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GSE58827: Dynamics of the Mouse Liver

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Results for Tcf7l1

Z-value: 0.86

Motif logo

Transcription factors associated with Tcf7l1

Gene Symbol Gene ID Gene Info
ENSMUSG00000055799.7 transcription factor 7 like 1 (T cell specific, HMG box)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tcf7l1mm10_v2_chr6_-_72789240_727892620.634.4e-05Click!

Activity profile of Tcf7l1 motif

Sorted Z-values of Tcf7l1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_173021902 4.03 ENSMUST00000029014.9
RNA binding motif protein 38
chr12_+_24831583 3.74 ENSMUST00000110942.3
ENSMUST00000078902.6
membrane bound O-acyltransferase domain containing 2
chr9_+_98490522 3.71 ENSMUST00000035029.2
retinol binding protein 2, cellular
chr4_+_115057683 3.64 ENSMUST00000161601.1
T cell acute lymphocytic leukemia 1
chr18_+_21072329 3.64 ENSMUST00000082235.4
meprin 1 beta
chr5_-_148392810 3.63 ENSMUST00000138257.1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr10_+_43579161 3.52 ENSMUST00000058714.8
CD24a antigen
chr2_+_173022360 3.41 ENSMUST00000173997.1
RNA binding motif protein 38
chr5_-_122050102 3.16 ENSMUST00000154139.1
cut-like homeobox 2
chr7_+_45216671 2.99 ENSMUST00000134420.1
TEA domain family member 2
chr2_+_157560078 2.98 ENSMUST00000153739.2
ENSMUST00000173595.1
ENSMUST00000109526.1
ENSMUST00000173839.1
ENSMUST00000173041.1
ENSMUST00000173793.1
ENSMUST00000172487.1
ENSMUST00000088484.5
neuronatin
chr5_+_44100442 2.87 ENSMUST00000072800.4
predicted gene 16401
chr6_+_86628174 2.84 ENSMUST00000043400.6
aspartic peptidase, retroviral-like 1
chr8_+_79028587 2.77 ENSMUST00000119254.1
zinc finger protein 827
chr19_+_8591254 2.75 ENSMUST00000010251.3
ENSMUST00000170817.1
solute carrier family 22 (organic anion transporter), member 8
chr1_+_136467958 2.46 ENSMUST00000047817.6
kinesin family member 14
chr8_-_4259257 2.46 ENSMUST00000053252.7
cortexin 1
chr19_-_41802028 2.31 ENSMUST00000026150.8
ENSMUST00000177495.1
ENSMUST00000163265.1
Rho GTPase activating protein 19
chr11_-_87108656 2.26 ENSMUST00000051395.8
proline rich 11
chr10_-_116473875 2.17 ENSMUST00000068233.4
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chrX_-_150812932 2.14 ENSMUST00000131241.1
ENSMUST00000147152.1
ENSMUST00000143843.1
melanoma antigen, family D, 2
chr4_+_11758147 2.13 ENSMUST00000029871.5
ENSMUST00000108303.1
cadherin 17
chrX_-_150812715 2.04 ENSMUST00000112697.3
melanoma antigen, family D, 2
chr6_-_83527452 1.97 ENSMUST00000141904.1
actin, gamma 2, smooth muscle, enteric
chr7_-_142095266 1.93 ENSMUST00000039926.3
dual specificity phosphatase 8
chr8_-_85386310 1.91 ENSMUST00000137290.1
myosin light chain kinase 3
chr8_+_79028317 1.84 ENSMUST00000087927.4
ENSMUST00000098614.2
zinc finger protein 827
chr1_-_182019927 1.77 ENSMUST00000078719.6
ENSMUST00000111030.3
ENSMUST00000177811.1
ENSMUST00000111024.3
ENSMUST00000111025.2
enabled homolog (Drosophila)
chr7_+_100493795 1.74 ENSMUST00000129324.1
uncoupling protein 2 (mitochondrial, proton carrier)
chr19_-_46327121 1.66 ENSMUST00000041391.4
ENSMUST00000096029.5
pleckstrin and Sec7 domain containing
chr17_+_34604262 1.63 ENSMUST00000174041.1
1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)
chr2_+_121357714 1.62 ENSMUST00000125812.1
ENSMUST00000078222.2
ENSMUST00000125221.1
ENSMUST00000150271.1
creatine kinase, mitochondrial 1, ubiquitous
chr4_-_43483696 1.59 ENSMUST00000030180.6
suppression inducing transmembrane adaptor 1
chr7_-_13009795 1.54 ENSMUST00000051390.7
ENSMUST00000172240.1
zinc finger and BTB domain containing 45
chr7_-_83884289 1.53 ENSMUST00000094216.3
mesoderm development candidate 1
chr11_+_96929367 1.49 ENSMUST00000062172.5
proline rich 15-like
chr5_-_134946917 1.49 ENSMUST00000051401.2
claudin 4
chr3_-_50443603 1.43 ENSMUST00000029297.4
solute carrier family 7 (cationic amino acid transporter, y+ system), member 11
chr4_+_107802277 1.40 ENSMUST00000106733.2
ENSMUST00000030356.3
ENSMUST00000106732.2
ENSMUST00000126573.1
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
chr15_-_98482683 1.39 ENSMUST00000023726.3
lactalbumin, alpha
chr2_+_174760619 1.39 ENSMUST00000029030.2
endothelin 3
chr7_+_98835104 1.37 ENSMUST00000165122.1
ENSMUST00000067495.2
wingless-related MMTV integration site 11
chr11_+_46055973 1.35 ENSMUST00000011400.7
a disintegrin and metallopeptidase domain 19 (meltrin beta)
chr8_+_86745679 1.32 ENSMUST00000098532.2
predicted gene 10638
chr6_+_17065129 1.30 ENSMUST00000115467.4
ENSMUST00000154266.2
ENSMUST00000076654.7
testis derived transcript
chr5_+_37242025 1.28 ENSMUST00000114158.2
collapsin response mediator protein 1
chr6_-_52234902 1.27 ENSMUST00000125581.1
homeobox A10
chr1_-_183147461 1.26 ENSMUST00000171366.1
dispatched homolog 1 (Drosophila)
chrX_+_164140447 1.24 ENSMUST00000073973.4
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
chr5_-_131538687 1.24 ENSMUST00000161374.1
autism susceptibility candidate 2
chr11_+_67200052 1.24 ENSMUST00000124516.1
ENSMUST00000018637.8
myosin, heavy polypeptide 1, skeletal muscle, adult
chr5_+_33983437 1.23 ENSMUST00000114384.1
ENSMUST00000094869.5
ENSMUST00000114383.1
predicted gene 1673
chr9_+_119444923 1.20 ENSMUST00000035094.6
ENSMUST00000164213.2
endo/exonuclease (5'-3'), endonuclease G-like
chr2_+_26315513 1.19 ENSMUST00000066936.2
ENSMUST00000078616.5
G-protein signalling modulator 1 (AGS3-like, C. elegans)
chr9_-_103761820 1.18 ENSMUST00000049452.8
transmembrane protein 108
chr5_+_33983534 1.18 ENSMUST00000114382.1
predicted gene 1673
chr11_-_61719946 1.17 ENSMUST00000151780.1
ENSMUST00000148584.1
solute carrier family 5 (sodium/glucose cotransporter), member 10
chr13_+_21945084 1.16 ENSMUST00000176511.1
ENSMUST00000102978.1
ENSMUST00000152258.2
zinc finger protein 184 (Kruppel-like)
chr12_-_16800674 1.16 ENSMUST00000162112.1
gene regulated by estrogen in breast cancer protein
chr11_+_96929260 1.12 ENSMUST00000054311.5
ENSMUST00000107636.3
proline rich 15-like
chrX_+_6415736 1.11 ENSMUST00000143641.3
shroom family member 4
chr2_+_174760781 1.10 ENSMUST00000140908.1
endothelin 3
chr14_-_98169542 1.09 ENSMUST00000069334.7
ENSMUST00000071533.6
dachshund 1 (Drosophila)
chr3_+_131110350 1.07 ENSMUST00000066849.6
ENSMUST00000106341.2
ENSMUST00000029611.7
lymphoid enhancer binding factor 1
chr17_+_12119274 1.06 ENSMUST00000024594.2
1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta)
chr12_+_81631369 1.06 ENSMUST00000036116.5
tetratricopeptide repeat domain 9
chr5_+_31193227 1.06 ENSMUST00000031029.8
ENSMUST00000133711.1
ENSMUST00000132471.1
sorting nexin 17
chr19_-_47919269 1.06 ENSMUST00000095998.5
inositol 1,4,5-triphosphate receptor interacting protein
chr4_+_127172866 1.06 ENSMUST00000106094.2
discs, large (Drosophila) homolog-associated protein 3
chr6_-_148944750 1.01 ENSMUST00000111562.1
ENSMUST00000081956.5
family with sequence similarity 60, member A
chr8_+_70493156 0.99 ENSMUST00000008032.7
cytokine receptor-like factor 1
chrX_+_37048807 0.98 ENSMUST00000060057.1
sosondowah ankyrin repeat domain family member D
chr4_+_141420757 0.98 ENSMUST00000102486.4
heat shock protein family, member 7 (cardiovascular)
chr17_+_47726834 0.97 ENSMUST00000024782.5
ENSMUST00000144955.1
progastricsin (pepsinogen C)
chrX_-_48034842 0.95 ENSMUST00000039026.7
apelin
chr14_+_70774304 0.93 ENSMUST00000022698.7
docking protein 2
chr11_+_69846610 0.93 ENSMUST00000152566.1
ENSMUST00000108633.2
phospholipid scramblase 3
chr9_-_65580040 0.93 ENSMUST00000068944.7
pleckstrin homology domain containing, family O member 2
chr15_-_98953541 0.92 ENSMUST00000097014.5
tubulin, alpha 1A
chr17_+_28530834 0.91 ENSMUST00000025060.2
armadillo repeat containing 12
chr14_-_70766598 0.91 ENSMUST00000167242.1
ENSMUST00000022696.6
exportin 7
chr14_+_51114455 0.90 ENSMUST00000100645.3
epididymal protein 3B
chr17_+_7925990 0.88 ENSMUST00000036370.7
T cell activation Rho GTPase activating protein
chr6_+_29735667 0.88 ENSMUST00000001812.4
smoothened homolog (Drosophila)
chr4_+_127021311 0.88 ENSMUST00000030623.7
splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)
chr14_+_65605267 0.87 ENSMUST00000079469.6
nuclear GTPase, germinal center associated
chr2_-_35432552 0.87 ENSMUST00000079424.4
glycoprotein galactosyltransferase alpha 1, 3
chr13_-_55488038 0.86 ENSMUST00000109921.2
ENSMUST00000109923.2
ENSMUST00000021950.8
drebrin 1
chr6_-_122340499 0.85 ENSMUST00000160843.1
polyhomeotic-like 1 (Drosophila)
chr19_-_5894100 0.84 ENSMUST00000055911.4
tigger transposable element derived 3
chr11_+_69846665 0.84 ENSMUST00000019605.2
phospholipid scramblase 3
chr11_+_5861886 0.84 ENSMUST00000102923.3
AE binding protein 1
chr6_-_122340525 0.83 ENSMUST00000112600.2
polyhomeotic-like 1 (Drosophila)
chr6_-_52240841 0.83 ENSMUST00000121043.1
homeobox A10
chr19_-_46338632 0.82 ENSMUST00000051234.8
ENSMUST00000167861.1
CUE domain containing 2
chr12_-_84148449 0.82 ENSMUST00000061425.2
paraneoplastic antigen MA1
chr2_+_4559742 0.79 ENSMUST00000176828.1
FERM domain containing 4A
chr11_-_87074055 0.78 ENSMUST00000020804.7
glycerophosphodiester phosphodiesterase domain containing 1
chr15_-_50889691 0.77 ENSMUST00000165201.2
ENSMUST00000184458.1
trichorhinophalangeal syndrome I (human)
chr8_-_69184177 0.77 ENSMUST00000185176.1
leucine zipper, putative tumor suppressor 1
chr6_+_38918969 0.77 ENSMUST00000003017.6
thromboxane A synthase 1, platelet
chr6_+_83057844 0.76 ENSMUST00000077502.2
DEAQ RNA-dependent ATPase
chr10_+_79988584 0.75 ENSMUST00000004784.4
ENSMUST00000105374.1
calponin 2
chr14_-_70176787 0.75 ENSMUST00000153735.1
PDZ and LIM domain 2
chr11_+_69846374 0.74 ENSMUST00000108632.1
phospholipid scramblase 3
chr17_-_51810866 0.73 ENSMUST00000176669.1
special AT-rich sequence binding protein 1
chr4_-_141599835 0.73 ENSMUST00000141518.1
ENSMUST00000127455.1
ENSMUST00000105784.1
ENSMUST00000147785.1
filamin binding LIM protein 1
chr5_-_5266038 0.72 ENSMUST00000115451.1
ENSMUST00000115452.1
ENSMUST00000131392.1
cyclin-dependent kinase 14
chr17_-_46202576 0.72 ENSMUST00000024749.7
polymerase (DNA directed), eta (RAD 30 related)
chr19_-_32466575 0.71 ENSMUST00000078034.3
ribosomal protein L9, pseudogene 6
chr12_+_31265234 0.71 ENSMUST00000169088.1
laminin B1
chr7_-_115824699 0.70 ENSMUST00000169129.1
SRY-box containing gene 6
chr11_-_54068932 0.70 ENSMUST00000093109.4
ENSMUST00000018755.3
PDZ and LIM domain 4
chr11_+_46404720 0.70 ENSMUST00000063166.5
family with sequence similarity 71, member B
chr8_-_85067982 0.69 ENSMUST00000177563.1
predicted gene 5741
chr11_+_3330781 0.69 ENSMUST00000136536.1
ENSMUST00000093399.4
phosphoinositide-3-kinase interacting protein 1
chr2_+_163658370 0.69 ENSMUST00000164399.1
ENSMUST00000064703.6
ENSMUST00000099105.2
ENSMUST00000152418.1
ENSMUST00000126182.1
ENSMUST00000131228.1
protein kinase inhibitor, gamma
chr12_+_31265279 0.68 ENSMUST00000002979.8
ENSMUST00000170495.1
laminin B1
chr14_+_54936456 0.68 ENSMUST00000037814.6
CKLF-like MARVEL transmembrane domain containing 5
chr5_-_134552414 0.68 ENSMUST00000100647.2
ENSMUST00000036999.6
CAP-GLY domain containing linker protein 2
chr18_-_61036189 0.68 ENSMUST00000025521.8
caudal type homeobox 1
chr4_+_107367757 0.64 ENSMUST00000139560.1
NDC1 transmembrane nucleoporin
chr4_+_129906205 0.63 ENSMUST00000145196.1
ENSMUST00000141731.1
ENSMUST00000129149.1
RIKEN cDNA E330017L17 gene
chr9_+_21616166 0.62 ENSMUST00000034707.8
ENSMUST00000098948.3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
chr2_+_167932327 0.62 ENSMUST00000029053.7
protein tyrosine phosphatase, non-receptor type 1
chrX_-_57393020 0.62 ENSMUST00000143310.1
ENSMUST00000098470.2
ENSMUST00000114726.1
RNA binding motif protein, X chromosome
chr1_+_87470258 0.62 ENSMUST00000027476.4
RIKEN cDNA 3110079O15 gene
chr17_-_47924460 0.61 ENSMUST00000113262.1
forkhead box P4
chr3_-_25212720 0.58 ENSMUST00000091289.3
predicted pseudogene 10259
chr8_+_31111816 0.58 ENSMUST00000046941.7
ring finger protein 122
chr1_-_36683115 0.57 ENSMUST00000170295.1
ENSMUST00000114981.1
family with sequence similarity 178, member B
chr10_-_22731336 0.56 ENSMUST00000127698.1
TATA box binding protein-like 1
chr10_-_52195244 0.55 ENSMUST00000020045.3
Ros1 proto-oncogene
chr17_-_47924400 0.54 ENSMUST00000113263.1
ENSMUST00000097311.2
forkhead box P4
chrX_-_167209149 0.54 ENSMUST00000112176.1
thymosin, beta 4, X chromosome
chr16_+_19760902 0.53 ENSMUST00000119468.1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr14_+_119138415 0.53 ENSMUST00000065904.3
heparan sulfate 6-O-sulfotransferase 3
chr12_+_21417872 0.52 ENSMUST00000180671.1
predicted gene 4419
chr3_+_32708546 0.52 ENSMUST00000029214.7
actin-like 6A
chr1_+_110099295 0.52 ENSMUST00000134301.1
cadherin 7, type 2
chr17_+_75005523 0.51 ENSMUST00000001927.5
latent transforming growth factor beta binding protein 1
chr4_+_132638987 0.50 ENSMUST00000135299.1
ENSMUST00000081726.6
ENSMUST00000180250.1
ENSMUST00000020197.7
ENSMUST00000079157.4
eyes absent 3 homolog (Drosophila)
chr4_-_94650092 0.49 ENSMUST00000107101.1
leucine rich repeat containing 19
chr11_+_3649759 0.49 ENSMUST00000140242.1
microrchidia 2A
chr12_+_84996309 0.49 ENSMUST00000168977.1
ENSMUST00000021670.8
YLP motif containing 1
chr6_-_47594967 0.48 ENSMUST00000081721.6
ENSMUST00000114618.1
ENSMUST00000114616.1
enhancer of zeste homolog 2 (Drosophila)
chr13_+_94083490 0.48 ENSMUST00000156071.1
lipoma HMGIC fusion partner-like 2
chr4_-_129742275 0.47 ENSMUST00000066257.5
KH domain containing, RNA binding, signal transduction associated 1
chr12_+_53248677 0.46 ENSMUST00000101432.2
neuronal PAS domain protein 3
chr2_+_157087042 0.45 ENSMUST00000166140.1
TBC/LysM associated domain containing 2
chr9_+_35423582 0.44 ENSMUST00000154652.1
cell adhesion molecule-related/down-regulated by oncogenes
chr17_-_35697971 0.44 ENSMUST00000146472.1
discoidin domain receptor family, member 1
chr4_+_85205120 0.43 ENSMUST00000107188.3
SH3-domain GRB2-like 2
chr17_-_89910449 0.43 ENSMUST00000086423.4
predicted pseudogene 10184
chr7_+_73375494 0.43 ENSMUST00000094312.5
ENSMUST00000119206.1
RGM domain family, member A
chr12_-_24096968 0.42 ENSMUST00000101538.3
RIKEN cDNA 9030624G23 gene
chr8_-_122678072 0.42 ENSMUST00000006525.7
ENSMUST00000064674.6
core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)
chr2_+_124610573 0.42 ENSMUST00000103239.3
ENSMUST00000103240.2
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr5_-_147307264 0.42 ENSMUST00000031650.3
caudal type homeobox 2
chr4_+_62583568 0.41 ENSMUST00000098031.3
regulator of G-protein signaling 3
chr18_+_82914632 0.41 ENSMUST00000071233.6
zinc finger protein 516
chr14_-_101729690 0.40 ENSMUST00000066461.3
predicted gene 9922
chr9_+_72925622 0.40 ENSMUST00000038489.5
pygopus 1
chr12_+_84996487 0.40 ENSMUST00000101202.3
YLP motif containing 1
chr10_+_53596936 0.39 ENSMUST00000020004.6
ASF1 anti-silencing function 1 homolog A (S. cerevisiae)
chr12_-_54986363 0.39 ENSMUST00000173433.1
ENSMUST00000173803.1
bromodomain adjacent to zinc finger domain 1A
predicted gene 20403
chr11_+_96316684 0.38 ENSMUST00000049241.7
homeobox B4
chr9_-_45984816 0.37 ENSMUST00000172450.1
platelet-activating factor acetylhydrolase, isoform 1b, subunit 2
chrX_+_169879596 0.37 ENSMUST00000112105.1
ENSMUST00000078947.5
midline 1
chr1_-_78968079 0.36 ENSMUST00000049117.5
predicted pseudogene 5830
chr10_-_13388830 0.35 ENSMUST00000079698.5
phosphatase and actin regulator 2
chrX_-_7572843 0.35 ENSMUST00000132788.1
protein phosphatase 1, regulatory (inhibitor) subunit 3F
chr13_-_97747399 0.35 ENSMUST00000144993.1
RIKEN cDNA 5330416C01 gene
chr1_-_45925570 0.34 ENSMUST00000027137.4
solute carrier family 40 (iron-regulated transporter), member 1
chr15_+_102990576 0.34 ENSMUST00000001703.6
homeobox C8
chr4_-_142239356 0.33 ENSMUST00000036476.3
kazrin, periplakin interacting protein
chr6_-_52218686 0.33 ENSMUST00000134367.2
homeobox A7
chr14_-_93888732 0.33 ENSMUST00000068992.2
protocadherin 9
chrX_+_71556874 0.32 ENSMUST00000123100.1
high mobility group box 3
chr3_+_53463666 0.32 ENSMUST00000058577.4
proline and serine rich 1
chr6_+_6248659 0.32 ENSMUST00000181633.1
ENSMUST00000176283.1
ENSMUST00000175814.1
ENSMUST00000181192.1
predicted gene 20619
chr5_-_114380505 0.31 ENSMUST00000102581.4
potassium channel tetramerisation domain containing 10
chr17_+_46202740 0.31 ENSMUST00000087031.5
exportin 5
chr10_-_13388753 0.31 ENSMUST00000105546.1
phosphatase and actin regulator 2
chr7_-_27196138 0.31 ENSMUST00000122202.1
ENSMUST00000080356.3
small nuclear ribonucleoprotein polypeptide A
chr10_-_52194956 0.30 ENSMUST00000117992.2
Ros1 proto-oncogene
chr2_-_165034770 0.29 ENSMUST00000122070.1
ENSMUST00000121377.1
nuclear receptor coactivator 5
chr17_-_68004075 0.29 ENSMUST00000024840.5
Rho GTPase activating protein 28
chr6_-_3498297 0.28 ENSMUST00000183736.1
HEPACAM family member 2
chr6_+_83137089 0.28 ENSMUST00000121093.1
ENSMUST00000087938.4
rhotekin
chr2_-_165034821 0.27 ENSMUST00000153905.1
ENSMUST00000040381.8
nuclear receptor coactivator 5
chr2_+_37516618 0.27 ENSMUST00000065441.6
G protein-coupled receptor 21
chr4_+_48585135 0.27 ENSMUST00000030032.6
transmembrane protein with EGF-like and two follistatin-like domains 1
chr2_-_69586021 0.27 ENSMUST00000100051.2
ENSMUST00000092551.4
ENSMUST00000080953.5
low density lipoprotein receptor-related protein 2
chr10_+_11609256 0.27 ENSMUST00000052902.7
predicted pseudogene 9797
chr13_-_41358990 0.27 ENSMUST00000163623.1
neural precursor cell expressed, developmentally down-regulated gene 9
chrX_-_57392962 0.26 ENSMUST00000114730.1
RNA binding motif protein, X chromosome
chr12_-_41485751 0.26 ENSMUST00000043884.4
leucine rich repeat protein 3, neuronal
chr1_-_86111970 0.26 ENSMUST00000027431.6
5-hydroxytryptamine (serotonin) receptor 2B
chr4_+_108479081 0.25 ENSMUST00000155068.1
zinc finger, CCHC domain containing 11

Network of associatons between targets according to the STRING database.

First level regulatory network of Tcf7l1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.6 GO:0060217 hemangioblast cell differentiation(GO:0060217)
1.2 3.5 GO:0002842 positive regulation of T cell mediated immune response to tumor cell(GO:0002842)
0.9 2.7 GO:0034635 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.8 2.5 GO:0033624 negative regulation of integrin activation(GO:0033624)
0.7 2.1 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.6 7.4 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.5 4.2 GO:0070294 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.5 3.7 GO:0006776 vitamin A metabolic process(GO:0006776)
0.4 2.5 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100) vein smooth muscle contraction(GO:0014826)
0.4 1.2 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.3 1.4 GO:0046351 disaccharide biosynthetic process(GO:0046351)
0.3 1.4 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.3 1.4 GO:0060031 mediolateral intercalation(GO:0060031) planar cell polarity pathway involved in gastrula mediolateral intercalation(GO:0060775)
0.3 1.3 GO:1904616 regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
0.3 1.9 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.3 0.9 GO:0043396 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) positive regulation of corticotropin-releasing hormone secretion(GO:0051466) regulation of G-protein coupled receptor internalization(GO:1904020)
0.3 1.2 GO:0015827 aromatic amino acid transport(GO:0015801) tryptophan transport(GO:0015827)
0.3 0.9 GO:0007494 midgut development(GO:0007494)
0.3 0.9 GO:0010643 cell communication by chemical coupling(GO:0010643) negative regulation of locomotion involved in locomotory behavior(GO:0090327)
0.3 1.1 GO:0071899 negative regulation of interleukin-13 production(GO:0032696) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
0.2 0.7 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.2 3.6 GO:0015809 arginine transport(GO:0015809)
0.2 1.1 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.2 0.9 GO:0033575 protein glycosylation at cell surface(GO:0033575) protein galactosylation at cell surface(GO:0033580) protein galactosylation(GO:0042125)
0.2 1.6 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.2 1.9 GO:0005513 detection of calcium ion(GO:0005513)
0.2 0.8 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.2 1.0 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.2 0.5 GO:0071707 immunoglobulin heavy chain V-D-J recombination(GO:0071707)
0.2 0.5 GO:0032241 positive regulation of nucleobase-containing compound transport(GO:0032241)
0.2 0.6 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202) negative regulation of PERK-mediated unfolded protein response(GO:1903898)
0.1 1.2 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 0.9 GO:0010966 regulation of phosphate transport(GO:0010966)
0.1 0.6 GO:0009212 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) dTTP metabolic process(GO:0046075)
0.1 0.7 GO:0002225 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.1 3.2 GO:0007614 short-term memory(GO:0007614)
0.1 1.4 GO:0089711 L-glutamate transmembrane transport(GO:0089711) L-alpha-amino acid transmembrane transport(GO:1902475)
0.1 0.9 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.1 0.6 GO:0007403 glial cell fate determination(GO:0007403)
0.1 0.7 GO:0071494 cellular response to UV-C(GO:0071494)
0.1 1.6 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.1 0.3 GO:0034395 regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
0.1 2.7 GO:0048368 lateral mesoderm development(GO:0048368)
0.1 1.2 GO:1901250 regulation of lung goblet cell differentiation(GO:1901249) negative regulation of lung goblet cell differentiation(GO:1901250)
0.1 1.7 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1 0.8 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.1 1.9 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 1.3 GO:0060539 diaphragm development(GO:0060539)
0.1 0.5 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.3 GO:0007208 phospholipase C-activating serotonin receptor signaling pathway(GO:0007208)
0.1 1.1 GO:0014807 regulation of somitogenesis(GO:0014807)
0.1 1.2 GO:1904659 glucose transmembrane transport(GO:1904659)
0.1 0.3 GO:1900368 regulation of RNA interference(GO:1900368)
0.1 0.9 GO:0016446 somatic diversification of immune receptors via somatic mutation(GO:0002566) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.1 0.3 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.1 3.7 GO:1901998 toxin transport(GO:1901998)
0.1 1.5 GO:0061436 establishment of skin barrier(GO:0061436)
0.1 0.3 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.1 0.7 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.1 0.5 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 0.7 GO:0033623 regulation of integrin activation(GO:0033623)
0.1 2.1 GO:0060065 uterus development(GO:0060065)
0.1 1.7 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 0.4 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.1 0.5 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.6 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.0 2.7 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.4 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.0 0.2 GO:0030576 Cajal body organization(GO:0030576)
0.0 0.4 GO:0048539 bone marrow development(GO:0048539)
0.0 1.1 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.7 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.4 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.4 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.1 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.0 0.2 GO:0035280 miRNA loading onto RISC involved in gene silencing by miRNA(GO:0035280)
0.0 0.7 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.8 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 0.3 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.0 0.2 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.0 0.2 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934) positive regulation of cytoplasmic translation(GO:2000767)
0.0 3.0 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.0 0.8 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 1.5 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 1.6 GO:0043029 T cell homeostasis(GO:0043029)
0.0 2.5 GO:0055092 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.0 0.0 GO:0060983 epicardium-derived cardiac vascular smooth muscle cell differentiation(GO:0060983)
0.0 0.3 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.5 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 1.1 GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.0 0.8 GO:0034308 primary alcohol metabolic process(GO:0034308)
0.0 0.3 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465)
0.0 4.7 GO:0008654 phospholipid biosynthetic process(GO:0008654)
0.0 0.8 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.2 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.5 GO:0042711 maternal behavior(GO:0042711)
0.0 0.4 GO:1903204 negative regulation of oxidative stress-induced neuron death(GO:1903204)
0.0 0.2 GO:0071233 response to leucine(GO:0043201) cellular response to leucine(GO:0071233)
0.0 0.1 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.0 0.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.4 GO:0007289 spermatid nucleus differentiation(GO:0007289)
0.0 0.8 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.0 0.8 GO:0002437 inflammatory response to antigenic stimulus(GO:0002437)
0.0 2.2 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.3 GO:0045056 transcytosis(GO:0045056)
0.0 0.9 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.1 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.5 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 3.7 GO:0016485 protein processing(GO:0016485)
0.0 1.1 GO:0032091 negative regulation of protein binding(GO:0032091)
0.0 0.4 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.3 GO:0031424 keratinization(GO:0031424)
0.0 0.4 GO:0009409 response to cold(GO:0009409)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.6 GO:0033193 Lsd1/2 complex(GO:0033193)
1.0 3.0 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.5 1.4 GO:0005607 laminin-2 complex(GO:0005607)
0.2 1.0 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.2 0.9 GO:1902737 dendritic filopodium(GO:1902737)
0.2 0.5 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.2 1.6 GO:0001739 sex chromatin(GO:0001739)
0.1 0.9 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 0.7 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1 3.2 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 0.8 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 0.9 GO:0042382 paraspeckles(GO:0042382)
0.1 1.1 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.1 0.3 GO:0042272 nucleocytoplasmic shuttling complex(GO:0031074) nuclear RNA export factor complex(GO:0042272)
0.1 0.6 GO:0097443 sorting endosome(GO:0097443)
0.1 0.4 GO:0008623 CHRAC(GO:0008623)
0.1 0.6 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.1 0.2 GO:0030905 retromer, tubulation complex(GO:0030905)
0.1 0.9 GO:0044294 dendritic growth cone(GO:0044294)
0.1 0.2 GO:0044094 host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094)
0.1 2.5 GO:0051233 spindle midzone(GO:0051233)
0.1 1.5 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 1.1 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 2.1 GO:0016460 myosin II complex(GO:0016460)
0.0 1.0 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.2 GO:1990032 parallel fiber(GO:1990032)
0.0 0.1 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.0 0.5 GO:0031011 Ino80 complex(GO:0031011)
0.0 0.2 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 1.7 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.5 GO:0036038 MKS complex(GO:0036038)
0.0 0.6 GO:0042599 lamellar body(GO:0042599)
0.0 0.2 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.2 GO:0005638 lamin filament(GO:0005638)
0.0 0.5 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.5 GO:0045120 pronucleus(GO:0045120)
0.0 1.8 GO:0030175 filopodium(GO:0030175)
0.0 1.9 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 5.7 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.9 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.9 GO:0031985 Golgi cisterna(GO:0031985)
0.0 1.6 GO:0030496 midbody(GO:0030496)
0.0 1.3 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 1.1 GO:0005901 caveola(GO:0005901)
0.0 0.4 GO:0001533 cornified envelope(GO:0001533)
0.0 1.6 GO:0043204 perikaryon(GO:0043204)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.6 3.7 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.6 2.5 GO:0031708 endothelin B receptor binding(GO:0031708)
0.5 1.4 GO:0004461 lactose synthase activity(GO:0004461)
0.5 3.6 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.4 1.4 GO:0038025 reelin receptor activity(GO:0038025)
0.3 1.7 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.3 2.7 GO:0015651 quaternary ammonium group transmembrane transporter activity(GO:0015651)
0.3 1.9 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.3 1.6 GO:0004111 creatine kinase activity(GO:0004111)
0.3 3.7 GO:0016918 retinal binding(GO:0016918) retinol binding(GO:0019841)
0.2 1.4 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.2 3.5 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.2 2.6 GO:0005522 profilin binding(GO:0005522)
0.2 1.2 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.2 0.5 GO:0008457 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.2 0.7 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.2 0.5 GO:0050436 microfibril binding(GO:0050436)
0.2 1.4 GO:0043208 glycosphingolipid binding(GO:0043208)
0.2 1.1 GO:0030284 estrogen receptor activity(GO:0030284)
0.1 3.7 GO:0031005 filamin binding(GO:0031005)
0.1 0.9 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.1 1.1 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1 3.8 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.1 2.7 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 0.5 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.1 1.9 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.9 GO:0005113 patched binding(GO:0005113)
0.1 0.4 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.1 1.0 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.1 1.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 2.5 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.1 0.5 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.1 2.5 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 1.2 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 1.3 GO:0015197 peptide transporter activity(GO:0015197)
0.1 0.3 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.1 0.3 GO:2001069 glycogen binding(GO:2001069)
0.1 1.9 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 7.4 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.1 2.5 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 0.9 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 0.3 GO:0004952 dopamine neurotransmitter receptor activity(GO:0004952)
0.1 0.5 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.1 1.2 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.1 0.8 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 0.3 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.1 0.2 GO:1990460 leptin receptor binding(GO:1990460)
0.1 0.2 GO:0033680 ATP-dependent DNA/RNA helicase activity(GO:0033680)
0.1 3.0 GO:0070888 E-box binding(GO:0070888)
0.0 1.2 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 1.7 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.4 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.6 GO:0001164 RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 0.4 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 0.7 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.8 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.3 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.7 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.9 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 1.6 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.2 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.6 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.5 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.7 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 2.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.2 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.3 GO:0051378 serotonin binding(GO:0051378)
0.0 0.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.2 GO:0035198 miRNA binding(GO:0035198)
0.0 1.1 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.8 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 1.4 GO:0030295 protein kinase activator activity(GO:0030295)
0.0 0.1 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0 0.7 GO:0030332 cyclin binding(GO:0030332)
0.0 3.4 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.8 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.5 GO:0005112 Notch binding(GO:0005112)
0.0 0.6 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.5 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 1.8 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.2 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.9 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.9 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.4 GO:0031492 nucleosomal DNA binding(GO:0031492)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 4.5 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 1.9 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 1.6 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.7 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 2.0 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.6 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.4 PID REELIN PATHWAY Reelin signaling pathway
0.0 2.2 PID ENDOTHELIN PATHWAY Endothelins
0.0 0.9 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 2.4 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.9 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.5 PID MYC PATHWAY C-MYC pathway
0.0 0.4 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.9 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.2 PID FGF PATHWAY FGF signaling pathway
0.0 0.7 PID CASPASE PATHWAY Caspase cascade in apoptosis

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.7 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 3.7 REACTOME ACYL CHAIN REMODELLING OF PC Genes involved in Acyl chain remodelling of PC
0.1 4.5 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 4.0 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.1 2.7 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 1.3 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 1.4 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.1 0.9 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 1.9 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 0.6 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 2.0 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.8 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.9 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.8 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 1.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.7 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.1 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.3 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 1.7 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 0.3 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.4 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 1.4 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 1.6 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.7 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins