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GSE58827: Dynamics of the Mouse Liver

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Results for Tbx5

Z-value: 1.37

Motif logo

Transcription factors associated with Tbx5

Gene Symbol Gene ID Gene Info
ENSMUSG00000018263.8 T-box 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tbx5mm10_v2_chr5_+_119834663_1198346630.289.8e-02Click!

Activity profile of Tbx5 motif

Sorted Z-values of Tbx5 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr14_+_80000292 10.98 ENSMUST00000088735.3
olfactomedin 4
chr10_+_75566257 10.95 ENSMUST00000129232.1
ENSMUST00000143792.1
gamma-glutamyltransferase 1
chr8_+_23035116 9.84 ENSMUST00000117296.1
ENSMUST00000141784.2
ankyrin 1, erythroid
chr4_-_134018829 9.18 ENSMUST00000051674.2
lin-28 homolog A (C. elegans)
chr11_-_87875524 8.30 ENSMUST00000049768.3
eosinophil peroxidase
chr7_-_142666816 8.04 ENSMUST00000105935.1
insulin-like growth factor 2
chr15_-_89425856 7.81 ENSMUST00000109313.2
carnitine palmitoyltransferase 1b, muscle
chr15_-_103255433 7.69 ENSMUST00000075192.6
nuclear factor, erythroid derived 2
chr1_-_132390301 6.98 ENSMUST00000132435.1
transmembrane and coiled-coil domains 2
chr3_-_20275659 6.92 ENSMUST00000011607.5
carboxypeptidase B1 (tissue)
chr14_-_56085214 6.83 ENSMUST00000015594.7
mast cell protease 8
chr8_-_105933832 6.67 ENSMUST00000034368.6
chymotrypsin-like
chr6_+_30639218 6.43 ENSMUST00000031806.9
carboxypeptidase A1, pancreatic
chr19_+_54045182 6.19 ENSMUST00000036700.5
adrenergic receptor, alpha 2a
chr3_-_100489324 5.77 ENSMUST00000061455.8
family with sequence similarity 46, member C
chr14_+_55765956 5.75 ENSMUST00000057569.3
leukotriene B4 receptor 1
chr4_+_115059507 5.62 ENSMUST00000162489.1
T cell acute lymphocytic leukemia 1
chr5_-_148399901 5.57 ENSMUST00000048116.8
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr11_-_69900930 5.48 ENSMUST00000018714.6
ENSMUST00000128046.1
RIKEN cDNA 2810408A11 gene
chr11_-_46312220 5.14 ENSMUST00000129474.1
ENSMUST00000093166.4
ENSMUST00000165599.2
cytoplasmic FMR1 interacting protein 2
chr15_-_89425795 5.13 ENSMUST00000168376.1
carnitine palmitoyltransferase 1b, muscle
chr11_-_69900949 5.10 ENSMUST00000102580.3
RIKEN cDNA 2810408A11 gene
chr11_-_116076986 4.94 ENSMUST00000153408.1
unc-13 homolog D (C. elegans)
chr2_+_103970115 4.89 ENSMUST00000111143.1
ENSMUST00000138815.1
LIM domain only 2
chr1_-_193035651 4.86 ENSMUST00000016344.7
synaptotagmin XIV
chr1_+_135133272 4.69 ENSMUST00000167080.1
protein tyrosine phosphatase, non-receptor type 7
chr14_-_51057242 4.55 ENSMUST00000089798.2
ribonuclease, RNase A family, 12 (non-active)
chr9_-_95845215 4.52 ENSMUST00000093800.2
plastin 1 (I-isoform)
chr7_+_113513854 4.43 ENSMUST00000067929.8
ENSMUST00000129087.1
ENSMUST00000164745.1
ENSMUST00000136158.1
fatty acyl CoA reductase 1
chr4_+_154869585 4.28 ENSMUST00000079269.7
ENSMUST00000163732.1
ENSMUST00000080559.6
membrane metallo-endopeptidase-like 1
chr2_+_103970221 4.27 ENSMUST00000111140.2
ENSMUST00000111139.2
LIM domain only 2
chr3_+_108383829 4.18 ENSMUST00000090561.3
ENSMUST00000102629.1
ENSMUST00000128089.1
proline/serine-rich coiled-coil 1
chrX_+_100625737 4.10 ENSMUST00000048962.3
kinesin family member 4
chr11_+_72961163 4.08 ENSMUST00000108486.1
ENSMUST00000108484.1
ENSMUST00000021142.7
ENSMUST00000108485.2
ENSMUST00000163326.1
ATPase, Ca++ transporting, ubiquitous
chr7_+_28982832 3.92 ENSMUST00000085835.6
mitogen-activated protein kinase kinase kinase kinase 1
chrX_-_49797700 3.89 ENSMUST00000033442.7
ENSMUST00000114891.1
immunoglobulin superfamily, member 1
chr11_+_69095217 3.77 ENSMUST00000101004.2
period circadian clock 1
chr1_+_91366412 3.70 ENSMUST00000086861.5
family with sequence similarity 132, member B
chr2_-_181691771 3.62 ENSMUST00000108778.1
ENSMUST00000165416.1
regulator of G-protein signaling 19
chr2_-_32387760 3.61 ENSMUST00000050785.8
lipocalin 2
chr7_+_113513829 3.57 ENSMUST00000033018.8
fatty acyl CoA reductase 1
chr7_+_81858993 3.53 ENSMUST00000041890.1
transmembrane 6 superfamily member 1
chr7_-_45239108 3.52 ENSMUST00000033063.6
CD37 antigen
chr11_+_53519725 3.44 ENSMUST00000108987.1
ENSMUST00000121334.1
ENSMUST00000117061.1
septin 8
chr7_-_141117772 3.32 ENSMUST00000067836.7
anoctamin 9
chr6_-_49214954 3.31 ENSMUST00000031838.7
insulin-like growth factor 2 mRNA binding protein 3
chr8_-_121907678 3.31 ENSMUST00000045557.9
solute carrier family 7 (cationic amino acid transporter, y+ system), member 5
chr5_-_137741601 3.22 ENSMUST00000119498.1
ENSMUST00000061789.7
neuronal tyrosine-phosphorylated phosphoinositide 3-kinase adaptor 1
chr8_-_105637403 3.20 ENSMUST00000182046.1
predicted gene 5914
chrX_-_36989656 3.15 ENSMUST00000060474.7
ENSMUST00000053456.4
ENSMUST00000115239.3
septin 6
chr7_-_45239041 3.12 ENSMUST00000131290.1
CD37 antigen
chr15_+_79347534 2.96 ENSMUST00000096350.3
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)
chr9_+_108991902 2.95 ENSMUST00000147989.1
ENSMUST00000051873.8
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
chr18_-_54990124 2.93 ENSMUST00000064763.5
zinc finger protein 608
chr3_+_123446913 2.86 ENSMUST00000029603.8
protease, serine, 12 neurotrypsin (motopsin)
chr7_-_45238794 2.84 ENSMUST00000098461.1
ENSMUST00000107797.1
CD37 antigen
chr14_+_65266701 2.81 ENSMUST00000169656.1
F-box protein 16
chr8_-_85119637 2.80 ENSMUST00000098550.3
zinc finger protein 791
chrX_+_134295225 2.80 ENSMUST00000037687.7
transmembrane protein 35
chr7_-_104950441 2.70 ENSMUST00000179862.1
predicted pseudogene 5900
chr17_-_25952565 2.63 ENSMUST00000162431.1
RIKEN cDNA A930017K11 gene
chr3_+_103102604 2.62 ENSMUST00000173206.1
DENN/MADD domain containing 2C
chr9_+_86743641 2.61 ENSMUST00000179574.1
protease, serine, 35
chr5_-_137741102 2.58 ENSMUST00000149512.1
neuronal tyrosine-phosphorylated phosphoinositide 3-kinase adaptor 1
chr9_+_75232013 2.58 ENSMUST00000036555.6
myosin VC
chr12_-_113422730 2.57 ENSMUST00000177715.1
ENSMUST00000103426.1
immunoglobulin heavy constant mu
chr19_-_46327121 2.54 ENSMUST00000041391.4
ENSMUST00000096029.5
pleckstrin and Sec7 domain containing
chrX_+_159840463 2.52 ENSMUST00000112451.1
ENSMUST00000112453.2
SH3-domain kinase binding protein 1
chr5_+_143622466 2.51 ENSMUST00000177196.1
cytohesin 3
chr3_+_130180882 2.46 ENSMUST00000106353.1
ENSMUST00000080335.4
collagen, type XXV, alpha 1
chr15_-_83033294 2.35 ENSMUST00000100377.4
Nfat activating molecule with ITAM motif 1
chr4_+_103619580 2.34 ENSMUST00000106827.1
disabled 1
chr17_+_47505211 2.32 ENSMUST00000182935.1
ENSMUST00000182506.1
cyclin D3
chr9_+_73044833 2.30 ENSMUST00000184146.1
ENSMUST00000034722.4
RAB27A, member RAS oncogene family
chr8_+_120537423 2.30 ENSMUST00000118136.1
genetic suppressor element 1
chr11_-_8973266 2.26 ENSMUST00000154153.1
polycystic kidney disease 1 like 1
chr7_-_141443989 2.25 ENSMUST00000026580.5
leucine-rich and death domain containing
chr9_+_86743616 2.25 ENSMUST00000036426.6
protease, serine, 35
chr5_-_24329556 2.22 ENSMUST00000115098.2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr19_+_38931008 2.19 ENSMUST00000145051.1
helicase, lymphoid specific
chr17_+_47505043 2.16 ENSMUST00000182129.1
ENSMUST00000171031.1
cyclin D3
chr4_-_43045686 2.15 ENSMUST00000107956.1
ENSMUST00000107957.1
family with sequence similarity 214, member B
chr11_+_96929367 2.12 ENSMUST00000062172.5
proline rich 15-like
chrX_-_51205990 2.12 ENSMUST00000114876.2
muscleblind-like 3 (Drosophila)
chr11_-_106301801 2.11 ENSMUST00000103071.3
growth hormone
chr10_+_60346851 2.09 ENSMUST00000020301.7
ENSMUST00000105460.1
ENSMUST00000170507.1
RIKEN cDNA 4632428N05 gene
chr19_+_38097065 2.08 ENSMUST00000067098.6
free fatty acid receptor 4
chr17_+_47505149 2.07 ENSMUST00000183177.1
ENSMUST00000182848.1
cyclin D3
chr17_+_47505117 2.06 ENSMUST00000183044.1
ENSMUST00000037333.10
cyclin D3
chr10_-_91082653 2.06 ENSMUST00000159110.1
apoptotic peptidase activating factor 1
chr5_+_143622440 2.06 ENSMUST00000116456.3
cytohesin 3
chr4_+_58943575 2.00 ENSMUST00000107554.1
zinc finger with KRAB and SCAN domains 16
chr3_-_126998408 2.00 ENSMUST00000182764.1
ENSMUST00000044443.8
ankyrin 2, brain
chr7_-_4546567 2.00 ENSMUST00000065957.5
synaptotagmin V
chr8_-_68121527 1.99 ENSMUST00000178529.1
predicted gene, 21807
chr7_+_141131268 1.99 ENSMUST00000026568.8
phosphatidylserine synthase 2
chr3_-_65529355 1.97 ENSMUST00000099076.3
RIKEN cDNA 4931440P22 gene
chr15_-_75888754 1.97 ENSMUST00000184858.1
maestro heat-like repeat family member 6
chr7_+_43437073 1.96 ENSMUST00000070518.2
natural killer cell group 7 sequence
chr19_-_10304867 1.93 ENSMUST00000039327.4
diacylglycerol lipase, alpha
chr2_-_54085542 1.93 ENSMUST00000100089.2
reprimo, TP53 dependent G2 arrest mediator candidate
chr17_+_47726834 1.92 ENSMUST00000024782.5
ENSMUST00000144955.1
progastricsin (pepsinogen C)
chrX_-_51205773 1.90 ENSMUST00000114875.1
muscleblind-like 3 (Drosophila)
chr15_-_99457712 1.90 ENSMUST00000161948.1
NCK-associated protein 5-like
chr1_+_66364623 1.88 ENSMUST00000077355.5
ENSMUST00000114012.1
microtubule-associated protein 2
chr11_-_69900886 1.80 ENSMUST00000108621.2
ENSMUST00000100969.2
RIKEN cDNA 2810408A11 gene
chr10_-_91082704 1.80 ENSMUST00000162618.1
ENSMUST00000020157.6
ENSMUST00000160788.1
apoptotic peptidase activating factor 1
chr4_-_117883428 1.80 ENSMUST00000030266.5
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
chr16_+_17276291 1.79 ENSMUST00000164950.1
ENSMUST00000159242.1
transmembrane protein 191C
chr8_+_83389846 1.76 ENSMUST00000002259.6
calmegin
chr6_-_52158292 1.76 ENSMUST00000000964.5
ENSMUST00000120363.1
homeobox A1
chrX_+_100729917 1.74 ENSMUST00000019503.7
glycerophosphodiester phosphodiesterase domain containing 2
chr7_-_102100227 1.74 ENSMUST00000106937.1
ADP-ribosyltransferase 5
chr9_-_35558522 1.74 ENSMUST00000034612.5
DEAD (Asp-Glu-Ala-Asp) box polypeptide 25
chr1_+_87620306 1.72 ENSMUST00000169754.1
inositol polyphosphate-5-phosphatase D
chrX_-_7740206 1.72 ENSMUST00000128289.1
coiled-coil domain containing 120
chr8_+_83389878 1.69 ENSMUST00000109831.2
calmegin
chr15_-_27681498 1.69 ENSMUST00000100739.3
family with sequence similarity 105, member A
chr16_+_17276337 1.68 ENSMUST00000159065.1
ENSMUST00000159494.1
ENSMUST00000159811.1
transmembrane protein 191C
chr11_+_69965396 1.68 ENSMUST00000018713.6
claudin 7
chr4_+_132564051 1.68 ENSMUST00000070690.7
platelet-activating factor receptor
chr19_+_38930909 1.67 ENSMUST00000025965.5
helicase, lymphoid specific
chr8_-_105637350 1.67 ENSMUST00000182863.1
predicted gene 5914
chr3_-_127225917 1.64 ENSMUST00000182064.1
ENSMUST00000182662.1
ankyrin 2, brain
chr9_+_107580746 1.63 ENSMUST00000148440.1
hyaluronoglucosaminidase 3
chr11_+_98383811 1.63 ENSMUST00000008021.2
titin-cap
chr2_-_44927161 1.59 ENSMUST00000130991.1
glycosyltransferase-like domain containing 1
chr3_-_127225847 1.58 ENSMUST00000182726.1
ENSMUST00000182779.1
ankyrin 2, brain
chr2_+_121358591 1.58 ENSMUST00000000317.6
ENSMUST00000129130.1
creatine kinase, mitochondrial 1, ubiquitous
chrX_+_135885851 1.56 ENSMUST00000180025.1
ENSMUST00000068755.7
ENSMUST00000148374.1
basic helix-loop-helix domain containing, class B9
chr6_+_48718602 1.52 ENSMUST00000127537.1
ENSMUST00000155017.2
GTPase IMAP family member 1
chr5_-_22344690 1.52 ENSMUST00000062372.7
ENSMUST00000161356.1
reelin
chr15_-_99457742 1.52 ENSMUST00000023747.7
NCK-associated protein 5-like
chr11_+_78188422 1.51 ENSMUST00000002128.7
ENSMUST00000150941.1
RAB34, member of RAS oncogene family
chr2_-_44927206 1.51 ENSMUST00000100127.2
glycosyltransferase-like domain containing 1
chr7_-_45824750 1.49 ENSMUST00000071937.5
potassium inwardly-rectifying channel, subfamily J, member 14
chrX_-_147554050 1.48 ENSMUST00000112819.2
ENSMUST00000136789.1
leucine-rich repeats and calponin homology (CH) domain containing 2
chr6_+_35252692 1.47 ENSMUST00000130875.1
RIKEN cDNA 1810058I24 gene
chr11_+_96929260 1.46 ENSMUST00000054311.5
ENSMUST00000107636.3
proline rich 15-like
chr1_+_135836380 1.45 ENSMUST00000178204.1
troponin T2, cardiac
chr2_+_121357714 1.44 ENSMUST00000125812.1
ENSMUST00000078222.2
ENSMUST00000125221.1
ENSMUST00000150271.1
creatine kinase, mitochondrial 1, ubiquitous
chr11_-_6606053 1.44 ENSMUST00000045713.3
NAC alpha domain containing
chr6_+_35252654 1.43 ENSMUST00000152147.1
RIKEN cDNA 1810058I24 gene
chr7_+_123214776 1.42 ENSMUST00000131933.1
solute carrier family 5 (sodium/glucose cotransporter), member 11
chr17_+_48264270 1.42 ENSMUST00000059873.7
ENSMUST00000154335.1
ENSMUST00000136272.1
ENSMUST00000125426.1
ENSMUST00000153420.1
triggering receptor expressed on myeloid cells-like 4
chr11_+_54304180 1.41 ENSMUST00000108904.3
ENSMUST00000108905.3
acyl-CoA synthetase long-chain family member 6
chr6_-_56901870 1.39 ENSMUST00000101367.2
5'-nucleotidase, cytosolic III
chr6_+_35252724 1.37 ENSMUST00000136110.1
RIKEN cDNA 1810058I24 gene
chr11_+_54304005 1.37 ENSMUST00000000145.5
ENSMUST00000138515.1
acyl-CoA synthetase long-chain family member 6
chr6_+_17307040 1.34 ENSMUST00000123439.1
caveolin 1, caveolae protein
chr6_+_115134899 1.34 ENSMUST00000009538.5
ENSMUST00000169345.1
synapsin II
chr6_-_28831747 1.33 ENSMUST00000062304.5
leucine rich repeat containing 4
chr4_+_119814495 1.32 ENSMUST00000106307.2
human immunodeficiency virus type I enhancer binding protein 3
chr6_+_41684414 1.31 ENSMUST00000031900.5
RIKEN cDNA 1700034O15 gene
chr17_+_5975740 1.31 ENSMUST00000115790.1
synaptojanin 2
chr17_+_47505073 1.30 ENSMUST00000183210.1
cyclin D3
chr8_-_80739497 1.30 ENSMUST00000043359.8
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
chr11_+_96323253 1.30 ENSMUST00000093944.3
homeobox B3
chrX_-_136085206 1.29 ENSMUST00000138878.1
ENSMUST00000080929.6
nuclear RNA export factor 3
chrX_+_100730178 1.29 ENSMUST00000113744.1
glycerophosphodiester phosphodiesterase domain containing 2
chr7_-_115824699 1.26 ENSMUST00000169129.1
SRY-box containing gene 6
chr12_+_51348370 1.26 ENSMUST00000121521.1
G2/M-phase specific E3 ubiquitin ligase
chr11_-_70220776 1.24 ENSMUST00000141290.1
solute carrier family 16 (monocarboxylic acid transporters), member 13
chr9_-_59146210 1.23 ENSMUST00000085631.2
predicted gene 7589
chr17_+_21383725 1.23 ENSMUST00000056107.4
ENSMUST00000162659.1
zinc finger protein 677
chr7_+_25267669 1.23 ENSMUST00000169266.1
capicua homolog (Drosophila)
chr15_+_103453782 1.21 ENSMUST00000047405.7
NCK associated protein 1 like
chr12_-_27342696 1.19 ENSMUST00000079063.5
SRY-box containing gene 11
chr2_+_24186469 1.19 ENSMUST00000057567.2
interleukin 1 family, member 9
chr7_-_35396708 1.19 ENSMUST00000154597.1
ENSMUST00000032704.5
RIKEN cDNA C230052I12 gene
chr7_-_140082246 1.16 ENSMUST00000166758.2
calcyon neuron-specific vesicular protein
chr6_+_4504814 1.16 ENSMUST00000141483.1
collagen, type I, alpha 2
chr17_+_32036098 1.16 ENSMUST00000081339.6
ribosomal RNA processing 1 homolog B (S. cerevisiae)
chr11_-_120598346 1.15 ENSMUST00000026125.2
Aly/REF export factor
chr15_-_63997969 1.15 ENSMUST00000164532.1
family with sequence similarity 49, member B
chr1_-_178337774 1.15 ENSMUST00000037748.7
heterogeneous nuclear ribonucleoprotein U
chr11_+_20647149 1.14 ENSMUST00000109585.1
SERTA domain containing 2
chr5_-_143292356 1.14 ENSMUST00000180336.1
zinc finger protein 853
chr12_+_51348019 1.14 ENSMUST00000054308.6
G2/M-phase specific E3 ubiquitin ligase
chrX_+_42151002 1.12 ENSMUST00000123245.1
stromal antigen 2
chr6_+_54681687 1.12 ENSMUST00000046276.6
RIKEN cDNA 2410066E13 gene
chr11_-_70220794 1.12 ENSMUST00000159867.1
solute carrier family 16 (monocarboxylic acid transporters), member 13
chr1_-_167285110 1.12 ENSMUST00000027839.8
uridine-cytidine kinase 2
chr8_+_125669818 1.09 ENSMUST00000053078.3
microtubule-associated protein 10
chr7_-_44748617 1.09 ENSMUST00000060270.6
zinc finger protein 473
chr9_-_96437434 1.09 ENSMUST00000070500.2
cDNA sequence BC043934
chr13_+_118714678 1.06 ENSMUST00000022246.8
fibroblast growth factor 10
chr1_+_63273261 1.06 ENSMUST00000114132.1
ENSMUST00000126932.1
zinc finger, DBF-type containing 2
chr3_+_126597299 1.06 ENSMUST00000106400.2
ENSMUST00000106401.1
calcium/calmodulin-dependent protein kinase II, delta
chr10_-_14544972 1.03 ENSMUST00000041168.4
G protein-coupled receptor 126
chr11_-_70220969 1.03 ENSMUST00000060010.2
solute carrier family 16 (monocarboxylic acid transporters), member 13
chr3_-_95306794 1.03 ENSMUST00000107183.1
ENSMUST00000164406.1
ENSMUST00000123365.1
annexin A9
chr5_+_113490447 1.03 ENSMUST00000094452.3
WSC domain containing 2
chr18_+_82914632 0.99 ENSMUST00000071233.6
zinc finger protein 516
chr6_-_28830345 0.99 ENSMUST00000171353.1
leucine rich repeat containing 4
chr1_+_93373874 0.98 ENSMUST00000058682.4
anoctamin 7
chr5_+_17574726 0.98 ENSMUST00000169603.1
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr18_+_36793918 0.98 ENSMUST00000001419.8
zinc finger, matrin type 2
chr19_-_6925367 0.96 ENSMUST00000057716.4
testis expressed 40
chr7_-_113369326 0.94 ENSMUST00000047091.7
ENSMUST00000119278.1
BTB (POZ) domain containing 10

Network of associatons between targets according to the STRING database.

First level regulatory network of Tbx5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 8.3 GO:0002215 defense response to nematode(GO:0002215)
1.9 5.6 GO:0060217 hemangioblast cell differentiation(GO:0060217)
1.4 10.9 GO:1901748 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
1.3 8.0 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
1.1 4.5 GO:1902896 terminal web assembly(GO:1902896)
1.1 10.1 GO:0010587 miRNA catabolic process(GO:0010587)
1.1 3.3 GO:2001226 negative regulation of chloride transport(GO:2001226)
1.0 6.2 GO:0035625 receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
1.0 8.0 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
1.0 3.9 GO:0097477 lateral motor column neuron migration(GO:0097477)
0.9 9.5 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
0.9 2.6 GO:0002343 peripheral B cell selection(GO:0002343) B cell affinity maturation(GO:0002344)
0.8 3.8 GO:0097167 circadian regulation of translation(GO:0097167)
0.8 2.3 GO:0003127 detection of nodal flow(GO:0003127) detection of endogenous stimulus(GO:0009726)
0.7 8.4 GO:0034242 negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.6 9.2 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.6 1.8 GO:0021570 rhombomere 4 development(GO:0021570)
0.6 5.2 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.6 1.1 GO:0035709 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.6 1.1 GO:2000373 regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
0.6 1.7 GO:1904306 positive regulation of gastro-intestinal system smooth muscle contraction(GO:1904306)
0.6 2.2 GO:1902303 negative regulation of potassium ion export(GO:1902303)
0.6 3.9 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.5 4.9 GO:0002432 granuloma formation(GO:0002432)
0.5 5.2 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.5 3.6 GO:1901678 iron coordination entity transport(GO:1901678)
0.5 4.1 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.5 2.0 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.5 2.5 GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.5 1.9 GO:0046340 diacylglycerol catabolic process(GO:0046340) retrograde trans-synaptic signaling(GO:0098917)
0.5 3.9 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.5 1.4 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.5 2.8 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
0.5 2.3 GO:0097278 complement-dependent cytotoxicity(GO:0097278)
0.5 1.8 GO:0061386 closure of optic fissure(GO:0061386)
0.4 9.9 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.4 1.7 GO:0045659 negative regulation of neutrophil differentiation(GO:0045659)
0.4 2.1 GO:1905169 protein localization to phagocytic vesicle(GO:1905161) regulation of protein localization to phagocytic vesicle(GO:1905169) positive regulation of protein localization to phagocytic vesicle(GO:1905171)
0.4 1.9 GO:0002760 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.4 1.1 GO:0006222 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.4 2.2 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.4 1.1 GO:0070350 bronchiole development(GO:0060435) secretion by lung epithelial cell involved in lung growth(GO:0061033) white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350) positive regulation of hair follicle cell proliferation(GO:0071338)
0.4 2.5 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.3 5.6 GO:0015809 arginine transport(GO:0015809)
0.3 2.9 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.3 0.3 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.3 3.0 GO:0090527 actin filament reorganization(GO:0090527)
0.3 1.2 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376) actin polymerization-dependent cell motility(GO:0070358)
0.3 2.3 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.3 1.6 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.3 1.6 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.3 11.1 GO:0048821 erythrocyte development(GO:0048821)
0.3 0.5 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.2 1.0 GO:0061589 calcium activated phosphatidylserine scrambling(GO:0061589)
0.2 1.0 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.2 0.7 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.2 1.4 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.2 0.7 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.2 11.0 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.2 6.2 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.2 0.6 GO:0034184 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.2 2.3 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.2 1.3 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.2 0.7 GO:0035522 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.2 0.5 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476) nuclear polyadenylation-dependent mRNA catabolic process(GO:0071042) polyadenylation-dependent mRNA catabolic process(GO:0071047)
0.2 0.2 GO:0001575 globoside metabolic process(GO:0001575)
0.2 0.7 GO:1902514 regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.2 1.3 GO:0016584 nucleosome positioning(GO:0016584)
0.2 13.2 GO:0015909 long-chain fatty acid transport(GO:0015909)
0.2 0.5 GO:0019046 release from viral latency(GO:0019046)
0.2 0.5 GO:0002309 T cell proliferation involved in immune response(GO:0002309) regulation of T-helper 17 cell lineage commitment(GO:2000328)
0.2 0.9 GO:0097527 necroptotic signaling pathway(GO:0097527)
0.2 0.3 GO:1902606 regulation of large conductance calcium-activated potassium channel activity(GO:1902606) positive regulation of large conductance calcium-activated potassium channel activity(GO:1902608)
0.1 2.1 GO:0090031 positive regulation of steroid hormone biosynthetic process(GO:0090031)
0.1 2.6 GO:0032252 secretory granule localization(GO:0032252)
0.1 0.4 GO:1902277 negative regulation of pancreatic amylase secretion(GO:1902277)
0.1 0.4 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.1 1.2 GO:0043589 skin morphogenesis(GO:0043589)
0.1 0.9 GO:0036005 response to macrophage colony-stimulating factor(GO:0036005) cellular response to macrophage colony-stimulating factor stimulus(GO:0036006)
0.1 0.3 GO:0042823 pyridoxal phosphate biosynthetic process(GO:0042823)
0.1 1.1 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.1 0.6 GO:0048496 maintenance of organ identity(GO:0048496)
0.1 0.4 GO:0003349 epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
0.1 1.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 4.2 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.1 0.7 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 3.7 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.1 6.4 GO:0007019 microtubule depolymerization(GO:0007019)
0.1 1.4 GO:1904659 glucose transmembrane transport(GO:1904659)
0.1 0.3 GO:1900248 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.1 1.4 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 0.4 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.1 0.3 GO:0021852 pyramidal neuron migration(GO:0021852)
0.1 0.5 GO:2000224 regulation of testosterone biosynthetic process(GO:2000224)
0.1 0.5 GO:2001205 negative regulation of osteoclast development(GO:2001205)
0.1 0.6 GO:0061577 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577)
0.1 5.1 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.1 4.7 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.1 0.7 GO:0071816 maintenance of unfolded protein(GO:0036506) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.1 1.7 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.1 0.3 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.1 1.8 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 0.6 GO:0048539 bone marrow development(GO:0048539)
0.1 1.6 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.1 3.5 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.1 0.4 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.1 1.2 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.1 5.2 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.1 0.2 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979)
0.1 1.0 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 0.3 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.1 2.4 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.1 0.2 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 1.2 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 0.8 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.1 0.6 GO:0099628 receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628) regulation of grooming behavior(GO:2000821)
0.0 0.6 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 4.5 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 1.6 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 1.4 GO:0010107 potassium ion import(GO:0010107)
0.0 0.6 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 2.1 GO:0050710 negative regulation of cytokine secretion(GO:0050710)
0.0 5.3 GO:0014065 phosphatidylinositol 3-kinase signaling(GO:0014065)
0.0 4.2 GO:0051028 mRNA transport(GO:0051028)
0.0 1.8 GO:0021680 cerebellar Purkinje cell layer development(GO:0021680)
0.0 0.9 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.0 0.8 GO:0042711 maternal behavior(GO:0042711)
0.0 4.9 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.7 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 4.1 GO:0006906 vesicle fusion(GO:0006906)
0.0 0.3 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.0 0.6 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.0 0.4 GO:2000637 positive regulation of gene silencing by miRNA(GO:2000637)
0.0 1.0 GO:0009409 response to cold(GO:0009409)
0.0 0.9 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.2 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.1 GO:0060214 endocardium formation(GO:0060214)
0.0 0.5 GO:1901099 negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 1.2 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 1.9 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.1 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.3 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.3 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 1.2 GO:0007269 neurotransmitter secretion(GO:0007269) signal release from synapse(GO:0099643)
0.0 0.4 GO:0001919 regulation of receptor recycling(GO:0001919)
0.0 0.0 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 5.6 GO:0033193 Lsd1/2 complex(GO:0033193)
1.0 3.1 GO:0005940 septin ring(GO:0005940)
1.0 3.9 GO:0043293 apoptosome(GO:0043293)
0.9 12.4 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.7 11.0 GO:0042581 specific granule(GO:0042581)
0.7 7.2 GO:0033093 Weibel-Palade body(GO:0033093)
0.6 4.5 GO:1990357 terminal web(GO:1990357)
0.6 2.2 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.4 1.3 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.4 9.8 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.4 2.0 GO:1990769 proximal neuron projection(GO:1990769)
0.4 1.2 GO:0005584 collagen type I trimer(GO:0005584)
0.4 2.6 GO:0019815 B cell receptor complex(GO:0019815)
0.3 8.0 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.2 1.4 GO:1990584 cardiac Troponin complex(GO:1990584)
0.2 3.2 GO:0043083 synaptic cleft(GO:0043083)
0.2 1.9 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.2 0.6 GO:0035061 interchromatin granule(GO:0035061)
0.2 1.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.2 2.5 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.2 9.7 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 5.6 GO:0043034 costamere(GO:0043034)
0.1 1.8 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.1 0.6 GO:1990696 USH2 complex(GO:1990696)
0.1 1.5 GO:0005677 chromatin silencing complex(GO:0005677)
0.1 0.7 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.1 1.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 7.2 GO:0001772 immunological synapse(GO:0001772)
0.1 0.3 GO:0032127 dense core granule membrane(GO:0032127)
0.1 3.8 GO:0005721 pericentric heterochromatin(GO:0005721)
0.1 0.7 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1 1.2 GO:0031209 SCAR complex(GO:0031209)
0.1 9.8 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 1.9 GO:0043196 varicosity(GO:0043196)
0.1 0.8 GO:0043596 nuclear replication fork(GO:0043596)
0.1 1.2 GO:0043194 axon initial segment(GO:0043194)
0.1 1.7 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 4.1 GO:0045171 intercellular bridge(GO:0045171)
0.1 0.7 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 1.1 GO:0033391 chromatoid body(GO:0033391)
0.1 0.6 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 0.7 GO:0042629 mast cell granule(GO:0042629)
0.1 1.1 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 1.1 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 11.0 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 2.8 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.5 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.7 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.6 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 6.7 GO:0030139 endocytic vesicle(GO:0030139)
0.0 2.1 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.2 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.6 GO:0036038 MKS complex(GO:0036038)
0.0 0.6 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 1.0 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.0 6.6 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 1.1 GO:0015030 Cajal body(GO:0015030)
0.0 2.3 GO:0030863 cortical cytoskeleton(GO:0030863)
0.0 1.3 GO:0031201 SNARE complex(GO:0031201)
0.0 0.8 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 1.7 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 4.6 GO:0001726 ruffle(GO:0001726)
0.0 0.6 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.3 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 7.4 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 2.6 GO:0030027 lamellipodium(GO:0030027)
0.0 0.4 GO:0035371 microtubule plus-end(GO:0035371)
0.0 5.8 GO:0030141 secretory granule(GO:0030141)
0.0 3.0 GO:0044455 mitochondrial membrane part(GO:0044455)
0.0 0.1 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.6 GO:0005801 cis-Golgi network(GO:0005801)
0.0 1.0 GO:0005814 centriole(GO:0005814)
0.0 20.4 GO:0005615 extracellular space(GO:0005615)
0.0 0.5 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.4 GO:0090544 BAF-type complex(GO:0090544)
0.0 1.3 GO:0043197 dendritic spine(GO:0043197)
0.0 0.7 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.3 GO:0097546 ciliary base(GO:0097546)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 12.9 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
1.6 8.0 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
1.5 6.2 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
1.4 5.7 GO:0004974 leukotriene receptor activity(GO:0004974)
1.0 9.8 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.9 10.9 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.8 9.5 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.7 5.6 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.6 2.4 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.6 1.8 GO:0004461 lactose synthase activity(GO:0004461)
0.5 1.6 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.5 3.0 GO:0004111 creatine kinase activity(GO:0004111)
0.5 2.5 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.4 3.9 GO:0034711 inhibin binding(GO:0034711)
0.4 13.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.4 1.1 GO:0023025 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.4 2.2 GO:0000155 phosphorelay sensor kinase activity(GO:0000155) voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.3 3.0 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.3 1.7 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.3 2.9 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.3 1.6 GO:0051373 FATZ binding(GO:0051373)
0.3 16.8 GO:0070888 E-box binding(GO:0070888)
0.3 1.7 GO:0051425 PTB domain binding(GO:0051425)
0.3 1.1 GO:0034046 poly(G) binding(GO:0034046)
0.3 2.1 GO:0005131 growth hormone receptor binding(GO:0005131)
0.3 1.5 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.2 2.0 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.2 0.7 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.2 8.0 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.2 3.2 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.2 2.2 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.2 1.9 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.2 4.4 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.2 2.9 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.2 1.1 GO:0004849 uridine kinase activity(GO:0004849)
0.2 2.1 GO:0008527 taste receptor activity(GO:0008527)
0.2 1.4 GO:0031013 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.2 9.9 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.2 0.9 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.2 6.2 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.2 8.6 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.2 0.7 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.2 7.7 GO:0050699 WW domain binding(GO:0050699)
0.2 0.5 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.2 3.5 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.4 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 1.2 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 2.8 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 1.8 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.1 3.3 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 0.9 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.7 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 4.1 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 8.4 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 1.8 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 1.4 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 1.9 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.8 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 0.5 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.1 6.2 GO:0004601 peroxidase activity(GO:0004601)
0.1 2.5 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 3.5 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 0.3 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.1 2.1 GO:0017160 Ral GTPase binding(GO:0017160)
0.1 0.4 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 2.3 GO:0031489 myosin V binding(GO:0031489)
0.1 0.6 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 0.6 GO:0031812 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.1 1.9 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.1 1.4 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 4.3 GO:0030507 spectrin binding(GO:0030507)
0.1 0.4 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467) very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 0.5 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 3.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 0.3 GO:0004966 galanin receptor activity(GO:0004966)
0.1 0.5 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.1 3.0 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.1 0.2 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 1.2 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.1 0.8 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 2.5 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 2.3 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.3 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.0 0.9 GO:0005123 death receptor binding(GO:0005123)
0.0 0.1 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.0 0.8 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.8 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 6.9 GO:0004386 helicase activity(GO:0004386)
0.0 0.6 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.5 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.6 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 1.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.3 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 6.4 GO:0008236 serine-type peptidase activity(GO:0008236)
0.0 1.0 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 4.2 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.4 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 3.9 GO:0004519 endonuclease activity(GO:0004519)
0.0 0.3 GO:0010181 FMN binding(GO:0010181)
0.0 3.4 GO:0015293 symporter activity(GO:0015293)
0.0 3.1 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 2.5 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 1.2 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 1.3 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 1.2 GO:0030295 protein kinase activator activity(GO:0030295)
0.0 0.6 GO:0017022 myosin binding(GO:0017022)
0.0 0.3 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.8 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.6 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 1.5 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 1.1 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.4 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.1 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.7 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.3 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.7 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.0 1.1 GO:0004222 metalloendopeptidase activity(GO:0004222)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.9 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.2 4.7 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.2 3.8 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.2 3.9 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.2 8.8 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 2.5 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.1 6.2 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.1 8.2 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 3.5 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 2.5 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 4.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 3.4 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 2.5 PID IFNG PATHWAY IFN-gamma pathway
0.1 2.5 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 3.2 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.4 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 1.9 PID LKB1 PATHWAY LKB1 signaling events
0.0 1.9 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.7 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.6 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.7 PID RHOA PATHWAY RhoA signaling pathway
0.0 1.1 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.9 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 10.8 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.4 8.0 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.3 10.9 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.2 8.9 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 9.9 REACTOME G1 PHASE Genes involved in G1 Phase
0.2 9.3 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.2 6.2 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 2.0 REACTOME REGULATION OF INSULIN SECRETION Genes involved in Regulation of Insulin Secretion
0.1 0.6 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1 1.3 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.1 2.5 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 3.4 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 2.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 3.9 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.1 2.3 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.1 2.1 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 1.3 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 0.7 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 1.4 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.1 1.8 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 1.1 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.1 2.3 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.1 3.8 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 2.9 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 2.5 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.1 3.1 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.3 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 0.5 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 7.1 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 2.3 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.7 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.5 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.7 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 1.8 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.8 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 2.3 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.9 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.0 0.7 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 1.1 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 1.3 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.2 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.9 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 1.7 REACTOME MRNA SPLICING Genes involved in mRNA Splicing