Motif ID: Tbx5

Z-value: 1.370


Transcription factors associated with Tbx5:

Gene SymbolEntrez IDGene Name
Tbx5 ENSMUSG00000018263.8 Tbx5

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tbx5mm10_v2_chr5_+_119834663_1198346630.289.8e-02Click!


Activity profile for motif Tbx5.

activity profile for motif Tbx5


Sorted Z-values histogram for motif Tbx5

Sorted Z-values for motif Tbx5



Network of associatons between targets according to the STRING database.



First level regulatory network of Tbx5

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_+_80000292 10.980 ENSMUST00000088735.3
Olfm4
olfactomedin 4
chr10_+_75566257 10.950 ENSMUST00000129232.1
ENSMUST00000143792.1
Ggt1

gamma-glutamyltransferase 1

chr8_+_23035116 9.841 ENSMUST00000117296.1
ENSMUST00000141784.2
Ank1

ankyrin 1, erythroid

chr4_-_134018829 9.179 ENSMUST00000051674.2
Lin28a
lin-28 homolog A (C. elegans)
chr11_-_87875524 8.299 ENSMUST00000049768.3
Epx
eosinophil peroxidase
chr7_-_142666816 8.045 ENSMUST00000105935.1
Igf2
insulin-like growth factor 2
chr15_-_89425856 7.808 ENSMUST00000109313.2
Cpt1b
carnitine palmitoyltransferase 1b, muscle
chr15_-_103255433 7.692 ENSMUST00000075192.6
Nfe2
nuclear factor, erythroid derived 2
chr1_-_132390301 6.984 ENSMUST00000132435.1
Tmcc2
transmembrane and coiled-coil domains 2
chr3_-_20275659 6.918 ENSMUST00000011607.5
Cpb1
carboxypeptidase B1 (tissue)
chr14_-_56085214 6.834 ENSMUST00000015594.7
Mcpt8
mast cell protease 8
chr8_-_105933832 6.669 ENSMUST00000034368.6
Ctrl
chymotrypsin-like
chr6_+_30639218 6.427 ENSMUST00000031806.9
Cpa1
carboxypeptidase A1, pancreatic
chr19_+_54045182 6.193 ENSMUST00000036700.5
Adra2a
adrenergic receptor, alpha 2a
chr3_-_100489324 5.771 ENSMUST00000061455.8
Fam46c
family with sequence similarity 46, member C
chr14_+_55765956 5.748 ENSMUST00000057569.3
Ltb4r1
leukotriene B4 receptor 1
chr4_+_115059507 5.618 ENSMUST00000162489.1
Tal1
T cell acute lymphocytic leukemia 1
chr5_-_148399901 5.570 ENSMUST00000048116.8
Slc7a1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr11_-_69900930 5.475 ENSMUST00000018714.6
ENSMUST00000128046.1
2810408A11Rik

RIKEN cDNA 2810408A11 gene

chr11_-_46312220 5.142 ENSMUST00000129474.1
ENSMUST00000093166.4
ENSMUST00000165599.2
Cyfip2


cytoplasmic FMR1 interacting protein 2


chr15_-_89425795 5.134 ENSMUST00000168376.1
Cpt1b
carnitine palmitoyltransferase 1b, muscle
chr11_-_69900949 5.104 ENSMUST00000102580.3
2810408A11Rik
RIKEN cDNA 2810408A11 gene
chr11_-_116076986 4.944 ENSMUST00000153408.1
Unc13d
unc-13 homolog D (C. elegans)
chr2_+_103970115 4.894 ENSMUST00000111143.1
ENSMUST00000138815.1
Lmo2

LIM domain only 2

chr1_-_193035651 4.855 ENSMUST00000016344.7
Syt14
synaptotagmin XIV
chr1_+_135133272 4.686 ENSMUST00000167080.1
Ptpn7
protein tyrosine phosphatase, non-receptor type 7
chr14_-_51057242 4.545 ENSMUST00000089798.2
Rnase12
ribonuclease, RNase A family, 12 (non-active)
chr9_-_95845215 4.516 ENSMUST00000093800.2
Pls1
plastin 1 (I-isoform)
chr7_+_113513854 4.431 ENSMUST00000067929.8
ENSMUST00000129087.1
ENSMUST00000164745.1
ENSMUST00000136158.1
Far1



fatty acyl CoA reductase 1



chr4_+_154869585 4.280 ENSMUST00000079269.7
ENSMUST00000163732.1
ENSMUST00000080559.6
Mmel1


membrane metallo-endopeptidase-like 1


chr2_+_103970221 4.267 ENSMUST00000111140.2
ENSMUST00000111139.2
Lmo2

LIM domain only 2

chr3_+_108383829 4.176 ENSMUST00000090561.3
ENSMUST00000102629.1
ENSMUST00000128089.1
Psrc1


proline/serine-rich coiled-coil 1


chrX_+_100625737 4.103 ENSMUST00000048962.3
Kif4
kinesin family member 4
chr11_+_72961163 4.079 ENSMUST00000108486.1
ENSMUST00000108484.1
ENSMUST00000021142.7
ENSMUST00000108485.2
ENSMUST00000163326.1
Atp2a3




ATPase, Ca++ transporting, ubiquitous




chr7_+_28982832 3.920 ENSMUST00000085835.6
Map4k1
mitogen-activated protein kinase kinase kinase kinase 1
chrX_-_49797700 3.887 ENSMUST00000033442.7
ENSMUST00000114891.1
Igsf1

immunoglobulin superfamily, member 1

chr11_+_69095217 3.768 ENSMUST00000101004.2
Per1
period circadian clock 1
chr1_+_91366412 3.700 ENSMUST00000086861.5
Fam132b
family with sequence similarity 132, member B
chr2_-_181691771 3.620 ENSMUST00000108778.1
ENSMUST00000165416.1
Rgs19

regulator of G-protein signaling 19

chr2_-_32387760 3.615 ENSMUST00000050785.8
Lcn2
lipocalin 2
chr7_+_113513829 3.575 ENSMUST00000033018.8
Far1
fatty acyl CoA reductase 1
chr7_+_81858993 3.530 ENSMUST00000041890.1
Tm6sf1
transmembrane 6 superfamily member 1
chr7_-_45239108 3.515 ENSMUST00000033063.6
Cd37
CD37 antigen
chr11_+_53519725 3.438 ENSMUST00000108987.1
ENSMUST00000121334.1
ENSMUST00000117061.1
Sept8


septin 8


chr7_-_141117772 3.319 ENSMUST00000067836.7
Ano9
anoctamin 9
chr6_-_49214954 3.310 ENSMUST00000031838.7
Igf2bp3
insulin-like growth factor 2 mRNA binding protein 3
chr8_-_121907678 3.308 ENSMUST00000045557.9
Slc7a5
solute carrier family 7 (cationic amino acid transporter, y+ system), member 5
chr5_-_137741601 3.225 ENSMUST00000119498.1
ENSMUST00000061789.7
Nyap1

neuronal tyrosine-phosphorylated phosphoinositide 3-kinase adaptor 1

chr8_-_105637403 3.204 ENSMUST00000182046.1
Gm5914
predicted gene 5914
chrX_-_36989656 3.147 ENSMUST00000060474.7
ENSMUST00000053456.4
ENSMUST00000115239.3
Sept6


septin 6


chr7_-_45239041 3.121 ENSMUST00000131290.1
Cd37
CD37 antigen
chr15_+_79347534 2.959 ENSMUST00000096350.3
Maff
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)
chr9_+_108991902 2.946 ENSMUST00000147989.1
ENSMUST00000051873.8
Pfkfb4

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4

chr18_-_54990124 2.930 ENSMUST00000064763.5
Zfp608
zinc finger protein 608
chr3_+_123446913 2.856 ENSMUST00000029603.8
Prss12
protease, serine, 12 neurotrypsin (motopsin)
chr7_-_45238794 2.841 ENSMUST00000098461.1
ENSMUST00000107797.1
Cd37

CD37 antigen

chr14_+_65266701 2.810 ENSMUST00000169656.1
Fbxo16
F-box protein 16
chr8_-_85119637 2.799 ENSMUST00000098550.3
Zfp791
zinc finger protein 791
chrX_+_134295225 2.796 ENSMUST00000037687.7
Tmem35
transmembrane protein 35
chr7_-_104950441 2.699 ENSMUST00000179862.1
Gm5900
predicted pseudogene 5900
chr17_-_25952565 2.633 ENSMUST00000162431.1
A930017K11Rik
RIKEN cDNA A930017K11 gene
chr3_+_103102604 2.619 ENSMUST00000173206.1
Dennd2c
DENN/MADD domain containing 2C
chr9_+_86743641 2.607 ENSMUST00000179574.1
Prss35
protease, serine, 35
chr5_-_137741102 2.581 ENSMUST00000149512.1
Nyap1
neuronal tyrosine-phosphorylated phosphoinositide 3-kinase adaptor 1
chr9_+_75232013 2.581 ENSMUST00000036555.6
Myo5c
myosin VC
chr12_-_113422730 2.572 ENSMUST00000177715.1
ENSMUST00000103426.1
Ighm

immunoglobulin heavy constant mu

chr19_-_46327121 2.543 ENSMUST00000041391.4
ENSMUST00000096029.5
Psd

pleckstrin and Sec7 domain containing

chrX_+_159840463 2.517 ENSMUST00000112451.1
ENSMUST00000112453.2
Sh3kbp1

SH3-domain kinase binding protein 1

chr5_+_143622466 2.508 ENSMUST00000177196.1
Cyth3
cytohesin 3
chr3_+_130180882 2.456 ENSMUST00000106353.1
ENSMUST00000080335.4
Col25a1

collagen, type XXV, alpha 1

chr15_-_83033294 2.345 ENSMUST00000100377.4
Nfam1
Nfat activating molecule with ITAM motif 1
chr4_+_103619580 2.344 ENSMUST00000106827.1
Dab1
disabled 1
chr17_+_47505211 2.322 ENSMUST00000182935.1
ENSMUST00000182506.1
Ccnd3

cyclin D3

chr9_+_73044833 2.301 ENSMUST00000184146.1
ENSMUST00000034722.4
Rab27a

RAB27A, member RAS oncogene family

chr8_+_120537423 2.298 ENSMUST00000118136.1
Gse1
genetic suppressor element 1
chr11_-_8973266 2.256 ENSMUST00000154153.1
Pkd1l1
polycystic kidney disease 1 like 1
chr7_-_141443989 2.249 ENSMUST00000026580.5
Lrdd
leucine-rich and death domain containing
chr9_+_86743616 2.246 ENSMUST00000036426.6
Prss35
protease, serine, 35
chr5_-_24329556 2.222 ENSMUST00000115098.2
Kcnh2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr19_+_38931008 2.190 ENSMUST00000145051.1
Hells
helicase, lymphoid specific
chr17_+_47505043 2.157 ENSMUST00000182129.1
ENSMUST00000171031.1
Ccnd3

cyclin D3

chr4_-_43045686 2.153 ENSMUST00000107956.1
ENSMUST00000107957.1
Fam214b

family with sequence similarity 214, member B

chr11_+_96929367 2.119 ENSMUST00000062172.5
Prr15l
proline rich 15-like
chrX_-_51205990 2.116 ENSMUST00000114876.2
Mbnl3
muscleblind-like 3 (Drosophila)
chr11_-_106301801 2.112 ENSMUST00000103071.3
Gh
growth hormone
chr10_+_60346851 2.095 ENSMUST00000020301.7
ENSMUST00000105460.1
ENSMUST00000170507.1
4632428N05Rik


RIKEN cDNA 4632428N05 gene


chr19_+_38097065 2.083 ENSMUST00000067098.6
Ffar4
free fatty acid receptor 4
chr17_+_47505149 2.073 ENSMUST00000183177.1
ENSMUST00000182848.1
Ccnd3

cyclin D3

chr17_+_47505117 2.061 ENSMUST00000183044.1
ENSMUST00000037333.10
Ccnd3

cyclin D3

chr10_-_91082653 2.061 ENSMUST00000159110.1
Apaf1
apoptotic peptidase activating factor 1
chr5_+_143622440 2.057 ENSMUST00000116456.3
Cyth3
cytohesin 3
chr4_+_58943575 2.001 ENSMUST00000107554.1
Zkscan16
zinc finger with KRAB and SCAN domains 16
chr3_-_126998408 1.999 ENSMUST00000182764.1
ENSMUST00000044443.8
Ank2

ankyrin 2, brain

chr7_-_4546567 1.998 ENSMUST00000065957.5
Syt5
synaptotagmin V
chr8_-_68121527 1.995 ENSMUST00000178529.1
Gm21807
predicted gene, 21807
chr7_+_141131268 1.994 ENSMUST00000026568.8
Ptdss2
phosphatidylserine synthase 2
chr3_-_65529355 1.972 ENSMUST00000099076.3
4931440P22Rik
RIKEN cDNA 4931440P22 gene
chr15_-_75888754 1.966 ENSMUST00000184858.1
Mroh6
maestro heat-like repeat family member 6
chr7_+_43437073 1.960 ENSMUST00000070518.2
Nkg7
natural killer cell group 7 sequence
chr19_-_10304867 1.933 ENSMUST00000039327.4
Dagla
diacylglycerol lipase, alpha
chr2_-_54085542 1.933 ENSMUST00000100089.2
Rprm
reprimo, TP53 dependent G2 arrest mediator candidate
chr17_+_47726834 1.921 ENSMUST00000024782.5
ENSMUST00000144955.1
Pgc

progastricsin (pepsinogen C)

chrX_-_51205773 1.903 ENSMUST00000114875.1
Mbnl3
muscleblind-like 3 (Drosophila)
chr15_-_99457712 1.901 ENSMUST00000161948.1
Nckap5l
NCK-associated protein 5-like
chr1_+_66364623 1.878 ENSMUST00000077355.5
ENSMUST00000114012.1
Map2

microtubule-associated protein 2

chr11_-_69900886 1.803 ENSMUST00000108621.2
ENSMUST00000100969.2
2810408A11Rik

RIKEN cDNA 2810408A11 gene

chr10_-_91082704 1.800 ENSMUST00000162618.1
ENSMUST00000020157.6
ENSMUST00000160788.1
Apaf1


apoptotic peptidase activating factor 1


chr4_-_117883428 1.797 ENSMUST00000030266.5
B4galt2
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
chr16_+_17276291 1.789 ENSMUST00000164950.1
ENSMUST00000159242.1
Tmem191c

transmembrane protein 191C

chr8_+_83389846 1.760 ENSMUST00000002259.6
Clgn
calmegin
chr6_-_52158292 1.760 ENSMUST00000000964.5
ENSMUST00000120363.1
Hoxa1

homeobox A1

chrX_+_100729917 1.740 ENSMUST00000019503.7
Gdpd2
glycerophosphodiester phosphodiesterase domain containing 2
chr7_-_102100227 1.736 ENSMUST00000106937.1
Art5
ADP-ribosyltransferase 5
chr9_-_35558522 1.736 ENSMUST00000034612.5
Ddx25
DEAD (Asp-Glu-Ala-Asp) box polypeptide 25
chr1_+_87620306 1.721 ENSMUST00000169754.1
Inpp5d
inositol polyphosphate-5-phosphatase D
chrX_-_7740206 1.716 ENSMUST00000128289.1
Ccdc120
coiled-coil domain containing 120
chr8_+_83389878 1.694 ENSMUST00000109831.2
Clgn
calmegin
chr15_-_27681498 1.685 ENSMUST00000100739.3
Fam105a
family with sequence similarity 105, member A
chr16_+_17276337 1.681 ENSMUST00000159065.1
ENSMUST00000159494.1
ENSMUST00000159811.1
Tmem191c


transmembrane protein 191C


chr11_+_69965396 1.681 ENSMUST00000018713.6
Cldn7
claudin 7
chr4_+_132564051 1.678 ENSMUST00000070690.7
Ptafr
platelet-activating factor receptor
chr19_+_38930909 1.674 ENSMUST00000025965.5
Hells
helicase, lymphoid specific
chr8_-_105637350 1.668 ENSMUST00000182863.1
Gm5914
predicted gene 5914
chr3_-_127225917 1.638 ENSMUST00000182064.1
ENSMUST00000182662.1
Ank2

ankyrin 2, brain

chr9_+_107580746 1.628 ENSMUST00000148440.1
Hyal3
hyaluronoglucosaminidase 3
chr11_+_98383811 1.628 ENSMUST00000008021.2
Tcap
titin-cap
chr2_-_44927161 1.591 ENSMUST00000130991.1
Gtdc1
glycosyltransferase-like domain containing 1
chr3_-_127225847 1.585 ENSMUST00000182726.1
ENSMUST00000182779.1
Ank2

ankyrin 2, brain

chr2_+_121358591 1.583 ENSMUST00000000317.6
ENSMUST00000129130.1
Ckmt1

creatine kinase, mitochondrial 1, ubiquitous

chrX_+_135885851 1.562 ENSMUST00000180025.1
ENSMUST00000068755.7
ENSMUST00000148374.1
Bhlhb9


basic helix-loop-helix domain containing, class B9


chr6_+_48718602 1.519 ENSMUST00000127537.1
ENSMUST00000155017.2
RP24-315D19.2

GTPase IMAP family member 1

chr5_-_22344690 1.518 ENSMUST00000062372.7
ENSMUST00000161356.1
Reln

reelin

chr15_-_99457742 1.517 ENSMUST00000023747.7
Nckap5l
NCK-associated protein 5-like
chr11_+_78188422 1.514 ENSMUST00000002128.7
ENSMUST00000150941.1
Rab34

RAB34, member of RAS oncogene family

chr2_-_44927206 1.506 ENSMUST00000100127.2
Gtdc1
glycosyltransferase-like domain containing 1
chr7_-_45824750 1.493 ENSMUST00000071937.5
Kcnj14
potassium inwardly-rectifying channel, subfamily J, member 14
chrX_-_147554050 1.479 ENSMUST00000112819.2
ENSMUST00000136789.1
Lrch2

leucine-rich repeats and calponin homology (CH) domain containing 2

chr6_+_35252692 1.470 ENSMUST00000130875.1
1810058I24Rik
RIKEN cDNA 1810058I24 gene
chr11_+_96929260 1.462 ENSMUST00000054311.5
ENSMUST00000107636.3
Prr15l

proline rich 15-like

chr1_+_135836380 1.446 ENSMUST00000178204.1
Tnnt2
troponin T2, cardiac
chr2_+_121357714 1.444 ENSMUST00000125812.1
ENSMUST00000078222.2
ENSMUST00000125221.1
ENSMUST00000150271.1
Ckmt1



creatine kinase, mitochondrial 1, ubiquitous



chr11_-_6606053 1.443 ENSMUST00000045713.3
Nacad
NAC alpha domain containing
chr6_+_35252654 1.434 ENSMUST00000152147.1
1810058I24Rik
RIKEN cDNA 1810058I24 gene
chr7_+_123214776 1.421 ENSMUST00000131933.1
Slc5a11
solute carrier family 5 (sodium/glucose cotransporter), member 11
chr17_+_48264270 1.421 ENSMUST00000059873.7
ENSMUST00000154335.1
ENSMUST00000136272.1
ENSMUST00000125426.1
ENSMUST00000153420.1
Treml4




triggering receptor expressed on myeloid cells-like 4




chr11_+_54304180 1.414 ENSMUST00000108904.3
ENSMUST00000108905.3
Acsl6

acyl-CoA synthetase long-chain family member 6

chr6_-_56901870 1.391 ENSMUST00000101367.2
Nt5c3
5'-nucleotidase, cytosolic III
chr6_+_35252724 1.372 ENSMUST00000136110.1
1810058I24Rik
RIKEN cDNA 1810058I24 gene
chr11_+_54304005 1.366 ENSMUST00000000145.5
ENSMUST00000138515.1
Acsl6

acyl-CoA synthetase long-chain family member 6

chr6_+_17307040 1.341 ENSMUST00000123439.1
Cav1
caveolin 1, caveolae protein
chr6_+_115134899 1.340 ENSMUST00000009538.5
ENSMUST00000169345.1
Syn2

synapsin II

chr6_-_28831747 1.329 ENSMUST00000062304.5
Lrrc4
leucine rich repeat containing 4
chr4_+_119814495 1.321 ENSMUST00000106307.2
Hivep3
human immunodeficiency virus type I enhancer binding protein 3
chr6_+_41684414 1.312 ENSMUST00000031900.5
1700034O15Rik
RIKEN cDNA 1700034O15 gene
chr17_+_5975740 1.311 ENSMUST00000115790.1
Synj2
synaptojanin 2
chr17_+_47505073 1.303 ENSMUST00000183210.1
Ccnd3
cyclin D3
chr8_-_80739497 1.302 ENSMUST00000043359.8
Smarca5
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
chr11_+_96323253 1.298 ENSMUST00000093944.3
Hoxb3
homeobox B3
chrX_-_136085206 1.293 ENSMUST00000138878.1
ENSMUST00000080929.6
Nxf3

nuclear RNA export factor 3

chrX_+_100730178 1.292 ENSMUST00000113744.1
Gdpd2
glycerophosphodiester phosphodiesterase domain containing 2
chr7_-_115824699 1.261 ENSMUST00000169129.1
Sox6
SRY-box containing gene 6
chr12_+_51348370 1.259 ENSMUST00000121521.1
G2e3
G2/M-phase specific E3 ubiquitin ligase
chr11_-_70220776 1.240 ENSMUST00000141290.1
Slc16a13
solute carrier family 16 (monocarboxylic acid transporters), member 13
chr9_-_59146210 1.229 ENSMUST00000085631.2
Gm7589
predicted gene 7589
chr17_+_21383725 1.227 ENSMUST00000056107.4
ENSMUST00000162659.1
Zfp677

zinc finger protein 677

chr7_+_25267669 1.226 ENSMUST00000169266.1
Cic
capicua homolog (Drosophila)
chr15_+_103453782 1.206 ENSMUST00000047405.7
Nckap1l
NCK associated protein 1 like
chr12_-_27342696 1.195 ENSMUST00000079063.5
Sox11
SRY-box containing gene 11
chr2_+_24186469 1.194 ENSMUST00000057567.2
Il1f9
interleukin 1 family, member 9
chr7_-_35396708 1.193 ENSMUST00000154597.1
ENSMUST00000032704.5
C230052I12Rik

RIKEN cDNA C230052I12 gene

chr7_-_140082246 1.163 ENSMUST00000166758.2
Caly
calcyon neuron-specific vesicular protein
chr6_+_4504814 1.158 ENSMUST00000141483.1
Col1a2
collagen, type I, alpha 2
chr17_+_32036098 1.157 ENSMUST00000081339.6
Rrp1b
ribosomal RNA processing 1 homolog B (S. cerevisiae)
chr11_-_120598346 1.149 ENSMUST00000026125.2
Alyref
Aly/REF export factor
chr15_-_63997969 1.147 ENSMUST00000164532.1
Fam49b
family with sequence similarity 49, member B
chr1_-_178337774 1.147 ENSMUST00000037748.7
Hnrnpu
heterogeneous nuclear ribonucleoprotein U
chr11_+_20647149 1.141 ENSMUST00000109585.1
Sertad2
SERTA domain containing 2
chr5_-_143292356 1.139 ENSMUST00000180336.1
Zfp853
zinc finger protein 853
chr12_+_51348019 1.139 ENSMUST00000054308.6
G2e3
G2/M-phase specific E3 ubiquitin ligase
chrX_+_42151002 1.121 ENSMUST00000123245.1
Stag2
stromal antigen 2
chr6_+_54681687 1.117 ENSMUST00000046276.6
2410066E13Rik
RIKEN cDNA 2410066E13 gene
chr11_-_70220794 1.117 ENSMUST00000159867.1
Slc16a13
solute carrier family 16 (monocarboxylic acid transporters), member 13
chr1_-_167285110 1.116 ENSMUST00000027839.8
Uck2
uridine-cytidine kinase 2
chr8_+_125669818 1.095 ENSMUST00000053078.3
Map10
microtubule-associated protein 10
chr7_-_44748617 1.092 ENSMUST00000060270.6
Zfp473
zinc finger protein 473
chr9_-_96437434 1.087 ENSMUST00000070500.2
BC043934
cDNA sequence BC043934
chr13_+_118714678 1.059 ENSMUST00000022246.8
Fgf10
fibroblast growth factor 10
chr1_+_63273261 1.059 ENSMUST00000114132.1
ENSMUST00000126932.1
Zdbf2

zinc finger, DBF-type containing 2

chr3_+_126597299 1.058 ENSMUST00000106400.2
ENSMUST00000106401.1
Camk2d

calcium/calmodulin-dependent protein kinase II, delta

chr10_-_14544972 1.028 ENSMUST00000041168.4
Gpr126
G protein-coupled receptor 126
chr11_-_70220969 1.026 ENSMUST00000060010.2
Slc16a13
solute carrier family 16 (monocarboxylic acid transporters), member 13
chr3_-_95306794 1.026 ENSMUST00000107183.1
ENSMUST00000164406.1
ENSMUST00000123365.1
Anxa9


annexin A9


chr5_+_113490447 1.025 ENSMUST00000094452.3
Wscd2
WSC domain containing 2
chr18_+_82914632 0.991 ENSMUST00000071233.6
Zfp516
zinc finger protein 516
chr6_-_28830345 0.986 ENSMUST00000171353.1
Lrrc4
leucine rich repeat containing 4
chr1_+_93373874 0.982 ENSMUST00000058682.4
Ano7
anoctamin 7
chr5_+_17574726 0.978 ENSMUST00000169603.1
Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr18_+_36793918 0.976 ENSMUST00000001419.8
Zmat2
zinc finger, matrin type 2
chr19_-_6925367 0.956 ENSMUST00000057716.4
Tex40
testis expressed 40
chr7_-_113369326 0.942 ENSMUST00000047091.7
ENSMUST00000119278.1
Btbd10

BTB (POZ) domain containing 10


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 8.3 GO:0002215 defense response to nematode(GO:0002215)
1.9 5.6 GO:0060217 hemangioblast cell differentiation(GO:0060217)
1.4 10.9 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
1.3 8.0 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
1.2 3.6 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
1.1 5.7 GO:0061737 leukotriene signaling pathway(GO:0061737)
1.1 4.5 GO:1902896 terminal web assembly(GO:1902896)
1.1 10.1 GO:0010587 miRNA catabolic process(GO:0010587)
1.1 3.3 GO:2001226 negative regulation of chloride transport(GO:2001226)
1.0 6.2 GO:0035624 receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
1.0 8.0 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
1.0 3.9 GO:0097477 lateral motor column neuron migration(GO:0097477)
0.9 9.5 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
0.9 2.6 GO:0002343 peripheral B cell selection(GO:0002343) B cell affinity maturation(GO:0002344)
0.8 3.8 GO:0097167 circadian regulation of translation(GO:0097167)
0.8 2.3 GO:0003127 detection of nodal flow(GO:0003127) detection of endogenous stimulus(GO:0009726)
0.7 8.4 GO:0034242 negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.7 5.6 GO:1903826 arginine transmembrane transport(GO:1903826)
0.6 4.9 GO:0061789 dense core granule priming(GO:0061789)
0.6 9.2 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.6 1.8 GO:0021570 rhombomere 4 development(GO:0021570)
0.6 5.2 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.6 1.1 GO:2000567 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.6 1.1 GO:2000373 regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
0.6 1.7 GO:1904306 positive regulation of gastro-intestinal system smooth muscle contraction(GO:1904306)
0.6 2.2 GO:1902303 negative regulation of potassium ion export(GO:1902303)
0.6 3.9 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.5 5.2 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.5 4.1 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.5 2.0 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.5 2.5 GO:1903609 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.5 1.9 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.5 3.9 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.5 1.4 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.5 2.8 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
0.5 2.3 GO:0097278 complement-dependent cytotoxicity(GO:0097278)
0.5 1.8 GO:0061386 closure of optic fissure(GO:0061386)
0.4 9.9 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.4 1.7 GO:0045659 negative regulation of neutrophil differentiation(GO:0045659)
0.4 2.1 GO:1905169 protein localization to phagocytic vesicle(GO:1905161) regulation of protein localization to phagocytic vesicle(GO:1905169) positive regulation of protein localization to phagocytic vesicle(GO:1905171)
0.4 1.9 GO:0002803 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.4 2.2 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.4 1.1 GO:0071338 bronchiole development(GO:0060435) secretion by lung epithelial cell involved in lung growth(GO:0061033) white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350) positive regulation of hair follicle cell proliferation(GO:0071338)
0.4 2.5 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.3 2.9 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.3 3.0 GO:0090527 actin filament reorganization(GO:0090527)
0.3 1.2 GO:0070358 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376) actin polymerization-dependent cell motility(GO:0070358)
0.3 2.3 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.3 1.6 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.3 1.6 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.3 11.1 GO:0048821 erythrocyte development(GO:0048821)
0.3 0.5 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.2 1.0 GO:0061589 calcium activated phosphatidylserine scrambling(GO:0061589)
0.2 1.0 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.2 0.7 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.2 1.4 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.2 1.1 GO:0008655 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.2 0.7 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.2 11.0 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.2 6.2 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.2 0.6 GO:0034184 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.2 1.3 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.2 0.7 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.2 2.3 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.2 0.5 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.2 0.2 GO:0001575 globoside metabolic process(GO:0001575)
0.2 0.7 GO:1902514 regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.2 1.3 GO:0016584 nucleosome positioning(GO:0016584)
0.2 13.2 GO:0015909 long-chain fatty acid transport(GO:0015909)
0.2 0.5 GO:0019045 latent virus replication(GO:0019045) release from viral latency(GO:0019046)
0.2 0.5 GO:2000328 regulation of T-helper 17 cell lineage commitment(GO:2000328)
0.2 0.9 GO:0097527 necroptotic signaling pathway(GO:0097527)
0.2 0.3 GO:1902608 regulation of large conductance calcium-activated potassium channel activity(GO:1902606) positive regulation of large conductance calcium-activated potassium channel activity(GO:1902608)
0.1 2.1 GO:0090031 positive regulation of steroid hormone biosynthetic process(GO:0090031)
0.1 2.6 GO:0032252 secretory granule localization(GO:0032252)
0.1 0.4 GO:1902277 negative regulation of pancreatic amylase secretion(GO:1902277)
0.1 0.4 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.1 0.9 GO:0036006 response to macrophage colony-stimulating factor(GO:0036005) cellular response to macrophage colony-stimulating factor stimulus(GO:0036006)
0.1 0.3 GO:0042823 vitamin B6 biosynthetic process(GO:0042819) pyridoxal phosphate biosynthetic process(GO:0042823)
0.1 1.8 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 2.9 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 1.1 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.1 0.6 GO:0048496 maintenance of animal organ identity(GO:0048496)
0.1 3.4 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.1 0.4 GO:0003349 epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
0.1 1.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 0.7 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 0.3 GO:0071288 cellular response to mercury ion(GO:0071288)
0.1 0.7 GO:0070494 regulation of thrombin-activated receptor signaling pathway(GO:0070494) negative regulation of thrombin-activated receptor signaling pathway(GO:0070495)
0.1 0.3 GO:1900248 negative regulation of cytoplasmic translational elongation(GO:1900248)
0.1 1.4 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 0.4 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.1 0.3 GO:0021852 pyramidal neuron migration(GO:0021852)
0.1 0.5 GO:2000224 regulation of testosterone biosynthetic process(GO:2000224)
0.1 0.5 GO:2001205 negative regulation of osteoclast development(GO:2001205)
0.1 0.6 GO:0061577 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577)
0.1 5.1 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.1 4.7 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.1 5.7 GO:0007019 microtubule depolymerization(GO:0007019)
0.1 1.0 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 0.7 GO:0036506 maintenance of unfolded protein(GO:0036506) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.1 1.2 GO:0043589 skin morphogenesis(GO:0043589)
0.1 1.7 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.1 0.3 GO:1903789 regulation of amino acid transmembrane transport(GO:1903789) regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.1 1.2 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.1 0.6 GO:0048539 bone marrow development(GO:0048539)
0.1 1.6 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.1 3.5 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.1 2.1 GO:0050912 detection of chemical stimulus involved in sensory perception of taste(GO:0050912)
0.1 0.2 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979)
0.1 0.4 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.1 0.3 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.1 2.4 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.1 0.2 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 3.0 GO:0015804 neutral amino acid transport(GO:0015804)
0.1 0.8 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.1 1.4 GO:1904659 glucose transmembrane transport(GO:1904659)
0.1 0.6 GO:0099628 receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
0.1 0.4 GO:0048146 positive regulation of fibroblast proliferation(GO:0048146)
0.0 1.2 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.6 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 1.4 GO:0010107 potassium ion import(GO:0010107)
0.0 4.5 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 3.5 GO:0099132 ATP hydrolysis coupled cation transmembrane transport(GO:0099132)
0.0 1.6 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 1.8 GO:0021680 cerebellar Purkinje cell layer development(GO:0021680)
0.0 0.6 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 5.3 GO:0014065 phosphatidylinositol 3-kinase signaling(GO:0014065)
0.0 4.2 GO:0051028 mRNA transport(GO:0051028)
0.0 0.9 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.0 4.9 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.8 GO:0042711 maternal behavior(GO:0042711)
0.0 0.7 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 1.1 GO:0030308 negative regulation of cell growth(GO:0030308)
0.0 0.6 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.0 0.3 GO:0043922 positive regulation of vascular permeability(GO:0043117) negative regulation by host of viral transcription(GO:0043922)
0.0 3.1 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 1.0 GO:0009409 response to cold(GO:0009409)
0.0 0.5 GO:2001240 negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.2 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.4 GO:2000637 positive regulation of gene silencing by miRNA(GO:2000637)
0.0 0.9 GO:0031638 zymogen activation(GO:0031638)
0.0 0.8 GO:0015701 bicarbonate transport(GO:0015701)
0.0 1.2 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.1 GO:0060214 endocardium formation(GO:0060214)
0.0 0.9 GO:0050919 negative chemotaxis(GO:0050919)
0.0 1.9 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.3 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.3 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.3 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.0 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.0 1.2 GO:0099643 neurotransmitter secretion(GO:0007269) signal release from synapse(GO:0099643)
0.0 1.8 GO:0090501 RNA phosphodiester bond hydrolysis(GO:0090501)
0.0 0.1 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.4 GO:0001919 regulation of receptor recycling(GO:0001919)
0.0 0.5 GO:0043627 response to estrogen(GO:0043627)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 5.6 GO:0033193 Lsd1/2 complex(GO:0033193)
1.0 3.1 GO:0005940 septin ring(GO:0005940)
1.0 3.9 GO:0043293 apoptosome(GO:0043293)
0.9 12.4 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.7 11.0 GO:0042581 specific granule(GO:0042581)
0.7 7.2 GO:0033093 Weibel-Palade body(GO:0033093)
0.6 4.5 GO:1990357 terminal web(GO:1990357)
0.6 2.2 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.4 1.3 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.4 9.8 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.4 2.0 GO:1990769 proximal neuron projection(GO:1990769)
0.4 1.2 GO:0005584 collagen type I trimer(GO:0005584)
0.4 2.6 GO:0019815 B cell receptor complex(GO:0019815)
0.3 2.5 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.3 8.0 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.2 1.4 GO:1990584 cardiac Troponin complex(GO:1990584)
0.2 3.2 GO:0043083 synaptic cleft(GO:0043083)
0.2 1.9 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.2 0.6 GO:0035061 interchromatin granule(GO:0035061)
0.2 1.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.2 2.5 GO:0036501 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) UFD1-NPL4 complex(GO:0036501)
0.2 9.7 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 5.6 GO:0043034 costamere(GO:0043034)
0.1 1.8 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.1 0.6 GO:1990696 USH2 complex(GO:1990696)
0.1 1.5 GO:0005677 chromatin silencing complex(GO:0005677)
0.1 0.7 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.1 1.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 7.2 GO:0001772 immunological synapse(GO:0001772)
0.1 0.3 GO:0032127 dense core granule membrane(GO:0032127)
0.1 3.8 GO:0005721 pericentric heterochromatin(GO:0005721)
0.1 0.7 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1 1.2 GO:0031209 SCAR complex(GO:0031209)
0.1 9.8 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 1.9 GO:0043196 varicosity(GO:0043196)
0.1 1.2 GO:0043194 axon initial segment(GO:0043194)
0.1 1.7 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 4.1 GO:0045171 intercellular bridge(GO:0045171)
0.1 0.7 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 1.1 GO:0033391 chromatoid body(GO:0033391)
0.1 0.6 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 1.1 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 1.1 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 11.0 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 2.8 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.5 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.7 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 6.7 GO:0030139 endocytic vesicle(GO:0030139)
0.0 0.3 GO:0090724 central region of growth cone(GO:0090724)
0.0 0.2 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.6 GO:0036038 MKS complex(GO:0036038)
0.0 0.6 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 1.0 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.0 7.4 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 1.1 GO:0015030 Cajal body(GO:0015030)
0.0 1.3 GO:0031201 SNARE complex(GO:0031201)
0.0 2.3 GO:0030863 cortical cytoskeleton(GO:0030863)
0.0 0.8 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 1.7 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 0.3 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.5 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 3.6 GO:0001726 ruffle(GO:0001726)
0.0 0.6 GO:0034451 centriolar satellite(GO:0034451)
0.0 7.4 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 2.6 GO:0030027 lamellipodium(GO:0030027)
0.0 0.4 GO:0035371 microtubule plus-end(GO:0035371)
0.0 5.8 GO:0030141 secretory granule(GO:0030141)
0.0 3.0 GO:0044455 mitochondrial membrane part(GO:0044455)
0.0 0.1 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.7 GO:0060076 excitatory synapse(GO:0060076)
0.0 0.6 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.6 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.5 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.4 GO:0090544 BAF-type complex(GO:0090544)
0.0 0.7 GO:0031519 PcG protein complex(GO:0031519)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 12.9 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
1.6 8.0 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
1.5 6.2 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
1.4 5.7 GO:0004974 leukotriene receptor activity(GO:0004974)
1.4 10.9 GO:0002951 leukotriene-C(4) hydrolase(GO:0002951)
1.0 9.8 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.8 9.5 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.7 5.6 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.6 1.8 GO:0004461 lactose synthase activity(GO:0004461)
0.5 1.6 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.5 3.0 GO:0004111 creatine kinase activity(GO:0004111)
0.5 8.0 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
0.5 2.5 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.5 2.4 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.4 3.9 GO:0034711 inhibin binding(GO:0034711)
0.4 13.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.4 1.1 GO:0023030 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.4 2.2 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.3 3.0 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.3 1.7 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.3 2.9 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.3 1.6 GO:0051373 FATZ binding(GO:0051373)
0.3 16.8 GO:0070888 E-box binding(GO:0070888)
0.3 1.7 GO:0051425 PTB domain binding(GO:0051425)
0.3 1.1 GO:0034046 poly(G) binding(GO:0034046)
0.3 2.1 GO:0005131 growth hormone receptor binding(GO:0005131)
0.3 1.5 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.2 2.0 GO:0003882 CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:0003882)
0.2 3.2 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.2 2.2 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.2 1.9 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.2 2.9 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.2 1.1 GO:0004849 uridine kinase activity(GO:0004849)
0.2 2.1 GO:0008527 taste receptor activity(GO:0008527)
0.2 1.4 GO:0031013 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.2 4.4 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229) intracellular chloride channel activity(GO:0061778)
0.2 0.9 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.2 6.2 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.2 8.6 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.2 1.9 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.2 7.7 GO:0050699 WW domain binding(GO:0050699)
0.2 0.5 GO:0022850 serotonin-gated cation-selective channel activity(GO:0022850)
0.2 1.8 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.1 0.4 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 0.7 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.1 1.2 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 2.8 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 3.3 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 0.9 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 4.1 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 3.5 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 8.4 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 1.8 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 1.2 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.1 1.4 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 1.9 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.8 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 0.5 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.1 2.5 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 3.5 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 6.2 GO:0004601 peroxidase activity(GO:0004601)
0.1 0.3 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.1 2.1 GO:0017160 Ral GTPase binding(GO:0017160)
0.1 2.3 GO:0031489 myosin V binding(GO:0031489)
0.1 0.7 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 0.6 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 11.5 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1 0.6 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.1 1.4 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 2.1 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.1 4.3 GO:0030507 spectrin binding(GO:0030507)
0.1 0.4 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 3.0 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.1 3.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 0.3 GO:0004966 galanin receptor activity(GO:0004966)
0.1 0.5 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.1 0.1 GO:0042610 CD8 receptor binding(GO:0042610)
0.1 2.8 GO:0001540 amyloid-beta binding(GO:0001540)
0.1 0.3 GO:0005308 creatine transmembrane transporter activity(GO:0005308)
0.1 1.9 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.0 2.3 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.3 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.0 0.9 GO:0005123 death receptor binding(GO:0005123)
0.0 0.1 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.0 0.8 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.8 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.7 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 6.9 GO:0004386 helicase activity(GO:0004386)
0.0 0.6 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.5 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.5 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.6 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 1.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.4 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.3 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 4.2 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 3.4 GO:0015293 symporter activity(GO:0015293)
0.0 3.9 GO:0004519 endonuclease activity(GO:0004519)
0.0 0.5 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 3.1 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 1.2 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.3 GO:0010181 FMN binding(GO:0010181)
0.0 1.3 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 1.2 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 2.9 GO:0051015 actin filament binding(GO:0051015)
0.0 0.6 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.3 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.6 GO:0017022 myosin binding(GO:0017022)
0.0 0.8 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 1.1 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.5 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164) tumor necrosis factor receptor superfamily binding(GO:0032813)
0.0 0.1 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.4 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 2.0 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.0 0.3 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 2.7 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.7 GO:0048365 Rac GTPase binding(GO:0048365)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.9 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
0.2 4.7 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.2 3.8 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.2 3.9 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.2 8.8 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.1 2.5 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.1 6.2 ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY PI3K Pathway
0.1 8.2 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 3.5 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 2.5 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.1 4.8 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 3.4 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 2.5 PID_IFNG_PATHWAY IFN-gamma pathway
0.1 2.5 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 3.2 PID_MET_PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.4 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.0 1.9 PID_LKB1_PATHWAY LKB1 signaling events
0.0 1.9 NABA_COLLAGENS Genes encoding collagen proteins
0.0 0.7 PID_VEGFR1_2_PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.6 ST_GA12_PATHWAY G alpha 12 Pathway
0.0 0.7 PID_RHOA_PATHWAY RhoA signaling pathway
0.0 1.1 PID_PLK1_PATHWAY PLK1 signaling events
0.0 0.2 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.9 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 10.8 REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.4 8.0 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.3 10.9 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.2 8.9 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 9.9 REACTOME_G1_PHASE Genes involved in G1 Phase
0.2 9.3 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.2 6.2 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 2.0 REACTOME_REGULATION_OF_INSULIN_SECRETION Genes involved in Regulation of Insulin Secretion
0.1 0.6 REACTOME_INHIBITION_OF_INSULIN_SECRETION_BY_ADRENALINE_NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1 1.3 REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.1 2.5 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 3.4 REACTOME_PEROXISOMAL_LIPID_METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 2.3 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 3.9 REACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.1 2.3 REACTOME_UNBLOCKING_OF_NMDA_RECEPTOR_GLUTAMATE_BINDING_AND_ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.1 2.1 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 1.3 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 0.7 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 1.4 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism
0.1 1.8 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.1 1.1 REACTOME_PYRIMIDINE_METABOLISM Genes involved in Pyrimidine metabolism
0.1 2.3 REACTOME_INWARDLY_RECTIFYING_K_CHANNELS Genes involved in Inwardly rectifying K+ channels
0.1 3.8 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 2.9 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.1 2.5 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.1 3.1 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.3 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 0.5 REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 7.1 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 2.3 REACTOME_INTERFERON_GAMMA_SIGNALING Genes involved in Interferon gamma signaling
0.0 0.7 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.0 0.5 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.0 0.7 REACTOME_AMYLOIDS Genes involved in Amyloids
0.0 1.8 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.8 REACTOME_FGFR1_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 2.3 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 0.9 REACTOME_CA_DEPENDENT_EVENTS Genes involved in Ca-dependent events
0.0 0.7 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 1.1 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.0 1.3 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.2 REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.9 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.2 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 1.7 REACTOME_MRNA_SPLICING Genes involved in mRNA Splicing