_53405280 4.982 ENSMUST00000005262.1
4930550C14Rik
RIKEN cDNA 4930550C14 gene
chr6_+_86628174 4.951 ENSMUST00000043400.6
Asprv1
aspartic peptidase, retroviral-like 1
chr14_+_66297029 4.923 ENSMUST00000022623.6
ENSMUST00000121006.1
Trim35

tripartite motif-containing 35

chr14_+_27000362 4.784 ENSMUST00000035433.8
Hesx1
homeobox gene expressed in ES cells
chr5_+_122100951 4.748 ENSMUST00000014080.6
ENSMUST00000111750.1
ENSMUST00000139213.1
ENSMUST00000111751.1
ENSMUST00000155612.1
Myl2




myosin, light polypeptide 2, regulatory, cardiac, slow




chr4_-_92191749 4.705 ENSMUST00000123179.1
Gm12666
predicted gene 12666
chr11_+_31832660 4.695 ENSMUST00000132857.1
Gm12107
predicted gene 12107
chr14_+_56042123 4.670 ENSMUST00000015576.4
Mcpt2
mast cell protease 2
chr17_-_35027909 4.661 ENSMUST00000040151.2
Sapcd1
suppressor APC domain containing 1
chr4_+_127172866 4.658 ENSMUST00000106094.2
Dlgap3
discs, large (Drosophila) homolog-associated protein 3
chr16_-_16869255 4.655 ENSMUST00000075017.4
Vpreb1
pre-B lymphocyte gene 1
chr6_+_87778084 4.636 ENSMUST00000032133.3
Gp9
glycoprotein 9 (platelet)
chr7_+_30776394 4.621 ENSMUST00000041703.7
Dmkn
dermokine
chr13_-_22219820 4.549 ENSMUST00000057516.1
Vmn1r193
vomeronasal 1 receptor 193
chr1_-_144775419 4.497 ENSMUST00000027603.3
Rgs18
regulator of G-protein signaling 18
chr19_-_4615647 4.496 ENSMUST00000113822.2
Lrfn4
leucine rich repeat and fibronectin type III domain containing 4
chr12_-_8539545 4.454 ENSMUST00000095863.3
ENSMUST00000165657.1
Slc7a15

solute carrier family 7 (cationic amino acid transporter, y+ system), member 15

chr12_-_112860886 4.412 ENSMUST00000021729.7
Gpr132
G protein-coupled receptor 132
chr10_-_62507737 4.377 ENSMUST00000020271.6
Srgn
serglycin
chr4_-_134012381 4.362 ENSMUST00000176113.1
Lin28a
lin-28 homolog A (C. elegans)
chr7_+_43437073 4.317 ENSMUST00000070518.2
Nkg7
natural killer cell group 7 sequence
chr19_-_5273080 4.290 ENSMUST00000025786.7
Pacs1
phosphofurin acidic cluster sorting protein 1
chr18_-_62179948 4.265 ENSMUST00000053640.3
Adrb2
adrenergic receptor, beta 2
chr11_-_102088471 4.189 ENSMUST00000017458.4
Mpp2
membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
chr10_-_117792663 4.136 ENSMUST00000167943.1
ENSMUST00000064848.5
Nup107

nucleoporin 107

chr15_-_75567176 4.118 ENSMUST00000156032.1
ENSMUST00000127095.1
Ly6h

lymphocyte antigen 6 complex, locus H

chr5_-_122002340 4.114 ENSMUST00000134326.1
Cux2
cut-like homeobox 2
chr2_-_73485733 4.074 ENSMUST00000102680.1
Wipf1
WAS/WASL interacting protein family, member 1
chr5_+_105519388 4.070 ENSMUST00000067924.6
ENSMUST00000150981.1
Lrrc8c

leucine rich repeat containing 8 family, member C

chr7_-_141655319 4.033 ENSMUST00000062451.7
Muc6
mucin 6, gastric
chr13_-_63398167 4.006 ENSMUST00000160735.1
Fancc
Fanconi anemia, complementation group C
chr2_-_73486456 3.985 ENSMUST00000141264.1
Wipf1
WAS/WASL interacting protein family, member 1
chr1_-_164935522 3.959 ENSMUST00000027860.7
Xcl1
chemokine (C motif) ligand 1
chr17_+_12119274 3.920 ENSMUST00000024594.2
Agpat4
1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta)
chr15_+_9436028 3.917 ENSMUST00000042360.3
Capsl
calcyphosine-like
chr9_-_95845215 3.914 ENSMUST00000093800.2
Pls1
plastin 1 (I-isoform)
chr11_+_3330401 3.905 ENSMUST00000045153.4
Pik3ip1
phosphoinositide-3-kinase interacting protein 1
chr5_+_66676098 3.880 ENSMUST00000031131.9
Uchl1
ubiquitin carboxy-terminal hydrolase L1
chr6_-_40951826 3.875 ENSMUST00000073642.5
Gm4744
predicted gene 4744
chr1_-_89933290 3.866 ENSMUST00000036954.7
Gbx2
gastrulation brain homeobox 2
chr17_+_8849974 3.863 ENSMUST00000115720.1
Pde10a
phosphodiesterase 10A
chr7_+_101361997 3.860 ENSMUST00000133423.1
Arap1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr3_-_54915867 3.840 ENSMUST00000070342.3
Sertm1
serine rich and transmembrane domain containing 1
chr11_-_17008647 3.827 ENSMUST00000102881.3
Plek
pleckstrin
chr9_+_51213683 3.821 ENSMUST00000034554.7
Pou2af1
POU domain, class 2, associating factor 1
chr2_-_28563362 3.776 ENSMUST00000028161.5
Cel
carboxyl ester lipase
chr10_+_118441044 3.772 ENSMUST00000068592.3
Ifng
interferon gamma
chr5_+_37047464 3.772 ENSMUST00000137019.1
Jakmip1
janus kinase and microtubule interacting protein 1
chr9_+_111004811 3.742 ENSMUST00000080872.4
Gm10030
predicted gene 10030
chr11_-_109472611 3.638 ENSMUST00000168740.1
Slc16a6
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr7_+_28540863 3.628 ENSMUST00000119180.2
Sycn
syncollin
chr10_-_62508097 3.592 ENSMUST00000159020.1
Srgn
serglycin
chr8_-_107065632 3.565 ENSMUST00000034393.5
Tmed6
transmembrane emp24 protein transport domain containing 6
chr13_+_76579681 3.542 ENSMUST00000109589.2
Mctp1
multiple C2 domains, transmembrane 1
chr7_+_43351378 3.482 ENSMUST00000012798.7
ENSMUST00000122423.1
ENSMUST00000121494.1
Siglec5


sialic acid binding Ig-like lectin 5


chr5_-_117319242 3.482 ENSMUST00000100834.1
Gm10399
predicted gene 10399
chr18_+_62180119 3.469 ENSMUST00000067743.1
Gm9949
predicted gene 9949
chr8_+_60655540 3.444 ENSMUST00000034066.3
Mfap3l
microfibrillar-associated protein 3-like
chr19_-_4305955 3.441 ENSMUST00000025791.5
Adrbk1
adrenergic receptor kinase, beta 1
chr8_-_68121527 3.439 ENSMUST00000178529.1
Gm21807
predicted gene, 21807
chr12_+_116077720 3.430 ENSMUST00000011315.3
Vipr2
vasoactive intestinal peptide receptor 2
chr6_+_49036518 3.412 ENSMUST00000031840.7
Gpnmb
glycoprotein (transmembrane) nmb
chr2_-_170427828 3.399 ENSMUST00000013667.2
ENSMUST00000109152.2
ENSMUST00000068137.4
Bcas1


breast carcinoma amplified sequence 1


chr16_+_32756336 3.395 ENSMUST00000135753.1
Muc4
mucin 4
chr5_+_139406387 3.335 ENSMUST00000052176.8
C130050O18Rik
RIKEN cDNA C130050O18 gene
chr5_+_37050854 3.328 ENSMUST00000043794.4
Jakmip1
janus kinase and microtubule interacting protein 1
chr17_-_48146306 3.313 ENSMUST00000063481.7
9830107B12Rik
RIKEN cDNA 9830107B12 gene
chr17_+_29093763 3.294 ENSMUST00000023829.6
Cdkn1a
cyclin-dependent kinase inhibitor 1A (P21)
chr15_-_36555556 3.241 ENSMUST00000161202.1
ENSMUST00000013755.5
Snx31

sorting nexin 31

chr5_+_86071734 3.226 ENSMUST00000031171.7
Stap1
signal transducing adaptor family member 1
chr11_-_100207507 3.214 ENSMUST00000007272.7
Krt14
keratin 14
chr7_-_3825641 3.196 ENSMUST00000094911.4
ENSMUST00000108619.1
ENSMUST00000108620.1
Gm15448


predicted gene 15448


chr7_+_127211608 3.193 ENSMUST00000032910.6
Mylpf
myosin light chain, phosphorylatable, fast skeletal muscle
chr13_+_113317084 3.159 ENSMUST00000136755.2
BC067074
cDNA sequence BC067074
chr16_-_58718724 3.152 ENSMUST00000089318.3
Gpr15
G protein-coupled receptor 15
chr2_+_25423234 3.135 ENSMUST00000134259.1
ENSMUST00000100320.4
Fut7

fucosyltransferase 7

chr15_+_39076885 3.116 ENSMUST00000067072.3
Cthrc1
collagen triple helix repeat containing 1
chr16_-_10395438 3.092 ENSMUST00000115831.1
Tekt5
tektin 5
chr1_+_165302625 3.082 ENSMUST00000111450.1
Gpr161
G protein-coupled receptor 161
chr14_-_51146757 3.070 ENSMUST00000080126.2
Rnase1
ribonuclease, RNase A family, 1 (pancreatic)
chr14_-_54686060 3.049 ENSMUST00000125265.1
Acin1
apoptotic chromatin condensation inducer 1
chr13_-_113100971 3.042 ENSMUST00000023897.5
Gzma
granzyme A
chr7_-_45239041 3.014 ENSMUST00000131290.1
Cd37
CD37 antigen
chr7_+_121865070 3.001 ENSMUST00000033161.5
Scnn1b
sodium channel, nonvoltage-gated 1 beta
chrX_+_73892102 3.001 ENSMUST00000033765.7
ENSMUST00000101470.2
ENSMUST00000114395.1
Avpr2


arginine vasopressin receptor 2


chr11_-_76577701 2.993 ENSMUST00000176179.1
Abr
active BCR-related gene
chr11_-_100414829 2.990 ENSMUST00000066489.6
Leprel4
leprecan-like 4
chrX_+_106027300 2.977 ENSMUST00000055941.6
Atp7a
ATPase, Cu++ transporting, alpha polypeptide
chr14_-_19977151 2.969 ENSMUST00000055100.7
ENSMUST00000162425.1
Gng2

guanine nucleotide binding protein (G protein), gamma 2

chr9_-_95815389 2.969 ENSMUST00000119760.1
Pls1
plastin 1 (I-isoform)
chr6_-_128826305 2.945 ENSMUST00000174544.1
ENSMUST00000172887.1
ENSMUST00000032472.4
Klrb1b


killer cell lectin-like receptor subfamily B member 1B



Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
17.4 52.3 GO:0002149 hypochlorous acid metabolic process(GO:0002148) hypochlorous acid biosynthetic process(GO:0002149)
11.4 34.1 GO:0002215 defense response to nematode(GO:0002215)
7.9 79.3 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
6.1 18.3 GO:0060217 hemangioblast cell differentiation(GO:0060217)
5.2 15.5 GO:0071613 granzyme B production(GO:0071613) regulation of granzyme B production(GO:0071661) positive regulation of granzyme B production(GO:0071663)
5.0 39.7 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
4.8 14.4 GO:2000872 positive regulation of progesterone secretion(GO:2000872)
4.2 20.9 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
3.7 14.8 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
3.3 16.7 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
3.1 9.2 GO:0002842 positive regulation of T cell mediated immune response to tumor cell(GO:0002842)
2.9 23.5 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
2.8 8.5 GO:0036292 DNA rewinding(GO:0036292)
2.3 6.8 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
2.0 8.1 GO:1902896 terminal web assembly(GO:1902896)
2.0 8.0 GO:0033380 protein localization to secretory granule(GO:0033366) protein localization to mast cell secretory granule(GO:0033367) protease localization to mast cell secretory granule(GO:0033368) maintenance of protein location in mast cell secretory granule(GO:0033370) T cell secretory granule organization(GO:0033371) maintenance of protease location in mast cell secretory granule(GO:0033373) protein localization to T cell secretory granule(GO:0033374) protease localization to T cell secretory granule(GO:0033375) maintenance of protein location in T cell secretory granule(GO:0033377) maintenance of protease location in T cell secretory granule(GO:0033379) granzyme B localization to T cell secretory granule(GO:0033380) maintenance of granzyme B location in T cell secretory granule(GO:0033382)
2.0 9.9 GO:0070103 regulation of interleukin-6-mediated signaling pathway(GO:0070103)
1.8 8.8 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
1.7 11.8 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
1.6 16.1 GO:0043313 regulation of neutrophil degranulation(GO:0043313)
1.6 3.2 GO:1903969 regulation of macrophage colony-stimulating factor signaling pathway(GO:1902226) regulation of response to macrophage colony-stimulating factor(GO:1903969) regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903972)
1.6 1.6 GO:0032672 regulation of interleukin-3 production(GO:0032672) positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401) positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
1.5 6.2 GO:0007056 spindle assembly involved in female meiosis(GO:0007056) positive regulation of oocyte development(GO:0060282) positive regulation of oogenesis(GO:1905881)
1.5 9.1 GO:0002457 T cell antigen processing and presentation(GO:0002457)
1.5 7.6 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
1.4 10.1 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
1.4 4.2 GO:1904959 elastin biosynthetic process(GO:0051542) regulation of electron carrier activity(GO:1904732) regulation of cytochrome-c oxidase activity(GO:1904959)
1.4 4.1 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
1.3 5.1 GO:0002540 leukotriene production involved in inflammatory response(GO:0002540)
1.3 10.1 GO:0035811 negative regulation of urine volume(GO:0035811)
1.3 3.8 GO:0060557 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
1.3 5.0 GO:0002767 immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
1.2 6.2 GO:1900275 negative regulation of phospholipase C activity(GO:1900275)
1.2 22.2 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
1.2 4.8 GO:0071352 interleukin-2-mediated signaling pathway(GO:0038110) cellular response to interleukin-2(GO:0071352)
1.2 5.9 GO:0061737 leukotriene signaling pathway(GO:0061737)
1.1 7.7 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
1.1 12.9 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
1.0 2.1 GO:0014732 skeletal muscle atrophy(GO:0014732)
1.0 11.2 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719)
1.0 2.9 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.9 11.3 GO:0034242 negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.9 2.7 GO:0051466 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) positive regulation of corticotropin-releasing hormone secretion(GO:0051466) regulation of G-protein coupled receptor internalization(GO:1904020)
0.9 2.7 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.9 10.8 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.9 2.7 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.9 7.2 GO:0015074 DNA integration(GO:0015074)
0.9 2.7 GO:0003127 detection of nodal flow(GO:0003127) detection of endogenous stimulus(GO:0009726)
0.9 2.7 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.8 2.5 GO:0071846 actin filament debranching(GO:0071846)
0.8 10.2 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.8 4.2 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.8 2.5 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.8 5.9 GO:0003011 involuntary skeletal muscle contraction(GO:0003011)
0.8 3.4 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726)
0.8 2.5 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.8 10.8 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.8 8.3 GO:0036376 sodium ion export from cell(GO:0036376)
0.8 2.5 GO:0072244 metanephric glomerular epithelium development(GO:0072244)
0.8 2.4 GO:0070844 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.8 10.6 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.8 3.2 GO:0014738 regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
0.8 1.5 GO:1904529 regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
0.7 3.7 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.7 2.2 GO:0090274 positive regulation of somatostatin secretion(GO:0090274)
0.7 2.9 GO:0071898 regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
0.7 2.1 GO:0043312 neutrophil degranulation(GO:0043312)
0.7 2.1 GO:2000016 negative regulation of determination of dorsal identity(GO:2000016)
0.7 9.2 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.7 4.2 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
0.7 3.4 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
0.7 2.7 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.7 2.7 GO:0120034 positive regulation of plasma membrane bounded cell projection assembly(GO:0120034)
0.7 8.0 GO:0043615 astrocyte cell migration(GO:0043615)
0.7 5.3 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.7 11.9 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.7 2.0 GO:0002355 detection of tumor cell(GO:0002355)
0.6 3.9 GO:0007412 axon target recognition(GO:0007412)
0.6 2.5 GO:2000612 regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.6 9.9 GO:0006657 CDP-choline pathway(GO:0006657)
0.6 1.8 GO:0042939 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.6 0.6 GO:2000642 negative regulation of cytoplasmic transport(GO:1903650) negative regulation of early endosome to late endosome transport(GO:2000642)
0.6 1.8 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.6 4.6 GO:1903575 cornified envelope assembly(GO:1903575)
0.6 1.7 GO:1905522 negative regulation of macrophage chemotaxis(GO:0010760) negative regulation of macrophage migration(GO:1905522)
0.6 0.6 GO:0032632 interleukin-3 production(GO:0032632)
0.5 1.6 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.5 2.2 GO:0044330 canonical Wnt signaling pathway involved in positive regulation of wound healing(GO:0044330) lactic acid secretion(GO:0046722) regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.5 2.6 GO:0009115 xanthine catabolic process(GO:0009115) xanthine metabolic process(GO:0046110)
0.5 2.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.5 2.0 GO:1902303 negative regulation of potassium ion export(GO:1902303)
0.5 4.4 GO:0010587 miRNA catabolic process(GO:0010587) positive regulation of cell proliferation involved in kidney development(GO:1901724)
0.5 1.9 GO:0002370 natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727)
0.5 3.9 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.5 4.8 GO:0030916 otic vesicle formation(GO:0030916)
0.5 1.4 GO:0045004 DNA replication proofreading(GO:0045004)
0.5 1.4 GO:0035771 interleukin-4-mediated signaling pathway(GO:0035771)
0.5 0.9 GO:0044413 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.5 1.9 GO:0070889 platelet alpha granule organization(GO:0070889)
0.5 6.5 GO:0071361 cellular response to ethanol(GO:0071361)
0.5 3.2 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.5 1.4 GO:0098763 mitotic cell cycle phase(GO:0098763)
0.5 1.8 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.4 1.8 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.4 10.2 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.4 3.5 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.4 4.3 GO:0000042 protein targeting to Golgi(GO:0000042)
0.4 8.5 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.4 2.5 GO:0046502 uroporphyrinogen III metabolic process(GO:0046502)
0.4 2.1 GO:0009597 detection of virus(GO:0009597)
0.4 5.4 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.4 1.2 GO:0019045 viral latency(GO:0019042) latent virus replication(GO:0019045) release from viral latency(GO:0019046)
0.4 1.2 GO:0016103 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.4 1.6 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.4 6.3 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.4 2.7 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.4 0.8 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.4 4.3 GO:0055064 chloride ion homeostasis(GO:0055064)
0.4 3.5 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.4 0.4 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.4 4.5 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.4 0.4 GO:0070858 negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
0.4 1.5 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.4 5.3 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.4 2.6 GO:0006108 malate metabolic process(GO:0006108)
0.4 0.7 GO:0010579 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.4 6.2 GO:0046069 cGMP catabolic process(GO:0046069)
0.4 2.5 GO:0006561 proline biosynthetic process(GO:0006561)
0.4 2.1 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.3 2.8 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.3 2.1 GO:0007144 female meiosis I(GO:0007144)
0.3 2.4 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.3 5.0 GO:0046514 ceramide catabolic process(GO:0046514)
0.3 0.7 GO:2000501 natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501) positive regulation of natural killer cell chemotaxis(GO:2000503)
0.3 7.8 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.3 1.6 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.3 1.3 GO:0046898 response to cycloheximide(GO:0046898)
0.3 1.3 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.3 0.6 GO:1905863 invadopodium organization(GO:1905863)
0.3 5.0 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.3 0.9 GO:0071374 cellular response to parathyroid hormone stimulus(GO:0071374)
0.3 2.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.3 1.8 GO:0010626 negative regulation of Schwann cell proliferation(GO:0010626)
0.3 0.3 GO:0036006 response to macrophage colony-stimulating factor(GO:0036005) cellular response to macrophage colony-stimulating factor stimulus(GO:0036006)
0.3 3.0 GO:0015879 carnitine transport(GO:0015879)
0.3 6.1 GO:0033033 negative regulation of myeloid cell apoptotic process(GO:0033033)
0.3 4.9 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.3 5.2 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.3 0.9 GO:0061642 chemoattraction of axon(GO:0061642) inner medullary collecting duct development(GO:0072061)
0.3 2.0 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.3 0.8 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.3 1.4 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.3 3.1 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.3 0.5 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.3 1.1 GO:0003349 epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
0.3 1.3 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.3 1.9 GO:0042148 strand invasion(GO:0042148)
0.3 0.8 GO:2000321 positive regulation of T-helper 17 cell differentiation(GO:2000321)
0.3 2.1 GO:0050665 hydrogen peroxide biosynthetic process(GO:0050665)
0.3 4.8 GO:0001911 negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.2 1.2 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.2 2.7 GO:1901299 negative regulation of hydrogen peroxide-mediated programmed cell death(GO:1901299)
0.2 1.9 GO:0019244 lactate biosynthetic process from pyruvate(GO:0019244)
0.2 1.5 GO:0015722 canalicular bile acid transport(GO:0015722)
0.2 3.1 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
0.2 0.5 GO:0071873 response to norepinephrine(GO:0071873)
0.2 1.4 GO:0050917 sensory perception of umami taste(GO:0050917)
0.2 1.9 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.2 2.1 GO:0000733 DNA strand renaturation(GO:0000733)
0.2 0.5 GO:0001805 type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805)
0.2 1.4 GO:0035624 receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
0.2 7.9 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.2 0.7 GO:0021972 corticospinal neuron axon guidance through spinal cord(GO:0021972) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
0.2 2.3 GO:0072540 T-helper 17 cell lineage commitment(GO:0072540)
0.2 0.9 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.2 6.2 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.2 4.9 GO:0007614 short-term memory(GO:0007614)
0.2 0.7 GO:0006550 isoleucine catabolic process(GO:0006550)
0.2 1.7 GO:0016576 histone dephosphorylation(GO:0016576)
0.2 0.4 GO:0042322 negative regulation of circadian sleep/wake cycle, REM sleep(GO:0042322)
0.2 7.0 GO:0000303 response to superoxide(GO:0000303)
0.2 2.7 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.2 1.2 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.2 2.7 GO:0048733 sebaceous gland development(GO:0048733)
0.2 2.2 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.2 2.4 GO:0021780 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.2 2.8 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.2 0.6 GO:0060126 somatotropin secreting cell differentiation(GO:0060126)
0.2 2.0 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.2 5.3 GO:0010714 positive regulation of collagen metabolic process(GO:0010714) positive regulation of collagen biosynthetic process(GO:0032967) positive regulation of multicellular organismal metabolic process(GO:0044253)
0.2 5.4 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.2 3.7 GO:0003351 epithelial cilium movement(GO:0003351)
0.2 18.1 GO:0042100 B cell proliferation(GO:0042100)
0.2 1.3 GO:2001015 negative regulation of skeletal muscle cell differentiation(GO:2001015)
0.2 0.7 GO:0046719 regulation by virus of viral protein levels in host cell(GO:0046719) positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.2 3.0 GO:0035313 wound healing, spreading of epidermal cells(GO:0035313)
0.2 1.1 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.2 0.8 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.2 0.5 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264) negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.2 0.9 GO:0006543 glutamine catabolic process(GO:0006543)
0.2 0.5 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.2 5.0 GO:0032094 response to food(GO:0032094)
0.2 0.8 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.2 1.4 GO:0051195 negative regulation of glycolytic process(GO:0045820) negative regulation of cofactor metabolic process(GO:0051195) negative regulation of coenzyme metabolic process(GO:0051198)
0.1 0.4 GO:0072236 metanephric loop of Henle development(GO:0072236)
0.1 1.3 GO:0098907 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) regulation of SA node cell action potential(GO:0098907)
0.1 0.7 GO:0061589 calcium activated phosphatidylserine scrambling(GO:0061589)
0.1 1.3 GO:0032261 purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264)
0.1 0.9 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.1 0.6 GO:1990928 response to amino acid starvation(GO:1990928)
0.1 0.6 GO:0009212 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) dTTP metabolic process(GO:0046075)
0.1 2.0 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.1 0.6 GO:0019509 L-methionine salvage from methylthioadenosine(GO:0019509)
0.1 1.1 GO:1900118 negative regulation of execution phase of apoptosis(GO:1900118)
0.1 0.8 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1 0.4 GO:0015819 lysine transport(GO:0015819)
0.1 0.7 GO:1990034 calcium ion export from cell(GO:1990034)
0.1 3.2 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.1 0.7 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.1 3.8 GO:0032720 negative regulation of tumor necrosis factor production(GO:0032720)
0.1 1.3 GO:0097084 vascular smooth muscle cell development(GO:0097084)
0.1 0.9 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.1 0.7 GO:0051684 maintenance of Golgi location(GO:0051684)
0.1 5.6 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1 2.7 GO:1900153 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.1 0.5 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689)
0.1 1.6 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.5 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199) endocardial cushion to mesenchymal transition(GO:0090500)
0.1 0.9 GO:0001757 somite specification(GO:0001757)
0.1 1.0 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1 4.1 GO:0019236 response to pheromone(GO:0019236)
0.1 1.5 GO:0038092 nodal signaling pathway(GO:0038092)
0.1 2.0 GO:0051382 kinetochore assembly(GO:0051382)
0.1 2.6 GO:0106030 axonal fasciculation(GO:0007413) neuron projection fasciculation(GO:0106030)
0.1 0.5 GO:0072675 osteoclast fusion(GO:0072675)
0.1 1.9 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.1 2.6 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.1 2.4 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.1 1.6 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.1 0.3 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.1 14.9 GO:0045667 regulation of osteoblast differentiation(GO:0045667)
0.1 0.6 GO:1900095 regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.1 4.7 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.1 1.8 GO:0002335 mature B cell differentiation(GO:0002335)
0.1 4.9 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.1 0.5 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.1 0.7 GO:0030007 cellular potassium ion homeostasis(GO:0030007)
0.1 0.3 GO:0042791 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791)
0.1 1.2 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.1 0.9 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 0.3 GO:0060697 positive regulation of phospholipid catabolic process(GO:0060697)
0.1 0.2 GO:0035483 gastric emptying(GO:0035483)
0.1 0.7 GO:2000143 negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.1 2.6 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.1 2.9 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.1 0.3 GO:0019085 early viral transcription(GO:0019085)
0.1 1.1 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.1 0.5 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.1 5.4 GO:0033619 membrane protein proteolysis(GO:0033619)
0.1 0.4 GO:2001204 regulation of osteoclast development(GO:2001204)
0.1 0.9 GO:0051013 microtubule severing(GO:0051013)
0.1 2.4 GO:1904659 glucose transmembrane transport(GO:1904659)
0.1 0.3 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.1 2.1 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.1 4.0 GO:0035137 hindlimb morphogenesis(GO:0035137)
0.1 1.0 GO:2000678 negative regulation of transcription regulatory region DNA binding(GO:2000678)
0.1 0.6 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 1.8 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.1 0.4 GO:0015676 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.1 0.8 GO:0070571 negative regulation of neuron projection regeneration(GO:0070571)
0.1 2.5 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 1.7 GO:0072678 T cell migration(GO:0072678)
0.1 1.1 GO:0050716 regulation of interleukin-1 secretion(GO:0050704) regulation of interleukin-1 beta secretion(GO:0050706) positive regulation of interleukin-1 secretion(GO:0050716) positive regulation of interleukin-1 beta secretion(GO:0050718)
0.1 0.2 GO:2000969 positive regulation of AMPA receptor activity(GO:2000969)
0.1 0.7 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.1 0.3 GO:0021660 rhombomere morphogenesis(GO:0021593) rhombomere formation(GO:0021594) rhombomere 3 morphogenesis(GO:0021658) rhombomere 3 formation(GO:0021660) rhombomere 5 morphogenesis(GO:0021664) rhombomere 5 formation(GO:0021666)
0.1 1.2 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.1 1.6 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1 0.4 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.1 0.6 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 0.5 GO:0098909 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.1 0.3 GO:0002159 desmosome assembly(GO:0002159)
0.1 0.7 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.1 0.5 GO:0033603 positive regulation of dopamine secretion(GO:0033603)
0.1 0.5 GO:0036506 maintenance of unfolded protein(GO:0036506) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.1 0.8 GO:0098664 serotonin receptor signaling pathway(GO:0007210) G-protein coupled serotonin receptor signaling pathway(GO:0098664)
0.1 7.2 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1 0.1 GO:1900623 positive regulation of mast cell cytokine production(GO:0032765) monocyte aggregation(GO:0070487) regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.1 0.3 GO:0061188 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.1 1.4 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 3.3 GO:0060291 long-term synaptic potentiation(GO:0060291)
0.1 1.8 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.1 0.2 GO:0021506 anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)
0.1 0.4 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.1 0.2 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.1 0.7 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336)
0.1 3.1 GO:0010771 negative regulation of cell morphogenesis involved in differentiation(GO:0010771)
0.1 1.0 GO:0032674 regulation of interleukin-5 production(GO:0032674)
0.1 0.8 GO:0031032 actomyosin structure organization(GO:0031032)
0.1 0.1 GO:0014010 Schwann cell proliferation(GO:0014010)
0.1 0.3 GO:0060214 endocardium formation(GO:0060214)
0.1 2.1 GO:0070527 platelet aggregation(GO:0070527)
0.0 0.7 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.0 3.3 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.2 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.8 GO:2000369 regulation of clathrin-dependent endocytosis(GO:2000369)
0.0 2.6 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.9 GO:0016180 snRNA processing(GO:0016180)
0.0 6.2 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 1.7 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 1.7 GO:0003341 cilium movement(GO:0003341)
0.0 0.9 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.0 0.8 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.8 GO:0036065 fucosylation(GO:0036065)
0.0 1.5 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.7 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.3 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.5 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 1.6 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 2.6 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.3 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.2 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.0 0.7 GO:0046037 GMP metabolic process(GO:0046037)
0.0 0.9 GO:0043967 histone H4 acetylation(GO:0043967)
0.0 0.6 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.1 GO:0040030 regulation of molecular function, epigenetic(GO:0040030)
0.0 0.8 GO:0060009 Sertoli cell development(GO:0060009)
0.0 1.7 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.1 GO:0060536 growth plate cartilage chondrocyte differentiation(GO:0003418) cartilage morphogenesis(GO:0060536)
0.0 0.6 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.2 GO:0007296 vitellogenesis(GO:0007296)
0.0 1.3 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.7 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.4 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.1 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.0 0.3 GO:1900003 regulation of serine-type endopeptidase activity(GO:1900003) negative regulation of serine-type endopeptidase activity(GO:1900004) regulation of serine-type peptidase activity(GO:1902571) negative regulation of serine-type peptidase activity(GO:1902572)
0.0 0.7 GO:0033006 regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)
0.0 0.4 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 1.7 GO:0008088 axo-dendritic transport(GO:0008088)
0.0 6.9 GO:0022412 cellular process involved in reproduction in multicellular organism(GO:0022412)
0.0 0.8 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.0 0.8 GO:0035904 aorta development(GO:0035904)
0.0 1.0 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.0 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.0 0.1 GO:0038007 anterior/posterior axon guidance(GO:0033564) netrin-activated signaling pathway(GO:0038007)
0.0 0.2 GO:0010667 negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0 1.3 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 1.3 GO:0043473 pigmentation(GO:0043473)
0.0 0.9 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.3 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.2 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 0.1 GO:0048665 neuron fate specification(GO:0048665)
0.0 0.1 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
0.0 0.6 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.2 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.2 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.2 GO:0035411 catenin import into nucleus(GO:0035411)
0.0 0.6 GO:0071772 response to BMP(GO:0071772) cellular response to BMP stimulus(GO:0071773)
0.0 0.6 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 0.1 GO:0006661 phosphatidylinositol biosynthetic process(GO:0006661)
0.0 0.2 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.2 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.7 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 0.1 GO:0002418 immune response to tumor cell(GO:0002418)
0.0 0.2 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.3 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
17.7 70.7 GO:0070442 integrin alphaIIb-beta3 complex(GO:0070442)
6.1 18.3 GO:0033193 Lsd1/2 complex(GO:0033193)
4.2 16.8 GO:0044194 cytolytic granule(GO:0044194)
4.0 63.7 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
2.1 6.2 GO:0042585 germinal vesicle(GO:0042585)
1.8 5.3 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
1.7 8.6 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
1.5 18.9 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
1.1 3.3 GO:0070557 PCNA-p21 complex(GO:0070557)
1.1 15.1 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
1.0 11.8 GO:0071439 clathrin complex(GO:0071439)
0.9 2.8 GO:1990423 RZZ complex(GO:1990423)
0.9 8.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.9 6.9 GO:1990357 terminal web(GO:1990357)
0.8 2.5 GO:0046691 intracellular canaliculus(GO:0046691)
0.7 3.0 GO:0031084 BLOC-2 complex(GO:0031084)
0.7 2.8 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.7 7.0 GO:0042581 specific granule(GO:0042581)
0.7 4.9 GO:0019815 B cell receptor complex(GO:0019815)
0.7 17.7 GO:0031528 microvillus membrane(GO:0031528)
0.7 7.4 GO:0097208 alveolar lamellar body(GO:0097208)
0.6 2.5 GO:0060187 cell pole(GO:0060187)
0.6 1.8 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.6 8.1 GO:0005884 actin filament(GO:0005884)
0.6 1.7 GO:0033186 CAF-1 complex(GO:0033186)
0.6 0.6 GO:0070820 tertiary granule(GO:0070820)
0.6 2.8 GO:0042583 chromaffin granule(GO:0042583)
0.5 2.1 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.5 2.0 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.5 6.1 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
0.5 1.4 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.5 7.3 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.4 4.9 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.4 4.8 GO:0031080 nuclear pore outer ring(GO:0031080)
0.4 11.7 GO:0042588 zymogen granule(GO:0042588)
0.4 2.1 GO:0036379 myofilament(GO:0036379)
0.4 3.7 GO:0061574 ASAP complex(GO:0061574)
0.4 2.0 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.4 1.1 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.4 4.2 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.3 1.3 GO:0060077 inhibitory synapse(GO:0060077)
0.3 0.9 GO:1990047 spindle matrix(GO:1990047)
0.3 9.5 GO:0097228 sperm principal piece(GO:0097228)
0.3 1.2 GO:0090537 CERF complex(GO:0090537)
0.3 2.7 GO:0034709 methylosome(GO:0034709)
0.3 3.8 GO:0097512 cardiac myofibril(GO:0097512)
0.3 0.8 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.2 0.7 GO:0030905 retromer, tubulation complex(GO:0030905)
0.2 2.0 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.2 0.7 GO:0005608 laminin-3 complex(GO:0005608)
0.2 4.6 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285)
0.2 2.7 GO:0035686 sperm fibrous sheath(GO:0035686)
0.2 1.6 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.2 0.8 GO:0034687 integrin alphaL-beta2 complex(GO:0034687)
0.2 2.1 GO:0043020 NADPH oxidase complex(GO:0043020)
0.2 0.9 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.2 9.8 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.2 1.1 GO:0033010 paranodal junction(GO:0033010)
0.2 0.9 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.2 0.9 GO:1990761 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.2 1.2 GO:0005638 lamin filament(GO:0005638)
0.2 10.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834) GTPase complex(GO:1905360)
0.2 4.2 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.2 2.4 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.2 0.9 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.2 0.6 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.2 1.4 GO:0097165 nuclear stress granule(GO:0097165)
0.2 0.8 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 0.7 GO:0099524 region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524)
0.1 1.3 GO:0030018 Z disc(GO:0030018) I band(GO:0031674)
0.1 9.9 GO:0005844 polysome(GO:0005844)
0.1 7.6 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 6.0 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 0.9 GO:0097255 R2TP complex(GO:0097255)
0.1 26.5 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.1 1.6 GO:0031209 SCAR complex(GO:0031209)
0.1 3.8 GO:0032590 dendrite membrane(GO:0032590)
0.1 2.4 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.1 1.6 GO:0005861 troponin complex(GO:0005861)
0.1 1.8 GO:0030056 hemidesmosome(GO:0030056)
0.1 1.5 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 0.4 GO:0071007 U2-type catalytic step 2 spliceosome(GO:0071007)
0.1 1.5 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.1 1.3 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 0.6 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.1 2.8 GO:0008305 integrin complex(GO:0008305)
0.1 12.9 GO:0005604 basement membrane(GO:0005604)
0.1 0.8 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.1 2.0 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 6.3 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 2.8 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 2.1 GO:0001673 male germ cell nucleus(GO:0001673)
0.1 0.7 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 10.6 GO:0016363 nuclear matrix(GO:0016363)
0.1 1.4 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 2.3 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.1 0.8 GO:0072687 meiotic spindle(GO:0072687)
0.1 2.4 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.1 0.3 GO:0005914 spot adherens junction(GO:0005914)
0.1 1.7 GO:0035253 ciliary rootlet(GO:0035253)
0.1 1.9 GO:0010369 chromocenter(GO:0010369)
0.1 14.3 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 1.1 GO:0061702 inflammasome complex(GO:0061702)
0.1 2.9 GO:0097440 apical dendrite(GO:0097440)
0.1 0.4 GO:0070826 paraferritin complex(GO:0070826)
0.1 2.2 GO:0034706 sodium channel complex(GO:0034706)
0.1 1.3 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 0.3 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.1 1.3 GO:0032433 filopodium tip(GO:0032433)
0.1 0.5 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1 1.7 GO:0030137 COPI-coated vesicle(GO:0030137)
0.1 0.2 GO:0043512 inhibin A complex(GO:0043512)
0.1 3.9 GO:1904115 axon cytoplasm(GO:1904115)
0.1 1.4 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 0.9 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 11.7 GO:0032993 protein-DNA complex(GO:0032993)
0.1 2.0 GO:0031902 late endosome membrane(GO:0031902)
0.1 0.8 GO:0005869 dynactin complex(GO:0005869)
0.1 7.3 GO:0030139 endocytic vesicle(GO:0030139)
0.1 0.3 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.1 2.0 GO:0016235 aggresome(GO:0016235)
0.1 10.1 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.1 0.7 GO:0034719 SMN complex(GO:0032797) SMN-Sm protein complex(GO:0034719)
0.1 4.3 GO:0072686 mitotic spindle(GO:0072686)
0.1 2.5 GO:0031941 filamentous actin(GO:0031941)
0.1 0.6 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 6.6 GO:0043204 perikaryon(GO:0043204)
0.1 2.3 GO:0005871 kinesin complex(GO:0005871)
0.1 12.7 GO:0012506 vesicle membrane(GO:0012506)
0.1 0.9 GO:0032039 integrator complex(GO:0032039)
0.1 0.5 GO:0032982 myosin filament(GO:0032982)
0.1 0.7 GO:0043194 axon initial segment(GO:0043194)
0.0 1.2 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 1.9 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.4 GO:0000243 commitment complex(GO:0000243)
0.0 1.6 GO:0031519 PcG protein complex(GO:0031519)
0.0 14.3 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.3 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.2 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.3 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.5 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.4 GO:0044306 axon terminus(GO:0043679) neuron projection terminus(GO:0044306)
0.0 3.6 GO:0036157 outer dynein arm(GO:0036157)
0.0 6.3 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.2 GO:0042734 presynaptic membrane(GO:0042734)
0.0 4.4 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.9 GO:0005902 microvillus(GO:0005902)
0.0 1.2 GO:0043034 costamere(GO:0043034)
0.0 2.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.3 GO:0034704 calcium channel complex(GO:0034704)
0.0 2.0 GO:0005581 collagen trimer(GO:0005581)
0.0 1.3 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.9 GO:0008180 COP9 signalosome(GO:0008180)
0.0 2.0 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.5 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.0 4.3 GO:0005912 adherens junction(GO:0005912)
0.0 0.5 GO:0016234 inclusion body(GO:0016234)
0.0 1.2 GO:0030027 lamellipodium(GO:0030027)
0.0 1.8 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 2.4 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 0.3 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 0.3 GO:0030117 membrane coat(GO:0030117) coated membrane(GO:0048475)
0.0 0.2 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 0.8 GO:0042629 mast cell granule(GO:0042629)
0.0 0.2 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.6 GO:0000502 proteasome complex(GO:0000502) endopeptidase complex(GO:1905369)
0.0 0.4 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.0 6.2 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 2.5 GO:0005681 spliceosomal complex(GO:0005681)
0.0 0.5 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 2.0 GO:0030426 growth cone(GO:0030426)
0.0 0.1 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.4 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.5 GO:0005921 gap junction(GO:0005921)
0.0 0.2 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.3 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 1.6 GO:0019898 extrinsic component of membrane(GO:0019898)
0.0 0.1 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 41.0 GO:0005615 extracellular space(GO:0005615)
0.0 0.4 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 1.0 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 1.1 GO:0005819 spindle(GO:0005819)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 12.6 GO:0031721 haptoglobin binding(GO:0031720) hemoglobin alpha binding(GO:0031721)
2.9 23.5 GO:0002951 leukotriene-C(4) hydrolase(GO:0002951)
2.7 43.5 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
2.2 28.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
2.0 9.9 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
1.9 14.8 GO:0033691 sialic acid binding(GO:0033691)
1.8 16.0 GO:0008865 fructokinase activity(GO:0008865)
1.8 7.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
1.7 8.5 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
1.6 4.8 GO:0004911 interleukin-2 receptor activity(GO:0004911)
1.5 1.5 GO:0019976 interleukin-2 binding(GO:0019976)
1.4 4.2 GO:0045352 interleukin-1, Type II receptor binding(GO:0005151) interleukin-1 Type I receptor antagonist activity(GO:0045352) interleukin-1 Type II receptor antagonist activity(GO:0045353)
1.4 5.5 GO:0004974 leukotriene receptor activity(GO:0004974)
1.3 13.5 GO:0004498 calcidiol 1-monooxygenase activity(GO:0004498)
1.3 82.1 GO:0004601 peroxidase activity(GO:0004601)
1.3 3.9 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
1.3 3.8 GO:0004771 sterol esterase activity(GO:0004771) retinyl-palmitate esterase activity(GO:0050253)
1.2 8.1 GO:0046624 sphingolipid transporter activity(GO:0046624)
1.1 8.0 GO:0004027 alcohol sulfotransferase activity(GO:0004027)
1.1 3.3 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
1.1 3.2 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
1.1 4.3 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
1.1 4.2 GO:0043682 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
0.9 2.7 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.9 14.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.9 2.7 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.9 1.7 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.9 2.6 GO:0004473 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.8 3.4 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.8 10.8 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.8 2.3 GO:0004051 arachidonate 5-lipoxygenase activity(GO:0004051)
0.8 2.3 GO:0034617 tetrahydrobiopterin binding(GO:0034617)
0.7 5.2 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.7 8.0 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.7 12.3 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.7 2.1 GO:0070615 nucleosome-dependent ATPase activity(GO:0070615)
0.6 3.2 GO:1990254 keratin filament binding(GO:1990254)
0.6 2.4 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.6 9.7 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.6 8.3 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.5 2.6 GO:0004854 xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726)
0.5 3.1 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.5 1.6 GO:0052593 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.5 3.0 GO:0004111 creatine kinase activity(GO:0004111)
0.5 3.0 GO:0005124 scavenger receptor binding(GO:0005124)
0.5 1.4 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.5 2.8 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.5 1.4 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938) epinephrine binding(GO:0051379)
0.5 4.1 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.5 5.4 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.5 1.8 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.4 22.8 GO:0005158 insulin receptor binding(GO:0005158)
0.4 3.6 GO:0048495 Roundabout binding(GO:0048495)
0.4 3.1 GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.4 3.4 GO:0045545 syndecan binding(GO:0045545)
0.4 2.1 GO:0070051 fibrinogen binding(GO:0070051)
0.4 2.9 GO:0031013 troponin I binding(GO:0031013)
0.4 4.0 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.4 8.5 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.4 2.0 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.4 1.6 GO:0019767 IgE receptor activity(GO:0019767)
0.4 0.8 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.4 1.9 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.4 3.0 GO:0005000 vasopressin receptor activity(GO:0005000)
0.4 2.6 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.4 4.4 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.4 2.5 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.4 13.5 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.4 7.8 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.4 15.5 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.3 2.0 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.3 19.5 GO:0070888 E-box binding(GO:0070888)
0.3 3.0 GO:0070061 fructose binding(GO:0070061)
0.3 2.7 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.3 8.7 GO:0043274 phospholipase binding(GO:0043274)
0.3 0.7 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.3 1.6 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.3 2.0 GO:0071723 lipopeptide binding(GO:0071723)
0.3 1.0 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.3 5.3 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol trisphosphate phosphatase activity(GO:0046030)
0.3 5.6 GO:0050811 GABA receptor binding(GO:0050811)
0.3 2.1 GO:0098821 BMP receptor activity(GO:0098821)
0.3 1.5 GO:0038100 nodal binding(GO:0038100)
0.3 8.4 GO:0008009 chemokine activity(GO:0008009)
0.3 1.8 GO:1990932 5.8S rRNA binding(GO:1990932)
0.3 9.7 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.3 4.1 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.3 5.5 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.3 4.5 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.3 2.0 GO:0030284 estrogen receptor activity(GO:0030284)
0.3 6.1 GO:0001618 virus receptor activity(GO:0001618)
0.3 1.9 GO:0000150 recombinase activity(GO:0000150)
0.3 0.8 GO:0008107 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.3 1.6 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.2 5.7 GO:0031005 filamin binding(GO:0031005)
0.2 6.4 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.2 1.2 GO:0052795 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.2 2.2 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.2 0.7 GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
0.2 4.2 GO:0035174 histone serine kinase activity(GO:0035174)
0.2 0.9 GO:0001847 opsonin receptor activity(GO:0001847)
0.2 2.0 GO:0045499 chemorepellent activity(GO:0045499)
0.2 2.4 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.2 0.9 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
0.2 1.5 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.2 9.4 GO:0050699 WW domain binding(GO:0050699)
0.2 1.0 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.2 0.8 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.2 0.6 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.2 2.4 GO:0070097 delta-catenin binding(GO:0070097)
0.2 1.5 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.2 1.1 GO:0035827 rubidium ion transmembrane transporter activity(GO:0035827)
0.2 0.9 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.2 1.1 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.2 3.9 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.2 2.2 GO:0005522 profilin binding(GO:0005522)
0.2 0.9 GO:0019864 IgG binding(GO:0019864)
0.2 4.8 GO:0016503 pheromone receptor activity(GO:0016503)
0.2 3.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.2 2.1 GO:0043522 leucine zipper domain binding(GO:0043522)
0.2 12.6 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.2 0.7 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.2 1.7 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.2 1.7 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.2 4.1 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.2 2.1 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.2 0.9 GO:0004359 glutaminase activity(GO:0004359)
0.2 0.9 GO:0097643 amylin receptor activity(GO:0097643)
0.2 0.9 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.2 1.5 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.2 27.5 GO:0017124 SH3 domain binding(GO:0017124)
0.2 0.9 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.2 0.5 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.2 8.7 GO:0004743 phosphoglycerate kinase activity(GO:0004618) phosphoglycerate mutase activity(GO:0004619) pyruvate kinase activity(GO:0004743)
0.1 1.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) phosphatidylinositol-3,5-bisphosphate phosphatase activity(GO:0106018)
0.1 1.3 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 2.1 GO:0015250 water channel activity(GO:0015250)
0.1 1.1 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 0.9 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 2.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 1.9 GO:0005243 gap junction channel activity(GO:0005243)
0.1 1.3 GO:0051434 BH3 domain binding(GO:0051434)
0.1 1.3 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.1 1.3 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 0.9 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 0.5 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
0.1 0.7 GO:0005499 vitamin D binding(GO:0005499)
0.1 4.5 GO:0001784 phosphotyrosine residue binding(GO:0001784)
0.1 2.2 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 3.7 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 4.7 GO:0003785 actin monomer binding(GO:0003785)
0.1 1.6 GO:0005523 tropomyosin binding(GO:0005523)
0.1 6.4 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.1 1.6 GO:0005123 death receptor binding(GO:0005123)
0.1 2.3 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 3.5 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 4.2 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 14.6 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 0.4 GO:0046848 hydroxyapatite binding(GO:0046848)
0.1 0.5 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.1 0.7 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.1 0.3 GO:0001003 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003)
0.1 0.5 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.1 2.9 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 0.4 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.1 0.7 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.1 0.7 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity(GO:0004114)
0.1 1.0 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.1 3.1 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 13.2 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 0.5 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 1.4 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.1 1.1 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.7 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.1 0.8 GO:1990446 U1 snRNP binding(GO:1990446)
0.1 1.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907) G-protein coupled neurotransmitter receptor activity(GO:0099528)
0.1 1.1 GO:0097110 scaffold protein binding(GO:0097110)
0.1 0.3 GO:0070976 calcium-independent protein kinase C activity(GO:0004699) TIR domain binding(GO:0070976)
0.1 1.2 GO:0016918 retinal binding(GO:0016918)
0.1 9.1 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.1 4.2 GO:0001540 amyloid-beta binding(GO:0001540)
0.1 0.4 GO:0015189 L-ornithine transmembrane transporter activity(GO:0000064) L-lysine transmembrane transporter activity(GO:0015189)
0.1 0.7 GO:0031432 titin binding(GO:0031432)
0.1 0.6 GO:0001614 purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502) purinergic receptor activity(GO:0035586)
0.1 0.7 GO:0008527 taste receptor activity(GO:0008527)
0.1 0.4 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 0.8 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 4.1 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 2.3 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 0.9 GO:0001163 RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.1 0.2 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
0.1 0.1 GO:0004637 phosphoribosylamine-glycine ligase activity(GO:0004637)
0.1 0.9 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 5.3 GO:0005518 collagen binding(GO:0005518)
0.1 7.8 GO:0002020 protease binding(GO:0002020)
0.1 0.5 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.1 5.0 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.1 0.3 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 1.5 GO:0042288 MHC class I protein binding(GO:0042288)
0.1 0.8 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.1 0.5 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 1.7 GO:0045503 dynein light chain binding(GO:0045503)
0.1 3.4 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.1 0.6 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.1 16.7 GO:0005096 GTPase activator activity(GO:0005096)
0.1 4.0 GO:0003777 microtubule motor activity(GO:0003777)
0.1 0.7 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 0.6 GO:0002162 dystroglycan binding(GO:0002162)
0.1 18.5 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 2.4 GO:0032452 histone demethylase activity(GO:0032452)
0.1 1.5 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 1.1 GO:0001056 RNA polymerase III activity(GO:0001056)
0.1 0.9 GO:0070577 lysine-acetylated histone binding(GO:0070577) acetylation-dependent protein binding(GO:0140033)
0.1 6.8 GO:0042826 histone deacetylase binding(GO:0042826)
0.1 0.3 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.2 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 5.6 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 1.6 GO:0003774 motor activity(GO:0003774)
0.0 0.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 1.2 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 1.8 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 11.8 GO:0030246 carbohydrate binding(GO:0030246)
0.0 1.3 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 1.7 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 0.8 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.7 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.7 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.5 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.3 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.3 GO:0035197 siRNA binding(GO:0035197)
0.0 1.7 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 2.9 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.8 GO:0005112 Notch binding(GO:0005112)
0.0 3.9 GO:0008047 enzyme activator activity(GO:0008047)
0.0 0.3 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 2.6 GO:0015297 antiporter activity(GO:0015297)
0.0 0.0 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.2 GO:0070699 inhibin binding(GO:0034711) type II activin receptor binding(GO:0070699)
0.0 2.5 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 2.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.7 GO:0030695 GTPase regulator activity(GO:0030695)
0.0 0.3 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 3.8 GO:0044325 ion channel binding(GO:0044325)
0.0 1.7 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.1 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 1.5 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 1.3 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.1 GO:0008988 rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) U6 snRNA 3'-end binding(GO:0030629)
0.0 0.8 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164) tumor necrosis factor receptor superfamily binding(GO:0032813)
0.0 3.2 GO:0008301 DNA binding, bending(GO:0008301)
0.0 1.0 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.2 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.3 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 6.1 GO:0005543 phospholipid binding(GO:0005543)
0.0 0.1 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.2 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.3 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.6 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.6 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 1.2 GO:0051015 actin filament binding(GO:0051015)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 60.8 PID_IL23_PATHWAY IL23-mediated signaling events
0.8 14.8 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.8 13.7 SA_G1_AND_S_PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.7 23.3 PID_AR_NONGENOMIC_PATHWAY Nongenotropic Androgen signaling
0.6 23.3 PID_EPO_PATHWAY EPO signaling pathway
0.6 34.6 PID_IL12_2PATHWAY IL12-mediated signaling events
0.5 36.1 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.5 9.8 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.4 22.8 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.4 14.4 PID_KIT_PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.4 9.5 PID_CXCR3_PATHWAY CXCR3-mediated signaling events
0.4 7.5 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.4 9.9 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.3 1.9 PID_EPHA2_FWD_PATHWAY EPHA2 forward signaling
0.3 7.7 PID_ARF6_PATHWAY Arf6 signaling events
0.3 2.6 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events
0.2 7.7 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.2 1.9 PID_VEGFR1_PATHWAY VEGFR1 specific signals
0.2 9.9 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.2 5.9 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.2 6.0 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.2 5.6 PID_BARD1_PATHWAY BARD1 signaling events
0.2 2.5 PID_TCPTP_PATHWAY Signaling events mediated by TCPTP
0.2 1.8 PID_S1P_S1P1_PATHWAY S1P1 pathway
0.2 4.3 PID_IL1_PATHWAY IL1-mediated signaling events
0.2 3.5 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.2 5.3 PID_RAS_PATHWAY Regulation of Ras family activation
0.2 5.9 PID_BCR_5PATHWAY BCR signaling pathway
0.1 13.3 PID_PDGFRB_PATHWAY PDGFR-beta signaling pathway
0.1 4.2 PID_AMB2_NEUTROPHILS_PATHWAY amb2 Integrin signaling
0.1 12.5 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.1 2.9 PID_FCER1_PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 7.8 ST_INTEGRIN_SIGNALING_PATHWAY Integrin Signaling Pathway
0.1 0.8 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.1 1.7 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.1 1.8 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 3.1 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.1 19.3 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 1.0 PID_IL5_PATHWAY IL5-mediated signaling events
0.1 2.2 PID_RAC1_PATHWAY RAC1 signaling pathway
0.1 6.4 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.1 1.9 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.1 2.0 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.1 2.1 PID_RHOA_PATHWAY RhoA signaling pathway
0.1 0.6 PID_INTEGRIN_CS_PATHWAY Integrin family cell surface interactions
0.1 1.0 PID_FAK_PATHWAY Signaling events mediated by focal adhesion kinase
0.1 2.8 PID_ERBB1_DOWNSTREAM_PATHWAY ErbB1 downstream signaling
0.1 1.6 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 6.3 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 2.8 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.1 1.4 PID_EPHB_FWD_PATHWAY EPHB forward signaling
0.1 0.7 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 2.9 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.1 1.4 PID_ERBB4_PATHWAY ErbB4 signaling events
0.1 2.5 PID_E2F_PATHWAY E2F transcription factor network
0.1 1.4 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.1 0.7 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.1 2.9 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.1 2.7 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.1 2.1 PID_BMP_PATHWAY BMP receptor signaling
0.0 0.9 PID_SHP2_PATHWAY SHP2 signaling
0.0 2.0 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.0 1.4 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.0 0.9 PID_TNF_PATHWAY TNF receptor signaling pathway
0.0 0.2 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.6 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.0 0.3 ST_B_CELL_ANTIGEN_RECEPTOR B Cell Antigen Receptor
0.0 0.4 PID_CXCR4_PATHWAY CXCR4-mediated signaling events
0.0 0.6 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 0.3 ST_ADRENERGIC Adrenergic Pathway
0.0 0.3 ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 1.5 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.1 PID_TRAIL_PATHWAY TRAIL signaling pathway
0.0 0.1 PID_ALK2_PATHWAY ALK2 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 36.1 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
1.2 16.8 REACTOME_COMMON_PATHWAY Genes involved in Common Pathway
1.1 10.1 REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
1.1 22.6 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
1.0 11.8 REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.9 2.8 REACTOME_BETA_DEFENSINS Genes involved in Beta defensins
0.7 33.2 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.7 9.8 REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY Genes involved in Adenylate cyclase activating pathway
0.4 15.4 REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.4 6.8 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.4 17.4 REACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.4 4.6 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.4 16.2 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.3 4.6 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.3 9.9 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.3 6.9 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.3 0.3 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
0.3 13.9 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.3 5.3 REACTOME_INHIBITION_OF_THE_PROTEOLYTIC_ACTIVITY_OF_APC_C_REQUIRED_FOR_THE_ONSET_OF_ANAPHASE_BY_MITOTIC_SPINDLE_CHECKPOINT_COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.3 3.3 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.3 3.8 REACTOME_REGULATION_OF_IFNG_SIGNALING Genes involved in Regulation of IFNG signaling
0.2 5.7 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.2 10.6 REACTOME_G1_PHASE Genes involved in G1 Phase
0.2 7.7 REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.2 10.0 REACTOME_INHIBITION_OF_INSULIN_SECRETION_BY_ADRENALINE_NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.2 2.3 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.2 0.7 REACTOME_PLATELET_CALCIUM_HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.2 9.1 REACTOME_NITRIC_OXIDE_STIMULATES_GUANYLATE_CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.2 1.4 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.2 2.1 REACTOME_GRB2_SOS_PROVIDES_LINKAGE_TO_MAPK_SIGNALING_FOR_INTERGRINS_ Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.2 4.1 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.2 4.7 REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES Genes involved in Generation of second messenger molecules
0.2 8.3 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.2 4.5 REACTOME_AQUAPORIN_MEDIATED_TRANSPORT Genes involved in Aquaporin-mediated transport
0.2 3.9 REACTOME_DAG_AND_IP3_SIGNALING Genes involved in DAG and IP3 signaling
0.2 9.0 REACTOME_GLUCOSE_TRANSPORT Genes involved in Glucose transport
0.2 4.6 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.2 2.7 REACTOME_IL_RECEPTOR_SHC_SIGNALING Genes involved in Interleukin receptor SHC signaling
0.2 3.8 REACTOME_METABOLISM_OF_NON_CODING_RNA Genes involved in Metabolism of non-coding RNA
0.2 3.8 REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE Genes involved in GPVI-mediated activation cascade
0.1 2.4 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 1.0 REACTOME_DOWNSTREAM_TCR_SIGNALING Genes involved in Downstream TCR signaling
0.1 4.2 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 9.4 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 3.1 REACTOME_FANCONI_ANEMIA_PATHWAY Genes involved in Fanconi Anemia pathway
0.1 3.1 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.1 25.0 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.1 1.9 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
0.1 2.0 REACTOME_NOD1_2_SIGNALING_PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.1 2.5 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 5.7 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 3.9 REACTOME_TRIGLYCERIDE_BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.1 7.3 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 1.3 REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 15.3 REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS Genes involved in G alpha (q) signalling events
0.1 5.2 REACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.1 1.9 REACTOME_MEIOTIC_RECOMBINATION Genes involved in Meiotic Recombination
0.1 4.6 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.1 3.3 REACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.1 2.4 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 2.1 REACTOME_ANTIGEN_PROCESSING_CROSS_PRESENTATION Genes involved in Antigen processing-Cross presentation
0.1 3.9 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 4.0 REACTOME_IL1_SIGNALING Genes involved in Interleukin-1 signaling
0.1 1.5 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 2.2 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 1.8 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 1.2 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.1 0.7 REACTOME_P38MAPK_EVENTS Genes involved in p38MAPK events
0.1 2.9 REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 2.2 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 1.3 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.1 1.4 REACTOME_RNA_POL_III_CHAIN_ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.1 3.0 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 1.7 REACTOME_KINESINS Genes involved in Kinesins
0.1 0.7 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 0.7 REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.1 0.4 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 0.1 REACTOME_MRNA_CAPPING Genes involved in mRNA Capping
0.1 0.8 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 0.8 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 1.1 REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.1 0.7 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.1 0.9 REACTOME_RNA_POL_I_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 1.0 REACTOME_PYRUVATE_METABOLISM Genes involved in Pyruvate metabolism
0.0 0.9 REACTOME_EXTENSION_OF_TELOMERES Genes involved in Extension of Telomeres
0.0 4.0 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 1.0 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 2.2 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.7 REACTOME_RAS_ACTIVATION_UOPN_CA2_INFUX_THROUGH_NMDA_RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 3.0 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 1.0 REACTOME_MRNA_SPLICING_MINOR_PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.6 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.0 2.3 REACTOME_MRNA_SPLICING Genes involved in mRNA Splicing
0.0 1.8 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 1.4 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.5 REACTOME_HIGHLY_CALCIUM_PERMEABLE_POSTSYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 1.5 REACTOME_LIPID_DIGESTION_MOBILIZATION_AND_TRANSPORT Genes involved in Lipid digestion, mobilization, and transport
0.0 1.2 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 1.4 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 1.3 REACTOME_AMYLOIDS Genes involved in Amyloids
0.0 0.5 REACTOME_REGULATION_OF_HYPOXIA_INDUCIBLE_FACTOR_HIF_BY_OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 1.6 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 2.6 REACTOME_POTASSIUM_CHANNELS Genes involved in Potassium Channels
0.0 0.1 REACTOME_SIGNALING_BY_WNT Genes involved in Signaling by Wnt
0.0 0.4 REACTOME_ERK_MAPK_TARGETS Genes involved in ERK/MAPK targets
0.0 1.2 REACTOME_GLUCOSE_METABOLISM Genes involved in Glucose metabolism
0.0 0.8 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 2.2 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.4 REACTOME_METAL_ION_SLC_TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.5 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane