Motif ID: Tcf7_Tcf7l2

Z-value: 1.239

Transcription factors associated with Tcf7_Tcf7l2:

Gene SymbolEntrez IDGene Name
Tcf7 ENSMUSG00000000782.9 Tcf7
Tcf7l2 ENSMUSG00000024985.12 Tcf7l2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tcf7mm10_v2_chr11_-_52282564_522825790.774.3e-08Click!
Tcf7l2mm10_v2_chr19_+_55894508_558945340.554.8e-04Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Tcf7_Tcf7l2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_-_145805862 9.487 ENSMUST00000067479.5
Cyp3a44
cytochrome P450, family 3, subfamily a, polypeptide 44
chr14_-_56062307 8.010 ENSMUST00000043249.8
Mcpt4
mast cell protease 4
chr5_-_145469723 6.578 ENSMUST00000031633.4
Cyp3a16
cytochrome P450, family 3, subfamily a, polypeptide 16
chr6_-_40999479 5.331 ENSMUST00000166306.1
Gm2663
predicted gene 2663
chr7_+_13733502 4.647 ENSMUST00000086148.6
Sult2a2
sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 2
chr3_-_107239707 4.486 ENSMUST00000049852.8
Prok1
prokineticin 1
chr17_+_25366550 4.246 ENSMUST00000069616.7
Tpsb2
tryptase beta 2
chr7_-_13989588 3.831 ENSMUST00000165167.1
ENSMUST00000108520.2
Sult2a4

sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 4

chr8_-_111691002 3.709 ENSMUST00000034435.5
Ctrb1
chymotrypsinogen B1
chr11_+_108920800 3.647 ENSMUST00000140821.1
Axin2
axin2
chr5_-_145584723 3.511 ENSMUST00000075837.6
Cyp3a41b
cytochrome P450, family 3, subfamily a, polypeptide 41B
chr7_+_13623967 3.192 ENSMUST00000108525.2
Sult2a5
sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 5
chr18_+_21072329 2.941 ENSMUST00000082235.4
Mep1b
meprin 1 beta
chr7_-_142576492 2.941 ENSMUST00000140716.1
H19
H19 fetal liver mRNA
chr19_+_38132767 2.690 ENSMUST00000025956.5
ENSMUST00000112329.1
Pde6c

phosphodiesterase 6C, cGMP specific, cone, alpha prime

chr8_+_71597648 2.657 ENSMUST00000143662.1
Fam129c
family with sequence similarity 129, member C
chr6_-_69400097 2.505 ENSMUST00000177795.1
Igkv4-62
immunoglobulin kappa variable 4-62
chr9_+_46240696 2.484 ENSMUST00000034585.6
Apoa4
apolipoprotein A-IV
chr7_-_142657466 2.428 ENSMUST00000097936.2
ENSMUST00000000033.5
Igf2

insulin-like growth factor 2

chr6_+_129591782 2.326 ENSMUST00000112063.2
ENSMUST00000032268.7
ENSMUST00000119520.1
Klrd1


killer cell lectin-like receptor, subfamily D, member 1


chr6_+_115422040 2.280 ENSMUST00000000450.3
Pparg
peroxisome proliferator activated receptor gamma
chr9_-_96719549 2.243 ENSMUST00000128269.1
Zbtb38
zinc finger and BTB domain containing 38
chr11_-_99322943 2.119 ENSMUST00000038004.2
Krt25
keratin 25
chr7_-_142656018 2.045 ENSMUST00000178921.1
Igf2
insulin-like growth factor 2
chrX_+_6415736 1.999 ENSMUST00000143641.3
Shroom4
shroom family member 4
chr7_+_45216671 1.991 ENSMUST00000134420.1
Tead2
TEA domain family member 2
chr2_+_96318014 1.884 ENSMUST00000135431.1
ENSMUST00000162807.2
Lrrc4c

leucine rich repeat containing 4C

chr1_+_88166004 1.880 ENSMUST00000097659.4
Ugt1a5
UDP glucuronosyltransferase 1 family, polypeptide A5
chr14_-_70323783 1.835 ENSMUST00000151011.1
Slc39a14
solute carrier family 39 (zinc transporter), member 14
chr2_-_150255591 1.826 ENSMUST00000063463.5
Gm21994
predicted gene 21994
chr10_-_128960965 1.754 ENSMUST00000026398.3
Mettl7b
methyltransferase like 7B
chr6_+_78405148 1.746 ENSMUST00000023906.2
Reg2
regenerating islet-derived 2
chr7_-_31076656 1.724 ENSMUST00000167369.1
Fxyd3
FXYD domain-containing ion transport regulator 3
chr16_-_45492962 1.710 ENSMUST00000114585.2
Gm609
predicted gene 609
chr5_-_44102032 1.673 ENSMUST00000171543.1
Prom1
prominin 1
chr6_-_69284319 1.660 ENSMUST00000103349.1
Igkv4-69
immunoglobulin kappa variable 4-69
chr8_+_21734490 1.655 ENSMUST00000080533.5
Defa24
defensin, alpha, 24
chr19_+_39992424 1.644 ENSMUST00000049178.2
Cyp2c37
cytochrome P450, family 2. subfamily c, polypeptide 37
chr5_-_62765618 1.638 ENSMUST00000159470.1
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr6_+_40964760 1.595 ENSMUST00000076638.5
1810009J06Rik
RIKEN cDNA 1810009J06 gene
chr13_+_65512678 1.561 ENSMUST00000081471.2
Gm10139
predicted gene 10139
chr10_-_127370535 1.542 ENSMUST00000026472.8
Inhbc
inhibin beta-C
chr19_+_18749983 1.530 ENSMUST00000040489.7
Trpm6
transient receptor potential cation channel, subfamily M, member 6
chr11_+_108921648 1.511 ENSMUST00000144511.1
Axin2
axin2
chr17_+_8236031 1.478 ENSMUST00000164411.2
Ccr6
chemokine (C-C motif) receptor 6
chr14_+_63436394 1.477 ENSMUST00000121288.1
Fam167a
family with sequence similarity 167, member A
chr13_+_4434306 1.477 ENSMUST00000021630.8
Akr1c6
aldo-keto reductase family 1, member C6
chr13_-_66851513 1.475 ENSMUST00000169322.1
Gm17404
predicted gene, 17404
chr10_-_13388830 1.436 ENSMUST00000079698.5
Phactr2
phosphatase and actin regulator 2
chr15_-_54278420 1.414 ENSMUST00000079772.3
Tnfrsf11b
tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)
chr3_+_57425314 1.410 ENSMUST00000029377.7
Tm4sf4
transmembrane 4 superfamily member 4
chr4_+_44943727 1.367 ENSMUST00000154177.1
Gm12678
predicted gene 12678
chr15_+_9436028 1.355 ENSMUST00000042360.3
Capsl
calcyphosine-like
chr2_-_62483637 1.354 ENSMUST00000136686.1
ENSMUST00000102733.3
Gcg

glucagon

chr11_+_67277124 1.344 ENSMUST00000019625.5
Myh8
myosin, heavy polypeptide 8, skeletal muscle, perinatal
chr3_-_96814518 1.343 ENSMUST00000047702.7
Cd160
CD160 antigen
chr17_-_78684262 1.336 ENSMUST00000145480.1
Strn
striatin, calmodulin binding protein
chr2_-_164221605 1.317 ENSMUST00000018355.4
ENSMUST00000109376.2
Wfdc15b

WAP four-disulfide core domain 15B

chr8_+_109990430 1.313 ENSMUST00000001720.7
ENSMUST00000143741.1
Tat

tyrosine aminotransferase

chr12_-_41485751 1.294 ENSMUST00000043884.4
Lrrn3
leucine rich repeat protein 3, neuronal
chr1_+_131638306 1.282 ENSMUST00000073350.6
Ctse
cathepsin E
chr19_-_39886730 1.279 ENSMUST00000168838.1
Cyp2c69
cytochrome P450, family 2, subfamily c, polypeptide 69
chr6_-_69243445 1.258 ENSMUST00000101325.3
Igkv4-71
immunoglobulin kappa chain variable 4-71
chr9_-_96719404 1.208 ENSMUST00000140121.1
Zbtb38
zinc finger and BTB domain containing 38
chr10_+_127849917 1.197 ENSMUST00000077530.2
Rdh19
retinol dehydrogenase 19
chr2_-_150179679 1.173 ENSMUST00000099418.2
Gm10770
predicted gene 10770
chr13_+_94083490 1.172 ENSMUST00000156071.1
Lhfpl2
lipoma HMGIC fusion partner-like 2
chr6_+_129045893 1.171 ENSMUST00000032257.7
Klrb1f
killer cell lectin-like receptor subfamily B member 1F
chr4_-_134254076 1.151 ENSMUST00000060050.5
Grrp1
glycine/arginine rich protein 1
chr11_+_108920342 1.129 ENSMUST00000052915.7
Axin2
axin2
chr4_+_141420757 1.116 ENSMUST00000102486.4
Hspb7
heat shock protein family, member 7 (cardiovascular)
chr10_-_13388753 1.112 ENSMUST00000105546.1
Phactr2
phosphatase and actin regulator 2
chr9_-_123862023 1.079 ENSMUST00000182350.1
ENSMUST00000078755.2
Xcr1

chemokine (C motif) receptor 1

chrX_-_150812932 1.057 ENSMUST00000131241.1
ENSMUST00000147152.1
ENSMUST00000143843.1
Maged2


melanoma antigen, family D, 2


chr19_+_8591254 1.024 ENSMUST00000010251.3
ENSMUST00000170817.1
Slc22a8

solute carrier family 22 (organic anion transporter), member 8

chr3_+_55242526 0.992 ENSMUST00000054237.7
ENSMUST00000167204.1
Dclk1

doublecortin-like kinase 1

chr8_-_95294074 0.981 ENSMUST00000184103.1
Cngb1
cyclic nucleotide gated channel beta 1
chr7_+_128062657 0.968 ENSMUST00000120355.1
ENSMUST00000106240.2
ENSMUST00000098015.3
Itgam


integrin alpha M


chr14_+_45219993 0.961 ENSMUST00000146150.1
Gpr137c
G protein-coupled receptor 137C
chr1_-_139560158 0.960 ENSMUST00000160423.1
ENSMUST00000023965.5
Cfhr1

complement factor H-related 1

chr9_+_77921908 0.949 ENSMUST00000133757.1
Elovl5
ELOVL family member 5, elongation of long chain fatty acids (yeast)
chr13_+_54701457 0.947 ENSMUST00000037145.7
Cdhr2
cadherin-related family member 2
chr9_+_75232013 0.939 ENSMUST00000036555.6
Myo5c
myosin VC
chr5_-_145879857 0.937 ENSMUST00000035918.7
Cyp3a11
cytochrome P450, family 3, subfamily a, polypeptide 11
chr5_-_87569023 0.917 ENSMUST00000113314.2
Sult1d1
sulfotransferase family 1D, member 1
chr7_-_48558066 0.891 ENSMUST00000052730.1
Mrgprb2
MAS-related GPR, member B2
chr13_-_56548534 0.880 ENSMUST00000062806.4
Lect2
leukocyte cell-derived chemotaxin 2
chr7_-_134225088 0.865 ENSMUST00000067680.4
Adam12
a disintegrin and metallopeptidase domain 12 (meltrin alpha)
chr10_-_115587739 0.861 ENSMUST00000020350.8
Lgr5
leucine rich repeat containing G protein coupled receptor 5
chr9_+_51280295 0.854 ENSMUST00000050829.1
2010007H06Rik
RIKEN cDNA 2010007H06 gene
chr11_-_60036917 0.851 ENSMUST00000102692.3
Pemt
phosphatidylethanolamine N-methyltransferase
chr12_+_24831583 0.832 ENSMUST00000110942.3
ENSMUST00000078902.6
Mboat2

membrane bound O-acyltransferase domain containing 2

chr14_-_45219364 0.831 ENSMUST00000022377.4
ENSMUST00000143609.1
ENSMUST00000139526.1
Txndc16


thioredoxin domain containing 16


chr6_-_87335758 0.807 ENSMUST00000042025.9
Antxr1
anthrax toxin receptor 1
chr10_-_22820126 0.804 ENSMUST00000049930.7
Tcf21
transcription factor 21
chr4_+_95967322 0.803 ENSMUST00000107083.1
Hook1
hook homolog 1 (Drosophila)
chr5_+_99979061 0.789 ENSMUST00000046721.1
4930524J08Rik
RIKEN cDNA 4930524J08 gene
chr17_-_47016956 0.777 ENSMUST00000165525.1
Gm16494
predicted gene 16494
chr14_+_101840501 0.775 ENSMUST00000159026.1
Lmo7
LIM domain only 7
chr16_-_44139630 0.746 ENSMUST00000137557.1
ENSMUST00000147025.1
Atp6v1a

ATPase, H+ transporting, lysosomal V1 subunit A

chrX_-_150812715 0.735 ENSMUST00000112697.3
Maged2
melanoma antigen, family D, 2
chr15_+_102296256 0.724 ENSMUST00000064924.4
Espl1
extra spindle poles-like 1 (S. cerevisiae)
chr13_-_66852017 0.718 ENSMUST00000059329.6
Gm17449
predicted gene, 17449
chr14_+_51114455 0.718 ENSMUST00000100645.3
Eddm3b
epididymal protein 3B
chr10_+_21978643 0.718 ENSMUST00000142174.1
ENSMUST00000164659.1
Sgk1

serum/glucocorticoid regulated kinase 1

chr7_-_47528862 0.716 ENSMUST00000172559.1
Mrgpra2b
MAS-related GPR, member A2B
chr1_+_88095054 0.716 ENSMUST00000150634.1
ENSMUST00000058237.7
Ugt1a7c

UDP glucuronosyltransferase 1 family, polypeptide A7C

chr13_+_47122719 0.709 ENSMUST00000068891.4
Rnf144b
ring finger protein 144B
chr1_+_88087802 0.707 ENSMUST00000113139.1
Ugt1a8
UDP glucuronosyltransferase 1 family, polypeptide A8
chr13_-_41828418 0.704 ENSMUST00000137905.1
Adtrp
androgen dependent TFPI regulating protein
chr3_-_59130610 0.689 ENSMUST00000065220.6
ENSMUST00000091112.4
P2ry14

purinergic receptor P2Y, G-protein coupled, 14

chr3_+_55461758 0.681 ENSMUST00000070418.4
Dclk1
doublecortin-like kinase 1
chr7_-_45211877 0.679 ENSMUST00000033057.7
Dkkl1
dickkopf-like 1
chr19_+_58670358 0.678 ENSMUST00000057270.7
Pnlip
pancreatic lipase
chr7_+_38183787 0.674 ENSMUST00000067854.8
ENSMUST00000177983.1
1600014C10Rik

RIKEN cDNA 1600014C10 gene

chr8_-_86580664 0.673 ENSMUST00000131423.1
ENSMUST00000152438.1
Abcc12

ATP-binding cassette, sub-family C (CFTR/MRP), member 12

chr4_-_19922599 0.668 ENSMUST00000029900.5
Atp6v0d2
ATPase, H+ transporting, lysosomal V0 subunit D2
chr4_+_108479081 0.667 ENSMUST00000155068.1
Zcchc11
zinc finger, CCHC domain containing 11
chr8_+_21665797 0.667 ENSMUST00000075268.4
Gm15315
predicted gene 15315
chr7_+_132859225 0.666 ENSMUST00000084497.5
ENSMUST00000181577.1
ENSMUST00000106161.1
Fam175b


family with sequence similarity 175, member B


chr10_+_115569986 0.657 ENSMUST00000173620.1
A930009A15Rik
RIKEN cDNA A930009A15 gene
chr6_+_117168535 0.640 ENSMUST00000112866.1
ENSMUST00000112871.1
ENSMUST00000073043.4
Cxcl12


chemokine (C-X-C motif) ligand 12


chr1_-_139781236 0.636 ENSMUST00000027612.8
ENSMUST00000111989.2
ENSMUST00000111986.2
Gm4788


predicted gene 4788


chr2_-_91931675 0.635 ENSMUST00000111309.1
Mdk
midkine
chr1_+_172126750 0.635 ENSMUST00000075895.2
ENSMUST00000111252.3
Pex19

peroxisomal biogenesis factor 19

chr1_+_88227005 0.625 ENSMUST00000061013.6
ENSMUST00000113130.1
Mroh2a

maestro heat-like repeat family member 2A

chr11_+_108381164 0.624 ENSMUST00000146050.1
ENSMUST00000152958.1
Apoh

apolipoprotein H

chr4_-_43429071 0.624 ENSMUST00000107929.3
ENSMUST00000107928.2
Fam166b

family with sequence similarity 166, member B

chr13_+_23870284 0.616 ENSMUST00000006785.7
Slc17a1
solute carrier family 17 (sodium phosphate), member 1
chr2_-_91931696 0.616 ENSMUST00000090602.5
Mdk
midkine
chr4_-_142239356 0.613 ENSMUST00000036476.3
Kazn
kazrin, periplakin interacting protein
chr1_+_88070765 0.610 ENSMUST00000073772.4
Ugt1a9
UDP glucuronosyltransferase 1 family, polypeptide A9
chr2_+_157560078 0.607 ENSMUST00000153739.2
ENSMUST00000173595.1
ENSMUST00000109526.1
ENSMUST00000173839.1
ENSMUST00000173041.1
ENSMUST00000173793.1
ENSMUST00000172487.1
ENSMUST00000088484.5
Nnat







neuronatin







chr13_-_62858364 0.603 ENSMUST00000021907.7
Fbp2
fructose bisphosphatase 2
chr1_-_133906973 0.598 ENSMUST00000126123.1
Optc
opticin
chr12_+_38783455 0.597 ENSMUST00000161980.1
ENSMUST00000160701.1
Etv1

ets variant gene 1

chr8_+_21565368 0.595 ENSMUST00000084040.2
Gm14850
predicted gene 14850
chr15_-_78495059 0.594 ENSMUST00000089398.1
Il2rb
interleukin 2 receptor, beta chain
chr12_+_4133394 0.584 ENSMUST00000152065.1
ENSMUST00000127756.1
Adcy3

adenylate cyclase 3

chr1_-_75133866 0.583 ENSMUST00000027405.4
Slc23a3
solute carrier family 23 (nucleobase transporters), member 3
chrY_+_90755657 0.579 ENSMUST00000167967.2
Gm21857
predicted gene, 21857
chr12_+_4133047 0.578 ENSMUST00000124505.1
Adcy3
adenylate cyclase 3
chr13_-_22219820 0.576 ENSMUST00000057516.1
Vmn1r193
vomeronasal 1 receptor 193
chr15_-_66286224 0.571 ENSMUST00000070256.7
Kcnq3
potassium voltage-gated channel, subfamily Q, member 3
chr15_+_10981747 0.564 ENSMUST00000070877.5
Amacr
alpha-methylacyl-CoA racemase
chr10_+_127000709 0.564 ENSMUST00000026500.5
ENSMUST00000142698.1
Avil

advillin

chr8_-_8639363 0.563 ENSMUST00000152698.1
Efnb2
ephrin B2
chr6_+_54267131 0.563 ENSMUST00000114402.2
Chn2
chimerin (chimaerin) 2
chr13_-_107890059 0.557 ENSMUST00000105097.2
Zswim6
zinc finger SWIM-type containing 6
chr1_+_157506728 0.552 ENSMUST00000086130.2
Sec16b
SEC16 homolog B (S. cerevisiae)
chr2_+_70474923 0.542 ENSMUST00000100043.2
Sp5
trans-acting transcription factor 5
chr1_+_157506777 0.541 ENSMUST00000027881.8
Sec16b
SEC16 homolog B (S. cerevisiae)
chr6_+_117559694 0.538 ENSMUST00000162741.1
ENSMUST00000008011.7
Gm9946

predicted gene 9946

chr1_-_168432270 0.536 ENSMUST00000072863.4
Pbx1
pre B cell leukemia homeobox 1
chr1_+_88055467 0.528 ENSMUST00000173325.1
Ugt1a10
UDP glycosyltransferase 1 family, polypeptide A10
chr3_-_15838643 0.525 ENSMUST00000148194.1
Sirpb1c
signal-regulatory protein beta 1C
chr5_-_105239533 0.523 ENSMUST00000065588.6
Gbp10
guanylate-binding protein 10
chr16_+_29210108 0.523 ENSMUST00000162747.1
Hrasls
HRAS-like suppressor
chr5_+_17574268 0.522 ENSMUST00000030568.7
Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr5_+_86071734 0.516 ENSMUST00000031171.7
Stap1
signal transducing adaptor family member 1
chr10_+_38965515 0.514 ENSMUST00000019992.5
Lama4
laminin, alpha 4
chr14_+_54431597 0.511 ENSMUST00000089688.4
Mmp14
matrix metallopeptidase 14 (membrane-inserted)
chr3_+_118562129 0.501 ENSMUST00000039177.7
Dpyd
dihydropyrimidine dehydrogenase
chr4_+_121039385 0.501 ENSMUST00000030372.5
Col9a2
collagen, type IX, alpha 2
chr4_-_43429117 0.497 ENSMUST00000171134.2
ENSMUST00000052829.3
Fam166b

family with sequence similarity 166, member B

chr11_+_96929367 0.495 ENSMUST00000062172.5
Prr15l
proline rich 15-like
chr4_-_16013796 0.479 ENSMUST00000149891.1
Osgin2
oxidative stress induced growth inhibitor family member 2
chr18_+_37400845 0.476 ENSMUST00000057228.1
Pcdhb9
protocadherin beta 9
chr6_+_72629284 0.473 ENSMUST00000156497.1
Gm15401
predicted gene 15401
chr3_-_116712696 0.469 ENSMUST00000169530.1
Slc35a3
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3
chr10_+_69787431 0.463 ENSMUST00000183240.1
Ank3
ankyrin 3, epithelial
chr6_+_86628174 0.462 ENSMUST00000043400.6
Asprv1
aspartic peptidase, retroviral-like 1
chr4_+_45848816 0.462 ENSMUST00000107782.1
ENSMUST00000030011.5
1300002K09Rik

RIKEN cDNA 1300002K09 gene

chr14_+_56017964 0.460 ENSMUST00000022836.4
Mcpt1
mast cell protease 1
chr18_+_44334062 0.457 ENSMUST00000025349.5
ENSMUST00000115498.1
Myot

myotilin

chr8_+_21297439 0.453 ENSMUST00000098892.4
Defa5
defensin, alpha, 5
chr4_-_106727930 0.453 ENSMUST00000106770.1
ENSMUST00000145044.1
Mroh7

maestro heat-like repeat family member 7

chrX_+_169879596 0.450 ENSMUST00000112105.1
ENSMUST00000078947.5
Mid1

midline 1

chr13_+_42301270 0.443 ENSMUST00000021796.7
Edn1
endothelin 1
chr5_-_108795352 0.439 ENSMUST00000004943.1
Tmed11
transmembrane emp24 protein transport domain containing
chr7_+_128062635 0.437 ENSMUST00000064821.7
ENSMUST00000106242.3
Itgam

integrin alpha M

chr8_-_107065632 0.436 ENSMUST00000034393.5
Tmed6
transmembrane emp24 protein transport domain containing 6
chr12_-_87299705 0.433 ENSMUST00000125733.1
Ism2
isthmin 2 homolog (zebrafish)
chr4_+_32238713 0.433 ENSMUST00000108180.2
Bach2
BTB and CNC homology 2
chr1_+_88055377 0.420 ENSMUST00000138182.1
ENSMUST00000113142.3
Ugt1a10

UDP glycosyltransferase 1 family, polypeptide A10

chr6_-_71322200 0.416 ENSMUST00000173297.1
ENSMUST00000114188.2
Smyd1

SET and MYND domain containing 1

chr7_-_3845050 0.411 ENSMUST00000108615.3
ENSMUST00000119469.1
Pira2

paired-Ig-like receptor A2

chr14_+_53665912 0.405 ENSMUST00000181768.1
Trav3-3
T cell receptor alpha variable 3-3
chr9_-_71896047 0.404 ENSMUST00000184448.1
Tcf12
transcription factor 12
chr9_-_98033181 0.403 ENSMUST00000035027.6
Clstn2
calsyntenin 2
chr7_+_140247316 0.391 ENSMUST00000164583.1
ENSMUST00000093984.2
5830411N06Rik

RIKEN cDNA 5830411N06 gene

chr1_+_139454747 0.386 ENSMUST00000053364.8
ENSMUST00000097554.3
Aspm

asp (abnormal spindle)-like, microcephaly associated (Drosophila)

chr17_-_40794063 0.386 ENSMUST00000131699.1
ENSMUST00000024724.7
ENSMUST00000144243.1
Crisp2


cysteine-rich secretory protein 2


chr2_-_35061431 0.385 ENSMUST00000028233.3
Hc
hemolytic complement
chr1_+_171840557 0.385 ENSMUST00000135386.1
Cd84
CD84 antigen
chr11_-_110251736 0.377 ENSMUST00000044003.7
Abca6
ATP-binding cassette, sub-family A (ABC1), member 6
chr4_+_136206365 0.373 ENSMUST00000047526.7
Asap3
ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
chr13_+_45389734 0.370 ENSMUST00000038275.9
Mylip
myosin regulatory light chain interacting protein
chr10_+_89744988 0.370 ENSMUST00000020112.5
Uhrf1bp1l
UHRF1 (ICBP90) binding protein 1-like
chr19_-_40073731 0.367 ENSMUST00000048959.3
Cyp2c54
cytochrome P450, family 2, subfamily c, polypeptide 54

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 6.3 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.8 2.5 GO:0034443 negative regulation of lipoprotein oxidation(GO:0034443) multicellular organismal lipid catabolic process(GO:0044240)
0.8 2.3 GO:2000229 pancreatic stellate cell proliferation(GO:0072343) regulation of pancreatic stellate cell proliferation(GO:2000229)
0.6 8.0 GO:0002002 regulation of angiotensin levels in blood(GO:0002002)
0.6 4.5 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.6 1.7 GO:0072139 glomerular parietal epithelial cell differentiation(GO:0072139)
0.5 1.5 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.4 4.9 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.4 1.5 GO:1902093 positive regulation of flagellated sperm motility(GO:1902093)
0.4 2.9 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.3 1.0 GO:0042939 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.3 0.8 GO:0072275 bronchiole development(GO:0060435) metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.3 1.3 GO:0006572 tyrosine catabolic process(GO:0006572)
0.2 1.7 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.2 0.7 GO:0032685 negative regulation of granulocyte macrophage colony-stimulating factor production(GO:0032685)
0.2 20.7 GO:0070988 demethylation(GO:0070988)
0.2 1.8 GO:0070294 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.2 0.8 GO:0046351 disaccharide biosynthetic process(GO:0046351)
0.2 2.5 GO:0046549 retinal cone cell development(GO:0046549)
0.2 1.2 GO:0008355 olfactory learning(GO:0008355)
0.2 1.4 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.2 0.9 GO:1904970 brush border assembly(GO:1904970)
0.2 0.4 GO:0055098 response to low-density lipoprotein particle stimulus(GO:0055098)
0.2 0.9 GO:0000103 sulfate assimilation(GO:0000103)
0.2 0.9 GO:1905522 negative regulation of macrophage chemotaxis(GO:0010760) negative regulation of macrophage migration(GO:1905522)
0.2 1.3 GO:0030421 defecation(GO:0030421)
0.2 0.9 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.2 0.2 GO:0007521 muscle cell fate determination(GO:0007521)
0.2 0.5 GO:0046104 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859) thymidine metabolic process(GO:0046104)
0.2 0.8 GO:1903054 negative regulation of extracellular matrix organization(GO:1903054)
0.1 0.9 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.1 1.4 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.1 2.0 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.1 0.6 GO:0071352 interleukin-2-mediated signaling pathway(GO:0038110) cellular response to interleukin-2(GO:0071352)
0.1 0.4 GO:0060585 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.1 1.1 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.1 1.0 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.1 0.6 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.1 0.2 GO:0018879 biphenyl metabolic process(GO:0018879)
0.1 3.4 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.1 0.3 GO:0070429 regulation of granuloma formation(GO:0002631) negative regulation of granuloma formation(GO:0002632) regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573)
0.1 0.5 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788)
0.1 0.3 GO:1900368 regulation of RNA interference(GO:1900368)
0.1 0.6 GO:0034196 blood coagulation, intrinsic pathway(GO:0007597) acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.1 1.5 GO:0016540 protein autoprocessing(GO:0016540)
0.1 0.5 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 1.0 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.1 0.6 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.1 1.3 GO:0030049 muscle filament sliding(GO:0030049)
0.1 0.9 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 1.7 GO:0001967 suckling behavior(GO:0001967)
0.1 0.4 GO:0051661 maintenance of centrosome location(GO:0051661)
0.1 0.7 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 0.2 GO:0002355 detection of tumor cell(GO:0002355)
0.1 2.1 GO:0045109 intermediate filament organization(GO:0045109)
0.1 0.6 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849) positive regulation of artery morphogenesis(GO:1905653)
0.1 0.1 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.1 0.6 GO:0008300 isoprenoid catabolic process(GO:0008300)
0.1 0.2 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
0.1 1.2 GO:0032252 secretory granule localization(GO:0032252)
0.1 0.2 GO:1902569 negative regulation of activation of Janus kinase activity(GO:1902569)
0.1 2.0 GO:0048339 paraxial mesoderm development(GO:0048339)
0.1 0.2 GO:1904798 positive regulation of core promoter binding(GO:1904798)
0.1 0.2 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.1 2.9 GO:1901998 toxin transport(GO:1901998)
0.1 0.7 GO:0030299 intestinal cholesterol absorption(GO:0030299)
0.0 0.7 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.7 GO:0000212 meiotic spindle organization(GO:0000212)
0.0 0.2 GO:0072362 regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362)
0.0 0.7 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.1 GO:0050883 regulation of sulfur amino acid metabolic process(GO:0031335) musculoskeletal movement, spinal reflex action(GO:0050883)
0.0 0.5 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.2 GO:0003273 cell migration involved in endocardial cushion formation(GO:0003273) condensed mesenchymal cell proliferation(GO:0072137)
0.0 1.4 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.0 3.9 GO:0051781 positive regulation of cell division(GO:0051781)
0.0 0.3 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.2 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.1 GO:1904457 positive regulation of neuronal action potential(GO:1904457)
0.0 0.5 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.2 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.0 0.2 GO:0051140 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0 0.6 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.4 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 1.7 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.3 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.3 GO:0015961 diadenosine polyphosphate catabolic process(GO:0015961)
0.0 0.5 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.2 GO:0051697 protein delipidation(GO:0051697)
0.0 0.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.1 GO:0070307 lens fiber cell development(GO:0070307)
0.0 5.0 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.5 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.1 GO:1901250 regulation of lung goblet cell differentiation(GO:1901249) negative regulation of lung goblet cell differentiation(GO:1901250)
0.0 0.3 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.0 0.2 GO:0097475 motor neuron migration(GO:0097475)
0.0 2.0 GO:0002228 natural killer cell mediated immunity(GO:0002228)
0.0 0.9 GO:0019731 antibacterial humoral response(GO:0019731)
0.0 0.6 GO:0060081 membrane hyperpolarization(GO:0060081)
0.0 1.7 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.3 GO:0099628 receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
0.0 1.1 GO:0008333 endosome to lysosome transport(GO:0008333)
0.0 1.5 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 1.6 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.7 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.0 0.1 GO:0034651 cortisol biosynthetic process(GO:0034651)
0.0 0.2 GO:0006284 base-excision repair(GO:0006284)
0.0 1.4 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0 2.8 GO:0007586 digestion(GO:0007586)
0.0 0.4 GO:0034391 smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391)
0.0 0.2 GO:0019243 methylglyoxal metabolic process(GO:0009438) methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.5 GO:0030325 adrenal gland development(GO:0030325)
0.0 0.5 GO:0006882 cellular zinc ion homeostasis(GO:0006882) zinc II ion transmembrane transport(GO:0071577)
0.0 1.8 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 2.9 GO:0006275 regulation of DNA replication(GO:0006275)
0.0 0.2 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.4 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.0 0.5 GO:0042832 defense response to protozoan(GO:0042832)
0.0 0.2 GO:1903826 arginine transmembrane transport(GO:1903826)
0.0 0.4 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.1 GO:1903334 positive regulation of protein folding(GO:1903334)
0.0 0.1 GO:1904784 NLRP1 inflammasome complex assembly(GO:1904784)
0.0 0.1 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.3 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.3 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.0 0.3 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.2 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.2 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.0 GO:0045213 neurotransmitter receptor metabolic process(GO:0045213)
0.0 0.1 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) negative regulation of serotonin uptake(GO:0051612)
0.0 0.2 GO:0019441 tryptophan catabolic process(GO:0006569) tryptophan catabolic process to kynurenine(GO:0019441) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218)
0.0 0.1 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.1 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0 0.2 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.0 0.1 GO:1900364 negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364)
0.0 0.2 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.1 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.0 0.5 GO:0051693 actin filament capping(GO:0051693)
0.0 0.3 GO:0015884 folic acid transport(GO:0015884)
0.0 0.4 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.3 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.8 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.6 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.2 GO:0010528 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.0 0.7 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.3 1.7 GO:0071914 prominosome(GO:0071914)
0.2 0.9 GO:0097447 dendritic tree(GO:0097447)
0.2 1.5 GO:0097524 sperm plasma membrane(GO:0097524)
0.2 1.1 GO:0070695 FHF complex(GO:0070695)
0.1 3.1 GO:0042627 chylomicron(GO:0042627)
0.1 0.4 GO:0031088 platelet dense granule membrane(GO:0031088)
0.1 0.9 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.1 0.4 GO:0005594 collagen type IX trimer(GO:0005594)
0.1 0.3 GO:0031074 nucleocytoplasmic transport complex(GO:0031074) nuclear RNA export factor complex(GO:0042272)
0.1 0.3 GO:0044307 dendritic branch(GO:0044307)
0.1 0.4 GO:0036449 microtubule minus-end(GO:0036449)
0.1 0.4 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 0.5 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 0.7 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 1.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 0.8 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 0.4 GO:0005579 membrane attack complex(GO:0005579)
0.1 0.7 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 1.2 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 1.8 GO:0016460 myosin II complex(GO:0016460)
0.0 0.2 GO:1990032 parallel fiber(GO:1990032)
0.0 1.7 GO:0008305 integrin complex(GO:0008305)
0.0 18.6 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.5 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.6 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.2 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 1.3 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 2.2 GO:0005844 polysome(GO:0005844)
0.0 0.2 GO:0030897 HOPS complex(GO:0030897)
0.0 0.9 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 4.4 GO:0072562 blood microparticle(GO:0072562)
0.0 0.2 GO:0030478 actin cap(GO:0030478)
0.0 1.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.2 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.1 GO:0044316 cone cell pedicle(GO:0044316)
0.0 0.9 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.2 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.5 GO:0005605 basal lamina(GO:0005605)
0.0 0.6 GO:0030057 desmosome(GO:0030057)
0.0 1.0 GO:0016235 aggresome(GO:0016235)
0.0 2.4 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 1.7 GO:0031526 brush border membrane(GO:0031526)
0.0 0.2 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 7.3 GO:0030141 secretory granule(GO:0030141)
0.0 0.3 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.0 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.2 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.1 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.7 GO:0042629 mast cell granule(GO:0042629)
0.0 0.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.2 GO:0031143 pseudopodium(GO:0031143)
0.0 0.3 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.1 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.0 0.2 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.0 0.2 GO:0016580 Sin3 complex(GO:0016580)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 20.5 GO:0050649 testosterone 6-beta-hydroxylase activity(GO:0050649)
1.0 7.0 GO:0004027 alcohol sulfotransferase activity(GO:0004027)
0.8 2.3 GO:0023030 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.5 1.5 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.4 1.3 GO:0080130 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.3 6.3 GO:0070411 I-SMAD binding(GO:0070411)
0.3 2.5 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.3 4.5 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
0.2 1.7 GO:0001851 complement component C3b binding(GO:0001851)
0.2 0.6 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.2 0.6 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.2 1.2 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.2 2.5 GO:0050544 arachidonic acid binding(GO:0050544)
0.2 0.9 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.2 0.5 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1 0.8 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.1 3.4 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 0.7 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.1 5.1 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 3.1 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.1 0.6 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 1.4 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.1 0.4 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 3.4 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.1 1.0 GO:0015651 quaternary ammonium group transmembrane transporter activity(GO:0015651)
0.1 1.5 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.1 0.7 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1 0.3 GO:0070401 NADP+ binding(GO:0070401)
0.1 1.9 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.1 0.2 GO:0004461 lactose synthase activity(GO:0004461)
0.1 0.9 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 1.6 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 0.9 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 0.5 GO:0002054 nucleobase binding(GO:0002054)
0.1 0.3 GO:0047710 bis(5'-adenosyl)-triphosphatase activity(GO:0047710)
0.1 3.8 GO:0008146 sulfotransferase activity(GO:0008146)
0.1 0.2 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.1 1.1 GO:0031005 filamin binding(GO:0031005)
0.1 1.3 GO:0042288 MHC class I protein binding(GO:0042288)
0.1 21.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 0.9 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.1 0.3 GO:0004111 creatine kinase activity(GO:0004111)
0.1 0.2 GO:0000700 mismatch base pair DNA N-glycosylase activity(GO:0000700)
0.1 8.6 GO:0008083 growth factor activity(GO:0008083)
0.1 0.5 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.1 0.2 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.1 1.4 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 3.3 GO:0042805 actinin binding(GO:0042805)
0.0 1.3 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.7 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.8 GO:0043855 cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 1.7 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.0 0.3 GO:0070883 pre-miRNA binding(GO:0070883)
0.0 0.6 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 0.3 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 0.5 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.2 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.2 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 0.4 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.2 GO:0004952 dopamine neurotransmitter receptor activity(GO:0004952)
0.0 0.2 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.0 0.3 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 1.5 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.1 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.0 0.2 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.3 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 3.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.7 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.1 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.3 GO:0051870 methotrexate binding(GO:0051870)
0.0 1.0 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.2 GO:0004462 hydroxyacylglutathione hydrolase activity(GO:0004416) lactoylglutathione lyase activity(GO:0004462)
0.0 1.2 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.2 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 0.2 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.3 GO:0038191 neuropilin binding(GO:0038191)
0.0 1.2 GO:0070888 E-box binding(GO:0070888)
0.0 0.2 GO:1901611 phosphatidylglycerol binding(GO:1901611)
0.0 0.5 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.0 0.9 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.5 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) tumor necrosis factor binding(GO:0043120)
0.0 0.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.7 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 2.8 GO:0051015 actin filament binding(GO:0051015)
0.0 0.1 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.2 GO:0004185 serine-type carboxypeptidase activity(GO:0004185) serine-type exopeptidase activity(GO:0070008)
0.0 0.0 GO:0004104 cholinesterase activity(GO:0004104)
0.0 0.1 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.3 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.2 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 3.0 GO:0030246 carbohydrate binding(GO:0030246)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 6.5 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.1 3.0 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 6.4 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 2.3 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.1 2.8 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.1 1.2 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.1 1.7 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.0 0.8 PID_ANTHRAX_PATHWAY Cellular roles of Anthrax toxin
0.0 1.2 PID_ARF6_PATHWAY Arf6 signaling events
0.0 1.3 PID_ER_NONGENOMIC_PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.6 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.0 1.4 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.0 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 0.2 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.0 0.7 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.0 0.6 PID_IL2_PI3K_PATHWAY IL2 signaling events mediated by PI3K
0.0 0.5 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.5 PID_FOXO_PATHWAY FoxO family signaling
0.0 0.4 PID_ENDOTHELIN_PATHWAY Endothelins
0.0 0.6 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.4 ST_TUMOR_NECROSIS_FACTOR_PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.3 ST_GA12_PATHWAY G alpha 12 Pathway
0.0 0.8 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.0 0.4 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 1.2 PID_CMYB_PATHWAY C-MYB transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 REACTOME_BETA_DEFENSINS Genes involved in Beta defensins
0.2 3.2 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.2 4.6 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2 1.5 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.1 0.3 REACTOME_PEPTIDE_HORMONE_BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.1 3.2 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.1 0.5 REACTOME_DEFENSINS Genes involved in Defensins
0.1 1.4 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 1.2 REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 4.0 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 1.0 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 0.7 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.0 1.4 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.0 1.9 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 1.0 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.6 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.9 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.8 REACTOME_ACYL_CHAIN_REMODELLING_OF_PC Genes involved in Acyl chain remodelling of PC
0.0 2.5 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.5 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism
0.0 4.6 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.9 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.0 0.7 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 1.3 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.1 REACTOME_ACTIVATION_OF_NF_KAPPAB_IN_B_CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.2 REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.2 REACTOME_REGULATED_PROTEOLYSIS_OF_P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.2 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.3 REACTOME_UNBLOCKING_OF_NMDA_RECEPTOR_GLUTAMATE_BINDING_AND_ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 1.4 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.6 REACTOME_IL_RECEPTOR_SHC_SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 2.7 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.3 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.7 REACTOME_LIPID_DIGESTION_MOBILIZATION_AND_TRANSPORT Genes involved in Lipid digestion, mobilization, and transport
0.0 0.4 REACTOME_CA_DEPENDENT_EVENTS Genes involved in Ca-dependent events
0.0 0.2 REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.3 REACTOME_MICRORNA_MIRNA_BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.6 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.2 REACTOME_MUSCLE_CONTRACTION Genes involved in Muscle contraction
0.0 0.5 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules