Motif ID: Tcf3

Z-value: 1.373


Transcription factors associated with Tcf3:

Gene SymbolEntrez IDGene Name
Tcf3 ENSMUSG00000020167.8 Tcf3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tcf3mm10_v2_chr10_-_80433615_804336550.853.4e-11Click!


Activity profile for motif Tcf3.

activity profile for motif Tcf3


Sorted Z-values histogram for motif Tcf3

Sorted Z-values for motif Tcf3



Network of associatons between targets according to the STRING database.



First level regulatory network of Tcf3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_+_23139064 19.575 ENSMUST00000033947.8
Ank1
ankyrin 1, erythroid
chr8_+_23139030 18.238 ENSMUST00000121075.1
Ank1
ankyrin 1, erythroid
chr12_+_109459843 15.109 ENSMUST00000173812.1
Dlk1
delta-like 1 homolog (Drosophila)
chr2_+_131186942 11.800 ENSMUST00000028804.8
ENSMUST00000079857.8
Cdc25b

cell division cycle 25B

chr11_-_102365111 8.799 ENSMUST00000006749.9
Slc4a1
solute carrier family 4 (anion exchanger), member 1
chr6_+_30639218 8.763 ENSMUST00000031806.9
Cpa1
carboxypeptidase A1, pancreatic
chr6_-_41377604 8.555 ENSMUST00000096003.5
Prss3
protease, serine, 3
chr7_-_17056669 8.421 ENSMUST00000037762.4
Hif3a
hypoxia inducible factor 3, alpha subunit
chr2_-_170406501 7.949 ENSMUST00000154650.1
Bcas1
breast carcinoma amplified sequence 1
chr1_+_75507077 7.949 ENSMUST00000037330.4
Inha
inhibin alpha
chr11_+_115900125 7.696 ENSMUST00000142089.1
ENSMUST00000131566.1
Smim5

small integral membrane protein 5

chr11_+_115899943 7.649 ENSMUST00000152171.1
Smim5
small integral membrane protein 5
chr2_+_153492790 7.229 ENSMUST00000109783.1
4930404H24Rik
RIKEN cDNA 4930404H24 gene
chr6_+_41458923 7.104 ENSMUST00000031910.7
Prss1
protease, serine, 1 (trypsin 1)
chr11_-_120648104 7.051 ENSMUST00000026134.2
Myadml2
myeloid-associated differentiation marker-like 2
chr11_-_53480178 7.021 ENSMUST00000104955.2
Sowaha
sosondowah ankyrin repeat domain family member A
chr17_-_26201328 6.803 ENSMUST00000025019.2
Arhgdig
Rho GDP dissociation inhibitor (GDI) gamma
chr6_+_29694204 6.788 ENSMUST00000046750.7
ENSMUST00000115250.3
Tspan33

tetraspanin 33

chr2_+_84734050 6.743 ENSMUST00000090729.2
Ypel4
yippee-like 4 (Drosophila)
chr10_-_19851459 6.574 ENSMUST00000059805.4
Slc35d3
solute carrier family 35, member D3
chr3_-_152166230 6.360 ENSMUST00000046614.9
Gipc2
GIPC PDZ domain containing family, member 2
chr19_-_15924560 6.149 ENSMUST00000162053.1
Psat1
phosphoserine aminotransferase 1
chr6_+_41392356 6.115 ENSMUST00000049079.7
Gm5771
predicted gene 5771
chr1_-_75506331 5.980 ENSMUST00000113567.2
ENSMUST00000113565.2
Obsl1

obscurin-like 1

chr2_-_28563362 5.935 ENSMUST00000028161.5
Cel
carboxyl ester lipase
chr17_-_87797994 5.871 ENSMUST00000055221.7
Kcnk12
potassium channel, subfamily K, member 12
chr6_-_41314700 5.762 ENSMUST00000064324.5
Try5
trypsin 5
chr17_-_26201363 5.759 ENSMUST00000121959.1
Arhgdig
Rho GDP dissociation inhibitor (GDI) gamma
chr3_-_20275659 5.710 ENSMUST00000011607.5
Cpb1
carboxypeptidase B1 (tissue)
chr16_+_87553313 5.688 ENSMUST00000026700.7
Map3k7cl
Map3k7 C-terminal like
chr17_-_43502773 5.650 ENSMUST00000024707.8
ENSMUST00000117137.1
Mep1a

meprin 1 alpha

chr9_-_39604124 5.528 ENSMUST00000042485.4
ENSMUST00000141370.1
AW551984

expressed sequence AW551984

chr8_+_23139157 5.408 ENSMUST00000174435.1
Ank1
ankyrin 1, erythroid
chr12_-_76709997 5.368 ENSMUST00000166101.1
Sptb
spectrin beta, erythrocytic
chr8_+_3665747 5.309 ENSMUST00000014118.2
1810033B17Rik
RIKEN cDNA 1810033B17 gene
chr11_+_53519871 5.250 ENSMUST00000120878.2
Sept8
septin 8
chr5_+_123076275 5.235 ENSMUST00000067505.8
ENSMUST00000111619.3
ENSMUST00000160344.1
Tmem120b


transmembrane protein 120B


chr2_+_91035613 5.202 ENSMUST00000111445.3
ENSMUST00000111446.3
ENSMUST00000050323.5
Rapsn


receptor-associated protein of the synapse


chr14_+_70457447 5.128 ENSMUST00000003561.3
Phyhip
phytanoyl-CoA hydroxylase interacting protein
chr17_-_35027909 5.050 ENSMUST00000040151.2
Sapcd1
suppressor APC domain containing 1
chr11_+_53519920 4.956 ENSMUST00000147912.1
Sept8
septin 8
chr8_-_105933832 4.951 ENSMUST00000034368.6
Ctrl
chymotrypsin-like
chr6_+_40964760 4.909 ENSMUST00000076638.5
1810009J06Rik
RIKEN cDNA 1810009J06 gene
chr13_-_55528511 4.881 ENSMUST00000047877.4
Dok3
docking protein 3
chr5_-_73191848 4.825 ENSMUST00000176910.1
Fryl
furry homolog-like (Drosophila)
chr8_+_94977101 4.742 ENSMUST00000179619.1
Gpr56
G protein-coupled receptor 56
chr11_+_61956779 4.575 ENSMUST00000049836.7
Specc1
sperm antigen with calponin homology and coiled-coil domains 1
chr4_-_133872997 4.555 ENSMUST00000137486.2
Rps6ka1
ribosomal protein S6 kinase polypeptide 1
chr3_-_100489324 4.521 ENSMUST00000061455.8
Fam46c
family with sequence similarity 46, member C
chr5_-_107726017 4.398 ENSMUST00000159263.2
Gfi1
growth factor independent 1
chr19_+_6105774 4.390 ENSMUST00000044451.3
Naaladl1
N-acetylated alpha-linked acidic dipeptidase-like 1
chr7_+_142441808 4.375 ENSMUST00000105971.1
ENSMUST00000145287.1
Tnni2

troponin I, skeletal, fast 2

chr7_+_45216671 4.286 ENSMUST00000134420.1
Tead2
TEA domain family member 2
chr1_+_74791516 4.283 ENSMUST00000006718.8
Wnt10a
wingless related MMTV integration site 10a
chr2_+_103969528 4.267 ENSMUST00000123437.1
ENSMUST00000163256.1
Lmo2

LIM domain only 2

chr1_+_135132693 4.142 ENSMUST00000049449.4
Ptpn7
protein tyrosine phosphatase, non-receptor type 7
chr7_+_122289297 4.124 ENSMUST00000064989.5
ENSMUST00000064921.4
Prkcb

protein kinase C, beta

chr18_+_34840575 4.109 ENSMUST00000043484.7
Reep2
receptor accessory protein 2
chr19_+_60755947 4.066 ENSMUST00000088237.4
Nanos1
nanos homolog 1 (Drosophila)
chr11_-_107716517 4.057 ENSMUST00000021065.5
Cacng1
calcium channel, voltage-dependent, gamma subunit 1
chr9_-_21963568 4.038 ENSMUST00000006397.5
Epor
erythropoietin receptor
chr8_+_71597648 4.036 ENSMUST00000143662.1
Fam129c
family with sequence similarity 129, member C
chr7_+_67952817 4.021 ENSMUST00000005671.8
Igf1r
insulin-like growth factor I receptor
chr8_+_105518736 4.020 ENSMUST00000034363.5
Hsd11b2
hydroxysteroid 11-beta dehydrogenase 2
chr16_-_16869255 4.016 ENSMUST00000075017.4
Vpreb1
pre-B lymphocyte gene 1
chr1_+_135133272 3.991 ENSMUST00000167080.1
Ptpn7
protein tyrosine phosphatase, non-receptor type 7
chr10_+_14523062 3.963 ENSMUST00000096020.5
Gm10335
predicted gene 10335
chr2_+_14873656 3.908 ENSMUST00000114718.1
ENSMUST00000114719.1
Cacnb2

calcium channel, voltage-dependent, beta 2 subunit

chr3_-_116253467 3.803 ENSMUST00000090473.5
Gpr88
G-protein coupled receptor 88
chr7_+_142442330 3.791 ENSMUST00000149529.1
Tnni2
troponin I, skeletal, fast 2
chr11_+_104577281 3.759 ENSMUST00000106956.3
Myl4
myosin, light polypeptide 4
chr12_-_17176888 3.666 ENSMUST00000170580.1
Kcnf1
potassium voltage-gated channel, subfamily F, member 1
chrX_+_160390684 3.609 ENSMUST00000112408.2
ENSMUST00000112402.1
ENSMUST00000112401.1
ENSMUST00000112400.1
ENSMUST00000112405.2
ENSMUST00000112404.2
ENSMUST00000146805.1
Gpr64






G protein-coupled receptor 64






chr4_+_45184815 3.569 ENSMUST00000134280.1
ENSMUST00000044773.5
Frmpd1

FERM and PDZ domain containing 1

chr13_-_95444827 3.523 ENSMUST00000045583.7
Crhbp
corticotropin releasing hormone binding protein
chr11_-_46312220 3.419 ENSMUST00000129474.1
ENSMUST00000093166.4
ENSMUST00000165599.2
Cyfip2


cytoplasmic FMR1 interacting protein 2


chr8_+_45885479 3.412 ENSMUST00000034053.5
Pdlim3
PDZ and LIM domain 3
chrX_-_139871637 3.397 ENSMUST00000033811.7
ENSMUST00000087401.5
Morc4

microrchidia 4

chr11_+_76998595 3.299 ENSMUST00000108402.2
ENSMUST00000021195.4
Slc6a4

solute carrier family 6 (neurotransmitter transporter, serotonin), member 4

chr4_-_43523388 3.289 ENSMUST00000107913.3
ENSMUST00000030184.5
Tpm2

tropomyosin 2, beta

chr8_-_122699066 3.263 ENSMUST00000127984.1
Cbfa2t3
core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)
chr11_+_104576965 3.218 ENSMUST00000106957.1
Myl4
myosin, light polypeptide 4
chr11_-_69605829 3.217 ENSMUST00000047889.6
Atp1b2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr2_+_103970115 3.196 ENSMUST00000111143.1
ENSMUST00000138815.1
Lmo2

LIM domain only 2

chr9_-_107985863 3.188 ENSMUST00000048568.4
Fam212a
family with sequence similarity 212, member A
chr5_+_21543525 3.162 ENSMUST00000035651.4
Lrrc17
leucine rich repeat containing 17
chr7_+_142471838 3.130 ENSMUST00000038946.2
Lsp1
lymphocyte specific 1
chr12_-_115790884 3.109 ENSMUST00000081809.5
Ighv1-73
immunoglobulin heavy variable 1-73
chr5_-_113830422 3.104 ENSMUST00000100874.4
Selplg
selectin, platelet (p-selectin) ligand
chr12_-_79007276 3.074 ENSMUST00000056660.6
ENSMUST00000174721.1
Tmem229b

transmembrane protein 229B

chr7_+_142472080 3.003 ENSMUST00000105966.1
Lsp1
lymphocyte specific 1
chr17_+_75178797 3.003 ENSMUST00000112516.1
ENSMUST00000135447.1
Ltbp1

latent transforming growth factor beta binding protein 1

chr12_+_9574437 2.996 ENSMUST00000057021.7
Osr1
odd-skipped related 1 (Drosophila)
chr7_-_25005895 2.983 ENSMUST00000102858.3
ENSMUST00000080882.6
Atp1a3

ATPase, Na+/K+ transporting, alpha 3 polypeptide

chr7_+_19291070 2.972 ENSMUST00000108468.3
Rtn2
reticulon 2 (Z-band associated protein)
chr19_+_47178820 2.956 ENSMUST00000111808.3
Neurl1a
neuralized homolog 1A (Drosophila)
chr4_-_43523746 2.953 ENSMUST00000150592.1
Tpm2
tropomyosin 2, beta
chrX_+_101449078 2.942 ENSMUST00000033674.5
Itgb1bp2
integrin beta 1 binding protein 2
chr2_-_164779721 2.929 ENSMUST00000103095.4
Tnnc2
troponin C2, fast
chr7_+_19411086 2.806 ENSMUST00000003643.1
Ckm
creatine kinase, muscle
chr17_+_29318850 2.802 ENSMUST00000114701.2
Pi16
peptidase inhibitor 16
chr9_+_121777607 2.766 ENSMUST00000098272.2
Klhl40
kelch-like 40
chr2_+_103970221 2.764 ENSMUST00000111140.2
ENSMUST00000111139.2
Lmo2

LIM domain only 2

chr13_-_117025505 2.750 ENSMUST00000022239.6
Parp8
poly (ADP-ribose) polymerase family, member 8
chr18_+_60963517 2.692 ENSMUST00000115295.2
ENSMUST00000039904.6
Camk2a

calcium/calmodulin-dependent protein kinase II alpha

chr1_+_129273344 2.675 ENSMUST00000073527.6
ENSMUST00000040311.7
Thsd7b

thrombospondin, type I, domain containing 7B

chr17_+_75178911 2.653 ENSMUST00000112514.1
Ltbp1
latent transforming growth factor beta binding protein 1
chr17_-_48432723 2.651 ENSMUST00000046549.3
Apobec2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2
chrX_-_73659724 2.649 ENSMUST00000114473.1
ENSMUST00000002087.7
Pnck

pregnancy upregulated non-ubiquitously expressed CaM kinase

chr11_+_113619318 2.645 ENSMUST00000146390.2
ENSMUST00000106630.1
Sstr2

somatostatin receptor 2

chr7_+_102101736 2.641 ENSMUST00000033300.2
Art1
ADP-ribosyltransferase 1
chr1_-_119053339 2.625 ENSMUST00000161301.1
ENSMUST00000161451.1
ENSMUST00000162607.1
Gli2


GLI-Kruppel family member GLI2


chr3_-_75270073 2.625 ENSMUST00000039047.4
Serpini2
serine (or cysteine) peptidase inhibitor, clade I, member 2
chr4_-_133872304 2.625 ENSMUST00000157067.2
Rps6ka1
ribosomal protein S6 kinase polypeptide 1
chr1_+_75375271 2.598 ENSMUST00000087122.5
Speg
SPEG complex locus
chr11_+_69965396 2.575 ENSMUST00000018713.6
Cldn7
claudin 7
chr3_+_95588990 2.559 ENSMUST00000177399.1
Golph3l
golgi phosphoprotein 3-like
chr10_+_128909866 2.550 ENSMUST00000026407.7
Cd63
CD63 antigen
chr8_+_36094828 2.512 ENSMUST00000110492.1
D8Ertd82e
DNA segment, Chr 8, ERATO Doi 82, expressed
chr2_+_174760619 2.499 ENSMUST00000029030.2
Edn3
endothelin 3
chr11_-_95514570 2.482 ENSMUST00000058866.7
Nxph3
neurexophilin 3
chr11_+_32205483 2.476 ENSMUST00000121182.1
Snrnp25
small nuclear ribonucleoprotein 25 (U11/U12)
chr1_-_167393826 2.453 ENSMUST00000028005.2
Mgst3
microsomal glutathione S-transferase 3
chr3_+_146404631 2.451 ENSMUST00000106153.2
ENSMUST00000039021.4
ENSMUST00000106151.1
ENSMUST00000149262.1
Ssx2ip



synovial sarcoma, X breakpoint 2 interacting protein



chr2_-_33431324 2.443 ENSMUST00000113158.1
Zbtb34
zinc finger and BTB domain containing 34
chr3_-_68870266 2.417 ENSMUST00000166328.1
Gm17641
predicted gene, 17641
chr6_+_39420378 2.409 ENSMUST00000090237.2
Gm10244
predicted gene 10244
chrX_-_150812715 2.379 ENSMUST00000112697.3
Maged2
melanoma antigen, family D, 2
chr11_+_32205411 2.374 ENSMUST00000039601.3
ENSMUST00000149043.1
Snrnp25

small nuclear ribonucleoprotein 25 (U11/U12)

chr1_+_135836380 2.363 ENSMUST00000178204.1
Tnnt2
troponin T2, cardiac
chr4_-_133967235 2.328 ENSMUST00000123234.1
Hmgn2
high mobility group nucleosomal binding domain 2
chr6_-_39420281 2.325 ENSMUST00000114822.1
ENSMUST00000051671.4
Mkrn1

makorin, ring finger protein, 1

chr1_-_119053619 2.313 ENSMUST00000062483.8
Gli2
GLI-Kruppel family member GLI2
chr8_-_84176552 2.312 ENSMUST00000070102.5
Nanos3
nanos homolog 3 (Drosophila)
chr13_-_56178864 2.306 ENSMUST00000169652.1
Tifab
TRAF-interacting protein with forkhead-associated domain, family member B
chr6_-_39420418 2.269 ENSMUST00000031985.6
Mkrn1
makorin, ring finger protein, 1
chr4_-_43523595 2.251 ENSMUST00000107914.3
Tpm2
tropomyosin 2, beta
chr3_+_146404978 2.229 ENSMUST00000129978.1
Ssx2ip
synovial sarcoma, X breakpoint 2 interacting protein
chr11_-_94474088 2.211 ENSMUST00000107786.1
ENSMUST00000107791.1
ENSMUST00000103166.2
ENSMUST00000107792.1
ENSMUST00000100561.3
ENSMUST00000107793.1
ENSMUST00000107788.1
ENSMUST00000107790.1
ENSMUST00000107789.1
ENSMUST00000107785.1
ENSMUST00000021234.8
Cacna1g










calcium channel, voltage-dependent, T type, alpha 1G subunit










chr5_-_137212389 2.186 ENSMUST00000179412.1
A630081J09Rik
RIKEN cDNA A630081J09 gene
chr13_-_70841790 2.178 ENSMUST00000080145.6
ENSMUST00000109694.2
Adamts16

a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 16

chr3_-_126998408 2.166 ENSMUST00000182764.1
ENSMUST00000044443.8
Ank2

ankyrin 2, brain

chr13_+_23544052 2.162 ENSMUST00000075558.2
Hist1h3f
histone cluster 1, H3f
chr4_-_133967296 2.161 ENSMUST00000105893.1
Hmgn2
high mobility group nucleosomal binding domain 2
chr4_+_133240778 2.136 ENSMUST00000030677.6
Map3k6
mitogen-activated protein kinase kinase kinase 6
chr7_+_30422389 2.131 ENSMUST00000108175.1
Nfkbid
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, delta
chr12_-_32208470 2.127 ENSMUST00000085469.5
Pik3cg
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr3_+_95588928 2.118 ENSMUST00000177390.1
ENSMUST00000098861.4
ENSMUST00000060323.5
Golph3l


golgi phosphoprotein 3-like


chr3_+_152165374 2.106 ENSMUST00000181854.1
D630002J18Rik
RIKEN cDNA D630002J18 gene
chr15_-_77643270 2.106 ENSMUST00000181154.1
ENSMUST00000180949.1
ENSMUST00000181467.1
ENSMUST00000166623.2
Apol11b



apolipoprotein L 11b



chr15_-_96642883 2.105 ENSMUST00000088452.4
Slc38a1
solute carrier family 38, member 1
chrX_-_36989656 2.096 ENSMUST00000060474.7
ENSMUST00000053456.4
ENSMUST00000115239.3
Sept6


septin 6


chr6_+_49367739 2.079 ENSMUST00000060561.8
ENSMUST00000121903.1
ENSMUST00000134786.1
Fam221a


family with sequence similarity 221, member A


chrX_-_57338598 2.071 ENSMUST00000033468.4
ENSMUST00000114736.1
Arhgef6

Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6

chr17_-_78906899 2.061 ENSMUST00000042683.6
ENSMUST00000169544.1
Sult6b1

sulfotransferase family, cytosolic, 6B, member 1

chr6_-_39419967 2.052 ENSMUST00000122996.1
Mkrn1
makorin, ring finger protein, 1
chr7_+_45639964 2.036 ENSMUST00000148532.1
Mamstr
MEF2 activating motif and SAP domain containing transcriptional regulator
chr12_-_32953772 2.022 ENSMUST00000180391.1
ENSMUST00000181670.1
4933406C10Rik

RIKEN cDNA 4933406C10 gene

chr5_-_135251209 2.013 ENSMUST00000062572.2
Fzd9
frizzled homolog 9 (Drosophila)
chr4_-_133968611 2.000 ENSMUST00000102552.1
Hmgn2
high mobility group nucleosomal binding domain 2
chr3_+_95588960 1.995 ENSMUST00000176674.1
ENSMUST00000177389.1
ENSMUST00000176755.1
Golph3l


golgi phosphoprotein 3-like


chr3_+_123446913 1.987 ENSMUST00000029603.8
Prss12
protease, serine, 12 neurotrypsin (motopsin)
chr4_-_156059414 1.980 ENSMUST00000184348.1
Ttll10
tubulin tyrosine ligase-like family, member 10
chr12_+_113014502 1.979 ENSMUST00000084891.4
Pacs2
phosphofurin acidic cluster sorting protein 2
chrX_-_150812932 1.974 ENSMUST00000131241.1
ENSMUST00000147152.1
ENSMUST00000143843.1
Maged2


melanoma antigen, family D, 2


chr13_+_21810428 1.968 ENSMUST00000091745.5
Hist1h2ao
histone cluster 1, H2ao
chr5_-_131538687 1.959 ENSMUST00000161374.1
Auts2
autism susceptibility candidate 2
chr5_+_105415738 1.938 ENSMUST00000112707.1
Lrrc8b
leucine rich repeat containing 8 family, member B
chr4_-_3938354 1.918 ENSMUST00000003369.3
Plag1
pleiomorphic adenoma gene 1
chr12_+_110279228 1.894 ENSMUST00000097228.4
Dio3
deiodinase, iodothyronine type III
chr4_+_140906344 1.887 ENSMUST00000030765.6
Padi2
peptidyl arginine deiminase, type II
chr5_+_34989473 1.881 ENSMUST00000114284.1
ENSMUST00000114285.1
Rgs12

regulator of G-protein signaling 12

chr11_-_70322520 1.880 ENSMUST00000019051.2
Alox12e
arachidonate lipoxygenase, epidermal
chr5_-_73256555 1.863 ENSMUST00000101127.5
ENSMUST00000171179.1
Fryl
Fryl
furry homolog-like (Drosophila)
furry homolog-like (Drosophila)
chr3_+_146404844 1.845 ENSMUST00000106149.1
Ssx2ip
synovial sarcoma, X breakpoint 2 interacting protein
chr8_-_40634750 1.831 ENSMUST00000173957.1
Mtmr7
myotubularin related protein 7
chr5_+_144545883 1.782 ENSMUST00000071782.6
Nptx2
neuronal pentraxin 2
chr9_+_30942541 1.780 ENSMUST00000068135.6
Adamts8
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 8
chr2_-_131187282 1.778 ENSMUST00000028801.1
Spef1
sperm flagellar 1
chr3_-_27153782 1.773 ENSMUST00000175857.1
ENSMUST00000177055.1
ENSMUST00000176535.1
Ect2


ect2 oncogene


chr2_-_27072175 1.756 ENSMUST00000009358.2
Tmem8c
transmembrane protein 8C
chr11_+_96929367 1.750 ENSMUST00000062172.5
Prr15l
proline rich 15-like
chr4_+_119814495 1.747 ENSMUST00000106307.2
Hivep3
human immunodeficiency virus type I enhancer binding protein 3
chr12_-_32208609 1.744 ENSMUST00000053215.7
Pik3cg
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr1_-_166127876 1.728 ENSMUST00000085992.2
Dusp27
dual specificity phosphatase 27 (putative)
chr6_+_118066356 1.715 ENSMUST00000164960.1
Rasgef1a
RasGEF domain family, member 1A
chr5_-_114773488 1.713 ENSMUST00000178440.1
ENSMUST00000043283.7
ENSMUST00000112185.2
Git2


G protein-coupled receptor kinase-interactor 2


chr15_-_101712891 1.701 ENSMUST00000023709.5
Krt5
keratin 5
chr2_+_49787675 1.671 ENSMUST00000028103.6
Lypd6b
LY6/PLAUR domain containing 6B
chr3_-_27153844 1.670 ENSMUST00000176242.2
ENSMUST00000176780.1
Ect2

ect2 oncogene

chr3_-_27153861 1.661 ENSMUST00000108300.1
ENSMUST00000108298.2
Ect2

ect2 oncogene

chr6_-_53068562 1.648 ENSMUST00000074541.5
Jazf1
JAZF zinc finger 1
chr15_+_77477044 1.648 ENSMUST00000060551.2
ENSMUST00000119997.1
Apol10a

apolipoprotein L 10A

chr6_+_112459501 1.642 ENSMUST00000075477.6
Cav3
caveolin 3
chr17_-_72603709 1.638 ENSMUST00000086639.4
Alk
anaplastic lymphoma kinase
chr6_-_87496279 1.627 ENSMUST00000101197.2
Arhgap25
Rho GTPase activating protein 25
chr19_+_53529100 1.617 ENSMUST00000038287.6
Dusp5
dual specificity phosphatase 5
chr15_-_78773452 1.613 ENSMUST00000018313.5
Mfng
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr4_+_130915949 1.611 ENSMUST00000030316.6
Laptm5
lysosomal-associated protein transmembrane 5
chr17_+_28142267 1.606 ENSMUST00000043503.3
Scube3
signal peptide, CUB domain, EGF-like 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 7.9 GO:0046882 negative regulation of follicle-stimulating hormone secretion(GO:0046882)
1.5 11.8 GO:0007144 female meiosis I(GO:0007144)
1.3 4.0 GO:0036018 response to erythropoietin(GO:0036017) cellular response to erythropoietin(GO:0036018) erythropoietin-mediated signaling pathway(GO:0038162)
1.3 4.0 GO:0002017 regulation of blood volume by renal aldosterone(GO:0002017)
1.3 3.9 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
1.2 4.9 GO:0060032 notochord regression(GO:0060032)
1.2 6.1 GO:0006564 L-serine biosynthetic process(GO:0006564)
1.2 3.5 GO:0071314 cellular response to cocaine(GO:0071314)
1.1 48.6 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
1.1 3.3 GO:0014064 positive regulation of serotonin secretion(GO:0014064)
1.0 4.0 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
1.0 3.0 GO:0048389 intermediate mesoderm development(GO:0048389) pattern specification involved in mesonephros development(GO:0061227) anterior/posterior pattern specification involved in kidney development(GO:0072098) kidney smooth muscle tissue development(GO:0072194)
1.0 3.8 GO:0061743 motor learning(GO:0061743)
0.9 4.4 GO:0010956 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) regulation of interleukin-6-mediated signaling pathway(GO:0070103)
0.9 2.6 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.8 3.2 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.8 7.2 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.8 2.4 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.8 3.8 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.7 7.5 GO:0090527 actin filament reorganization(GO:0090527)
0.7 10.2 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.7 6.6 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.7 2.2 GO:0003345 proepicardium cell migration involved in pericardium morphogenesis(GO:0003345)
0.7 1.4 GO:0035582 sequestering of BMP in extracellular matrix(GO:0035582)
0.7 4.1 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.7 4.1 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.7 4.1 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100) vein smooth muscle contraction(GO:0014826)
0.7 2.0 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.7 2.0 GO:1990523 bone regeneration(GO:1990523)
0.7 2.0 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.6 1.9 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.6 1.2 GO:0002554 serotonin secretion by platelet(GO:0002554)
0.6 2.3 GO:0007356 thorax and anterior abdomen determination(GO:0007356)
0.6 3.9 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
0.6 5.5 GO:0060923 cardiac muscle cell fate commitment(GO:0060923)
0.6 2.2 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.5 1.6 GO:0035995 detection of muscle stretch(GO:0035995)
0.5 1.6 GO:0036269 swimming behavior(GO:0036269)
0.5 4.9 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.5 4.4 GO:0070294 renal sodium ion absorption(GO:0070294)
0.5 2.6 GO:0038169 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.5 15.1 GO:0045780 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.5 2.6 GO:2000680 regulation of rubidium ion transport(GO:2000680)
0.5 1.5 GO:0051466 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) positive regulation of corticotropin-releasing hormone secretion(GO:0051466) regulation of G-protein coupled receptor internalization(GO:1904020)
0.5 3.0 GO:0036376 sodium ion export from cell(GO:0036376)
0.5 5.9 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.5 3.8 GO:0048539 bone marrow development(GO:0048539)
0.5 1.4 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.4 2.7 GO:0006216 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.4 1.3 GO:0072061 inner medullary collecting duct development(GO:0072061)
0.4 3.4 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.4 1.2 GO:0051385 response to mineralocorticoid(GO:0051385)
0.4 1.6 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.4 1.2 GO:0046077 dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate metabolic process(GO:0009138) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077)
0.4 1.2 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.4 1.5 GO:1902303 negative regulation of potassium ion export(GO:1902303)
0.4 1.9 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.4 1.9 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.4 6.0 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.4 1.1 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.4 6.5 GO:0046514 ceramide catabolic process(GO:0046514)
0.4 1.1 GO:0010615 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.4 7.6 GO:1900153 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.4 1.4 GO:0033580 protein glycosylation at cell surface(GO:0033575) protein galactosylation at cell surface(GO:0033580) protein galactosylation(GO:0042125)
0.4 2.1 GO:0006868 glutamine transport(GO:0006868)
0.3 1.0 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.3 0.7 GO:0050917 sensory perception of umami taste(GO:0050917)
0.3 3.0 GO:0120009 intermembrane lipid transfer(GO:0120009)
0.3 1.3 GO:0050960 detection of temperature stimulus involved in thermoception(GO:0050960) regulation of establishment of blood-brain barrier(GO:0090210) negative regulation of establishment of blood-brain barrier(GO:0090212) response to capsazepine(GO:1901594)
0.3 2.0 GO:0018094 protein polyglycylation(GO:0018094)
0.3 4.3 GO:0048733 sebaceous gland development(GO:0048733)
0.3 1.3 GO:0048022 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.3 1.3 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.3 0.9 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.3 8.8 GO:0046685 response to arsenic-containing substance(GO:0046685)
0.3 2.7 GO:0099004 calmodulin dependent kinase signaling pathway(GO:0099004)
0.3 3.3 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.3 2.9 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.3 0.9 GO:0071288 cellular response to mercury ion(GO:0071288) cellular response to water stimulus(GO:0071462)
0.3 5.1 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.3 0.8 GO:2000556 regulation of T-helper 1 cell cytokine production(GO:2000554) positive regulation of T-helper 1 cell cytokine production(GO:2000556)
0.3 1.1 GO:0010719 negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.3 1.6 GO:0002317 plasma cell differentiation(GO:0002317)
0.3 0.5 GO:0072034 renal vesicle induction(GO:0072034)
0.2 1.0 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.2 3.6 GO:0030322 stabilization of membrane potential(GO:0030322)
0.2 2.1 GO:0033085 negative regulation of T cell differentiation in thymus(GO:0033085)
0.2 0.7 GO:0033082 regulation of extrathymic T cell differentiation(GO:0033082)
0.2 1.2 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.2 0.7 GO:0003032 detection of oxygen(GO:0003032)
0.2 8.1 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.2 0.9 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.2 9.8 GO:0003009 skeletal muscle contraction(GO:0003009)
0.2 6.5 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.2 0.6 GO:0002874 positive regulation of chronic inflammatory response(GO:0002678) regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.2 0.6 GO:0006713 glucocorticoid catabolic process(GO:0006713)
0.2 0.6 GO:0006601 creatine biosynthetic process(GO:0006601)
0.2 2.8 GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.2 5.2 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.2 5.7 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.2 3.3 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.2 0.6 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.2 0.8 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.2 1.9 GO:0019336 phenol-containing compound catabolic process(GO:0019336)
0.2 5.3 GO:0030903 notochord development(GO:0030903)
0.2 1.9 GO:0019372 lipoxygenase pathway(GO:0019372)
0.2 0.6 GO:0060167 germinal center B cell differentiation(GO:0002314) adenosine catabolic process(GO:0006154) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) purine nucleobase salvage(GO:0043096) hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101) purine deoxyribonucleoside metabolic process(GO:0046122) regulation of adenosine receptor signaling pathway(GO:0060167) negative regulation of mucus secretion(GO:0070256)
0.2 3.9 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.2 1.3 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.2 0.3 GO:0099541 trans-synaptic signaling by lipid(GO:0099541) trans-synaptic signaling by endocannabinoid(GO:0099542)
0.2 1.5 GO:0007256 activation of JNKK activity(GO:0007256)
0.2 0.5 GO:1901675 response to methylglyoxal(GO:0051595) negative regulation of histone H3-K27 acetylation(GO:1901675)
0.2 0.3 GO:0072236 metanephric loop of Henle development(GO:0072236)
0.2 6.3 GO:0048194 Golgi vesicle budding(GO:0048194)
0.2 0.5 GO:0014009 glial cell proliferation(GO:0014009)
0.2 0.5 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.1 0.4 GO:1903490 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.1 1.2 GO:0014848 urinary bladder smooth muscle contraction(GO:0014832) urinary tract smooth muscle contraction(GO:0014848)
0.1 2.6 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.1 0.4 GO:0045819 plasmacytoid dendritic cell activation(GO:0002270) positive regulation of glycogen catabolic process(GO:0045819)
0.1 2.0 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.1 0.4 GO:0043974 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
0.1 3.3 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.1 0.8 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.1 1.5 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.1 18.1 GO:0007586 digestion(GO:0007586)
0.1 0.7 GO:0098909 regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.1 0.5 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.1 1.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.6 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.1 3.8 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 1.0 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.1 0.8 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.1 1.6 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.9 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.1 0.5 GO:0090666 telomere assembly(GO:0032202) scaRNA localization to Cajal body(GO:0090666)
0.1 0.6 GO:0061577 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577)
0.1 1.6 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.1 1.3 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804)
0.1 1.4 GO:0060033 anatomical structure regression(GO:0060033)
0.1 1.1 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.1 0.5 GO:0002121 inter-male aggressive behavior(GO:0002121)
0.1 1.7 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 0.4 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.1 0.5 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) negative regulation of serotonin uptake(GO:0051612)
0.1 1.0 GO:0035608 protein deglutamylation(GO:0035608)
0.1 2.3 GO:0045109 intermediate filament organization(GO:0045109)
0.1 0.6 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 0.6 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.1 0.3 GO:0014827 intestine smooth muscle contraction(GO:0014827)
0.1 0.6 GO:0060666 pulmonary myocardium development(GO:0003350) dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 1.6 GO:0060539 diaphragm development(GO:0060539)
0.1 0.7 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.1 0.2 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.1 0.9 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 4.3 GO:0000186 activation of MAPKK activity(GO:0000186)
0.1 0.7 GO:0097369 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719)
0.1 1.5 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1 0.4 GO:0098964 dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964)
0.1 0.6 GO:0014850 response to muscle activity(GO:0014850)
0.1 2.6 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.1 2.8 GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032435)
0.1 0.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 1.1 GO:0048286 lung alveolus development(GO:0048286)
0.1 1.0 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.1 0.4 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.1 1.4 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.1 0.4 GO:0014842 skeletal muscle satellite cell proliferation(GO:0014841) regulation of skeletal muscle satellite cell proliferation(GO:0014842) skeletal muscle cell proliferation(GO:0014856) regulation of skeletal muscle cell proliferation(GO:0014857)
0.1 0.7 GO:2000194 regulation of female gonad development(GO:2000194)
0.1 0.5 GO:0060017 parathyroid gland development(GO:0060017)
0.1 1.4 GO:0043496 regulation of protein homodimerization activity(GO:0043496)
0.1 0.3 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.1 1.0 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.1 1.3 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.1 0.2 GO:0072162 metanephric mesenchymal cell differentiation(GO:0072162)
0.0 3.0 GO:0065002 intracellular protein transmembrane transport(GO:0065002)
0.0 0.1 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.1 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.0 0.4 GO:0071600 otic vesicle morphogenesis(GO:0071600)
0.0 0.9 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.0 0.3 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0 0.6 GO:0071549 response to dexamethasone(GO:0071548) cellular response to dexamethasone stimulus(GO:0071549)
0.0 0.7 GO:0060065 uterus development(GO:0060065)
0.0 0.5 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.4 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.5 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 4.0 GO:0042100 B cell proliferation(GO:0042100)
0.0 0.3 GO:2000121 regulation of removal of superoxide radicals(GO:2000121)
0.0 1.5 GO:0000154 rRNA modification(GO:0000154)
0.0 1.1 GO:0032288 myelin assembly(GO:0032288)
0.0 0.9 GO:1903830 magnesium ion transport(GO:0015693) magnesium ion transmembrane transport(GO:1903830)
0.0 0.3 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.8 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.2 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.4 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465)
0.0 0.3 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.3 GO:0043201 response to leucine(GO:0043201) cellular response to leucine(GO:0071233)
0.0 1.0 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.4 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.0 0.7 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.0 0.1 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 3.6 GO:0006342 chromatin silencing(GO:0006342)
0.0 0.4 GO:0060742 epithelial cell differentiation involved in prostate gland development(GO:0060742)
0.0 0.1 GO:1903999 regulation of eating behavior(GO:1903998) negative regulation of eating behavior(GO:1903999)
0.0 0.1 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 1.2 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.1 GO:0002159 desmosome assembly(GO:0002159)
0.0 4.2 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 0.1 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089) cellular response to actinomycin D(GO:0072717)
0.0 1.0 GO:0048747 muscle fiber development(GO:0048747)
0.0 0.7 GO:0048266 behavioral response to pain(GO:0048266)
0.0 3.0 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 1.7 GO:0045444 fat cell differentiation(GO:0045444)
0.0 0.7 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 1.7 GO:1902017 regulation of cilium assembly(GO:1902017)
0.0 0.5 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 0.4 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.7 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 0.1 GO:0042637 catagen(GO:0042637)
0.0 0.1 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.8 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.4 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.6 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.2 GO:0043271 negative regulation of ion transport(GO:0043271)
0.0 2.9 GO:0006936 muscle contraction(GO:0006936)
0.0 0.7 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.1 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.0 0.7 GO:0033045 regulation of sister chromatid segregation(GO:0033045)
0.0 1.4 GO:0044070 regulation of anion transport(GO:0044070)
0.0 0.0 GO:0061009 common bile duct development(GO:0061009)
0.0 3.0 GO:0072659 protein localization to plasma membrane(GO:0072659)
0.0 0.4 GO:0060706 cell differentiation involved in embryonic placenta development(GO:0060706)
0.0 0.6 GO:0000266 mitochondrial fission(GO:0000266)
0.0 4.0 GO:0008380 RNA splicing(GO:0008380)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 7.9 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
2.1 48.0 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
1.9 5.7 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
1.4 4.3 GO:0071149 TEAD-2-YAP complex(GO:0071149)
1.0 5.1 GO:0097149 centralspindlin complex(GO:0097149)
1.0 3.9 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
1.0 17.3 GO:0005861 troponin complex(GO:0005861)
0.8 0.8 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.7 3.0 GO:0014802 terminal cisterna(GO:0014802)
0.7 2.1 GO:0005940 septin ring(GO:0005940)
0.7 6.2 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.7 8.5 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.6 2.6 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.6 6.8 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.5 2.7 GO:0099524 region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524)
0.5 1.5 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.5 4.5 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.4 1.2 GO:0030934 collagen type XII trimer(GO:0005595) anchoring collagen complex(GO:0030934)
0.4 1.1 GO:0005955 calcineurin complex(GO:0005955)
0.4 4.9 GO:0097542 ciliary tip(GO:0097542)
0.3 19.2 GO:0031672 A band(GO:0031672)
0.3 3.1 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.2 1.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.2 1.5 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.2 0.6 GO:0005607 laminin-2 complex(GO:0005607)
0.2 3.5 GO:0005767 secondary lysosome(GO:0005767)
0.2 5.9 GO:0042588 zymogen granule(GO:0042588)
0.2 3.5 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.2 6.1 GO:0034451 centriolar satellite(GO:0034451)
0.2 0.8 GO:0044302 dentate gyrus mossy fiber(GO:0044302)
0.2 2.0 GO:0043083 synaptic cleft(GO:0043083)
0.2 3.9 GO:0099634 postsynaptic specialization membrane(GO:0099634)
0.2 7.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.2 1.0 GO:0005663 DNA replication factor C complex(GO:0005663)
0.2 0.7 GO:1990357 terminal web(GO:1990357)
0.2 4.8 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.1 2.0 GO:0098936 intrinsic component of postsynaptic membrane(GO:0098936) integral component of postsynaptic membrane(GO:0099055) intrinsic component of synaptic membrane(GO:0099240) integral component of synaptic membrane(GO:0099699)
0.1 0.9 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.1 0.5 GO:0097512 cardiac myofibril(GO:0097512)
0.1 1.0 GO:0001940 male pronucleus(GO:0001940)
0.1 1.5 GO:0044294 dendritic growth cone(GO:0044294)
0.1 7.7 GO:0014704 intercalated disc(GO:0014704)
0.1 2.2 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 2.0 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 1.4 GO:0001527 microfibril(GO:0001527)
0.1 7.5 GO:0031985 Golgi cisterna(GO:0031985)
0.1 4.6 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 4.1 GO:0097440 apical dendrite(GO:0097440)
0.1 1.9 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 0.5 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.1 0.3 GO:0071953 elastic fiber(GO:0071953)
0.1 1.1 GO:0036501 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) UFD1-NPL4 complex(GO:0036501)
0.1 3.5 GO:0030315 T-tubule(GO:0030315)
0.1 4.8 GO:0043209 myelin sheath(GO:0043209)
0.1 2.1 GO:0005795 Golgi stack(GO:0005795)
0.1 0.9 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 0.4 GO:0034709 methylosome(GO:0034709)
0.1 9.1 GO:0000922 spindle pole(GO:0000922)
0.1 4.7 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 8.9 GO:0005819 spindle(GO:0005819)
0.1 1.0 GO:0016460 myosin II complex(GO:0016460)
0.1 0.3 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 1.0 GO:0031527 filopodium membrane(GO:0031527)
0.1 6.3 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.4 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.3 GO:0043196 varicosity(GO:0043196)
0.0 0.4 GO:0061574 ASAP complex(GO:0061574)
0.0 2.3 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 2.5 GO:0030018 Z disc(GO:0030018)
0.0 1.0 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 1.2 GO:0001533 cornified envelope(GO:0001533)
0.0 3.6 GO:0016605 PML body(GO:0016605)
0.0 7.5 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 1.1 GO:0031941 filamentous actin(GO:0031941)
0.0 2.1 GO:0042629 mast cell granule(GO:0042629)
0.0 6.2 GO:0030427 site of polarized growth(GO:0030427)
0.0 3.7 GO:0000932 P-body(GO:0000932)
0.0 3.0 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.3 GO:0016235 aggresome(GO:0016235)
0.0 1.2 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 1.2 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.5 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 2.5 GO:0005604 basement membrane(GO:0005604)
0.0 0.9 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.2 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 2.0 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.0 0.5 GO:0032590 dendrite membrane(GO:0032590)
0.0 1.5 GO:0005930 axoneme(GO:0005930)
0.0 7.5 GO:0016607 nuclear speck(GO:0016607)
0.0 0.3 GO:0043218 compact myelin(GO:0043218)
0.0 2.0 GO:0031514 motile cilium(GO:0031514)
0.0 0.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 4.9 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.7 GO:0005875 microtubule associated complex(GO:0005875)
0.0 1.2 GO:0030027 lamellipodium(GO:0030027)
0.0 0.1 GO:0005883 neurofilament(GO:0005883)
0.0 0.5 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.3 GO:0001891 phagocytic cup(GO:0001891)
0.0 3.2 GO:0005929 cilium(GO:0005929) intraciliary transport particle(GO:0030990)
0.0 0.4 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.6 GO:0042383 sarcolemma(GO:0042383)
0.0 2.4 GO:0099572 postsynaptic specialization(GO:0099572)
0.0 0.7 GO:0000786 nucleosome(GO:0000786)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.3 43.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
2.0 5.9 GO:0004771 sterol esterase activity(GO:0004771) retinyl-palmitate esterase activity(GO:0050253)
1.6 12.6 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
1.3 4.0 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
1.2 6.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
1.2 12.0 GO:0031014 troponin T binding(GO:0031014)
1.2 3.5 GO:0043404 corticotropin-releasing hormone receptor activity(GO:0043404) corticotropin-releasing hormone binding(GO:0051424)
1.1 3.3 GO:0005330 dopamine:sodium symporter activity(GO:0005330)
1.0 4.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.7 6.6 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.7 6.5 GO:0034711 inhibin binding(GO:0034711)
0.7 4.1 GO:0035184 histone threonine kinase activity(GO:0035184)
0.7 2.0 GO:0070737 protein-glycine ligase activity, elongating(GO:0070737)
0.6 1.9 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.6 3.0 GO:0005308 creatine transmembrane transporter activity(GO:0005308)
0.6 2.4 GO:0030172 troponin C binding(GO:0030172)
0.6 1.7 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.5 1.6 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.5 1.6 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.5 1.6 GO:0048030 disaccharide binding(GO:0048030)
0.5 2.6 GO:0004994 somatostatin receptor activity(GO:0004994)
0.5 15.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.5 1.9 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.5 2.8 GO:0004111 creatine kinase activity(GO:0004111)
0.4 6.2 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.4 2.7 GO:0004126 cytidine deaminase activity(GO:0004126)
0.4 4.4 GO:0004498 calcidiol 1-monooxygenase activity(GO:0004498)
0.4 8.8 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.4 1.7 GO:0050436 microfibril binding(GO:0050436)
0.4 2.1 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.4 4.0 GO:0043559 insulin binding(GO:0043559)
0.4 1.2 GO:0009041 uridylate kinase activity(GO:0009041)
0.4 1.9 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.4 3.3 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.4 3.9 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.3 1.0 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.3 3.0 GO:0120013 intermembrane lipid transfer activity(GO:0120013)
0.3 1.3 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
0.3 6.0 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.3 5.2 GO:0043495 protein membrane anchor(GO:0043495)
0.3 1.2 GO:0019767 IgE receptor activity(GO:0019767)
0.3 11.0 GO:0008307 structural constituent of muscle(GO:0008307)
0.3 2.7 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.3 1.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.3 1.3 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.3 2.6 GO:0008046 axon guidance receptor activity(GO:0008046)
0.3 1.5 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.2 1.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.2 1.7 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.2 1.4 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.2 1.2 GO:0038100 nodal binding(GO:0038100)
0.2 4.4 GO:0004180 carboxypeptidase activity(GO:0004180)
0.2 3.6 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.2 0.9 GO:0052743 inositol tetrakisphosphate phosphatase activity(GO:0052743)
0.2 1.1 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.2 1.3 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.2 0.9 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.2 5.4 GO:0030506 ankyrin binding(GO:0030506)
0.2 1.0 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.2 1.2 GO:0045340 mercury ion binding(GO:0045340)
0.2 6.7 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.2 4.3 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.2 2.6 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.2 0.9 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.2 1.3 GO:0000150 recombinase activity(GO:0000150)
0.2 0.9 GO:1904288 BAT3 complex binding(GO:1904288)
0.2 10.2 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.2 1.7 GO:0031005 filamin binding(GO:0031005)
0.2 0.7 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.2 1.5 GO:0033691 sialic acid binding(GO:0033691)
0.2 1.0 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.2 1.1 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 3.5 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 0.7 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.1 2.2 GO:0045499 chemorepellent activity(GO:0045499)
0.1 1.2 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.1 0.6 GO:0070052 collagen V binding(GO:0070052)
0.1 1.0 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 0.4 GO:0000402 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
0.1 1.4 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 1.9 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 5.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 7.2 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 1.1 GO:0070097 delta-catenin binding(GO:0070097)
0.1 0.9 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.1 1.9 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 0.9 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1 16.8 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.1 2.7 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 1.2 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.1 1.2 GO:0070700 BMP receptor binding(GO:0070700)
0.1 1.3 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 1.7 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.1 0.4 GO:0034190 apolipoprotein receptor binding(GO:0034190)
0.1 4.3 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.7 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 4.3 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 0.4 GO:2001069 glycogen binding(GO:2001069)
0.1 1.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 1.0 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 0.4 GO:0051425 PTB domain binding(GO:0051425)
0.1 0.5 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.1 0.6 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 0.8 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1 30.5 GO:0008236 serine-type peptidase activity(GO:0008236)
0.1 2.5 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 2.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 1.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907) G-protein coupled neurotransmitter receptor activity(GO:0099528)
0.1 2.0 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 5.4 GO:0015459 potassium channel regulator activity(GO:0015459)
0.1 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.6 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 0.7 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 4.8 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 0.2 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
0.1 0.8 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.4 GO:0045322 unmethylated CpG binding(GO:0045322)
0.1 0.3 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.1 0.9 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 2.5 GO:0005109 frizzled binding(GO:0005109)
0.1 0.4 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.1 0.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 1.5 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 1.2 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.1 1.2 GO:0043422 protein kinase B binding(GO:0043422)
0.0 1.9 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.4 GO:0008527 taste receptor activity(GO:0008527)
0.0 1.6 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.0 0.5 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.5 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.9 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.4 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.9 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 1.0 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.8 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.6 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.7 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.0 GO:0051022 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.3 GO:0001849 complement component C1q binding(GO:0001849)
0.0 1.4 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.4 GO:0045182 translation regulator activity(GO:0045182)
0.0 3.5 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.6 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 4.3 GO:0001076 transcription factor activity, RNA polymerase II transcription factor binding(GO:0001076)
0.0 0.5 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 0.1 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.1 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.0 1.2 GO:0050699 WW domain binding(GO:0050699)
0.0 8.5 GO:0005096 GTPase activator activity(GO:0005096)
0.0 1.1 GO:0030414 peptidase inhibitor activity(GO:0030414)
0.0 1.8 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.7 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.5 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.4 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.2 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.8 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.3 GO:0098988 G-protein coupled glutamate receptor activity(GO:0098988)
0.0 0.4 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.7 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.7 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.7 GO:0030291 protein serine/threonine kinase inhibitor activity(GO:0030291)
0.0 3.5 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.5 GO:0001784 phosphotyrosine residue binding(GO:0001784)
0.0 2.6 GO:0005125 cytokine activity(GO:0005125)
0.0 5.7 GO:0005525 GTP binding(GO:0005525)
0.0 2.7 GO:0003729 mRNA binding(GO:0003729)
0.0 0.3 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.1 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.6 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 1.5 GO:0061660 Atg12 activating enzyme activity(GO:0019778) Atg8-specific protease activity(GO:0019786) Atg12 conjugating enzyme activity(GO:0061651) Atg12 ligase activity(GO:0061660)
0.0 0.2 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.1 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 11.8 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.6 12.3 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.3 8.2 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.3 9.2 SA_B_CELL_RECEPTOR_COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.2 1.1 PID_A6B1_A6B4_INTEGRIN_PATHWAY a6b1 and a6b4 Integrin signaling
0.2 14.7 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.2 6.0 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.2 4.6 PID_PI3K_PLC_TRK_PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.2 10.3 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.2 3.2 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.1 3.9 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.1 3.9 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.1 3.5 PID_EPO_PATHWAY EPO signaling pathway
0.1 4.6 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.1 3.8 PID_AMB2_NEUTROPHILS_PATHWAY amb2 Integrin signaling
0.1 20.9 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 6.0 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.1 1.4 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 1.0 PID_TNF_PATHWAY TNF receptor signaling pathway
0.1 3.5 PID_RAC1_PATHWAY RAC1 signaling pathway
0.1 0.4 SA_FAS_SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 2.7 PID_ENDOTHELIN_PATHWAY Endothelins
0.1 1.6 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.1 0.5 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 2.5 PID_ERBB4_PATHWAY ErbB4 signaling events
0.1 0.6 ST_JAK_STAT_PATHWAY Jak-STAT Pathway
0.0 1.2 PID_INTEGRIN3_PATHWAY Beta3 integrin cell surface interactions
0.0 2.2 PID_FCER1_PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 1.4 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.0 2.2 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.0 0.9 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.0 0.8 PID_REELIN_PATHWAY Reelin signaling pathway
0.0 1.5 PID_ATR_PATHWAY ATR signaling pathway
0.0 1.0 PID_CONE_PATHWAY Visual signal transduction: Cones
0.0 0.7 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.6 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.0 0.4 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.0 1.2 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.4 PID_AP1_PATHWAY AP-1 transcription factor network
0.0 0.6 PID_ATF2_PATHWAY ATF-2 transcription factor network
0.0 1.7 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 1.0 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.3 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.0 3.1 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.8 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.0 0.9 PID_MTOR_4PATHWAY mTOR signaling pathway
0.0 0.5 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 48.9 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.7 6.6 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.7 11.8 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.6 30.7 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.4 8.0 REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.4 15.1 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.2 2.6 REACTOME_DEFENSINS Genes involved in Defensins
0.2 6.1 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.2 6.5 REACTOME_ERK_MAPK_TARGETS Genes involved in ERK/MAPK targets
0.2 4.1 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 2.8 REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS Genes involved in Trafficking of AMPA receptors
0.1 1.2 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 1.9 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.1 3.3 REACTOME_BASIGIN_INTERACTIONS Genes involved in Basigin interactions
0.1 5.7 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.1 2.5 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 4.2 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 3.3 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.1 3.3 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 1.6 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 1.3 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 2.0 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.1 3.1 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 1.3 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
0.1 2.5 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.1 0.7 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.1 5.8 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 1.4 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.0 9.2 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.5 REACTOME_REGULATION_OF_SIGNALING_BY_CBL Genes involved in Regulation of signaling by CBL
0.0 0.7 REACTOME_PLATELET_CALCIUM_HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 1.2 REACTOME_TRAF6_MEDIATED_NFKB_ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 1.6 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 6.1 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 1.6 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 1.3 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 1.0 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 0.7 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.6 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.0 1.0 REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS Genes involved in Activation of ATR in response to replication stress
0.0 1.3 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.3 REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS Genes involved in G alpha (z) signalling events
0.0 0.7 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.0 0.5 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 1.5 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.5 REACTOME_ELONGATION_ARREST_AND_RECOVERY Genes involved in Elongation arrest and recovery
0.0 1.2 REACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.0 1.1 REACTOME_G_ALPHA_S_SIGNALLING_EVENTS Genes involved in G alpha (s) signalling events
0.0 1.3 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.4 REACTOME_NEP_NS2_INTERACTS_WITH_THE_CELLULAR_EXPORT_MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.2 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins