Motif ID: Stat2

Z-value: 1.376


Transcription factors associated with Stat2:

Gene SymbolEntrez IDGene Name
Stat2 ENSMUSG00000040033.9 Stat2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Stat2mm10_v2_chr10_+_128270546_1282705770.711.0e-06Click!


Activity profile for motif Stat2.

activity profile for motif Stat2


Sorted Z-values histogram for motif Stat2

Sorted Z-values for motif Stat2



Network of associatons between targets according to the STRING database.



First level regulatory network of Stat2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_+_77729091 12.268 ENSMUST00000109775.2
Apol9b
apolipoprotein L 9b
chr6_+_41521782 9.314 ENSMUST00000070380.4
Prss2
protease, serine, 2
chr15_-_77411034 8.033 ENSMUST00000089452.5
ENSMUST00000081776.3
Apol9a

apolipoprotein L 9a

chr7_-_141010759 7.495 ENSMUST00000026565.6
Ifitm3
interferon induced transmembrane protein 3
chr1_+_130826762 6.942 ENSMUST00000133792.1
Pigr
polymeric immunoglobulin receptor
chr1_+_130826676 6.609 ENSMUST00000027675.7
Pigr
polymeric immunoglobulin receptor
chr1_+_167618246 6.589 ENSMUST00000111380.1
Rxrg
retinoid X receptor gamma
chr10_+_40629987 6.311 ENSMUST00000019977.7
Ddo
D-aspartate oxidase
chr6_+_41392356 6.241 ENSMUST00000049079.7
Gm5771
predicted gene 5771
chr4_-_42756543 6.039 ENSMUST00000102957.3
Ccl19
chemokine (C-C motif) ligand 19
chr16_+_26581704 5.760 ENSMUST00000096129.2
ENSMUST00000166294.2
ENSMUST00000174202.1
ENSMUST00000023156.6
Il1rap



interleukin 1 receptor accessory protein



chr19_-_11050500 5.751 ENSMUST00000099676.4
AW112010
expressed sequence AW112010
chr4_+_42629719 5.712 ENSMUST00000166898.2
Gm2564
predicted gene 2564
chr2_-_173218879 5.573 ENSMUST00000109116.2
ENSMUST00000029018.7
Zbp1

Z-DNA binding protein 1

chr6_+_41458923 5.487 ENSMUST00000031910.7
Prss1
protease, serine, 1 (trypsin 1)
chr19_+_34583528 5.291 ENSMUST00000102825.3
Ifit3
interferon-induced protein with tetratricopeptide repeats 3
chr19_+_34607927 5.209 ENSMUST00000076249.5
I830012O16Rik
RIKEN cDNA I830012O16 gene
chr8_-_45333189 5.052 ENSMUST00000095328.4
Cyp4v3
cytochrome P450, family 4, subfamily v, polypeptide 3
chr12_+_104406704 4.931 ENSMUST00000021506.5
Serpina3n
serine (or cysteine) peptidase inhibitor, clade A, member 3N
chr19_+_34640871 4.714 ENSMUST00000102824.3
Ifit1
interferon-induced protein with tetratricopeptide repeats 1
chr18_+_60212080 4.686 ENSMUST00000031549.5
Gm4951
predicted gene 4951
chr4_+_42114817 4.471 ENSMUST00000098123.3
Gm13304
predicted gene 13304
chr16_+_43363855 4.310 ENSMUST00000156367.1
Zbtb20
zinc finger and BTB domain containing 20
chr4_+_41903610 4.292 ENSMUST00000098128.3
Gm21541
predicted gene, 21541
chr14_+_41105359 4.154 ENSMUST00000047286.6
Mat1a
methionine adenosyltransferase I, alpha
chr19_-_46148369 4.053 ENSMUST00000026259.9
Pitx3
paired-like homeodomain transcription factor 3
chr8_+_107150621 4.019 ENSMUST00000034400.3
Cyb5b
cytochrome b5 type B
chr4_-_42773993 3.978 ENSMUST00000095114.4
Ccl21a
chemokine (C-C motif) ligand 21A (serine)
chr10_+_87860030 3.910 ENSMUST00000062862.6
Igf1
insulin-like growth factor 1
chr4_+_42255767 3.872 ENSMUST00000178864.1
Ccl21b
chemokine (C-C motif) ligand 21B (leucine)
chr6_-_23839137 3.767 ENSMUST00000166458.2
ENSMUST00000142913.2
ENSMUST00000115357.1
ENSMUST00000069074.7
ENSMUST00000115361.2
ENSMUST00000018122.7
ENSMUST00000115355.1
ENSMUST00000115356.2
Cadps2







Ca2+-dependent activator protein for secretion 2







chr11_+_70459940 3.756 ENSMUST00000147289.1
ENSMUST00000126105.1
Zmynd15

zinc finger, MYND-type containing 15

chr5_+_114923234 3.704 ENSMUST00000031540.4
ENSMUST00000112143.3
Oasl1

2'-5' oligoadenylate synthetase-like 1

chr16_+_23609895 3.673 ENSMUST00000038423.5
Rtp4
receptor transporter protein 4
chr5_-_139814025 3.435 ENSMUST00000146780.1
Tmem184a
transmembrane protein 184a
chr11_-_83530505 3.311 ENSMUST00000035938.2
Ccl5
chemokine (C-C motif) ligand 5
chr11_-_48992226 3.243 ENSMUST00000059930.2
ENSMUST00000068063.3
Gm12185
Tgtp1
predicted gene 12185
T cell specific GTPase 1
chr3_-_151749877 3.199 ENSMUST00000029671.7
Ifi44
interferon-induced protein 44
chr8_-_71537402 3.135 ENSMUST00000051672.7
Bst2
bone marrow stromal cell antigen 2
chr6_+_90550789 3.123 ENSMUST00000130418.1
ENSMUST00000032175.8
Aldh1l1

aldehyde dehydrogenase 1 family, member L1

chr15_-_77596110 3.078 ENSMUST00000089465.4
Apol10b
apolipoprotein L 10B
chr2_+_155382186 3.064 ENSMUST00000134218.1
Trp53inp2
transformation related protein 53 inducible nuclear protein 2
chr1_-_173490933 2.965 ENSMUST00000160565.2
Gm4955
predicted gene 4955
chr9_-_48835932 2.908 ENSMUST00000093852.3
Zbtb16
zinc finger and BTB domain containing 16
chr16_-_35871544 2.895 ENSMUST00000042665.8
Parp14
poly (ADP-ribose) polymerase family, member 14
chr15_-_77533312 2.751 ENSMUST00000062562.5
Apol7c
apolipoprotein L 7c
chr9_-_106476590 2.747 ENSMUST00000112479.2
Parp3
poly (ADP-ribose) polymerase family, member 3
chr9_-_106476104 2.744 ENSMUST00000156426.1
Parp3
poly (ADP-ribose) polymerase family, member 3
chr3_+_81932601 2.718 ENSMUST00000029649.2
Ctso
cathepsin O
chr16_+_43235856 2.647 ENSMUST00000146708.1
Zbtb20
zinc finger and BTB domain containing 20
chr11_+_58215028 2.647 ENSMUST00000108836.1
Irgm2
immunity-related GTPase family M member 2
chr14_-_7994563 2.576 ENSMUST00000026315.7
Dnase1l3
deoxyribonuclease 1-like 3
chr11_+_58199556 2.565 ENSMUST00000058704.8
ENSMUST00000035266.4
ENSMUST00000094169.4
ENSMUST00000168280.1
Irgm2
Igtp


immunity-related GTPase family M member 2
interferon gamma induced GTPase


chr17_+_34187545 2.548 ENSMUST00000170086.1
Tap1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr3_+_142560052 2.539 ENSMUST00000106222.2
Gbp3
guanylate binding protein 3
chr1_-_173599074 2.532 ENSMUST00000150649.1
ENSMUST00000180215.1
ENSMUST00000097462.2
Pydc4


pyrin domain containing 4


chr3_+_142560108 2.495 ENSMUST00000128609.1
ENSMUST00000029935.7
Gbp3

guanylate binding protein 3

chr4_-_46536096 2.488 ENSMUST00000102924.2
Trim14
tripartite motif-containing 14
chr3_+_142560351 2.466 ENSMUST00000106221.1
Gbp3
guanylate binding protein 3
chr9_-_106476372 2.462 ENSMUST00000123555.1
ENSMUST00000125850.1
Parp3

poly (ADP-ribose) polymerase family, member 3

chr10_+_116301374 2.461 ENSMUST00000092167.5
Ptprb
protein tyrosine phosphatase, receptor type, B
chr18_-_3299537 2.440 ENSMUST00000129435.1
ENSMUST00000122958.1
Crem

cAMP responsive element modulator

chr17_-_34862122 2.399 ENSMUST00000154526.1
Cfb
complement factor B
chr6_+_121245903 2.396 ENSMUST00000032198.9
Usp18
ubiquitin specific peptidase 18
chr17_+_34187789 2.371 ENSMUST00000041633.8
Tap1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr4_-_46536134 2.368 ENSMUST00000046897.6
Trim14
tripartite motif-containing 14
chr7_-_141266415 2.294 ENSMUST00000106023.1
ENSMUST00000097952.2
ENSMUST00000026571.4
Irf7


interferon regulatory factor 7


chr1_+_173673651 2.272 ENSMUST00000085876.4
Pydc3
pyrin domain containing 3
chr7_+_107567445 2.252 ENSMUST00000120990.1
Olfml1
olfactomedin-like 1
chr5_-_139813237 2.224 ENSMUST00000110832.1
Tmem184a
transmembrane protein 184a
chr17_-_34862473 2.222 ENSMUST00000025229.4
ENSMUST00000176203.2
ENSMUST00000128767.1
Cfb


complement factor B


chr16_-_24393588 2.203 ENSMUST00000181640.1
1110054M08Rik
RIKEN cDNA 1110054M08 gene
chr16_+_10488175 2.194 ENSMUST00000023147.6
Ciita
class II transactivator
chr11_-_70459957 2.153 ENSMUST00000019064.2
Cxcl16
chemokine (C-X-C motif) ligand 16
chr2_-_36104060 2.102 ENSMUST00000112961.3
ENSMUST00000112966.3
Lhx6

LIM homeobox protein 6

chr7_-_104507812 2.088 ENSMUST00000033211.7
ENSMUST00000071069.6
Trim30d

tripartite motif-containing 30D

chr17_-_34187219 2.079 ENSMUST00000173831.1
Psmb9
proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)
chr4_+_108834601 2.067 ENSMUST00000030296.8
Txndc12
thioredoxin domain containing 12 (endoplasmic reticulum)
chr14_-_11162008 2.026 ENSMUST00000162278.1
ENSMUST00000160340.1
ENSMUST00000160956.1
Fhit


fragile histidine triad gene


chr12_+_103434211 1.954 ENSMUST00000079294.5
ENSMUST00000076788.5
ENSMUST00000076702.5
ENSMUST00000066701.6
ENSMUST00000085065.5
ENSMUST00000140838.1
Ifi27





interferon, alpha-inducible protein 27





chr2_-_181241955 1.929 ENSMUST00000121484.1
Helz2
helicase with zinc finger 2, transcriptional coactivator
chr1_+_175631996 1.925 ENSMUST00000040250.8
Kmo
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr3_+_19957088 1.919 ENSMUST00000108328.1
Cp
ceruloplasmin
chr11_-_100704217 1.918 ENSMUST00000017974.6
Dhx58
DEXH (Asp-Glu-X-His) box polypeptide 58
chr18_-_39489880 1.885 ENSMUST00000152853.1
Nr3c1
nuclear receptor subfamily 3, group C, member 1
chr1_+_52119438 1.874 ENSMUST00000070968.7
Stat1
signal transducer and activator of transcription 1
chr2_+_122147680 1.872 ENSMUST00000102476.4
B2m
beta-2 microglobulin
chr2_-_181242020 1.868 ENSMUST00000094203.4
ENSMUST00000108831.1
Helz2

helicase with zinc finger 2, transcriptional coactivator

chr11_-_48871408 1.863 ENSMUST00000097271.2
Irgm1
immunity-related GTPase family M member 1
chr18_-_3299452 1.860 ENSMUST00000126578.1
Crem
cAMP responsive element modulator
chr2_-_167062607 1.838 ENSMUST00000128676.1
Znfx1
zinc finger, NFX1-type containing 1
chr2_-_62646146 1.829 ENSMUST00000112459.3
ENSMUST00000028259.5
Ifih1

interferon induced with helicase C domain 1

chr1_+_175632169 1.803 ENSMUST00000097458.3
Kmo
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr1_-_105356658 1.794 ENSMUST00000058688.5
ENSMUST00000172299.1
Rnf152

ring finger protein 152

chr16_+_43364145 1.786 ENSMUST00000148775.1
Zbtb20
zinc finger and BTB domain containing 20
chr1_+_13668739 1.761 ENSMUST00000088542.3
Xkr9
X Kell blood group precursor related family member 9 homolog
chr5_-_91402905 1.750 ENSMUST00000121044.2
Btc
betacellulin, epidermal growth factor family member
chr3_+_19957037 1.696 ENSMUST00000091309.5
ENSMUST00000108329.1
ENSMUST00000003714.6
Cp


ceruloplasmin


chr7_-_126594941 1.663 ENSMUST00000058429.5
Il27
interleukin 27
chr14_+_28511344 1.620 ENSMUST00000112272.1
Wnt5a
wingless-related MMTV integration site 5A
chr12_+_37241729 1.615 ENSMUST00000160768.1
Agmo
alkylglycerol monooxygenase
chr11_+_48978889 1.578 ENSMUST00000179282.1
ENSMUST00000056759.4
Olfr56

olfactory receptor 56

chr6_-_39118211 1.570 ENSMUST00000038398.6
Parp12
poly (ADP-ribose) polymerase family, member 12
chr3_+_55116174 1.567 ENSMUST00000146109.1
Spg20
spastic paraplegia 20, spartin (Troyer syndrome) homolog (human)
chr3_+_19957240 1.557 ENSMUST00000108325.2
Cp
ceruloplasmin
chr5_-_120887582 1.550 ENSMUST00000086368.5
Oas1g
2'-5' oligoadenylate synthetase 1G
chr11_-_78984946 1.545 ENSMUST00000108268.3
Lgals9
lectin, galactose binding, soluble 9
chr19_-_4477447 1.524 ENSMUST00000059295.3
Syt12
synaptotagmin XII
chr4_+_135728116 1.523 ENSMUST00000102546.3
Il22ra1
interleukin 22 receptor, alpha 1
chr11_-_78984831 1.518 ENSMUST00000073001.4
ENSMUST00000108269.3
Lgals9

lectin, galactose binding, soluble 9

chr11_+_119393060 1.493 ENSMUST00000131035.2
ENSMUST00000093902.5
Rnf213

ring finger protein 213

chr11_+_72301613 1.481 ENSMUST00000151440.1
ENSMUST00000146233.1
ENSMUST00000140842.2
Xaf1


XIAP associated factor 1


chr3_+_94954075 1.474 ENSMUST00000107260.2
ENSMUST00000142311.1
ENSMUST00000137088.1
ENSMUST00000152869.1
ENSMUST00000107254.1
ENSMUST00000107253.1
Rfx5





regulatory factor X, 5 (influences HLA class II expression)





chr9_+_20868628 1.456 ENSMUST00000043911.7
A230050P20Rik
RIKEN cDNA A230050P20 gene
chr3_+_137671524 1.429 ENSMUST00000166899.2
Gm21962
predicted gene, 21962
chr10_+_13966268 1.429 ENSMUST00000015645.4
Hivep2
human immunodeficiency virus type I enhancer binding protein 2
chr11_-_48871344 1.426 ENSMUST00000049519.3
Irgm1
immunity-related GTPase family M member 1
chr11_+_49050733 1.387 ENSMUST00000102785.1
Olfr56
olfactory receptor 56
chr6_+_29529277 1.379 ENSMUST00000163511.1
Irf5
interferon regulatory factor 5
chr10_+_39612934 1.362 ENSMUST00000019987.6
Traf3ip2
TRAF3 interacting protein 2
chr13_+_74639866 1.342 ENSMUST00000169114.1
Erap1
endoplasmic reticulum aminopeptidase 1
chr1_+_58505135 1.308 ENSMUST00000160947.1
ENSMUST00000129740.2
ENSMUST00000139825.1
Gm15834


predicted gene 15834


chr16_+_24393350 1.304 ENSMUST00000038053.6
Lpp
LIM domain containing preferred translocation partner in lipoma
chr13_-_23710714 1.304 ENSMUST00000091707.6
ENSMUST00000006787.7
ENSMUST00000091706.6
Hfe


hemochromatosis


chr16_+_42907563 1.286 ENSMUST00000151244.1
ENSMUST00000114694.2
Zbtb20

zinc finger and BTB domain containing 20

chr16_+_35938470 1.277 ENSMUST00000114878.1
Parp9
poly (ADP-ribose) polymerase family, member 9
chr11_-_51857624 1.270 ENSMUST00000020655.7
ENSMUST00000109090.1
Phf15

PHD finger protein 15

chr2_-_132111440 1.244 ENSMUST00000128899.1
Slc23a2
solute carrier family 23 (nucleobase transporters), member 2
chr8_-_111338152 1.228 ENSMUST00000056157.7
ENSMUST00000120432.1
Mlkl

mixed lineage kinase domain-like

chr18_+_61045139 1.223 ENSMUST00000025522.4
ENSMUST00000115274.1
Pdgfrb

platelet derived growth factor receptor, beta polypeptide

chr17_+_43389436 1.215 ENSMUST00000113599.1
Gpr116
G protein-coupled receptor 116
chr1_+_132008285 1.209 ENSMUST00000146432.1
Elk4
ELK4, member of ETS oncogene family
chr7_+_104244496 1.205 ENSMUST00000106854.1
ENSMUST00000143414.1
Trim34a

tripartite motif-containing 34A

chr7_+_104244465 1.185 ENSMUST00000106848.1
Trim34a
tripartite motif-containing 34A
chr5_-_120777628 1.173 ENSMUST00000044833.8
Oas3
2'-5' oligoadenylate synthetase 3
chr5_-_92348871 1.171 ENSMUST00000038816.6
ENSMUST00000118006.1
Cxcl10

chemokine (C-X-C motif) ligand 10

chr19_-_21472552 1.167 ENSMUST00000087600.3
Gda
guanine deaminase
chr19_-_4477119 1.146 ENSMUST00000166191.1
Syt12
synaptotagmin XII
chr11_-_83020788 1.138 ENSMUST00000038141.8
ENSMUST00000092838.4
Slfn8

schlafen 8

chr1_+_171018920 1.134 ENSMUST00000078825.4
Fcgr4
Fc receptor, IgG, low affinity IV
chr10_+_128270546 1.126 ENSMUST00000105238.3
ENSMUST00000085708.2
Stat2

signal transducer and activator of transcription 2

chr1_-_78197112 1.112 ENSMUST00000087086.6
Pax3
paired box gene 3
chr10_-_94944578 1.109 ENSMUST00000099337.3
Plxnc1
plexin C1
chr5_-_120812484 1.108 ENSMUST00000125547.1
Oas1c
2'-5' oligoadenylate synthetase 1C
chr17_+_86167777 1.091 ENSMUST00000097275.2
Prkce
protein kinase C, epsilon
chr8_+_61928081 1.073 ENSMUST00000154398.1
ENSMUST00000093485.2
ENSMUST00000156980.1
ENSMUST00000070631.7
Ddx60



DEAD (Asp-Glu-Ala-Asp) box polypeptide 60



chr5_-_120812506 1.071 ENSMUST00000117193.1
ENSMUST00000130045.1
Oas1c

2'-5' oligoadenylate synthetase 1C

chr8_-_84773381 1.058 ENSMUST00000109764.1
Nfix
nuclear factor I/X
chr8_-_111337793 1.055 ENSMUST00000145862.1
Mlkl
mixed lineage kinase domain-like
chr19_+_6164433 1.050 ENSMUST00000045042.7
Batf2
basic leucine zipper transcription factor, ATF-like 2
chr16_-_35939082 1.044 ENSMUST00000081933.7
ENSMUST00000114885.1
Dtx3l

deltex 3-like (Drosophila)

chr8_+_127064107 1.043 ENSMUST00000162536.1
ENSMUST00000026921.6
ENSMUST00000162665.1
ENSMUST00000160766.1
ENSMUST00000162602.1
ENSMUST00000162531.1
ENSMUST00000160581.1
ENSMUST00000161355.1
ENSMUST00000159537.1
Pard3








par-3 (partitioning defective 3) homolog (C. elegans)








chr12_+_37242030 1.008 ENSMUST00000160390.1
Agmo
alkylglycerol monooxygenase
chr7_+_104244449 0.999 ENSMUST00000106849.2
ENSMUST00000060315.5
Trim34a

tripartite motif-containing 34A

chr1_+_85650008 0.987 ENSMUST00000054279.8
ENSMUST00000147552.1
ENSMUST00000153574.1
ENSMUST00000150967.1
Sp100



nuclear antigen Sp100



chr4_-_40239700 0.980 ENSMUST00000142055.1
Ddx58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr1_-_78196832 0.973 ENSMUST00000004994.9
Pax3
paired box gene 3
chr12_+_90738201 0.970 ENSMUST00000181874.1
Gm26512
predicted gene, 26512
chr16_+_8470763 0.955 ENSMUST00000046470.9
ENSMUST00000150790.1
ENSMUST00000142899.1
Mettl22


methyltransferase like 22


chr3_+_66981352 0.954 ENSMUST00000162036.1
Rsrc1
arginine/serine-rich coiled-coil 1
chr1_+_85649988 0.952 ENSMUST00000155094.1
Sp100
nuclear antigen Sp100
chr15_-_76243401 0.950 ENSMUST00000165738.1
ENSMUST00000075689.6
Parp10

poly (ADP-ribose) polymerase family, member 10

chr19_-_6084873 0.948 ENSMUST00000160977.1
ENSMUST00000159859.1
Zfpl1

zinc finger like protein 1

chr4_-_40239779 0.939 ENSMUST00000037907.6
Ddx58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr13_+_42866247 0.932 ENSMUST00000131942.1
Phactr1
phosphatase and actin regulator 1
chr16_+_35938972 0.927 ENSMUST00000023622.6
ENSMUST00000114877.1
Parp9

poly (ADP-ribose) polymerase family, member 9

chr1_-_170110491 0.924 ENSMUST00000027985.2
Ddr2
discoidin domain receptor family, member 2
chr12_+_37241633 0.923 ENSMUST00000049874.7
Agmo
alkylglycerol monooxygenase
chr6_+_39381175 0.896 ENSMUST00000031986.4
Rab19
RAB19, member RAS oncogene family
chr16_-_44139630 0.873 ENSMUST00000137557.1
ENSMUST00000147025.1
Atp6v1a

ATPase, H+ transporting, lysosomal V1 subunit A

chr2_-_173276144 0.870 ENSMUST00000139306.1
Pmepa1
prostate transmembrane protein, androgen induced 1
chr18_+_37400845 0.866 ENSMUST00000057228.1
Pcdhb9
protocadherin beta 9
chr14_+_55604550 0.854 ENSMUST00000138037.1
Irf9
interferon regulatory factor 9
chr11_+_43474276 0.853 ENSMUST00000173002.1
ENSMUST00000057679.3
C1qtnf2

C1q and tumor necrosis factor related protein 2

chr4_+_45972233 0.850 ENSMUST00000102929.1
Tdrd7
tudor domain containing 7
chr9_+_118478344 0.824 ENSMUST00000035020.8
Eomes
eomesodermin homolog (Xenopus laevis)
chr14_-_63543931 0.819 ENSMUST00000058679.5
Mtmr9
myotubularin related protein 9
chr6_-_125231772 0.801 ENSMUST00000043422.7
Tapbpl
TAP binding protein-like
chr7_+_104300230 0.781 ENSMUST00000106847.1
Trim34b
tripartite motif-containing 34B
chr18_-_39490649 0.780 ENSMUST00000115567.1
Nr3c1
nuclear receptor subfamily 3, group C, member 1
chr2_-_84743655 0.774 ENSMUST00000181711.1
Gm19426
predicted gene, 19426
chr1_+_180942500 0.772 ENSMUST00000159436.1
Tmem63a
transmembrane protein 63a
chr14_+_48446128 0.766 ENSMUST00000124720.1
Tmem260
transmembrane protein 260
chr4_+_138972885 0.764 ENSMUST00000123636.1
ENSMUST00000043042.3
ENSMUST00000050949.2
Tmco4


transmembrane and coiled-coil domains 4


chr7_+_44836286 0.763 ENSMUST00000033015.7
Il4i1
interleukin 4 induced 1
chr1_+_85650044 0.762 ENSMUST00000066427.4
Sp100
nuclear antigen Sp100
chr11_-_83020722 0.760 ENSMUST00000108152.2
Slfn8
schlafen 8
chr8_+_127064022 0.751 ENSMUST00000160272.1
ENSMUST00000079777.5
ENSMUST00000162907.1
Pard3


par-3 (partitioning defective 3) homolog (C. elegans)


chr5_+_114896936 0.717 ENSMUST00000031542.9
ENSMUST00000146072.1
ENSMUST00000150361.1
Oasl2


2'-5' oligoadenylate synthetase-like 2


chr10_+_63061582 0.686 ENSMUST00000020266.8
ENSMUST00000178684.1
Pbld1

phenazine biosynthesis-like protein domain containing 1

chr19_+_12460749 0.685 ENSMUST00000081035.7
Mpeg1
macrophage expressed gene 1
chr1_+_143640664 0.684 ENSMUST00000038252.2
B3galt2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr7_-_46795881 0.673 ENSMUST00000107653.1
ENSMUST00000107654.1
ENSMUST00000014562.7
ENSMUST00000152759.1
Hps5



Hermansky-Pudlak syndrome 5 homolog (human)



chr4_+_94739518 0.659 ENSMUST00000071168.5
Tek
endothelial-specific receptor tyrosine kinase
chr9_+_32116040 0.644 ENSMUST00000174641.1
Arhgap32
Rho GTPase activating protein 32
chr5_-_90223923 0.635 ENSMUST00000118816.1
ENSMUST00000048363.7
Cox18

cytochrome c oxidase assembly protein 18

chr5_-_120907510 0.622 ENSMUST00000080322.7
Oas1a
2'-5' oligoadenylate synthetase 1A
chr6_+_57580992 0.600 ENSMUST00000031817.8
Herc6
hect domain and RLD 6
chr1_-_173912904 0.600 ENSMUST00000009340.8
Mnda
myeloid cell nuclear differentiation antigen
chr7_-_46795661 0.600 ENSMUST00000123725.1
Hps5
Hermansky-Pudlak syndrome 5 homolog (human)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 13.6 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
3.3 10.0 GO:2000547 regulation of dendritic cell dendrite assembly(GO:2000547)
2.7 8.0 GO:1990166 protein localization to site of double-strand break(GO:1990166)
2.1 6.3 GO:0006533 aspartate catabolic process(GO:0006533)
1.9 5.7 GO:1904933 regulation of cell proliferation in midbrain(GO:1904933)
1.4 5.8 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
1.1 2.1 GO:0002589 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589)
1.0 5.2 GO:0061739 protein lipidation involved in autophagosome assembly(GO:0061739)
1.0 3.1 GO:0042560 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
1.0 4.2 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
1.0 3.0 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
1.0 4.9 GO:0046967 cytosol to ER transport(GO:0046967)
1.0 3.8 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.9 5.7 GO:0018992 germ-line sex determination(GO:0018992)
0.9 1.9 GO:0002481 antigen processing and presentation of exogenous peptide antigen via MHC class Ib(GO:0002477) antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent(GO:0002481)
0.9 23.2 GO:0035455 response to interferon-alpha(GO:0035455)
0.8 3.3 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.8 3.1 GO:2000562 negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.7 3.3 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.7 3.9 GO:1904075 regulation of oligodendrocyte apoptotic process(GO:1900141) negative regulation of oligodendrocyte apoptotic process(GO:1900142) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.6 3.7 GO:0035547 interferon-beta secretion(GO:0035546) regulation of interferon-beta secretion(GO:0035547) positive regulation of interferon-beta secretion(GO:0035549)
0.6 3.7 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.6 7.9 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.6 9.3 GO:0031000 response to caffeine(GO:0031000)
0.5 1.6 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.5 3.0 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.4 16.3 GO:0035456 response to interferon-beta(GO:0035456)
0.4 1.2 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.4 1.2 GO:0035441 cell migration involved in vasculogenesis(GO:0035441) metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.4 1.2 GO:0046098 guanine metabolic process(GO:0046098)
0.4 1.9 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.4 2.9 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.4 2.1 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.3 1.0 GO:0060809 mesodermal to mesenchymal transition involved in gastrulation(GO:0060809)
0.3 1.8 GO:0003383 apical constriction(GO:0003383)
0.3 1.2 GO:1901740 negative regulation of myoblast fusion(GO:1901740)
0.3 4.6 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.3 2.2 GO:0045348 positive regulation of MHC class II biosynthetic process(GO:0045348)
0.3 1.1 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.3 3.8 GO:1990504 dense core granule exocytosis(GO:1990504)
0.3 2.0 GO:0015961 diadenosine polyphosphate catabolic process(GO:0015961)
0.2 11.7 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.2 8.7 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.2 0.7 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.2 3.5 GO:0046485 ether lipid metabolic process(GO:0046485)
0.2 1.7 GO:0060330 regulation of response to interferon-gamma(GO:0060330)
0.2 0.6 GO:0007208 phospholipase C-activating serotonin receptor signaling pathway(GO:0007208)
0.2 3.6 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.2 2.1 GO:0014807 regulation of somitogenesis(GO:0014807)
0.2 4.5 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.2 0.6 GO:0061076 negative regulation of neural retina development(GO:0061076) negative regulation of retina development in camera-type eye(GO:1902867) negative regulation of amacrine cell differentiation(GO:1902870)
0.2 1.7 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.2 0.5 GO:0048687 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
0.2 1.2 GO:0045351 type I interferon biosynthetic process(GO:0045351)
0.2 0.5 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.2 1.1 GO:0038095 Fc-epsilon receptor signaling pathway(GO:0038095)
0.2 6.6 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.2 1.8 GO:0035810 positive regulation of urine volume(GO:0035810)
0.2 5.2 GO:0046688 response to copper ion(GO:0046688)
0.2 2.6 GO:0010623 programmed cell death involved in cell development(GO:0010623)
0.1 1.2 GO:0060700 regulation of ribonuclease activity(GO:0060700)
0.1 1.1 GO:0071357 type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.1 1.5 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.1 0.9 GO:0010991 regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 1.8 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.1 0.9 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.1 0.6 GO:0051204 protein insertion into mitochondrial membrane(GO:0051204)
0.1 0.4 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.1 4.9 GO:0006953 acute-phase response(GO:0006953)
0.1 1.9 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.1 0.5 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.1 2.4 GO:0035634 response to stilbenoid(GO:0035634)
0.1 1.7 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.1 5.0 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.1 10.4 GO:0007586 digestion(GO:0007586)
0.1 0.9 GO:0032494 response to peptidoglycan(GO:0032494)
0.1 0.5 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.1 2.7 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 0.3 GO:0048014 Tie signaling pathway(GO:0048014)
0.1 0.2 GO:2001045 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 1.1 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 0.2 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.1 0.5 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0 1.0 GO:0042832 defense response to protozoan(GO:0042832)
0.0 5.9 GO:0019395 fatty acid oxidation(GO:0019395)
0.0 0.2 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.2 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.0 1.9 GO:0070207 protein homotrimerization(GO:0070207)
0.0 1.5 GO:0034341 response to interferon-gamma(GO:0034341)
0.0 3.1 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 1.2 GO:0070932 histone H3 deacetylation(GO:0070932)
0.0 0.4 GO:0021678 third ventricle development(GO:0021678)
0.0 0.3 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 0.1 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.0 0.9 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.1 GO:0048861 histone H3-K27 acetylation(GO:0043974) leukemia inhibitory factor signaling pathway(GO:0048861) regulation of histone H3-K27 acetylation(GO:1901674)
0.0 1.1 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.0 1.0 GO:0046677 response to antibiotic(GO:0046677)
0.0 3.0 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.9 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.0 0.2 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.0 0.5 GO:0032689 negative regulation of interferon-gamma production(GO:0032689)
0.0 0.3 GO:0048305 immunoglobulin secretion(GO:0048305)
0.0 0.5 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.0 2.7 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 1.3 GO:0019882 antigen processing and presentation(GO:0019882)
0.0 0.3 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.0 1.8 GO:0007286 spermatid development(GO:0007286)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 12.7 GO:0020003 symbiont-containing vacuole(GO:0020003)
0.7 5.5 GO:0042825 TAP complex(GO:0042825)
0.4 3.9 GO:0042567 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867) insulin-like growth factor ternary complex(GO:0042567)
0.4 2.1 GO:1990111 spermatoproteasome complex(GO:1990111)
0.4 3.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.3 1.3 GO:0031084 BLOC-2 complex(GO:0031084)
0.3 13.6 GO:0055038 recycling endosome membrane(GO:0055038)
0.2 1.8 GO:0033269 internode region of axon(GO:0033269)
0.2 3.3 GO:0044754 autolysosome(GO:0044754)
0.2 2.9 GO:0043657 host(GO:0018995) host cell(GO:0043657)
0.2 1.7 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.2 6.5 GO:0090734 site of double-strand break(GO:0035861) site of DNA damage(GO:0090734)
0.1 0.1 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 6.5 GO:0031901 early endosome membrane(GO:0031901)
0.1 5.2 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 3.3 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 8.1 GO:0072562 blood microparticle(GO:0072562)
0.0 0.9 GO:0033391 chromatoid body(GO:0033391)
0.0 3.1 GO:0005776 autophagosome(GO:0005776)
0.0 2.0 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 3.8 GO:0042734 presynaptic membrane(GO:0042734)
0.0 6.3 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 6.5 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 2.4 GO:0031301 integral component of organelle membrane(GO:0031301)
0.0 0.1 GO:0099053 activating signal cointegrator 1 complex(GO:0099053)
0.0 8.9 GO:0045177 apical part of cell(GO:0045177)
0.0 0.2 GO:0033176 proton-transporting V-type ATPase complex(GO:0033176)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)
0.0 1.1 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 0.2 GO:0034451 centriolar satellite(GO:0034451)
0.0 2.4 GO:0043235 receptor complex(GO:0043235)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.1 GO:0003692 left-handed Z-DNA binding(GO:0003692)
1.6 6.3 GO:0003884 D-amino-acid oxidase activity(GO:0003884)
1.5 6.0 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
1.5 14.7 GO:0019763 immunoglobulin receptor activity(GO:0019763)
1.4 5.8 GO:0002114 interleukin-33 binding(GO:0002113) interleukin-33 receptor activity(GO:0002114)
1.2 3.5 GO:0050479 glyceryl-ether monooxygenase activity(GO:0050479)
1.1 3.3 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
1.0 3.1 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
1.0 4.2 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
1.0 4.9 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980)
0.9 3.6 GO:0031849 olfactory receptor binding(GO:0031849)
0.9 8.0 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.8 9.3 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.7 5.2 GO:0019776 Atg8 ligase activity(GO:0019776)
0.7 2.1 GO:0019153 protein-disulfide reductase (glutathione) activity(GO:0019153)
0.7 6.6 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.6 3.0 GO:0038049 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.5 1.6 GO:0005110 frizzled-2 binding(GO:0005110)
0.5 5.2 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.5 1.5 GO:0042015 interleukin-20 binding(GO:0042015)
0.5 2.0 GO:0047710 bis(5'-adenosyl)-triphosphatase activity(GO:0047710)
0.5 16.9 GO:0008009 chemokine activity(GO:0008009)
0.4 3.1 GO:0016936 galactoside binding(GO:0016936)
0.4 1.2 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.3 0.6 GO:0046978 TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.3 1.1 GO:0035276 ethanol binding(GO:0035276)
0.3 0.8 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.2 3.7 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.2 5.7 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.2 1.9 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.2 3.2 GO:1990459 transferrin receptor binding(GO:1990459)
0.2 2.9 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.2 0.6 GO:0001587 Gq/11-coupled serotonin receptor activity(GO:0001587)
0.2 0.7 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.1 1.3 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 2.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 1.2 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 3.9 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 2.1 GO:0070628 proteasome binding(GO:0070628)
0.1 0.9 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 1.1 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 30.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 0.5 GO:0033142 progesterone receptor binding(GO:0033142)
0.1 2.0 GO:0005521 lamin binding(GO:0005521)
0.1 0.5 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 0.3 GO:0070052 collagen V binding(GO:0070052)
0.1 5.5 GO:0003725 double-stranded RNA binding(GO:0003725)
0.1 0.6 GO:0030332 cyclin binding(GO:0030332)
0.1 1.6 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 6.9 GO:0020037 heme binding(GO:0020037)
0.1 2.1 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.2 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 1.8 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 9.1 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 2.7 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.1 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.0 0.2 GO:0001515 opioid peptide activity(GO:0001515)
0.0 1.8 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.5 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 2.1 GO:0004520 endodeoxyribonuclease activity(GO:0004520)
0.0 6.1 GO:0061660 Atg12 activating enzyme activity(GO:0019778) Atg8-specific protease activity(GO:0019786) Atg12 conjugating enzyme activity(GO:0061651) Atg12 ligase activity(GO:0061660)
0.0 9.7 GO:0005525 GTP binding(GO:0005525)
0.0 3.0 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.9 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.9 GO:0050699 WW domain binding(GO:0050699)
0.0 2.7 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.3 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.5 GO:0050681 androgen receptor binding(GO:0050681)
0.0 6.1 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.6 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 3.1 GO:0001047 core promoter binding(GO:0001047)
0.0 1.9 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.2 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 1.5 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 1.9 GO:0004386 helicase activity(GO:0004386)
0.0 1.0 GO:0008276 protein methyltransferase activity(GO:0008276)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.9 ST_TYPE_I_INTERFERON_PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.2 4.6 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.2 15.9 PID_IL4_2PATHWAY IL4-mediated signaling events
0.2 11.8 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 6.6 PID_RETINOIC_ACID_PATHWAY Retinoic acid receptors-mediated signaling
0.1 5.8 PID_IL1_PATHWAY IL1-mediated signaling events
0.1 3.9 PID_IGF1_PATHWAY IGF1 pathway
0.1 1.7 PID_IL27_PATHWAY IL27-mediated signaling events
0.1 3.9 PID_CD8_TCR_DOWNSTREAM_PATHWAY Downstream signaling in naïve CD8+ T cells
0.1 1.8 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.1 6.2 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.1 5.2 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.1 5.3 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 12.5 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 2.3 PID_TELOMERASE_PATHWAY Regulation of Telomerase
0.0 2.1 PID_RB_1PATHWAY Regulation of retinoblastoma protein
0.0 1.2 PID_CXCR3_PATHWAY CXCR3-mediated signaling events
0.0 2.0 SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 1.2 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.8 PID_SHP2_PATHWAY SHP2 signaling
0.0 5.0 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.9 PID_AURORA_A_PATHWAY Aurora A signaling
0.0 0.5 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 2.8 PID_P53_DOWNSTREAM_PATHWAY Direct p53 effectors
0.0 1.0 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.7 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 9.3 REACTOME_DEFENSINS Genes involved in Defensins
0.6 1.9 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.3 4.6 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade
0.3 6.3 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.3 6.0 REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.3 12.7 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.3 4.9 REACTOME_REGULATION_OF_IFNA_SIGNALING Genes involved in Regulation of IFNA signaling
0.2 5.6 REACTOME_RIP_MEDIATED_NFKB_ACTIVATION_VIA_DAI Genes involved in RIP-mediated NFkB activation via DAI
0.2 3.2 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism
0.2 7.5 REACTOME_INTERFERON_GAMMA_SIGNALING Genes involved in Interferon gamma signaling
0.1 4.2 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 5.2 REACTOME_METAL_ION_SLC_TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 5.3 REACTOME_IL1_SIGNALING Genes involved in Interleukin-1 signaling
0.1 9.6 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 2.7 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.1 1.2 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism
0.1 1.8 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 0.8 REACTOME_PD1_SIGNALING Genes involved in PD-1 signaling
0.1 1.8 REACTOME_SHC1_EVENTS_IN_ERBB4_SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.1 1.8 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.1 0.6 REACTOME_SEROTONIN_RECEPTORS Genes involved in Serotonin receptors
0.0 1.3 REACTOME_RIG_I_MDA5_MEDIATED_INDUCTION_OF_IFN_ALPHA_BETA_PATHWAYS Genes involved in RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
0.0 1.1 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.0 1.1 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 2.7 REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION Genes involved in MHC class II antigen presentation
0.0 1.2 REACTOME_CDK_MEDIATED_PHOSPHORYLATION_AND_REMOVAL_OF_CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0 0.3 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.0 1.2 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.5 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.5 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 1.2 REACTOME_DOWNSTREAM_SIGNAL_TRANSDUCTION Genes involved in Downstream signal transduction
0.0 2.1 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.1 REACTOME_PROLACTIN_RECEPTOR_SIGNALING Genes involved in Prolactin receptor signaling