Motif ID: Tbp

Z-value: 3.291


Transcription factors associated with Tbp:

Gene SymbolEntrez IDGene Name
Tbp ENSMUSG00000014767.10 Tbp

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tbpmm10_v2_chr17_+_15499888_154999600.501.8e-03Click!


Activity profile for motif Tbp.

activity profile for motif Tbp


Sorted Z-values histogram for motif Tbp

Sorted Z-values for motif Tbp



Network of associatons between targets according to the STRING database.



First level regulatory network of Tbp

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_-_36455378 41.307 ENSMUST00000068182.2
Stfa3
stefin A3
chr16_-_36367623 38.926 ENSMUST00000096089.2
BC100530
cDNA sequence BC100530
chr16_+_36184082 33.679 ENSMUST00000114858.1
Gm5483
predicted gene 5483
chr16_+_36156801 32.279 ENSMUST00000079184.4
Stfa2l1
stefin A2 like 1
chr16_+_36277145 30.437 ENSMUST00000042097.9
Stfa1
stefin A1
chr14_+_80000292 28.307 ENSMUST00000088735.3
Olfm4
olfactomedin 4
chr9_+_98490522 26.573 ENSMUST00000035029.2
Rbp2
retinol binding protein 2, cellular
chr11_+_87793470 26.450 ENSMUST00000020779.4
Mpo
myeloperoxidase
chr6_-_41314700 25.874 ENSMUST00000064324.5
Try5
trypsin 5
chr3_-_106167564 25.612 ENSMUST00000063062.8
Chi3l3
chitinase 3-like 3
chr3_-_90695706 24.842 ENSMUST00000069960.5
ENSMUST00000117167.1
S100a9

S100 calcium binding protein A9 (calgranulin B)

chr16_+_36210403 24.430 ENSMUST00000089628.3
Gm5416
predicted gene 5416
chr6_-_41377604 22.857 ENSMUST00000096003.5
Prss3
protease, serine, 3
chr3_-_106149761 21.621 ENSMUST00000149836.1
Chi3l3
chitinase 3-like 3
chr14_-_56102458 20.615 ENSMUST00000015583.1
Ctsg
cathepsin G
chr6_+_142298419 19.942 ENSMUST00000041993.2
Iapp
islet amyloid polypeptide
chr11_-_55185029 19.919 ENSMUST00000039305.5
Slc36a2
solute carrier family 36 (proton/amino acid symporter), member 2
chr11_-_99438143 19.605 ENSMUST00000017743.2
Krt20
keratin 20
chr9_-_67832325 17.671 ENSMUST00000054500.5
C2cd4a
C2 calcium-dependent domain containing 4A
chr7_-_103853199 17.505 ENSMUST00000033229.3
Hbb-y
hemoglobin Y, beta-like embryonic chain
chr3_-_20275659 16.476 ENSMUST00000011607.5
Cpb1
carboxypeptidase B1 (tissue)
chr1_+_134182404 15.571 ENSMUST00000153856.1
ENSMUST00000082060.3
ENSMUST00000133701.1
ENSMUST00000132873.1
Chi3l1



chitinase 3-like 1



chr1_+_134182150 15.312 ENSMUST00000156873.1
Chi3l1
chitinase 3-like 1
chr6_+_41354105 15.312 ENSMUST00000072103.5
Try10
trypsin 10
chr13_+_21717626 15.156 ENSMUST00000091754.2
Hist1h3h
histone cluster 1, H3h
chr11_-_102107822 14.081 ENSMUST00000177304.1
ENSMUST00000017455.8
Pyy

peptide YY

chr7_-_103843154 14.024 ENSMUST00000063957.4
Hbb-bh1
hemoglobin Z, beta-like embryonic chain
chr4_+_34893772 13.928 ENSMUST00000029975.3
ENSMUST00000135871.1
ENSMUST00000108130.1
Cga


glycoprotein hormones, alpha subunit


chr4_+_120666562 13.912 ENSMUST00000094814.4
Cited4
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
chr7_-_103813913 13.202 ENSMUST00000098192.3
Hbb-bt
hemoglobin, beta adult t chain
chr6_-_41035501 13.154 ENSMUST00000031931.5
2210010C04Rik
RIKEN cDNA 2210010C04 gene
chr14_+_56042123 12.908 ENSMUST00000015576.4
Mcpt2
mast cell protease 2
chr6_+_41392356 12.757 ENSMUST00000049079.7
Gm5771
predicted gene 5771
chr8_+_94179089 12.738 ENSMUST00000034215.6
Mt1
metallothionein 1
chr18_-_78123324 12.629 ENSMUST00000160292.1
ENSMUST00000091813.5
Slc14a1

solute carrier family 14 (urea transporter), member 1

chr2_-_114052804 12.403 ENSMUST00000090269.6
Actc1
actin, alpha, cardiac muscle 1
chr6_-_67535783 12.364 ENSMUST00000058178.4
Tacstd2
tumor-associated calcium signal transducer 2
chr3_+_103832562 12.179 ENSMUST00000062945.5
Bcl2l15
BCLl2-like 15
chr11_+_67277124 12.159 ENSMUST00000019625.5
Myh8
myosin, heavy polypeptide 8, skeletal muscle, perinatal
chr2_-_62483637 12.157 ENSMUST00000136686.1
ENSMUST00000102733.3
Gcg

glucagon

chr3_-_20242173 12.116 ENSMUST00000001921.1
Cpa3
carboxypeptidase A3, mast cell
chr7_-_45526146 11.827 ENSMUST00000167273.1
ENSMUST00000042105.8
Ppp1r15a

protein phosphatase 1, regulatory (inhibitor) subunit 15A

chr7_-_103827922 11.623 ENSMUST00000023934.6
ENSMUST00000153218.1
Hbb-bs

hemoglobin, beta adult s chain

chr17_-_31129602 11.357 ENSMUST00000024827.4
Tff3
trefoil factor 3, intestinal
chr10_+_43579161 10.973 ENSMUST00000058714.8
Cd24a
CD24a antigen
chr11_-_69948145 10.944 ENSMUST00000179298.1
ENSMUST00000018710.6
ENSMUST00000135437.1
ENSMUST00000141837.2
ENSMUST00000142500.1
Slc2a4




solute carrier family 2 (facilitated glucose transporter), member 4




chr6_+_4747306 10.457 ENSMUST00000175823.1
ENSMUST00000176204.1
ENSMUST00000166678.1
Peg10


paternally expressed 10


chr7_-_143502515 10.345 ENSMUST00000010904.4
Phlda2
pleckstrin homology-like domain, family A, member 2
chr15_-_101491509 10.130 ENSMUST00000023718.7
5430421N21Rik
RIKEN cDNA 5430421N21 gene
chr7_-_44532064 9.939 ENSMUST00000098483.2
ENSMUST00000035323.4
Spib

Spi-B transcription factor (Spi-1/PU.1 related)

chr11_-_99024179 9.932 ENSMUST00000068031.7
Top2a
topoisomerase (DNA) II alpha
chr11_+_76998595 9.839 ENSMUST00000108402.2
ENSMUST00000021195.4
Slc6a4

solute carrier family 6 (neurotransmitter transporter, serotonin), member 4

chr13_-_21780616 9.833 ENSMUST00000080511.2
Hist1h1b
histone cluster 1, H1b
chr11_-_102897123 9.820 ENSMUST00000067444.3
Gfap
glial fibrillary acidic protein
chr4_-_41098174 9.772 ENSMUST00000055327.7
Aqp3
aquaporin 3
chr11_-_120551126 9.756 ENSMUST00000026121.2
Ppp1r27
protein phosphatase 1, regulatory subunit 27
chr11_+_120949053 9.600 ENSMUST00000154187.1
ENSMUST00000100130.3
ENSMUST00000129473.1
ENSMUST00000168579.1
Slc16a3



solute carrier family 16 (monocarboxylic acid transporters), member 3



chr13_-_73700721 9.109 ENSMUST00000022048.5
Slc6a19
solute carrier family 6 (neurotransmitter transporter), member 19
chr2_-_164356067 9.055 ENSMUST00000165980.1
Slpi
secretory leukocyte peptidase inhibitor
chr8_-_105933832 9.031 ENSMUST00000034368.6
Ctrl
chymotrypsin-like
chr13_+_23763660 8.879 ENSMUST00000055770.1
Hist1h1a
histone cluster 1, H1a
chr11_-_100121558 8.767 ENSMUST00000007275.2
Krt13
keratin 13
chr6_-_87981482 8.753 ENSMUST00000056403.5
H1fx
H1 histone family, member X
chr2_-_164356507 8.671 ENSMUST00000109367.3
Slpi
secretory leukocyte peptidase inhibitor
chr11_-_102897146 8.551 ENSMUST00000077902.4
Gfap
glial fibrillary acidic protein
chr4_-_119658781 8.544 ENSMUST00000106309.2
ENSMUST00000044426.7
Guca2b

guanylate cyclase activator 2b (retina)

chr10_-_88605017 8.522 ENSMUST00000119185.1
ENSMUST00000121629.1
Mybpc1

myosin binding protein C, slow-type

chr19_-_3414464 8.492 ENSMUST00000025842.6
Gal
galanin
chr7_-_4812351 8.459 ENSMUST00000079496.7
Ube2s
ubiquitin-conjugating enzyme E2S
chr14_-_56062307 8.347 ENSMUST00000043249.8
Mcpt4
mast cell protease 4
chr8_+_84969824 8.281 ENSMUST00000125893.1
Prdx2
peroxiredoxin 2
chr2_+_119618717 8.230 ENSMUST00000028771.7
Nusap1
nucleolar and spindle associated protein 1
chr4_+_123282778 8.158 ENSMUST00000106243.1
ENSMUST00000106241.1
ENSMUST00000080178.6
Pabpc4


poly(A) binding protein, cytoplasmic 4


chr18_+_34625009 7.965 ENSMUST00000166044.1
Kif20a
kinesin family member 20A
chr8_+_84969767 7.852 ENSMUST00000109733.1
Prdx2
peroxiredoxin 2
chr13_+_23575753 7.799 ENSMUST00000105105.1
Hist1h3d
histone cluster 1, H3d
chr19_+_60755947 7.739 ENSMUST00000088237.4
Nanos1
nanos homolog 1 (Drosophila)
chr6_+_78425973 7.703 ENSMUST00000079926.5
Reg1
regenerating islet-derived 1
chr18_+_34624621 7.447 ENSMUST00000167161.1
Kif20a
kinesin family member 20A
chr11_-_100135928 7.335 ENSMUST00000107411.2
Krt15
keratin 15
chr8_+_84969587 7.241 ENSMUST00000109734.1
ENSMUST00000005292.8
Prdx2

peroxiredoxin 2

chr6_+_78370877 7.188 ENSMUST00000096904.3
Reg3b
regenerating islet-derived 3 beta
chr15_+_79895017 7.102 ENSMUST00000023054.7
Apobec3
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3
chr7_+_131032061 6.902 ENSMUST00000084509.3
Dmbt1
deleted in malignant brain tumors 1
chr7_-_16259185 6.838 ENSMUST00000168818.1
C5ar1
complement component 5a receptor 1
chr13_-_23745511 6.685 ENSMUST00000091752.2
Hist1h3c
histone cluster 1, H3c
chr15_-_101712891 6.654 ENSMUST00000023709.5
Krt5
keratin 5
chr13_+_23544052 6.613 ENSMUST00000075558.2
Hist1h3f
histone cluster 1, H3f
chr4_-_140810646 6.608 ENSMUST00000026377.2
Padi3
peptidyl arginine deiminase, type III
chr10_+_88091070 6.591 ENSMUST00000048621.7
Pmch
pro-melanin-concentrating hormone
chr18_+_36528145 6.469 ENSMUST00000074298.6
ENSMUST00000115694.2
Slc4a9

solute carrier family 4, sodium bicarbonate cotransporter, member 9

chr7_-_141655319 6.246 ENSMUST00000062451.7
Muc6
mucin 6, gastric
chr2_-_119618455 6.230 ENSMUST00000123818.1
Oip5
Opa interacting protein 5
chr6_-_78378851 6.158 ENSMUST00000089667.1
ENSMUST00000167492.1
Reg3d

regenerating islet-derived 3 delta

chr19_-_34255325 5.907 ENSMUST00000039631.8
Acta2
actin, alpha 2, smooth muscle, aorta
chr4_-_42853888 5.906 ENSMUST00000107979.1
Gm12429
predicted gene 12429
chr15_-_101694299 5.849 ENSMUST00000023788.6
Krt6a
keratin 6A
chr10_+_79777261 5.841 ENSMUST00000020575.4
Fstl3
follistatin-like 3
chr17_-_24251382 5.776 ENSMUST00000115390.3
Ccnf
cyclin F
chr1_-_134079114 5.725 ENSMUST00000020692.6
Btg2
B cell translocation gene 2, anti-proliferative
chr13_+_23752267 5.720 ENSMUST00000091703.2
Hist1h3b
histone cluster 1, H3b
chr7_-_109781538 5.524 ENSMUST00000033331.6
Nrip3
nuclear receptor interacting protein 3
chr3_-_92458715 5.469 ENSMUST00000058142.3
Sprr3
small proline-rich protein 3
chr8_+_15057646 5.432 ENSMUST00000033842.3
Myom2
myomesin 2
chr3_-_106219477 5.401 ENSMUST00000082219.5
Chi3l4
chitinase 3-like 4
chr6_-_72958097 5.377 ENSMUST00000114049.1
Tmsb10
thymosin, beta 10
chr11_-_115514374 5.317 ENSMUST00000021083.6
Hn1
hematological and neurological expressed sequence 1
chr15_-_98482683 5.314 ENSMUST00000023726.3
Lalba
lactalbumin, alpha
chr13_-_23762378 5.250 ENSMUST00000091701.2
Hist1h3a
histone cluster 1, H3a
chrX_+_164438039 5.222 ENSMUST00000033755.5
Asb11
ankyrin repeat and SOCS box-containing 11
chr6_-_125494754 5.202 ENSMUST00000032492.8
Cd9
CD9 antigen
chr7_-_30612731 5.182 ENSMUST00000006476.4
Upk1a
uroplakin 1A
chr9_+_121777607 5.124 ENSMUST00000098272.2
Klhl40
kelch-like 40
chr5_-_114823460 5.045 ENSMUST00000140374.1
ENSMUST00000100850.4
Gm20499
2610524H06Rik
predicted gene 20499
RIKEN cDNA 2610524H06 gene
chr11_-_100261021 5.040 ENSMUST00000080893.6
Krt17
keratin 17
chr6_-_113719880 5.030 ENSMUST00000064993.5
Ghrl
ghrelin
chrX_+_164140447 5.025 ENSMUST00000073973.4
Ace2
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
chr2_+_13573927 5.004 ENSMUST00000141365.1
ENSMUST00000028062.2
Vim

vimentin

chr4_-_132353605 4.958 ENSMUST00000155129.1
Rcc1
regulator of chromosome condensation 1
chrX_+_73774397 4.929 ENSMUST00000002081.5
Srpk3
serine/arginine-rich protein specific kinase 3
chr13_-_21783391 4.897 ENSMUST00000099704.3
Hist1h3i
histone cluster 1, H3i
chr11_+_82101836 4.766 ENSMUST00000000194.3
Ccl12
chemokine (C-C motif) ligand 12
chr8_-_13254154 4.722 ENSMUST00000033825.4
Adprhl1
ADP-ribosylhydrolase like 1
chr17_-_33824346 4.706 ENSMUST00000173879.1
ENSMUST00000166693.2
ENSMUST00000173019.1
ENSMUST00000087342.6
ENSMUST00000173844.1
Rps28




ribosomal protein S28




chr12_+_81631369 4.607 ENSMUST00000036116.5
Ttc9
tetratricopeptide repeat domain 9
chr13_+_21716385 4.592 ENSMUST00000070124.3
Hist1h2ai
histone cluster 1, H2ai
chr10_-_93589621 4.547 ENSMUST00000020203.6
Snrpf
small nuclear ribonucleoprotein polypeptide F
chr6_-_72958465 4.506 ENSMUST00000114050.1
Tmsb10
thymosin, beta 10
chr5_-_99978914 4.375 ENSMUST00000112939.3
ENSMUST00000171786.1
ENSMUST00000072750.6
ENSMUST00000019128.8
ENSMUST00000172361.1
Hnrnpd




heterogeneous nuclear ribonucleoprotein D




chr17_-_33955658 4.261 ENSMUST00000174609.2
ENSMUST00000008812.7
Rps18

ribosomal protein S18

chr6_+_48895243 4.240 ENSMUST00000031835.7
Aoc1
amine oxidase, copper-containing 1
chr13_-_23683941 4.234 ENSMUST00000171127.1
Hist1h2ac
histone cluster 1, H2ac
chr17_+_23726336 4.213 ENSMUST00000024701.7
Pkmyt1
protein kinase, membrane associated tyrosine/threonine 1
chr4_-_133967296 4.202 ENSMUST00000105893.1
Hmgn2
high mobility group nucleosomal binding domain 2
chr15_-_80083374 4.174 ENSMUST00000081650.7
Rpl3
ribosomal protein L3
chr5_+_76809964 4.118 ENSMUST00000120818.1
C530008M17Rik
RIKEN cDNA C530008M17 gene
chr11_+_3289880 4.065 ENSMUST00000110043.1
ENSMUST00000094471.3
Patz1

POZ (BTB) and AT hook containing zinc finger 1

chr11_-_33163072 4.039 ENSMUST00000093201.6
ENSMUST00000101375.4
ENSMUST00000109354.3
ENSMUST00000075641.3
Npm1



nucleophosmin 1



chr13_-_21787218 3.973 ENSMUST00000091751.2
Hist1h2an
histone cluster 1, H2an
chr9_-_95815389 3.968 ENSMUST00000119760.1
Pls1
plastin 1 (I-isoform)
chr15_-_101850778 3.887 ENSMUST00000023790.3
Krt1
keratin 1
chr19_+_55180799 3.882 ENSMUST00000025936.5
Tectb
tectorin beta
chr16_-_36131156 3.877 ENSMUST00000161638.1
ENSMUST00000096090.2
Csta

cystatin A

chr13_+_23581563 3.873 ENSMUST00000102968.1
Hist1h4d
histone cluster 1, H4d
chr11_-_57832142 3.775 ENSMUST00000036917.2
Hand1
heart and neural crest derivatives expressed transcript 1
chr6_-_112696604 3.769 ENSMUST00000113182.1
ENSMUST00000113180.1
ENSMUST00000068487.5
ENSMUST00000077088.4
Rad18



RAD18 homolog (S. cerevisiae)



chr13_-_23622502 3.649 ENSMUST00000062045.2
Hist1h1e
histone cluster 1, H1e
chr11_+_94936224 3.611 ENSMUST00000001547.7
Col1a1
collagen, type I, alpha 1
chr15_-_101680281 3.599 ENSMUST00000023786.5
Krt6b
keratin 6B
chr4_+_127021311 3.488 ENSMUST00000030623.7
Sfpq
splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)
chr3_-_92485886 3.450 ENSMUST00000054599.7
Sprr1a
small proline-rich protein 1A
chr2_+_167062934 3.409 ENSMUST00000125674.1
1500012F01Rik
RIKEN cDNA 1500012F01 gene
chr6_-_87672142 3.191 ENSMUST00000032130.2
ENSMUST00000065997.2
Aplf

aprataxin and PNKP like factor

chr9_+_95637601 3.173 ENSMUST00000015498.8
Pcolce2
procollagen C-endopeptidase enhancer 2
chr19_-_4283033 3.136 ENSMUST00000167215.1
ENSMUST00000056888.6
Ankrd13d

ankyrin repeat domain 13 family, member D

chr9_+_108508005 3.111 ENSMUST00000006838.8
ENSMUST00000134939.1
Qars

glutaminyl-tRNA synthetase

chr14_+_56017964 2.952 ENSMUST00000022836.4
Mcpt1
mast cell protease 1
chr1_+_63176818 2.946 ENSMUST00000129339.1
Eef1b2
eukaryotic translation elongation factor 1 beta 2
chr4_-_116627478 2.932 ENSMUST00000081182.4
ENSMUST00000030457.5
Nasp

nuclear autoantigenic sperm protein (histone-binding)

chr9_+_30942541 2.928 ENSMUST00000068135.6
Adamts8
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 8
chr13_-_113663670 2.927 ENSMUST00000054650.4
Hspb3
heat shock protein 3
chr8_+_94137197 2.881 ENSMUST00000034207.6
Mt4
metallothionein 4
chr19_-_53589067 2.857 ENSMUST00000095978.3
Nutf2-ps1
nuclear transport factor 2, pseudogene 1
chr17_+_24720063 2.844 ENSMUST00000170715.1
ENSMUST00000054289.6
ENSMUST00000146867.1
Rps2


ribosomal protein S2


chr13_-_23571151 2.814 ENSMUST00000102969.3
Hist1h2ae
histone cluster 1, H2ae
chr2_+_153918391 2.810 ENSMUST00000109760.1
Bpifb3
BPI fold containing family B, member 3
chr2_+_153938218 2.799 ENSMUST00000109757.1
Bpifb4
BPI fold containing family B, member 4
chr7_-_30457515 2.760 ENSMUST00000045817.7
Kirrel2
kin of IRRE like 2 (Drosophila)
chr9_+_44334685 2.759 ENSMUST00000052686.2
H2afx
H2A histone family, member X
chr17_-_80207299 2.758 ENSMUST00000063417.9
Srsf7
serine/arginine-rich splicing factor 7
chr19_+_8723478 2.755 ENSMUST00000180819.1
ENSMUST00000181422.1
Snhg1

small nucleolar RNA host gene (non-protein coding) 1

chr14_-_56778301 2.731 ENSMUST00000022507.5
ENSMUST00000163924.1
Pspc1

paraspeckle protein 1

chr2_+_152736244 2.727 ENSMUST00000038368.8
ENSMUST00000109824.1
Id1

inhibitor of DNA binding 1

chr11_-_106301801 2.722 ENSMUST00000103071.3
Gh
growth hormone
chr17_-_35074485 2.707 ENSMUST00000007259.3
Ly6g6d
lymphocyte antigen 6 complex, locus G6D
chr13_+_23574381 2.695 ENSMUST00000090776.4
Hist1h2ad
histone cluster 1, H2ad
chr10_+_79988584 2.689 ENSMUST00000004784.4
ENSMUST00000105374.1
Cnn2

calponin 2

chr10_-_40302186 2.665 ENSMUST00000099945.4
Amd1
S-adenosylmethionine decarboxylase 1
chr14_+_67745229 2.657 ENSMUST00000111095.2
Gnrh1
gonadotropin releasing hormone 1
chr14_+_68083853 2.640 ENSMUST00000022639.7
Nefl
neurofilament, light polypeptide
chr17_-_6827990 2.591 ENSMUST00000181895.1
Gm2885
predicted gene 2885
chr5_+_115559467 2.580 ENSMUST00000086519.5
Rplp0
ribosomal protein, large, P0
chr17_+_29032664 2.572 ENSMUST00000130216.1
Srsf3
serine/arginine-rich splicing factor 3
chr5_+_115559505 2.570 ENSMUST00000156359.1
ENSMUST00000152976.1
Rplp0

ribosomal protein, large, P0

chr9_+_55541148 2.566 ENSMUST00000034869.4
Isl2
insulin related protein 2 (islet 2)
chr10_-_128626464 2.562 ENSMUST00000026420.5
Rps26
ribosomal protein S26
chr9_-_88522876 2.561 ENSMUST00000180563.2
ENSMUST00000183030.1
ENSMUST00000182232.1
Snhg5


small nucleolar RNA host gene 5


chr7_-_142899985 2.561 ENSMUST00000000219.3
Th
tyrosine hydroxylase
chr8_-_13254068 2.558 ENSMUST00000168498.1
Adprhl1
ADP-ribosylhydrolase like 1
chr8_-_13254096 2.547 ENSMUST00000171619.1
Adprhl1
ADP-ribosylhydrolase like 1
chr18_-_36766198 2.504 ENSMUST00000061522.7
Dnd1
dead end homolog 1 (zebrafish)
chr8_-_70839720 2.455 ENSMUST00000002989.9
Arrdc2
arrestin domain containing 2
chr4_+_86930691 2.440 ENSMUST00000164590.1
Acer2
alkaline ceramidase 2
chr13_-_21750505 2.428 ENSMUST00000102983.1
Hist1h4k
histone cluster 1, H4k
chr12_+_85473883 2.415 ENSMUST00000021674.6
Fos
FBJ osteosarcoma oncogene
chr4_+_41966058 2.403 ENSMUST00000108026.2
Gm20938
predicted gene, 20938
chrX_+_74270812 2.400 ENSMUST00000008826.7
ENSMUST00000151702.1
ENSMUST00000074085.5
ENSMUST00000135690.1
Rpl10



ribosomal protein L10



chr4_-_116627921 2.394 ENSMUST00000030456.7
Nasp
nuclear autoantigenic sperm protein (histone-binding)
chr19_+_39113898 2.349 ENSMUST00000087234.2
Cyp2c66
cytochrome P450, family 2, subfamily c, polypeptide 66
chr14_-_79771305 2.347 ENSMUST00000039568.5
Pcdh8
protocadherin 8

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
8.8 26.4 GO:0002149 hypochlorous acid metabolic process(GO:0002148) hypochlorous acid biosynthetic process(GO:0002149)
8.3 24.8 GO:0070488 neutrophil aggregation(GO:0070488)
6.6 19.9 GO:0015828 tyrosine transport(GO:0015828)
4.5 13.5 GO:0051464 positive regulation of cortisol secretion(GO:0051464)
3.9 11.8 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
3.9 31.5 GO:0015671 oxygen transport(GO:0015671)
3.7 11.0 GO:0002842 positive regulation of T cell mediated immune response to tumor cell(GO:0002842)
3.4 10.3 GO:0060722 spongiotrophoblast cell proliferation(GO:0060720) cell proliferation involved in embryonic placenta development(GO:0060722)
3.3 26.6 GO:0006776 vitamin A metabolic process(GO:0006776)
3.3 9.8 GO:0090649 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
2.5 19.9 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
2.5 9.9 GO:0045091 regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
2.5 12.4 GO:0090191 negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191)
2.5 9.8 GO:0021941 negative regulation of cerebellar granule cell precursor proliferation(GO:0021941)
2.3 21.1 GO:0070944 neutrophil mediated killing of bacterium(GO:0070944)
2.3 18.4 GO:0010624 regulation of Schwann cell proliferation(GO:0010624)
2.2 6.6 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
2.1 8.5 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
2.0 4.0 GO:0006407 rRNA export from nucleus(GO:0006407)
2.0 25.5 GO:0002002 regulation of angiotensin levels in blood(GO:0002002)
1.9 23.4 GO:0002679 respiratory burst involved in defense response(GO:0002679)
1.9 5.8 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
1.8 12.7 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
1.8 12.6 GO:0071918 urea transmembrane transport(GO:0071918)
1.7 12.2 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
1.6 4.8 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
1.5 40.2 GO:0045109 intermediate filament organization(GO:0045109)
1.5 5.9 GO:1903116 positive regulation of actin filament-based movement(GO:1903116)
1.5 4.4 GO:1905663 response to rapamycin(GO:1901355) regulation of telomerase RNA reverse transcriptase activity(GO:1905661) positive regulation of telomerase RNA reverse transcriptase activity(GO:1905663)
1.5 46.5 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
1.4 9.8 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
1.3 5.3 GO:0046351 disaccharide biosynthetic process(GO:0046351)
1.3 6.6 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
1.3 24.6 GO:0033275 actin-myosin filament sliding(GO:0033275)
1.3 3.8 GO:0003218 cardiac left ventricle formation(GO:0003218)
1.2 7.2 GO:1903207 neuron death in response to hydrogen peroxide(GO:0036476) regulation of hydrogen peroxide-induced neuron death(GO:1903207) negative regulation of hydrogen peroxide-induced neuron death(GO:1903208)
1.2 3.5 GO:0048611 ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611)
1.0 6.2 GO:0061644 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641) protein localization to CENP-A containing chromatin(GO:0061644)
1.0 5.1 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
1.0 4.0 GO:1902896 terminal web assembly(GO:1902896)
1.0 9.6 GO:0035879 plasma membrane lactate transport(GO:0035879)
1.0 13.4 GO:0046884 follicle-stimulating hormone secretion(GO:0046884)
0.9 14.4 GO:0032096 negative regulation of response to food(GO:0032096)
0.9 1.8 GO:0015793 glycerol transport(GO:0015793)
0.9 2.7 GO:0006597 spermine biosynthetic process(GO:0006597)
0.9 14.0 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.9 5.2 GO:0030913 paranodal junction assembly(GO:0030913)
0.9 2.6 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.9 6.8 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.9 2.6 GO:0042414 epinephrine metabolic process(GO:0042414)
0.8 2.4 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.8 15.4 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.7 2.2 GO:0006589 octopamine biosynthetic process(GO:0006589) octopamine metabolic process(GO:0046333)
0.7 10.7 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.7 14.1 GO:1900153 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.7 5.2 GO:0016584 nucleosome positioning(GO:0016584)
0.6 3.2 GO:0090027 negative regulation of monocyte chemotaxis(GO:0090027)
0.6 8.2 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.6 2.3 GO:0032696 negative regulation of interleukin-13 production(GO:0032696)
0.5 3.2 GO:0051105 regulation of DNA ligation(GO:0051105) positive regulation of DNA ligation(GO:0051106)
0.5 3.6 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.5 7.1 GO:0010528 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.5 3.5 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.5 2.5 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.5 0.9 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.4 5.8 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.4 2.7 GO:2000354 regulation of ovarian follicle development(GO:2000354)
0.4 2.1 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.4 10.9 GO:1904659 glucose transmembrane transport(GO:1904659)
0.4 1.2 GO:1903279 regulation of calcium:sodium antiporter activity(GO:1903279)
0.4 55.6 GO:0007586 digestion(GO:0007586)
0.4 7.6 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.4 2.7 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074) negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.4 3.9 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.4 22.0 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.4 4.2 GO:0071280 cellular response to copper ion(GO:0071280)
0.4 1.1 GO:0006059 hexitol metabolic process(GO:0006059) inner medullary collecting duct development(GO:0072061)
0.4 1.1 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.4 6.9 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.4 1.4 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.3 10.0 GO:0031424 keratinization(GO:0031424)
0.3 3.6 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.3 2.1 GO:1904798 positive regulation of core promoter binding(GO:1904798)
0.3 2.3 GO:0036506 maintenance of unfolded protein(GO:0036506) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.3 9.3 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.3 2.0 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.3 12.8 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.2 1.5 GO:0042113 B cell activation(GO:0042113)
0.2 3.2 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.2 3.9 GO:0051984 positive regulation of chromosome segregation(GO:0051984)
0.2 0.7 GO:0021590 cerebellum maturation(GO:0021590) cerebellar Purkinje cell layer maturation(GO:0021691) cerebellar cortex maturation(GO:0021699)
0.2 1.7 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.2 1.3 GO:0021886 hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888)
0.2 11.0 GO:0043627 response to estrogen(GO:0043627)
0.2 1.5 GO:1905516 positive regulation of fertilization(GO:1905516) positive regulation of acrosome reaction(GO:2000344)
0.2 1.5 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.2 6.1 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.2 0.5 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.2 14.0 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.2 0.6 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
0.2 1.4 GO:0046688 response to copper ion(GO:0046688)
0.2 2.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.2 11.2 GO:0006334 nucleosome assembly(GO:0006334)
0.1 2.5 GO:0060965 negative regulation of gene silencing by miRNA(GO:0060965)
0.1 7.4 GO:0015804 neutral amino acid transport(GO:0015804)
0.1 0.6 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 6.1 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.1 5.0 GO:0051290 protein heterotetramerization(GO:0051290)
0.1 1.2 GO:0014807 regulation of somitogenesis(GO:0014807)
0.1 5.5 GO:0030225 macrophage differentiation(GO:0030225)
0.1 4.2 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.1 8.3 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512)
0.1 2.7 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.1 2.7 GO:0090031 positive regulation of steroid hormone biosynthetic process(GO:0090031)
0.1 0.6 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
0.1 1.8 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 12.6 GO:0006342 chromatin silencing(GO:0006342)
0.1 0.9 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.1 0.6 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
0.1 0.8 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.1 2.4 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.1 1.6 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 2.7 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.1 1.8 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1 8.2 GO:0061515 myeloid cell development(GO:0061515)
0.1 0.6 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.1 4.9 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.1 0.5 GO:0007000 nucleolus organization(GO:0007000)
0.1 0.5 GO:0051461 corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.1 7.3 GO:0098869 cellular oxidant detoxification(GO:0098869)
0.1 1.8 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.1 1.0 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 0.4 GO:1901911 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 0.7 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.1 2.4 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 1.2 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.1 0.6 GO:0060689 cell differentiation involved in salivary gland development(GO:0060689)
0.1 0.4 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 1.2 GO:0007625 grooming behavior(GO:0007625)
0.0 0.4 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 5.2 GO:0008584 male gonad development(GO:0008584) development of primary male sexual characteristics(GO:0046546)
0.0 1.5 GO:0019236 response to pheromone(GO:0019236)
0.0 2.1 GO:0003012 muscle system process(GO:0003012)
0.0 2.3 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.3 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 0.2 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 0.6 GO:0030823 regulation of cGMP metabolic process(GO:0030823)
0.0 0.4 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.3 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 2.0 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 1.2 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.0 2.6 GO:0051028 mRNA transport(GO:0051028)
0.0 3.7 GO:0007605 sensory perception of sound(GO:0007605)
0.0 0.9 GO:0021591 ventricular system development(GO:0021591)
0.0 2.1 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.0 0.7 GO:0009268 response to pH(GO:0009268)
0.0 1.6 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.3 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.1 GO:0042255 ribosome assembly(GO:0042255)
0.0 0.7 GO:0035690 cellular response to drug(GO:0035690)
0.0 1.4 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.8 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194) negative regulation of cyclase activity(GO:0031280)
0.0 0.1 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.1 GO:0006172 ADP biosynthetic process(GO:0006172)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
7.0 56.4 GO:0005833 hemoglobin complex(GO:0005833)
4.6 18.4 GO:0097450 astrocyte end-foot(GO:0097450)
2.6 26.4 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
1.8 28.3 GO:0042581 specific granule(GO:0042581)
1.3 5.2 GO:0120001 apical plasma membrane urothelial plaque(GO:0120001)
1.2 3.6 GO:0005584 collagen type I trimer(GO:0005584)
1.2 6.9 GO:0030670 phagocytic vesicle membrane(GO:0030670)
1.1 2.2 GO:0034774 secretory granule lumen(GO:0034774) cytoplasmic vesicle lumen(GO:0060205)
1.1 12.2 GO:0032982 myosin filament(GO:0032982)
1.0 36.4 GO:0000788 nuclear nucleosome(GO:0000788)
0.9 4.5 GO:0034715 U7 snRNP(GO:0005683) pICln-Sm protein complex(GO:0034715)
0.9 2.6 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.8 11.8 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.8 5.9 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.8 6.2 GO:0042382 paraspeckles(GO:0042382)
0.8 33.1 GO:0000786 nucleosome(GO:0000786)
0.7 3.5 GO:1990745 EARP complex(GO:1990745)
0.6 10.9 GO:0032593 insulin-responsive compartment(GO:0032593)
0.6 5.0 GO:0045098 type III intermediate filament(GO:0045098)
0.6 14.9 GO:0042588 zymogen granule(GO:0042588)
0.6 4.0 GO:1990357 terminal web(GO:1990357)
0.6 2.2 GO:0032021 NELF complex(GO:0032021)
0.5 14.0 GO:0005859 muscle myosin complex(GO:0005859)
0.5 1.6 GO:0071007 U2-type catalytic step 2 spliceosome(GO:0071007)
0.5 54.2 GO:0005882 intermediate filament(GO:0005882)
0.5 2.9 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.5 11.0 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.5 1.4 GO:0031074 nucleocytoplasmic transport complex(GO:0031074)
0.4 2.5 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.4 2.4 GO:0035976 transcription factor AP-1 complex(GO:0035976)
0.4 2.6 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009) pigment granule membrane(GO:0090741)
0.4 3.2 GO:0016012 sarcoglycan complex(GO:0016012)
0.3 8.6 GO:0005680 anaphase-promoting complex(GO:0005680)
0.3 2.3 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.3 16.6 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.3 2.7 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.3 2.1 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.3 1.1 GO:0097454 Schwann cell microvillus(GO:0097454)
0.3 4.0 GO:0031616 spindle pole centrosome(GO:0031616)
0.3 3.8 GO:0042405 nuclear inclusion body(GO:0042405)
0.2 6.2 GO:0010369 chromocenter(GO:0010369)
0.2 15.4 GO:0005871 kinesin complex(GO:0005871)
0.2 1.1 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.2 2.2 GO:0097208 alveolar lamellar body(GO:0097208)
0.2 6.9 GO:0001533 cornified envelope(GO:0001533)
0.2 0.6 GO:0072534 perineuronal net(GO:0072534)
0.2 3.1 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.2 1.9 GO:0045298 tubulin complex(GO:0045298)
0.2 0.6 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.2 2.8 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.2 11.9 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 8.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 10.7 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 1.2 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.1 34.4 GO:0030141 secretory granule(GO:0030141)
0.1 1.0 GO:0000812 Swr1 complex(GO:0000812)
0.1 2.0 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 4.2 GO:0005876 spindle microtubule(GO:0005876)
0.1 7.5 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 3.2 GO:0090734 site of double-strand break(GO:0035861) site of DNA damage(GO:0090734)
0.1 10.2 GO:0042641 actomyosin(GO:0042641)
0.1 0.5 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.1 0.4 GO:0005916 fascia adherens(GO:0005916)
0.1 4.9 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 11.4 GO:0000793 condensed chromosome(GO:0000793)
0.1 2.4 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 14.9 GO:0005774 vacuolar membrane(GO:0005774)
0.0 2.1 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 6.8 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 1.8 GO:0016459 myosin complex(GO:0016459)
0.0 10.1 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.7 GO:0005922 connexin complex(GO:0005922)
0.0 0.6 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 6.3 GO:0043209 myelin sheath(GO:0043209)
0.0 4.2 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.5 GO:0000242 pericentriolar material(GO:0000242)
0.0 8.8 GO:0043025 neuronal cell body(GO:0043025)
0.0 0.7 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 5.0 GO:0098794 postsynapse(GO:0098794)
0.0 20.4 GO:0000790 nuclear chromatin(GO:0000790)
0.0 20.0 GO:0030054 cell junction(GO:0030054)
0.0 0.4 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 10.6 GO:0005730 nucleolus(GO:0005730)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
14.1 56.4 GO:0031721 hemoglobin alpha binding(GO:0031721)
9.8 9.8 GO:0015254 glycerol channel activity(GO:0015254)
6.6 19.9 GO:0005302 L-tyrosine transmembrane transporter activity(GO:0005302)
3.3 9.8 GO:0005330 dopamine:sodium symporter activity(GO:0005330)
3.1 24.8 GO:0050786 Toll-like receptor 4 binding(GO:0035662) RAGE receptor binding(GO:0050786)
2.5 9.8 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
2.2 10.9 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
2.1 10.7 GO:0030250 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
2.1 12.6 GO:0015265 urea channel activity(GO:0015265)
2.0 9.9 GO:0004533 exoribonuclease H activity(GO:0004533)
2.0 27.5 GO:0016918 retinal binding(GO:0016918)
1.9 23.4 GO:0008430 selenium binding(GO:0008430)
1.8 7.1 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
1.8 5.3 GO:0004461 lactose synthase activity(GO:0004461)
1.7 6.8 GO:0001847 opsonin receptor activity(GO:0001847)
1.7 8.5 GO:0004966 galanin receptor activity(GO:0004966)
1.7 5.0 GO:0016608 growth hormone-releasing hormone activity(GO:0016608)
1.5 7.3 GO:0030280 structural constituent of epidermis(GO:0030280)
1.4 9.6 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
1.3 6.6 GO:0004668 protein-arginine deiminase activity(GO:0004668)
1.2 4.8 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
1.1 4.4 GO:0003721 telomerase RNA reverse transcriptase activity(GO:0003721)
1.1 53.4 GO:0031492 nucleosomal DNA binding(GO:0031492)
1.1 33.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
1.0 5.0 GO:1990254 keratin filament binding(GO:1990254)
0.9 1.8 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.9 2.6 GO:0034617 tetrahydrobiopterin binding(GO:0034617)
0.8 2.4 GO:0071633 dihydroceramidase activity(GO:0071633)
0.7 2.2 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.7 14.0 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.7 5.0 GO:0042289 MHC class II protein binding(GO:0042289)
0.6 9.4 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.6 14.3 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.5 3.8 GO:0000403 Y-form DNA binding(GO:0000403)
0.5 1.5 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.5 4.2 GO:0008131 primary amine oxidase activity(GO:0008131)
0.5 2.3 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.5 12.2 GO:0000146 microfilament motor activity(GO:0000146)
0.4 4.0 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.4 2.2 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.4 23.0 GO:0004601 peroxidase activity(GO:0004601)
0.4 1.3 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.4 5.8 GO:0048185 activin binding(GO:0048185)
0.4 2.7 GO:0019808 polyamine binding(GO:0019808)
0.4 1.8 GO:0008390 testosterone 16-alpha-hydroxylase activity(GO:0008390)
0.4 12.9 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.4 2.5 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.3 2.7 GO:0005131 growth hormone receptor binding(GO:0005131)
0.3 8.2 GO:0008143 poly(A) binding(GO:0008143)
0.3 2.0 GO:0004111 creatine kinase activity(GO:0004111)
0.3 6.5 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.3 4.2 GO:0008097 5S rRNA binding(GO:0008097)
0.3 9.8 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.3 2.7 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.3 107.3 GO:0008236 serine-type peptidase activity(GO:0008236)
0.3 1.4 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.3 3.6 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.3 17.4 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.3 11.7 GO:0003785 actin monomer binding(GO:0003785)
0.3 15.5 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.2 1.7 GO:0048495 Roundabout binding(GO:0048495)
0.2 5.7 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.2 1.3 GO:0051381 histamine receptor activity(GO:0004969) histamine binding(GO:0051381)
0.2 3.2 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.2 2.6 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.2 8.5 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.2 6.9 GO:0005044 scavenger receptor activity(GO:0005044)
0.2 1.1 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.2 5.5 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.2 3.6 GO:0016208 AMP binding(GO:0016208)
0.2 7.4 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.2 2.7 GO:0070628 proteasome binding(GO:0070628)
0.2 12.4 GO:0017022 myosin binding(GO:0017022)
0.1 0.6 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.1 8.1 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 15.4 GO:0003777 microtubule motor activity(GO:0003777)
0.1 12.1 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.1 17.7 GO:0005178 integrin binding(GO:0005178)
0.1 22.4 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 10.4 GO:0097110 scaffold protein binding(GO:0097110)
0.1 21.2 GO:0008301 DNA binding, bending(GO:0008301)
0.1 9.3 GO:0005179 hormone activity(GO:0005179)
0.1 1.5 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 1.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 1.8 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 1.6 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 1.2 GO:0070097 delta-catenin binding(GO:0070097)
0.1 0.7 GO:0097157 pre-mRNA intronic binding(GO:0097157) mRNA CDS binding(GO:1990715)
0.1 1.4 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 5.1 GO:0005507 copper ion binding(GO:0005507)
0.1 2.0 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.1 3.1 GO:0017091 AU-rich element binding(GO:0017091)
0.1 3.2 GO:0016504 peptidase activator activity(GO:0016504)
0.1 3.8 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.1 0.5 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1 1.8 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 2.4 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 2.0 GO:0043274 phospholipase binding(GO:0043274)
0.1 0.4 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.1 0.4 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 24.4 GO:0045296 cadherin binding(GO:0045296)
0.1 2.2 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.1 1.5 GO:0016503 pheromone receptor activity(GO:0016503)
0.1 2.3 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 3.2 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.7 GO:0005243 gap junction channel activity(GO:0005243)
0.0 2.8 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.1 GO:0001962 alpha-1,3-galactosyltransferase activity(GO:0001962)
0.0 1.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.9 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.9 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 1.8 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.6 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.9 GO:0070888 E-box binding(GO:0070888)
0.0 5.7 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 5.3 GO:0019903 protein phosphatase binding(GO:0019903)
0.0 10.2 GO:0005198 structural molecule activity(GO:0005198)
0.0 2.2 GO:0051087 chaperone binding(GO:0051087)
0.0 3.0 GO:0051015 actin filament binding(GO:0051015)
0.0 0.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 3.1 GO:0019838 growth factor binding(GO:0019838)
0.0 0.1 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.0 9.5 GO:0003682 chromatin binding(GO:0003682)
0.0 0.1 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.4 GO:0030276 clathrin binding(GO:0030276)
0.0 0.6 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 25.7 PID_IL23_PATHWAY IL23-mediated signaling events
0.5 24.5 PID_AURORA_B_PATHWAY Aurora B signaling
0.3 10.9 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.2 12.7 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.2 23.0 PID_RB_1PATHWAY Regulation of retinoblastoma protein
0.2 16.9 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network
0.2 3.6 PID_LYMPH_ANGIOGENESIS_PATHWAY VEGFR3 signaling in lymphatic endothelium
0.2 43.1 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 11.8 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.1 10.3 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.1 2.7 PID_IL3_PATHWAY IL3-mediated signaling events
0.1 8.0 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 12.2 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.1 3.2 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 4.3 PID_A6B1_A6B4_INTEGRIN_PATHWAY a6b1 and a6b4 Integrin signaling
0.1 2.8 PID_ATM_PATHWAY ATM pathway
0.1 2.6 PID_ATF2_PATHWAY ATF-2 transcription factor network
0.1 2.7 PID_AR_NONGENOMIC_PATHWAY Nongenotropic Androgen signaling
0.1 1.5 SA_B_CELL_RECEPTOR_COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 1.7 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.1 2.0 PID_INTEGRIN_A4B1_PATHWAY Alpha4 beta1 integrin signaling events
0.1 11.1 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 5.7 PID_P53_DOWNSTREAM_PATHWAY Direct p53 effectors
0.0 3.3 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 2.2 PID_P53_REGULATION_PATHWAY p53 pathway
0.0 0.6 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 1.2 PID_RHOA_PATHWAY RhoA signaling pathway
0.0 2.1 PID_CXCR4_PATHWAY CXCR4-mediated signaling events
0.0 2.6 PID_PDGFRB_PATHWAY PDGFR-beta signaling pathway
0.0 7.2 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 2.9 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.4 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.3 PID_P38_ALPHA_BETA_PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.6 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 17.2 REACTOME_HORMONE_LIGAND_BINDING_RECEPTORS Genes involved in Hormone ligand-binding receptors
1.5 24.0 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
1.0 51.7 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
1.0 20.6 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.8 9.7 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.7 10.9 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.7 11.9 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.6 9.6 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.6 15.4 REACTOME_KINESINS Genes involved in Kinesins
0.5 27.5 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.5 16.0 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.5 18.2 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.4 14.8 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.4 10.3 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.4 16.2 REACTOME_METABOLISM_OF_STEROID_HORMONES_AND_VITAMINS_A_AND_D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.4 4.5 REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.4 11.8 REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.3 18.6 REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 Genes involved in Nuclear signaling by ERBB4
0.3 16.6 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.3 6.8 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.3 4.2 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.3 4.8 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.2 3.6 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.2 5.9 REACTOME_MUSCLE_CONTRACTION Genes involved in Muscle contraction
0.2 10.6 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.2 2.4 REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 3.1 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 2.6 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.1 5.3 REACTOME_CLEAVAGE_OF_GROWING_TRANSCRIPT_IN_THE_TERMINATION_REGION_ Genes involved in Cleavage of Growing Transcript in the Termination Region
0.1 1.1 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1 1.2 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 1.7 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.1 2.1 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.1 2.1 REACTOME_G_ALPHA_I_SIGNALLING_EVENTS Genes involved in G alpha (i) signalling events
0.1 5.1 REACTOME_MRNA_SPLICING Genes involved in mRNA Splicing
0.1 7.0 REACTOME_LATE_PHASE_OF_HIV_LIFE_CYCLE Genes involved in Late Phase of HIV Life Cycle
0.1 0.5 REACTOME_RNA_POL_I_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.1 3.2 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.1 14.2 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1 2.4 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 0.6 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION_IN_TLR7_8_OR_9_SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1 1.5 REACTOME_REGULATION_OF_SIGNALING_BY_CBL Genes involved in Regulation of signaling by CBL
0.0 1.1 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 0.7 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.0 1.5 REACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 0.9 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 2.0 REACTOME_SIGNALING_BY_PDGF Genes involved in Signaling by PDGF
0.0 0.1 REACTOME_BINDING_AND_ENTRY_OF_HIV_VIRION Genes involved in Binding and entry of HIV virion
0.0 0.4 REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING Genes involved in Retrograde neurotrophin signalling