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GSE58827: Dynamics of the Mouse Liver

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Results for Rxra

Z-value: 0.91

Motif logo

Transcription factors associated with Rxra

Gene Symbol Gene ID Gene Info
ENSMUSG00000015846.8 retinoid X receptor alpha

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Rxramm10_v2_chr2_+_27677201_276772290.124.9e-01Click!

Activity profile of Rxra motif

Sorted Z-values of Rxra motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_78422217 9.76 ENSMUST00000001122.5
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr19_+_39287074 9.11 ENSMUST00000003137.8
cytochrome P450, family 2, subfamily c, polypeptide 29
chr6_-_85820965 6.40 ENSMUST00000032074.3
camello-like 5
chr4_+_63356152 5.33 ENSMUST00000006687.4
orosomucoid 3
chr9_-_46235631 5.02 ENSMUST00000118649.1
apolipoprotein C-III
chr3_+_138415484 3.87 ENSMUST00000161312.1
ENSMUST00000013458.8
alcohol dehydrogenase 4 (class II), pi polypeptide
chr19_+_36554661 3.29 ENSMUST00000169036.2
ENSMUST00000047247.5
HECT domain containing 2
chr11_-_116199040 2.95 ENSMUST00000066587.5
acyl-Coenzyme A oxidase 1, palmitoyl
chr6_+_72636244 2.94 ENSMUST00000101278.2
predicted gene 15401
chr2_-_3419019 2.84 ENSMUST00000115084.1
ENSMUST00000115083.1
meiosis expressed gene 1
chr1_-_180245927 2.74 ENSMUST00000010753.7
presenilin 2
chr3_+_138374121 2.68 ENSMUST00000171054.1
alcohol dehydrogenase 6 (class V), pseudogene 1
chr2_-_3419066 2.58 ENSMUST00000115082.3
meiosis expressed gene 1
chr15_-_82380179 2.34 ENSMUST00000023083.7
cytochrome P450, family 2, subfamily d, polypeptide 22
chr6_-_85820936 2.33 ENSMUST00000174143.1
predicted gene 11128
chr18_+_12599894 2.31 ENSMUST00000169401.1
tetratricopeptide repeat domain 39C
chr1_-_180245757 2.13 ENSMUST00000111104.1
presenilin 2
chr11_-_116198701 2.05 ENSMUST00000072948.4
acyl-Coenzyme A oxidase 1, palmitoyl
chr6_-_129237948 1.92 ENSMUST00000181238.1
ENSMUST00000180379.1
RIKEN cDNA 2310001H17 gene
chr9_-_103288224 1.77 ENSMUST00000123530.1
RIKEN cDNA 1300017J02 gene
chr5_+_92571544 1.75 ENSMUST00000082382.7
family with sequence similarity 47, member E
chr12_-_79192248 1.74 ENSMUST00000161204.1
retinol dehydrogenase 11
chr16_+_81200697 1.74 ENSMUST00000067602.3
ENSMUST00000037785.7
neural cell adhesion molecule 2
chr1_+_74284930 1.70 ENSMUST00000113805.1
ENSMUST00000027370.6
ENSMUST00000087226.4
paroxysmal nonkinesiogenic dyskinesia
chr8_-_41133697 1.68 ENSMUST00000155055.1
ENSMUST00000059115.6
ENSMUST00000145860.1
mitochondrial tumor suppressor 1
chr19_+_5878622 1.68 ENSMUST00000136833.1
ENSMUST00000141362.1
solute carrier family 25, member 45
chr4_+_118429701 1.63 ENSMUST00000067896.3
elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1
chr17_-_73950172 1.63 ENSMUST00000024866.4
xanthine dehydrogenase
chr5_+_92571477 1.63 ENSMUST00000176621.1
ENSMUST00000175974.1
ENSMUST00000131166.2
ENSMUST00000176448.1
family with sequence similarity 47, member E
chr5_+_146079254 1.58 ENSMUST00000035571.8
cytochrome P450, family 3, subfamily a, polypeptide 59
chr9_-_103288290 1.58 ENSMUST00000035163.3
RIKEN cDNA 1300017J02 gene
chr7_-_90129339 1.56 ENSMUST00000181189.1
RIKEN cDNA 2310010J17 gene
chr11_+_9048575 1.39 ENSMUST00000043285.4
predicted gene 11992
chr13_-_23914998 1.34 ENSMUST00000021769.8
ENSMUST00000110407.2
solute carrier family 17 (sodium phosphate), member 4
chr1_-_169969143 1.33 ENSMUST00000027989.6
ENSMUST00000111353.3
hydroxysteroid (17-beta) dehydrogenase 7
chr4_-_103215147 1.33 ENSMUST00000150285.1
solute carrier family 35 (UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter), member D1
chr12_-_103830373 1.31 ENSMUST00000164454.2
serine (or cysteine) preptidase inhibitor, clade A, member 1B
chr19_-_44029201 1.31 ENSMUST00000026211.8
cytochrome P450, family 2, subfamily c, polypeptide 44
chr3_+_100825452 1.21 ENSMUST00000054791.7
V-set domain containing T cell activation inhibitor 1
chr7_+_30169861 1.12 ENSMUST00000085668.4
predicted gene 5113
chr19_-_6921804 1.11 ENSMUST00000025906.4
estrogen related receptor, alpha
chr9_-_22135675 1.09 ENSMUST00000165735.1
acid phosphatase 5, tartrate resistant
chr10_-_75822521 1.08 ENSMUST00000160211.1
glutathione S-transferase, theta 4
chr4_+_85205417 1.05 ENSMUST00000030212.8
ENSMUST00000107189.1
ENSMUST00000107184.1
SH3-domain GRB2-like 2
chr19_-_21472552 1.01 ENSMUST00000087600.3
guanine deaminase
chr3_+_88206786 0.99 ENSMUST00000181134.1
ENSMUST00000181550.1
predicted gene 3764
chr2_+_155381808 0.98 ENSMUST00000043237.7
ENSMUST00000174685.1
transformation related protein 53 inducible nuclear protein 2
chr17_-_35909626 0.94 ENSMUST00000141132.1
alpha tubulin acetyltransferase 1
chr19_-_6921753 0.93 ENSMUST00000173635.1
estrogen related receptor, alpha
chr17_-_15564322 0.89 ENSMUST00000147532.1
PR domain containing 9
chr6_-_124813065 0.89 ENSMUST00000149610.2
triosephosphate isomerase 1
chr12_-_74316394 0.87 ENSMUST00000110441.1
predicted gene 11042
chr4_+_137862237 0.86 ENSMUST00000102518.3
endothelin converting enzyme 1
chr10_+_112172540 0.84 ENSMUST00000132994.1
calcyphosphine 2
chr13_+_4574075 0.83 ENSMUST00000021628.3
aldo-keto reductase family 1, member C21
chr11_+_68968107 0.83 ENSMUST00000102606.3
ENSMUST00000018884.5
solute carrier family 25, member 35
chr16_+_5007283 0.82 ENSMUST00000184439.1
small integral membrane protein 22
chr15_-_76232045 0.81 ENSMUST00000167754.1
plectin
chr10_+_23960494 0.81 ENSMUST00000092660.1
trace amine-associated receptor 4
chr11_-_96747405 0.80 ENSMUST00000180492.1
RIKEN cDNA 2010300F17 gene
chr11_-_84870712 0.79 ENSMUST00000170741.1
ENSMUST00000172405.1
ENSMUST00000100686.3
ENSMUST00000108081.2
gametogenetin binding protein 2
chr9_-_122862128 0.79 ENSMUST00000056467.7
zinc finger protein 445
chr2_+_126215100 0.79 ENSMUST00000164042.2
predicted gene, 17555
chr6_+_8259327 0.75 ENSMUST00000159378.1
predicted gene 16039
chr9_-_44965519 0.75 ENSMUST00000125642.1
ENSMUST00000117506.1
ENSMUST00000117549.1
ubiquitination factor E4A, UFD2 homolog (S. cerevisiae)
chr11_-_11627824 0.74 ENSMUST00000081896.4
RIKEN cDNA 4930512M02 gene
chr2_+_164316730 0.74 ENSMUST00000017144.2
seminal vesicle secretory protein 6
chr7_+_44188205 0.74 ENSMUST00000073713.6
kallikrein 1-related peptidase b24
chr3_-_115888086 0.72 ENSMUST00000067500.5
RIKEN cDNA A930005H10 gene
chr16_+_29210108 0.70 ENSMUST00000162747.1
HRAS-like suppressor
chr6_+_71282280 0.70 ENSMUST00000080949.7
lysine-rich coiled-coil 1
chr10_+_77582387 0.68 ENSMUST00000162943.1
pituitary tumor-transforming 1 interacting protein
chr4_+_21879662 0.68 ENSMUST00000029909.2
coenzyme Q3 homolog, methyltransferase (yeast)
chr10_-_79984227 0.67 ENSMUST00000052885.7
transmembrane protein 259
chr7_-_30232186 0.67 ENSMUST00000006254.5
tubulin folding cofactor B
chr4_-_41640322 0.67 ENSMUST00000127306.1
energy homeostasis associated
chr3_-_151837451 0.66 ENSMUST00000029670.5
prostaglandin F receptor
chr9_-_121857952 0.65 ENSMUST00000060251.6
HIG1 domain family, member 1A
chr17_-_27820534 0.65 ENSMUST00000075076.4
ENSMUST00000114863.2
DNA segment, Chr 17, Wayne State University 92, expressed
chr1_-_172258410 0.62 ENSMUST00000111243.1
ATPase, Na+/K+ transporting, alpha 4 polypeptide
chr13_+_112927642 0.62 ENSMUST00000038574.5
DEAH (Asp-Glu-Ala-His) box polypeptide 29
chr16_+_15317458 0.62 ENSMUST00000178312.1
predicted gene, 21897
chr17_-_27820445 0.62 ENSMUST00000114859.1
DNA segment, Chr 17, Wayne State University 92, expressed
chr17_-_56717681 0.60 ENSMUST00000164907.1
vimentin-type intermediate filament associated coiled-coil protein
chr6_-_90224438 0.59 ENSMUST00000076086.2
vomeronasal 1 receptor 53
chr19_-_3912711 0.59 ENSMUST00000075092.6
NADH dehydrogenase (ubiquinone) Fe-S protein 8
chr2_-_164804876 0.58 ENSMUST00000103094.4
ENSMUST00000017451.6
acyl-CoA thioesterase 8
chr12_+_57564111 0.58 ENSMUST00000101398.3
tetratricopeptide repeat domain 6
chr16_+_5007306 0.57 ENSMUST00000178155.2
ENSMUST00000184256.1
ENSMUST00000185147.1
small integral membrane protein 22
chr9_+_40187079 0.56 ENSMUST00000062229.5
olfactory receptor 986
chr9_+_44772909 0.56 ENSMUST00000002099.3
intraflagellar transport 46
chr6_+_58640536 0.55 ENSMUST00000145161.1
ENSMUST00000114294.1
ATP-binding cassette, sub-family G (WHITE), member 2
chr15_-_76232554 0.55 ENSMUST00000166428.1
plectin
chr11_-_84870812 0.55 ENSMUST00000168434.1
gametogenetin binding protein 2
chr10_-_79983970 0.55 ENSMUST00000124536.1
transmembrane protein 259
chr2_+_164332740 0.55 ENSMUST00000017148.7
seminal vesicle secretory protein 5
chr3_+_27317028 0.54 ENSMUST00000046383.5
ENSMUST00000174840.1
tumor necrosis factor (ligand) superfamily, member 10
chr5_-_72974702 0.54 ENSMUST00000043711.8
predicted gene 10135
chr1_-_132707304 0.54 ENSMUST00000043189.7
neurofascin
chr9_-_21073494 0.54 ENSMUST00000010348.5
ferredoxin 1-like
chr11_+_120677226 0.53 ENSMUST00000129644.2
ENSMUST00000151160.1
alveolar soft part sarcoma chromosome region, candidate 1 (human)
chr2_+_147187424 0.52 ENSMUST00000144411.1
RIKEN cDNA 6430503K07 gene
chr9_-_48964990 0.52 ENSMUST00000008734.4
5-hydroxytryptamine (serotonin) receptor 3B
chr11_+_120442644 0.51 ENSMUST00000044105.8
tetraspanin 10
chr9_-_110989611 0.50 ENSMUST00000084922.5
receptor transporter protein 3
chr11_+_97798995 0.50 ENSMUST00000143571.1
LIM and SH3 protein 1
chr5_-_129887442 0.49 ENSMUST00000094280.3
coiled-coil-helix-coiled-coil-helix domain containing 2
chr11_-_53423123 0.49 ENSMUST00000036045.5
liver-expressed antimicrobial peptide 2
chr1_+_171331414 0.49 ENSMUST00000097467.1
death effector domain-containing
chr7_-_18532225 0.48 ENSMUST00000094795.4
pregnancy-specific glycoprotein 25
chr2_+_59160838 0.48 ENSMUST00000102754.4
ENSMUST00000168631.1
ENSMUST00000123908.1
plakophilin 4
chr9_+_44772951 0.47 ENSMUST00000128150.1
intraflagellar transport 46
chr14_+_53665912 0.47 ENSMUST00000181768.1
T cell receptor alpha variable 3-3
chr1_-_63176653 0.46 ENSMUST00000027111.8
ENSMUST00000168099.2
NADH dehydrogenase (ubiquinone) Fe-S protein 1
chr1_-_57406443 0.46 ENSMUST00000160837.1
ENSMUST00000161780.1
tRNA-yW synthesizing protein 5
chr9_-_109626059 0.44 ENSMUST00000073962.6
F-box and WD-40 domain protein 24
chr11_-_106272927 0.44 ENSMUST00000021052.9
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
chr17_+_56717759 0.43 ENSMUST00000002452.6
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 11
chr4_+_118409331 0.41 ENSMUST00000084319.4
ENSMUST00000106384.3
ENSMUST00000126089.1
ENSMUST00000073881.1
ENSMUST00000019229.8
ENSMUST00000144577.1
mediator of RNA polymerase II transcription, subunit 8 homolog (yeast)
chr9_+_44773027 0.41 ENSMUST00000125877.1
intraflagellar transport 46
chr4_-_133633419 0.40 ENSMUST00000084238.4
zinc finger, DHHC domain containing 18
chr17_-_35910032 0.40 ENSMUST00000141662.1
ENSMUST00000056034.6
ENSMUST00000077494.6
ENSMUST00000149277.1
ENSMUST00000061052.5
alpha tubulin acetyltransferase 1
chr8_-_99416397 0.39 ENSMUST00000155527.1
ENSMUST00000142129.1
ENSMUST00000093249.4
ENSMUST00000142475.2
ENSMUST00000128860.1
cadherin 8
chr12_-_98901478 0.38 ENSMUST00000065716.6
echinoderm microtubule associated protein like 5
chr4_+_45799016 0.38 ENSMUST00000044384.4
aldehyde dehydrogenase 1 family, member B1
chr4_-_137574569 0.38 ENSMUST00000178923.1
low density lipoprotein receptor A domain containing 2
chr12_-_93929102 0.37 ENSMUST00000180321.1
predicted gene 9726
chr3_+_115888139 0.37 ENSMUST00000106505.1
ENSMUST00000043342.9
DPH5 homolog (S. cerevisiae)
chr9_+_44773191 0.37 ENSMUST00000147559.1
intraflagellar transport 46
chr11_-_53618659 0.37 ENSMUST00000000889.6
interleukin 4
chr8_-_85014408 0.36 ENSMUST00000059072.4
bestrophin 2
chr18_-_80200597 0.36 ENSMUST00000025462.6
ribosome binding factor A
chr14_+_53776930 0.36 ENSMUST00000103670.2
T cell receptor alpha variable 3-4
chr7_-_18616498 0.36 ENSMUST00000057810.6
pregnancy-specific glycoprotein 23
chr10_+_63061582 0.35 ENSMUST00000020266.8
ENSMUST00000178684.1
phenazine biosynthesis-like protein domain containing 1
chr10_+_77581720 0.35 ENSMUST00000009435.5
pituitary tumor-transforming 1 interacting protein
chr7_-_30169701 0.34 ENSMUST00000062181.7
zinc finger protein 146
chr10_+_24049482 0.34 ENSMUST00000071691.2
trace amine-associated receptor 7F
chr13_+_33484784 0.34 ENSMUST00000081927.2
serine (or cysteine) peptidase inhibitor, clade B, member 9g
chr7_+_132859225 0.33 ENSMUST00000084497.5
ENSMUST00000181577.1
ENSMUST00000106161.1
family with sequence similarity 175, member B
chr16_-_4624984 0.32 ENSMUST00000014445.6
presequence translocase-asssociated motor 16 homolog (S. cerevisiae)
chr2_-_129699833 0.32 ENSMUST00000028883.5
prodynorphin
chr18_+_63708689 0.31 ENSMUST00000072726.5
WD repeat domain 7
chr8_+_83566671 0.31 ENSMUST00000036996.5
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7
chr4_-_118409219 0.31 ENSMUST00000075406.5
seizure threshold 2
chr10_+_77581774 0.31 ENSMUST00000162429.1
pituitary tumor-transforming 1 interacting protein
chr16_-_44139196 0.30 ENSMUST00000063661.6
ENSMUST00000114666.2
ATPase, H+ transporting, lysosomal V1 subunit A
chr6_+_90269106 0.30 ENSMUST00000058039.2
vomeronasal 1 receptor 54
chr9_+_46228580 0.30 ENSMUST00000034588.8
apolipoprotein A-I
chr10_-_82622926 0.29 ENSMUST00000176200.1
ENSMUST00000183416.1
RIKEN cDNA 1190007I07 gene
chr9_-_109495875 0.29 ENSMUST00000076617.4
F-box and WD-40 domain protein 19
chr12_+_107488632 0.28 ENSMUST00000082269.2
RIKEN cDNA 3110018I06 gene
chr7_-_18354944 0.28 ENSMUST00000098783.4
ENSMUST00000003597.8
pregnancy specific glycoprotein 18
chr9_+_21002737 0.26 ENSMUST00000003386.5
mitochondrial ribosomal protein L4
chr14_+_73661225 0.26 ENSMUST00000098874.3
predicted gene, 21750
chr10_-_82623190 0.26 ENSMUST00000183363.1
ENSMUST00000079648.5
ENSMUST00000185168.1
RIKEN cDNA 1190007I07 gene
chr4_-_144274027 0.26 ENSMUST00000105752.3
preferentially expressed antigen in melanoma like 5
chr14_+_31208309 0.25 ENSMUST00000169169.1
troponin C, cardiac/slow skeletal
chr11_-_96747419 0.25 ENSMUST00000181758.1
RIKEN cDNA 2010300F17 gene
chr11_+_51027004 0.24 ENSMUST00000072152.1
olfactory receptor 54
chr7_-_30559828 0.23 ENSMUST00000108164.1
lin-37 homolog (C. elegans)
chr8_-_72492592 0.23 ENSMUST00000152080.1
solute carrier family 35, member E1
chr7_-_44257204 0.22 ENSMUST00000012921.7
acid phosphatase, testicular
chr2_-_69342600 0.22 ENSMUST00000102709.1
ENSMUST00000102710.3
ENSMUST00000180142.1
ATP-binding cassette, sub-family B (MDR/TAP), member 11
chr9_+_108392820 0.21 ENSMUST00000035234.4
RIKEN cDNA 1700102P08 gene
chr17_-_24650270 0.20 ENSMUST00000002572.4
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
chr15_+_80948484 0.20 ENSMUST00000023043.2
ENSMUST00000168756.1
ENSMUST00000164806.1
adenylosuccinate lyase
chr12_+_83763628 0.20 ENSMUST00000121733.1
papilin, proteoglycan-like sulfated glycoprotein
chrX_-_148615153 0.19 ENSMUST00000112755.2
predicted gene 8334
chr16_-_97962581 0.19 ENSMUST00000113734.2
ENSMUST00000052089.7
ENSMUST00000063605.7
zinc finger and BTB domain containing 21
chr8_-_116921365 0.19 ENSMUST00000128304.1
COX assembly mitochondrial protein 2
chr12_+_55155104 0.18 ENSMUST00000110708.2
signal recognition particle 54B
chr11_-_70015346 0.18 ENSMUST00000018718.7
ENSMUST00000102574.3
acyl-Coenzyme A dehydrogenase, very long chain
chr8_-_4217459 0.17 ENSMUST00000176227.1
cDNA sequence BC068157
chr15_-_89123087 0.17 ENSMUST00000109353.2
tubulin, gamma complex associated protein 6
chr8_-_22060019 0.17 ENSMUST00000110738.2
ATPase, Cu++ transporting, beta polypeptide
chr7_+_106814135 0.16 ENSMUST00000075414.1
ENSMUST00000166880.1
olfactory receptor 701
chr7_+_43444104 0.16 ENSMUST00000004729.3
electron transferring flavoprotein, beta polypeptide
chr12_-_33092875 0.15 ENSMUST00000095774.2
cadherin-related family member 3
chr13_+_13590402 0.15 ENSMUST00000110559.1
lysosomal trafficking regulator
chr18_+_4375583 0.15 ENSMUST00000025077.6
mitochondrial poly(A) polymerase
chr11_+_85311232 0.15 ENSMUST00000020835.9
protein phosphatase 1D magnesium-dependent, delta isoform
chr3_-_92687209 0.14 ENSMUST00000029524.3
late cornified envelope 1D
chr14_+_56017964 0.14 ENSMUST00000022836.4
mast cell protease 1
chr7_-_18484149 0.14 ENSMUST00000094798.3
pregnancy-specific glycoprotein 26
chr4_+_134068429 0.14 ENSMUST00000121391.1
absent in melanoma 1-like
chr2_+_23207470 0.14 ENSMUST00000028113.3
ENSMUST00000114505.1
RIKEN cDNA 4931423N10 gene
chr11_-_118093702 0.13 ENSMUST00000018719.3
dynein, axonemal, heavy chain 17
chr11_+_98383811 0.12 ENSMUST00000008021.2
titin-cap
chr16_+_44139821 0.12 ENSMUST00000159514.1
ENSMUST00000161326.1
ENSMUST00000063520.8
ENSMUST00000063542.7
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr13_+_43370710 0.12 ENSMUST00000066804.4
sirtuin 5
chr15_+_89532816 0.12 ENSMUST00000167173.1
SH3/ankyrin domain gene 3
chr19_-_43912392 0.12 ENSMUST00000026209.4
dynamin binding protein
chr11_+_4620067 0.11 ENSMUST00000109941.1
predicted gene 11032
chr2_-_119229849 0.10 ENSMUST00000110820.2
protein phosphatase 1, regulatory (inhibitor) subunit 14D
chr15_-_77447444 0.10 ENSMUST00000089469.5
apolipoprotein L 7b
chr9_-_109746089 0.10 ENSMUST00000071917.3
F-box and WD-40 domain protein 26
chr9_-_109287651 0.10 ENSMUST00000119470.1
ENSMUST00000112041.2
ENSMUST00000066901.4
F-box and WD-40 domain protein 14
chr4_+_85205120 0.10 ENSMUST00000107188.3
SH3-domain GRB2-like 2
chr2_-_164200076 0.09 ENSMUST00000063251.2
WAP four-disulfide core domain 15A

Network of associatons between targets according to the STRING database.

First level regulatory network of Rxra

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 5.0 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
1.0 3.9 GO:0006069 ethanol oxidation(GO:0006069)
0.8 5.0 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.4 1.3 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.4 1.7 GO:0036367 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.4 2.6 GO:0006145 purine nucleobase catabolic process(GO:0006145)
0.3 4.9 GO:0043589 Notch receptor processing(GO:0007220) skin morphogenesis(GO:0043589)
0.3 10.4 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.3 0.9 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.3 0.9 GO:0019405 alditol catabolic process(GO:0019405) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.3 0.9 GO:0034959 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.3 1.3 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.3 2.3 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.2 0.6 GO:0019389 glucuronoside metabolic process(GO:0019389)
0.2 1.1 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.2 1.7 GO:0061727 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.2 0.7 GO:0071798 response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.2 1.1 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.2 0.5 GO:0031590 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.1 1.6 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 1.2 GO:0072602 interleukin-4 secretion(GO:0072602) positive regulation of interleukin-2 secretion(GO:1900042)
0.1 1.3 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 0.4 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.1 0.3 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.1 0.5 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.1 1.4 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.4 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 0.2 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.1 1.3 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.1 0.3 GO:0010901 regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
0.1 1.2 GO:1904294 positive regulation of ERAD pathway(GO:1904294)
0.1 1.8 GO:0060285 cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285)
0.1 0.2 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.1 0.2 GO:0015680 intracellular copper ion transport(GO:0015680)
0.1 0.2 GO:0046618 drug export(GO:0046618)
0.1 0.3 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.0 2.0 GO:1900078 positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0 1.7 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.0 8.4 GO:0098656 anion transmembrane transport(GO:0098656)
0.0 0.6 GO:0043649 dicarboxylic acid catabolic process(GO:0043649)
0.0 0.7 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.8 GO:0010566 regulation of ketone biosynthetic process(GO:0010566)
0.0 1.3 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.2 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.0 0.8 GO:0007635 chemosensory behavior(GO:0007635)
0.0 0.4 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.7 GO:0090201 negative regulation of release of cytochrome c from mitochondria(GO:0090201)
0.0 0.9 GO:0019236 response to pheromone(GO:0019236)
0.0 1.3 GO:0006953 acute-phase response(GO:0006953)
0.0 0.5 GO:1900037 regulation of cellular response to hypoxia(GO:1900037)
0.0 0.2 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.5 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.1 GO:1904717 regulation of AMPA glutamate receptor clustering(GO:1904717)
0.0 0.1 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.0 0.2 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.0 0.1 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.0 0.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.3 GO:2001179 regulation of interleukin-10 secretion(GO:2001179)
0.0 0.7 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.1 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.0 5.2 GO:0051321 meiotic cell cycle(GO:0051321)
0.0 0.5 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 0.3 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.0 0.1 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.0 1.1 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.5 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.2 GO:0045838 positive regulation of membrane potential(GO:0045838)
0.0 1.3 GO:0035725 sodium ion transmembrane transport(GO:0035725)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 5.3 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.2 4.9 GO:0035253 ciliary rootlet(GO:0035253)
0.1 1.3 GO:0097427 microtubule bundle(GO:0097427)
0.1 0.5 GO:0097454 Schwann cell microvillus(GO:0097454)
0.1 1.7 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 0.3 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.1 0.6 GO:0045098 type III intermediate filament(GO:0045098)
0.1 0.9 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 1.4 GO:0030056 hemidesmosome(GO:0030056)
0.1 0.3 GO:1990130 Iml1 complex(GO:1990130)
0.1 1.8 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 4.5 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.7 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.2 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0 0.2 GO:1990584 cardiac Troponin complex(GO:1990584)
0.0 1.8 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.3 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.3 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.4 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.6 GO:0044438 microbody part(GO:0044438) peroxisomal part(GO:0044439)
0.0 0.2 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.4 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 1.6 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 0.0 GO:0055087 Ski complex(GO:0055087)
0.0 0.5 GO:0051233 desmosome(GO:0030057) spindle midzone(GO:0051233)
0.0 0.1 GO:0031415 NatA complex(GO:0031415)
0.0 0.8 GO:0005776 autophagosome(GO:0005776)
0.0 1.6 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 9.1 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
1.3 5.3 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
1.3 3.9 GO:0003960 NADPH:quinone reductase activity(GO:0003960) alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.8 5.0 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.6 4.9 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.5 1.6 GO:0008390 testosterone 16-alpha-hydroxylase activity(GO:0008390)
0.4 1.3 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.3 1.6 GO:0016726 xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726)
0.3 1.7 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.3 0.8 GO:0070401 NADP+ binding(GO:0070401) lithocholic acid binding(GO:1902121)
0.2 1.3 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.2 1.7 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.2 0.5 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.2 0.7 GO:0008169 C-methyltransferase activity(GO:0008169)
0.1 1.3 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1 1.6 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.4 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.1 1.2 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 1.1 GO:0003993 acid phosphatase activity(GO:0003993)
0.1 3.6 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391)
0.1 1.3 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.1 0.9 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 0.6 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.1 0.8 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 0.2 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466) very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.1 0.5 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 0.6 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 0.7 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 0.6 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 0.7 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.0 0.2 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 9.8 GO:0015293 symporter activity(GO:0015293)
0.0 1.4 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.3 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.2 GO:0043682 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
0.0 0.9 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 1.4 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.6 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.2 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.2 GO:0031013 troponin I binding(GO:0031013)
0.0 0.9 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 0.1 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.0 0.1 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.6 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.1 GO:0051373 FATZ binding(GO:0051373)
0.0 1.1 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 2.0 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 2.3 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 1.8 GO:0002039 p53 binding(GO:0002039)
0.0 0.4 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.2 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.2 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 1.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.4 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 3.1 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.3 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.4 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.9 PID LKB1 PATHWAY LKB1 signaling events
0.0 1.1 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.5 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.6 PID HIF2PATHWAY HIF-2-alpha transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 9.8 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.6 3.9 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.3 4.9 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.3 5.6 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.3 5.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.2 2.6 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 1.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 0.6 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 1.6 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 0.7 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.1 1.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 1.1 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.5 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 1.4 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.7 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 2.0 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.9 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 1.3 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.5 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.2 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 1.1 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.8 REACTOME ION CHANNEL TRANSPORT Genes involved in Ion channel transport
0.0 0.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.9 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling