Motif ID: Tal1

Z-value: 4.006


Transcription factors associated with Tal1:

Gene SymbolEntrez IDGene Name
Tal1 ENSMUSG00000028717.6 Tal1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tal1mm10_v2_chr4_+_115059507_1150595530.973.0e-22Click!


Activity profile for motif Tal1.

activity profile for motif Tal1


Sorted Z-values histogram for motif Tal1

Sorted Z-values for motif Tal1



Network of associatons between targets according to the STRING database.



First level regulatory network of Tal1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_132367879 62.649 ENSMUST00000142609.1
Tmcc2
transmembrane and coiled-coil domains 2
chr14_-_43875517 60.380 ENSMUST00000179200.1
Ear1
eosinophil-associated, ribonuclease A family, member 1
chr6_+_86078070 58.337 ENSMUST00000032069.5
Add2
adducin 2 (beta)
chr4_-_119189949 49.248 ENSMUST00000124626.1
Ermap
erythroblast membrane-associated protein
chr15_-_103251465 49.221 ENSMUST00000133600.1
ENSMUST00000134554.1
ENSMUST00000156927.1
ENSMUST00000149111.1
ENSMUST00000132836.1
Nfe2




nuclear factor, erythroid derived 2




chr17_+_40811089 48.765 ENSMUST00000024721.7
Rhag
Rhesus blood group-associated A glycoprotein
chr7_-_103853199 48.099 ENSMUST00000033229.3
Hbb-y
hemoglobin Y, beta-like embryonic chain
chr4_+_134864536 40.102 ENSMUST00000030627.7
Rhd
Rh blood group, D antigen
chr14_-_43819639 39.841 ENSMUST00000100691.3
Ear1
eosinophil-associated, ribonuclease A family, member 1
chr1_+_174172738 38.095 ENSMUST00000027817.7
Spta1
spectrin alpha, erythrocytic 1
chr11_+_32276400 37.793 ENSMUST00000020531.2
Hba-x
hemoglobin X, alpha-like embryonic chain in Hba complex
chr16_-_18621366 36.052 ENSMUST00000051160.2
Gp1bb
glycoprotein Ib, beta polypeptide
chr17_+_36869567 35.626 ENSMUST00000060524.9
Trim10
tripartite motif-containing 10
chr14_+_51853699 35.255 ENSMUST00000169070.1
ENSMUST00000074477.6
Ear6

eosinophil-associated, ribonuclease A family, member 6

chr1_+_131638485 34.727 ENSMUST00000112411.1
Ctse
cathepsin E
chr4_-_119190005 33.950 ENSMUST00000138395.1
ENSMUST00000156746.1
Ermap

erythroblast membrane-associated protein

chr17_-_26199008 33.878 ENSMUST00000142410.1
ENSMUST00000120333.1
ENSMUST00000039113.7
Pdia2


protein disulfide isomerase associated 2


chr11_+_32276893 33.124 ENSMUST00000145569.1
Hba-x
hemoglobin X, alpha-like embryonic chain in Hba complex
chr14_+_27000362 33.068 ENSMUST00000035433.8
Hesx1
homeobox gene expressed in ES cells
chr1_+_131638306 32.863 ENSMUST00000073350.6
Ctse
cathepsin E
chrX_+_8271642 32.153 ENSMUST00000115590.1
Slc38a5
solute carrier family 38, member 5
chr7_-_4397705 31.804 ENSMUST00000108590.2
Gp6
glycoprotein 6 (platelet)
chr15_+_80623499 30.516 ENSMUST00000043149.7
Grap2
GRB2-related adaptor protein 2
chr17_+_31208049 30.293 ENSMUST00000173776.1
Ubash3a
ubiquitin associated and SH3 domain containing, A
chr8_+_80494032 29.617 ENSMUST00000063359.6
Gypa
glycophorin A
chr8_+_84701430 29.160 ENSMUST00000037165.4
Lyl1
lymphoblastomic leukemia 1
chr7_+_110773658 27.818 ENSMUST00000143786.1
Ampd3
adenosine monophosphate deaminase 3
chr11_+_58918004 27.330 ENSMUST00000108818.3
ENSMUST00000020792.5
Btnl10

butyrophilin-like 10

chr8_-_85365317 25.485 ENSMUST00000034133.7
Mylk3
myosin light chain kinase 3
chr8_-_85365341 25.342 ENSMUST00000121972.1
Mylk3
myosin light chain kinase 3
chr17_-_28560704 24.646 ENSMUST00000114785.1
ENSMUST00000025062.3
Clps

colipase, pancreatic

chrX_+_93675088 24.265 ENSMUST00000045898.3
Pcyt1b
phosphate cytidylyltransferase 1, choline, beta isoform
chr9_-_21963568 23.791 ENSMUST00000006397.5
Epor
erythropoietin receptor
chr11_+_58917889 22.994 ENSMUST00000069941.6
Btnl10
butyrophilin-like 10
chr10_-_79788924 22.626 ENSMUST00000020573.6
Prss57
protease, serine 57
chr7_-_100467149 22.548 ENSMUST00000184420.1
RP23-308M1.2
RP23-308M1.2
chr7_+_99594605 22.222 ENSMUST00000162290.1
Arrb1
arrestin, beta 1
chr9_+_21029373 22.042 ENSMUST00000001040.5
Icam4
intercellular adhesion molecule 4, Landsteiner-Wiener blood group
chr2_+_129228022 21.410 ENSMUST00000148548.1
A730036I17Rik
RIKEN cDNA A730036I17 gene
chr13_+_108316395 21.059 ENSMUST00000171178.1
Depdc1b
DEP domain containing 1B
chr2_+_84988194 20.878 ENSMUST00000028466.5
Prg3
proteoglycan 3
chr10_-_62342674 19.803 ENSMUST00000143179.1
ENSMUST00000130422.1
Hk1

hexokinase 1

chr6_+_41354105 19.635 ENSMUST00000072103.5
Try10
trypsin 10
chr7_-_99238564 19.104 ENSMUST00000064231.7
Mogat2
monoacylglycerol O-acyltransferase 2
chr5_+_115845229 18.878 ENSMUST00000137952.1
ENSMUST00000148245.1
Cit

citron

chr6_+_41458923 18.757 ENSMUST00000031910.7
Prss1
protease, serine, 1 (trypsin 1)
chr11_-_80080928 17.653 ENSMUST00000103233.3
ENSMUST00000061283.8
Crlf3

cytokine receptor-like factor 3

chr6_-_41314700 17.037 ENSMUST00000064324.5
Try5
trypsin 5
chr10_-_80421847 16.630 ENSMUST00000156244.1
Tcf3
transcription factor 3
chr19_+_58759700 15.861 ENSMUST00000026081.3
Pnliprp2
pancreatic lipase-related protein 2
chr11_+_70639118 15.671 ENSMUST00000055184.6
ENSMUST00000108551.2
Gp1ba

glycoprotein 1b, alpha polypeptide

chr7_+_43351378 15.248 ENSMUST00000012798.7
ENSMUST00000122423.1
ENSMUST00000121494.1
Siglec5


sialic acid binding Ig-like lectin 5


chr3_-_98893209 14.564 ENSMUST00000029464.7
Hao2
hydroxyacid oxidase 2
chr17_+_34914459 14.399 ENSMUST00000007249.8
Slc44a4
solute carrier family 44, member 4
chr5_-_24030297 14.332 ENSMUST00000101513.2
Fam126a
family with sequence similarity 126, member A
chr7_+_142498832 14.113 ENSMUST00000078497.8
ENSMUST00000105953.3
ENSMUST00000179658.1
ENSMUST00000105954.3
ENSMUST00000105952.3
ENSMUST00000105955.1
ENSMUST00000074187.6
ENSMUST00000180152.1
ENSMUST00000105950.4
ENSMUST00000105957.3
ENSMUST00000169299.2
ENSMUST00000105958.3
ENSMUST00000105949.1
Tnnt3












troponin T3, skeletal, fast












chr6_+_30541582 13.573 ENSMUST00000096066.4
Cpa2
carboxypeptidase A2, pancreatic
chr11_+_58948890 13.505 ENSMUST00000078267.3
Hist3h2ba
histone cluster 3, H2ba
chrX_-_107403295 13.476 ENSMUST00000033591.5
Itm2a
integral membrane protein 2A
chr3_+_103832562 13.139 ENSMUST00000062945.5
Bcl2l15
BCLl2-like 15
chr15_+_57985873 12.797 ENSMUST00000050374.2
Fam83a
family with sequence similarity 83, member A
chr9_+_107950952 12.724 ENSMUST00000049348.3
Traip
TRAF-interacting protein
chr2_+_84839395 12.434 ENSMUST00000146816.1
ENSMUST00000028469.7
Slc43a1

solute carrier family 43, member 1

chr4_-_41464816 12.049 ENSMUST00000108055.2
ENSMUST00000154535.1
ENSMUST00000030148.5
Kif24


kinesin family member 24


chr4_-_42874195 12.037 ENSMUST00000107978.1
ENSMUST00000055944.4
BC049635

cDNA sequence BC049635

chr1_-_173333503 11.901 ENSMUST00000038227.4
Darc
Duffy blood group, chemokine receptor
chr11_+_117782358 11.690 ENSMUST00000117781.1
Tmc8
transmembrane channel-like gene family 8
chr2_-_153241402 11.433 ENSMUST00000056924.7
Plagl2
pleiomorphic adenoma gene-like 2
chr11_+_117782076 11.364 ENSMUST00000127080.1
Tmc8
transmembrane channel-like gene family 8
chr11_+_117782281 11.214 ENSMUST00000050874.7
ENSMUST00000106334.2
Tmc8

transmembrane channel-like gene family 8

chr6_-_136857727 10.436 ENSMUST00000032341.2
Art4
ADP-ribosyltransferase 4
chr4_+_132974102 10.368 ENSMUST00000030693.6
Fgr
Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog
chr13_-_95525239 10.335 ENSMUST00000022185.8
F2rl1
coagulation factor II (thrombin) receptor-like 1
chr11_-_102469839 10.075 ENSMUST00000103086.3
Itga2b
integrin alpha 2b
chr2_-_153225396 9.512 ENSMUST00000099194.2
Tspyl3
TSPY-like 3
chr4_-_154928187 9.320 ENSMUST00000123514.1
Tnfrsf14
tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)
chr9_-_111057235 9.169 ENSMUST00000111888.1
Ccrl2
chemokine (C-C motif) receptor-like 2
chr8_-_77517898 8.860 ENSMUST00000076316.4
Arhgap10
Rho GTPase activating protein 10
chr17_-_29237759 8.825 ENSMUST00000137727.1
ENSMUST00000024805.7
Cpne5

copine V

chr14_+_44102654 8.644 ENSMUST00000074839.6
Ear2
eosinophil-associated, ribonuclease A family, member 2
chr15_-_34356421 8.569 ENSMUST00000179647.1
9430069I07Rik
RIKEN cDNA 9430069I07 gene
chr11_-_117782182 8.521 ENSMUST00000152304.1
Tmc6
transmembrane channel-like gene family 6
chr5_-_24030649 8.377 ENSMUST00000030849.6
Fam126a
family with sequence similarity 126, member A
chr4_+_155790439 8.176 ENSMUST00000165000.1
Ankrd65
ankyrin repeat domain 65
chr14_-_43923559 8.097 ENSMUST00000159175.1
Ear10
eosinophil-associated, ribonuclease A family, member 10
chr1_-_171649002 8.020 ENSMUST00000111276.3
Slamf7
SLAM family member 7
chr1_-_52232296 7.900 ENSMUST00000114512.1
Gls
glutaminase
chr17_-_33713372 7.898 ENSMUST00000173392.1
March2
membrane-associated ring finger (C3HC4) 2
chr14_-_43923368 7.865 ENSMUST00000163652.1
Ear10
eosinophil-associated, ribonuclease A family, member 10
chr1_-_181842334 7.647 ENSMUST00000005003.6
Lbr
lamin B receptor
chr5_+_138280538 7.582 ENSMUST00000162245.1
ENSMUST00000161691.1
Stag3

stromal antigen 3

chr5_+_115466234 7.482 ENSMUST00000145785.1
ENSMUST00000031495.4
ENSMUST00000112071.1
ENSMUST00000125568.1
Pla2g1b



phospholipase A2, group IB, pancreas



chr5_+_138280516 7.414 ENSMUST00000048028.8
Stag3
stromal antigen 3
chr3_-_14808358 7.283 ENSMUST00000181860.1
ENSMUST00000144327.2
Car1

carbonic anhydrase 1

chr6_+_125071277 7.267 ENSMUST00000140346.2
ENSMUST00000171989.1
Lpar5

lysophosphatidic acid receptor 5

chr7_+_97842917 6.992 ENSMUST00000033040.5
Pak1
p21 protein (Cdc42/Rac)-activated kinase 1
chr6_-_25809189 6.814 ENSMUST00000115327.1
Pot1a
protection of telomeres 1A
chr6_-_25809210 6.808 ENSMUST00000115330.1
ENSMUST00000115329.1
Pot1a

protection of telomeres 1A

chr7_-_81566939 6.764 ENSMUST00000042318.5
Fsd2
fibronectin type III and SPRY domain containing 2
chr2_+_5137756 6.588 ENSMUST00000027988.7
Ccdc3
coiled-coil domain containing 3
chr16_-_19983005 6.545 ENSMUST00000058839.8
Klhl6
kelch-like 6
chr3_+_79884576 6.411 ENSMUST00000145992.1
Fam198b
family with sequence similarity 198, member B
chr7_+_103937382 6.405 ENSMUST00000098189.1
Olfr632
olfactory receptor 632
chr15_+_78926720 6.396 ENSMUST00000089377.5
Lgals1
lectin, galactose binding, soluble 1
chr9_-_42399709 6.334 ENSMUST00000160940.1
Tecta
tectorin alpha
chr10_+_97565436 6.331 ENSMUST00000038160.4
Lum
lumican
chr11_+_70505244 6.228 ENSMUST00000019063.2
Tm4sf5
transmembrane 4 superfamily member 5
chr8_+_123117354 5.958 ENSMUST00000037900.8
Cpne7
copine VII
chrX_+_56447965 5.890 ENSMUST00000079663.6
Gm2174
predicted gene 2174
chrX_-_139085211 5.774 ENSMUST00000033626.8
ENSMUST00000060824.3
Serpina7

serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7

chr11_+_4986824 5.714 ENSMUST00000009234.9
ENSMUST00000109897.1
Ap1b1

adaptor protein complex AP-1, beta 1 subunit

chr19_-_29367294 5.497 ENSMUST00000138051.1
Plgrkt
plasminogen receptor, C-terminal lysine transmembrane protein
chr1_+_171559186 5.465 ENSMUST00000004829.7
Cd244
CD244 natural killer cell receptor 2B4
chr14_+_33954020 5.381 ENSMUST00000035695.8
Rbp3
retinol binding protein 3, interstitial
chr5_-_24351604 5.188 ENSMUST00000036092.7
Kcnh2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr14_-_78725089 5.172 ENSMUST00000074729.5
Dgkh
diacylglycerol kinase, eta
chr5_-_137116177 4.937 ENSMUST00000054384.5
ENSMUST00000152207.1
Trim56

tripartite motif-containing 56

chrX_-_139085230 4.933 ENSMUST00000152457.1
Serpina7
serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr11_-_78176619 4.915 ENSMUST00000148154.2
ENSMUST00000017549.6
Nek8

NIMA (never in mitosis gene a)-related expressed kinase 8

chr13_+_49682191 4.901 ENSMUST00000172254.1
Iars
isoleucine-tRNA synthetase
chr5_+_137630116 4.840 ENSMUST00000175968.1
Lrch4
leucine-rich repeats and calponin homology (CH) domain containing 4
chr2_-_102901346 4.827 ENSMUST00000111192.2
ENSMUST00000111190.2
ENSMUST00000111198.2
ENSMUST00000111191.2
ENSMUST00000060516.7
ENSMUST00000099673.2
ENSMUST00000005218.8
ENSMUST00000111194.1
Cd44







CD44 antigen







chr10_+_99443699 4.794 ENSMUST00000167243.1
Gad1-ps
glutamate decarboxylase 1, pseudogene
chr10_-_93891141 4.664 ENSMUST00000180840.1
Metap2
methionine aminopeptidase 2
chr4_-_56802265 4.544 ENSMUST00000030140.2
Ikbkap
inhibitor of kappa light polypeptide enhancer in B cells, kinase complex-associated protein
chr14_+_51129055 4.417 ENSMUST00000095923.3
Rnase6
ribonuclease, RNase A family, 6
chr15_-_74763567 4.318 ENSMUST00000040404.6
Ly6d
lymphocyte antigen 6 complex, locus D
chr4_-_32923455 4.246 ENSMUST00000035719.4
ENSMUST00000084749.1
Ankrd6

ankyrin repeat domain 6

chr17_+_27342453 4.187 ENSMUST00000151398.1
Gm10505
predicted gene 10505
chr19_+_29367447 4.088 ENSMUST00000016640.7
Cd274
CD274 antigen
chr10_-_129902726 3.897 ENSMUST00000071557.1
Olfr815
olfactory receptor 815
chr1_-_173912904 3.882 ENSMUST00000009340.8
Mnda
myeloid cell nuclear differentiation antigen
chr11_+_67200052 3.823 ENSMUST00000124516.1
ENSMUST00000018637.8
Myh1

myosin, heavy polypeptide 1, skeletal muscle, adult

chr4_+_56802337 3.792 ENSMUST00000045368.5
BC026590
cDNA sequence BC026590
chr11_+_94936224 3.789 ENSMUST00000001547.7
Col1a1
collagen, type I, alpha 1
chr6_+_29279587 3.758 ENSMUST00000167131.1
Fam71f2
family with sequence similarity 71, member F2
chr1_-_173535957 3.739 ENSMUST00000139092.1
BC094916
cDNA sequence BC094916
chr4_+_132535542 3.668 ENSMUST00000094657.3
ENSMUST00000105940.3
ENSMUST00000105939.3
ENSMUST00000150207.1
Dnajc8



DnaJ (Hsp40) homolog, subfamily C, member 8



chr17_-_7385305 3.658 ENSMUST00000070059.3
Gm9992
predicted gene 9992
chr1_-_167466780 3.599 ENSMUST00000036643.4
Lrrc52
leucine rich repeat containing 52
chr7_-_15999495 3.576 ENSMUST00000094821.3
Gltscr1
glioma tumor suppressor candidate region gene 1
chr10_+_116177351 3.551 ENSMUST00000155606.1
ENSMUST00000128399.1
Ptprr

protein tyrosine phosphatase, receptor type, R

chr3_+_98222148 3.519 ENSMUST00000029469.4
Reg4
regenerating islet-derived family, member 4
chr15_+_12205009 3.489 ENSMUST00000038172.8
Mtmr12
myotubularin related protein 12
chr3_+_79884496 3.466 ENSMUST00000118853.1
Fam198b
family with sequence similarity 198, member B
chr11_-_98625661 3.362 ENSMUST00000104933.1
Gm12355
predicted gene 12355
chr2_-_120731503 3.361 ENSMUST00000110701.1
ENSMUST00000110700.1
Cdan1

congenital dyserythropoietic anemia, type I (human)

chr14_+_76504185 3.325 ENSMUST00000177207.1
Tsc22d1
TSC22 domain family, member 1
chr11_+_50850685 3.182 ENSMUST00000171427.1
Grm6
glutamate receptor, metabotropic 6
chr9_-_32541589 3.157 ENSMUST00000016231.7
Fli1
Friend leukemia integration 1
chr9_+_66350465 3.100 ENSMUST00000042824.6
Herc1
hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain (RLD) 1
chr6_+_41302265 3.092 ENSMUST00000031913.4
Try4
trypsin 4
chr2_+_180499893 3.055 ENSMUST00000029084.2
Ntsr1
neurotensin receptor 1
chr19_-_46969474 2.930 ENSMUST00000086961.7
Nt5c2
5'-nucleotidase, cytosolic II
chr10_+_39133981 2.887 ENSMUST00000019991.7
Tube1
epsilon-tubulin 1
chr3_+_88621436 2.886 ENSMUST00000170653.2
ENSMUST00000177303.1
Arhgef2

rho/rac guanine nucleotide exchange factor (GEF) 2

chr10_-_128626464 2.804 ENSMUST00000026420.5
Rps26
ribosomal protein S26
chr14_+_22019833 2.760 ENSMUST00000159777.1
ENSMUST00000162540.1
1700112E06Rik

RIKEN cDNA 1700112E06 gene

chr1_-_160792908 2.667 ENSMUST00000028049.7
Rabgap1l
RAB GTPase activating protein 1-like
chr14_+_22019712 2.662 ENSMUST00000075639.4
ENSMUST00000161249.1
1700112E06Rik

RIKEN cDNA 1700112E06 gene

chr2_+_136891501 2.646 ENSMUST00000141463.1
Slx4ip
SLX4 interacting protein
chr6_+_47877204 2.644 ENSMUST00000061890.7
Zfp282
zinc finger protein 282
chr13_-_13393592 2.633 ENSMUST00000021738.8
Gpr137b
G protein-coupled receptor 137B
chr11_-_99322943 2.604 ENSMUST00000038004.2
Krt25
keratin 25
chr10_+_41887428 2.591 ENSMUST00000041438.6
Sesn1
sestrin 1
chr2_+_164746028 2.501 ENSMUST00000109327.3
Dnttip1
deoxynucleotidyltransferase, terminal, interacting protein 1
chr7_-_18992774 2.425 ENSMUST00000098778.2
Gm10676
predicted gene 10676
chrX_+_73757069 2.406 ENSMUST00000002079.6
Plxnb3
plexin B3
chr4_-_118179946 2.295 ENSMUST00000050288.8
ENSMUST00000106403.1
Kdm4a

lysine (K)-specific demethylase 4A

chr6_-_34317442 2.124 ENSMUST00000154655.1
ENSMUST00000102980.4
Akr1b3

aldo-keto reductase family 1, member B3 (aldose reductase)

chr9_-_62510498 2.002 ENSMUST00000164246.2
Coro2b
coronin, actin binding protein, 2B
chr17_+_16972910 1.920 ENSMUST00000071374.5
BC002059
cDNA sequence BC002059
chrX_-_134111852 1.917 ENSMUST00000033610.6
Nox1
NADPH oxidase 1
chr10_+_116177217 1.828 ENSMUST00000148731.1
Ptprr
protein tyrosine phosphatase, receptor type, R
chr13_+_107031963 1.790 ENSMUST00000095459.1
3830408C21Rik
RIKEN cDNA 3830408C21 gene
chr2_+_164745979 1.785 ENSMUST00000017443.7
ENSMUST00000109326.3
Dnttip1

deoxynucleotidyltransferase, terminal, interacting protein 1

chr2_-_6721606 1.683 ENSMUST00000150624.2
ENSMUST00000142941.1
ENSMUST00000100429.4
ENSMUST00000182879.1
Celf2



CUGBP, Elav-like family member 2



chr7_-_135528645 1.681 ENSMUST00000053716.7
Clrn3
clarin 3
chr5_+_29378604 1.656 ENSMUST00000181005.1
4632411P08Rik
RIKEN cDNA 4632411P08 gene
chr14_+_51162260 1.592 ENSMUST00000075648.3
Ear5
eosinophil-associated, ribonuclease A family, member 5
chr12_+_95692212 1.589 ENSMUST00000057324.3
Flrt2
fibronectin leucine rich transmembrane protein 2
chr5_-_134906726 1.563 ENSMUST00000047305.5
Wbscr28
Williams-Beuren syndrome chromosome region 28 (human)
chr9_-_60688118 1.555 ENSMUST00000114034.2
ENSMUST00000065603.5
Lrrc49

leucine rich repeat containing 49

chr2_+_127080252 1.547 ENSMUST00000142737.1
Blvra
biliverdin reductase A
chr17_+_34354787 1.477 ENSMUST00000178562.1
ENSMUST00000025198.7
Btnl2

butyrophilin-like 2

chr5_-_5265224 1.368 ENSMUST00000115450.1
Cdk14
cyclin-dependent kinase 14
chr2_+_136892168 1.346 ENSMUST00000099311.2
Slx4ip
SLX4 interacting protein
chr10_-_117224480 1.339 ENSMUST00000020382.6
Yeats4
YEATS domain containing 4
chr7_+_16875302 1.263 ENSMUST00000108493.1
Dact3
dapper homolog 3, antagonist of beta-catenin (xenopus)
chr15_+_85017138 1.227 ENSMUST00000023070.5
Upk3a
uroplakin 3A
chrX_-_134111708 1.124 ENSMUST00000159259.1
ENSMUST00000113275.3
Nox1

NADPH oxidase 1

chr4_-_59438633 1.123 ENSMUST00000040166.7
ENSMUST00000107544.1
Susd1

sushi domain containing 1

chr2_+_30061754 1.072 ENSMUST00000149578.1
ENSMUST00000102866.3
Set

SET nuclear oncogene

chr7_-_45896656 1.030 ENSMUST00000120299.1
Syngr4
synaptogyrin 4
chr10_+_33863935 0.995 ENSMUST00000092597.3
Sult3a1
sulfotransferase family 3A, member 1
chr4_-_43669141 0.974 ENSMUST00000056474.6
Fam221b
family with sequence similarity 221, member B
chr2_-_6721890 0.827 ENSMUST00000114927.2
Celf2
CUGBP, Elav-like family member 2
chr2_+_144033059 0.773 ENSMUST00000037722.2
ENSMUST00000110032.1
Banf2

barrier to autointegration factor 2

chrX_+_144153695 0.765 ENSMUST00000135687.1
A730046J19Rik
RIKEN cDNA A730046J19 gene
chr11_+_65807175 0.749 ENSMUST00000071465.2
ENSMUST00000018491.7
Zkscan6

zinc finger with KRAB and SCAN domains 6


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
14.9 119.0 GO:0015671 oxygen transport(GO:0015671)
8.5 50.8 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
7.9 23.8 GO:0036018 response to erythropoietin(GO:0036017) cellular response to erythropoietin(GO:0036018) erythropoietin-mediated signaling pathway(GO:0038162)
6.8 88.9 GO:0060586 multicellular organismal iron ion homeostasis(GO:0060586)
6.4 19.1 GO:0046462 monoacylglycerol metabolic process(GO:0046462)
5.2 20.9 GO:0045575 basophil activation(GO:0045575)
4.5 13.6 GO:0060382 regulation of DNA strand elongation(GO:0060382)
4.2 67.6 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
4.2 29.2 GO:0001955 blood vessel maturation(GO:0001955)
4.1 49.2 GO:0034242 negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
3.7 15.0 GO:0007066 female meiosis sister chromatid cohesion(GO:0007066)
3.7 22.2 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
3.7 29.6 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
3.6 14.4 GO:1900620 acetylcholine biosynthetic process(GO:0008292) thiamine pyrophosphate transport(GO:0030974) acetate ester biosynthetic process(GO:1900620)
3.6 10.7 GO:0033189 response to vitamin A(GO:0033189)
3.4 10.3 GO:1900135 positive regulation of eosinophil degranulation(GO:0043311) regulation of neutrophil mediated cytotoxicity(GO:0070948) regulation of neutrophil mediated killing of symbiont cell(GO:0070949) positive regulation of renin secretion into blood stream(GO:1900135) positive regulation of eosinophil activation(GO:1902568)
3.3 19.9 GO:0002317 plasma cell differentiation(GO:0002317)
3.3 33.1 GO:0030916 otic vesicle formation(GO:0030916)
3.1 27.8 GO:0032264 IMP salvage(GO:0032264)
2.9 65.9 GO:0038065 collagen-activated signaling pathway(GO:0038065)
2.6 33.9 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
2.5 7.5 GO:0044240 multicellular organismal lipid catabolic process(GO:0044240)
2.1 58.3 GO:0051016 barbed-end actin filament capping(GO:0051016)
2.1 16.6 GO:0002326 B cell lineage commitment(GO:0002326)
1.9 5.6 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
1.8 5.5 GO:0071613 granzyme B production(GO:0071613) regulation of granzyme B production(GO:0071661) positive regulation of granzyme B production(GO:0071663)
1.8 32.2 GO:0015816 glycine transport(GO:0015816)
1.8 40.6 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
1.7 19.8 GO:0072656 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718) maintenance of protein location in mitochondrion(GO:0072656)
1.5 24.3 GO:0006657 CDP-choline pathway(GO:0006657)
1.4 14.1 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
1.4 7.0 GO:0060244 amygdala development(GO:0021764) negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
1.3 18.7 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804)
1.3 15.9 GO:0019374 galactolipid metabolic process(GO:0019374)
1.3 34.3 GO:0032460 negative regulation of protein oligomerization(GO:0032460)
1.3 7.9 GO:0006543 glutamine catabolic process(GO:0006543)
1.3 38.1 GO:0051693 actin filament capping(GO:0051693)
1.3 5.2 GO:1902303 negative regulation of potassium ion export(GO:1902303)
1.1 62.6 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.9 5.4 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.9 18.9 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.8 145.5 GO:0090501 RNA phosphodiester bond hydrolysis(GO:0090501)
0.8 3.0 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.7 2.1 GO:0006059 hexitol metabolic process(GO:0006059)
0.7 15.7 GO:0042730 fibrinolysis(GO:0042730)
0.6 5.5 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.6 2.4 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593)
0.6 4.1 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.6 4.1 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.5 10.4 GO:0033008 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.5 14.6 GO:0042537 benzene-containing compound metabolic process(GO:0042537)
0.5 3.1 GO:0014054 positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
0.5 1.5 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.4 4.9 GO:0035330 regulation of hippo signaling(GO:0035330)
0.4 18.1 GO:0032094 response to food(GO:0032094)
0.4 4.5 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.4 4.7 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.4 7.3 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.4 2.9 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.4 27.4 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.4 4.2 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.3 12.4 GO:0015804 neutral amino acid transport(GO:0015804)
0.3 8.8 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.3 5.2 GO:0046473 phosphatidic acid metabolic process(GO:0046473)
0.3 5.8 GO:0035855 megakaryocyte development(GO:0035855)
0.3 4.8 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.3 2.9 GO:0046040 IMP metabolic process(GO:0046040)
0.3 6.5 GO:0002467 germinal center formation(GO:0002467)
0.2 22.7 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.2 3.0 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.2 45.9 GO:0007596 blood coagulation(GO:0007596)
0.2 10.4 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.2 8.9 GO:0071158 positive regulation of cell cycle arrest(GO:0071158)
0.2 5.7 GO:0048268 clathrin coat assembly(GO:0048268)
0.2 11.5 GO:0003009 skeletal muscle contraction(GO:0003009)
0.2 3.2 GO:0090280 positive regulation of calcium ion import(GO:0090280)
0.2 1.2 GO:0060157 urinary bladder development(GO:0060157)
0.2 1.6 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.2 1.5 GO:0042167 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.2 12.0 GO:0007019 microtubule depolymerization(GO:0007019)
0.2 2.6 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.2 21.1 GO:0030177 positive regulation of Wnt signaling pathway(GO:0030177)
0.2 11.4 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.2 0.5 GO:1904742 regulation of telomeric DNA binding(GO:1904742) positive regulation of protein localization to nucleolus(GO:1904751)
0.2 7.3 GO:0006730 one-carbon metabolic process(GO:0006730)
0.2 19.1 GO:0007586 digestion(GO:0007586)
0.1 3.1 GO:0021702 cerebellar Purkinje cell differentiation(GO:0021702)
0.1 17.9 GO:0031497 chromatin assembly(GO:0031497)
0.1 6.0 GO:0071277 cellular response to calcium ion(GO:0071277)
0.1 2.6 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.1 8.5 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.1 5.3 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.1 0.3 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.1 3.5 GO:1901998 toxin transport(GO:1901998)
0.1 1.3 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 2.8 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.1 1.3 GO:0010719 negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.0 0.5 GO:0051026 chiasma assembly(GO:0051026)
0.0 6.3 GO:0007605 sensory perception of sound(GO:0007605)
0.0 0.2 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.8 GO:0032814 regulation of natural killer cell activation(GO:0032814)
0.0 1.4 GO:0000086 G2/M transition of mitotic cell cycle(GO:0000086)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
14.9 119.0 GO:0005833 hemoglobin complex(GO:0005833)
7.5 22.6 GO:0034774 secretory granule lumen(GO:0034774) cytoplasmic vesicle lumen(GO:0060205)
6.3 38.1 GO:0032437 cuticular plate(GO:0032437)
5.8 58.3 GO:0008290 F-actin capping protein complex(GO:0008290)
3.7 15.0 GO:0000802 transverse filament(GO:0000802)
2.9 31.8 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
1.9 13.6 GO:0070187 shelterin complex(GO:0070187)
1.7 29.9 GO:0031143 pseudopodium(GO:0031143)
1.6 4.9 GO:0097543 ciliary inversin compartment(GO:0097543)
1.3 5.4 GO:0033165 interphotoreceptor matrix(GO:0033165)
1.3 5.2 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
1.3 3.8 GO:0005584 collagen type I trimer(GO:0005584)
1.1 15.9 GO:0042589 zymogen granule membrane(GO:0042589)
0.8 3.2 GO:0035841 new growing cell tip(GO:0035841)
0.8 3.1 GO:0032280 symmetric synapse(GO:0032280)
0.7 10.0 GO:0071437 invadopodium(GO:0071437)
0.7 2.1 GO:0097454 Schwann cell microvillus(GO:0097454)
0.7 15.3 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.6 4.5 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.6 11.5 GO:0005861 troponin complex(GO:0005861)
0.6 6.3 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.5 16.5 GO:0097228 sperm principal piece(GO:0097228)
0.4 7.6 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.4 16.6 GO:0000788 nuclear nucleosome(GO:0000788)
0.4 4.8 GO:0031258 lamellipodium membrane(GO:0031258)
0.4 62.7 GO:0032993 protein-DNA complex(GO:0032993)
0.4 5.6 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.3 18.9 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.3 8.8 GO:0044297 neuronal cell body(GO:0043025) cell body(GO:0044297)
0.3 1.2 GO:0120001 apical plasma membrane urothelial plaque(GO:0120001)
0.3 1.4 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.3 10.1 GO:0008305 integrin complex(GO:0008305)
0.2 40.9 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.2 2.6 GO:0061700 GATOR2 complex(GO:0061700)
0.2 71.0 GO:0009897 external side of plasma membrane(GO:0009897)
0.2 3.9 GO:0032982 myosin filament(GO:0032982)
0.2 11.0 GO:0005871 kinesin complex(GO:0005871)
0.1 33.1 GO:0031965 nuclear membrane(GO:0031965)
0.1 12.8 GO:0072562 blood microparticle(GO:0072562)
0.1 3.0 GO:0005721 pericentric heterochromatin(GO:0005721)
0.1 3.7 GO:0030131 clathrin adaptor complex(GO:0030131)
0.1 2.9 GO:0002102 podosome(GO:0002102)
0.1 112.9 GO:0005887 integral component of plasma membrane(GO:0005887)
0.1 10.5 GO:0016324 apical plasma membrane(GO:0016324)
0.1 3.7 GO:0045171 intercellular bridge(GO:0045171)
0.1 8.1 GO:0031225 anchored component of membrane(GO:0031225)
0.1 4.8 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 32.0 GO:0015629 actin cytoskeleton(GO:0015629)
0.1 94.2 GO:0031410 cytoplasmic vesicle(GO:0031410)
0.1 2.8 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 4.3 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 7.9 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 1.1 GO:0005811 lipid droplet(GO:0005811)
0.0 2.6 GO:0005882 intermediate filament(GO:0005882)
0.0 18.8 GO:0000790 nuclear chromatin(GO:0000790)
0.0 0.1 GO:1990111 spermatoproteasome complex(GO:1990111)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
14.9 119.0 GO:0005344 oxygen transporter activity(GO:0005344)
7.4 22.2 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
6.2 49.4 GO:0004687 myosin light chain kinase activity(GO:0004687)
4.9 24.3 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
4.5 13.6 GO:1990955 G-rich single-stranded DNA binding(GO:1990955)
3.6 14.6 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
3.4 17.0 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
3.3 102.6 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
3.1 27.8 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
3.1 33.9 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
2.7 31.8 GO:0038064 collagen receptor activity(GO:0038064)
2.6 10.4 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
2.6 10.3 GO:0015057 thrombin-activated receptor activity(GO:0015057)
2.3 32.2 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
2.2 19.8 GO:0008865 fructokinase activity(GO:0008865)
2.1 6.4 GO:0048030 disaccharide binding(GO:0048030)
2.1 16.6 GO:0070644 vitamin D response element binding(GO:0070644)
2.0 14.1 GO:0031013 calcium-dependent ATPase activity(GO:0030899) troponin I binding(GO:0031013)
2.0 10.1 GO:0070051 fibrinogen binding(GO:0070051)
1.7 67.6 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
1.3 7.9 GO:0004359 glutaminase activity(GO:0004359)
1.1 5.6 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
1.1 7.6 GO:0070087 chromo shadow domain binding(GO:0070087)
1.1 15.9 GO:0047372 acylglycerol lipase activity(GO:0047372)
1.0 49.2 GO:0050699 WW domain binding(GO:0050699)
1.0 145.9 GO:0004540 ribonuclease activity(GO:0004540)
0.9 7.3 GO:0004064 arylesterase activity(GO:0004064)
0.9 3.6 GO:0099103 channel activator activity(GO:0099103) potassium channel activator activity(GO:0099104)
0.9 5.2 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.8 7.5 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.7 10.4 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.7 52.1 GO:0030507 spectrin binding(GO:0030507)
0.7 12.8 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.6 4.5 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.6 3.0 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.6 9.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.5 4.8 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.5 30.5 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.5 3.2 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.4 2.6 GO:0070728 leucine binding(GO:0070728)
0.4 13.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.4 5.4 GO:0016918 retinal binding(GO:0016918)
0.4 1.5 GO:0004074 biliverdin reductase activity(GO:0004074)
0.4 5.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.3 12.4 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.3 2.1 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.3 9.3 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.3 2.4 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
0.3 5.5 GO:0042288 MHC class I protein binding(GO:0042288)
0.3 3.8 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.2 82.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.2 13.5 GO:0001540 amyloid-beta binding(GO:0001540)
0.2 28.3 GO:0017048 Rho GTPase binding(GO:0017048)
0.2 36.1 GO:0047485 protein N-terminus binding(GO:0047485)
0.2 17.7 GO:0004896 cytokine receptor activity(GO:0004896)
0.2 6.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.2 22.0 GO:0005178 integrin binding(GO:0005178)
0.2 3.0 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.2 2.9 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 17.3 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.1 3.5 GO:0030247 polysaccharide binding(GO:0030247)
0.1 4.7 GO:0008235 metalloexopeptidase activity(GO:0008235)
0.1 1.3 GO:0070097 delta-catenin binding(GO:0070097)
0.1 6.3 GO:0005518 collagen binding(GO:0005518)
0.1 12.0 GO:0003777 microtubule motor activity(GO:0003777)
0.1 0.5 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.1 4.3 GO:0031491 nucleosome binding(GO:0031491)
0.1 17.9 GO:0008301 DNA binding, bending(GO:0008301)
0.1 24.2 GO:0005096 GTPase activator activity(GO:0005096)
0.1 35.4 GO:0003779 actin binding(GO:0003779)
0.1 12.7 GO:0008047 enzyme activator activity(GO:0008047)
0.1 0.5 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 5.7 GO:0008565 protein transporter activity(GO:0008565)
0.0 11.2 GO:0030246 carbohydrate binding(GO:0030246)
0.0 10.8 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 3.5 GO:0019208 phosphatase regulator activity(GO:0019208)
0.0 5.4 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.4 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 14.2 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 22.3 GO:0008270 zinc ion binding(GO:0008270)
0.0 7.3 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 0.7 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.0 2.8 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 1.4 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 2.6 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 1.3 GO:0008022 protein C-terminus binding(GO:0008022)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 30.5 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
1.1 37.7 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.8 32.6 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.6 27.2 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.4 16.6 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.4 40.7 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.4 10.1 PID_INTEGRIN_CS_PATHWAY Integrin family cell surface interactions
0.4 97.1 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.4 13.2 PID_EPO_PATHWAY EPO signaling pathway
0.4 10.3 ST_GA12_PATHWAY G alpha 12 Pathway
0.3 4.8 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.3 18.9 PID_RHOA_PATHWAY RhoA signaling pathway
0.3 7.0 PID_EPHA2_FWD_PATHWAY EPHA2 forward signaling
0.2 5.6 ST_INTERLEUKIN_4_PATHWAY Interleukin 4 (IL-4) Pathway
0.2 19.8 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.2 6.4 PID_RAS_PATHWAY Regulation of Ras family activation
0.1 4.2 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.1 3.8 PID_INTEGRIN3_PATHWAY Beta3 integrin cell surface interactions
0.1 4.9 PID_FCER1_PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 2.9 PID_REELIN_PATHWAY Reelin signaling pathway
0.1 3.0 PID_RAC1_PATHWAY RAC1 signaling pathway
0.0 5.9 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 2.1 PID_P53_DOWNSTREAM_PATHWAY Direct p53 effectors

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
3.7 55.5 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
1.7 55.8 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
1.5 27.8 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
1.3 37.5 REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES Genes involved in Generation of second messenger molecules
1.1 44.6 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
1.0 24.3 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.8 27.9 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.8 33.1 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.6 6.3 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation
0.6 18.5 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.6 10.1 REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.5 4.8 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.5 4.1 REACTOME_PD1_SIGNALING Genes involved in PD-1 signaling
0.5 10.4 REACTOME_PLATELET_SENSITIZATION_BY_LDL Genes involved in Platelet sensitization by LDL
0.5 22.0 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.4 16.6 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.4 7.5 REACTOME_ACYL_CHAIN_REMODELLING_OF_PI Genes involved in Acyl chain remodelling of PI
0.4 7.9 REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.4 19.8 REACTOME_GLUCOSE_TRANSPORT Genes involved in Glucose transport
0.3 2.9 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM Genes involved in Abacavir transport and metabolism
0.3 37.7 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.2 5.6 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.2 15.0 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.2 9.3 REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY Genes involved in Costimulation by the CD28 family
0.2 25.3 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 27.1 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.1 5.2 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 2.4 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.1 2.8 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 2.7 REACTOME_LIPID_DIGESTION_MOBILIZATION_AND_TRANSPORT Genes involved in Lipid digestion, mobilization, and transport
0.0 0.5 REACTOME_MEIOSIS Genes involved in Meiosis
0.0 2.7 REACTOME_MRNA_SPLICING Genes involved in mRNA Splicing