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GSE58827: Dynamics of the Mouse Liver

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Results for Sox18_Sox12

Z-value: 1.65

Motif logo

Transcription factors associated with Sox18_Sox12

Gene Symbol Gene ID Gene Info
ENSMUSG00000046470.5 SRY (sex determining region Y)-box 18
ENSMUSG00000051817.8 SRY (sex determining region Y)-box 12

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Sox12mm10_v2_chr2_-_152398046_152398076-0.861.8e-11Click!
Sox18mm10_v2_chr2_-_181671622_181671645-0.511.5e-03Click!

Activity profile of Sox18_Sox12 motif

Sorted Z-values of Sox18_Sox12 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_40089688 21.90 ENSMUST00000068094.6
ENSMUST00000080171.2
cytochrome P450, family 2, subfamily c, polypeptide 50
chr19_-_7802578 20.14 ENSMUST00000120522.1
ENSMUST00000065634.7
solute carrier family 22 (organic cation transporter), member 26
chr18_-_74961252 16.69 ENSMUST00000066532.4
lipase, endothelial
chr3_+_63295815 14.82 ENSMUST00000029400.1
membrane metallo endopeptidase
chr19_-_7966000 13.66 ENSMUST00000182102.1
ENSMUST00000075619.4
solute carrier family 22, member 27
chr2_+_102706356 10.77 ENSMUST00000123759.1
ENSMUST00000111212.1
ENSMUST00000005220.4
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr19_-_8405060 9.47 ENSMUST00000064507.5
ENSMUST00000120540.1
ENSMUST00000096269.4
solute carrier family 22, member 30
chr2_+_102659213 9.15 ENSMUST00000111213.1
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr13_+_4049001 8.99 ENSMUST00000118717.2
aldo-keto reductase family 1, member C14
chr1_-_72212249 8.92 ENSMUST00000048860.7
melanoregulin
chr19_-_8218832 8.92 ENSMUST00000113298.2
solute carrier family 22. member 29
chr9_+_74976096 8.87 ENSMUST00000081746.5
family with sequence similarity 214, member A
chr5_-_87337165 8.51 ENSMUST00000031195.2
UDP glucuronosyltransferase 2 family, polypeptide A3
chr3_-_113577743 8.05 ENSMUST00000067980.5
amylase 1, salivary
chr1_+_88087802 7.88 ENSMUST00000113139.1
UDP glucuronosyltransferase 1 family, polypeptide A8
chr7_+_100009914 7.14 ENSMUST00000107084.1
chordin-like 2
chr7_+_127800604 7.04 ENSMUST00000046863.5
ENSMUST00000106272.1
ENSMUST00000139068.1
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr4_+_134396320 7.02 ENSMUST00000105869.2
platelet-activating factor acetylhydrolase 2
chr13_-_55426769 6.90 ENSMUST00000170921.1
coagulation factor XII (Hageman factor)
chr5_-_86926521 6.58 ENSMUST00000031183.2
UDP glucuronosyltransferase 2 family, polypeptide B1
chr16_+_56204313 6.41 ENSMUST00000160116.1
ENSMUST00000069936.7
interphotoreceptor matrix proteoglycan 2
chr19_-_8131982 6.29 ENSMUST00000065651.4
solute carrier family 22, member 28
chr1_-_130661613 5.92 ENSMUST00000027657.7
complement component 4 binding protein
chr6_-_141946960 5.75 ENSMUST00000042119.5
solute carrier organic anion transporter family, member 1a1
chr4_+_60003438 5.73 ENSMUST00000107517.1
ENSMUST00000107520.1
major urinary protein 6
chr1_-_130661584 5.37 ENSMUST00000137276.2
complement component 4 binding protein
chr8_-_93337195 5.36 ENSMUST00000044602.7
carboxylesterase 1G
chr12_+_40446050 5.25 ENSMUST00000037488.6
dedicator of cytokinesis 4
chr17_+_12584183 5.23 ENSMUST00000046959.7
solute carrier family 22 (organic cation transporter), member 2
chr6_-_141946791 5.18 ENSMUST00000168119.1
solute carrier organic anion transporter family, member 1a1
chr1_-_139781236 4.91 ENSMUST00000027612.8
ENSMUST00000111989.2
ENSMUST00000111986.2
predicted gene 4788
chr1_-_140183404 4.44 ENSMUST00000066859.6
ENSMUST00000111976.2
complement component factor h
chr1_-_140183283 4.29 ENSMUST00000111977.1
complement component factor h
chr19_+_4711153 4.27 ENSMUST00000008991.6
spectrin beta, non-erythrocytic 2
chr10_+_62071014 4.22 ENSMUST00000053865.5
predicted gene 5424
chr16_-_23520579 4.12 ENSMUST00000089883.5
mannan-binding lectin serine peptidase 1
chr13_-_19307551 4.05 ENSMUST00000103561.1
T-cell receptor gamma, constant 2
chr1_-_169747634 4.00 ENSMUST00000027991.5
ENSMUST00000111357.1
regulator of G-protein signaling 4
chr8_-_93229517 3.92 ENSMUST00000176282.1
ENSMUST00000034173.7
carboxylesterase 1E
chr11_+_101367542 3.91 ENSMUST00000019469.2
glucose-6-phosphatase, catalytic
chrX_+_100767719 3.87 ENSMUST00000000901.6
ENSMUST00000113736.2
ENSMUST00000087984.4
discs, large homolog 3 (Drosophila)
chr13_-_55426783 3.82 ENSMUST00000021948.8
coagulation factor XII (Hageman factor)
chr8_-_109579056 3.81 ENSMUST00000074898.6
haptoglobin
chr7_+_19228334 3.71 ENSMUST00000063976.8
optic atrophy 3
chr17_-_59013264 3.68 ENSMUST00000174122.1
ENSMUST00000025065.5
nudix (nucleoside diphosphate linked moiety X)-type motif 12
chr2_+_176236860 3.67 ENSMUST00000166464.1
RIKEN cDNA 2210418O10 gene
chr1_-_133921393 3.65 ENSMUST00000048432.5
proline arginine-rich end leucine-rich repeat
chrX_+_140907602 3.62 ENSMUST00000033806.4
V-set and immunoglobulin domain containing 1
chr6_+_122308684 3.61 ENSMUST00000007602.8
ENSMUST00000112610.1
mannose-6-phosphate receptor, cation dependent
chr19_-_34527396 3.57 ENSMUST00000049572.8
ENSMUST00000178114.1
lysosomal acid lipase A
chr1_+_67123015 3.48 ENSMUST00000027144.7
carbamoyl-phosphate synthetase 1
chr6_-_98342728 3.44 ENSMUST00000164491.1
predicted gene 765
chr16_-_91618986 3.42 ENSMUST00000143058.1
ENSMUST00000049244.8
ENSMUST00000169982.1
ENSMUST00000133731.1
DnaJ (Hsp40) homolog, subfamily C, member 28
chr5_-_87591582 3.41 ENSMUST00000031201.7
sulfotransferase family 1E, member 1
chr7_-_25539845 3.35 ENSMUST00000066503.7
ENSMUST00000064862.6
carcinoembryonic antigen-related cell adhesion molecule 2
chr1_+_88070765 3.31 ENSMUST00000073772.4
UDP glucuronosyltransferase 1 family, polypeptide A9
chr5_-_31108218 3.20 ENSMUST00000182776.1
ENSMUST00000182444.1
solute carrier family 30 (zinc transporter), member 3
chr2_-_86347764 3.18 ENSMUST00000099894.2
olfactory receptor 1055
chr11_-_69369377 3.14 ENSMUST00000092971.6
ENSMUST00000108661.1
chromodomain helicase DNA binding protein 3
chrX_+_142228177 3.10 ENSMUST00000112914.1
nuclear transport factor 2-like export factor 2
chr11_+_4873951 3.03 ENSMUST00000038570.2
4-nitrophenylphosphatase domain and non-neuronal SNAP25-like protein homolog 1 (C. elegans)
chr2_+_173153048 3.03 ENSMUST00000029017.5
phosphoenolpyruvate carboxykinase 1, cytosolic
chr1_+_44119952 3.02 ENSMUST00000114709.2
basic, immunoglobulin-like variable motif containing
chrX_+_139563316 2.98 ENSMUST00000113027.1
ring finger protein 128
chr10_+_107271827 2.91 ENSMUST00000020057.8
ENSMUST00000105280.3
lin-7 homolog A (C. elegans)
chr8_-_67910911 2.89 ENSMUST00000093468.5
pleckstrin and Sec7 domain containing 3
chr2_-_160859601 2.87 ENSMUST00000103112.1
zinc fingers and homeoboxes 3
chr13_-_4279420 2.86 ENSMUST00000021632.3
aldo-keto reductase family 1, member C12
chr2_+_122147680 2.84 ENSMUST00000102476.4
beta-2 microglobulin
chrM_+_9870 2.80 ENSMUST00000084013.1
mitochondrially encoded NADH dehydrogenase 4L
chr3_+_67430096 2.75 ENSMUST00000077271.6
ENSMUST00000161009.1
G elongation factor, mitochondrial 1
chrX_+_142227923 2.71 ENSMUST00000042329.5
nuclear transport factor 2-like export factor 2
chr5_-_105343929 2.65 ENSMUST00000183149.1
guanylate binding protein 11
chr10_-_92375367 2.65 ENSMUST00000182870.1
predicted gene, 20757
chr1_+_171214013 2.59 ENSMUST00000111328.1
nuclear receptor subfamily 1, group I, member 3
chr8_-_84773381 2.57 ENSMUST00000109764.1
nuclear factor I/X
chr3_-_113574758 2.56 ENSMUST00000106540.1
amylase 1, salivary
chrM_+_10167 2.56 ENSMUST00000082414.1
mitochondrially encoded NADH dehydrogenase 4
chr9_-_36797303 2.55 ENSMUST00000115086.5
etoposide induced 2.4 mRNA
chr7_+_24271568 2.54 ENSMUST00000032696.6
zinc finger protein 93
chr5_+_14514918 2.54 ENSMUST00000030691.10
ENSMUST00000182407.1
piccolo (presynaptic cytomatrix protein)
chr1_+_165788681 2.53 ENSMUST00000161971.1
ENSMUST00000178336.1
ENSMUST00000005907.5
ENSMUST00000027849.4
CD247 antigen
chr2_+_126552407 2.52 ENSMUST00000061491.7
solute carrier family 27 (fatty acid transporter), member 2
chr14_+_62837679 2.50 ENSMUST00000014691.8
WD repeat and FYVE domain containing 2
chr6_-_124741374 2.49 ENSMUST00000004389.5
gene rich cluster, C10 gene
chr3_-_113574242 2.45 ENSMUST00000142505.2
amylase 1, salivary
chr1_-_24612700 2.44 ENSMUST00000088336.1
predicted gene 10222
chr2_-_84775420 2.41 ENSMUST00000111641.1
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr9_+_8971791 2.41 ENSMUST00000104915.2
predicted gene 16485
chr13_+_4059565 2.38 ENSMUST00000041768.6
aldo-keto reductase family 1, member C14
chr1_-_59161594 2.33 ENSMUST00000078874.7
ENSMUST00000066374.7
membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)
chr8_-_45294854 2.32 ENSMUST00000116473.2
kallikrein B, plasma 1
chrX_-_70477170 2.31 ENSMUST00000101506.3
ENSMUST00000114630.2
cDNA sequence BC023829
chr15_+_31602106 2.30 ENSMUST00000042702.6
family with sequence similarity 173, member B
chr14_+_66140919 2.28 ENSMUST00000022620.9
cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal)
chr19_+_12674179 2.28 ENSMUST00000057924.2
olfactory receptor 1442
chr2_+_25653111 2.27 ENSMUST00000038482.6
lipocalin 8
chrX_+_20549780 2.25 ENSMUST00000023832.6
regucalcin
chr18_-_3281036 2.24 ENSMUST00000049942.6
ENSMUST00000139537.1
ENSMUST00000124747.1
cAMP responsive element modulator
chr6_-_142278836 2.22 ENSMUST00000111825.3
solute carrier organic anion transporter family, member 1a5
chr13_-_62888282 2.22 ENSMUST00000092888.4
fructose bisphosphatase 1
chr4_-_129239165 2.20 ENSMUST00000097873.3
expressed sequence C77080
chr5_-_88526496 2.19 ENSMUST00000164073.1
immunoglobulin joining chain
chr13_+_40859768 2.17 ENSMUST00000110191.2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr1_+_171213969 2.15 ENSMUST00000005820.4
ENSMUST00000075469.5
ENSMUST00000155126.1
nuclear receptor subfamily 1, group I, member 3
chr1_+_176814660 2.10 ENSMUST00000056773.8
ENSMUST00000027785.8
serologically defined colon cancer antigen 8
chr18_-_56572888 2.08 ENSMUST00000174518.1
aldehyde dehydrogenase family 7, member A1
chr16_-_37654408 2.07 ENSMUST00000023514.3
NADH dehydrogenase (ubiquinone) 1 beta subcomplex 4
chr1_+_160978576 2.06 ENSMUST00000064725.5
serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1
chr13_+_93674403 2.02 ENSMUST00000048001.6
dimethylglycine dehydrogenase precursor
chr9_+_7692086 1.96 ENSMUST00000018767.7
matrix metallopeptidase 7
chr4_-_70534904 1.96 ENSMUST00000107359.2
multiple EGF-like-domains 9
chr13_+_23839445 1.95 ENSMUST00000091698.4
ENSMUST00000110422.1
solute carrier family 17 (sodium phosphate), member 3
chr7_+_13398115 1.93 ENSMUST00000005791.7
calcium binding protein 5
chr14_-_34310503 1.91 ENSMUST00000111917.1
family with sequence similarity 35, member A
chr13_+_23839401 1.91 ENSMUST00000039721.7
ENSMUST00000166467.1
solute carrier family 17 (sodium phosphate), member 3
chr17_-_40242285 1.90 ENSMUST00000026499.5
cysteine-rich secretory protein 3
chr10_+_28668560 1.89 ENSMUST00000161345.1
thymocyte selection associated
chr10_+_34483400 1.87 ENSMUST00000019913.7
ENSMUST00000170771.1
fyn-related kinase
chr3_+_89459118 1.86 ENSMUST00000029564.5
phosphomevalonate kinase
chr2_-_67194695 1.85 ENSMUST00000147939.1
predicted gene 13598
chr12_-_76177251 1.84 ENSMUST00000101291.3
ENSMUST00000076634.4
estrogen receptor 2 (beta)
chr3_-_33082004 1.82 ENSMUST00000108225.3
peroxisomal biogenesis factor 5-like
chr9_+_52047150 1.77 ENSMUST00000163153.1
radixin
chrM_+_14138 1.76 ENSMUST00000082421.1
mitochondrially encoded cytochrome b
chr8_-_22694061 1.74 ENSMUST00000131767.1
inhibitor of kappaB kinase beta
chrM_+_9452 1.71 ENSMUST00000082411.1
mitochondrially encoded NADH dehydrogenase 3
chr6_-_128581597 1.69 ENSMUST00000060574.7
cDNA sequence BC048546
chr17_+_53566971 1.67 ENSMUST00000000724.8
K(lysine) acetyltransferase 2B
chr10_-_117238647 1.66 ENSMUST00000159193.1
RIKEN cDNA 9530003J23 gene
chr7_-_140882274 1.65 ENSMUST00000026559.7
sirtuin 3
chr16_-_3908639 1.63 ENSMUST00000115859.1
RIKEN cDNA 1700037C18 gene
chr4_-_15945359 1.63 ENSMUST00000029877.8
2,4-dienoyl CoA reductase 1, mitochondrial
chr4_+_145696161 1.61 ENSMUST00000180014.1
predicted gene 13242
chr2_+_158666690 1.60 ENSMUST00000103116.3
protein phosphatase 1, regulatory (inhibitor) subunit 16B
chr3_-_57692537 1.59 ENSMUST00000099091.3
predicted gene 410
chr9_-_36797273 1.58 ENSMUST00000163192.3
etoposide induced 2.4 mRNA
chr3_+_95893953 1.57 ENSMUST00000056710.8
ENSMUST00000015894.5
anterior pharynx defective 1a homolog (C. elegans)
chr14_-_11162008 1.56 ENSMUST00000162278.1
ENSMUST00000160340.1
ENSMUST00000160956.1
fragile histidine triad gene
chr18_+_60293372 1.55 ENSMUST00000171297.1
RIKEN cDNA F830016B08 gene
chr1_+_52845013 1.53 ENSMUST00000159352.1
ENSMUST00000044478.6
3-hydroxyisobutyryl-Coenzyme A hydrolase
chrM_-_14060 1.53 ENSMUST00000082419.1
mitochondrially encoded NADH dehydrogenase 6
chrM_+_2743 1.52 ENSMUST00000082392.1
mitochondrially encoded NADH dehydrogenase 1
chr5_+_92809372 1.50 ENSMUST00000113054.2
shroom family member 3
chr1_+_165788746 1.50 ENSMUST00000161559.2
CD247 antigen
chr1_-_155527083 1.48 ENSMUST00000097531.2
predicted gene 5532
chr14_-_118052235 1.46 ENSMUST00000022725.2
dopachrome tautomerase
chr13_+_113035111 1.46 ENSMUST00000180543.1
ENSMUST00000181568.1
ENSMUST00000109244.2
ENSMUST00000181117.1
ENSMUST00000181741.1
cell division cycle 20B
chr4_-_49549523 1.45 ENSMUST00000029987.9
aldolase B, fructose-bisphosphate
chr9_-_29412204 1.45 ENSMUST00000115237.1
neurotrimin
chr18_+_21001292 1.45 ENSMUST00000072847.5
ENSMUST00000052396.5
ring finger protein 138
chr13_-_93674300 1.44 ENSMUST00000015941.7
betaine-homocysteine methyltransferase 2
chr17_-_90088343 1.44 ENSMUST00000173917.1
neurexin I
chr9_-_121916288 1.43 ENSMUST00000062474.4
cytochrome P450, family 8, subfamily b, polypeptide 1
chr1_-_130940073 1.43 ENSMUST00000112465.1
interleukin 19
chr1_-_155146755 1.43 ENSMUST00000027744.8
major histocompatibility complex, class I-related
chrX_+_160768013 1.41 ENSMUST00000033650.7
retinoschisis (X-linked, juvenile) 1 (human)
chr19_+_46623387 1.40 ENSMUST00000111855.4
WW domain binding protein 1 like
chr18_+_37355271 1.40 ENSMUST00000051163.1
protocadherin beta 8
chr1_+_45311538 1.40 ENSMUST00000087883.6
collagen, type III, alpha 1
chr13_+_47122719 1.39 ENSMUST00000068891.4
ring finger protein 144B
chr2_+_160880642 1.39 ENSMUST00000109456.2
lipin 3
chr18_+_37484955 1.38 ENSMUST00000053856.4
protocadherin beta 17
chr10_+_80249106 1.37 ENSMUST00000105364.1
NADH dehydrogenase (ubiquinone) Fe-S protein 7
chr7_+_44216456 1.36 ENSMUST00000074359.2
kallikrein 1-related peptidase b5
chr1_+_177729814 1.36 ENSMUST00000016106.5
RIKEN cDNA 1700016C15 gene
chrM_+_7759 1.34 ENSMUST00000082407.1
ENSMUST00000082408.1
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chr8_-_45410539 1.33 ENSMUST00000034056.4
ENSMUST00000167106.1
toll-like receptor 3
chr3_+_60031754 1.30 ENSMUST00000029325.3
arylacetamide deacetylase (esterase)
chr1_-_164935522 1.28 ENSMUST00000027860.7
chemokine (C motif) ligand 1
chr15_-_65912254 1.26 ENSMUST00000079776.7
ENSMUST00000060522.4
otoconin 90
chr19_-_24031006 1.26 ENSMUST00000096164.4
family with sequence similarity 189, member A2
chr9_-_48480540 1.26 ENSMUST00000034524.3
REX2, RNA exonuclease 2 homolog (S. cerevisiae)
chr2_+_59484645 1.24 ENSMUST00000028369.5
death associated protein-like 1
chr10_-_121311034 1.24 ENSMUST00000064107.5
TBC1 domain family, member 30
chrX_-_85776606 1.22 ENSMUST00000142152.1
ENSMUST00000156390.1
ENSMUST00000113978.2
glycerol kinase
chr3_-_96926020 1.22 ENSMUST00000062944.5
gap junction protein, alpha 8
chr3_-_98588807 1.20 ENSMUST00000178221.1
predicted gene 10681
chr14_-_16575456 1.18 ENSMUST00000063750.6
retinoic acid receptor, beta
chr4_+_102254739 1.16 ENSMUST00000106907.2
phosphodiesterase 4B, cAMP specific
chr6_+_65590382 1.16 ENSMUST00000114236.1
TNFAIP3 interacting protein 3
chr2_-_69712461 1.14 ENSMUST00000102706.3
ENSMUST00000073152.6
FAST kinase domains 1
chr17_+_36772910 1.13 ENSMUST00000041531.6
histocompatibility 2, M region locus 10.5
chr2_+_55411790 1.13 ENSMUST00000155997.1
ENSMUST00000128307.1
predicted gene 14033
chr1_+_191717834 1.12 ENSMUST00000110855.1
ENSMUST00000133076.1
lysophosphatidylglycerol acyltransferase 1
chr14_-_63177793 1.08 ENSMUST00000054963.9
farnesyl diphosphate farnesyl transferase 1
chr16_+_21891969 1.08 ENSMUST00000042065.6
mitogen-activated protein kinase kinase kinase 13
chr9_+_107888129 1.07 ENSMUST00000035202.2
MON1 homolog A (yeast)
chr17_-_25081138 1.07 ENSMUST00000024984.6
transmembrane protein 204
chr1_+_131867224 1.05 ENSMUST00000112386.1
ENSMUST00000027693.7
RAB7, member RAS oncogene family-like 1
chr11_+_49280150 1.05 ENSMUST00000078932.1
olfactory receptor 1393
chr6_-_42472200 1.04 ENSMUST00000170504.1
olfactory receptor 457
chr8_+_123062942 1.02 ENSMUST00000142541.1
ENSMUST00000125975.1
spastic paraplegia 7 homolog (human)
chr11_-_83530505 0.98 ENSMUST00000035938.2
chemokine (C-C motif) ligand 5
chr18_+_7869342 0.97 ENSMUST00000092112.4
ENSMUST00000172018.1
ENSMUST00000168446.1
WW domain containing adaptor with coiled-coil
chr11_-_98329641 0.96 ENSMUST00000041685.6
neurogenic differentiation 2
chr4_+_141278433 0.95 ENSMUST00000142429.1
predicted gene 13056
chr3_+_79884931 0.95 ENSMUST00000135021.1
family with sequence similarity 198, member B
chr6_-_12109583 0.94 ENSMUST00000080891.5
predicted gene 6578
chr10_-_53647080 0.94 ENSMUST00000169866.1
family with sequence similarity 184, member A

Network of associatons between targets according to the STRING database.

First level regulatory network of Sox18_Sox12

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.9 14.8 GO:0071492 cellular response to UV-A(GO:0071492)
4.4 61.6 GO:0015747 urate transport(GO:0015747)
4.2 16.7 GO:0010986 regulation of high-density lipoprotein particle clearance(GO:0010982) positive regulation of lipoprotein particle clearance(GO:0010986)
3.6 10.7 GO:0002353 plasma kallikrein-kinin cascade(GO:0002353) activation of plasma proteins involved in acute inflammatory response(GO:0002541)
2.8 19.9 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
2.2 6.6 GO:0018879 biphenyl metabolic process(GO:0018879)
2.0 21.9 GO:0043651 linoleic acid metabolic process(GO:0043651)
1.3 19.7 GO:0052695 cellular glucuronidation(GO:0052695)
1.3 5.3 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
1.3 3.8 GO:2000295 regulation of hydrogen peroxide catabolic process(GO:2000295)
1.1 3.3 GO:0070342 brown fat cell proliferation(GO:0070342) regulation of brown fat cell proliferation(GO:0070347)
1.1 8.7 GO:0045919 positive regulation of cytolysis(GO:0045919)
1.0 3.0 GO:0061402 positive regulation of transcription from RNA polymerase II promoter in response to acidic pH(GO:0061402)
0.9 8.3 GO:0035754 B cell chemotaxis(GO:0035754)
0.9 3.7 GO:0006742 NADP catabolic process(GO:0006742)
0.8 2.5 GO:0099526 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.8 2.5 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.8 2.4 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.8 2.3 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.7 2.8 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.7 3.9 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.6 2.5 GO:0036343 psychomotor behavior(GO:0036343)
0.6 5.4 GO:0071830 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830)
0.6 4.1 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.6 2.9 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.6 3.4 GO:0006068 ethanol catabolic process(GO:0006068)
0.6 2.8 GO:0002481 antigen processing and presentation of exogenous peptide antigen via MHC class Ib(GO:0002477) antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent(GO:0002481)
0.6 2.3 GO:0051344 L-ascorbic acid biosynthetic process(GO:0019853) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344) positive regulation of calcium-transporting ATPase activity(GO:1901896) regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.6 2.2 GO:0046351 disaccharide biosynthetic process(GO:0046351)
0.5 4.1 GO:0071494 cellular response to UV-C(GO:0071494)
0.5 2.1 GO:0016062 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.5 3.5 GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.5 2.0 GO:0002780 antimicrobial peptide biosynthetic process(GO:0002777) antibacterial peptide biosynthetic process(GO:0002780)
0.5 1.5 GO:0006583 melanin biosynthetic process from tyrosine(GO:0006583)
0.5 1.9 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.5 1.8 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.4 10.8 GO:0035634 response to stilbenoid(GO:0035634)
0.4 1.5 GO:0006001 fructose catabolic process(GO:0006001) NADH oxidation(GO:0006116) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) glycolytic process through fructose-1-phosphate(GO:0061625)
0.4 3.6 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.4 1.4 GO:0090126 protein complex assembly involved in synapse maturation(GO:0090126)
0.3 1.7 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.3 8.9 GO:0032402 melanosome transport(GO:0032402) anagen(GO:0042640)
0.3 2.1 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.3 1.7 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.3 1.0 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.3 1.6 GO:1903587 negative regulation of peptidyl-serine dephosphorylation(GO:1902309) regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
0.3 1.0 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.3 3.2 GO:0097501 stress response to metal ion(GO:0097501)
0.3 2.2 GO:0036438 maintenance of lens transparency(GO:0036438)
0.3 5.2 GO:0051608 histamine transport(GO:0051608)
0.3 1.8 GO:1902965 regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
0.3 1.8 GO:0033762 response to glucagon(GO:0033762)
0.3 1.4 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.3 3.6 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.3 2.5 GO:0002756 MyD88-independent toll-like receptor signaling pathway(GO:0002756)
0.3 1.1 GO:0016128 phytosteroid metabolic process(GO:0016128) phytosteroid biosynthetic process(GO:0016129)
0.3 3.4 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.3 2.8 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.3 2.0 GO:0019695 choline metabolic process(GO:0019695)
0.2 1.4 GO:0071267 amino acid salvage(GO:0043102) L-methionine salvage(GO:0071267)
0.2 1.8 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.2 0.7 GO:1900135 positive regulation of renin secretion into blood stream(GO:1900135)
0.2 1.1 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.2 0.6 GO:1900477 negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter(GO:1900477)
0.2 2.1 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.2 8.9 GO:0006958 complement activation, classical pathway(GO:0006958)
0.2 1.6 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.2 1.6 GO:0015961 diadenosine polyphosphate catabolic process(GO:0015961)
0.2 0.7 GO:0006788 heme oxidation(GO:0006788)
0.2 2.3 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.2 0.7 GO:1903445 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.2 1.7 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.2 1.3 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.2 2.6 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.2 0.5 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.2 0.8 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.2 0.3 GO:0036518 chemorepulsion of dopaminergic neuron axon(GO:0036518)
0.1 0.6 GO:0003273 cell migration involved in endocardial cushion formation(GO:0003273) condensed mesenchymal cell proliferation(GO:0072137)
0.1 0.4 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.1 0.7 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.1 1.1 GO:0019532 oxalate transport(GO:0019532)
0.1 0.8 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.1 0.4 GO:0050973 detection of mechanical stimulus involved in equilibrioception(GO:0050973)
0.1 0.5 GO:1900533 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.1 0.9 GO:0090400 stress-induced premature senescence(GO:0090400)
0.1 0.6 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.1 3.0 GO:0042036 negative regulation of cytokine biosynthetic process(GO:0042036)
0.1 2.4 GO:0043383 negative T cell selection(GO:0043383)
0.1 3.7 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.1 0.8 GO:0034145 positive regulation of toll-like receptor 4 signaling pathway(GO:0034145)
0.1 2.2 GO:0042226 interleukin-6 biosynthetic process(GO:0042226)
0.1 0.6 GO:0070197 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.1 7.1 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.1 2.9 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 0.6 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.1 0.6 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.1 1.2 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.1 3.4 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 3.6 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.1 4.0 GO:0070207 protein homotrimerization(GO:0070207)
0.1 1.5 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.1 1.2 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 3.3 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.1 0.6 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 0.7 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.1 13.2 GO:0016052 carbohydrate catabolic process(GO:0016052)
0.1 2.2 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 1.5 GO:0033194 response to hydroperoxide(GO:0033194)
0.1 0.2 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1 3.9 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.1 0.2 GO:0002305 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.1 0.3 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.1 GO:1902524 positive regulation of protein K63-linked ubiquitination(GO:1902523) positive regulation of protein K48-linked ubiquitination(GO:1902524)
0.1 0.8 GO:0007343 egg activation(GO:0007343)
0.1 0.9 GO:0097264 self proteolysis(GO:0097264)
0.1 0.3 GO:1990839 response to endothelin(GO:1990839)
0.1 0.4 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.1 2.6 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.1 2.9 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.1 0.7 GO:0046549 retinal cone cell development(GO:0046549)
0.1 1.1 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
0.1 0.5 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 0.6 GO:0019682 pentose-phosphate shunt(GO:0006098) glyceraldehyde-3-phosphate metabolic process(GO:0019682)
0.0 1.4 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 1.4 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 1.0 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.0 3.6 GO:0007569 cell aging(GO:0007569)
0.0 2.5 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 6.4 GO:0007601 visual perception(GO:0007601)
0.0 0.3 GO:0010825 positive regulation of centrosome duplication(GO:0010825)
0.0 2.2 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.0 0.2 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.0 4.8 GO:0007098 centrosome cycle(GO:0007098)
0.0 0.5 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.1 GO:0050883 musculoskeletal movement, spinal reflex action(GO:0050883)
0.0 0.9 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.2 GO:0050957 equilibrioception(GO:0050957)
0.0 1.9 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.0 0.2 GO:0006108 malate metabolic process(GO:0006108)
0.0 1.6 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.0 2.4 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.0 0.5 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 0.9 GO:0048147 negative regulation of fibroblast proliferation(GO:0048147)
0.0 1.1 GO:0001945 lymph vessel development(GO:0001945)
0.0 1.2 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.0 0.9 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 1.1 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.5 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.5 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 0.8 GO:0021904 dorsal/ventral neural tube patterning(GO:0021904)
0.0 0.2 GO:0060903 positive regulation of meiosis I(GO:0060903)
0.0 1.5 GO:0002066 columnar/cuboidal epithelial cell development(GO:0002066)
0.0 0.1 GO:2000323 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259) negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.0 0.4 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 1.6 GO:0035418 protein localization to synapse(GO:0035418)
0.0 1.1 GO:0008089 anterograde axonal transport(GO:0008089)
0.0 1.7 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.2 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0 1.1 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 0.2 GO:0030035 microspike assembly(GO:0030035)
0.0 0.7 GO:0019731 antibacterial humoral response(GO:0019731)
0.0 0.7 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 4.2 GO:0030534 adult behavior(GO:0030534)
0.0 0.5 GO:0045109 intermediate filament organization(GO:0045109)
0.0 0.1 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.7 GO:0031424 keratinization(GO:0031424)
0.0 0.3 GO:0006625 protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 1.1 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 1.8 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 0.2 GO:1902916 positive regulation of protein polyubiquitination(GO:1902916)
0.0 0.5 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 1.0 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 1.0 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 3.5 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 0.2 GO:1902547 regulation of vascular endothelial growth factor signaling pathway(GO:1900746) regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902547)
0.0 1.0 GO:0045333 cellular respiration(GO:0045333)
0.0 0.3 GO:0032094 response to food(GO:0032094)
0.0 0.2 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.1 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.2 GO:0048665 neuron fate specification(GO:0048665)
0.0 0.6 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.1 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.7 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.8 2.5 GO:0044317 rod spherule(GO:0044317)
0.8 3.8 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.6 4.3 GO:0008091 spectrin(GO:0008091)
0.5 19.9 GO:0030673 axolemma(GO:0030673)
0.4 4.0 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.4 2.9 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.4 4.3 GO:0042612 MHC class I protein complex(GO:0042612)
0.3 1.5 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.3 10.4 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.3 1.0 GO:0005745 m-AAA complex(GO:0005745)
0.2 3.4 GO:0017119 Golgi transport complex(GO:0017119)
0.2 1.8 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.2 0.4 GO:0098636 protein complex involved in cell adhesion(GO:0098636)
0.2 9.5 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.2 3.0 GO:0008385 IkappaB kinase complex(GO:0008385)
0.2 1.6 GO:0070765 gamma-secretase complex(GO:0070765)
0.2 3.6 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.2 1.8 GO:0045275 respiratory chain complex III(GO:0045275)
0.2 3.8 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 3.4 GO:0042101 T cell receptor complex(GO:0042101)
0.1 1.5 GO:0000243 commitment complex(GO:0000243)
0.1 4.6 GO:0070469 respiratory chain(GO:0070469)
0.1 1.8 GO:0051286 cell tip(GO:0051286)
0.1 1.4 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.6 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.1 3.6 GO:0030904 retromer complex(GO:0030904)
0.1 3.9 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 0.4 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 1.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 4.7 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 1.7 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 19.3 GO:0008021 synaptic vesicle(GO:0008021)
0.1 12.4 GO:0072562 blood microparticle(GO:0072562)
0.1 2.5 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.1 5.3 GO:0032420 stereocilium(GO:0032420)
0.1 0.6 GO:0098644 complex of collagen trimers(GO:0098644)
0.1 18.4 GO:0005769 early endosome(GO:0005769)
0.1 3.8 GO:0042734 presynaptic membrane(GO:0042734)
0.1 21.0 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 2.1 GO:0034451 centriolar satellite(GO:0034451)
0.1 0.8 GO:0035631 CD40 receptor complex(GO:0035631)
0.1 2.9 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 0.9 GO:0032156 septin cytoskeleton(GO:0032156)
0.1 2.0 GO:0008180 COP9 signalosome(GO:0008180)
0.1 1.2 GO:0005922 connexon complex(GO:0005922)
0.0 0.2 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.6 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.0 1.4 GO:0035861 site of double-strand break(GO:0035861)
0.0 1.0 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 1.1 GO:0001533 cornified envelope(GO:0001533)
0.0 5.5 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 2.0 GO:0031526 brush border membrane(GO:0031526)
0.0 0.6 GO:0045495 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0 0.8 GO:0045095 keratin filament(GO:0045095)
0.0 0.4 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.7 GO:0060077 inhibitory synapse(GO:0060077)
0.0 43.9 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 0.2 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 3.6 GO:0001650 fibrillar center(GO:0001650)
0.0 23.2 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 1.8 GO:0043204 perikaryon(GO:0043204)
0.0 0.4 GO:0001741 XY body(GO:0001741)
0.0 2.8 GO:0019897 extrinsic component of plasma membrane(GO:0019897)
0.0 0.3 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.9 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.2 GO:0036064 ciliary basal body(GO:0036064)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
5.5 21.9 GO:0071614 linoleic acid epoxygenase activity(GO:0071614)
4.1 61.6 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
3.3 19.9 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
2.8 16.7 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
1.9 13.1 GO:0004556 alpha-amylase activity(GO:0004556)
1.9 11.1 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
1.7 5.2 GO:0005333 norepinephrine transmembrane transporter activity(GO:0005333)
1.3 3.9 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
1.3 8.8 GO:0001851 complement component C3b binding(GO:0001851)
1.2 3.6 GO:0004771 sterol esterase activity(GO:0004771)
1.2 3.5 GO:0004088 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.7 7.0 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.7 26.3 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.6 1.8 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.6 3.7 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.5 3.8 GO:0030492 hemoglobin binding(GO:0030492)
0.5 2.2 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.5 2.1 GO:0008802 betaine-aldehyde dehydrogenase activity(GO:0008802)
0.5 2.0 GO:0046997 oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.5 7.0 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.5 2.9 GO:0097016 L27 domain binding(GO:0097016)
0.5 4.7 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.5 4.1 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.4 12.5 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.4 3.4 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.4 1.6 GO:0047710 bis(5'-adenosyl)-triphosphatase activity(GO:0047710)
0.4 11.1 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.3 1.7 GO:0008384 IkappaB kinase activity(GO:0008384)
0.3 1.0 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.3 1.8 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.3 1.4 GO:0097109 neuroligin family protein binding(GO:0097109)
0.3 3.3 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.3 6.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 1.4 GO:0008172 S-methyltransferase activity(GO:0008172)
0.2 1.7 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.2 1.4 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.2 4.4 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.2 1.8 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.2 2.2 GO:0050308 sugar-phosphatase activity(GO:0050308)
0.2 2.5 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.2 3.6 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.2 2.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.2 0.7 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.2 0.6 GO:0047936 glucose 1-dehydrogenase [NAD(P)] activity(GO:0047936)
0.2 3.9 GO:0004385 guanylate kinase activity(GO:0004385)
0.2 1.5 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.2 3.0 GO:0042165 neurotransmitter binding(GO:0042165)
0.2 4.2 GO:0005537 mannose binding(GO:0005537)
0.2 0.5 GO:0004782 sulfinoalanine decarboxylase activity(GO:0004782)
0.2 2.3 GO:0003796 lysozyme activity(GO:0003796)
0.2 0.8 GO:0004883 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.1 0.9 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.1 0.7 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 0.9 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.1 0.4 GO:0035827 rubidium ion transmembrane transporter activity(GO:0035827)
0.1 0.7 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 16.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 3.2 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 2.9 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.1 0.5 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1 1.4 GO:0016776 phosphotransferase activity, phosphate group as acceptor(GO:0016776)
0.1 2.4 GO:0001848 complement binding(GO:0001848)
0.1 0.6 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 2.8 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 1.5 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.1 0.9 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 2.5 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 1.7 GO:0070403 NAD+ binding(GO:0070403)
0.1 1.6 GO:0070402 NADPH binding(GO:0070402)
0.1 1.5 GO:0016289 CoA hydrolase activity(GO:0016289)
0.1 1.4 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 1.3 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 3.2 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 2.9 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.3 GO:0048408 epidermal growth factor binding(GO:0048408)
0.1 0.8 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.1 1.2 GO:0070513 death domain binding(GO:0070513)
0.1 1.2 GO:0005243 gap junction channel activity(GO:0005243)
0.1 0.9 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 7.3 GO:1990782 protein tyrosine kinase binding(GO:1990782)
0.1 0.5 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 0.2 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.1 3.6 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 1.1 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 0.2 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.1 2.0 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 1.2 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.2 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 4.1 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.8 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 1.1 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 2.5 GO:0005549 odorant binding(GO:0005549)
0.0 1.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 1.1 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 1.1 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.8 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 4.8 GO:0008201 heparin binding(GO:0008201)
0.0 0.8 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.2 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.5 GO:0004549 tRNA-specific ribonuclease activity(GO:0004549)
0.0 0.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.1 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 0.4 GO:0035198 miRNA binding(GO:0035198)
0.0 0.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.6 GO:0015215 nucleotide transmembrane transporter activity(GO:0015215)
0.0 0.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.6 GO:0033558 histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558)
0.0 1.3 GO:0030507 spectrin binding(GO:0030507)
0.0 1.0 GO:0070888 E-box binding(GO:0070888)
0.0 2.0 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.0 1.8 GO:0051117 ATPase binding(GO:0051117)
0.0 0.8 GO:0005109 frizzled binding(GO:0005109)
0.0 0.2 GO:0000182 rDNA binding(GO:0000182)
0.0 1.0 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 1.3 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 2.4 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 1.3 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 0.3 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.1 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.3 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.7 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 2.2 GO:0005125 cytokine activity(GO:0005125)
0.0 0.8 GO:0004540 ribonuclease activity(GO:0004540)
0.0 0.7 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.3 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.7 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.0 0.4 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.1 GO:1901612 cardiolipin binding(GO:1901612)
0.0 6.4 GO:0005509 calcium ion binding(GO:0005509)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 10.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 10.1 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.1 1.8 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 3.3 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 1.6 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 3.9 PID FOXO PATHWAY FoxO family signaling
0.1 5.2 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 5.7 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 3.8 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.1 14.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 1.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.2 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.6 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 3.2 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 1.1 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 1.3 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.9 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 1.5 ST GA13 PATHWAY G alpha 13 Pathway
0.0 0.3 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.2 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.7 PID RB 1PATHWAY Regulation of retinoblastoma protein

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.8 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.9 11.2 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.8 11.0 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.7 15.4 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.6 8.3 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.6 8.3 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.5 4.2 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.4 4.0 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.3 3.6 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.3 3.4 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.3 18.3 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.3 3.3 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.2 3.9 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.2 2.4 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.2 2.8 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.2 1.3 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 0.4 REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
0.1 3.2 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 1.6 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.1 2.7 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 1.7 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 4.3 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 1.6 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 8.1 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 3.7 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 0.7 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 1.4 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 3.9 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.1 0.6 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 1.5 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 2.3 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 1.2 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 4.0 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.1 2.3 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 3.4 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 1.8 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 1.2 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 1.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.7 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 2.1 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 1.4 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.5 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.3 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.3 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 2.2 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 3.5 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.2 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.2 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.5 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.6 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions