Motif ID: Tfcp2

Z-value: 1.736


Transcription factors associated with Tfcp2:

Gene SymbolEntrez IDGene Name
Tfcp2 ENSMUSG00000009733.8 Tfcp2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tfcp2mm10_v2_chr15_-_100551959_1005520100.325.5e-02Click!


Activity profile for motif Tfcp2.

activity profile for motif Tfcp2


Sorted Z-values histogram for motif Tfcp2

Sorted Z-values for motif Tfcp2



Network of associatons between targets according to the STRING database.



First level regulatory network of Tfcp2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_+_75571522 16.596 ENSMUST00000143226.1
ENSMUST00000124259.1
Ggt1

gamma-glutamyltransferase 1

chr8_+_57511833 16.027 ENSMUST00000067925.6
Hmgb2
high mobility group box 2
chr19_-_34166037 13.742 ENSMUST00000025686.7
Ankrd22
ankyrin repeat domain 22
chr8_+_94172618 13.020 ENSMUST00000034214.6
Mt2
metallothionein 2
chr10_+_43579161 12.610 ENSMUST00000058714.8
Cd24a
CD24a antigen
chr17_-_48451510 12.514 ENSMUST00000024794.5
Tspo2
translocator protein 2
chr7_+_96211656 12.313 ENSMUST00000107165.1
Tenm4
teneurin transmembrane protein 4
chr11_+_116532441 11.335 ENSMUST00000106386.1
ENSMUST00000145737.1
ENSMUST00000155102.1
ENSMUST00000063446.6
Sphk1



sphingosine kinase 1



chr5_+_106964319 10.852 ENSMUST00000031221.5
ENSMUST00000117196.2
ENSMUST00000076467.6
Cdc7


cell division cycle 7 (S. cerevisiae)


chr11_-_99438143 10.642 ENSMUST00000017743.2
Krt20
keratin 20
chr3_-_90695706 10.361 ENSMUST00000069960.5
ENSMUST00000117167.1
S100a9

S100 calcium binding protein A9 (calgranulin B)

chr11_+_69045640 9.801 ENSMUST00000108666.1
ENSMUST00000021277.5
Aurkb

aurora kinase B

chr15_+_89322969 9.457 ENSMUST00000066991.5
Adm2
adrenomedullin 2
chrX_+_73639414 9.264 ENSMUST00000019701.8
Dusp9
dual specificity phosphatase 9
chr17_+_28207778 9.148 ENSMUST00000002327.5
Def6
differentially expressed in FDCP 6
chr11_+_11487671 8.520 ENSMUST00000020410.4
4930415F15Rik
RIKEN cDNA 4930415F15 gene
chrX_-_102250940 8.398 ENSMUST00000134887.1
Cited1
Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1
chr8_+_3665747 8.392 ENSMUST00000014118.2
1810033B17Rik
RIKEN cDNA 1810033B17 gene
chr15_-_103537928 8.120 ENSMUST00000023133.6
Ppp1r1a
protein phosphatase 1, regulatory (inhibitor) subunit 1A
chr6_+_134929089 7.777 ENSMUST00000183867.1
ENSMUST00000184991.1
ENSMUST00000183905.1
RP23-45G16.5


RP23-45G16.5


chr9_-_67832325 7.656 ENSMUST00000054500.5
C2cd4a
C2 calcium-dependent domain containing 4A
chr6_+_134929118 7.644 ENSMUST00000185152.1
ENSMUST00000184504.1
RP23-45G16.5

RP23-45G16.5

chr6_+_5390387 7.291 ENSMUST00000183358.1
Asb4
ankyrin repeat and SOCS box-containing 4
chr13_-_100786402 6.797 ENSMUST00000174038.1
ENSMUST00000091295.7
ENSMUST00000072119.8
Ccnb1


cyclin B1


chr4_-_154025657 6.504 ENSMUST00000146426.1
Smim1
small integral membrane protein 1
chr1_+_107511489 6.337 ENSMUST00000064916.2
Serpinb2
serine (or cysteine) peptidase inhibitor, clade B, member 2
chr5_+_33658550 6.333 ENSMUST00000152847.1
Tacc3
transforming, acidic coiled-coil containing protein 3
chr4_-_154025867 6.244 ENSMUST00000130175.1
ENSMUST00000182151.1
Smim1

small integral membrane protein 1

chr1_+_107511416 6.214 ENSMUST00000009356.4
Serpinb2
serine (or cysteine) peptidase inhibitor, clade B, member 2
chr12_+_24708984 6.044 ENSMUST00000154588.1
Rrm2
ribonucleotide reductase M2
chr6_+_127887582 5.907 ENSMUST00000032501.4
Tspan11
tetraspanin 11
chr4_-_154025926 5.816 ENSMUST00000132541.1
ENSMUST00000143047.1
Smim1

small integral membrane protein 1

chr11_-_95914884 5.737 ENSMUST00000038343.6
B4galnt2
beta-1,4-N-acetyl-galactosaminyl transferase 2
chr14_-_37110087 5.629 ENSMUST00000179488.1
2610528A11Rik
RIKEN cDNA 2610528A11 gene
chrX_-_102250775 5.552 ENSMUST00000130589.1
Cited1
Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1
chr4_-_49593875 5.547 ENSMUST00000151542.1
Tmem246
transmembrane protein 246
chr5_+_33658567 5.270 ENSMUST00000114426.3
Tacc3
transforming, acidic coiled-coil containing protein 3
chr11_+_96929260 5.266 ENSMUST00000054311.5
ENSMUST00000107636.3
Prr15l

proline rich 15-like

chr17_-_25727364 5.056 ENSMUST00000170070.1
ENSMUST00000048054.7
Chtf18

CTF18, chromosome transmission fidelity factor 18

chr11_+_23256001 4.857 ENSMUST00000020538.6
ENSMUST00000109551.1
ENSMUST00000102870.1
ENSMUST00000102869.1
Xpo1



exportin 1, CRM1 homolog (yeast)



chr13_+_91461050 4.825 ENSMUST00000004094.8
ENSMUST00000042122.8
Ssbp2

single-stranded DNA binding protein 2

chr2_+_85136355 4.819 ENSMUST00000057019.7
Aplnr
apelin receptor
chr1_+_130731963 4.786 ENSMUST00000039323.6
AA986860
expressed sequence AA986860
chr19_-_40588374 4.775 ENSMUST00000175932.1
ENSMUST00000176955.1
ENSMUST00000149476.2
Aldh18a1


aldehyde dehydrogenase 18 family, member A1


chr4_-_154025616 4.774 ENSMUST00000182191.1
ENSMUST00000146543.2
Smim1

small integral membrane protein 1

chr7_-_4546567 4.693 ENSMUST00000065957.5
Syt5
synaptotagmin V
chr19_-_40588453 4.662 ENSMUST00000025979.6
Aldh18a1
aldehyde dehydrogenase 18 family, member A1
chr15_-_74734313 4.598 ENSMUST00000023260.3
Lypd2
Ly6/Plaur domain containing 2
chrX_-_164076100 4.564 ENSMUST00000037928.2
ENSMUST00000071667.2
Siah1b

seven in absentia 1B

chr19_-_40588338 4.405 ENSMUST00000176939.1
Aldh18a1
aldehyde dehydrogenase 18 family, member A1
chr4_-_133967893 4.334 ENSMUST00000100472.3
ENSMUST00000136327.1
Hmgn2

high mobility group nucleosomal binding domain 2

chr1_-_87156127 4.130 ENSMUST00000160810.1
Ecel1
endothelin converting enzyme-like 1
chr11_+_69914179 4.115 ENSMUST00000057884.5
Gps2
G protein pathway suppressor 2
chr9_+_124102110 4.094 ENSMUST00000168841.1
ENSMUST00000055918.6
Ccr2

chemokine (C-C motif) receptor 2

chr18_+_11633276 4.054 ENSMUST00000115861.2
Rbbp8
retinoblastoma binding protein 8
chr7_-_45333754 3.896 ENSMUST00000042194.8
Trpm4
transient receptor potential cation channel, subfamily M, member 4
chr3_-_55055038 3.813 ENSMUST00000029368.2
Ccna1
cyclin A1
chr11_+_3895223 3.787 ENSMUST00000055931.4
ENSMUST00000109996.1
Dusp18

dual specificity phosphatase 18

chr8_+_69822429 3.774 ENSMUST00000164890.1
ENSMUST00000034325.4
Lpar2

lysophosphatidic acid receptor 2

chr14_-_73325773 3.723 ENSMUST00000022701.6
Rb1
retinoblastoma 1
chr2_-_168010618 3.712 ENSMUST00000099073.2
Fam65c
family with sequence similarity 65, member C
chr14_-_76556662 3.623 ENSMUST00000064517.7
Serp2
stress-associated endoplasmic reticulum protein family member 2
chr1_-_52190901 3.601 ENSMUST00000156887.1
ENSMUST00000129107.1
Gls

glutaminase

chr2_+_26628441 3.543 ENSMUST00000074240.3
Fam69b
family with sequence similarity 69, member B
chr15_-_73184840 3.443 ENSMUST00000044113.10
Ago2
argonaute RISC catalytic subunit 2
chr9_+_50856924 3.421 ENSMUST00000174628.1
ENSMUST00000034560.7
ENSMUST00000114437.2
ENSMUST00000175645.1
ENSMUST00000176349.1
ENSMUST00000176798.1
ENSMUST00000175640.1
Ppp2r1b






protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform






chrX_-_37085402 3.370 ENSMUST00000115231.3
Rpl39
ribosomal protein L39
chr18_+_60925612 3.330 ENSMUST00000102888.3
ENSMUST00000025519.4
Camk2a

calcium/calmodulin-dependent protein kinase II alpha

chr14_+_75136475 3.262 ENSMUST00000122840.1
Lcp1
lymphocyte cytosolic protein 1
chr4_-_116167591 3.230 ENSMUST00000030465.3
ENSMUST00000143426.1
Tspan1

tetraspanin 1

chr4_-_133967953 3.210 ENSMUST00000102553.4
Hmgn2
high mobility group nucleosomal binding domain 2
chr11_+_50376982 3.153 ENSMUST00000109142.1
Hnrnph1
heterogeneous nuclear ribonucleoprotein H1
chr3_+_122729158 3.122 ENSMUST00000066728.5
Pde5a
phosphodiesterase 5A, cGMP-specific
chrX_-_75130914 3.099 ENSMUST00000114091.1
Mpp1
membrane protein, palmitoylated
chr9_+_124101944 3.089 ENSMUST00000171719.1
Ccr2
chemokine (C-C motif) receptor 2
chr19_-_38043559 3.056 ENSMUST00000041475.8
ENSMUST00000172095.2
Myof

myoferlin

chrX_-_75130996 2.967 ENSMUST00000033775.2
Mpp1
membrane protein, palmitoylated
chr15_-_79164477 2.942 ENSMUST00000040019.4
Sox10
SRY-box containing gene 10
chr17_-_24527925 2.927 ENSMUST00000176652.1
Traf7
TNF receptor-associated factor 7
chrX_+_6779306 2.901 ENSMUST00000067410.7
Dgkk
diacylglycerol kinase kappa
chr16_-_32810477 2.832 ENSMUST00000179384.2
Gm933
predicted gene 933
chr17_-_24527830 2.811 ENSMUST00000176353.1
ENSMUST00000176237.1
Traf7

TNF receptor-associated factor 7

chr1_-_149961230 2.788 ENSMUST00000070200.8
Pla2g4a
phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr19_-_60861390 2.693 ENSMUST00000135808.1
Sfxn4
sideroflexin 4
chr2_-_51934943 2.691 ENSMUST00000102767.1
ENSMUST00000102768.1
Rbm43

RNA binding motif protein 43

chr3_-_102964124 2.570 ENSMUST00000058899.8
Nr1h5
nuclear receptor subfamily 1, group H, member 5
chr8_+_120488416 2.546 ENSMUST00000034279.9
Gse1
genetic suppressor element 1
chr1_+_58210397 2.515 ENSMUST00000040442.5
Aox4
aldehyde oxidase 4
chr10_+_80019621 2.496 ENSMUST00000043311.6
Hmha1
histocompatibility (minor) HA-1
chr2_+_84798828 2.469 ENSMUST00000102642.2
ENSMUST00000150325.1
Ube2l6

ubiquitin-conjugating enzyme E2L 6

chr2_-_180334665 2.450 ENSMUST00000015771.2
Gata5
GATA binding protein 5
chr5_-_129787175 2.419 ENSMUST00000031399.6
Psph
phosphoserine phosphatase
chr8_-_110846770 2.403 ENSMUST00000042012.5
Sf3b3
splicing factor 3b, subunit 3
chrX_+_56779437 2.402 ENSMUST00000114773.3
Fhl1
four and a half LIM domains 1
chr5_+_114786045 2.396 ENSMUST00000137519.1
Ankrd13a
ankyrin repeat domain 13a
chr11_+_48800357 2.384 ENSMUST00000020640.7
Gnb2l1
guanine nucleotide binding protein (G protein), beta polypeptide 2 like 1
chr8_+_121730563 2.312 ENSMUST00000026357.5
Jph3
junctophilin 3
chr6_+_122990367 2.287 ENSMUST00000079379.2
Clec4a4
C-type lectin domain family 4, member a4
chr13_-_76018524 2.285 ENSMUST00000050997.1
ENSMUST00000179078.1
ENSMUST00000167271.1
Rfesd


Rieske (Fe-S) domain containing


chr10_+_127048235 2.258 ENSMUST00000165764.1
Cyp27b1
cytochrome P450, family 27, subfamily b, polypeptide 1
chr17_+_35059035 2.210 ENSMUST00000007255.6
ENSMUST00000174493.1
Ddah2

dimethylarginine dimethylaminohydrolase 2

chr15_-_100424208 2.201 ENSMUST00000154331.1
Slc11a2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr3_+_95622236 2.193 ENSMUST00000074353.4
Rps10-ps1
ribosomal protein S10, pseudogene 1
chr19_-_29367294 2.164 ENSMUST00000138051.1
Plgrkt
plasminogen receptor, C-terminal lysine transmembrane protein
chr14_+_75136326 2.143 ENSMUST00000145303.1
Lcp1
lymphocyte cytosolic protein 1
chr19_-_36919606 2.109 ENSMUST00000057337.7
Fgfbp3
fibroblast growth factor binding protein 3
chr1_-_133690100 2.099 ENSMUST00000169295.1
Lax1
lymphocyte transmembrane adaptor 1
chr16_-_3907651 2.092 ENSMUST00000177221.1
ENSMUST00000177323.1
1700037C18Rik

RIKEN cDNA 1700037C18 gene

chr7_-_35396708 2.085 ENSMUST00000154597.1
ENSMUST00000032704.5
C230052I12Rik

RIKEN cDNA C230052I12 gene

chr15_-_11905609 2.082 ENSMUST00000066529.3
Npr3
natriuretic peptide receptor 3
chr4_+_115088708 1.987 ENSMUST00000171877.1
ENSMUST00000177647.1
ENSMUST00000106548.2
ENSMUST00000030488.2
Pdzk1ip1



PDZK1 interacting protein 1



chr19_+_34100943 1.952 ENSMUST00000025685.6
Lipm
lipase, family member M
chr1_+_44551483 1.937 ENSMUST00000074525.3
Gulp1
GULP, engulfment adaptor PTB domain containing 1
chr5_-_30073554 1.932 ENSMUST00000026846.6
Tyms
thymidylate synthase
chr17_+_34593388 1.908 ENSMUST00000174532.1
Pbx2
pre B cell leukemia homeobox 2
chr15_-_100424092 1.894 ENSMUST00000154676.1
Slc11a2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr7_+_141447645 1.888 ENSMUST00000106004.1
ENSMUST00000106003.1
Rplp2

ribosomal protein, large P2

chr2_-_148443543 1.844 ENSMUST00000099269.3
Cd93
CD93 antigen
chr11_-_45955465 1.837 ENSMUST00000011398.6
Thg1l
tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
chr14_-_54994541 1.820 ENSMUST00000153783.1
ENSMUST00000168485.1
ENSMUST00000102803.3
Myh7


myosin, heavy polypeptide 7, cardiac muscle, beta


chr1_+_165302625 1.782 ENSMUST00000111450.1
Gpr161
G protein-coupled receptor 161
chr9_-_21037775 1.780 ENSMUST00000180870.1
Gm26592
predicted gene, 26592
chr12_+_78861693 1.747 ENSMUST00000071230.7
Eif2s1
eukaryotic translation initiation factor 2, subunit 1 alpha
chr9_-_109234754 1.700 ENSMUST00000079548.6
Fbxw20
F-box and WD-40 domain protein 20
chrX_-_10216437 1.689 ENSMUST00000115534.1
Rpgr
retinitis pigmentosa GTPase regulator
chr7_+_131032061 1.661 ENSMUST00000084509.3
Dmbt1
deleted in malignant brain tumors 1
chr5_-_100500592 1.647 ENSMUST00000149714.1
ENSMUST00000046154.5
Lin54

lin-54 homolog (C. elegans)

chr14_+_30479565 1.643 ENSMUST00000022535.7
Dcp1a
DCP1 decapping enzyme homolog A (S. cerevisiae)
chr8_-_35826435 1.631 ENSMUST00000060128.5
Cldn23
claudin 23
chr18_+_65582390 1.558 ENSMUST00000169679.1
ENSMUST00000183326.1
Zfp532

zinc finger protein 532

chr19_+_29367447 1.554 ENSMUST00000016640.7
Cd274
CD274 antigen
chr17_+_7170101 1.538 ENSMUST00000024575.6
Rps6ka2
ribosomal protein S6 kinase, polypeptide 2
chr11_+_3289880 1.500 ENSMUST00000110043.1
ENSMUST00000094471.3
Patz1

POZ (BTB) and AT hook containing zinc finger 1

chr11_-_45955183 1.497 ENSMUST00000109254.1
Thg1l
tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
chr6_-_57844493 1.494 ENSMUST00000081186.3
Vmn1r21
vomeronasal 1 receptor 21
chr3_+_92365178 1.486 ENSMUST00000050397.1
Sprr2f
small proline-rich protein 2F
chr18_+_65582239 1.470 ENSMUST00000182684.1
Zfp532
zinc finger protein 532
chrX_+_7841800 1.464 ENSMUST00000033494.9
ENSMUST00000115666.1
Otud5

OTU domain containing 5

chr2_+_16356744 1.458 ENSMUST00000114703.3
Plxdc2
plexin domain containing 2
chr19_-_55241236 1.434 ENSMUST00000069183.6
Gucy2g
guanylate cyclase 2g
chr7_+_113514085 1.387 ENSMUST00000122890.1
Far1
fatty acyl CoA reductase 1
chrX_+_74254736 1.341 ENSMUST00000096424.4
Emd
emerin
chr6_-_92244645 1.329 ENSMUST00000006046.4
Trh
thyrotropin releasing hormone
chr11_-_96111962 1.323 ENSMUST00000097162.5
ENSMUST00000068686.6
Calcoco2

calcium binding and coiled-coil domain 2

chr7_-_126200413 1.310 ENSMUST00000163959.1
Xpo6
exportin 6
chrX_-_7572843 1.304 ENSMUST00000132788.1
Ppp1r3f
protein phosphatase 1, regulatory (inhibitor) subunit 3F
chr5_-_110343009 1.294 ENSMUST00000058016.9
ENSMUST00000112478.3
P2rx2

purinergic receptor P2X, ligand-gated ion channel, 2

chr7_+_35397046 1.284 ENSMUST00000079414.5
Cep89
centrosomal protein 89
chr7_-_126594941 1.281 ENSMUST00000058429.5
Il27
interleukin 27
chr19_+_5568002 1.210 ENSMUST00000096318.3
Ap5b1
adaptor-related protein complex 5, beta 1 subunit
chr2_+_127854628 1.203 ENSMUST00000028859.1
Acoxl
acyl-Coenzyme A oxidase-like
chrX_+_56346390 1.190 ENSMUST00000101560.3
Zfp449
zinc finger protein 449
chr1_-_162740540 1.168 ENSMUST00000028016.9
ENSMUST00000182660.1
Prrc2c

proline-rich coiled-coil 2C

chr9_-_99358518 1.148 ENSMUST00000042158.6
Esyt3
extended synaptotagmin-like protein 3
chr4_-_153482768 1.136 ENSMUST00000105646.2
Ajap1
adherens junction associated protein 1
chr10_-_130127055 1.113 ENSMUST00000074161.1
Olfr824
olfactory receptor 824
chr11_-_78751656 1.091 ENSMUST00000059468.4
Fam58b
family with sequence similarity 58, member B
chr14_-_79481268 1.046 ENSMUST00000022601.5
Wbp4
WW domain binding protein 4
chrX_+_138914422 1.039 ENSMUST00000064937.7
ENSMUST00000113052.1
Nrk

Nik related kinase

chr9_+_35423582 1.029 ENSMUST00000154652.1
Cdon
cell adhesion molecule-related/down-regulated by oncogenes
chr8_-_60954726 1.028 ENSMUST00000110302.1
Clcn3
chloride channel 3
chr6_-_116716888 1.010 ENSMUST00000056623.6
Tmem72
transmembrane protein 72
chr5_+_145114280 0.998 ENSMUST00000141602.1
Arpc1b
actin related protein 2/3 complex, subunit 1B
chr1_-_85109846 0.994 ENSMUST00000161675.1
ENSMUST00000160792.1
A530032D15Rik

RIKEN cDNA A530032D15Rik gene

chr3_-_41742471 0.994 ENSMUST00000026866.8
Sclt1
sodium channel and clathrin linker 1
chr15_-_75909319 0.991 ENSMUST00000089680.3
ENSMUST00000141268.1
ENSMUST00000023235.6
ENSMUST00000109972.2
ENSMUST00000089681.5
ENSMUST00000109975.3
ENSMUST00000154584.1
Eef1d






eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)






chrX_-_48594373 0.988 ENSMUST00000088898.4
ENSMUST00000072292.5
Zfp280c

zinc finger protein 280C

chr15_-_75909289 0.964 ENSMUST00000145764.1
ENSMUST00000116440.2
ENSMUST00000151066.1
Eef1d


eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)


chrX_+_74254679 0.964 ENSMUST00000002029.6
Emd
emerin
chr2_-_154769932 0.939 ENSMUST00000184654.1
Gm14214
predicted gene 14214
chr17_+_34972687 0.918 ENSMUST00000007248.3
Hspa1l
heat shock protein 1-like
chrX_+_7842056 0.888 ENSMUST00000115667.3
ENSMUST00000115668.3
ENSMUST00000115665.1
Otud5


OTU domain containing 5


chr3_+_84952146 0.886 ENSMUST00000029727.7
Fbxw7
F-box and WD-40 domain protein 7
chr15_-_85578070 0.882 ENSMUST00000109424.2
Wnt7b
wingless-related MMTV integration site 7B
chr2_+_163225363 0.871 ENSMUST00000099110.3
ENSMUST00000165937.1
Tox2

TOX high mobility group box family member 2

chr6_-_34317442 0.863 ENSMUST00000154655.1
ENSMUST00000102980.4
Akr1b3

aldo-keto reductase family 1, member B3 (aldose reductase)

chr8_+_33599608 0.862 ENSMUST00000009774.9
Ppp2cb
protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform
chr17_-_65884902 0.847 ENSMUST00000024905.9
Ralbp1
ralA binding protein 1
chr2_-_25983056 0.825 ENSMUST00000127823.1
ENSMUST00000134882.1
Camsap1

calmodulin regulated spectrin-associated protein 1

chr11_-_70969953 0.821 ENSMUST00000108530.1
ENSMUST00000035283.4
ENSMUST00000108531.1
Nup88


nucleoporin 88


chrX_+_52912232 0.813 ENSMUST00000078944.6
ENSMUST00000101587.3
ENSMUST00000154864.2
Phf6


PHD finger protein 6


chrX_+_74254782 0.811 ENSMUST00000119197.1
ENSMUST00000088313.4
Emd

emerin

chr7_-_126200474 0.796 ENSMUST00000168189.1
Xpo6
exportin 6
chr11_-_82829024 0.792 ENSMUST00000021036.6
ENSMUST00000074515.4
ENSMUST00000103218.2
Rffl


ring finger and FYVE like domain containing protein


chr19_-_45749563 0.778 ENSMUST00000070215.7
Npm3
nucleoplasmin 3
chr4_-_132422394 0.743 ENSMUST00000152271.1
ENSMUST00000084170.5
Phactr4

phosphatase and actin regulator 4

chr18_+_65582281 0.700 ENSMUST00000183319.1
Zfp532
zinc finger protein 532
chr15_+_54745702 0.692 ENSMUST00000050027.8
Nov
nephroblastoma overexpressed gene
chr11_+_102885160 0.686 ENSMUST00000100369.3
Fam187a
family with sequence similarity 187, member A
chr9_+_32372409 0.649 ENSMUST00000047334.8
Kcnj1
potassium inwardly-rectifying channel, subfamily J, member 1
chr19_+_6909692 0.623 ENSMUST00000088257.7
Trmt112
tRNA methyltransferase 11-2
chr10_+_62449489 0.615 ENSMUST00000181110.1
4930507D05Rik
RIKEN cDNA 4930507D05 gene
chr16_+_44139821 0.609 ENSMUST00000159514.1
ENSMUST00000161326.1
ENSMUST00000063520.8
ENSMUST00000063542.7
Naa50



N(alpha)-acetyltransferase 50, NatE catalytic subunit



chr4_-_139352538 0.608 ENSMUST00000102503.3
Mrto4
MRT4, mRNA turnover 4, homolog (S. cerevisiae)
chr4_-_141598206 0.605 ENSMUST00000131317.1
ENSMUST00000006381.4
ENSMUST00000129602.1
Fblim1


filamin binding LIM protein 1


chr9_-_109626059 0.604 ENSMUST00000073962.6
Fbxw24
F-box and WD-40 domain protein 24
chr8_+_11556061 0.601 ENSMUST00000054399.4
Ing1
inhibitor of growth family, member 1
chr7_+_101969796 0.598 ENSMUST00000084852.5
Numa1
nuclear mitotic apparatus protein 1
chr8_+_82863351 0.568 ENSMUST00000078525.5
Rnf150
ring finger protein 150
chr11_+_22990519 0.566 ENSMUST00000173867.1
ENSMUST00000020562.4
Cct4

chaperonin containing Tcp1, subunit 4 (delta)


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
4.6 13.8 GO:0006592 ornithine biosynthetic process(GO:0006592)
4.2 12.6 GO:0002842 positive regulation of T cell mediated immune response to tumor cell(GO:0002842)
3.5 10.4 GO:0070488 neutrophil aggregation(GO:0070488)
3.3 9.8 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
2.8 13.9 GO:0071105 response to interleukin-11(GO:0071105)
2.5 12.3 GO:0032289 central nervous system myelin formation(GO:0032289)
2.4 7.2 GO:1902567 immune complex clearance by monocytes and macrophages(GO:0002436) astrocyte chemotaxis(GO:0035700) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) positive regulation of immune complex clearance by monocytes and macrophages(GO:0090265) negative regulation of eosinophil activation(GO:1902567) positive regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000451) regulation of astrocyte chemotaxis(GO:2000458)
2.3 16.0 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
2.3 6.8 GO:0043987 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) histone H3-S10 phosphorylation(GO:0043987)
2.1 16.6 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
1.9 11.3 GO:0019371 cyclooxygenase pathway(GO:0019371)
1.9 13.0 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
1.8 10.9 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
1.3 3.9 GO:0086047 membrane depolarization during Purkinje myocyte cell action potential(GO:0086047)
1.2 3.7 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922) regulation of protein localization to chromatin(GO:1905634)
1.2 4.8 GO:0002030 inhibitory G-protein coupled receptor phosphorylation(GO:0002030)
1.1 5.7 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.9 3.4 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.8 4.1 GO:0015676 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.8 4.1 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.8 3.1 GO:1905881 positive regulation of oocyte development(GO:0060282) positive regulation of oogenesis(GO:1905881)
0.7 12.2 GO:0030953 astral microtubule organization(GO:0030953)
0.7 5.7 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.7 7.3 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.6 5.1 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.6 3.6 GO:0006543 glutamine catabolic process(GO:0006543)
0.6 2.4 GO:1905077 negative regulation of interleukin-17 secretion(GO:1905077)
0.6 2.3 GO:0010980 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980) positive regulation of response to extracellular stimulus(GO:0032106) positive regulation of response to nutrient levels(GO:0032109)
0.6 2.8 GO:0031394 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.5 2.5 GO:0009115 xanthine catabolic process(GO:0009115)
0.5 2.9 GO:0010626 negative regulation of Schwann cell proliferation(GO:0010626)
0.5 2.4 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.5 1.9 GO:0046073 dTMP biosynthetic process(GO:0006231) dTMP metabolic process(GO:0046073)
0.5 6.6 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.4 1.7 GO:0072061 inner medullary collecting duct development(GO:0072061)
0.4 13.3 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.4 3.3 GO:0099004 calmodulin dependent kinase signaling pathway(GO:0099004)
0.4 10.6 GO:0045109 intermediate filament organization(GO:0045109)
0.4 1.8 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724) slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.3 1.0 GO:0070476 rRNA (guanine-N7)-methylation(GO:0070476)
0.3 1.0 GO:0060722 spongiotrophoblast cell proliferation(GO:0060720) cell proliferation involved in embryonic placenta development(GO:0060722)
0.3 1.0 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
0.3 1.7 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.3 1.7 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.3 2.3 GO:0042126 nitrate metabolic process(GO:0042126)
0.3 1.1 GO:0030860 regulation of polarized epithelial cell differentiation(GO:0030860)
0.3 1.3 GO:0001692 histamine metabolic process(GO:0001692)
0.3 2.1 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.3 5.4 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.2 2.2 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.2 2.1 GO:0002158 osteoclast proliferation(GO:0002158)
0.2 1.4 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.2 0.7 GO:1904057 negative regulation of SMAD protein import into nucleus(GO:0060392) endothelial cell-cell adhesion(GO:0071603) negative regulation of sensory perception of pain(GO:1904057) bone regeneration(GO:1990523)
0.2 2.2 GO:0000052 citrulline metabolic process(GO:0000052)
0.2 5.7 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.2 0.6 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979)
0.2 1.6 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.2 3.1 GO:0001778 plasma membrane repair(GO:0001778)
0.2 0.8 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.2 3.1 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.2 3.4 GO:0002227 innate immune response in mucosa(GO:0002227)
0.2 1.6 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.2 6.1 GO:0090022 regulation of neutrophil chemotaxis(GO:0090022)
0.2 1.8 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.2 2.9 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.2 1.5 GO:0002035 brain renin-angiotensin system(GO:0002035)
0.2 9.5 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.2 0.6 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.1 1.0 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.1 1.3 GO:0030432 peristalsis(GO:0030432)
0.1 1.3 GO:0045625 regulation of T-helper 1 cell differentiation(GO:0045625)
0.1 4.5 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.1 2.3 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.1 1.0 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 4.7 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 2.5 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.1 4.1 GO:0003016 respiratory system process(GO:0003016)
0.1 0.9 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 0.6 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.1 1.1 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.1 0.4 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.1 1.3 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465)
0.1 0.3 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 1.7 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 3.8 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.1 2.3 GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.1 4.1 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.1 0.5 GO:0090306 spindle assembly involved in meiosis(GO:0090306)
0.1 0.5 GO:0019348 dolichol metabolic process(GO:0019348)
0.1 1.0 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.1 1.2 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1 2.4 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.1 5.7 GO:0006073 glycogen metabolic process(GO:0005977) cellular glucan metabolic process(GO:0006073) glucan metabolic process(GO:0044042)
0.0 0.2 GO:0048286 lung alveolus development(GO:0048286)
0.0 0.3 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.4 GO:0006498 N-terminal protein lipidation(GO:0006498)
0.0 1.5 GO:0019236 response to pheromone(GO:0019236)
0.0 1.4 GO:0031424 keratinization(GO:0031424)
0.0 0.6 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.3 GO:1904867 protein localization to nuclear body(GO:1903405) positive regulation of establishment of protein localization to telomere(GO:1904851) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173)
0.0 1.9 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 1.7 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 2.7 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 2.6 GO:0071479 cellular response to ionizing radiation(GO:0071479)
0.0 0.1 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.5 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.9 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 0.2 GO:1901911 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 1.1 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 1.4 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.0 0.5 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.8 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.0 GO:0051466 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) positive regulation of isotype switching to IgE isotypes(GO:0048295) positive regulation of corticotropin-releasing hormone secretion(GO:0051466)
0.0 0.9 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.2 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 1.2 GO:0001775 cell activation(GO:0001775)
0.0 1.6 GO:0042177 negative regulation of protein catabolic process(GO:0042177)
0.0 1.3 GO:1905515 non-motile cilium assembly(GO:1905515)
0.0 0.3 GO:0019363 pyridine nucleotide biosynthetic process(GO:0019363)
0.0 2.2 GO:0050821 protein stabilization(GO:0050821)
0.0 1.0 GO:0006400 tRNA modification(GO:0006400)
0.0 0.7 GO:0006911 phagocytosis, engulfment(GO:0006911)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 6.8 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
1.6 9.8 GO:0032133 chromosome passenger complex(GO:0032133)
1.3 6.6 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
1.0 7.3 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.9 4.7 GO:1990769 proximal neuron projection(GO:1990769)
0.8 4.1 GO:0070826 paraferritin complex(GO:0070826)
0.7 3.7 GO:0035189 Rb-E2F complex(GO:0035189)
0.7 3.3 GO:0099524 region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524)
0.6 3.8 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.6 5.1 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.5 12.6 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.4 4.9 GO:0005642 annulate lamellae(GO:0005642)
0.4 1.7 GO:0097450 astrocyte end-foot(GO:0097450)
0.4 2.4 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.4 3.4 GO:0070578 RISC-loading complex(GO:0070578)
0.3 1.0 GO:0036284 tubulobulbar complex(GO:0036284)
0.3 3.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.3 2.3 GO:0030314 junctional membrane complex(GO:0030314)
0.2 1.7 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.2 0.9 GO:0097454 Schwann cell microvillus(GO:0097454)
0.2 10.9 GO:0045171 intercellular bridge(GO:0045171)
0.2 5.4 GO:0001891 phagocytic cup(GO:0001891)
0.2 0.9 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 0.6 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.1 3.9 GO:0034706 sodium channel complex(GO:0034706)
0.1 0.5 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1 5.7 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 1.6 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.1 1.1 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.1 1.8 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.1 2.8 GO:0042588 zymogen granule(GO:0042588)
0.1 1.0 GO:0071439 clathrin complex(GO:0071439)
0.1 4.9 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 9.6 GO:0005882 intermediate filament(GO:0005882)
0.1 1.3 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 1.0 GO:0042581 specific granule(GO:0042581)
0.1 1.1 GO:0044232 organelle membrane contact site(GO:0044232)
0.1 0.6 GO:0031415 NatA complex(GO:0031415)
0.1 1.8 GO:0005859 muscle myosin complex(GO:0005859) myosin filament(GO:0032982)
0.1 5.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 13.0 GO:0000793 condensed chromosome(GO:0000793)
0.1 1.8 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.1 1.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 7.1 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.0 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.0 1.5 GO:0001533 cornified envelope(GO:0001533)
0.0 0.5 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.9 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 3.1 GO:0005901 caveola(GO:0005901)
0.0 1.7 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 1.3 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.3 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 1.2 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 3.2 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 4.6 GO:0031225 anchored component of membrane(GO:0031225)
0.0 3.7 GO:0030139 endocytic vesicle(GO:0030139)
0.0 5.3 GO:0008021 synaptic vesicle(GO:0008021)
0.0 35.1 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 0.7 GO:0005921 gap junction(GO:0005921)
0.0 0.2 GO:0036501 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) UFD1-NPL4 complex(GO:0036501)
0.0 1.8 GO:0055037 recycling endosome(GO:0055037)
0.0 1.2 GO:0016020 membrane(GO:0016020)
0.0 1.5 GO:0005819 spindle(GO:0005819)
0.0 4.9 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 1.7 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 1.6 GO:0030863 cortical cytoskeleton(GO:0030863)
0.0 0.8 GO:0005643 nuclear pore(GO:0005643)
0.0 1.0 GO:0043234 protein complex(GO:0043234)
0.0 5.6 GO:0005813 centrosome(GO:0005813)
0.0 0.8 GO:0000776 kinetochore(GO:0000776)
0.0 10.7 GO:0030054 cell junction(GO:0030054)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.6 13.8 GO:0017084 glutamate 5-kinase activity(GO:0004349) glutamate-5-semialdehyde dehydrogenase activity(GO:0004350) delta1-pyrroline-5-carboxylate synthetase activity(GO:0017084) amino acid kinase activity(GO:0019202)
3.3 26.4 GO:0050786 RAGE receptor binding(GO:0050786)
2.4 7.2 GO:0035717 chemokine (C-C motif) ligand 7 binding(GO:0035717)
2.1 16.6 GO:0002951 leukotriene-C(4) hydrolase(GO:0002951)
1.7 6.8 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
1.6 11.3 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
1.3 6.6 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
1.1 3.3 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.9 13.9 GO:0050693 LBD domain binding(GO:0050693)
0.8 4.1 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.8 2.4 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.8 12.6 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.8 2.3 GO:0098809 nitrite reductase activity(GO:0098809)
0.7 11.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.6 3.6 GO:0004359 glutaminase activity(GO:0004359)
0.5 9.8 GO:0035174 histone serine kinase activity(GO:0035174)
0.5 1.5 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.5 2.5 GO:0016623 aldehyde oxidase activity(GO:0004031) xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726)
0.5 4.9 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.5 4.2 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.5 5.1 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.4 2.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.4 2.3 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.3 3.4 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.3 1.3 GO:2001069 glycogen binding(GO:2001069)
0.3 1.3 GO:0046870 cadmium ion binding(GO:0046870)
0.3 2.8 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.3 2.4 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.3 4.1 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.3 1.4 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.3 1.0 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.2 2.6 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.2 1.9 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.2 1.8 GO:0001849 complement component C1q binding(GO:0001849)
0.2 2.9 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.2 0.9 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
0.2 2.2 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.2 12.5 GO:0015485 cholesterol binding(GO:0015485)
0.2 12.3 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.2 0.9 GO:0050816 phosphothreonine residue binding(GO:0050816)
0.2 1.9 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.2 5.7 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.2 0.9 GO:0042296 ISG15 transferase activity(GO:0042296)
0.1 1.0 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.1 3.1 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.1 0.6 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 0.5 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.1 1.2 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.1 0.4 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 5.7 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 2.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.9 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.1 10.8 GO:0005179 hormone activity(GO:0005179)
0.1 1.8 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 0.3 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.1 2.3 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.1 0.5 GO:0048039 ubiquinone binding(GO:0048039)
0.1 10.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 2.9 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 0.6 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 2.3 GO:0008536 Ran GTPase binding(GO:0008536)
0.1 1.5 GO:0016503 pheromone receptor activity(GO:0016503)
0.1 0.8 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 0.3 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.1 2.4 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.1 1.8 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 1.1 GO:0070064 proline-rich region binding(GO:0070064)
0.0 2.6 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.5 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 2.1 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.8 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.6 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 1.4 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 1.1 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.3 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.0 1.7 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.1 GO:0004568 chitinase activity(GO:0004568)
0.0 1.7 GO:0043022 ribosome binding(GO:0043022)
0.0 0.2 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.0 5.3 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.7 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.6 GO:0031005 filamin binding(GO:0031005)
0.0 0.8 GO:0030507 spectrin binding(GO:0030507)
0.0 1.0 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 1.0 GO:0005549 odorant binding(GO:0005549)
0.0 6.7 GO:0005198 structural molecule activity(GO:0005198)
0.0 3.4 GO:0051015 actin filament binding(GO:0051015)
0.0 1.8 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.6 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 2.4 GO:0044325 ion channel binding(GO:0044325)
0.0 5.2 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 2.5 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.9 GO:0051082 unfolded protein binding(GO:0051082)
0.0 3.0 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 9.5 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.8 GO:0097110 scaffold protein binding(GO:0097110)
0.0 1.1 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.9 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.6 GO:0019894 kinesin binding(GO:0019894)
0.0 0.6 GO:0140034 methylated histone binding(GO:0035064) methylation-dependent protein binding(GO:0140034)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 21.4 PID_AURORA_A_PATHWAY Aurora A signaling
0.5 3.8 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.4 11.3 PID_S1P_META_PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.3 4.9 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.3 10.4 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.2 10.5 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.2 10.8 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.2 2.4 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.2 12.0 PID_E2F_PATHWAY E2F transcription factor network
0.1 15.6 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 9.0 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.1 1.3 PID_IL27_PATHWAY IL27-mediated signaling events
0.1 3.3 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 4.3 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 2.8 PID_ENDOTHELIN_PATHWAY Endothelins
0.1 3.8 PID_LYSOPHOSPHOLIPID_PATHWAY LPA receptor mediated events
0.0 0.9 PID_MYC_PATHWAY C-MYC pathway
0.0 2.0 PID_VEGFR1_2_PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.9 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 1.5 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.0 0.7 PID_ARF6_PATHWAY Arf6 signaling events
0.0 0.4 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.5 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.0 0.9 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.0 1.0 PID_CDC42_PATHWAY CDC42 signaling events
0.0 0.6 PID_CASPASE_PATHWAY Caspase cascade in apoptosis

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 7.2 REACTOME_BETA_DEFENSINS Genes involved in Beta defensins
1.0 16.0 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.9 15.5 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.7 8.0 REACTOME_INHIBITION_OF_REPLICATION_INITIATION_OF_DAMAGED_DNA_BY_RB1_E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.6 8.0 REACTOME_G1_S_SPECIFIC_TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.5 12.8 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.4 16.6 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.4 9.8 REACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX Genes involved in Activation of the pre-replicative complex
0.3 12.3 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 2.8 REACTOME_ACYL_CHAIN_REMODELLING_OF_PI Genes involved in Acyl chain remodelling of PI
0.1 3.3 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.1 9.8 REACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.1 4.8 REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 1.6 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
0.1 1.6 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 1.6 REACTOME_PD1_SIGNALING Genes involved in PD-1 signaling
0.1 3.1 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.1 9.7 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 2.3 REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 0.6 REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 1.7 REACTOME_PERK_REGULATED_GENE_EXPRESSION Genes involved in PERK regulated gene expression
0.1 2.9 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 0.4 REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE_ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.1 1.7 REACTOME_ERK_MAPK_TARGETS Genes involved in ERK/MAPK targets
0.1 2.4 REACTOME_MRNA_SPLICING_MINOR_PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 5.3 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.0 8.5 REACTOME_G_ALPHA_I_SIGNALLING_EVENTS Genes involved in G alpha (i) signalling events
0.0 3.1 REACTOME_MEIOTIC_RECOMBINATION Genes involved in Meiotic Recombination
0.0 2.9 REACTOME_REGULATION_OF_INSULIN_SECRETION Genes involved in Regulation of Insulin Secretion
0.0 3.2 REACTOME_MRNA_SPLICING Genes involved in mRNA Splicing
0.0 1.0 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 13.8 REACTOME_HEMOSTASIS Genes involved in Hemostasis
0.0 0.5 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.8 REACTOME_TRANSPORT_OF_RIBONUCLEOPROTEINS_INTO_THE_HOST_NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.6 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 4.6 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.6 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates