Motif ID: Tfap2c

Z-value: 1.677


Transcription factors associated with Tfap2c:

Gene SymbolEntrez IDGene Name
Tfap2c ENSMUSG00000028640.5 Tfap2c

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tfap2cmm10_v2_chr2_+_172550761_1725507820.582.4e-04Click!


Activity profile for motif Tfap2c.

activity profile for motif Tfap2c


Sorted Z-values histogram for motif Tfap2c

Sorted Z-values for motif Tfap2c



Network of associatons between targets according to the STRING database.



First level regulatory network of Tfap2c

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_+_7268296 15.706 ENSMUST00000066646.4
Rcor2
REST corepressor 2
chr12_+_109459843 15.306 ENSMUST00000173812.1
Dlk1
delta-like 1 homolog (Drosophila)
chr12_-_76709997 12.081 ENSMUST00000166101.1
Sptb
spectrin beta, erythrocytic
chrX_-_142306170 11.230 ENSMUST00000134825.2
Kcne1l
potassium voltage-gated channel, Isk-related family, member 1-like, pseudogene
chr5_+_33658123 11.006 ENSMUST00000074849.6
ENSMUST00000079534.4
Tacc3

transforming, acidic coiled-coil containing protein 3

chr2_-_170427828 9.292 ENSMUST00000013667.2
ENSMUST00000109152.2
ENSMUST00000068137.4
Bcas1


breast carcinoma amplified sequence 1


chr8_+_105518736 9.058 ENSMUST00000034363.5
Hsd11b2
hydroxysteroid 11-beta dehydrogenase 2
chr17_+_48359891 8.931 ENSMUST00000024792.6
Treml1
triggering receptor expressed on myeloid cells-like 1
chr9_+_65101453 8.141 ENSMUST00000077696.6
ENSMUST00000035499.4
ENSMUST00000166273.1
Igdcc4


immunoglobulin superfamily, DCC subclass, member 4


chr8_+_84901928 7.697 ENSMUST00000067060.7
Klf1
Kruppel-like factor 1 (erythroid)
chr17_+_56303321 7.525 ENSMUST00000001258.8
Uhrf1
ubiquitin-like, containing PHD and RING finger domains, 1
chrX_-_7671341 7.142 ENSMUST00000033486.5
Plp2
proteolipid protein 2
chr2_+_29869484 7.020 ENSMUST00000047521.6
ENSMUST00000134152.1
Cercam

cerebral endothelial cell adhesion molecule

chr17_+_56303396 6.960 ENSMUST00000113038.1
Uhrf1
ubiquitin-like, containing PHD and RING finger domains, 1
chr11_+_76998595 6.754 ENSMUST00000108402.2
ENSMUST00000021195.4
Slc6a4

solute carrier family 6 (neurotransmitter transporter, serotonin), member 4

chr11_-_94474088 6.494 ENSMUST00000107786.1
ENSMUST00000107791.1
ENSMUST00000103166.2
ENSMUST00000107792.1
ENSMUST00000100561.3
ENSMUST00000107793.1
ENSMUST00000107788.1
ENSMUST00000107790.1
ENSMUST00000107789.1
ENSMUST00000107785.1
ENSMUST00000021234.8
Cacna1g










calcium channel, voltage-dependent, T type, alpha 1G subunit










chr13_+_73467197 6.242 ENSMUST00000022099.8
Lpcat1
lysophosphatidylcholine acyltransferase 1
chr2_+_103957976 6.241 ENSMUST00000156813.1
ENSMUST00000170926.1
Lmo2

LIM domain only 2

chr11_-_59964936 6.215 ENSMUST00000062405.7
Rasd1
RAS, dexamethasone-induced 1
chr7_-_126414855 6.092 ENSMUST00000032968.5
Cd19
CD19 antigen
chr1_-_193201435 6.077 ENSMUST00000043550.4
Traf3ip3
TRAF3 interacting protein 3
chr2_-_29869785 6.056 ENSMUST00000047607.1
2600006K01Rik
RIKEN cDNA 2600006K01 gene
chr2_-_32083783 6.049 ENSMUST00000056406.6
Fam78a
family with sequence similarity 78, member A
chr7_+_99535652 5.886 ENSMUST00000032995.8
ENSMUST00000162404.1
Arrb1

arrestin, beta 1

chr2_-_152415044 5.759 ENSMUST00000099207.3
Zcchc3
zinc finger, CCHC domain containing 3
chr10_-_45470201 5.564 ENSMUST00000079390.6
Lin28b
lin-28 homolog B (C. elegans)
chr1_+_75479529 5.403 ENSMUST00000113575.2
ENSMUST00000148980.1
ENSMUST00000050899.6
Tmem198


transmembrane protein 198


chr2_-_34913976 5.361 ENSMUST00000028232.3
Phf19
PHD finger protein 19
chr4_-_116464151 5.351 ENSMUST00000106486.1
ENSMUST00000106485.1
Mast2

microtubule associated serine/threonine kinase 2

chr7_-_29518566 5.249 ENSMUST00000181975.1
Sipa1l3
signal-induced proliferation-associated 1 like 3
chr4_+_123282778 4.895 ENSMUST00000106243.1
ENSMUST00000106241.1
ENSMUST00000080178.6
Pabpc4


poly(A) binding protein, cytoplasmic 4


chr2_+_91945703 4.686 ENSMUST00000178895.1
Gm9821
predicted gene 9821
chr7_+_30421724 4.682 ENSMUST00000108176.1
Nfkbid
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, delta
chr4_+_135120640 4.507 ENSMUST00000056977.7
Runx3
runt related transcription factor 3
chr2_-_160912292 4.473 ENSMUST00000109454.1
ENSMUST00000057169.4
Emilin3

elastin microfibril interfacer 3

chr2_-_32353247 4.240 ENSMUST00000078352.5
ENSMUST00000113352.2
ENSMUST00000113365.1
Dnm1


dynamin 1


chr7_+_25627604 4.201 ENSMUST00000076034.6
B3gnt8
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8
chrX_+_71962971 4.177 ENSMUST00000048790.6
Prrg3
proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane)
chrX_-_133688978 4.020 ENSMUST00000149154.1
ENSMUST00000167944.1
Pcdh19

protocadherin 19

chr14_-_65262391 3.945 ENSMUST00000131309.1
Fzd3
frizzled homolog 3 (Drosophila)
chr1_-_75479271 3.913 ENSMUST00000079205.7
ENSMUST00000094818.2
Chpf

chondroitin polymerizing factor

chr6_+_4504814 3.891 ENSMUST00000141483.1
Col1a2
collagen, type I, alpha 2
chr5_+_137758133 3.815 ENSMUST00000141733.1
ENSMUST00000110985.1
Tsc22d4

TSC22 domain family, member 4

chr10_-_127341583 3.797 ENSMUST00000026474.3
Gli1
GLI-Kruppel family member GLI1
chr8_+_70493156 3.749 ENSMUST00000008032.7
Crlf1
cytokine receptor-like factor 1
chr4_+_111414959 3.741 ENSMUST00000030274.6
Bend5
BEN domain containing 5
chr15_-_101712891 3.695 ENSMUST00000023709.5
Krt5
keratin 5
chr6_-_83033422 3.596 ENSMUST00000089651.5
Dok1
docking protein 1
chr13_-_49248146 3.580 ENSMUST00000119721.1
ENSMUST00000058196.6
Susd3

sushi domain containing 3

chr3_-_88503187 3.375 ENSMUST00000120377.1
Lmna
lamin A
chr6_+_88198656 3.366 ENSMUST00000015197.7
Gata2
GATA binding protein 2
chr1_-_172027251 3.254 ENSMUST00000138714.1
Vangl2
vang-like 2 (van gogh, Drosophila)
chr6_-_28831747 3.251 ENSMUST00000062304.5
Lrrc4
leucine rich repeat containing 4
chr7_-_4812351 3.243 ENSMUST00000079496.7
Ube2s
ubiquitin-conjugating enzyme E2S
chr11_+_61684419 3.240 ENSMUST00000093019.5
Fam83g
family with sequence similarity 83, member G
chr17_+_24473884 3.234 ENSMUST00000054946.3
ENSMUST00000164508.1
Bricd5

BRICHOS domain containing 5

chr11_-_120348475 3.232 ENSMUST00000062147.7
ENSMUST00000128055.1
Actg1

actin, gamma, cytoplasmic 1

chr11_-_103356324 3.194 ENSMUST00000136491.2
ENSMUST00000107023.2
Arhgap27

Rho GTPase activating protein 27

chr1_-_44061936 3.165 ENSMUST00000168641.1
Gm8251
predicted gene 8251
chr2_-_153529941 3.156 ENSMUST00000035346.7
8430427H17Rik
RIKEN cDNA 8430427H17 gene
chr1_-_172027269 3.154 ENSMUST00000027837.6
ENSMUST00000111264.1
Vangl2

vang-like 2 (van gogh, Drosophila)

chr9_-_65391652 3.125 ENSMUST00000068307.3
Kbtbd13
kelch repeat and BTB (POZ) domain containing 13
chr1_-_75264195 3.083 ENSMUST00000027404.5
Ptprn
protein tyrosine phosphatase, receptor type, N
chr10_-_88379051 3.060 ENSMUST00000138159.1
Dram1
DNA-damage regulated autophagy modulator 1
chr2_+_167062934 2.958 ENSMUST00000125674.1
1500012F01Rik
RIKEN cDNA 1500012F01 gene
chr1_+_82839449 2.946 ENSMUST00000113444.1
ENSMUST00000063380.4
Agfg1

ArfGAP with FG repeats 1

chr4_+_104367549 2.934 ENSMUST00000106830.2
Dab1
disabled 1
chr12_-_103242143 2.905 ENSMUST00000074416.3
Prima1
proline rich membrane anchor 1
chr13_+_55445301 2.905 ENSMUST00000001115.8
ENSMUST00000099482.3
Grk6

G protein-coupled receptor kinase 6

chr4_+_45203921 2.858 ENSMUST00000107804.1
Frmpd1
FERM and PDZ domain containing 1
chr14_+_79451791 2.855 ENSMUST00000100359.1
Zbtbd6
kelch repeat and BTB (POZ) domain containing 6
chr11_+_3289880 2.824 ENSMUST00000110043.1
ENSMUST00000094471.3
Patz1

POZ (BTB) and AT hook containing zinc finger 1

chr15_+_76457438 2.804 ENSMUST00000043089.7
Scx
scleraxis
chr3_-_88503331 2.795 ENSMUST00000029699.6
Lmna
lamin A
chr2_+_76406529 2.785 ENSMUST00000111929.1
ENSMUST00000077972.4
ENSMUST00000111930.2
Osbpl6


oxysterol binding protein-like 6


chr19_+_7417586 2.770 ENSMUST00000159348.1
2700081O15Rik
RIKEN cDNA 2700081O15 gene
chrX_-_101085352 2.767 ENSMUST00000101362.1
ENSMUST00000073927.4
Slc7a3

solute carrier family 7 (cationic amino acid transporter, y+ system), member 3

chr8_+_122282117 2.760 ENSMUST00000054052.8
Zfpm1
zinc finger protein, multitype 1
chr5_+_147430407 2.587 ENSMUST00000176600.1
Pan3
PAN3 polyA specific ribonuclease subunit homolog (S. cerevisiae)
chr19_+_5068077 2.549 ENSMUST00000070630.6
Cd248
CD248 antigen, endosialin
chr6_+_4505493 2.527 ENSMUST00000031668.8
Col1a2
collagen, type I, alpha 2
chr2_+_130274437 2.500 ENSMUST00000141872.1
Nop56
NOP56 ribonucleoprotein
chrX_+_56447965 2.482 ENSMUST00000079663.6
Gm2174
predicted gene 2174
chr10_+_62252325 2.462 ENSMUST00000020278.5
Tacr2
tachykinin receptor 2
chr2_+_156421083 2.458 ENSMUST00000125153.2
ENSMUST00000103136.1
ENSMUST00000109577.2
Epb4.1l1


erythrocyte protein band 4.1-like 1


chr17_+_35866606 2.430 ENSMUST00000113814.4
Ppp1r18
protein phosphatase 1, regulatory subunit 18
chr6_-_12749193 2.422 ENSMUST00000046121.6
ENSMUST00000172356.1
Thsd7a

thrombospondin, type I, domain containing 7A

chr2_-_152398046 2.420 ENSMUST00000063332.8
ENSMUST00000182625.1
Sox12

SRY-box containing gene 12

chr10_+_11281583 2.419 ENSMUST00000070300.4
Fbxo30
F-box protein 30
chr2_+_156421048 2.386 ENSMUST00000109574.1
Epb4.1l1
erythrocyte protein band 4.1-like 1
chr18_+_86394952 2.385 ENSMUST00000058829.2
Neto1
neuropilin (NRP) and tolloid (TLL)-like 1
chr5_-_149051300 2.383 ENSMUST00000110505.1
Hmgb1
high mobility group box 1
chr19_-_46039621 2.350 ENSMUST00000056931.7
Ldb1
LIM domain binding 1
chr14_-_24245913 2.346 ENSMUST00000073687.6
ENSMUST00000090398.4
Dlg5

discs, large homolog 5 (Drosophila)

chr11_-_78183551 2.338 ENSMUST00000102483.4
Rpl23a
ribosomal protein L23A
chr9_-_105828085 2.306 ENSMUST00000166431.2
ENSMUST00000098441.3
Col6a6

collagen, type VI, alpha 6

chr5_-_35679416 2.304 ENSMUST00000114233.2
Htra3
HtrA serine peptidase 3
chr4_-_136835843 2.293 ENSMUST00000105846.2
ENSMUST00000059287.7
ENSMUST00000105845.2
Ephb2


Eph receptor B2


chr6_+_38663061 2.259 ENSMUST00000114874.3
Clec2l
C-type lectin domain family 2, member L
chr2_+_156420837 2.245 ENSMUST00000103137.3
Epb4.1l1
erythrocyte protein band 4.1-like 1
chr4_+_133480126 2.239 ENSMUST00000051676.6
Fam46b
family with sequence similarity 46, member B
chr19_-_7341433 2.238 ENSMUST00000165965.1
ENSMUST00000051711.9
ENSMUST00000169541.1
ENSMUST00000165989.1
Mark2



MAP/microtubule affinity-regulating kinase 2



chr4_-_154636831 2.200 ENSMUST00000030902.6
ENSMUST00000105637.1
ENSMUST00000070313.7
ENSMUST00000105636.1
ENSMUST00000105638.2
ENSMUST00000097759.2
ENSMUST00000124771.1
Prdm16






PR domain containing 16






chr7_+_127777095 2.123 ENSMUST00000144406.1
Setd1a
SET domain containing 1A
chr7_+_25221417 2.095 ENSMUST00000055604.4
Zfp526
zinc finger protein 526
chr10_+_11281304 2.069 ENSMUST00000129456.1
Fbxo30
F-box protein 30
chr17_+_29660710 2.068 ENSMUST00000130423.1
Cmtr1
cap methyltransferase 1
chr19_-_3929723 2.067 ENSMUST00000051803.6
Aldh3b1
aldehyde dehydrogenase 3 family, member B1
chr4_-_136602641 2.058 ENSMUST00000105847.1
ENSMUST00000116273.2
Kdm1a

lysine (K)-specific demethylase 1A

chr2_+_130274424 2.012 ENSMUST00000103198.4
Nop56
NOP56 ribonucleoprotein
chr13_-_23622502 2.006 ENSMUST00000062045.2
Hist1h1e
histone cluster 1, H1e
chr8_-_85067982 1.999 ENSMUST00000177563.1
Gm5741
predicted gene 5741
chr5_-_122989086 1.954 ENSMUST00000046073.9
Kdm2b
lysine (K)-specific demethylase 2B
chr8_-_102785093 1.952 ENSMUST00000075190.3
Cdh11
cadherin 11
chr15_+_98634743 1.930 ENSMUST00000003442.7
Cacnb3
calcium channel, voltage-dependent, beta 3 subunit
chr3_+_59006978 1.915 ENSMUST00000040325.7
ENSMUST00000164225.1
ENSMUST00000040846.8
ENSMUST00000029393.8
Med12l



mediator of RNA polymerase II transcription, subunit 12 homolog (yeast)-like



chr13_+_54371340 1.912 ENSMUST00000026985.8
Cplx2
complexin 2
chr11_+_3289168 1.900 ENSMUST00000134089.1
Patz1
POZ (BTB) and AT hook containing zinc finger 1
chr4_+_40473130 1.887 ENSMUST00000179526.1
Tmem215
transmembrane protein 215
chr7_-_104390586 1.874 ENSMUST00000106828.1
Trim30c
tripartite motif-containing 30C
chr7_+_90130227 1.827 ENSMUST00000049537.7
Picalm
phosphatidylinositol binding clathrin assembly protein
chr18_-_60848911 1.811 ENSMUST00000177172.1
ENSMUST00000175934.1
ENSMUST00000176630.1
Tcof1


Treacher Collins Franceschetti syndrome 1, homolog


chr5_-_122989260 1.809 ENSMUST00000118027.1
Kdm2b
lysine (K)-specific demethylase 2B
chr7_-_19604444 1.797 ENSMUST00000086041.5
Clasrp
CLK4-associating serine/arginine rich protein
chr9_-_76567092 1.788 ENSMUST00000183437.1
Fam83b
family with sequence similarity 83, member B
chr4_+_131873608 1.774 ENSMUST00000053819.3
Srsf4
serine/arginine-rich splicing factor 4
chr11_-_69413675 1.742 ENSMUST00000094077.4
Kdm6b
KDM1 lysine (K)-specific demethylase 6B
chr18_-_61036189 1.724 ENSMUST00000025521.8
Cdx1
caudal type homeobox 1
chr5_-_122900267 1.697 ENSMUST00000031435.7
Kdm2b
lysine (K)-specific demethylase 2B
chrX_-_73824938 1.686 ENSMUST00000114438.2
ENSMUST00000002080.5
Pdzd4

PDZ domain containing 4

chr8_-_87959560 1.662 ENSMUST00000109655.2
Zfp423
zinc finger protein 423
chr14_+_31251454 1.642 ENSMUST00000022458.4
Bap1
Brca1 associated protein 1
chr5_+_139352607 1.574 ENSMUST00000031521.8
Cyp2w1
cytochrome P450, family 2, subfamily w, polypeptide 1
chr3_-_9610074 1.558 ENSMUST00000041124.7
Zfp704
zinc finger protein 704
chr2_+_119897212 1.538 ENSMUST00000046717.6
ENSMUST00000110774.1
ENSMUST00000110773.2
ENSMUST00000079934.5
ENSMUST00000156510.1
Mga




MAX gene associated




chr10_+_24223517 1.522 ENSMUST00000095784.2
Moxd1
monooxygenase, DBH-like 1
chr11_-_120990871 1.511 ENSMUST00000154483.1
Csnk1d
casein kinase 1, delta
chr3_-_27710413 1.510 ENSMUST00000046157.4
Fndc3b
fibronectin type III domain containing 3B
chr9_+_108002501 1.508 ENSMUST00000035214.4
ENSMUST00000175874.1
Ip6k1

inositol hexaphosphate kinase 1

chr7_-_25788635 1.495 ENSMUST00000002677.4
ENSMUST00000085948.4
Axl

AXL receptor tyrosine kinase

chr5_+_144545883 1.481 ENSMUST00000071782.6
Nptx2
neuronal pentraxin 2
chr8_-_116732991 1.479 ENSMUST00000109102.2
Cdyl2
chromodomain protein, Y chromosome-like 2
chr2_+_74704861 1.468 ENSMUST00000019749.3
Hoxd8
homeobox D8
chr6_+_118066356 1.465 ENSMUST00000164960.1
Rasgef1a
RasGEF domain family, member 1A
chr6_-_42693087 1.453 ENSMUST00000121083.1
Fam115a
family with sequence similarity 115, member A
chr4_-_44711446 1.442 ENSMUST00000014174.7
Pax5
paired box gene 5
chr2_+_74705145 1.424 ENSMUST00000074721.5
Hoxd8
homeobox D8
chr5_-_147307264 1.414 ENSMUST00000031650.3
Cdx2
caudal type homeobox 2
chr3_-_61365951 1.412 ENSMUST00000066298.2
B430305J03Rik
RIKEN cDNA B430305J03 gene
chr8_-_84687839 1.404 ENSMUST00000001975.4
Nacc1
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
chr4_-_120287349 1.399 ENSMUST00000102656.3
Foxo6
forkhead box O6
chr7_+_25282784 1.391 ENSMUST00000165239.1
Cic
capicua homolog (Drosophila)
chr15_+_76351288 1.371 ENSMUST00000161527.1
ENSMUST00000160853.1
Maf1

MAF1 homolog (S. cerevisiae)

chr5_-_149051604 1.363 ENSMUST00000093196.4
Hmgb1
high mobility group box 1
chr1_-_167466780 1.363 ENSMUST00000036643.4
Lrrc52
leucine rich repeat containing 52
chr17_+_29660595 1.339 ENSMUST00000024816.6
Cmtr1
cap methyltransferase 1
chrX_-_48034842 1.328 ENSMUST00000039026.7
Apln
apelin
chr18_-_6490808 1.308 ENSMUST00000028100.6
ENSMUST00000050542.5
Epc1

enhancer of polycomb homolog 1 (Drosophila)

chr2_+_152736244 1.283 ENSMUST00000038368.8
ENSMUST00000109824.1
Id1

inhibitor of DNA binding 1

chr16_+_35154870 1.273 ENSMUST00000114913.1
Adcy5
adenylate cyclase 5
chr3_-_154597045 1.257 ENSMUST00000052774.1
ENSMUST00000170461.1
ENSMUST00000122976.1
Tyw3


tRNA-yW synthesizing protein 3 homolog (S. cerevisiae)


chr1_-_161788489 1.241 ENSMUST00000000834.2
Fasl
Fas ligand (TNF superfamily, member 6)
chr18_+_74216118 1.223 ENSMUST00000025444.6
Cxxc1
CXXC finger 1 (PHD domain)
chr11_-_69398226 1.197 ENSMUST00000050140.5
Tmem88
transmembrane protein 88
chr3_-_108086590 1.182 ENSMUST00000102638.1
ENSMUST00000102637.1
Ampd2

adenosine monophosphate deaminase 2

chr7_+_127777376 1.180 ENSMUST00000126761.1
ENSMUST00000047157.6
Setd1a

SET domain containing 1A

chr6_-_42693030 1.173 ENSMUST00000045140.4
Fam115a
family with sequence similarity 115, member A
chr11_-_65162904 1.162 ENSMUST00000093002.5
ENSMUST00000047463.8
Arhgap44

Rho GTPase activating protein 44

chrX_+_71556874 1.143 ENSMUST00000123100.1
Hmgb3
high mobility group box 3
chr2_-_157204483 1.143 ENSMUST00000029170.7
Rbl1
retinoblastoma-like 1 (p107)
chr2_+_3118335 1.143 ENSMUST00000115099.2
Fam171a1
family with sequence similarity 171, member A1
chr15_-_36608959 1.089 ENSMUST00000001809.8
Pabpc1
poly(A) binding protein, cytoplasmic 1
chr15_+_100761741 1.030 ENSMUST00000023776.6
Slc4a8
solute carrier family 4 (anion exchanger), member 8
chr9_+_89909775 1.024 ENSMUST00000034912.4
ENSMUST00000034909.4
Rasgrf1

RAS protein-specific guanine nucleotide-releasing factor 1

chr17_+_35866056 1.015 ENSMUST00000122899.1
Ppp1r18
protein phosphatase 1, regulatory subunit 18
chr4_+_152338619 0.974 ENSMUST00000030775.5
ENSMUST00000164662.1
Chd5

chromodomain helicase DNA binding protein 5

chr4_+_63215402 0.950 ENSMUST00000036300.6
Col27a1
collagen, type XXVII, alpha 1
chr5_-_124354671 0.934 ENSMUST00000031341.4
Cdk2ap1
CDK2 (cyclin-dependent kinase 2)-associated protein 1
chr19_-_28680077 0.907 ENSMUST00000162022.1
ENSMUST00000112612.2
Glis3

GLIS family zinc finger 3

chr4_-_142084221 0.905 ENSMUST00000036572.3
Tmem51
transmembrane protein 51
chr14_+_119138415 0.904 ENSMUST00000065904.3
Hs6st3
heparan sulfate 6-O-sulfotransferase 3
chr5_-_131307848 0.894 ENSMUST00000086023.5
Wbscr17
Williams-Beuren syndrome chromosome region 17 homolog (human)
chr13_-_112652295 0.893 ENSMUST00000099166.2
ENSMUST00000075748.5
Ddx4

DEAD (Asp-Glu-Ala-Asp) box polypeptide 4

chr19_-_45998479 0.886 ENSMUST00000045396.7
9130011E15Rik
RIKEN cDNA 9130011E15 gene
chr8_-_104631312 0.886 ENSMUST00000034351.6
Rrad
Ras-related associated with diabetes
chr11_-_116110211 0.865 ENSMUST00000106441.1
ENSMUST00000021120.5
Trim47

tripartite motif-containing 47

chr7_+_3290553 0.852 ENSMUST00000096744.5
Myadm
myeloid-associated differentiation marker
chr11_-_120991039 0.849 ENSMUST00000070575.7
Csnk1d
casein kinase 1, delta
chr16_+_17070220 0.823 ENSMUST00000141959.1
Ypel1
yippee-like 1 (Drosophila)
chr5_+_150952607 0.819 ENSMUST00000078856.6
Kl
klotho
chr19_+_5568002 0.806 ENSMUST00000096318.3
Ap5b1
adaptor-related protein complex 5, beta 1 subunit
chr19_+_10041548 0.795 ENSMUST00000115995.2
Fads3
fatty acid desaturase 3
chrX_+_163909132 0.781 ENSMUST00000033734.7
ENSMUST00000112294.2
Ap1s2

adaptor-related protein complex 1, sigma 2 subunit

chr3_+_103914560 0.779 ENSMUST00000106806.1
Rsbn1
rosbin, round spermatid basic protein 1
chr1_-_63114516 0.776 ENSMUST00000097718.2
Ino80d
INO80 complex subunit D
chr7_+_105736702 0.772 ENSMUST00000163389.1
ENSMUST00000136687.1
Ilk

integrin linked kinase

chr2_+_165503787 0.766 ENSMUST00000029196.4
Slc2a10
solute carrier family 2 (facilitated glucose transporter), member 10
chr12_-_81333129 0.764 ENSMUST00000085238.6
ENSMUST00000182208.1
Slc8a3

solute carrier family 8 (sodium/calcium exchanger), member 3

chr11_+_102189620 0.741 ENSMUST00000070334.3
ENSMUST00000078975.7
G6pc3

glucose 6 phosphatase, catalytic, 3

chr8_+_105605220 0.728 ENSMUST00000043531.8
Fam65a
family with sequence similarity 65, member A

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 9.1 GO:0002017 regulation of blood volume by renal aldosterone(GO:0002017)
1.7 10.4 GO:0036515 serotonergic neuron axon guidance(GO:0036515)
1.7 6.8 GO:0021941 negative regulation of cerebellar granule cell precursor proliferation(GO:0021941)
1.6 6.3 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
1.6 6.2 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
1.4 2.8 GO:0090202 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
1.2 3.7 GO:0002270 plasmacytoid dendritic cell activation(GO:0002270)
1.2 6.2 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
1.1 8.0 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
1.1 3.4 GO:0097309 cap1 mRNA methylation(GO:0097309)
1.1 5.5 GO:0021993 initiation of neural tube closure(GO:0021993)
1.1 5.4 GO:0010725 regulation of primitive erythrocyte differentiation(GO:0010725)
1.1 4.2 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
1.0 3.1 GO:0061792 secretory granule maturation(GO:0061792)
1.0 5.9 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
1.0 14.5 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.9 3.8 GO:0060032 notochord regression(GO:0060032)
0.9 2.8 GO:0015819 lysine transport(GO:0015819)
0.8 3.2 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.8 2.4 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.7 2.9 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812) lateral motor column neuron migration(GO:0097477)
0.7 2.9 GO:0010360 negative regulation of anion channel activity(GO:0010360)
0.7 1.3 GO:0051466 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) positive regulation of corticotropin-releasing hormone secretion(GO:0051466)
0.6 5.6 GO:0010587 miRNA catabolic process(GO:0010587)
0.6 4.2 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.6 2.3 GO:0043973 histone H3-K4 acetylation(GO:0043973)
0.6 4.7 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
0.6 9.9 GO:0030953 astral microtubule organization(GO:0030953)
0.6 2.8 GO:0035990 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.5 3.7 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.5 15.3 GO:0045780 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.5 6.2 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.5 3.6 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.5 7.7 GO:0043249 erythrocyte maturation(GO:0043249)
0.5 1.5 GO:0006589 octopamine biosynthetic process(GO:0006589) octopamine metabolic process(GO:0046333)
0.5 2.5 GO:0070459 acetylcholine secretion, neurotransmission(GO:0014055) regulation of acetylcholine secretion, neurotransmission(GO:0014056) operant conditioning(GO:0035106) prolactin secretion(GO:0070459)
0.4 2.2 GO:1905424 regulation of Wnt-mediated midbrain dopaminergic neuron differentiation(GO:1905424) positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation(GO:1905426)
0.4 6.5 GO:0043589 skin morphogenesis(GO:0043589)
0.4 1.6 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.4 6.1 GO:0006968 cellular defense response(GO:0006968)
0.4 1.6 GO:0043385 mycotoxin metabolic process(GO:0043385) aflatoxin metabolic process(GO:0046222) organic heteropentacyclic compound metabolic process(GO:1901376)
0.4 3.9 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.4 5.4 GO:0045075 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.4 3.8 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.4 1.5 GO:0097350 neutrophil clearance(GO:0097350)
0.4 1.8 GO:1905247 positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) negative regulation of metalloendopeptidase activity(GO:1904684) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.3 2.3 GO:0035331 negative regulation of hippo signaling(GO:0035331) protein localization to adherens junction(GO:0071896)
0.3 3.3 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.3 1.2 GO:0098887 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887)
0.3 2.6 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.3 2.0 GO:0016584 nucleosome positioning(GO:0016584)
0.3 12.1 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.3 4.2 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.3 1.3 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.2 1.2 GO:0035617 stress granule disassembly(GO:0035617)
0.2 1.2 GO:0097527 necroptotic signaling pathway(GO:0097527)
0.2 3.1 GO:0014807 regulation of somitogenesis(GO:0014807)
0.2 6.2 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.2 3.3 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.2 0.7 GO:0002309 T cell proliferation involved in immune response(GO:0002309)
0.2 1.1 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.2 0.9 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.2 1.1 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.2 1.7 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.2 2.5 GO:0060033 anatomical structure regression(GO:0060033)
0.2 1.4 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.2 0.6 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.2 0.9 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.2 1.8 GO:0014029 neural crest formation(GO:0014029)
0.2 1.9 GO:0098903 regulation of membrane repolarization during action potential(GO:0098903)
0.2 1.3 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.2 0.5 GO:1903406 regulation of sodium:potassium-exchanging ATPase activity(GO:1903406)
0.2 1.0 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.2 1.5 GO:0006020 inositol metabolic process(GO:0006020)
0.2 0.9 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 2.9 GO:0001675 acrosome assembly(GO:0001675)
0.1 0.6 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.1 2.2 GO:0030853 negative regulation of granulocyte differentiation(GO:0030853)
0.1 1.2 GO:0032264 IMP salvage(GO:0032264)
0.1 4.5 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.1 0.5 GO:0051344 negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.1 0.4 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.1 0.7 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 4.5 GO:0000154 rRNA modification(GO:0000154)
0.1 0.6 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1 0.8 GO:0042421 norepinephrine biosynthetic process(GO:0042421)
0.1 0.4 GO:1904742 protein poly-ADP-ribosylation(GO:0070212) protein auto-ADP-ribosylation(GO:0070213) regulation of telomeric DNA binding(GO:1904742)
0.1 4.7 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 0.4 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.1 0.5 GO:1902167 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902167)
0.1 1.5 GO:0060510 Type II pneumocyte differentiation(GO:0060510)
0.1 2.1 GO:0046185 aldehyde catabolic process(GO:0046185)
0.1 1.4 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.1 11.2 GO:0030168 platelet activation(GO:0030168)
0.1 4.9 GO:0061515 myeloid cell development(GO:0061515)
0.1 0.4 GO:1905664 negative regulation of dendritic spine maintenance(GO:1902951) regulation of calcium ion import across plasma membrane(GO:1905664)
0.1 0.6 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 1.0 GO:2000310 regulation of NMDA receptor activity(GO:2000310)
0.1 1.4 GO:0021670 lateral ventricle development(GO:0021670)
0.1 0.2 GO:1905832 minus-end-directed vesicle transport along microtubule(GO:0072382) positive regulation of spindle assembly(GO:1905832)
0.1 0.3 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.1 1.3 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 0.5 GO:0007000 nucleolus organization(GO:0007000)
0.1 0.2 GO:0008358 oocyte construction(GO:0007308) oocyte axis specification(GO:0007309) oocyte anterior/posterior axis specification(GO:0007314) pole plasm assembly(GO:0007315) maternal determination of anterior/posterior axis, embryo(GO:0008358) P granule organization(GO:0030719)
0.1 0.8 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cytosol(GO:1902656)
0.1 5.0 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.1 2.2 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.1 2.2 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 1.8 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.6 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.5 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.0 1.7 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.9 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.3 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.3 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.4 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 2.3 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 4.7 GO:0008584 male gonad development(GO:0008584) development of primary male sexual characteristics(GO:0046546)
0.0 0.2 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.9 GO:0060325 face morphogenesis(GO:0060325)
0.0 2.0 GO:0048286 lung alveolus development(GO:0048286)
0.0 0.2 GO:0046015 regulation of transcription by glucose(GO:0046015)
0.0 0.8 GO:1904659 glucose transmembrane transport(GO:1904659)
0.0 1.1 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 1.0 GO:0015701 bicarbonate transport(GO:0015701)
0.0 2.3 GO:0008306 associative learning(GO:0008306)
0.0 1.7 GO:0030509 BMP signaling pathway(GO:0030509)
0.0 0.3 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.4 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 1.8 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.0 0.9 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.6 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.3 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.2 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.1 GO:0031053 primary miRNA processing(GO:0031053)
0.0 0.1 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 6.4 GO:0005584 collagen type I trimer(GO:0005584)
1.7 12.1 GO:0008091 spectrin(GO:0008091)
1.6 6.4 GO:0060187 cell pole(GO:0060187)
0.9 3.7 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.9 6.2 GO:0005638 lamin filament(GO:0005638)
0.9 2.6 GO:0031251 PAN complex(GO:0031251)
0.7 5.2 GO:0061689 tricellular tight junction(GO:0061689)
0.6 4.5 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.6 1.8 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.5 1.8 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.4 8.9 GO:0031091 platelet alpha granule(GO:0031091)
0.3 5.9 GO:0031143 pseudopodium(GO:0031143)
0.3 17.8 GO:0000791 euchromatin(GO:0000791)
0.3 3.8 GO:0097542 ciliary tip(GO:0097542)
0.3 1.3 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.2 2.2 GO:0097427 microtubule bundle(GO:0097427)
0.2 3.9 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.2 1.9 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.2 3.9 GO:0032433 filopodium tip(GO:0032433)
0.2 4.2 GO:0043196 varicosity(GO:0043196)
0.2 22.5 GO:0017053 transcriptional repressor complex(GO:0017053)
0.2 3.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.2 6.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 0.9 GO:0071547 piP-body(GO:0071547)
0.1 2.3 GO:0031932 TORC2 complex(GO:0031932)
0.1 3.2 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 5.7 GO:0031519 PcG protein complex(GO:0031519)
0.1 0.6 GO:0044194 cytolytic granule(GO:0044194) tertiary granule(GO:0070820)
0.1 2.8 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 1.0 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 1.2 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 6.0 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 2.4 GO:0098839 postsynaptic density membrane(GO:0098839)
0.1 4.0 GO:0043034 costamere(GO:0043034)
0.1 6.2 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.1 0.3 GO:1990032 parallel fiber(GO:1990032)
0.1 7.8 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 1.5 GO:0033643 host cell part(GO:0033643)
0.1 1.2 GO:0035253 ciliary rootlet(GO:0035253)
0.1 1.5 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1 2.0 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 1.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 1.9 GO:0016592 mediator complex(GO:0016592) core mediator complex(GO:0070847)
0.0 1.0 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 14.3 GO:0014069 postsynaptic density(GO:0014069) asymmetric synapse(GO:0032279)
0.0 2.1 GO:0005876 spindle microtubule(GO:0005876)
0.0 2.1 GO:1990391 DNA repair complex(GO:1990391)
0.0 15.1 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.5 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.4 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 2.6 GO:0005811 lipid droplet(GO:0005811)
0.0 0.2 GO:0002177 manchette(GO:0002177)
0.0 0.5 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.4 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 2.1 GO:0043197 dendritic spine(GO:0043197)
0.0 2.4 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.6 GO:0045095 keratin filament(GO:0045095)
0.0 9.4 GO:0005813 centrosome(GO:0005813)
0.0 0.5 GO:0005771 multivesicular body(GO:0005771)
0.0 0.8 GO:0016235 aggresome(GO:0016235)
0.0 0.4 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.8 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 1.9 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 6.6 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.8 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.7 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 1.1 GO:0005694 chromosome(GO:0005694)
0.0 10.5 GO:0005730 nucleolus(GO:0005730)
0.0 0.9 GO:0030864 cortical actin cytoskeleton(GO:0030864)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 9.1 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
2.4 14.5 GO:0031493 nucleosomal histone binding(GO:0031493)
2.3 6.8 GO:0005330 dopamine:sodium symporter activity(GO:0005330)
2.1 6.2 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
2.0 5.9 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
1.4 4.2 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
1.3 3.9 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
1.3 6.5 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
1.2 3.7 GO:0000402 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
0.9 1.7 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.9 3.4 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.8 2.5 GO:0004995 tachykinin receptor activity(GO:0004995)
0.7 2.9 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.6 1.8 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.6 8.0 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.6 2.8 GO:0015189 L-ornithine transmembrane transporter activity(GO:0000064) L-lysine transmembrane transporter activity(GO:0015189)
0.5 1.5 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.5 3.3 GO:1990188 euchromatin binding(GO:1990188)
0.5 3.7 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.4 4.7 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.4 6.4 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.4 2.1 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.3 4.5 GO:1990226 histone methyltransferase binding(GO:1990226)
0.3 1.8 GO:1902944 aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902944)
0.3 1.5 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.3 2.1 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.3 2.3 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.3 5.5 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.3 2.0 GO:0032564 dATP binding(GO:0032564)
0.3 1.4 GO:0001032 RNA polymerase III type 3 promoter DNA binding(GO:0001032)
0.3 1.6 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.2 0.7 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.2 1.2 GO:0045322 unmethylated CpG binding(GO:0045322)
0.2 6.0 GO:0008266 poly(U) RNA binding(GO:0008266)
0.2 0.9 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.2 1.3 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.2 0.8 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.2 7.1 GO:0019956 chemokine binding(GO:0019956)
0.2 0.6 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.2 2.3 GO:0030274 LIM domain binding(GO:0030274)
0.2 0.6 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.2 0.6 GO:0061547 glycogen synthase activity, transferring glucose-1-phosphate(GO:0061547)
0.2 6.2 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.2 3.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.2 2.9 GO:0043495 protein membrane anchor(GO:0043495)
0.2 9.0 GO:0070888 E-box binding(GO:0070888)
0.2 6.2 GO:0030506 ankyrin binding(GO:0030506)
0.2 0.6 GO:0030348 syntaxin-3 binding(GO:0030348)
0.2 4.4 GO:0050321 tau-protein kinase activity(GO:0050321)
0.2 3.4 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.1 0.4 GO:0034437 glycoprotein transporter activity(GO:0034437)
0.1 2.6 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 1.2 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.4 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.1 2.1 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 4.7 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 4.9 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.1 5.3 GO:0140034 methylated histone binding(GO:0035064) methylation-dependent protein binding(GO:0140034)
0.1 2.3 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 0.6 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 2.8 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 1.8 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 3.5 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 1.3 GO:0070628 proteasome binding(GO:0070628)
0.1 3.6 GO:0005158 insulin receptor binding(GO:0005158)
0.1 0.2 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.1 0.5 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 1.2 GO:0005123 death receptor binding(GO:0005123)
0.1 0.5 GO:0000293 ferric-chelate reductase activity(GO:0000293) cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 0.6 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 0.8 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 1.0 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 6.2 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.4 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 12.1 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.5 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 4.8 GO:0046332 SMAD binding(GO:0046332)
0.0 4.3 GO:0008013 beta-catenin binding(GO:0008013)
0.0 1.6 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.9 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.4 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.1 GO:0070878 primary miRNA binding(GO:0070878)
0.0 1.8 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 2.2 GO:0030507 spectrin binding(GO:0030507)
0.0 1.1 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 3.2 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.5 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.8 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.0 0.3 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 1.0 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 8.2 GO:0005096 GTPase activator activity(GO:0005096)
0.0 1.0 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.3 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.1 GO:0099103 channel activator activity(GO:0099103) potassium channel activator activity(GO:0099104)
0.0 1.9 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 9.8 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.6 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.3 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.4 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 1.7 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.9 GO:0097110 scaffold protein binding(GO:0097110)
0.0 3.6 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.9 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 11.0 PID_AURORA_A_PATHWAY Aurora A signaling
0.2 15.3 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.2 8.2 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.2 8.4 ST_B_CELL_ANTIGEN_RECEPTOR B Cell Antigen Receptor
0.2 6.4 PID_LYMPH_ANGIOGENESIS_PATHWAY VEGFR3 signaling in lymphatic endothelium
0.1 0.6 ST_PAC1_RECEPTOR_PATHWAY PAC1 Receptor Pathway
0.1 6.1 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 2.9 ST_TUMOR_NECROSIS_FACTOR_PATHWAY Tumor Necrosis Factor Pathway.
0.1 4.2 PID_AMB2_NEUTROPHILS_PATHWAY amb2 Integrin signaling
0.1 3.2 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 5.7 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 0.6 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.1 4.2 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 3.4 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.1 8.2 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 3.6 PID_PTP1B_PATHWAY Signaling events mediated by PTP1B
0.1 1.3 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.1 2.0 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.1 6.8 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.1 3.5 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.1 1.3 PID_IL3_PATHWAY IL3-mediated signaling events
0.1 2.3 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 3.0 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.0 3.4 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.2 PID_THROMBIN_PAR1_PATHWAY PAR1-mediated thrombin signaling events
0.0 0.7 PID_IL2_PI3K_PATHWAY IL2 signaling events mediated by PI3K
0.0 1.8 NABA_COLLAGENS Genes encoding collagen proteins
0.0 0.5 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 1.1 PID_TELOMERASE_PATHWAY Regulation of Telomerase
0.0 0.8 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.0 0.9 ST_FAS_SIGNALING_PATHWAY Fas Signaling Pathway
0.0 0.9 PID_LKB1_PATHWAY LKB1 signaling events
0.0 1.0 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.0 0.3 PID_RAS_PATHWAY Regulation of Ras family activation

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 21.2 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.5 6.8 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.3 6.2 REACTOME_ACYL_CHAIN_REMODELLING_OF_PG Genes involved in Acyl chain remodelling of PG
0.3 4.7 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.3 11.5 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 4.7 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.2 3.9 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.2 3.6 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.2 6.1 REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.2 8.2 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.1 4.5 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 1.3 REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 5.1 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.1 6.2 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.1 1.2 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.1 2.8 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 0.8 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 1.4 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1 2.0 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.1 0.8 REACTOME_PLATELET_CALCIUM_HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 0.6 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 0.8 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 1.1 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
0.0 6.9 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 1.8 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 1.8 REACTOME_MRNA_3_END_PROCESSING Genes involved in mRNA 3'-end processing
0.0 2.4 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.5 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.8 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.4 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 3.0 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.0 0.5 REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.6 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 0.9 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.4 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.5 REACTOME_RNA_POL_I_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.2 REACTOME_DESTABILIZATION_OF_MRNA_BY_AUF1_HNRNP_D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.5 REACTOME_TRANSFERRIN_ENDOCYTOSIS_AND_RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 1.0 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 2.8 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation