Motif ID: Sox2

Z-value: 2.609


Transcription factors associated with Sox2:

Gene SymbolEntrez IDGene Name
Sox2 ENSMUSG00000074637.4 Sox2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox2mm10_v2_chr3_+_34649987_346500050.401.7e-02Click!


Activity profile for motif Sox2.

activity profile for motif Sox2


Sorted Z-values histogram for motif Sox2

Sorted Z-values for motif Sox2



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_-_134915512 25.474 ENSMUST00000008987.4
Cldn13
claudin 13
chr10_+_43579161 23.121 ENSMUST00000058714.8
Cd24a
CD24a antigen
chr7_+_45216671 21.497 ENSMUST00000134420.1
Tead2
TEA domain family member 2
chr4_+_115057683 21.437 ENSMUST00000161601.1
Tal1
T cell acute lymphocytic leukemia 1
chr7_-_142661305 18.192 ENSMUST00000105936.1
Igf2
insulin-like growth factor 2
chr11_+_116531097 15.023 ENSMUST00000138840.1
Sphk1
sphingosine kinase 1
chr16_-_36367623 13.408 ENSMUST00000096089.2
BC100530
cDNA sequence BC100530
chr16_-_17125106 12.912 ENSMUST00000093336.6
2610318N02Rik
RIKEN cDNA 2610318N02 gene
chr3_-_98859774 12.514 ENSMUST00000107016.3
ENSMUST00000149768.1
Hsd3b1

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1

chr3_-_98859753 11.869 ENSMUST00000029465.6
Hsd3b1
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
chr6_+_86628174 11.661 ENSMUST00000043400.6
Asprv1
aspartic peptidase, retroviral-like 1
chr5_+_44100442 11.517 ENSMUST00000072800.4
Gm16401
predicted gene 16401
chr9_-_103480328 11.485 ENSMUST00000124310.2
Bfsp2
beaded filament structural protein 2, phakinin
chr18_+_82554463 11.145 ENSMUST00000062446.7
ENSMUST00000102812.4
ENSMUST00000075372.5
ENSMUST00000080658.4
ENSMUST00000152071.1
ENSMUST00000114674.3
ENSMUST00000142850.1
ENSMUST00000133193.1
ENSMUST00000123251.1
ENSMUST00000153478.1
ENSMUST00000132369.1
Mbp










myelin basic protein










chr6_-_83527452 10.855 ENSMUST00000141904.1
Actg2
actin, gamma 2, smooth muscle, enteric
chr1_-_132390301 10.694 ENSMUST00000132435.1
Tmcc2
transmembrane and coiled-coil domains 2
chr4_+_115057410 10.531 ENSMUST00000136946.1
Tal1
T cell acute lymphocytic leukemia 1
chr3_-_84480419 10.292 ENSMUST00000107689.1
Fhdc1
FH2 domain containing 1
chr7_-_103853199 10.273 ENSMUST00000033229.3
Hbb-y
hemoglobin Y, beta-like embryonic chain
chr2_+_84734050 9.973 ENSMUST00000090729.2
Ypel4
yippee-like 4 (Drosophila)
chr15_-_103251465 9.286 ENSMUST00000133600.1
ENSMUST00000134554.1
ENSMUST00000156927.1
ENSMUST00000149111.1
ENSMUST00000132836.1
Nfe2




nuclear factor, erythroid derived 2




chr4_+_141010644 9.196 ENSMUST00000071977.8
Mfap2
microfibrillar-associated protein 2
chr17_-_79355082 9.172 ENSMUST00000068958.7
Cdc42ep3
CDC42 effector protein (Rho GTPase binding) 3
chr11_-_96005872 9.155 ENSMUST00000013559.2
Igf2bp1
insulin-like growth factor 2 mRNA binding protein 1
chr1_+_136131382 9.143 ENSMUST00000075164.4
Kif21b
kinesin family member 21B
chr12_+_24831583 9.122 ENSMUST00000110942.3
ENSMUST00000078902.6
Mboat2

membrane bound O-acyltransferase domain containing 2

chr10_-_21160925 9.070 ENSMUST00000020158.6
Myb
myeloblastosis oncogene
chr4_+_136172367 9.058 ENSMUST00000061721.5
E2f2
E2F transcription factor 2
chr13_+_117220584 9.049 ENSMUST00000022242.7
Emb
embigin
chr4_-_148130678 9.011 ENSMUST00000030862.4
Draxin
dorsal inhibitory axon guidance protein
chr7_-_120982260 8.958 ENSMUST00000033169.8
Cdr2
cerebellar degeneration-related 2
chr9_+_58014990 8.901 ENSMUST00000034874.7
Cyp11a1
cytochrome P450, family 11, subfamily a, polypeptide 1
chr2_+_156840966 8.825 ENSMUST00000109564.1
Tgif2
TGFB-induced factor homeobox 2
chr3_-_20275659 8.644 ENSMUST00000011607.5
Cpb1
carboxypeptidase B1 (tissue)
chr12_-_36042476 8.532 ENSMUST00000020896.8
Tspan13
tetraspanin 13
chr4_+_62965560 8.369 ENSMUST00000030043.6
ENSMUST00000107415.1
ENSMUST00000064814.5
Zfp618


zinc finger protein 618


chr11_+_58948890 8.361 ENSMUST00000078267.3
Hist3h2ba
histone cluster 3, H2ba
chr14_+_80000292 8.347 ENSMUST00000088735.3
Olfm4
olfactomedin 4
chr17_+_48232755 8.282 ENSMUST00000113251.3
ENSMUST00000048782.6
Trem1

triggering receptor expressed on myeloid cells 1

chr3_-_54915867 8.152 ENSMUST00000070342.3
Sertm1
serine rich and transmembrane domain containing 1
chr11_+_78301529 8.116 ENSMUST00000045026.3
Spag5
sperm associated antigen 5
chr2_-_168767136 8.060 ENSMUST00000029061.5
ENSMUST00000103074.1
Sall4

sal-like 4 (Drosophila)

chr7_+_45215753 8.041 ENSMUST00000033060.6
ENSMUST00000155313.1
ENSMUST00000107801.1
Tead2


TEA domain family member 2


chr11_+_11686213 7.820 ENSMUST00000076700.4
ENSMUST00000048122.6
Ikzf1

IKAROS family zinc finger 1

chr15_-_103255433 7.816 ENSMUST00000075192.6
Nfe2
nuclear factor, erythroid derived 2
chrX_+_93654863 7.710 ENSMUST00000113933.2
Pcyt1b
phosphate cytidylyltransferase 1, choline, beta isoform
chr2_+_155611175 7.646 ENSMUST00000092995.5
Myh7b
myosin, heavy chain 7B, cardiac muscle, beta
chr15_-_36879816 7.506 ENSMUST00000100713.2
Gm10384
predicted gene 10384
chr2_-_170406501 7.482 ENSMUST00000154650.1
Bcas1
breast carcinoma amplified sequence 1
chr2_+_131491958 7.446 ENSMUST00000110181.1
ENSMUST00000110180.1
Smox

spermine oxidase

chr4_-_130574150 7.407 ENSMUST00000105993.3
Nkain1
Na+/K+ transporting ATPase interacting 1
chr5_-_44099220 7.380 ENSMUST00000165909.1
Prom1
prominin 1
chr2_+_131491764 7.363 ENSMUST00000028806.5
ENSMUST00000110179.2
ENSMUST00000110189.2
ENSMUST00000110182.2
ENSMUST00000110183.2
ENSMUST00000110186.2
ENSMUST00000110188.1
Smox






spermine oxidase






chr9_+_111004811 7.265 ENSMUST00000080872.4
Gm10030
predicted gene 10030
chr2_+_4559742 7.226 ENSMUST00000176828.1
Frmd4a
FERM domain containing 4A
chr12_+_24708984 7.151 ENSMUST00000154588.1
Rrm2
ribonucleotide reductase M2
chr15_-_96642883 7.139 ENSMUST00000088452.4
Slc38a1
solute carrier family 38, member 1
chr17_+_12119274 7.102 ENSMUST00000024594.2
Agpat4
1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta)
chr7_+_100493337 7.037 ENSMUST00000126534.1
Ucp2
uncoupling protein 2 (mitochondrial, proton carrier)
chr11_+_62077018 7.002 ENSMUST00000092415.5
Specc1
sperm antigen with calponin homology and coiled-coil domains 1
chr13_-_55488038 6.989 ENSMUST00000109921.2
ENSMUST00000109923.2
ENSMUST00000021950.8
Dbn1


drebrin 1


chr7_-_116038734 6.933 ENSMUST00000166877.1
Sox6
SRY-box containing gene 6
chr8_+_123332676 6.847 ENSMUST00000010298.6
Spire2
spire homolog 2 (Drosophila)
chr11_+_11685909 6.745 ENSMUST00000065433.5
Ikzf1
IKAROS family zinc finger 1
chr2_+_120476911 6.656 ENSMUST00000110716.1
ENSMUST00000028748.6
ENSMUST00000090028.5
ENSMUST00000110719.2
Capn3



calpain 3



chr6_-_87590701 6.644 ENSMUST00000050887.7
Prokr1
prokineticin receptor 1
chr8_+_123411424 6.600 ENSMUST00000071134.3
Tubb3
tubulin, beta 3 class III
chr17_-_35000848 6.596 ENSMUST00000166828.3
D17H6S56E-5
DNA segment, Chr 17, human D6S56E 5
chrX_+_93675088 6.545 ENSMUST00000045898.3
Pcyt1b
phosphate cytidylyltransferase 1, choline, beta isoform
chrX_+_134295225 6.522 ENSMUST00000037687.7
Tmem35
transmembrane protein 35
chr5_-_138171248 6.484 ENSMUST00000153867.1
Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chr10_-_30655859 6.474 ENSMUST00000092610.4
Ncoa7
nuclear receptor coactivator 7
chr10_-_122047293 6.435 ENSMUST00000020322.5
ENSMUST00000081688.6
Srgap1

SLIT-ROBO Rho GTPase activating protein 1

chr7_+_100493795 6.431 ENSMUST00000129324.1
Ucp2
uncoupling protein 2 (mitochondrial, proton carrier)
chr1_-_182019927 6.376 ENSMUST00000078719.6
ENSMUST00000111030.3
ENSMUST00000177811.1
ENSMUST00000111024.3
ENSMUST00000111025.2
Enah




enabled homolog (Drosophila)




chr5_-_108749448 6.372 ENSMUST00000068946.7
Rnf212
ring finger protein 212
chrX_+_21484532 6.323 ENSMUST00000089188.2
Agtr2
angiotensin II receptor, type 2
chr7_-_100514800 6.252 ENSMUST00000054923.7
Dnajb13
DnaJ (Hsp40) related, subfamily B, member 13
chr7_-_115824699 6.207 ENSMUST00000169129.1
Sox6
SRY-box containing gene 6
chr2_-_168767029 6.145 ENSMUST00000075044.3
Sall4
sal-like 4 (Drosophila)
chr16_+_18127607 6.104 ENSMUST00000059589.5
Rtn4r
reticulon 4 receptor
chr6_-_83527773 6.085 ENSMUST00000152029.1
Actg2
actin, gamma 2, smooth muscle, enteric
chr18_+_34624621 6.079 ENSMUST00000167161.1
Kif20a
kinesin family member 20A
chr5_-_138170992 6.017 ENSMUST00000139983.1
Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chr7_+_141061274 6.003 ENSMUST00000048002.5
B4galnt4
beta-1,4-N-acetyl-galactosaminyl transferase 4
chr10_-_37138863 6.002 ENSMUST00000092584.5
Marcks
myristoylated alanine rich protein kinase C substrate
chr11_-_69560186 5.997 ENSMUST00000004036.5
Efnb3
ephrin B3
chr5_-_131538687 5.979 ENSMUST00000161374.1
Auts2
autism susceptibility candidate 2
chr13_+_52583437 5.963 ENSMUST00000118756.1
Syk
spleen tyrosine kinase
chr12_-_54986363 5.961 ENSMUST00000173433.1
ENSMUST00000173803.1
Baz1a
Gm20403
bromodomain adjacent to zinc finger domain 1A
predicted gene 20403
chr11_+_67277124 5.949 ENSMUST00000019625.5
Myh8
myosin, heavy polypeptide 8, skeletal muscle, perinatal
chr1_+_74409376 5.934 ENSMUST00000027366.6
Vil1
villin 1
chr1_+_153749496 5.932 ENSMUST00000182722.1
Rnasel
ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent)
chr4_-_83021102 5.921 ENSMUST00000071708.5
Frem1
Fras1 related extracellular matrix protein 1
chr3_+_14886426 5.920 ENSMUST00000029078.7
Car2
carbonic anhydrase 2
chr17_-_56476462 5.911 ENSMUST00000067538.5
Ptprs
protein tyrosine phosphatase, receptor type, S
chr12_-_54986328 5.889 ENSMUST00000038926.6
Baz1a
bromodomain adjacent to zinc finger domain 1A
chr11_+_32276400 5.871 ENSMUST00000020531.2
Hba-x
hemoglobin X, alpha-like embryonic chain in Hba complex
chr8_-_85365341 5.837 ENSMUST00000121972.1
Mylk3
myosin light chain kinase 3
chr11_+_3649759 5.827 ENSMUST00000140242.1
Morc2a
microrchidia 2A
chr2_-_131160006 5.805 ENSMUST00000103188.3
ENSMUST00000133602.1
ENSMUST00000028800.5
1700037H04Rik


RIKEN cDNA 1700037H04 gene


chr11_+_95010277 5.773 ENSMUST00000124735.1
Samd14
sterile alpha motif domain containing 14
chr3_+_88615367 5.770 ENSMUST00000176539.1
Arhgef2
rho/rac guanine nucleotide exchange factor (GEF) 2
chr8_-_85365317 5.733 ENSMUST00000034133.7
Mylk3
myosin light chain kinase 3
chr14_+_60378242 5.720 ENSMUST00000022561.6
Amer2
APC membrane recruitment 2
chr11_-_46312220 5.682 ENSMUST00000129474.1
ENSMUST00000093166.4
ENSMUST00000165599.2
Cyfip2


cytoplasmic FMR1 interacting protein 2


chr16_+_11066292 5.621 ENSMUST00000089011.4
Snn
stannin
chr7_-_143460989 5.618 ENSMUST00000167912.1
ENSMUST00000037287.6
Cdkn1c

cyclin-dependent kinase inhibitor 1C (P57)

chr5_-_138171216 5.618 ENSMUST00000147920.1
Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chr2_-_164389095 5.591 ENSMUST00000167427.1
Slpi
secretory leukocyte peptidase inhibitor
chr11_-_74590065 5.557 ENSMUST00000145524.1
ENSMUST00000047488.7
Rap1gap2

RAP1 GTPase activating protein 2

chr4_+_107830958 5.556 ENSMUST00000106731.2
Lrp8
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
chr18_+_34625009 5.548 ENSMUST00000166044.1
Kif20a
kinesin family member 20A
chr2_+_157560078 5.525 ENSMUST00000153739.2
ENSMUST00000173595.1
ENSMUST00000109526.1
ENSMUST00000173839.1
ENSMUST00000173041.1
ENSMUST00000173793.1
ENSMUST00000172487.1
ENSMUST00000088484.5
Nnat







neuronatin







chr3_+_153973436 5.484 ENSMUST00000089948.5
Slc44a5
solute carrier family 44, member 5
chr8_-_69184177 5.472 ENSMUST00000185176.1
Lzts1
leucine zipper, putative tumor suppressor 1
chr11_-_87108656 5.467 ENSMUST00000051395.8
Prr11
proline rich 11
chr2_-_101883010 5.426 ENSMUST00000154525.1
Prr5l
proline rich 5 like
chr7_-_84409959 5.425 ENSMUST00000085077.3
Arnt2
aryl hydrocarbon receptor nuclear translocator 2
chr19_-_5894100 5.410 ENSMUST00000055911.4
Tigd3
tigger transposable element derived 3
chr18_-_23981555 5.393 ENSMUST00000115829.1
Zscan30
zinc finger and SCAN domain containing 30
chr15_-_84557776 5.391 ENSMUST00000069476.4
Ldoc1l
leucine zipper, down-regulated in cancer 1-like
chr7_+_110777653 5.373 ENSMUST00000148292.1
Ampd3
adenosine monophosphate deaminase 3
chrX_-_164258186 5.328 ENSMUST00000112265.2
Bmx
BMX non-receptor tyrosine kinase
chr16_-_20426375 5.319 ENSMUST00000079158.6
Abcc5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr10_-_80421847 5.314 ENSMUST00000156244.1
Tcf3
transcription factor 3
chr7_-_142095266 5.293 ENSMUST00000039926.3
Dusp8
dual specificity phosphatase 8
chr19_-_46039621 5.279 ENSMUST00000056931.7
Ldb1
LIM domain binding 1
chr2_+_31950257 5.251 ENSMUST00000001920.7
Aif1l
allograft inflammatory factor 1-like
chr4_-_154928545 5.251 ENSMUST00000152687.1
Tnfrsf14
tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)
chr8_+_94977101 5.224 ENSMUST00000179619.1
Gpr56
G protein-coupled receptor 56
chr2_-_84822546 5.213 ENSMUST00000028471.5
Smtnl1
smoothelin-like 1
chrX_+_48519245 5.171 ENSMUST00000033430.2
Rab33a
RAB33A, member of RAS oncogene family
chrX_-_59568068 5.147 ENSMUST00000119833.1
ENSMUST00000131319.1
Fgf13

fibroblast growth factor 13

chr11_+_95009852 5.135 ENSMUST00000055947.3
Samd14
sterile alpha motif domain containing 14
chr1_-_93342734 5.129 ENSMUST00000027493.3
Pask
PAS domain containing serine/threonine kinase
chr11_+_69846610 5.097 ENSMUST00000152566.1
ENSMUST00000108633.2
Plscr3

phospholipid scramblase 3

chr4_-_132049058 5.091 ENSMUST00000105981.2
ENSMUST00000084253.3
ENSMUST00000141291.1
Epb4.1


erythrocyte protein band 4.1


chrX_-_143827391 5.078 ENSMUST00000087316.5
Capn6
calpain 6
chr10_+_41476314 4.983 ENSMUST00000119962.1
ENSMUST00000019967.9
ENSMUST00000099934.4
Mical1


microtubule associated monooxygenase, calponin and LIM domain containing 1


chr17_-_48409729 4.977 ENSMUST00000160319.1
ENSMUST00000159535.1
ENSMUST00000078800.6
ENSMUST00000046719.7
ENSMUST00000162460.1
Nfya




nuclear transcription factor-Y alpha




chr11_-_74590186 4.961 ENSMUST00000102521.1
Rap1gap2
RAP1 GTPase activating protein 2
chr6_-_88875035 4.949 ENSMUST00000145944.1
Podxl2
podocalyxin-like 2
chr7_+_45335256 4.929 ENSMUST00000085351.4
Hrc
histidine rich calcium binding protein
chr12_+_108605757 4.922 ENSMUST00000109854.2
Evl
Ena-vasodilator stimulated phosphoprotein
chr7_+_24897381 4.914 ENSMUST00000003469.7
Cd79a
CD79A antigen (immunoglobulin-associated alpha)
chr8_+_86745679 4.905 ENSMUST00000098532.2
Gm10638
predicted gene 10638
chr3_-_89338005 4.885 ENSMUST00000029674.7
Efna4
ephrin A4
chr6_-_67037399 4.882 ENSMUST00000043098.6
Gadd45a
growth arrest and DNA-damage-inducible 45 alpha
chr16_+_17233560 4.880 ENSMUST00000090190.5
ENSMUST00000115698.2
Hic2

hypermethylated in cancer 2

chr1_+_87404916 4.865 ENSMUST00000173152.1
ENSMUST00000173663.1
Gigyf2

GRB10 interacting GYF protein 2

chr2_-_114052804 4.836 ENSMUST00000090269.6
Actc1
actin, alpha, cardiac muscle 1
chr12_+_24708241 4.831 ENSMUST00000020980.5
Rrm2
ribonucleotide reductase M2
chr6_+_127887582 4.827 ENSMUST00000032501.4
Tspan11
tetraspanin 11
chr6_-_87335758 4.815 ENSMUST00000042025.9
Antxr1
anthrax toxin receptor 1
chr5_+_105415738 4.800 ENSMUST00000112707.1
Lrrc8b
leucine rich repeat containing 8 family, member B
chr12_-_101028983 4.798 ENSMUST00000068411.3
ENSMUST00000085096.3
Ccdc88c

coiled-coil domain containing 88C

chr1_+_153749414 4.754 ENSMUST00000086209.3
Rnasel
ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent)
chr6_-_148944750 4.744 ENSMUST00000111562.1
ENSMUST00000081956.5
Fam60a

family with sequence similarity 60, member A

chr4_+_43957678 4.741 ENSMUST00000107855.1
Glipr2
GLI pathogenesis-related 2
chr4_-_134012381 4.730 ENSMUST00000176113.1
Lin28a
lin-28 homolog A (C. elegans)
chr7_-_113347273 4.727 ENSMUST00000117577.1
Btbd10
BTB (POZ) domain containing 10
chr11_+_69846665 4.720 ENSMUST00000019605.2
Plscr3
phospholipid scramblase 3
chr1_+_139454747 4.720 ENSMUST00000053364.8
ENSMUST00000097554.3
Aspm

asp (abnormal spindle)-like, microcephaly associated (Drosophila)

chr5_+_26904682 4.676 ENSMUST00000120555.1
Dpp6
dipeptidylpeptidase 6
chr4_-_63403330 4.630 ENSMUST00000035724.4
Akna
AT-hook transcription factor
chr5_+_66676098 4.586 ENSMUST00000031131.9
Uchl1
ubiquitin carboxy-terminal hydrolase L1
chr12_-_16800674 4.568 ENSMUST00000162112.1
Greb1
gene regulated by estrogen in breast cancer protein
chr11_-_102819114 4.560 ENSMUST00000068933.5
Gjc1
gap junction protein, gamma 1
chr6_+_128375456 4.545 ENSMUST00000100926.2
4933413G19Rik
RIKEN cDNA 4933413G19 gene
chr9_+_21029373 4.513 ENSMUST00000001040.5
Icam4
intercellular adhesion molecule 4, Landsteiner-Wiener blood group
chr5_+_37245792 4.461 ENSMUST00000031004.7
Crmp1
collapsin response mediator protein 1
chr11_+_16951371 4.460 ENSMUST00000109635.1
ENSMUST00000061327.1
Fbxo48

F-box protein 48

chr16_-_20426322 4.433 ENSMUST00000115547.2
ENSMUST00000096199.4
Abcc5

ATP-binding cassette, sub-family C (CFTR/MRP), member 5

chr16_-_20425881 4.412 ENSMUST00000077867.3
Abcc5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr7_-_25005895 4.363 ENSMUST00000102858.3
ENSMUST00000080882.6
Atp1a3

ATPase, Na+/K+ transporting, alpha 3 polypeptide

chr19_+_44293676 4.344 ENSMUST00000026221.5
Scd2
stearoyl-Coenzyme A desaturase 2
chr18_-_43737186 4.275 ENSMUST00000025381.2
Spink3
serine peptidase inhibitor, Kazal type 3
chr14_+_31019183 4.272 ENSMUST00000052239.5
Pbrm1
polybromo 1
chr4_-_58499398 4.268 ENSMUST00000107570.1
Lpar1
lysophosphatidic acid receptor 1
chr6_+_40964760 4.239 ENSMUST00000076638.5
1810009J06Rik
RIKEN cDNA 1810009J06 gene
chr12_-_115790884 4.227 ENSMUST00000081809.5
Ighv1-73
immunoglobulin heavy variable 1-73
chr11_+_96323253 4.221 ENSMUST00000093944.3
Hoxb3
homeobox B3
chr5_+_142702091 4.220 ENSMUST00000058418.7
Slc29a4
solute carrier family 29 (nucleoside transporters), member 4
chr8_+_109705549 4.202 ENSMUST00000034163.8
Zfp821
zinc finger protein 821
chr18_+_82475133 4.162 ENSMUST00000091789.4
ENSMUST00000114676.1
ENSMUST00000047865.7
Mbp


myelin basic protein


chr15_+_80173642 4.152 ENSMUST00000044970.6
Mgat3
mannoside acetylglucosaminyltransferase 3
chr10_+_128908907 4.150 ENSMUST00000105229.1
Cd63
CD63 antigen
chr11_+_87760533 4.139 ENSMUST00000039627.5
ENSMUST00000100644.3
Bzrap1

benzodiazepine receptor associated protein 1

chr19_-_47919269 4.128 ENSMUST00000095998.5
Itprip
inositol 1,4,5-triphosphate receptor interacting protein
chr10_-_79874233 4.117 ENSMUST00000166023.1
ENSMUST00000167707.1
ENSMUST00000165601.1
BC005764


cDNA sequence BC005764


chr10_+_17796256 4.115 ENSMUST00000037964.6
Txlnb
taxilin beta
chr16_+_19760902 4.111 ENSMUST00000119468.1
B3gnt5
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr16_-_18629864 4.108 ENSMUST00000096987.5
Sept5
septin 5
chr17_-_25433775 4.104 ENSMUST00000159610.1
ENSMUST00000159048.1
ENSMUST00000078496.5
Cacna1h


calcium channel, voltage-dependent, T type, alpha 1H subunit


chr4_-_128806045 4.096 ENSMUST00000106072.2
ENSMUST00000170934.1
Zfp362

zinc finger protein 362

chr4_+_48585193 4.088 ENSMUST00000107703.1
Tmeff1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr4_+_107802277 4.084 ENSMUST00000106733.2
ENSMUST00000030356.3
ENSMUST00000106732.2
ENSMUST00000126573.1
Lrp8



low density lipoprotein receptor-related protein 8, apolipoprotein e receptor



chr8_+_36094828 4.078 ENSMUST00000110492.1
D8Ertd82e
DNA segment, Chr 8, ERATO Doi 82, expressed
chr5_+_134676490 4.042 ENSMUST00000100641.2
Gm10369
predicted gene 10369

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
10.7 32.0 GO:0060217 hemangioblast cell differentiation(GO:0060217)
7.7 23.1 GO:0002842 positive regulation of T cell mediated immune response to tumor cell(GO:0002842)
5.1 15.3 GO:1904207 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
4.9 14.6 GO:0045660 positive regulation of neutrophil differentiation(GO:0045660)
2.5 7.5 GO:0010643 cell communication by chemical coupling(GO:0010643)
2.5 15.0 GO:0019371 cyclooxygenase pathway(GO:0019371)
2.5 7.4 GO:0072139 glomerular parietal epithelial cell differentiation(GO:0072139)
2.4 11.9 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
2.3 6.8 GO:0070649 formin-nucleated actin cable assembly(GO:0070649) formin-nucleated actin cable organization(GO:0110009)
2.3 18.2 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
2.2 9.0 GO:1905832 positive regulation of spindle assembly(GO:1905832)
2.2 6.7 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718) G1 to G0 transition involved in cell differentiation(GO:0070315)
2.2 6.6 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
2.1 6.4 GO:0006592 ornithine biosynthetic process(GO:0006592)
2.1 14.8 GO:0046208 spermine catabolic process(GO:0046208)
2.1 6.3 GO:1904158 axonemal central apparatus assembly(GO:1904158)
2.0 16.1 GO:0015671 oxygen transport(GO:0015671)
2.0 6.0 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
2.0 5.9 GO:0032849 positive regulation of cellular pH reduction(GO:0032849)
2.0 7.8 GO:0043973 histone H3-K4 acetylation(GO:0043973)
1.8 18.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
1.8 9.0 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
1.8 10.5 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
1.8 7.0 GO:0046898 response to cycloheximide(GO:0046898)
1.6 8.1 GO:0035984 response to trichostatin A(GO:0035983) cellular response to trichostatin A(GO:0035984)
1.6 9.6 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
1.6 6.3 GO:1904008 response to monosodium glutamate(GO:1904008) cellular response to monosodium glutamate(GO:1904009)
1.5 6.2 GO:0003349 epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
1.5 6.1 GO:0032696 negative regulation of interleukin-13 production(GO:0032696)
1.5 4.6 GO:0086053 AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
1.5 6.0 GO:0042223 positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401) positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425) cellular response to molecule of fungal origin(GO:0071226)
1.5 5.9 GO:1902896 terminal web assembly(GO:1902896)
1.4 17.1 GO:0034242 negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
1.4 12.4 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
1.3 16.1 GO:0021780 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
1.3 9.4 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
1.3 3.9 GO:1905564 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245) positive regulation of vascular endothelial cell proliferation(GO:1905564)
1.3 3.9 GO:0051466 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) positive regulation of corticotropin-releasing hormone secretion(GO:0051466)
1.3 9.1 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
1.3 3.9 GO:0003345 proepicardium cell migration involved in pericardium morphogenesis(GO:0003345)
1.3 2.6 GO:0002343 peripheral B cell selection(GO:0002343) B cell affinity maturation(GO:0002344)
1.3 3.9 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
1.3 6.4 GO:0035822 meiotic gene conversion(GO:0006311) gene conversion(GO:0035822)
1.3 10.1 GO:0071802 negative regulation of podosome assembly(GO:0071802)
1.2 3.7 GO:2000978 auditory receptor cell fate determination(GO:0042668) negative regulation of forebrain neuron differentiation(GO:2000978)
1.2 4.9 GO:0033380 protein localization to secretory granule(GO:0033366) protein localization to mast cell secretory granule(GO:0033367) protease localization to mast cell secretory granule(GO:0033368) maintenance of protein location in mast cell secretory granule(GO:0033370) T cell secretory granule organization(GO:0033371) maintenance of protease location in mast cell secretory granule(GO:0033373) protein localization to T cell secretory granule(GO:0033374) protease localization to T cell secretory granule(GO:0033375) maintenance of protein location in T cell secretory granule(GO:0033377) maintenance of protease location in T cell secretory granule(GO:0033379) granzyme B localization to T cell secretory granule(GO:0033380) maintenance of granzyme B location in T cell secretory granule(GO:0033382)
1.2 8.3 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
1.2 5.9 GO:0034163 regulation of toll-like receptor 9 signaling pathway(GO:0034163)
1.2 4.7 GO:0051661 regulation of asymmetric cell division(GO:0009786) maintenance of centrosome location(GO:0051661)
1.2 9.3 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
1.1 30.3 GO:0048368 lateral mesoderm development(GO:0048368)
1.1 4.5 GO:1904529 regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
1.1 4.3 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
1.1 18.4 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
1.1 3.2 GO:1902688 regulation of fermentation(GO:0043465) regulation of NAD metabolic process(GO:1902688) regulation of glucose catabolic process to lactate via pyruvate(GO:1904023)
1.1 4.3 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
1.1 4.3 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
1.0 8.2 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
1.0 7.1 GO:0006868 glutamine transport(GO:0006868)
1.0 4.8 GO:1903054 negative regulation of extracellular matrix organization(GO:1903054)
1.0 3.8 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
1.0 4.8 GO:1903756 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
1.0 5.7 GO:1903755 regulation of SUMO transferase activity(GO:1903182) positive regulation of SUMO transferase activity(GO:1903755)
0.9 2.8 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
0.9 11.0 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.9 14.3 GO:0006657 CDP-choline pathway(GO:0006657)
0.9 8.0 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.9 2.7 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.9 4.4 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.9 2.7 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.9 5.3 GO:0002326 B cell lineage commitment(GO:0002326)
0.9 7.0 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.9 12.8 GO:0033275 actin-myosin filament sliding(GO:0033275)
0.8 2.5 GO:0048012 hepatocyte growth factor receptor signaling pathway(GO:0048012)
0.8 15.2 GO:0070307 lens fiber cell development(GO:0070307)
0.8 4.1 GO:2000680 regulation of rubidium ion transport(GO:2000680)
0.8 8.2 GO:0090527 actin filament reorganization(GO:0090527)
0.8 11.3 GO:0051571 positive regulation of histone H3-K4 methylation(GO:0051571)
0.8 7.9 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.8 7.0 GO:0010587 miRNA catabolic process(GO:0010587)
0.8 5.4 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.8 4.6 GO:0007412 axon target recognition(GO:0007412)
0.8 3.1 GO:0036515 serotonergic neuron axon guidance(GO:0036515)
0.8 5.3 GO:0015808 L-alanine transport(GO:0015808)
0.8 14.3 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.7 1.5 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.7 3.6 GO:0006177 GMP biosynthetic process(GO:0006177)
0.7 0.7 GO:0060529 squamous basal epithelial stem cell differentiation involved in prostate gland acinus development(GO:0060529)
0.7 2.1 GO:1900149 positive regulation of Schwann cell migration(GO:1900149)
0.7 3.6 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.7 2.8 GO:0097393 post-embryonic appendage morphogenesis(GO:0035120) post-embryonic limb morphogenesis(GO:0035127) post-embryonic forelimb morphogenesis(GO:0035128) telomeric repeat-containing RNA transcription(GO:0097393) telomeric repeat-containing RNA transcription from RNA pol II promoter(GO:0097394) regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901580) negative regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901581) positive regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901582)
0.7 4.9 GO:0090281 negative regulation of calcium ion import(GO:0090281)
0.7 0.7 GO:1902460 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.7 1.4 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.7 5.6 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) negative regulation of serotonin uptake(GO:0051612)
0.7 2.1 GO:0071846 actin filament debranching(GO:0071846)
0.7 3.5 GO:1905709 negative regulation of mitochondrial membrane permeability(GO:0035795) negative regulation of membrane permeability(GO:1905709)
0.7 2.1 GO:0002270 plasmacytoid dendritic cell activation(GO:0002270)
0.7 2.0 GO:1990523 bone regeneration(GO:1990523)
0.7 3.4 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.7 3.4 GO:0002803 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.7 6.0 GO:0016198 axon choice point recognition(GO:0016198)
0.7 2.0 GO:0046436 D-serine catabolic process(GO:0036088) D-alanine family amino acid metabolic process(GO:0046144) D-alanine metabolic process(GO:0046436) D-alanine catabolic process(GO:0055130)
0.6 5.1 GO:0070091 glucagon secretion(GO:0070091) regulation of glucagon secretion(GO:0070092)
0.6 3.2 GO:0034144 negative regulation of toll-like receptor 4 signaling pathway(GO:0034144)
0.6 14.5 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.6 2.5 GO:0046351 disaccharide biosynthetic process(GO:0046351)
0.6 10.7 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.6 1.9 GO:1901074 aminophospholipid transport(GO:0015917) regulation of engulfment of apoptotic cell(GO:1901074)
0.6 2.5 GO:0072697 protein localization to cell cortex(GO:0072697)
0.6 11.6 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.6 5.4 GO:0038203 TORC2 signaling(GO:0038203)
0.6 10.8 GO:0010715 regulation of extracellular matrix disassembly(GO:0010715)
0.6 1.8 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.6 5.4 GO:0032264 IMP salvage(GO:0032264)
0.6 1.2 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.6 6.5 GO:0005513 detection of calcium ion(GO:0005513)
0.6 13.4 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.6 2.3 GO:0033580 protein glycosylation at cell surface(GO:0033575) protein galactosylation at cell surface(GO:0033580) protein galactosylation(GO:0042125)
0.6 1.1 GO:0061511 centriole elongation(GO:0061511)
0.6 2.8 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.6 2.3 GO:0021938 smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938) notochord regression(GO:0060032)
0.6 3.9 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.5 2.7 GO:0071593 lymphocyte aggregation(GO:0071593)
0.5 7.1 GO:0043045 DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.5 4.8 GO:0014842 regulation of skeletal muscle satellite cell proliferation(GO:0014842)
0.5 2.7 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.5 5.3 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.5 2.1 GO:0042494 detection of bacterial lipoprotein(GO:0042494)
0.5 3.6 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
0.5 2.1 GO:0048687 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
0.5 2.5 GO:0072675 osteoclast fusion(GO:0072675)
0.5 2.5 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.5 5.0 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.5 1.5 GO:0001543 ovarian follicle rupture(GO:0001543)
0.5 1.9 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.5 6.7 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.5 8.0 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.5 1.9 GO:0048539 bone marrow development(GO:0048539)
0.5 8.4 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.5 6.0 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.5 3.2 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.5 1.4 GO:0086100 endothelin receptor signaling pathway(GO:0086100)
0.5 1.4 GO:0021972 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) corticospinal neuron axon guidance through spinal cord(GO:0021972) regulation of negative chemotaxis(GO:0050923) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
0.5 1.4 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.4 1.8 GO:1903898 negative regulation of PERK-mediated unfolded protein response(GO:1903898)
0.4 2.6 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.4 2.6 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.4 11.7 GO:0017121 phospholipid scrambling(GO:0017121)
0.4 11.1 GO:0060216 definitive hemopoiesis(GO:0060216)
0.4 1.3 GO:0009624 response to nematode(GO:0009624)
0.4 4.2 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
0.4 9.2 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.4 2.1 GO:0031133 regulation of axon diameter(GO:0031133)
0.4 10.7 GO:0030220 platelet formation(GO:0030220)
0.4 1.2 GO:0051866 general adaptation syndrome(GO:0051866)
0.4 6.6 GO:0045161 neuronal ion channel clustering(GO:0045161)
0.4 1.2 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.4 4.8 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.4 6.9 GO:1901642 nucleoside transmembrane transport(GO:1901642)
0.4 1.1 GO:0060364 frontal suture morphogenesis(GO:0060364)
0.4 3.0 GO:0006527 arginine catabolic process(GO:0006527)
0.4 8.9 GO:0003417 growth plate cartilage development(GO:0003417)
0.4 3.3 GO:0019372 lipoxygenase pathway(GO:0019372)
0.4 8.8 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.4 9.1 GO:0051764 actin crosslink formation(GO:0051764)
0.4 1.4 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.4 11.2 GO:0019731 antibacterial humoral response(GO:0019731)
0.4 7.2 GO:0043968 histone H2A acetylation(GO:0043968)
0.4 2.9 GO:0006265 DNA topological change(GO:0006265) embryonic cleavage(GO:0040016)
0.4 21.0 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.4 6.7 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.3 1.4 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.3 2.0 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.3 1.0 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.3 1.0 GO:0045896 regulation of transcription during mitotic cell cycle(GO:0045896) positive regulation of transcription during mitotic cell cycle(GO:0045897) regulation of transcription from RNA polymerase II promoter during mitotic cell cycle(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitotic cell cycle(GO:0046022) axial mesoderm morphogenesis(GO:0048319)
0.3 1.3 GO:0008594 photoreceptor cell morphogenesis(GO:0008594)
0.3 3.9 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.3 0.6 GO:1990859 cellular response to endothelin(GO:1990859)
0.3 1.0 GO:0042560 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.3 1.6 GO:0021993 initiation of neural tube closure(GO:0021993)
0.3 1.3 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.3 3.5 GO:0045075 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.3 1.0 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.3 1.0 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.3 6.9 GO:0014823 response to activity(GO:0014823)
0.3 2.2 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.3 3.5 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.3 1.3 GO:0021586 pons maturation(GO:0021586)
0.3 3.3 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.3 10.9 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.3 3.1 GO:0086036 regulation of cardiac muscle cell membrane potential(GO:0086036)
0.3 0.6 GO:0003162 atrioventricular node development(GO:0003162)
0.3 2.3 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.3 3.3 GO:0048671 negative regulation of collateral sprouting(GO:0048671)
0.3 0.8 GO:0070429 regulation of granuloma formation(GO:0002631) negative regulation of granuloma formation(GO:0002632) regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433) tolerance induction to lipopolysaccharide(GO:0072573)
0.3 0.5 GO:2001015 negative regulation of skeletal muscle cell differentiation(GO:2001015)
0.3 0.8 GO:0042791 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) RNA polymerase III transcriptional preinitiation complex assembly(GO:0070898)
0.3 2.4 GO:2001197 regulation of basement membrane organization(GO:0110011) regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.3 2.9 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.3 0.3 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593)
0.3 1.6 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.3 0.8 GO:0033189 response to vitamin A(GO:0033189)
0.3 1.8 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.3 0.8 GO:0015827 tryptophan transport(GO:0015827)
0.3 2.3 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.3 2.0 GO:0040009 regulation of growth rate(GO:0040009)
0.2 0.7 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.2 3.2 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.2 1.0 GO:0046984 regulation of hemoglobin biosynthetic process(GO:0046984)
0.2 1.0 GO:0060709 glycogen cell differentiation involved in embryonic placenta development(GO:0060709)
0.2 10.1 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.2 7.4 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.2 2.6 GO:0033623 regulation of integrin activation(GO:0033623)
0.2 1.0 GO:0051684 maintenance of Golgi location(GO:0051684)
0.2 0.9 GO:2000973 regulation of pro-B cell differentiation(GO:2000973)
0.2 1.6 GO:0051013 microtubule severing(GO:0051013)
0.2 0.9 GO:0031509 telomeric heterochromatin assembly(GO:0031509)
0.2 0.7 GO:1901656 glycoside transport(GO:1901656)
0.2 3.2 GO:0046036 CTP biosynthetic process(GO:0006241) CTP metabolic process(GO:0046036)
0.2 0.9 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.2 2.7 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.2 4.4 GO:0007289 spermatid nucleus differentiation(GO:0007289)
0.2 1.8 GO:2000737 negative regulation of stem cell differentiation(GO:2000737)
0.2 2.2 GO:0032486 Rap protein signal transduction(GO:0032486)
0.2 1.5 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.2 1.3 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.2 0.6 GO:0007262 STAT protein import into nucleus(GO:0007262) establishment of synaptic specificity at neuromuscular junction(GO:0007529) regulation of renin secretion into blood stream(GO:1900133)
0.2 17.6 GO:0051225 spindle assembly(GO:0051225)
0.2 5.8 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.2 0.6 GO:0002304 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.2 0.8 GO:0061857 endoplasmic reticulum stress-induced pre-emptive quality control(GO:0061857)
0.2 3.9 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.2 3.7 GO:0046069 cGMP catabolic process(GO:0046069)
0.2 1.0 GO:0033227 dsRNA transport(GO:0033227)
0.2 3.2 GO:0038092 nodal signaling pathway(GO:0038092)
0.2 1.6 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.2 4.9 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.2 1.8 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.2 4.7 GO:0048148 behavioral response to cocaine(GO:0048148)
0.2 1.2 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.2 7.7 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.2 0.8 GO:0048496 maintenance of animal organ identity(GO:0048496)
0.2 1.9 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.2 8.0 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.2 0.7 GO:0019509 L-methionine salvage from methylthioadenosine(GO:0019509)
0.2 1.7 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.2 1.8 GO:0045625 regulation of T-helper 1 cell differentiation(GO:0045625)
0.2 3.6 GO:0030574 collagen catabolic process(GO:0030574)
0.2 0.9 GO:0060279 positive regulation of ovulation(GO:0060279)
0.2 2.7 GO:0033008 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.2 0.9 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.2 1.4 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.2 3.4 GO:0021535 cell migration in hindbrain(GO:0021535)
0.2 1.6 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.2 0.4 GO:1905664 regulation of calcium ion import across plasma membrane(GO:1905664)
0.2 1.4 GO:0046831 regulation of RNA export from nucleus(GO:0046831)
0.2 0.4 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726)
0.2 1.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.2 2.0 GO:0031507 heterochromatin assembly(GO:0031507)
0.2 2.1 GO:0006020 inositol metabolic process(GO:0006020)
0.2 0.5 GO:0021698 cerebellar cortex structural organization(GO:0021698)
0.2 5.0 GO:0034724 DNA replication-independent nucleosome organization(GO:0034724)
0.2 1.9 GO:0070269 pyroptosis(GO:0070269)
0.2 4.2 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.2 0.7 GO:0002370 natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727)
0.2 0.7 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.2 1.0 GO:0009136 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.2 6.0 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.2 0.8 GO:0032226 positive regulation of synaptic transmission, dopaminergic(GO:0032226)
0.2 1.0 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.2 1.9 GO:0071280 cellular response to copper ion(GO:0071280)
0.2 0.6 GO:0072718 response to cisplatin(GO:0072718)
0.2 7.5 GO:0030042 actin filament depolymerization(GO:0030042)
0.2 3.6 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.1 0.9 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.1 5.2 GO:1901381 positive regulation of potassium ion transmembrane transport(GO:1901381)
0.1 3.2 GO:0034377 plasma lipoprotein particle assembly(GO:0034377)
0.1 0.9 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.1 0.3 GO:0036216 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.1 1.7 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 4.8 GO:0031648 protein destabilization(GO:0031648)
0.1 1.4 GO:0001553 luteinization(GO:0001553)
0.1 3.0 GO:0050832 defense response to fungus(GO:0050832)
0.1 2.8 GO:0010714 positive regulation of collagen metabolic process(GO:0010714) positive regulation of collagen biosynthetic process(GO:0032967) positive regulation of multicellular organismal metabolic process(GO:0044253)
0.1 0.1 GO:0042275 error-free postreplication DNA repair(GO:0042275)
0.1 1.6 GO:0032274 gonadotropin secretion(GO:0032274)
0.1 2.8 GO:0008209 androgen metabolic process(GO:0008209)
0.1 1.2 GO:0010771 negative regulation of cell morphogenesis involved in differentiation(GO:0010771)
0.1 1.2 GO:0030538 hindgut morphogenesis(GO:0007442) embryonic genitalia morphogenesis(GO:0030538) embryonic hindgut morphogenesis(GO:0048619)
0.1 1.1 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.1 0.7 GO:2000173 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716) negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.1 1.2 GO:0032570 response to progesterone(GO:0032570)
0.1 1.6 GO:0038171 cannabinoid signaling pathway(GO:0038171)
0.1 0.4 GO:0009256 10-formyltetrahydrofolate metabolic process(GO:0009256)
0.1 0.9 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 0.8 GO:0098903 regulation of membrane repolarization during action potential(GO:0098903)
0.1 1.1 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.1 0.4 GO:0046666 retinal cell programmed cell death(GO:0046666)
0.1 2.3 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.1 1.0 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 2.7 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.1 1.2 GO:0014807 regulation of somitogenesis(GO:0014807)
0.1 3.1 GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.1 2.5 GO:0045760 positive regulation of action potential(GO:0045760)
0.1 0.3 GO:2001046 positive regulation of integrin-mediated signaling pathway(GO:2001046)
0.1 0.3 GO:0048239 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.1 1.7 GO:0042415 norepinephrine metabolic process(GO:0042415)
0.1 0.4 GO:0097298 regulation of nucleus size(GO:0097298)
0.1 10.2 GO:0051028 mRNA transport(GO:0051028)
0.1 4.0 GO:1902652 cholesterol metabolic process(GO:0008203) secondary alcohol metabolic process(GO:1902652)
0.1 1.1 GO:0006337 nucleosome disassembly(GO:0006337)
0.1 1.5 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.1 0.9 GO:0000729 DNA double-strand break processing(GO:0000729)
0.1 2.7 GO:0030517 negative regulation of axon extension(GO:0030517)
0.1 1.4 GO:0072673 lamellipodium morphogenesis(GO:0072673)
0.1 0.8 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.1 0.4 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 1.0 GO:0048520 positive regulation of behavior(GO:0048520)
0.1 1.5 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.1 10.7 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.1 0.3 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.1 0.4 GO:0060398 regulation of growth hormone receptor signaling pathway(GO:0060398)
0.1 1.1 GO:0050858 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1 1.0 GO:0046040 IMP metabolic process(GO:0046040)
0.1 0.4 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.1 0.5 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.1 0.5 GO:0090190 positive regulation of mesonephros development(GO:0061213) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.1 0.9 GO:0098664 serotonin receptor signaling pathway(GO:0007210) G-protein coupled serotonin receptor signaling pathway(GO:0098664)
0.1 3.3 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 0.2 GO:0010966 regulation of phosphate transport(GO:0010966)
0.1 1.4 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 1.8 GO:0060009 Sertoli cell development(GO:0060009)
0.1 0.7 GO:0015879 carnitine transport(GO:0015879)
0.1 0.2 GO:0140009 L-aspartate import across plasma membrane(GO:0140009) D-aspartate import across plasma membrane(GO:0140016)
0.1 14.4 GO:0008654 phospholipid biosynthetic process(GO:0008654)
0.1 2.9 GO:0015804 neutral amino acid transport(GO:0015804)
0.1 1.0 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.1 2.0 GO:0009299 mRNA transcription(GO:0009299)
0.1 4.4 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.1 1.3 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.1 0.1 GO:0072708 response to sorbitol(GO:0072708)
0.1 0.8 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.1 0.5 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 3.9 GO:0006334 nucleosome assembly(GO:0006334)
0.1 0.4 GO:0038007 anterior/posterior axon guidance(GO:0033564) netrin-activated signaling pathway(GO:0038007)
0.1 1.7 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.1 2.3 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.1 1.3 GO:0045739 positive regulation of DNA repair(GO:0045739)
0.1 5.5 GO:0010977 negative regulation of neuron projection development(GO:0010977)
0.1 1.2 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.1 0.5 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.1 2.3 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 5.0 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.1 1.3 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 2.0 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.1 0.6 GO:0035246 peptidyl-arginine N-methylation(GO:0035246)
0.1 0.5 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.1 1.9 GO:0009409 response to cold(GO:0009409)
0.1 0.3 GO:0060689 cell differentiation involved in salivary gland development(GO:0060689)
0.1 1.0 GO:0007019 microtubule depolymerization(GO:0007019)
0.1 3.6 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.1 0.2 GO:0106005 RNA 5'-cap (guanine-N7)-methylation(GO:0106005)
0.0 1.5 GO:0033344 cholesterol efflux(GO:0033344)
0.0 1.0 GO:0060065 uterus development(GO:0060065)
0.0 1.1 GO:1903427 negative regulation of reactive oxygen species biosynthetic process(GO:1903427)
0.0 0.3 GO:0060290 transdifferentiation(GO:0060290)
0.0 2.5 GO:0008584 male gonad development(GO:0008584) development of primary male sexual characteristics(GO:0046546)
0.0 0.6 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.1 GO:1903400 L-arginine transmembrane transport(GO:1903400)
0.0 1.1 GO:0045124 regulation of bone resorption(GO:0045124)
0.0 0.4 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 1.2 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.0 0.3 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.5 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.0 0.3 GO:0009301 snRNA transcription(GO:0009301)
0.0 1.3 GO:0048844 artery morphogenesis(GO:0048844)
0.0 0.9 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.3 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.0 0.6 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 3.9 GO:0007411 axon guidance(GO:0007411)
0.0 0.7 GO:0040018 positive regulation of multicellular organism growth(GO:0040018)
0.0 0.2 GO:0048712 negative regulation of astrocyte differentiation(GO:0048712)
0.0 3.5 GO:0006694 steroid biosynthetic process(GO:0006694)
0.0 0.8 GO:1904659 glucose transmembrane transport(GO:1904659)
0.0 1.0 GO:0007340 membrane fusion involved in acrosome reaction(GO:0002078) acrosome reaction(GO:0007340) acrosomal vesicle exocytosis(GO:0060478)
0.0 0.3 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.0 1.7 GO:0030168 platelet activation(GO:0030168)
0.0 1.3 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 0.1 GO:0048864 stem cell development(GO:0048864)
0.0 0.7 GO:0019236 response to pheromone(GO:0019236)
0.0 0.2 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.4 GO:2001240 negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.3 GO:0001967 suckling behavior(GO:0001967)
0.0 0.2 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 1.5 GO:0044070 regulation of anion transport(GO:0044070)
0.0 0.5 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.2 GO:0035767 endothelial cell chemotaxis(GO:0035767)
0.0 0.3 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.1 GO:0031053 primary miRNA processing(GO:0031053)
0.0 2.6 GO:0043588 skin development(GO:0043588)
0.0 0.2 GO:0046856 phospholipid dephosphorylation(GO:0046839) phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.4 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
10.7 32.0 GO:0033193 Lsd1/2 complex(GO:0033193)
9.8 29.5 GO:0071149 TEAD-2-YAP complex(GO:0071149)
3.0 11.8 GO:0008623 CHRAC(GO:0008623)
2.4 12.0 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
2.0 16.1 GO:0005833 hemoglobin complex(GO:0005833)
2.0 6.0 GO:0042585 germinal vesicle(GO:0042585)
1.9 13.5 GO:0019815 B cell receptor complex(GO:0019815)
1.8 10.6 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
1.7 7.0 GO:1902737 dendritic filopodium(GO:1902737)
1.6 4.9 GO:0005673 transcription factor TFIIE complex(GO:0005673)
1.5 7.4 GO:0071914 prominosome(GO:0071914)
1.3 6.6 GO:0036449 microtubule minus-end(GO:0036449)
1.2 5.0 GO:0044302 dentate gyrus mossy fiber(GO:0044302)
1.2 2.5 GO:0044393 microspike(GO:0044393)
1.2 9.5 GO:0033269 internode region of axon(GO:0033269)
1.2 26.5 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
1.1 2.3 GO:0033093 Weibel-Palade body(GO:0033093)
1.1 3.3 GO:0071148 TEAD-1-YAP complex(GO:0071148)
1.1 18.8 GO:0001527 microfibril(GO:0001527)
1.1 11.6 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
1.0 4.1 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
1.0 8.2 GO:0097165 nuclear stress granule(GO:0097165)
1.0 6.8 GO:0031933 telomeric heterochromatin(GO:0031933)
1.0 5.7 GO:1990356 sumoylated E2 ligase complex(GO:1990356)
0.9 9.1 GO:0044327 dendritic spine head(GO:0044327)
0.9 3.5 GO:0005594 collagen type IX trimer(GO:0005594)
0.9 1.7 GO:0005859 muscle myosin complex(GO:0005859)
0.8 5.9 GO:0099061 integral component of postsynaptic density membrane(GO:0099061) intrinsic component of postsynaptic density membrane(GO:0099146)
0.8 11.5 GO:0097512 cardiac myofibril(GO:0097512)
0.8 7.2 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.8 2.4 GO:0045180 basal cortex(GO:0045180)
0.8 2.3 GO:0031251 PAN complex(GO:0031251)
0.7 2.0 GO:1990047 spindle matrix(GO:1990047)
0.6 1.3 GO:1990812 growth cone filopodium(GO:1990812)
0.6 9.1 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.6 7.0 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.6 2.5 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.6 1.8 GO:0071953 elastic fiber(GO:0071953)
0.6 2.4 GO:0008537 proteasome activator complex(GO:0008537)
0.6 1.8 GO:0002944 cyclin K-CDK12 complex(GO:0002944)
0.6 1.7 GO:0005593 FACIT collagen trimer(GO:0005593) collagen type XII trimer(GO:0005595) anchoring collagen complex(GO:0030934)
0.6 8.1 GO:0097431 mitotic spindle pole(GO:0097431)
0.6 1.7 GO:0035101 FACT complex(GO:0035101)
0.5 3.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.5 8.3 GO:0042581 specific granule(GO:0042581)
0.5 3.6 GO:0005927 muscle tendon junction(GO:0005927)
0.5 8.1 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.5 7.5 GO:0005641 nuclear envelope lumen(GO:0005641)
0.5 1.5 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.5 8.1 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.5 2.9 GO:0001651 dense fibrillar component(GO:0001651)
0.5 3.2 GO:0005638 lamin filament(GO:0005638)
0.5 2.3 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.4 4.0 GO:0000137 Golgi cis cisterna(GO:0000137)
0.4 1.3 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.4 2.9 GO:0031094 platelet dense tubular network(GO:0031094)
0.4 7.8 GO:0032433 filopodium tip(GO:0032433)
0.4 2.4 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.4 2.4 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.4 3.4 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.4 2.6 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.4 7.0 GO:0016580 Sin3 complex(GO:0016580)
0.4 1.5 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.4 12.2 GO:0090544 BAF-type complex(GO:0090544)
0.4 2.8 GO:0070652 HAUS complex(GO:0070652)
0.3 3.8 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.3 5.5 GO:0030061 mitochondrial crista(GO:0030061)
0.3 2.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.3 3.4 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.3 5.4 GO:0031932 TORC2 complex(GO:0031932)
0.3 2.7 GO:0042382 paraspeckles(GO:0042382)
0.3 8.0 GO:0032982 myosin filament(GO:0032982)
0.3 18.0 GO:0042555 MCM complex(GO:0042555) MCM core complex(GO:0097373)
0.3 3.5 GO:0031258 lamellipodium membrane(GO:0031258)
0.3 0.9 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.3 1.8 GO:0097443 sorting endosome(GO:0097443)
0.3 9.4 GO:0031430 M band(GO:0031430)
0.3 5.6 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.3 0.8 GO:1990075 periciliary membrane compartment(GO:1990075)
0.3 6.9 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.2 4.0 GO:0030056 hemidesmosome(GO:0030056)
0.2 0.7 GO:0030905 retromer, tubulation complex(GO:0030905)
0.2 1.4 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.2 5.5 GO:0031519 PcG protein complex(GO:0031519)
0.2 0.7 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.2 7.9 GO:0000788 nuclear nucleosome(GO:0000788)
0.2 14.1 GO:0005871 kinesin complex(GO:0005871)
0.2 2.0 GO:0005677 chromatin silencing complex(GO:0005677)
0.2 2.4 GO:0034464 BBSome(GO:0034464)
0.2 1.3 GO:1990023 mitotic spindle midzone(GO:1990023)
0.2 12.3 GO:0072562 blood microparticle(GO:0072562)
0.2 1.2 GO:0044530 supraspliceosomal complex(GO:0044530)
0.2 4.2 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.2 35.9 GO:0005923 bicellular tight junction(GO:0005923)
0.2 11.0 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.2 20.9 GO:0016363 nuclear matrix(GO:0016363)
0.2 2.4 GO:1990635 proximal dendrite(GO:1990635)
0.2 0.6 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.2 1.3 GO:0070160 occluding junction(GO:0070160)
0.2 1.7 GO:0031080 nuclear pore outer ring(GO:0031080)
0.2 4.8 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.2 1.7 GO:0044294 dendritic growth cone(GO:0044294)
0.2 19.1 GO:0032993 protein-DNA complex(GO:0032993)
0.2 2.3 GO:0097542 ciliary tip(GO:0097542)
0.2 1.4 GO:0072687 meiotic spindle(GO:0072687)
0.2 10.5 GO:0042629 mast cell granule(GO:0042629)
0.2 9.4 GO:0032587 ruffle membrane(GO:0032587)
0.2 0.6 GO:0070022 transforming growth factor beta receptor complex(GO:0070022)
0.2 2.9 GO:0042599 lamellar body(GO:0042599)
0.1 0.3 GO:0005608 laminin-3 complex(GO:0005608)
0.1 2.3 GO:0034719 SMN complex(GO:0032797) SMN-Sm protein complex(GO:0034719)
0.1 16.5 GO:0000932 P-body(GO:0000932)
0.1 3.8 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 0.6 GO:0099569 presynaptic cytoskeleton(GO:0099569)
0.1 4.5 GO:0045095 keratin filament(GO:0045095)
0.1 0.5 GO:0044307 dendritic branch(GO:0044307)
0.1 1.2 GO:0097524 sperm plasma membrane(GO:0097524)
0.1 7.8 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 6.0 GO:1904115 axon cytoplasm(GO:1904115)
0.1 1.4 GO:0005642 annulate lamellae(GO:0005642)
0.1 2.2 GO:0060076 excitatory synapse(GO:0060076)
0.1 1.1 GO:0043195 terminal bouton(GO:0043195)
0.1 0.8 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1 0.7 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1 0.8 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.1 0.7 GO:0098936 intrinsic component of postsynaptic membrane(GO:0098936) integral component of postsynaptic membrane(GO:0099055) intrinsic component of synaptic membrane(GO:0099240) integral component of synaptic membrane(GO:0099699)
0.1 1.0 GO:0000812 Swr1 complex(GO:0000812)
0.1 1.3 GO:0005861 troponin complex(GO:0005861)
0.1 0.5 GO:0002079 inner acrosomal membrane(GO:0002079)
0.1 4.1 GO:0005876 spindle microtubule(GO:0005876)
0.1 2.2 GO:0045177 apical part of cell(GO:0045177)
0.1 23.9 GO:0031965 nuclear membrane(GO:0031965)
0.1 2.9 GO:0005921 gap junction(GO:0005921)
0.1 5.2 GO:0031941 filamentous actin(GO:0031941)
0.1 2.3 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 6.4 GO:0099086 synaptonemal complex(GO:0000795) synaptonemal structure(GO:0099086)
0.1 0.4 GO:0001652 granular component(GO:0001652)
0.1 4.9 GO:0005720 nuclear heterochromatin(GO:0005720)
0.1 0.8 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.1 0.8 GO:0002177 manchette(GO:0002177)
0.1 0.4 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.1 6.6 GO:0005901 caveola(GO:0005901)
0.1 1.2 GO:0005776 autophagosome(GO:0005776)
0.1 5.4 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 3.2 GO:0030315 T-tubule(GO:0030315)
0.1 5.0 GO:0043198 dendritic shaft(GO:0043198)
0.1 0.7 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 11.3 GO:0030027 lamellipodium(GO:0030027)
0.1 2.0 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 0.5 GO:0000813 ESCRT I complex(GO:0000813)
0.1 0.5 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 0.4 GO:0000125 PCAF complex(GO:0000125)
0.1 3.6 GO:0005882 intermediate filament(GO:0005882)
0.1 2.2 GO:0000792 heterochromatin(GO:0000792)
0.1 4.5 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 0.4 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 0.5 GO:0070545 PeBoW complex(GO:0070545)
0.1 1.6 GO:1990391 DNA repair complex(GO:1990391)
0.0 3.8 GO:0000922 spindle pole(GO:0000922)
0.0 1.1 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 0.7 GO:0097526 spliceosomal tri-snRNP complex(GO:0097526)
0.0 2.3 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.7 GO:0031528 microvillus membrane(GO:0031528)
0.0 3.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.7 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 1.2 GO:0005685 U1 snRNP(GO:0005685)
0.0 7.3 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 1.7 GO:0001772 immunological synapse(GO:0001772)
0.0 0.6 GO:0036379 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.0 1.6 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.4 GO:0036038 MKS complex(GO:0036038)
0.0 2.6 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.4 GO:0031672 A band(GO:0031672)
0.0 0.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 1.3 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 0.1 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.0 0.8 GO:0043235 receptor complex(GO:0043235)
0.0 0.8 GO:0032040 small-subunit processome(GO:0032040)
0.0 4.3 GO:0001650 fibrillar center(GO:0001650)
0.0 0.4 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.7 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.1 GO:1990752 microtubule plus-end(GO:0035371) microtubule end(GO:1990752)
0.0 0.9 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.1 GO:1903095 microprocessor complex(GO:0070877) ribonuclease III complex(GO:1903095)
0.0 2.2 GO:0097540 sperm flagellum(GO:0036126) axonemal central pair(GO:0097540) axonemal outer doublet(GO:0097545) A axonemal microtubule(GO:0097649) B axonemal microtubule(GO:0097650) 9+2 motile cilium(GO:0097729) C1 axonemal microtubule(GO:1990719) C2 axonemal microtubule(GO:1990720)
0.0 1.4 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 3.1 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.8 GO:0016592 mediator complex(GO:0016592) core mediator complex(GO:0070847)
0.0 3.7 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.3 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.1 GO:0005686 U2-type spliceosomal complex(GO:0005684) U2 snRNP(GO:0005686)
0.0 0.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834) GTPase complex(GO:1905360)
0.0 0.6 GO:0031514 motile cilium(GO:0031514)
0.0 0.8 GO:0005769 early endosome(GO:0005769)
0.0 0.1 GO:0016012 dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.0 0.1 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 2.3 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 1.0 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.7 GO:0043204 perikaryon(GO:0043204)
0.0 3.9 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.8 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.9 14.8 GO:0046592 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
3.0 24.4 GO:0004769 steroid delta-isomerase activity(GO:0004769)
2.9 14.3 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
2.6 10.3 GO:0031721 hemoglobin alpha binding(GO:0031721)
2.4 9.6 GO:0038025 reelin receptor activity(GO:0038025)
2.4 12.0 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
2.3 9.1 GO:0071987 WD40-repeat domain binding(GO:0071987)
2.2 11.0 GO:0070051 fibrinogen binding(GO:0070051)
2.1 15.0 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
2.1 6.4 GO:0017084 glutamate 5-kinase activity(GO:0004349) glutamate-5-semialdehyde dehydrogenase activity(GO:0004350) delta1-pyrroline-5-carboxylate synthetase activity(GO:0017084) amino acid kinase activity(GO:0019202)
2.0 6.1 GO:1905576 ganglioside GT1b binding(GO:1905576)
1.7 33.7 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
1.7 6.7 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
1.6 6.3 GO:0004945 angiotensin type II receptor activity(GO:0004945)
1.5 9.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
1.5 19.7 GO:0005522 profilin binding(GO:0005522)
1.4 11.6 GO:0004687 myosin light chain kinase activity(GO:0004687)
1.4 7.1 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
1.4 4.1 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
1.3 10.7 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
1.3 21.2 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
1.3 16.9 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
1.3 2.5 GO:0034046 poly(G) binding(GO:0034046)
1.2 7.3 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
1.2 4.8 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
1.1 4.6 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
1.1 4.6 GO:0086077 gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
1.1 18.2 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
1.1 3.4 GO:0097677 STAT family protein binding(GO:0097677)
1.1 6.6 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
1.1 4.3 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
1.1 3.3 GO:0046969 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
1.1 4.3 GO:0004832 valine-tRNA ligase activity(GO:0004832)
1.0 5.9 GO:0005344 oxygen transporter activity(GO:0005344)
1.0 5.7 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.9 8.4 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.9 7.2 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.9 3.6 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.9 9.0 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.8 2.5 GO:0004461 lactose synthase activity(GO:0004461)
0.8 3.2 GO:0003883 CTP synthase activity(GO:0003883)
0.8 4.7 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.8 5.3 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.7 3.7 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.7 5.9 GO:0004064 arylesterase activity(GO:0004064)
0.7 2.9 GO:0050436 microfibril binding(GO:0050436)
0.7 3.6 GO:0030621 U4 snRNA binding(GO:0030621)
0.7 2.9 GO:0097100 supercoiled DNA binding(GO:0097100)
0.7 2.1 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.7 7.0 GO:0051434 BH3 domain binding(GO:0051434)
0.7 9.0 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.7 2.1 GO:0000402 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
0.7 2.8 GO:0030284 estrogen receptor activity(GO:0030284)
0.7 2.7 GO:1990254 keratin filament binding(GO:1990254)
0.7 2.7 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.7 7.8 GO:0030274 LIM domain binding(GO:0030274)
0.6 36.8 GO:0070888 E-box binding(GO:0070888)
0.6 1.9 GO:0030226 aminophospholipid transporter activity(GO:0015247) apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.6 1.8 GO:0042015 interleukin-20 binding(GO:0042015)
0.6 5.4 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.6 5.4 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.6 1.7 GO:0033680 ATP-dependent DNA/RNA helicase activity(GO:0033680)
0.6 2.3 GO:0035851 histone deacetylase activity (H4-K16 specific)(GO:0034739) Krueppel-associated box domain binding(GO:0035851)
0.6 2.8 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.6 2.8 GO:0015616 DNA translocase activity(GO:0015616)
0.6 5.5 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.6 0.6 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.6 3.3 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.6 3.9 GO:0031013 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.6 5.0 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.5 17.4 GO:0008187 poly-pyrimidine tract binding(GO:0008187)
0.5 3.7 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.5 6.7 GO:0031432 titin binding(GO:0031432)
0.5 5.0 GO:0004716 signal transducer, downstream of receptor, with protein tyrosine kinase activity(GO:0004716)
0.5 7.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.5 2.0 GO:0003884 D-amino-acid oxidase activity(GO:0003884)
0.5 3.4 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229) intracellular chloride channel activity(GO:0061778)
0.5 2.9 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.5 4.2 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.5 2.8 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.5 16.1 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.5 1.4 GO:0004962 endothelin receptor activity(GO:0004962)
0.4 3.1 GO:0034056 estrogen response element binding(GO:0034056)
0.4 7.1 GO:0005523 tropomyosin binding(GO:0005523)
0.4 1.3 GO:0032190 acrosin binding(GO:0032190)
0.4 1.3 GO:0005119 smoothened binding(GO:0005119)
0.4 11.7 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.4 10.7 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.4 1.7 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.4 4.2 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.4 0.4 GO:0042054 histone methyltransferase activity(GO:0042054)
0.4 2.1 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.4 16.0 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.4 2.1 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.4 2.9 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.4 1.2 GO:0071633 dihydroceramidase activity(GO:0071633)
0.4 1.6 GO:0099103 channel activator activity(GO:0099103) potassium channel activator activity(GO:0099104)
0.4 3.5 GO:0008865 fructokinase activity(GO:0008865)
0.4 3.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.4 2.3 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.4 15.0 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.4 8.5 GO:0017049 GTP-Rho binding(GO:0017049)
0.4 1.5 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.4 2.7 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.4 1.8 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.4 3.2 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.4 3.2 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.4 3.9 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.4 7.1 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.4 4.2 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.4 0.7 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.3 4.8 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.3 7.0 GO:0005212 structural constituent of eye lens(GO:0005212)
0.3 2.0 GO:0004111 creatine kinase activity(GO:0004111)
0.3 1.0 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.3 3.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.3 1.6 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.3 1.3 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.3 1.9 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.3 3.6 GO:0070492 oligosaccharide binding(GO:0070492)
0.3 12.6 GO:0003785 actin monomer binding(GO:0003785)
0.3 2.1 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931)
0.3 1.5 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.3 1.8 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.3 9.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.3 6.8 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.3 2.2 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.3 1.4 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.3 0.8 GO:0070052 collagen V binding(GO:0070052)
0.3 2.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.3 2.4 GO:0061133 endopeptidase activator activity(GO:0061133)
0.3 6.0 GO:0042288 MHC class I protein binding(GO:0042288)
0.3 2.8 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.3 2.1 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004) neurotrophin receptor activity(GO:0005030)
0.3 6.2 GO:0070064 proline-rich region binding(GO:0070064)
0.2 3.7 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.2 0.2 GO:0015116 secondary active sulfate transmembrane transporter activity(GO:0008271) sulfate transmembrane transporter activity(GO:0015116)
0.2 1.7 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.2 1.2 GO:0005415 nucleoside:sodium symporter activity(GO:0005415)
0.2 3.6 GO:0003680 AT DNA binding(GO:0003680)
0.2 3.1 GO:0001163 RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.2 1.0 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.2 1.9 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.2 2.8 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.2 1.4 GO:0034452 dynactin binding(GO:0034452)
0.2 7.7 GO:0017091 AU-rich element binding(GO:0017091)
0.2 10.6 GO:0017080 sodium channel regulator activity(GO:0017080)
0.2 7.2 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.2 3.9 GO:0030215 semaphorin receptor binding(GO:0030215)
0.2 6.5 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.2 5.1 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.2 2.7 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.2 1.9 GO:0008131 primary amine oxidase activity(GO:0008131)
0.2 1.9 GO:0051011 microtubule minus-end binding(GO:0051011)
0.2 15.6 GO:0005518 collagen binding(GO:0005518)
0.2 9.1 GO:0046875 ephrin receptor binding(GO:0046875)
0.2 2.4 GO:0045499 chemorepellent activity(GO:0045499)
0.2 2.2 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.2 1.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.2 4.7 GO:0019789 SUMO transferase activity(GO:0019789)
0.2 1.3 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.2 0.7 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.2 4.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.2 0.7 GO:1990460 leptin receptor binding(GO:1990460)
0.2 0.7 GO:0004952 dopamine neurotransmitter receptor activity(GO:0004952)
0.2 1.4 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.2 7.7 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.2 1.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.2 0.3 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.2 1.5 GO:1990446 U1 snRNP binding(GO:1990446)
0.2 3.3 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.2 10.7 GO:0019843 rRNA binding(GO:0019843)
0.2 1.2 GO:0045322 unmethylated CpG binding(GO:0045322)
0.2 8.0 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.2 3.1 GO:0008179 adenylate cyclase binding(GO:0008179)
0.2 10.3 GO:0097110 scaffold protein binding(GO:0097110)
0.2 3.2 GO:0004935 adrenergic receptor activity(GO:0004935)
0.2 1.8 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.2 2.1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.2 0.9 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.2 6.1 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.2 4.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.2 0.8 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.1 2.4 GO:0015643 toxic substance binding(GO:0015643)
0.1 1.6 GO:0046790 virion binding(GO:0046790)
0.1 2.7 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 9.7 GO:0030507 spectrin binding(GO:0030507)
0.1 7.6 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 7.6 GO:0042805 actinin binding(GO:0042805)
0.1 14.9 GO:0003777 microtubule motor activity(GO:0003777)
0.1 4.6 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 2.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 0.4 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.1 1.7 GO:0140034 methylated histone binding(GO:0035064) methylation-dependent protein binding(GO:0140034)
0.1 1.6 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.1 0.4 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.1 1.0 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.1 2.0 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.1 4.2 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.1 2.2 GO:0001618 virus receptor activity(GO:0001618)
0.1 1.6 GO:0003678 DNA helicase activity(GO:0003678)
0.1 1.0 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.1 0.7 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.1 1.4 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.1 0.7 GO:0005124 scavenger receptor binding(GO:0005124)
0.1 0.6 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.1 0.8 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 6.7 GO:0048365 Rac GTPase binding(GO:0048365)
0.1 3.3 GO:0031491 nucleosome binding(GO:0031491)
0.1 1.4 GO:0070412 R-SMAD binding(GO:0070412)
0.1 1.3 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.1 0.7 GO:0031005 filamin binding(GO:0031005)
0.1 1.3 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 9.9 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1 0.9 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.1 12.2 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.1 1.0 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 0.6 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.1 4.1 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 0.9 GO:0102991 myristoyl-CoA hydrolase activity(GO:0102991)
0.1 2.6 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 13.3 GO:0051015 actin filament binding(GO:0051015)
0.1 0.9 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 1.4 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 0.3 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.7 GO:0050700 CARD domain binding(GO:0050700)
0.1 1.4 GO:0070840 dynein complex binding(GO:0070840)
0.1 2.8 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 0.4 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 0.6 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 4.8 GO:0003774 motor activity(GO:0003774)
0.1 1.2 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 7.0 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.1 2.6 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 0.4 GO:0005042 netrin receptor activity(GO:0005042)
0.1 0.3 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1 2.6 GO:0042169 SH2 domain binding(GO:0042169)
0.1 0.5 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.1 13.2 GO:0003779 actin binding(GO:0003779)
0.1 0.6 GO:0016274 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.1 0.4 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 0.6 GO:0050733 RS domain binding(GO:0050733)
0.1 2.9 GO:0030674 protein binding, bridging(GO:0030674)
0.1 0.8 GO:0016918 retinal binding(GO:0016918)
0.1 0.6 GO:1990459 transferrin receptor binding(GO:1990459)
0.1 0.8 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 2.0 GO:0001221 transcription cofactor binding(GO:0001221)
0.1 6.2 GO:0005179 hormone activity(GO:0005179)
0.1 0.3 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
0.1 0.8 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.1 0.2 GO:0004482 mRNA (guanine-N7-)-methyltransferase activity(GO:0004482)
0.1 1.0 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 1.0 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.9 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 1.9 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.2 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 2.1 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.6 GO:0070577 lysine-acetylated histone binding(GO:0070577) acetylation-dependent protein binding(GO:0140033)
0.0 6.9 GO:0008301 DNA binding, bending(GO:0008301)
0.0 2.3 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.4 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 1.3 GO:0008483 transaminase activity(GO:0008483)
0.0 0.6 GO:0016493 C-C chemokine receptor activity(GO:0016493) C-C chemokine binding(GO:0019957)
0.0 1.1 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 1.0 GO:0071837 HMG box domain binding(GO:0071837)
0.0 3.6 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.1 GO:0034211 GTP-dependent protein kinase activity(GO:0034211)
0.0 0.3 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.8 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 1.2 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.8 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.5 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.5 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 1.1 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.8 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.0 7.4 GO:0045296 cadherin binding(GO:0045296)
0.0 0.3 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 3.6 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.9 GO:0003954 NADH dehydrogenase activity(GO:0003954)
0.0 0.4 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.4 GO:0046527 glucosyltransferase activity(GO:0046527)
0.0 4.6 GO:0003729 mRNA binding(GO:0003729)
0.0 0.1 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 1.6 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.7 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 0.2 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 1.3 GO:0003682 chromatin binding(GO:0003682)
0.0 3.5 GO:0008201 heparin binding(GO:0008201)
0.0 0.1 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.1 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
0.0 0.6 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.2 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 1.0 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.1 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0 0.1 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 5.4 GO:0005198 structural molecule activity(GO:0005198)
0.0 0.4 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 0.2 GO:0004622 lysophospholipase activity(GO:0004622)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 15.4 PID_S1P_META_PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.5 30.7 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.5 7.2 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.4 8.2 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.4 17.3 PID_ATR_PATHWAY ATR signaling pathway
0.4 6.7 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.4 9.1 PID_IL2_PI3K_PATHWAY IL2 signaling events mediated by PI3K
0.4 21.9 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.3 4.5 PID_EPHA2_FWD_PATHWAY EPHA2 forward signaling
0.3 14.5 PID_PLK1_PATHWAY PLK1 signaling events
0.3 23.0 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.3 10.0 PID_EPHB_FWD_PATHWAY EPHB forward signaling
0.3 5.0 PID_NFKAPPAB_ATYPICAL_PATHWAY Atypical NF-kappaB pathway
0.3 3.4 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.2 11.3 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.2 21.0 PID_NOTCH_PATHWAY Notch signaling pathway
0.2 7.1 PID_LKB1_PATHWAY LKB1 signaling events
0.2 1.2 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.2 12.4 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.2 9.9 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.2 7.1 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction
0.2 3.4 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.2 5.9 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.2 3.7 PID_ER_NONGENOMIC_PATHWAY Plasma membrane estrogen receptor signaling
0.2 3.7 PID_P38_ALPHA_BETA_PATHWAY Regulation of p38-alpha and p38-beta
0.2 8.6 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.2 4.1 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.2 3.1 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.2 5.0 PID_FAK_PATHWAY Signaling events mediated by focal adhesion kinase
0.2 5.1 PID_SHP2_PATHWAY SHP2 signaling
0.2 0.8 PID_RETINOIC_ACID_PATHWAY Retinoic acid receptors-mediated signaling
0.2 2.3 PID_MYC_PATHWAY C-MYC pathway
0.1 5.2 ST_P38_MAPK_PATHWAY p38 MAPK Pathway
0.1 0.9 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 1.4 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.1 1.8 PID_IL27_PATHWAY IL27-mediated signaling events
0.1 1.3 PID_ANTHRAX_PATHWAY Cellular roles of Anthrax toxin
0.1 4.9 PID_BCR_5PATHWAY BCR signaling pathway
0.1 5.3 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.1 3.6 ST_TUMOR_NECROSIS_FACTOR_PATHWAY Tumor Necrosis Factor Pathway.
0.1 6.5 PID_E2F_PATHWAY E2F transcription factor network
0.1 0.9 SIG_IL4RECEPTOR_IN_B_LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.1 9.8 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 2.8 PID_MET_PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1 5.0 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I
0.1 4.2 PID_CDC42_PATHWAY CDC42 signaling events
0.1 2.2 PID_ERBB4_PATHWAY ErbB4 signaling events
0.1 0.8 ST_PAC1_RECEPTOR_PATHWAY PAC1 Receptor Pathway
0.1 2.6 PID_LYSOPHOSPHOLIPID_PATHWAY LPA receptor mediated events
0.1 4.2 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.1 2.8 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 2.7 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.1 1.4 PID_AMB2_NEUTROPHILS_PATHWAY amb2 Integrin signaling
0.1 3.5 PID_P75_NTR_PATHWAY p75(NTR)-mediated signaling
0.1 1.2 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.1 1.7 PID_REELIN_PATHWAY Reelin signaling pathway
0.1 0.8 ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.1 1.1 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.1 1.4 PID_ENDOTHELIN_PATHWAY Endothelins
0.1 2.8 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 0.6 PID_THROMBIN_PAR1_PATHWAY PAR1-mediated thrombin signaling events
0.1 2.4 PID_P53_REGULATION_PATHWAY p53 pathway
0.1 2.3 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network
0.0 0.5 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.0 0.7 PID_IL4_2PATHWAY IL4-mediated signaling events
0.0 0.3 PID_SYNDECAN_2_PATHWAY Syndecan-2-mediated signaling events
0.0 1.0 PID_AURORA_B_PATHWAY Aurora B signaling
0.0 0.5 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 1.1 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.2 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.0 0.9 PID_MTOR_4PATHWAY mTOR signaling pathway
0.0 1.7 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.0 5.0 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.3 PID_ERBB2_ERBB3_PATHWAY ErbB2/ErbB3 signaling events
0.0 0.7 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.9 PID_CMYB_PATHWAY C-MYB transcription factor network
0.0 0.2 PID_RHOA_PATHWAY RhoA signaling pathway
0.0 0.6 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.0 0.6 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.3 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 24.4 REACTOME_ANDROGEN_BIOSYNTHESIS Genes involved in Androgen biosynthesis
1.2 19.7 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
1.0 7.0 REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX Genes involved in CDC6 association with the ORC:origin complex
1.0 16.6 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.9 18.5 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.7 7.8 REACTOME_ENDOGENOUS_STEROLS Genes involved in Endogenous sterols
0.7 13.6 REACTOME_INFLAMMASOMES Genes involved in Inflammasomes
0.7 11.5 REACTOME_HYALURONAN_METABOLISM Genes involved in Hyaluronan metabolism
0.7 12.0 REACTOME_G1_S_SPECIFIC_TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.6 19.7 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.6 24.5 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.6 11.3 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.5 6.0 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.5 10.0 REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.5 12.2 REACTOME_KINESINS Genes involved in Kinesins
0.4 3.7 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.4 12.2 REACTOME_REGULATION_OF_SIGNALING_BY_CBL Genes involved in Regulation of signaling by CBL
0.4 16.7 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.4 17.5 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.4 15.4 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.3 8.0 REACTOME_PLATELET_SENSITIZATION_BY_LDL Genes involved in Platelet sensitization by LDL
0.3 13.4 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.3 9.0 REACTOME_ACYL_CHAIN_REMODELLING_OF_PC Genes involved in Acyl chain remodelling of PC
0.3 1.0 REACTOME_CHONDROITIN_SULFATE_DERMATAN_SULFATE_METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.3 14.4 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.3 3.3 REACTOME_DEFENSINS Genes involved in Defensins
0.3 6.3 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.3 25.1 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.3 5.4 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.3 11.3 REACTOME_G1_PHASE Genes involved in G1 Phase
0.3 9.3 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.3 28.2 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.3 4.8 REACTOME_INTEGRIN_ALPHAIIB_BETA3_SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.3 3.4 REACTOME_REGULATION_OF_KIT_SIGNALING Genes involved in Regulation of KIT signaling
0.3 5.5 REACTOME_RNA_POL_III_CHAIN_ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.3 3.6 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.2 1.5 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.2 13.5 REACTOME_CIRCADIAN_CLOCK Genes involved in Circadian Clock
0.2 6.6 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION_IN_THE_MEDIAL_TRANS_GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.2 7.1 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.2 10.0 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.2 2.3 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
0.2 6.6 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.2 5.0 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.2 4.9 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.2 3.5 REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1 7.3 REACTOME_CLEAVAGE_OF_GROWING_TRANSCRIPT_IN_THE_TERMINATION_REGION_ Genes involved in Cleavage of Growing Transcript in the Termination Region
0.1 6.3 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 12.3 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT_ATP_SYNTHESIS_BY_CHEMIOSMOTIC_COUPLING_AND_HEAT_PRODUCTION_BY_UNCOUPLING_PROTEINS_ Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.1 2.1 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 6.9 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.1 13.0 REACTOME_LATE_PHASE_OF_HIV_LIFE_CYCLE Genes involved in Late Phase of HIV Life Cycle
0.1 5.0 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.1 1.9 REACTOME_IL_RECEPTOR_SHC_SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 3.3 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.1 1.6 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 0.8 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_2_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.1 2.6 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 2.9 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 0.8 REACTOME_NITRIC_OXIDE_STIMULATES_GUANYLATE_CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.1 4.0 REACTOME_SPHINGOLIPID_METABOLISM Genes involved in Sphingolipid metabolism
0.1 7.5 REACTOME_MRNA_SPLICING Genes involved in mRNA Splicing
0.1 0.6 REACTOME_SIGNALING_BY_FGFR Genes involved in Signaling by FGFR
0.1 5.3 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.1 2.0 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.1 5.5 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.1 1.0 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM Genes involved in Abacavir transport and metabolism
0.1 9.8 REACTOME_DIABETES_PATHWAYS Genes involved in Diabetes pathways
0.1 1.2 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.1 1.3 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 1.9 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 10.7 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 1.4 REACTOME_PYRUVATE_METABOLISM Genes involved in Pyruvate metabolism
0.1 0.9 REACTOME_METABOLISM_OF_NON_CODING_RNA Genes involved in Metabolism of non-coding RNA
0.1 3.0 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 1.6 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 0.4 REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.9 REACTOME_CONVERSION_FROM_APC_C_CDC20_TO_APC_C_CDH1_IN_LATE_ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 2.0 REACTOME_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL Genes involved in Cell surface interactions at the vascular wall
0.0 0.3 REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.3 REACTOME_P38MAPK_EVENTS Genes involved in p38MAPK events
0.0 1.4 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 1.1 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.0 1.5 REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY Genes involved in Costimulation by the CD28 family
0.0 4.1 REACTOME_MEIOSIS Genes involved in Meiosis
0.0 2.8 REACTOME_SIGNALING_BY_PDGF Genes involved in Signaling by PDGF
0.0 0.7 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 6.4 REACTOME_TRANSLATION Genes involved in Translation
0.0 0.5 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 1.0 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.8 REACTOME_NOD1_2_SIGNALING_PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.6 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.0 1.3 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.4 REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS Genes involved in G alpha (z) signalling events
0.0 0.1 REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.2 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.3 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.6 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.1 REACTOME_MICRORNA_MIRNA_BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis