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GSE58827: Dynamics of the Mouse Liver

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Results for Tcf3

Z-value: 1.37

Motif logo

Transcription factors associated with Tcf3

Gene Symbol Gene ID Gene Info
ENSMUSG00000020167.8 transcription factor 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tcf3mm10_v2_chr10_-_80433615_804336550.853.4e-11Click!

Activity profile of Tcf3 motif

Sorted Z-values of Tcf3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr8_+_23139064 19.58 ENSMUST00000033947.8
ankyrin 1, erythroid
chr8_+_23139030 18.24 ENSMUST00000121075.1
ankyrin 1, erythroid
chr12_+_109459843 15.11 ENSMUST00000173812.1
delta-like 1 homolog (Drosophila)
chr2_+_131186942 11.80 ENSMUST00000028804.8
ENSMUST00000079857.8
cell division cycle 25B
chr11_-_102365111 8.80 ENSMUST00000006749.9
solute carrier family 4 (anion exchanger), member 1
chr6_+_30639218 8.76 ENSMUST00000031806.9
carboxypeptidase A1, pancreatic
chr6_-_41377604 8.56 ENSMUST00000096003.5
protease, serine, 3
chr7_-_17056669 8.42 ENSMUST00000037762.4
hypoxia inducible factor 3, alpha subunit
chr2_-_170406501 7.95 ENSMUST00000154650.1
breast carcinoma amplified sequence 1
chr1_+_75507077 7.95 ENSMUST00000037330.4
inhibin alpha
chr11_+_115900125 7.70 ENSMUST00000142089.1
ENSMUST00000131566.1
small integral membrane protein 5
chr11_+_115899943 7.65 ENSMUST00000152171.1
small integral membrane protein 5
chr2_+_153492790 7.23 ENSMUST00000109783.1
RIKEN cDNA 4930404H24 gene
chr6_+_41458923 7.10 ENSMUST00000031910.7
protease, serine, 1 (trypsin 1)
chr11_-_120648104 7.05 ENSMUST00000026134.2
myeloid-associated differentiation marker-like 2
chr11_-_53480178 7.02 ENSMUST00000104955.2
sosondowah ankyrin repeat domain family member A
chr17_-_26201328 6.80 ENSMUST00000025019.2
Rho GDP dissociation inhibitor (GDI) gamma
chr6_+_29694204 6.79 ENSMUST00000046750.7
ENSMUST00000115250.3
tetraspanin 33
chr2_+_84734050 6.74 ENSMUST00000090729.2
yippee-like 4 (Drosophila)
chr10_-_19851459 6.57 ENSMUST00000059805.4
solute carrier family 35, member D3
chr3_-_152166230 6.36 ENSMUST00000046614.9
GIPC PDZ domain containing family, member 2
chr19_-_15924560 6.15 ENSMUST00000162053.1
phosphoserine aminotransferase 1
chr6_+_41392356 6.12 ENSMUST00000049079.7
predicted gene 5771
chr1_-_75506331 5.98 ENSMUST00000113567.2
ENSMUST00000113565.2
obscurin-like 1
chr2_-_28563362 5.94 ENSMUST00000028161.5
carboxyl ester lipase
chr17_-_87797994 5.87 ENSMUST00000055221.7
potassium channel, subfamily K, member 12
chr6_-_41314700 5.76 ENSMUST00000064324.5
trypsin 5
chr17_-_26201363 5.76 ENSMUST00000121959.1
Rho GDP dissociation inhibitor (GDI) gamma
chr3_-_20275659 5.71 ENSMUST00000011607.5
carboxypeptidase B1 (tissue)
chr16_+_87553313 5.69 ENSMUST00000026700.7
Map3k7 C-terminal like
chr17_-_43502773 5.65 ENSMUST00000024707.8
ENSMUST00000117137.1
meprin 1 alpha
chr9_-_39604124 5.53 ENSMUST00000042485.4
ENSMUST00000141370.1
expressed sequence AW551984
chr8_+_23139157 5.41 ENSMUST00000174435.1
ankyrin 1, erythroid
chr12_-_76709997 5.37 ENSMUST00000166101.1
spectrin beta, erythrocytic
chr8_+_3665747 5.31 ENSMUST00000014118.2
RIKEN cDNA 1810033B17 gene
chr11_+_53519871 5.25 ENSMUST00000120878.2
septin 8
chr5_+_123076275 5.24 ENSMUST00000067505.8
ENSMUST00000111619.3
ENSMUST00000160344.1
transmembrane protein 120B
chr2_+_91035613 5.20 ENSMUST00000111445.3
ENSMUST00000111446.3
ENSMUST00000050323.5
receptor-associated protein of the synapse
chr14_+_70457447 5.13 ENSMUST00000003561.3
phytanoyl-CoA hydroxylase interacting protein
chr17_-_35027909 5.05 ENSMUST00000040151.2
suppressor APC domain containing 1
chr11_+_53519920 4.96 ENSMUST00000147912.1
septin 8
chr8_-_105933832 4.95 ENSMUST00000034368.6
chymotrypsin-like
chr6_+_40964760 4.91 ENSMUST00000076638.5
RIKEN cDNA 1810009J06 gene
chr13_-_55528511 4.88 ENSMUST00000047877.4
docking protein 3
chr5_-_73191848 4.82 ENSMUST00000176910.1
furry homolog-like (Drosophila)
chr8_+_94977101 4.74 ENSMUST00000179619.1
G protein-coupled receptor 56
chr11_+_61956779 4.58 ENSMUST00000049836.7
sperm antigen with calponin homology and coiled-coil domains 1
chr4_-_133872997 4.56 ENSMUST00000137486.2
ribosomal protein S6 kinase polypeptide 1
chr3_-_100489324 4.52 ENSMUST00000061455.8
family with sequence similarity 46, member C
chr5_-_107726017 4.40 ENSMUST00000159263.2
growth factor independent 1
chr19_+_6105774 4.39 ENSMUST00000044451.3
N-acetylated alpha-linked acidic dipeptidase-like 1
chr7_+_142441808 4.38 ENSMUST00000105971.1
ENSMUST00000145287.1
troponin I, skeletal, fast 2
chr7_+_45216671 4.29 ENSMUST00000134420.1
TEA domain family member 2
chr1_+_74791516 4.28 ENSMUST00000006718.8
wingless related MMTV integration site 10a
chr2_+_103969528 4.27 ENSMUST00000123437.1
ENSMUST00000163256.1
LIM domain only 2
chr1_+_135132693 4.14 ENSMUST00000049449.4
protein tyrosine phosphatase, non-receptor type 7
chr7_+_122289297 4.12 ENSMUST00000064989.5
ENSMUST00000064921.4
protein kinase C, beta
chr18_+_34840575 4.11 ENSMUST00000043484.7
receptor accessory protein 2
chr19_+_60755947 4.07 ENSMUST00000088237.4
nanos homolog 1 (Drosophila)
chr11_-_107716517 4.06 ENSMUST00000021065.5
calcium channel, voltage-dependent, gamma subunit 1
chr9_-_21963568 4.04 ENSMUST00000006397.5
erythropoietin receptor
chr8_+_71597648 4.04 ENSMUST00000143662.1
family with sequence similarity 129, member C
chr7_+_67952817 4.02 ENSMUST00000005671.8
insulin-like growth factor I receptor
chr8_+_105518736 4.02 ENSMUST00000034363.5
hydroxysteroid 11-beta dehydrogenase 2
chr16_-_16869255 4.02 ENSMUST00000075017.4
pre-B lymphocyte gene 1
chr1_+_135133272 3.99 ENSMUST00000167080.1
protein tyrosine phosphatase, non-receptor type 7
chr10_+_14523062 3.96 ENSMUST00000096020.5
predicted gene 10335
chr2_+_14873656 3.91 ENSMUST00000114718.1
ENSMUST00000114719.1
calcium channel, voltage-dependent, beta 2 subunit
chr3_-_116253467 3.80 ENSMUST00000090473.5
G-protein coupled receptor 88
chr7_+_142442330 3.79 ENSMUST00000149529.1
troponin I, skeletal, fast 2
chr11_+_104577281 3.76 ENSMUST00000106956.3
myosin, light polypeptide 4
chr12_-_17176888 3.67 ENSMUST00000170580.1
potassium voltage-gated channel, subfamily F, member 1
chrX_+_160390684 3.61 ENSMUST00000112408.2
ENSMUST00000112402.1
ENSMUST00000112401.1
ENSMUST00000112400.1
ENSMUST00000112405.2
ENSMUST00000112404.2
ENSMUST00000146805.1
G protein-coupled receptor 64
chr4_+_45184815 3.57 ENSMUST00000134280.1
ENSMUST00000044773.5
FERM and PDZ domain containing 1
chr13_-_95444827 3.52 ENSMUST00000045583.7
corticotropin releasing hormone binding protein
chr11_-_46312220 3.42 ENSMUST00000129474.1
ENSMUST00000093166.4
ENSMUST00000165599.2
cytoplasmic FMR1 interacting protein 2
chr8_+_45885479 3.41 ENSMUST00000034053.5
PDZ and LIM domain 3
chrX_-_139871637 3.40 ENSMUST00000033811.7
ENSMUST00000087401.5
microrchidia 4
chr11_+_76998595 3.30 ENSMUST00000108402.2
ENSMUST00000021195.4
solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
chr4_-_43523388 3.29 ENSMUST00000107913.3
ENSMUST00000030184.5
tropomyosin 2, beta
chr8_-_122699066 3.26 ENSMUST00000127984.1
core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)
chr11_+_104576965 3.22 ENSMUST00000106957.1
myosin, light polypeptide 4
chr11_-_69605829 3.22 ENSMUST00000047889.6
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr2_+_103970115 3.20 ENSMUST00000111143.1
ENSMUST00000138815.1
LIM domain only 2
chr9_-_107985863 3.19 ENSMUST00000048568.4
family with sequence similarity 212, member A
chr5_+_21543525 3.16 ENSMUST00000035651.4
leucine rich repeat containing 17
chr7_+_142471838 3.13 ENSMUST00000038946.2
lymphocyte specific 1
chr12_-_115790884 3.11 ENSMUST00000081809.5
immunoglobulin heavy variable 1-73
chr5_-_113830422 3.10 ENSMUST00000100874.4
selectin, platelet (p-selectin) ligand
chr12_-_79007276 3.07 ENSMUST00000056660.6
ENSMUST00000174721.1
transmembrane protein 229B
chr7_+_142472080 3.00 ENSMUST00000105966.1
lymphocyte specific 1
chr17_+_75178797 3.00 ENSMUST00000112516.1
ENSMUST00000135447.1
latent transforming growth factor beta binding protein 1
chr12_+_9574437 3.00 ENSMUST00000057021.7
odd-skipped related 1 (Drosophila)
chr7_-_25005895 2.98 ENSMUST00000102858.3
ENSMUST00000080882.6
ATPase, Na+/K+ transporting, alpha 3 polypeptide
chr7_+_19291070 2.97 ENSMUST00000108468.3
reticulon 2 (Z-band associated protein)
chr19_+_47178820 2.96 ENSMUST00000111808.3
neuralized homolog 1A (Drosophila)
chr4_-_43523746 2.95 ENSMUST00000150592.1
tropomyosin 2, beta
chrX_+_101449078 2.94 ENSMUST00000033674.5
integrin beta 1 binding protein 2
chr2_-_164779721 2.93 ENSMUST00000103095.4
troponin C2, fast
chr7_+_19411086 2.81 ENSMUST00000003643.1
creatine kinase, muscle
chr17_+_29318850 2.80 ENSMUST00000114701.2
peptidase inhibitor 16
chr9_+_121777607 2.77 ENSMUST00000098272.2
kelch-like 40
chr2_+_103970221 2.76 ENSMUST00000111140.2
ENSMUST00000111139.2
LIM domain only 2
chr13_-_117025505 2.75 ENSMUST00000022239.6
poly (ADP-ribose) polymerase family, member 8
chr18_+_60963517 2.69 ENSMUST00000115295.2
ENSMUST00000039904.6
calcium/calmodulin-dependent protein kinase II alpha
chr1_+_129273344 2.68 ENSMUST00000073527.6
ENSMUST00000040311.7
thrombospondin, type I, domain containing 7B
chr17_+_75178911 2.65 ENSMUST00000112514.1
latent transforming growth factor beta binding protein 1
chr17_-_48432723 2.65 ENSMUST00000046549.3
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2
chrX_-_73659724 2.65 ENSMUST00000114473.1
ENSMUST00000002087.7
pregnancy upregulated non-ubiquitously expressed CaM kinase
chr11_+_113619318 2.64 ENSMUST00000146390.2
ENSMUST00000106630.1
somatostatin receptor 2
chr7_+_102101736 2.64 ENSMUST00000033300.2
ADP-ribosyltransferase 1
chr1_-_119053339 2.63 ENSMUST00000161301.1
ENSMUST00000161451.1
ENSMUST00000162607.1
GLI-Kruppel family member GLI2
chr3_-_75270073 2.62 ENSMUST00000039047.4
serine (or cysteine) peptidase inhibitor, clade I, member 2
chr4_-_133872304 2.62 ENSMUST00000157067.2
ribosomal protein S6 kinase polypeptide 1
chr1_+_75375271 2.60 ENSMUST00000087122.5
SPEG complex locus
chr11_+_69965396 2.58 ENSMUST00000018713.6
claudin 7
chr3_+_95588990 2.56 ENSMUST00000177399.1
golgi phosphoprotein 3-like
chr10_+_128909866 2.55 ENSMUST00000026407.7
CD63 antigen
chr8_+_36094828 2.51 ENSMUST00000110492.1
DNA segment, Chr 8, ERATO Doi 82, expressed
chr2_+_174760619 2.50 ENSMUST00000029030.2
endothelin 3
chr11_-_95514570 2.48 ENSMUST00000058866.7
neurexophilin 3
chr11_+_32205483 2.48 ENSMUST00000121182.1
small nuclear ribonucleoprotein 25 (U11/U12)
chr1_-_167393826 2.45 ENSMUST00000028005.2
microsomal glutathione S-transferase 3
chr3_+_146404631 2.45 ENSMUST00000106153.2
ENSMUST00000039021.4
ENSMUST00000106151.1
ENSMUST00000149262.1
synovial sarcoma, X breakpoint 2 interacting protein
chr2_-_33431324 2.44 ENSMUST00000113158.1
zinc finger and BTB domain containing 34
chr3_-_68870266 2.42 ENSMUST00000166328.1
predicted gene, 17641
chr6_+_39420378 2.41 ENSMUST00000090237.2
predicted gene 10244
chrX_-_150812715 2.38 ENSMUST00000112697.3
melanoma antigen, family D, 2
chr11_+_32205411 2.37 ENSMUST00000039601.3
ENSMUST00000149043.1
small nuclear ribonucleoprotein 25 (U11/U12)
chr1_+_135836380 2.36 ENSMUST00000178204.1
troponin T2, cardiac
chr4_-_133967235 2.33 ENSMUST00000123234.1
high mobility group nucleosomal binding domain 2
chr6_-_39420281 2.32 ENSMUST00000114822.1
ENSMUST00000051671.4
makorin, ring finger protein, 1
chr1_-_119053619 2.31 ENSMUST00000062483.8
GLI-Kruppel family member GLI2
chr8_-_84176552 2.31 ENSMUST00000070102.5
nanos homolog 3 (Drosophila)
chr13_-_56178864 2.31 ENSMUST00000169652.1
TRAF-interacting protein with forkhead-associated domain, family member B
chr6_-_39420418 2.27 ENSMUST00000031985.6
makorin, ring finger protein, 1
chr4_-_43523595 2.25 ENSMUST00000107914.3
tropomyosin 2, beta
chr3_+_146404978 2.23 ENSMUST00000129978.1
synovial sarcoma, X breakpoint 2 interacting protein
chr11_-_94474088 2.21 ENSMUST00000107786.1
ENSMUST00000107791.1
ENSMUST00000103166.2
ENSMUST00000107792.1
ENSMUST00000100561.3
ENSMUST00000107793.1
ENSMUST00000107788.1
ENSMUST00000107790.1
ENSMUST00000107789.1
ENSMUST00000107785.1
ENSMUST00000021234.8
calcium channel, voltage-dependent, T type, alpha 1G subunit
chr5_-_137212389 2.19 ENSMUST00000179412.1
RIKEN cDNA A630081J09 gene
chr13_-_70841790 2.18 ENSMUST00000080145.6
ENSMUST00000109694.2
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 16
chr3_-_126998408 2.17 ENSMUST00000182764.1
ENSMUST00000044443.8
ankyrin 2, brain
chr13_+_23544052 2.16 ENSMUST00000075558.2
histone cluster 1, H3f
chr4_-_133967296 2.16 ENSMUST00000105893.1
high mobility group nucleosomal binding domain 2
chr4_+_133240778 2.14 ENSMUST00000030677.6
mitogen-activated protein kinase kinase kinase 6
chr7_+_30422389 2.13 ENSMUST00000108175.1
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, delta
chr12_-_32208470 2.13 ENSMUST00000085469.5
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr3_+_95588928 2.12 ENSMUST00000177390.1
ENSMUST00000098861.4
ENSMUST00000060323.5
golgi phosphoprotein 3-like
chr3_+_152165374 2.11 ENSMUST00000181854.1
RIKEN cDNA D630002J18 gene
chr15_-_77643270 2.11 ENSMUST00000181154.1
ENSMUST00000180949.1
ENSMUST00000181467.1
ENSMUST00000166623.2
apolipoprotein L 11b
chr15_-_96642883 2.10 ENSMUST00000088452.4
solute carrier family 38, member 1
chrX_-_36989656 2.10 ENSMUST00000060474.7
ENSMUST00000053456.4
ENSMUST00000115239.3
septin 6
chr6_+_49367739 2.08 ENSMUST00000060561.8
ENSMUST00000121903.1
ENSMUST00000134786.1
family with sequence similarity 221, member A
chrX_-_57338598 2.07 ENSMUST00000033468.4
ENSMUST00000114736.1
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr17_-_78906899 2.06 ENSMUST00000042683.6
ENSMUST00000169544.1
sulfotransferase family, cytosolic, 6B, member 1
chr6_-_39419967 2.05 ENSMUST00000122996.1
makorin, ring finger protein, 1
chr7_+_45639964 2.04 ENSMUST00000148532.1
MEF2 activating motif and SAP domain containing transcriptional regulator
chr12_-_32953772 2.02 ENSMUST00000180391.1
ENSMUST00000181670.1
RIKEN cDNA 4933406C10 gene
chr5_-_135251209 2.01 ENSMUST00000062572.2
frizzled homolog 9 (Drosophila)
chr4_-_133968611 2.00 ENSMUST00000102552.1
high mobility group nucleosomal binding domain 2
chr3_+_95588960 1.99 ENSMUST00000176674.1
ENSMUST00000177389.1
ENSMUST00000176755.1
golgi phosphoprotein 3-like
chr3_+_123446913 1.99 ENSMUST00000029603.8
protease, serine, 12 neurotrypsin (motopsin)
chr4_-_156059414 1.98 ENSMUST00000184348.1
tubulin tyrosine ligase-like family, member 10
chr12_+_113014502 1.98 ENSMUST00000084891.4
phosphofurin acidic cluster sorting protein 2
chrX_-_150812932 1.97 ENSMUST00000131241.1
ENSMUST00000147152.1
ENSMUST00000143843.1
melanoma antigen, family D, 2
chr13_+_21810428 1.97 ENSMUST00000091745.5
histone cluster 1, H2ao
chr5_-_131538687 1.96 ENSMUST00000161374.1
autism susceptibility candidate 2
chr5_+_105415738 1.94 ENSMUST00000112707.1
leucine rich repeat containing 8 family, member B
chr4_-_3938354 1.92 ENSMUST00000003369.3
pleiomorphic adenoma gene 1
chr12_+_110279228 1.89 ENSMUST00000097228.4
deiodinase, iodothyronine type III
chr4_+_140906344 1.89 ENSMUST00000030765.6
peptidyl arginine deiminase, type II
chr5_+_34989473 1.88 ENSMUST00000114284.1
ENSMUST00000114285.1
regulator of G-protein signaling 12
chr11_-_70322520 1.88 ENSMUST00000019051.2
arachidonate lipoxygenase, epidermal
chr5_-_73256555 1.86 ENSMUST00000171179.1
ENSMUST00000101127.5
furry homolog-like (Drosophila)
furry homolog-like (Drosophila)
chr3_+_146404844 1.84 ENSMUST00000106149.1
synovial sarcoma, X breakpoint 2 interacting protein
chr8_-_40634750 1.83 ENSMUST00000173957.1
myotubularin related protein 7
chr5_+_144545883 1.78 ENSMUST00000071782.6
neuronal pentraxin 2
chr9_+_30942541 1.78 ENSMUST00000068135.6
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 8
chr2_-_131187282 1.78 ENSMUST00000028801.1
sperm flagellar 1
chr3_-_27153782 1.77 ENSMUST00000175857.1
ENSMUST00000177055.1
ENSMUST00000176535.1
ect2 oncogene
chr2_-_27072175 1.76 ENSMUST00000009358.2
transmembrane protein 8C
chr11_+_96929367 1.75 ENSMUST00000062172.5
proline rich 15-like
chr4_+_119814495 1.75 ENSMUST00000106307.2
human immunodeficiency virus type I enhancer binding protein 3
chr12_-_32208609 1.74 ENSMUST00000053215.7
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr1_-_166127876 1.73 ENSMUST00000085992.2
dual specificity phosphatase 27 (putative)
chr6_+_118066356 1.72 ENSMUST00000164960.1
RasGEF domain family, member 1A
chr5_-_114773488 1.71 ENSMUST00000178440.1
ENSMUST00000043283.7
ENSMUST00000112185.2
G protein-coupled receptor kinase-interactor 2
chr15_-_101712891 1.70 ENSMUST00000023709.5
keratin 5
chr2_+_49787675 1.67 ENSMUST00000028103.6
LY6/PLAUR domain containing 6B
chr3_-_27153844 1.67 ENSMUST00000176242.2
ENSMUST00000176780.1
ect2 oncogene
chr3_-_27153861 1.66 ENSMUST00000108300.1
ENSMUST00000108298.2
ect2 oncogene
chr6_-_53068562 1.65 ENSMUST00000074541.5
JAZF zinc finger 1
chr15_+_77477044 1.65 ENSMUST00000060551.2
ENSMUST00000119997.1
apolipoprotein L 10A
chr6_+_112459501 1.64 ENSMUST00000075477.6
caveolin 3
chr17_-_72603709 1.64 ENSMUST00000086639.4
anaplastic lymphoma kinase
chr6_-_87496279 1.63 ENSMUST00000101197.2
Rho GTPase activating protein 25
chr19_+_53529100 1.62 ENSMUST00000038287.6
dual specificity phosphatase 5
chr15_-_78773452 1.61 ENSMUST00000018313.5
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr4_+_130915949 1.61 ENSMUST00000030316.6
lysosomal-associated protein transmembrane 5
chr17_+_28142267 1.61 ENSMUST00000043503.3
signal peptide, CUB domain, EGF-like 3

Network of associatons between targets according to the STRING database.

First level regulatory network of Tcf3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 6.6 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
1.6 7.9 GO:0046882 negative regulation of follicle-stimulating hormone secretion(GO:0046882)
1.5 11.8 GO:0007144 female meiosis I(GO:0007144)
1.3 4.0 GO:0002017 regulation of blood volume by renal aldosterone(GO:0002017)
1.3 3.9 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
1.2 4.9 GO:0060032 notochord regression(GO:0060032)
1.2 6.1 GO:0006564 L-serine biosynthetic process(GO:0006564)
1.2 3.5 GO:0071314 cellular response to cocaine(GO:0071314)
1.1 48.6 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
1.1 3.3 GO:0014064 positive regulation of serotonin secretion(GO:0014064)
1.0 4.0 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
1.0 3.0 GO:0072194 intermediate mesoderm development(GO:0048389) pattern specification involved in mesonephros development(GO:0061227) anterior/posterior pattern specification involved in kidney development(GO:0072098) kidney smooth muscle tissue development(GO:0072194)
1.0 3.8 GO:0061743 motor learning(GO:0061743)
0.9 6.5 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.9 4.4 GO:0070103 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) regulation of interleukin-6-mediated signaling pathway(GO:0070103)
0.9 2.6 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.8 4.1 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.8 3.2 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.8 7.2 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.8 2.4 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.8 3.8 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.7 7.5 GO:0090527 actin filament reorganization(GO:0090527)
0.7 2.2 GO:0003345 proepicardium cell migration involved in pericardium morphogenesis(GO:0003345)
0.7 1.4 GO:0035582 sequestering of BMP in extracellular matrix(GO:0035582)
0.7 4.1 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.7 4.1 GO:0014826 regulation of systemic arterial blood pressure by endothelin(GO:0003100) vein smooth muscle contraction(GO:0014826)
0.7 10.2 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.7 2.0 GO:1990523 bone regeneration(GO:1990523)
0.7 2.0 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.6 1.2 GO:0002554 serotonin secretion by platelet(GO:0002554)
0.6 2.3 GO:0007356 thorax and anterior abdomen determination(GO:0007356)
0.6 3.9 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
0.6 5.5 GO:0060923 cardiac muscle cell fate commitment(GO:0060923)
0.6 2.2 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.5 1.6 GO:0035995 detection of muscle stretch(GO:0035995)
0.5 1.6 GO:0036269 swimming behavior(GO:0036269)
0.5 4.9 GO:0036309 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.5 4.4 GO:0070294 renal sodium ion absorption(GO:0070294)
0.5 15.1 GO:0045780 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.5 2.6 GO:2000680 regulation of rubidium ion transport(GO:2000680)
0.5 1.5 GO:0043397 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) positive regulation of corticotropin-releasing hormone secretion(GO:0051466) regulation of G-protein coupled receptor internalization(GO:1904020)
0.5 3.0 GO:0036376 sodium ion export from cell(GO:0036376)
0.5 5.9 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.5 3.8 GO:0048539 bone marrow development(GO:0048539)
0.5 1.4 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.4 6.7 GO:0048194 Golgi vesicle budding(GO:0048194)
0.4 1.3 GO:0072061 inner medullary collecting duct development(GO:0072061)
0.4 3.4 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.4 2.1 GO:0006868 glutamine transport(GO:0006868)
0.4 1.2 GO:0051385 response to mineralocorticoid(GO:0051385)
0.4 1.6 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.4 1.2 GO:0006227 dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate metabolic process(GO:0009138) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077)
0.4 1.2 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.4 3.8 GO:0030432 peristalsis(GO:0030432)
0.4 1.5 GO:1902303 negative regulation of potassium ion export(GO:1902303)
0.4 1.9 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414) negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.4 1.9 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.4 6.0 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.4 6.5 GO:0046514 ceramide catabolic process(GO:0046514)
0.4 1.1 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.4 7.6 GO:1900151 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.4 1.4 GO:0033580 protein glycosylation at cell surface(GO:0033575) protein galactosylation at cell surface(GO:0033580) protein galactosylation(GO:0042125)
0.3 1.0 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.3 4.0 GO:0061032 visceral serous pericardium development(GO:0061032)
0.3 0.7 GO:0050917 sensory perception of umami taste(GO:0050917)
0.3 1.3 GO:1901594 detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594)
0.3 2.0 GO:0018094 protein polyglycylation(GO:0018094)
0.3 4.3 GO:0048733 sebaceous gland development(GO:0048733)
0.3 1.3 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.3 8.8 GO:0015701 bicarbonate transport(GO:0015701)
0.3 1.3 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.3 0.9 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.3 3.3 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.3 2.9 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.3 0.9 GO:0071462 cellular response to mercury ion(GO:0071288) cellular response to water stimulus(GO:0071462)
0.3 5.1 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.3 0.8 GO:2000554 regulation of T-helper 1 cell cytokine production(GO:2000554) positive regulation of T-helper 1 cell cytokine production(GO:2000556)
0.3 1.6 GO:0002317 plasma cell differentiation(GO:0002317)
0.3 0.5 GO:0072034 renal vesicle induction(GO:0072034)
0.3 0.8 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.3 3.8 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.2 1.0 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.2 2.0 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.2 3.6 GO:0030322 stabilization of membrane potential(GO:0030322)
0.2 2.1 GO:2000399 negative regulation of T cell differentiation in thymus(GO:0033085) negative regulation of thymocyte aggregation(GO:2000399)
0.2 0.7 GO:0033082 regulation of extrathymic T cell differentiation(GO:0033082)
0.2 1.2 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.2 7.0 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.2 0.7 GO:0003032 detection of oxygen(GO:0003032)
0.2 0.9 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.2 9.8 GO:0003009 skeletal muscle contraction(GO:0003009)
0.2 6.5 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.2 0.6 GO:0002678 positive regulation of chronic inflammatory response(GO:0002678) regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.2 0.6 GO:0006713 glucocorticoid catabolic process(GO:0006713)
0.2 0.6 GO:0006601 creatine biosynthetic process(GO:0006601)
0.2 2.8 GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.2 2.4 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.2 5.7 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.2 0.6 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.2 5.2 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.2 1.9 GO:0019336 phenol-containing compound catabolic process(GO:0019336)
0.2 5.3 GO:0030903 notochord development(GO:0030903)
0.2 1.9 GO:0019372 lipoxygenase pathway(GO:0019372)
0.2 0.6 GO:0046122 germinal center B cell differentiation(GO:0002314) adenosine catabolic process(GO:0006154) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) purine nucleobase salvage(GO:0043096) hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101) purine deoxyribonucleoside metabolic process(GO:0046122) regulation of adenosine receptor signaling pathway(GO:0060167) negative regulation of mucus secretion(GO:0070256)
0.2 1.1 GO:1901678 iron coordination entity transport(GO:1901678)
0.2 3.6 GO:0080111 DNA demethylation(GO:0080111)
0.2 1.3 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.2 0.3 GO:0099541 retrograde trans-synaptic signaling(GO:0098917) trans-synaptic signaling by lipid(GO:0099541) trans-synaptic signaling by endocannabinoid(GO:0099542)
0.2 2.6 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.2 0.5 GO:1901675 response to methylglyoxal(GO:0051595) negative regulation of histone H3-K27 acetylation(GO:1901675)
0.2 0.3 GO:0072236 metanephric loop of Henle development(GO:0072236)
0.2 3.3 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.1 0.4 GO:1903438 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.1 18.1 GO:0007586 digestion(GO:0007586)
0.1 0.4 GO:0045819 plasmacytoid dendritic cell activation(GO:0002270) positive regulation of glycogen catabolic process(GO:0045819)
0.1 0.4 GO:0043974 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
0.1 0.8 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.1 1.5 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.1 0.4 GO:0060720 spongiotrophoblast cell proliferation(GO:0060720) cell proliferation involved in embryonic placenta development(GO:0060722)
0.1 0.7 GO:0098909 regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.1 0.5 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.1 0.8 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 1.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.6 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.1 3.8 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 0.5 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.1 1.0 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.1 0.8 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.1 1.6 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.9 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.1 0.5 GO:0032202 telomere assembly(GO:0032202) scaRNA localization to Cajal body(GO:0090666)
0.1 1.6 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.1 1.3 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804)
0.1 1.4 GO:0060033 anatomical structure regression(GO:0060033)
0.1 1.1 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.1 0.5 GO:0002121 inter-male aggressive behavior(GO:0002121)
0.1 1.7 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 0.4 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.1 3.5 GO:0000186 activation of MAPKK activity(GO:0000186)
0.1 0.5 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) negative regulation of serotonin uptake(GO:0051612)
0.1 1.0 GO:0035608 protein deglutamylation(GO:0035608)
0.1 0.6 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 0.6 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.1 0.3 GO:0014827 intestine smooth muscle contraction(GO:0014827)
0.1 1.3 GO:0044146 negative regulation of growth of symbiont involved in interaction with host(GO:0044146)
0.1 0.6 GO:0060666 pulmonary myocardium development(GO:0003350) dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 1.6 GO:0060539 diaphragm development(GO:0060539)
0.1 0.7 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.1 1.1 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.1 0.2 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.1 0.6 GO:0061577 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577)
0.1 0.9 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 0.5 GO:0060017 parathyroid gland development(GO:0060017)
0.1 0.6 GO:0014850 response to muscle activity(GO:0014850)
0.1 0.3 GO:0071500 cellular response to nitrosative stress(GO:0071500)
0.1 0.7 GO:1990118 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 1.5 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1 0.4 GO:0098964 dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964)
0.1 2.6 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.1 0.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 1.1 GO:0032060 bleb assembly(GO:0032060)
0.1 0.4 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.1 1.4 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.1 0.7 GO:2000194 regulation of female gonad development(GO:2000194)
0.1 0.3 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.1 1.3 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.1 1.4 GO:0043496 regulation of protein homodimerization activity(GO:0043496)
0.1 1.0 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.1 0.4 GO:0014857 regulation of skeletal muscle satellite cell proliferation(GO:0014842) regulation of skeletal muscle cell proliferation(GO:0014857)
0.1 0.2 GO:0072162 metanephric mesenchymal cell differentiation(GO:0072162)
0.0 2.8 GO:0048747 muscle fiber development(GO:0048747)
0.0 0.1 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.0 0.3 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0 0.7 GO:0060065 uterus development(GO:0060065)
0.0 0.9 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.5 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 4.0 GO:0042100 B cell proliferation(GO:0042100)
0.0 0.4 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.5 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.3 GO:2000121 regulation of removal of superoxide radicals(GO:2000121)
0.0 1.5 GO:0000154 rRNA modification(GO:0000154)
0.0 0.6 GO:0071548 response to dexamethasone(GO:0071548) cellular response to dexamethasone stimulus(GO:0071549)
0.0 1.0 GO:0045109 intermediate filament organization(GO:0045109)
0.0 0.4 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.0 0.2 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.3 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.3 GO:0043201 response to leucine(GO:0043201) cellular response to leucine(GO:0071233)
0.0 1.0 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.8 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 3.6 GO:0006342 chromatin silencing(GO:0006342)
0.0 0.4 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465)
0.0 0.1 GO:1903998 regulation of eating behavior(GO:1903998) negative regulation of eating behavior(GO:1903999)
0.0 0.7 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.0 0.7 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.1 GO:0002159 desmosome assembly(GO:0002159)
0.0 1.2 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 4.2 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 0.1 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089) cellular response to actinomycin D(GO:0072717)
0.0 0.7 GO:0048266 behavioral response to pain(GO:0048266)
0.0 0.5 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 0.1 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.7 GO:0060004 reflex(GO:0060004)
0.0 4.3 GO:0006936 muscle contraction(GO:0006936)
0.0 1.7 GO:1902017 regulation of cilium assembly(GO:1902017)
0.0 0.4 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.7 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 0.1 GO:0042637 catagen(GO:0042637)
0.0 0.8 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.1 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.6 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.0 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593)
0.0 0.1 GO:0072513 semicircular canal morphogenesis(GO:0048752) positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.4 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.7 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.1 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.0 0.6 GO:0000266 mitochondrial fission(GO:0000266)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 7.9 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
2.1 48.0 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
1.9 5.7 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
1.4 4.3 GO:0071149 TEAD-2-YAP complex(GO:0071149)
1.0 5.1 GO:0097149 centralspindlin complex(GO:0097149)
1.0 3.9 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
1.0 17.3 GO:0005861 troponin complex(GO:0005861)
0.8 0.8 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.7 3.0 GO:0014802 terminal cisterna(GO:0014802)
0.7 2.1 GO:0005940 septin ring(GO:0005940)
0.7 6.2 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.7 2.7 GO:0099522 region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524)
0.7 8.5 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.6 2.6 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.6 6.8 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.5 1.5 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.5 4.5 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.4 1.2 GO:0005595 collagen type XII trimer(GO:0005595) anchoring collagen complex(GO:0030934)
0.4 1.1 GO:0005955 calcineurin complex(GO:0005955)
0.4 4.9 GO:0097542 ciliary tip(GO:0097542)
0.3 19.2 GO:0031672 A band(GO:0031672)
0.3 3.1 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.3 0.8 GO:0044302 dentate gyrus mossy fiber(GO:0044302)
0.2 1.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.2 1.5 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.2 0.6 GO:0005607 laminin-2 complex(GO:0005607)
0.2 0.9 GO:0031166 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.2 3.5 GO:0005767 secondary lysosome(GO:0005767)
0.2 5.9 GO:0042588 zymogen granule(GO:0042588)
0.2 3.5 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.2 6.1 GO:0034451 centriolar satellite(GO:0034451)
0.2 2.0 GO:0043083 synaptic cleft(GO:0043083)
0.2 7.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.2 1.0 GO:0005663 DNA replication factor C complex(GO:0005663)
0.2 0.7 GO:1990357 terminal web(GO:1990357)
0.2 4.8 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.2 3.9 GO:0099634 postsynaptic specialization membrane(GO:0099634)
0.1 0.9 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.1 0.5 GO:0097512 cardiac myofibril(GO:0097512)
0.1 1.0 GO:0001940 male pronucleus(GO:0001940)
0.1 1.5 GO:0044294 dendritic growth cone(GO:0044294)
0.1 2.2 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 2.0 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 7.7 GO:0014704 intercalated disc(GO:0014704)
0.1 1.4 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 7.5 GO:0031985 Golgi cisterna(GO:0031985)
0.1 4.6 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 4.1 GO:0097440 apical dendrite(GO:0097440)
0.1 1.9 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 0.5 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.1 0.3 GO:0071953 elastic fiber(GO:0071953)
0.1 1.1 GO:0043218 compact myelin(GO:0043218)
0.1 1.1 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 3.5 GO:0030315 T-tubule(GO:0030315)
0.1 2.1 GO:0005795 Golgi stack(GO:0005795)
0.1 0.9 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 0.4 GO:0034709 methylosome(GO:0034709)
0.1 9.1 GO:0000922 spindle pole(GO:0000922)
0.1 4.7 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 8.9 GO:0005819 spindle(GO:0005819)
0.1 1.0 GO:0016460 myosin II complex(GO:0016460)
0.1 6.3 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 0.3 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 1.0 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.4 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.4 GO:0061574 ASAP complex(GO:0061574)
0.0 2.3 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 1.0 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 8.3 GO:0030427 site of polarized growth(GO:0030427)
0.0 2.5 GO:0030018 Z disc(GO:0030018)
0.0 1.2 GO:0001533 cornified envelope(GO:0001533)
0.0 3.6 GO:0016605 PML body(GO:0016605)
0.0 7.5 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 1.1 GO:0031941 filamentous actin(GO:0031941)
0.0 3.7 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 1.2 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 1.2 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.3 GO:0016235 aggresome(GO:0016235)
0.0 49.3 GO:0005615 extracellular space(GO:0005615)
0.0 0.5 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 2.0 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.0 0.2 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.5 GO:0032590 dendrite membrane(GO:0032590)
0.0 7.5 GO:0016607 nuclear speck(GO:0016607)
0.0 0.2 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 1.2 GO:0005814 centriole(GO:0005814)
0.0 1.5 GO:0005930 axoneme(GO:0005930)
0.0 0.1 GO:0005883 neurofilament(GO:0005883)
0.0 0.3 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.3 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.6 GO:0005604 basement membrane(GO:0005604)
0.0 0.6 GO:0042383 sarcolemma(GO:0042383)
0.0 0.7 GO:0005875 microtubule associated complex(GO:0005875)
0.0 0.7 GO:0000786 nucleosome(GO:0000786)
0.0 0.4 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.8 GO:0032993 protein-DNA complex(GO:0032993)
0.0 2.2 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.3 43.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
2.0 5.9 GO:0004771 sterol esterase activity(GO:0004771) retinyl-palmitate esterase activity(GO:0050253)
1.6 12.6 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
1.3 4.0 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
1.2 6.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
1.2 12.0 GO:0031014 troponin T binding(GO:0031014)
1.1 3.3 GO:0005330 dopamine:sodium symporter activity(GO:0005330)
1.0 4.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.7 6.6 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.7 6.5 GO:0034711 inhibin binding(GO:0034711)
0.7 4.1 GO:0035184 histone threonine kinase activity(GO:0035184)
0.7 2.0 GO:0070737 protein-glycine ligase activity, elongating(GO:0070737)
0.6 1.9 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.6 2.4 GO:0030172 troponin C binding(GO:0030172)
0.6 1.7 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.6 6.2 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.5 1.6 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.5 1.6 GO:0048030 disaccharide binding(GO:0048030)
0.5 2.6 GO:0004994 somatostatin receptor activity(GO:0004994)
0.5 4.0 GO:0043559 insulin binding(GO:0043559)
0.5 15.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.5 1.9 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.5 2.8 GO:0004111 creatine kinase activity(GO:0004111)
0.4 2.7 GO:0004126 cytidine deaminase activity(GO:0004126)
0.4 8.8 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.4 1.7 GO:0050436 microfibril binding(GO:0050436)
0.4 2.1 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.4 1.2 GO:0009041 uridylate kinase activity(GO:0009041)
0.4 1.9 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.4 3.3 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.4 3.9 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.3 1.0 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.3 1.3 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
0.3 6.0 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.3 5.2 GO:0043495 protein anchor(GO:0043495)
0.3 1.2 GO:0019767 IgE receptor activity(GO:0019767)
0.3 1.2 GO:0038100 nodal binding(GO:0038100)
0.3 11.0 GO:0008307 structural constituent of muscle(GO:0008307)
0.3 2.7 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.3 1.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.3 1.3 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.3 2.6 GO:0008046 axon guidance receptor activity(GO:0008046)
0.3 1.5 GO:0000155 phosphorelay sensor kinase activity(GO:0000155) voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.2 2.7 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.2 1.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.2 1.7 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.2 1.4 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.2 4.4 GO:0004180 carboxypeptidase activity(GO:0004180)
0.2 3.6 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.2 0.9 GO:0052743 inositol tetrakisphosphate phosphatase activity(GO:0052743)
0.2 5.3 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.2 1.3 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.2 0.9 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.2 2.0 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.2 5.4 GO:0030506 ankyrin binding(GO:0030506)
0.2 1.0 GO:0052724 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.2 5.4 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.2 1.2 GO:0045340 mercury ion binding(GO:0045340)
0.2 4.3 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.2 0.9 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.2 1.3 GO:0000150 recombinase activity(GO:0000150)
0.2 0.9 GO:1904288 BAT3 complex binding(GO:1904288)
0.2 6.7 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.2 10.2 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.2 0.7 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.2 3.0 GO:0051861 glycolipid binding(GO:0051861)
0.2 1.5 GO:0033691 sialic acid binding(GO:0033691)
0.2 1.0 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.2 1.1 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 3.5 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 0.7 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.1 2.2 GO:0045499 chemorepellent activity(GO:0045499)
0.1 1.2 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.1 0.6 GO:0070052 collagen V binding(GO:0070052)
0.1 1.0 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 0.4 GO:0000401 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
0.1 1.4 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 1.9 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 0.4 GO:0034190 apolipoprotein receptor binding(GO:0034190)
0.1 5.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 7.2 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 1.1 GO:0070097 delta-catenin binding(GO:0070097)
0.1 28.1 GO:0008236 serine-type peptidase activity(GO:0008236)
0.1 0.9 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.1 1.9 GO:0031434 MAP-kinase scaffold activity(GO:0005078) mitogen-activated protein kinase kinase binding(GO:0031434)
0.1 0.9 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1 17.5 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.1 1.2 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.1 4.8 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 1.2 GO:0070700 BMP receptor binding(GO:0070700)
0.1 1.3 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 4.3 GO:0003785 actin monomer binding(GO:0003785)
0.1 1.7 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.1 0.8 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.7 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 0.4 GO:2001069 glycogen binding(GO:2001069)
0.1 1.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 1.0 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 1.5 GO:0015197 peptide transporter activity(GO:0015197)
0.1 5.4 GO:0015459 potassium channel regulator activity(GO:0015459)
0.1 0.4 GO:0051425 PTB domain binding(GO:0051425)
0.1 0.5 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.1 0.6 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 0.8 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1 2.5 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 2.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 0.6 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 3.5 GO:0017046 peptide hormone binding(GO:0017046)
0.1 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 3.0 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 0.7 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 0.2 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
0.1 0.8 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 0.8 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.4 GO:0045322 unmethylated CpG binding(GO:0045322)
0.1 0.3 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.1 1.5 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 0.9 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 2.5 GO:0005109 frizzled binding(GO:0005109)
0.1 0.4 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 1.6 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.1 1.2 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.1 0.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 1.2 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.4 GO:0008527 taste receptor activity(GO:0008527)
0.0 0.5 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.9 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.6 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 1.0 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.7 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 1.4 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.0 GO:0051022 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.8 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 3.5 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.3 GO:0001849 complement component C1q binding(GO:0001849)
0.0 1.4 GO:0045182 translation regulator activity(GO:0045182)
0.0 0.6 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 3.4 GO:0001076 transcription factor activity, RNA polymerase II transcription factor binding(GO:0001076)
0.0 0.7 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.5 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 0.1 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.1 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.0 1.2 GO:0050699 WW domain binding(GO:0050699)
0.0 8.5 GO:0005096 GTPase activator activity(GO:0005096)
0.0 1.8 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.5 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 2.0 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 3.5 GO:0030414 peptidase inhibitor activity(GO:0030414)
0.0 0.5 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.2 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.8 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.7 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.4 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 3.5 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.7 GO:0030291 protein serine/threonine kinase inhibitor activity(GO:0030291)
0.0 3.0 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.2 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 2.6 GO:0005125 cytokine activity(GO:0005125)
0.0 5.7 GO:0005525 GTP binding(GO:0005525)
0.0 0.7 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 2.7 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.4 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.1 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 11.8 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.6 12.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.3 8.2 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.3 9.2 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.2 1.1 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.2 14.7 PID RHOA REG PATHWAY Regulation of RhoA activity
0.2 6.0 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.2 4.6 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.2 10.3 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.2 3.2 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.1 3.9 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 3.9 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 3.5 PID EPO PATHWAY EPO signaling pathway
0.1 4.6 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 3.8 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.1 20.9 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 6.0 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 1.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 1.0 PID TNF PATHWAY TNF receptor signaling pathway
0.1 3.5 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 0.4 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 2.7 PID ENDOTHELIN PATHWAY Endothelins
0.1 1.6 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 0.5 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 2.5 PID ERBB4 PATHWAY ErbB4 signaling events
0.1 0.6 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 1.2 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 2.2 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 1.4 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 2.2 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.9 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.8 PID REELIN PATHWAY Reelin signaling pathway
0.0 1.5 PID ATR PATHWAY ATR signaling pathway
0.0 1.0 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.7 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.6 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.4 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 1.2 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.4 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.6 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 1.7 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 1.0 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.3 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 3.1 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.8 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.9 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.5 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 48.9 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.7 6.6 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.7 11.8 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.6 30.7 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.4 8.0 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.4 15.1 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.2 2.6 REACTOME DEFENSINS Genes involved in Defensins
0.2 6.1 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.2 6.5 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.2 4.1 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 2.8 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.1 1.2 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 1.9 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 3.3 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 5.7 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 2.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 4.2 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 3.3 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 3.3 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 1.6 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 1.3 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 2.0 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 3.1 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 1.3 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 2.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 0.7 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.1 5.8 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 1.4 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 9.2 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.5 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.7 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 1.2 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 1.6 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 6.1 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 1.6 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 1.3 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 1.0 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.7 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.6 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 1.0 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.0 1.3 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.3 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.7 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.5 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 1.5 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.5 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 1.2 REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.0 1.1 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 1.3 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.4 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins