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GSE58827: Dynamics of the Mouse Liver

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Results for Tbx19

Z-value: 1.39

Motif logo

Transcription factors associated with Tbx19

Gene Symbol Gene ID Gene Info
ENSMUSG00000026572.5 T-box 19

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tbx19mm10_v2_chr1_-_165160773_165160781-0.702.1e-06Click!

Activity profile of Tbx19 motif

Sorted Z-values of Tbx19 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_60499332 17.20 ENSMUST00000135953.1
major urinary protein 1
chr3_+_138415484 16.98 ENSMUST00000161312.1
ENSMUST00000013458.8
alcohol dehydrogenase 4 (class II), pi polypeptide
chr19_-_40187277 10.33 ENSMUST00000051846.6
cytochrome P450, family 2, subfamily c, polypeptide 70
chr17_+_79626669 8.47 ENSMUST00000086570.1
RIKEN cDNA 4921513D11 gene
chr6_-_119467210 7.79 ENSMUST00000118120.1
wingless-related MMTV integration site 5B
chr17_+_36942910 7.00 ENSMUST00000040498.5
ring finger protein 39
chr3_+_94693556 6.71 ENSMUST00000090848.3
ENSMUST00000173981.1
ENSMUST00000173849.1
ENSMUST00000174223.1
selenium binding protein 2
chr19_+_41029275 6.63 ENSMUST00000051806.4
ENSMUST00000112200.1
deoxynucleotidyltransferase, terminal
chr14_-_66124482 6.28 ENSMUST00000070515.1
epoxide hydrolase 2, cytoplasmic
chr19_+_12633303 6.08 ENSMUST00000044976.5
glycine-N-acyltransferase
chr10_+_88459569 6.00 ENSMUST00000020252.3
ENSMUST00000125612.1
synaptonemal complex protein 3
chr10_-_24927444 5.60 ENSMUST00000020161.8
arginase, liver
chr16_+_48842552 5.46 ENSMUST00000023329.4
resistin like alpha
chr9_-_119157055 5.10 ENSMUST00000010795.4
acetyl-Coenzyme A acyltransferase 1B
chr14_+_66140919 4.98 ENSMUST00000022620.9
cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal)
chr4_+_155562348 4.53 ENSMUST00000030939.7
NAD kinase
chr11_+_101468164 4.41 ENSMUST00000001347.6
Rho family GTPase 2
chr17_+_26113286 3.80 ENSMUST00000025010.7
transmembrane protein 8 (five membrane-spanning domains)
chr1_-_72212249 3.76 ENSMUST00000048860.7
melanoregulin
chr11_-_46698962 3.73 ENSMUST00000109225.2
T cell immunoglobulin and mucin domain containing 2
chr6_+_90465287 3.73 ENSMUST00000113530.1
Kruppel-like factor 15
chr8_-_41133697 3.66 ENSMUST00000155055.1
ENSMUST00000059115.6
ENSMUST00000145860.1
mitochondrial tumor suppressor 1
chr6_+_129180613 3.58 ENSMUST00000032260.5
C-type lectin domain family 2, member d
chr10_-_93540016 3.29 ENSMUST00000016034.2
amidohydrolase domain containing 1
chr1_+_171419027 3.17 ENSMUST00000171362.1
thiosulfate sulfurtransferase (rhodanese)-like domain containing 1
chrM_+_9870 3.11 ENSMUST00000084013.1
mitochondrially encoded NADH dehydrogenase 4L
chrM_+_10167 3.07 ENSMUST00000082414.1
mitochondrially encoded NADH dehydrogenase 4
chr19_+_8837445 2.91 ENSMUST00000171649.1
Bernardinelli-Seip congenital lipodystrophy 2 homolog (human)
chr13_+_58806564 2.81 ENSMUST00000109838.2
neurotrophic tyrosine kinase, receptor, type 2
chr1_+_185332143 2.78 ENSMUST00000027916.6
ENSMUST00000151769.1
ENSMUST00000110965.1
bisphosphate 3'-nucleotidase 1
chr12_-_80968075 2.75 ENSMUST00000095572.4
solute carrier family 10 (sodium/bile acid cotransporter family), member 1
chr7_+_130936172 2.71 ENSMUST00000006367.7
HtrA serine peptidase 1
chr2_-_113758638 2.64 ENSMUST00000099575.3
gremlin 1
chr11_-_101171302 2.62 ENSMUST00000164474.1
ENSMUST00000043397.7
pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr9_-_103230262 2.53 ENSMUST00000165296.1
ENSMUST00000112645.1
ENSMUST00000166836.1
transferrin
predicted gene 20425
chr1_-_24612700 2.53 ENSMUST00000088336.1
predicted gene 10222
chr5_-_115484297 2.43 ENSMUST00000112067.1
sirtuin 4
chr14_-_55585250 2.36 ENSMUST00000022828.8
ER membrane protein complex subunit 9
chr17_+_34670535 2.36 ENSMUST00000168533.1
ENSMUST00000087399.4
tenascin XB
chr5_-_38491948 2.36 ENSMUST00000129099.1
solute carrier family 2 (facilitated glucose transporter), member 9
chr5_+_34525797 2.27 ENSMUST00000125817.1
ENSMUST00000067638.7
SH3-domain binding protein 2
chr4_-_12087912 2.24 ENSMUST00000050686.3
transmembrane protein 67
chr17_+_6978860 2.24 ENSMUST00000089119.5
ENSMUST00000179728.1
ribonuclease T2B
chr5_-_138996087 2.22 ENSMUST00000110897.1
platelet derived growth factor, alpha
chr3_-_88254706 2.18 ENSMUST00000171887.1
Rhesus blood group-associated B glycoprotein
chr9_+_108569885 2.13 ENSMUST00000019183.8
DALR anticodon binding domain containing 3
chr14_+_65666394 2.08 ENSMUST00000022610.8
scavenger receptor class A, member 5 (putative)
chr2_-_148046896 2.03 ENSMUST00000172928.1
ENSMUST00000047315.3
forkhead box A2
chr2_-_112368021 2.01 ENSMUST00000028551.3
ER membrane protein complex subunit 4
chr7_+_12927410 2.01 ENSMUST00000045870.4
RIKEN cDNA 2310014L17 gene
chr11_-_60046477 1.99 ENSMUST00000000310.7
ENSMUST00000102693.2
ENSMUST00000148512.1
phosphatidylethanolamine N-methyltransferase
chr7_+_105404568 1.98 ENSMUST00000033187.4
cyclic nucleotide gated channel alpha 4
chr15_+_31602106 1.95 ENSMUST00000042702.6
family with sequence similarity 173, member B
chr16_-_3908639 1.94 ENSMUST00000115859.1
RIKEN cDNA 1700037C18 gene
chrX_+_133908441 1.92 ENSMUST00000113304.1
sushi-repeat-containing protein, X-linked 2
chr7_-_140955960 1.91 ENSMUST00000081649.8
interferon induced transmembrane protein 2
chr13_-_52929640 1.81 ENSMUST00000120535.1
ENSMUST00000119311.1
ENSMUST00000021913.9
ENSMUST00000110031.3
AU RNA binding protein/enoyl-coenzyme A hydratase
chr7_+_143830077 1.81 ENSMUST00000141916.1
7-dehydrocholesterol reductase
chr3_-_30509462 1.78 ENSMUST00000173899.1
MDS1 and EVI1 complex locus
chrX_+_140664908 1.76 ENSMUST00000112990.1
ENSMUST00000112988.1
midline 2
chr1_+_59256906 1.76 ENSMUST00000160662.1
ENSMUST00000114248.2
cyclin-dependent kinase 15
chr17_+_25773769 1.75 ENSMUST00000134108.1
ENSMUST00000002350.4
nuclear prelamin A recognition factor-like
chr19_+_3958803 1.69 ENSMUST00000179433.1
RIKEN cDNA 1700055N04 gene
chr19_-_41206774 1.69 ENSMUST00000025986.7
ENSMUST00000169941.1
tolloid-like 2
chr19_-_11818806 1.68 ENSMUST00000075304.6
syntaxin 3
chr7_+_143830204 1.67 ENSMUST00000144034.1
ENSMUST00000143338.1
7-dehydrocholesterol reductase
chr11_+_72301613 1.66 ENSMUST00000151440.1
ENSMUST00000146233.1
ENSMUST00000140842.2
XIAP associated factor 1
chr7_+_48959089 1.63 ENSMUST00000183659.1
neuron navigator 2
chr17_+_56628118 1.60 ENSMUST00000112979.2
catsper channel auxiliary subunit delta
chr13_-_56482246 1.49 ENSMUST00000022019.3
interleukin 9
chr14_+_65666430 1.47 ENSMUST00000069226.6
scavenger receptor class A, member 5 (putative)
chr1_-_59094885 1.47 ENSMUST00000097080.3
amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 11 (human)
chrX_+_73787002 1.44 ENSMUST00000166518.1
signal sequence receptor, delta
chr7_-_80947765 1.44 ENSMUST00000026818.5
ENSMUST00000117383.1
ENSMUST00000119980.1
SEC11 homolog A (S. cerevisiae)
chr4_+_122836236 1.43 ENSMUST00000030412.4
ENSMUST00000121870.1
ENSMUST00000097902.4
palmitoyl-protein thioesterase 1
chr18_-_82406777 1.40 ENSMUST00000065224.6
galanin receptor 1
chr1_+_33719863 1.39 ENSMUST00000088287.3
RAB23, member RAS oncogene family
chr19_-_10920629 1.38 ENSMUST00000025641.1
zona pellucida glycoprotein 1
chrX_+_100428906 1.38 ENSMUST00000060241.2
OTU domain containing 6A
chr19_+_34290653 1.33 ENSMUST00000025691.5
ENSMUST00000112472.2
Fas (TNF receptor superfamily member 6)
chr13_-_67332525 1.30 ENSMUST00000168892.1
ENSMUST00000109735.2
zinc finger protein 595
chr10_-_86011833 1.27 ENSMUST00000105304.1
ENSMUST00000061699.5
BPI fold containing family C
chr1_-_39805311 1.27 ENSMUST00000171319.2
predicted gene 3646
chr7_+_28741968 1.26 ENSMUST00000094632.4
seryl-aminoacyl-tRNA synthetase 2
chr11_+_69326252 1.25 ENSMUST00000018614.2
potassium voltage-gated channel, shaker-related subfamily, beta member 3
chr16_-_92466081 1.19 ENSMUST00000060005.8
regulator of calcineurin 1
chr6_+_124808885 1.17 ENSMUST00000143040.1
ENSMUST00000052727.4
ENSMUST00000130160.1
splA/ryanodine receptor domain and SOCS box containing 2
chrX_+_32894625 1.16 ENSMUST00000179069.1
predicted gene, 21657
chr9_-_16378231 1.15 ENSMUST00000082170.5
FAT tumor suppressor homolog 3 (Drosophila)
chr9_+_18404418 1.15 ENSMUST00000164441.1
ENSMUST00000169398.1
upstream binding transcription factor, RNA polymerase I-like 1
chr2_+_176236860 1.13 ENSMUST00000166464.1
RIKEN cDNA 2210418O10 gene
chr4_+_143615003 1.13 ENSMUST00000105773.1
predicted gene 13083
chr9_+_58582397 1.12 ENSMUST00000176557.1
ENSMUST00000114121.4
ENSMUST00000177064.1
neuroplastin
chr4_-_84546284 1.12 ENSMUST00000177040.1
basonuclin 2
chr13_+_4771649 1.12 ENSMUST00000065956.3
predicted gene 5444
chr6_+_17749170 1.12 ENSMUST00000053148.7
ENSMUST00000115417.3
suppression of tumorigenicity 7
chrX_-_34161499 1.11 ENSMUST00000178219.1
predicted gene, 21681
chrX_+_31117674 1.10 ENSMUST00000179532.1
predicted gene, 21447
chr14_-_63543931 1.07 ENSMUST00000058679.5
myotubularin related protein 9
chr9_-_25151772 1.06 ENSMUST00000008573.7
HERPUD family member 2
chrX_+_32047829 1.06 ENSMUST00000178747.1
predicted gene, 21645
chrX_-_33956540 1.06 ENSMUST00000179466.1
predicted gene 2964
chr8_+_105225145 1.06 ENSMUST00000034361.3
RIKEN cDNA D230025D16 gene
chrX_+_133908418 1.02 ENSMUST00000033606.8
ENSMUST00000113303.1
ENSMUST00000165805.1
sushi-repeat-containing protein, X-linked 2
chr2_-_175067763 1.00 ENSMUST00000072895.3
ENSMUST00000109066.1
predicted gene 14393
chr9_-_57606234 0.95 ENSMUST00000045068.8
complexin 3
chr7_-_110844350 0.93 ENSMUST00000177462.1
ENSMUST00000176746.1
ENSMUST00000177236.1
ring finger protein 141
chr13_+_3538075 0.92 ENSMUST00000059515.6
guanosine diphosphate (GDP) dissociation inhibitor 2
chr14_+_53845234 0.89 ENSMUST00000103674.4
T cell receptor alpha variable 19
chrX_-_3443690 0.87 ENSMUST00000105020.1
predicted gene 14346
chr2_-_181135220 0.85 ENSMUST00000016491.7
potassium voltage-gated channel, subfamily Q, member 2
chr17_+_46646225 0.85 ENSMUST00000002844.7
ENSMUST00000113429.1
ENSMUST00000113430.1
mitochondrial ribosomal protein L2
chr16_-_45844303 0.84 ENSMUST00000036355.6
pleckstrin homology-like domain, family B, member 2
chr14_-_50870557 0.83 ENSMUST00000006444.7
telomerase associated protein 1
chr13_-_67332498 0.81 ENSMUST00000171466.1
zinc finger protein 595
chrX_+_3700233 0.81 ENSMUST00000105019.2
predicted gene 14345
chrX_-_33577346 0.81 ENSMUST00000105119.3
predicted gene 2913
chrX_+_32560055 0.81 ENSMUST00000178070.1
germ cell-less homolog 1 (Drosophila)-like
chrX_-_3752885 0.81 ENSMUST00000178621.1
predicted gene 14351
chrX_+_32278394 0.81 ENSMUST00000179991.1
predicted gene 2799
chr15_-_98379197 0.81 ENSMUST00000057386.5
olfactory receptor 283
chrX_+_4196576 0.79 ENSMUST00000105015.2
predicted gene 14347
chrX_-_31383918 0.79 ENSMUST00000178444.1
predicted gene 2777
chrX_+_4370636 0.79 ENSMUST00000105014.1
predicted gene 10922
chr2_-_177578199 0.78 ENSMUST00000108945.1
ENSMUST00000108943.1
predicted gene 14406
chr2_+_175010241 0.78 ENSMUST00000109069.1
ENSMUST00000109070.2
predicted gene 14444
chrX_-_3957002 0.78 ENSMUST00000105017.3
predicted gene 3701
chrX_+_33313338 0.78 ENSMUST00000180039.1
predicted gene 2863
chrX_+_32973897 0.78 ENSMUST00000179538.1
predicted gene 2825
chrX_-_4291245 0.78 ENSMUST00000179325.1
predicted gene 10921
chr5_-_121191365 0.78 ENSMUST00000100770.2
ENSMUST00000054547.7
protein tyrosine phosphatase, non-receptor type 11
chr15_-_36140393 0.76 ENSMUST00000172831.1
regulator of G-protein signalling 22
chr1_+_127868773 0.75 ENSMUST00000037649.5
RAB3 GTPase activating protein subunit 1
chrX_+_32726137 0.75 ENSMUST00000179585.1
predicted gene, 21951
chr6_+_86195214 0.74 ENSMUST00000032066.9
transforming growth factor alpha
chrX_+_33657172 0.74 ENSMUST00000177912.1
predicted gene 2927
chr16_-_44746278 0.74 ENSMUST00000161436.1
GTP-binding protein 8 (putative)
chrX_+_14211148 0.72 ENSMUST00000079952.2
predicted gene 5382
chr3_-_88372740 0.72 ENSMUST00000107543.1
ENSMUST00000107542.1
bone gamma-carboxyglutamate protein 3
chr2_+_153875045 0.72 ENSMUST00000028983.2
BPI fold containing family B, member 2
chr6_+_41302265 0.69 ENSMUST00000031913.4
trypsin 4
chrX_-_33702349 0.68 ENSMUST00000105117.2
predicted gene 2933
chr16_-_44746337 0.67 ENSMUST00000023348.4
ENSMUST00000162512.1
GTP-binding protein 8 (putative)
chr14_-_56120623 0.67 ENSMUST00000089549.6
granzyme E
chr8_+_129072644 0.67 ENSMUST00000148234.1
RIKEN cDNA 1700008F21 gene
chr9_-_6266544 0.65 ENSMUST00000051706.4
DDI1, DNA-damage inducible 1, homolog 1 (S. cerevisiae)
chr11_-_69920892 0.63 ENSMUST00000152589.1
ENSMUST00000108612.1
ENSMUST00000108611.1
eukaryotic translation initiation factor 5A
chr1_+_15712303 0.61 ENSMUST00000170146.1
potassium voltage gated channel, Shab-related subfamily, member 2
chr1_-_164935522 0.61 ENSMUST00000027860.7
chemokine (C motif) ligand 1
chr15_-_100403243 0.60 ENSMUST00000124324.1
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr18_+_37484955 0.58 ENSMUST00000053856.4
protocadherin beta 17
chr15_-_101869695 0.57 ENSMUST00000087996.5
keratin 77
chr9_-_57467985 0.55 ENSMUST00000046587.6
secretory carrier membrane protein 5
chr1_+_183388981 0.55 ENSMUST00000097043.5
TATA box binding protein (Tbp)-associated factor, RNA polymerase I, A
chr7_-_134364859 0.54 ENSMUST00000172947.1
DNA segment, Chr 7, ERATO Doi 443, expressed
chr17_+_13234871 0.54 ENSMUST00000059824.6
sperm motility kinase 2B
chr5_-_143527977 0.52 ENSMUST00000100489.3
ENSMUST00000080537.7
RAS-related C3 botulinum substrate 1
chr2_+_177080256 0.50 ENSMUST00000134614.1
ENSMUST00000108968.1
predicted gene 14401
chr5_+_96173940 0.49 ENSMUST00000048361.8
predicted gene 2840
chr6_+_42286709 0.49 ENSMUST00000163936.1
chloride channel 1
chr7_-_132599637 0.49 ENSMUST00000054562.3
NK1 transcription factor related, locus 2 (Drosophila)
chr11_+_49340534 0.48 ENSMUST00000062719.1
olfactory receptor 1390
chr2_+_181991226 0.45 ENSMUST00000071760.6
predicted gene 14496
chr19_+_59219648 0.41 ENSMUST00000065204.6
potassium channel, subfamily K, member 18
chr11_-_115322025 0.39 ENSMUST00000103037.4
Usher syndrome 1G
chr1_+_159232299 0.36 ENSMUST00000076894.5
ring finger and WD repeat domain 2
chr7_+_22412231 0.34 ENSMUST00000177774.1
vomeronasal 1 receptor 148
chr4_-_144274027 0.33 ENSMUST00000105752.3
preferentially expressed antigen in melanoma like 5
chr5_-_129704259 0.33 ENSMUST00000042266.6
septin 14
chr1_-_78488846 0.31 ENSMUST00000068333.7
ENSMUST00000170217.1
phenylalanyl-tRNA synthetase, beta subunit
chrX_+_11305655 0.30 ENSMUST00000178806.1
predicted gene 14477
chr12_-_58269162 0.28 ENSMUST00000062254.2
C-type lectin domain family 14, member a
chr12_-_98259416 0.26 ENSMUST00000021390.7
galactosylceramidase
chr13_-_74376566 0.24 ENSMUST00000091481.2
zinc finger protein 72
chr9_-_124440899 0.24 ENSMUST00000180233.1
predicted gene, 20783
chr3_-_97610156 0.23 ENSMUST00000029730.4
chromodomain helicase DNA binding protein 1-like
chr3_-_153944632 0.22 ENSMUST00000072697.6
acyl-Coenzyme A dehydrogenase, medium chain
chr6_-_54593139 0.22 ENSMUST00000046520.6
FK506 binding protein 14
chr17_-_33216351 0.21 ENSMUST00000112162.3
predicted gene 4461
chr8_-_4275886 0.18 ENSMUST00000003029.7
translocase of inner mitochondrial membrane 44
chr2_-_177324307 0.18 ENSMUST00000108959.2
predicted gene 14412
chr15_+_31276491 0.17 ENSMUST00000068987.5
family with sequence similarity 136, member B, pseudogene
chr13_-_21453714 0.15 ENSMUST00000032820.7
ENSMUST00000110485.1
zinc finger and SCAN domain containing 26
chr4_+_43384332 0.15 ENSMUST00000136360.1
RUN and SH3 domain containing 2
chr7_+_17713233 0.13 ENSMUST00000081907.6
carcinoembryonic antigen-related cell adhesion molecule 5
chr1_+_156838915 0.10 ENSMUST00000111720.1
angiopoietin-like 1
chr9_+_58582240 0.09 ENSMUST00000177292.1
ENSMUST00000085651.5
neuroplastin
chr2_+_88817173 0.08 ENSMUST00000072057.1
olfactory receptor 1202
chr7_-_5014645 0.06 ENSMUST00000165320.1
Flt3 interacting zinc finger protein 1
chr14_-_52036143 0.05 ENSMUST00000052560.4
olfactory receptor 221
chr1_-_57406443 0.01 ENSMUST00000160837.1
ENSMUST00000161780.1
tRNA-yW synthesizing protein 5
chr5_-_45856496 0.00 ENSMUST00000087164.3
ENSMUST00000121573.1
ligand dependent nuclear receptor corepressor-like
chr9_+_15520830 0.00 ENSMUST00000178999.1
single-pass membrane protein with coiled-coil domains 4

Network of associatons between targets according to the STRING database.

First level regulatory network of Tbx19

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.2 17.0 GO:0006069 ethanol oxidation(GO:0006069)
2.1 6.3 GO:0046271 phenylpropanoid catabolic process(GO:0046271) olefin metabolic process(GO:1900673)
1.6 17.2 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
1.5 6.0 GO:0000711 meiotic DNA repair synthesis(GO:0000711) female meiosis sister chromatid cohesion(GO:0007066)
1.4 5.6 GO:0043091 L-arginine import(GO:0043091) arginine import(GO:0090467)
1.2 3.5 GO:0016132 brassinosteroid metabolic process(GO:0016131) brassinosteroid biosynthetic process(GO:0016132)
0.9 2.6 GO:1900157 regulation of bone mineralization involved in bone maturation(GO:1900157)
0.8 4.5 GO:0006741 NADP biosynthetic process(GO:0006741)
0.7 2.2 GO:0010512 negative regulation of phosphatidylinositol biosynthetic process(GO:0010512)
0.7 2.0 GO:0045013 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.7 3.3 GO:0006548 histidine catabolic process(GO:0006548)
0.5 2.2 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.5 2.4 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.5 1.4 GO:1990168 protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)
0.5 2.7 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.4 1.3 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.4 3.6 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.4 4.3 GO:0097286 iron ion import(GO:0097286)
0.4 2.8 GO:0099550 trans-synaptic signalling, modulating synaptic transmission(GO:0099550)
0.3 1.6 GO:0021564 vagus nerve development(GO:0021564)
0.3 2.5 GO:0097460 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447) ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.3 2.7 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.3 8.8 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.3 0.8 GO:2000850 negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.3 2.0 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.2 1.7 GO:0032364 oxygen homeostasis(GO:0032364)
0.2 1.0 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.2 4.4 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.2 1.2 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.2 1.4 GO:0098734 protein depalmitoylation(GO:0002084) positive regulation of pinocytosis(GO:0048549) macromolecule depalmitoylation(GO:0098734)
0.2 3.6 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.2 2.4 GO:0048251 elastic fiber assembly(GO:0048251)
0.2 1.7 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.2 1.7 GO:0098881 synaptic vesicle docking(GO:0016081) exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.2 0.6 GO:2000563 immunoglobulin production in mucosal tissue(GO:0002426) granzyme B production(GO:0071613) regulation of granzyme B production(GO:0071661) positive regulation of granzyme B production(GO:0071663) positive regulation of thymocyte migration(GO:2000412) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538) regulation of T-helper 1 cell cytokine production(GO:2000554) positive regulation of T-helper 1 cell cytokine production(GO:2000556) positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563) positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
0.2 2.9 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.2 6.6 GO:0033198 response to ATP(GO:0033198)
0.2 1.3 GO:0036337 Fas signaling pathway(GO:0036337)
0.2 2.2 GO:0046606 negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.2 3.1 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.2 3.7 GO:0072112 renal filtration cell differentiation(GO:0061318) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.2 1.8 GO:0035372 protein localization to microtubule(GO:0035372)
0.2 3.8 GO:0042640 anagen(GO:0042640)
0.1 5.0 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.1 2.4 GO:0046415 urate metabolic process(GO:0046415)
0.1 9.6 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.1 2.9 GO:0034389 lipid particle organization(GO:0034389)
0.1 0.8 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1 1.8 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.1 3.1 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.1 0.6 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1 1.4 GO:0006968 cellular defense response(GO:0006968)
0.1 0.8 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.1 1.9 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.1 1.4 GO:0006465 signal peptide processing(GO:0006465)
0.1 2.8 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.1 0.3 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.1 1.2 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.1 0.5 GO:0032667 interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667)
0.1 1.5 GO:0032754 positive regulation of interleukin-5 production(GO:0032754)
0.1 1.4 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.1 3.1 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.1 1.1 GO:0043586 tongue development(GO:0043586)
0.1 0.2 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 1.6 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.5 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.7 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 6.1 GO:0009636 response to toxic substance(GO:0009636)
0.0 0.3 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 1.1 GO:0010842 retina layer formation(GO:0010842)
0.0 0.4 GO:0050957 equilibrioception(GO:0050957)
0.0 1.1 GO:0001832 blastocyst growth(GO:0001832)
0.0 0.2 GO:0044789 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0 1.7 GO:0035456 response to interferon-beta(GO:0035456)
0.0 0.5 GO:0035404 histone-serine phosphorylation(GO:0035404)
0.0 0.4 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.5 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 1.1 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 0.6 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.0 0.9 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 3.3 GO:0007608 sensory perception of smell(GO:0007608)
0.0 0.7 GO:0019835 cytolysis(GO:0019835)
0.0 0.8 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.9 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 5.1 GO:0006631 fatty acid metabolic process(GO:0006631)
0.0 2.7 GO:0006814 sodium ion transport(GO:0006814)
0.0 0.2 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.5 GO:0006360 transcription from RNA polymerase I promoter(GO:0006360)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 6.0 GO:0000802 transverse filament(GO:0000802)
0.3 1.7 GO:0097361 CIA complex(GO:0097361)
0.3 1.7 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.3 2.5 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.3 4.4 GO:0072546 ER membrane protein complex(GO:0072546)
0.3 1.4 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.2 5.0 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.2 2.0 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.2 1.3 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.2 2.4 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.2 1.4 GO:0005787 signal peptidase complex(GO:0005787)
0.2 1.6 GO:0036128 CatSper complex(GO:0036128)
0.2 3.5 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 2.2 GO:0036038 MKS complex(GO:0036038)
0.1 0.6 GO:0070826 paraferritin complex(GO:0070826)
0.1 0.5 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.1 6.6 GO:0000791 euchromatin(GO:0000791)
0.1 0.3 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.1 2.2 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 6.2 GO:0070469 respiratory chain(GO:0070469)
0.1 1.6 GO:0005614 interstitial matrix(GO:0005614)
0.1 2.8 GO:0048786 presynaptic active zone(GO:0048786)
0.1 0.8 GO:0045180 basal cortex(GO:0045180)
0.1 11.4 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 2.2 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.5 GO:0060091 kinocilium(GO:0060091)
0.0 6.7 GO:0001650 fibrillar center(GO:0001650)
0.0 0.8 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.7 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 1.0 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 5.6 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 1.4 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 4.4 GO:0005769 early endosome(GO:0005769)
0.0 3.2 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 2.0 GO:0031526 brush border membrane(GO:0031526)
0.0 0.4 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 24.9 GO:0009986 cell surface(GO:0009986)
0.0 2.7 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.6 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 1.1 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 3.8 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.5 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.6 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 1.8 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 22.7 GO:0005615 extracellular space(GO:0005615)
0.0 0.8 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 2.7 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 2.8 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.5 GO:0034707 chloride channel complex(GO:0034707)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
5.7 17.2 GO:0005186 insulin-activated receptor activity(GO:0005009) pheromone activity(GO:0005186)
5.7 17.0 GO:0003960 NADPH:quinone reductase activity(GO:0003960) alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
1.5 6.1 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
1.5 7.3 GO:0070287 ferritin receptor activity(GO:0070287)
1.3 6.3 GO:0004301 epoxide hydrolase activity(GO:0004301)
1.2 3.5 GO:0047598 sterol delta7 reductase activity(GO:0009918) 7-dehydrocholesterol reductase activity(GO:0047598)
0.7 2.8 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441)
0.7 2.6 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.6 6.7 GO:0008430 selenium binding(GO:0008430)
0.5 5.6 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.5 3.3 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.5 2.8 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.4 1.3 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.4 1.3 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.4 2.7 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.4 2.5 GO:0072510 signal recognition particle binding(GO:0005047) ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.3 5.1 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.3 2.0 GO:0005223 intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223)
0.3 5.0 GO:0042166 acetylcholine binding(GO:0042166)
0.3 8.7 GO:0070330 aromatase activity(GO:0070330)
0.2 1.0 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.2 7.9 GO:0003954 NADH dehydrogenase activity(GO:0003954)
0.2 6.6 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.2 0.9 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.2 4.5 GO:0003951 NAD+ kinase activity(GO:0003951)
0.2 1.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.2 1.8 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.2 0.7 GO:0008147 structural constituent of bone(GO:0008147)
0.2 2.0 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.2 2.4 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.2 7.8 GO:0005109 frizzled binding(GO:0005109)
0.2 2.4 GO:0070403 NAD+ binding(GO:0070403)
0.1 2.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 1.4 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 1.7 GO:0050544 arachidonic acid binding(GO:0050544)
0.1 0.6 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 0.8 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 2.2 GO:0051787 misfolded protein binding(GO:0051787)
0.1 1.4 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.1 2.7 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 0.8 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.1 2.2 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.1 0.3 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.1 1.4 GO:0042923 neuropeptide binding(GO:0042923)
0.1 0.5 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
0.1 0.2 GO:0070991 medium-chain-acyl-CoA dehydrogenase activity(GO:0070991)
0.0 0.3 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.9 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.0 1.8 GO:0030332 cyclin binding(GO:0030332)
0.0 0.6 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 2.3 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 2.0 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.6 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.5 GO:0035174 histone serine kinase activity(GO:0035174)
0.0 3.5 GO:0005179 hormone activity(GO:0005179)
0.0 2.4 GO:0005518 collagen binding(GO:0005518)
0.0 0.4 GO:0015271 outward rectifier potassium channel activity(GO:0015271) potassium ion leak channel activity(GO:0022841)
0.0 0.5 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 2.9 GO:0019838 growth factor binding(GO:0019838)
0.0 0.6 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.0 0.7 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 1.8 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 3.1 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 2.2 GO:0004540 ribonuclease activity(GO:0004540)
0.0 1.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.4 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.7 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 1.5 GO:0070851 growth factor receptor binding(GO:0070851)
0.0 1.6 GO:0008201 heparin binding(GO:0008201)
0.0 1.1 GO:0035254 glutamate receptor binding(GO:0035254)
0.0 2.7 GO:0008236 serine-type peptidase activity(GO:0008236)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 6.6 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 1.3 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 2.8 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 5.6 PID ATF2 PATHWAY ATF-2 transcription factor network
0.1 7.8 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.1 3.6 PID SHP2 PATHWAY SHP2 signaling
0.1 3.4 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 2.6 PID BMP PATHWAY BMP receptor signaling
0.0 0.5 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 2.2 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.7 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 2.4 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 2.3 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 4.9 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.9 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 3.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.6 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 4.4 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.4 PID ATM PATHWAY ATM pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 17.0 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.4 5.0 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.3 2.7 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.2 2.8 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.2 2.4 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 3.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 1.7 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 1.3 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 6.1 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.1 1.8 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 1.4 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 6.0 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.1 2.0 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.1 0.4 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.1 3.6 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 2.0 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 1.3 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 8.9 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.5 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.4 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 1.7 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.6 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 1.1 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 2.2 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 2.8 REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE Genes involved in NGF signalling via TRKA from the plasma membrane
0.0 0.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation