Motif ID: Tfeb_Usf1_Srebf1_Usf2_Bhlhe41_Srebf2

Z-value: 1.191


Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Srebf2mm10_v2_chr15_+_82147238_821472750.618.7e-05Click!
Srebf1mm10_v2_chr11_-_60220550_60220632-0.563.8e-04Click!
Usf2mm10_v2_chr7_-_30956742_309568030.521.0e-03Click!
Bhlhe41mm10_v2_chr6_-_145865483_1458655580.307.3e-02Click!
Tfebmm10_v2_chr17_+_47737030_477371070.231.7e-01Click!
Usf1mm10_v2_chr1_+_171411343_1714113840.192.7e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Tfeb_Usf1_Srebf1_Usf2_Bhlhe41_Srebf2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_-_136068236 19.015 ENSMUST00000049130.7
Bex2
brain expressed X-linked 2
chrX_-_136215443 13.937 ENSMUST00000113120.1
ENSMUST00000113118.1
ENSMUST00000058125.8
Bex1


brain expressed gene 1


chr9_+_21368014 13.514 ENSMUST00000067646.4
ENSMUST00000115414.1
Ilf3

interleukin enhancer binding factor 3

chrX_+_136270302 10.965 ENSMUST00000113112.1
Ngfrap1
nerve growth factor receptor (TNFRSF16) associated protein 1
chrX_+_136270253 10.776 ENSMUST00000178632.1
ENSMUST00000053540.4
Ngfrap1

nerve growth factor receptor (TNFRSF16) associated protein 1

chr11_+_116198853 10.159 ENSMUST00000021130.6
Ten1
TEN1 telomerase capping complex subunit
chrX_+_136138996 10.153 ENSMUST00000116527.1
Bex4
brain expressed gene 4
chr2_+_30286383 9.656 ENSMUST00000064447.5
Nup188
nucleoporin 188
chr13_+_108316395 9.543 ENSMUST00000171178.1
Depdc1b
DEP domain containing 1B
chr13_+_108316332 9.446 ENSMUST00000051594.5
Depdc1b
DEP domain containing 1B
chr5_-_148995147 8.916 ENSMUST00000147473.1
Katnal1
katanin p60 subunit A-like 1
chr12_-_32061221 8.740 ENSMUST00000003079.5
ENSMUST00000036497.9
Prkar2b

protein kinase, cAMP dependent regulatory, type II beta

chr9_-_22389113 8.278 ENSMUST00000040912.7
Anln
anillin, actin binding protein
chr7_+_90130227 8.196 ENSMUST00000049537.7
Picalm
phosphatidylinositol binding clathrin assembly protein
chr6_-_52217505 8.003 ENSMUST00000048715.6
Hoxa7
homeobox A7
chr3_+_28781305 8.000 ENSMUST00000060500.7
Eif5a2
eukaryotic translation initiation factor 5A2
chrX_-_136203637 7.955 ENSMUST00000151592.1
ENSMUST00000131510.1
ENSMUST00000066819.4
Tceal5


transcription elongation factor A (SII)-like 5


chr3_-_90052463 7.527 ENSMUST00000029553.9
ENSMUST00000064639.8
ENSMUST00000090908.6
Ubap2l


ubiquitin associated protein 2-like


chr19_-_10203880 7.355 ENSMUST00000142241.1
ENSMUST00000116542.2
ENSMUST00000025651.5
ENSMUST00000156291.1
Fen1



flap structure specific endonuclease 1



chr6_+_128362919 7.285 ENSMUST00000073316.6
Foxm1
forkhead box M1
chr3_+_159495408 7.271 ENSMUST00000120272.1
ENSMUST00000029825.7
ENSMUST00000106041.2
Depdc1a


DEP domain containing 1a


chr5_-_136170634 6.996 ENSMUST00000041048.1
Orai2
ORAI calcium release-activated calcium modulator 2
chr1_-_193035651 6.951 ENSMUST00000016344.7
Syt14
synaptotagmin XIV
chr2_+_30286406 6.914 ENSMUST00000138666.1
ENSMUST00000113634.2
Nup188

nucleoporin 188

chr4_-_134018829 6.860 ENSMUST00000051674.2
Lin28a
lin-28 homolog A (C. elegans)
chr11_+_70000578 6.673 ENSMUST00000019362.8
Dvl2
dishevelled 2, dsh homolog (Drosophila)
chr5_+_118560719 6.604 ENSMUST00000100816.4
Med13l
mediator complex subunit 13-like
chr3_+_19644452 6.545 ENSMUST00000029139.7
Trim55
tripartite motif-containing 55
chr8_+_75093591 6.544 ENSMUST00000005548.6
Hmox1
heme oxygenase (decycling) 1
chr14_+_32321987 6.539 ENSMUST00000022480.7
Ogdhl
oxoglutarate dehydrogenase-like
chrX_+_153139941 6.534 ENSMUST00000039720.4
ENSMUST00000144175.2
Rragb

Ras-related GTP binding B

chr10_+_13090788 6.522 ENSMUST00000121646.1
ENSMUST00000121325.1
ENSMUST00000121766.1
Plagl1


pleiomorphic adenoma gene-like 1


chr1_-_75142360 6.321 ENSMUST00000041213.5
Cnppd1
cyclin Pas1/PHO80 domain containing 1
chr19_+_10018265 6.158 ENSMUST00000131407.1
Rab3il1
RAB3A interacting protein (rabin3)-like 1
chr17_-_12769605 6.059 ENSMUST00000024599.7
Igf2r
insulin-like growth factor 2 receptor
chr19_+_10018193 5.972 ENSMUST00000113161.2
ENSMUST00000117641.1
Rab3il1

RAB3A interacting protein (rabin3)-like 1

chrX_+_136224035 5.955 ENSMUST00000113116.2
Tceal7
transcription elongation factor A (SII)-like 7
chr17_-_66077022 5.907 ENSMUST00000150766.1
ENSMUST00000038116.5
Ankrd12

ankyrin repeat domain 12

chr4_-_41275091 5.824 ENSMUST00000030143.6
ENSMUST00000108068.1
Ubap2

ubiquitin-associated protein 2

chr11_+_102881204 5.806 ENSMUST00000021307.3
ENSMUST00000159834.1
Ccdc103

coiled-coil domain containing 103

chr4_-_45084538 5.768 ENSMUST00000052236.6
Fbxo10
F-box protein 10
chrX_-_135210672 5.726 ENSMUST00000033783.1
Tceal6
transcription elongation factor A (SII)-like 6
chr17_-_53689266 5.674 ENSMUST00000024736.7
Sgol1
shugoshin-like 1 (S. pombe)
chr15_-_96642883 5.594 ENSMUST00000088452.4
Slc38a1
solute carrier family 38, member 1
chr17_+_56040350 5.552 ENSMUST00000002914.8
Chaf1a
chromatin assembly factor 1, subunit A (p150)
chr2_+_4300462 5.510 ENSMUST00000175669.1
Frmd4a
FERM domain containing 4A
chr11_-_94653964 5.481 ENSMUST00000039949.4
Eme1
essential meiotic endonuclease 1 homolog 1 (S. pombe)
chr17_-_26199008 5.380 ENSMUST00000142410.1
ENSMUST00000120333.1
ENSMUST00000039113.7
Pdia2


protein disulfide isomerase associated 2


chr2_+_84839395 5.155 ENSMUST00000146816.1
ENSMUST00000028469.7
Slc43a1

solute carrier family 43, member 1

chr15_-_77956658 4.942 ENSMUST00000117725.1
ENSMUST00000016696.6
Foxred2

FAD-dependent oxidoreductase domain containing 2

chr5_+_99979061 4.915 ENSMUST00000046721.1
4930524J08Rik
RIKEN cDNA 4930524J08 gene
chr19_-_4201591 4.893 ENSMUST00000025740.6
Rad9a
RAD9 homolog A
chrX_-_134751331 4.831 ENSMUST00000113194.1
ENSMUST00000052431.5
Armcx6

armadillo repeat containing, X-linked 6

chrX_-_134808984 4.816 ENSMUST00000035559.4
Armcx2
armadillo repeat containing, X-linked 2
chr2_-_74578875 4.786 ENSMUST00000134168.1
ENSMUST00000111993.2
ENSMUST00000064503.6
Lnp


limb and neural patterns


chr7_+_16098458 4.774 ENSMUST00000006181.6
Napa
N-ethylmaleimide sensitive fusion protein attachment protein alpha
chr9_-_42124276 4.722 ENSMUST00000060989.8
Sorl1
sortilin-related receptor, LDLR class A repeats-containing
chr3_-_37724321 4.719 ENSMUST00000108105.1
ENSMUST00000079755.4
ENSMUST00000099128.1
Gm5148


predicted gene 5148


chrX_+_134601179 4.684 ENSMUST00000074950.4
ENSMUST00000113203.1
ENSMUST00000113202.1
Hnrnph2


heterogeneous nuclear ribonucleoprotein H2


chrX_+_136666375 4.643 ENSMUST00000060904.4
ENSMUST00000113100.1
ENSMUST00000128040.1
Tceal3


transcription elongation factor A (SII)-like 3


chr15_+_59374198 4.633 ENSMUST00000079703.3
ENSMUST00000168722.1
Nsmce2

non-SMC element 2 homolog (MMS21, S. cerevisiae)

chr9_+_70679016 4.623 ENSMUST00000144537.1
Adam10
a disintegrin and metallopeptidase domain 10
chr6_+_116338013 4.615 ENSMUST00000079012.6
ENSMUST00000101032.3
March8

membrane-associated ring finger (C3HC4) 8

chr11_+_95337012 4.608 ENSMUST00000037502.6
Fam117a
family with sequence similarity 117, member A
chr11_-_117780630 4.604 ENSMUST00000026659.3
ENSMUST00000127227.1
Tmc6

transmembrane channel-like gene family 6

chr6_-_52217435 4.603 ENSMUST00000140316.1
Hoxa7
homeobox A7
chrX_+_134601271 4.581 ENSMUST00000050331.6
ENSMUST00000059297.5
Hnrnph2

heterogeneous nuclear ribonucleoprotein H2

chrX_+_48146436 4.574 ENSMUST00000033427.6
Sash3
SAM and SH3 domain containing 3
chr7_-_46795661 4.510 ENSMUST00000123725.1
Hps5
Hermansky-Pudlak syndrome 5 homolog (human)
chr15_-_96642311 4.502 ENSMUST00000088454.5
Slc38a1
solute carrier family 38, member 1
chr15_+_73724754 4.495 ENSMUST00000163582.1
Ptp4a3
protein tyrosine phosphatase 4a3
chr9_-_103480328 4.445 ENSMUST00000124310.2
Bfsp2
beaded filament structural protein 2, phakinin
chrX_+_56454871 4.429 ENSMUST00000039374.2
ENSMUST00000101553.2
Ddx26b

DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B

chr4_+_148039035 4.359 ENSMUST00000097788.4
Mthfr
5,10-methylenetetrahydrofolate reductase
chr6_-_88898664 4.324 ENSMUST00000058011.6
Mcm2
minichromosome maintenance deficient 2 mitotin (S. cerevisiae)
chr7_+_35802593 4.294 ENSMUST00000052454.2
E130304I02Rik
RIKEN cDNA E130304I02 gene
chr7_-_45466894 4.239 ENSMUST00000033093.8
Bax
BCL2-associated X protein
chr6_-_52226165 4.202 ENSMUST00000114425.2
Hoxa9
homeobox A9
chr14_-_52197216 4.196 ENSMUST00000046709.7
Supt16
suppressor of Ty 16
chr19_-_4615453 4.156 ENSMUST00000053597.2
Lrfn4
leucine rich repeat and fibronectin type III domain containing 4
chr4_-_49597860 4.040 ENSMUST00000042750.2
Tmem246
transmembrane protein 246
chr9_+_70678950 4.018 ENSMUST00000067880.6
Adam10
a disintegrin and metallopeptidase domain 10
chr2_-_74579379 4.014 ENSMUST00000130586.1
Lnp
limb and neural patterns
chr15_-_89425856 4.008 ENSMUST00000109313.2
Cpt1b
carnitine palmitoyltransferase 1b, muscle
chr2_+_92915080 3.979 ENSMUST00000028648.2
Syt13
synaptotagmin XIII
chr5_+_143622440 3.937 ENSMUST00000116456.3
Cyth3
cytohesin 3
chr11_+_61684419 3.936 ENSMUST00000093019.5
Fam83g
family with sequence similarity 83, member G
chr4_+_130308595 3.925 ENSMUST00000070532.7
Fabp3
fatty acid binding protein 3, muscle and heart
chr16_-_92826004 3.909 ENSMUST00000023673.7
Runx1
runt related transcription factor 1
chr5_-_124425572 3.873 ENSMUST00000168651.1
Sbno1
sno, strawberry notch homolog 1 (Drosophila)
chr6_-_128362812 3.854 ENSMUST00000112152.1
ENSMUST00000057421.8
ENSMUST00000112151.1
Rhno1


RAD9-HUS1-RAD1 interacting nuclear orphan 1


chrX_+_50841434 3.812 ENSMUST00000114887.2
2610018G03Rik
RIKEN cDNA 2610018G03 gene
chr10_+_122678764 3.797 ENSMUST00000161487.1
ENSMUST00000067918.5
Ppm1h

protein phosphatase 1H (PP2C domain containing)

chr5_-_72168142 3.792 ENSMUST00000013693.6
Commd8
COMM domain containing 8
chr4_-_49597425 3.781 ENSMUST00000150664.1
Tmem246
transmembrane protein 246
chr2_-_160619971 3.765 ENSMUST00000109473.1
Gm14221
predicted gene 14221
chr11_+_69913888 3.716 ENSMUST00000072581.2
ENSMUST00000116358.1
Gps2

G protein pathway suppressor 2

chr4_+_148039097 3.708 ENSMUST00000141283.1
Mthfr
5,10-methylenetetrahydrofolate reductase
chr3_+_137864573 3.703 ENSMUST00000174561.1
ENSMUST00000173790.1
H2afz

H2A histone family, member Z

chr5_-_113830422 3.701 ENSMUST00000100874.4
Selplg
selectin, platelet (p-selectin) ligand
chr19_-_7241216 3.686 ENSMUST00000025675.9
Naa40
N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog (S. cerevisiae)
chr5_+_143622466 3.663 ENSMUST00000177196.1
Cyth3
cytohesin 3
chrX_-_136172195 3.655 ENSMUST00000136533.1
ENSMUST00000146583.1
Tceal8

transcription elongation factor A (SII)-like 8

chr2_+_129198757 3.639 ENSMUST00000028880.3
Slc20a1
solute carrier family 20, member 1
chr16_+_35770382 3.617 ENSMUST00000023555.4
Hspbap1
Hspb associated protein 1
chrX_+_106027259 3.563 ENSMUST00000113557.1
Atp7a
ATPase, Cu++ transporting, alpha polypeptide
chr9_-_103761820 3.557 ENSMUST00000049452.8
Tmem108
transmembrane protein 108
chrX_+_106027300 3.522 ENSMUST00000055941.6
Atp7a
ATPase, Cu++ transporting, alpha polypeptide
chr9_-_97111117 3.518 ENSMUST00000085206.4
Slc25a36
solute carrier family 25, member 36
chr2_+_75659253 3.492 ENSMUST00000111964.1
ENSMUST00000111962.1
ENSMUST00000111961.1
ENSMUST00000164947.2
ENSMUST00000090792.4
Hnrnpa3




heterogeneous nuclear ribonucleoprotein A3




chr4_-_45408646 3.470 ENSMUST00000153904.1
ENSMUST00000132815.2
ENSMUST00000107796.1
ENSMUST00000116341.3
Slc25a51



solute carrier family 25, member 51



chr7_-_30821139 3.458 ENSMUST00000163504.1
Ffar2
free fatty acid receptor 2
chrX_+_68678712 3.440 ENSMUST00000114654.1
ENSMUST00000114655.1
ENSMUST00000114657.2
ENSMUST00000114653.1
Fmr1



fragile X mental retardation syndrome 1



chr15_+_102296256 3.410 ENSMUST00000064924.4
Espl1
extra spindle poles-like 1 (S. cerevisiae)
chr3_-_108722281 3.365 ENSMUST00000029482.9
Gpsm2
G-protein signalling modulator 2 (AGS3-like, C. elegans)
chr10_-_62792243 3.364 ENSMUST00000020268.5
Ccar1
cell division cycle and apoptosis regulator 1
chr11_+_69914179 3.333 ENSMUST00000057884.5
Gps2
G protein pathway suppressor 2
chr19_-_4615647 3.315 ENSMUST00000113822.2
Lrfn4
leucine rich repeat and fibronectin type III domain containing 4
chr17_-_33685386 3.310 ENSMUST00000139302.1
ENSMUST00000087582.5
ENSMUST00000114385.2
Hnrnpm


heterogeneous nuclear ribonucleoprotein M


chr6_+_134929118 3.307 ENSMUST00000185152.1
ENSMUST00000184504.1
RP23-45G16.5

RP23-45G16.5

chrX_+_136245065 3.215 ENSMUST00000048687.4
Wbp5
WW domain binding protein 5
chr4_-_116994354 3.210 ENSMUST00000130273.1
Urod
uroporphyrinogen decarboxylase
chr17_+_48359891 3.198 ENSMUST00000024792.6
Treml1
triggering receptor expressed on myeloid cells-like 1
chr10_+_80016901 3.193 ENSMUST00000105373.1
Hmha1
histocompatibility (minor) HA-1
chr6_+_134929089 3.193 ENSMUST00000183867.1
ENSMUST00000184991.1
ENSMUST00000183905.1
RP23-45G16.5


RP23-45G16.5


chr5_-_114773488 3.192 ENSMUST00000178440.1
ENSMUST00000043283.7
ENSMUST00000112185.2
Git2


G protein-coupled receptor kinase-interactor 2


chr10_+_80016653 3.179 ENSMUST00000099501.3
Hmha1
histocompatibility (minor) HA-1
chr15_+_79348061 3.115 ENSMUST00000163691.1
Maff
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)
chr10_+_127063599 3.113 ENSMUST00000120226.1
ENSMUST00000133115.1
Cdk4

cyclin-dependent kinase 4

chr9_-_13826946 3.096 ENSMUST00000147115.1
Cep57
centrosomal protein 57
chr15_-_79834261 3.089 ENSMUST00000148358.1
Cbx6
chromobox 6
chr4_-_148087961 3.076 ENSMUST00000030865.8
Agtrap
angiotensin II, type I receptor-associated protein
chr14_+_52197502 3.063 ENSMUST00000180857.1
Gm26590
predicted gene, 26590
chr11_+_117782358 3.037 ENSMUST00000117781.1
Tmc8
transmembrane channel-like gene family 8
chr11_+_117782076 2.992 ENSMUST00000127080.1
Tmc8
transmembrane channel-like gene family 8
chr10_+_111164794 2.986 ENSMUST00000105275.1
ENSMUST00000095310.1
Osbpl8

oxysterol binding protein-like 8

chr5_-_114773372 2.976 ENSMUST00000112183.1
ENSMUST00000086564.4
Git2

G protein-coupled receptor kinase-interactor 2

chr8_+_85036906 2.949 ENSMUST00000093360.4
Tnpo2
transportin 2 (importin 3, karyopherin beta 2b)
chr16_+_5050012 2.924 ENSMUST00000052449.5
Ubn1
ubinuclein 1
chr6_+_72097561 2.902 ENSMUST00000069994.4
ENSMUST00000114112.1
St3gal5

ST3 beta-galactoside alpha-2,3-sialyltransferase 5

chr3_+_137864487 2.902 ENSMUST00000041045.7
H2afz
H2A histone family, member Z
chr8_+_85037151 2.896 ENSMUST00000166592.1
Tnpo2
transportin 2 (importin 3, karyopherin beta 2b)
chr11_+_117782281 2.894 ENSMUST00000050874.7
ENSMUST00000106334.2
Tmc8

transmembrane channel-like gene family 8

chr10_-_120201558 2.873 ENSMUST00000020448.4
Irak3
interleukin-1 receptor-associated kinase 3
chr16_-_32487873 2.855 ENSMUST00000042042.7
Slc51a
solute carrier family 51, alpha subunit
chr5_-_99978914 2.851 ENSMUST00000112939.3
ENSMUST00000171786.1
ENSMUST00000072750.6
ENSMUST00000019128.8
ENSMUST00000172361.1
Hnrnpd




heterogeneous nuclear ribonucleoprotein D




chr2_-_178414460 2.839 ENSMUST00000058678.4
Ppp1r3d
protein phosphatase 1, regulatory subunit 3D
chr2_+_91035613 2.839 ENSMUST00000111445.3
ENSMUST00000111446.3
ENSMUST00000050323.5
Rapsn


receptor-associated protein of the synapse


chr1_+_82724881 2.837 ENSMUST00000078332.6
Mff
mitochondrial fission factor
chr3_+_153844209 2.827 ENSMUST00000044089.3
Asb17
ankyrin repeat and SOCS box-containing 17
chr4_-_116994374 2.822 ENSMUST00000030446.8
Urod
uroporphyrinogen decarboxylase
chr2_-_150668198 2.810 ENSMUST00000028944.3
Acss1
acyl-CoA synthetase short-chain family member 1
chr14_+_70457447 2.800 ENSMUST00000003561.3
Phyhip
phytanoyl-CoA hydroxylase interacting protein
chr15_-_102510681 2.791 ENSMUST00000171565.1
Map3k12
mitogen-activated protein kinase kinase kinase 12
chr11_-_102880925 2.783 ENSMUST00000021306.7
Eftud2
elongation factor Tu GTP binding domain containing 2
chr15_-_79834224 2.763 ENSMUST00000109623.1
ENSMUST00000109625.1
ENSMUST00000023060.6
ENSMUST00000089299.5
Cbx6

Npcd

chromobox 6

neuronal pentraxin chromo domain

chr11_-_11462408 2.761 ENSMUST00000020413.3
Zpbp
zona pellucida binding protein
chr2_+_158794807 2.761 ENSMUST00000029186.7
ENSMUST00000109478.2
ENSMUST00000156893.1
Dhx35


DEAH (Asp-Glu-Ala-His) box polypeptide 35


chr19_-_8786272 2.760 ENSMUST00000176610.1
ENSMUST00000177056.1
Taf6l

TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor

chrX_-_136172233 2.751 ENSMUST00000163584.1
ENSMUST00000060101.3
Tceal8

transcription elongation factor A (SII)-like 8

chr10_+_119992916 2.749 ENSMUST00000105261.2
Grip1
glutamate receptor interacting protein 1
chr11_+_87127267 2.745 ENSMUST00000139532.1
Trim37
tripartite motif-containing 37
chr19_-_8786245 2.740 ENSMUST00000177216.1
Taf6l
TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor
chr19_+_34922351 2.732 ENSMUST00000087341.5
Kif20b
kinesin family member 20B
chr11_+_114727384 2.726 ENSMUST00000069325.7
Dnaic2
dynein, axonemal, intermediate chain 2
chr10_+_86022189 2.719 ENSMUST00000120344.1
ENSMUST00000117597.1
Fbxo7

F-box protein 7

chr8_+_119575235 2.711 ENSMUST00000093100.2
Dnaaf1
dynein, axonemal assembly factor 1
chr2_+_178414512 2.699 ENSMUST00000094251.4
Fam217b
family with sequence similarity 217, member B
chr1_+_17727034 2.698 ENSMUST00000159958.1
ENSMUST00000160305.1
ENSMUST00000095075.4
Crispld1


cysteine-rich secretory protein LCCL domain containing 1


chr16_-_44139003 2.646 ENSMUST00000124102.1
Atp6v1a
ATPase, H+ transporting, lysosomal V1 subunit A
chr6_-_52158292 2.645 ENSMUST00000000964.5
ENSMUST00000120363.1
Hoxa1

homeobox A1

chr17_-_56476462 2.607 ENSMUST00000067538.5
Ptprs
protein tyrosine phosphatase, receptor type, S
chrX_+_68678541 2.598 ENSMUST00000088546.5
Fmr1
fragile X mental retardation syndrome 1
chr18_+_53176345 2.576 ENSMUST00000037850.5
Snx2
sorting nexin 2
chr2_+_164074122 2.557 ENSMUST00000018353.7
Stk4
serine/threonine kinase 4
chr14_-_67008834 2.550 ENSMUST00000111115.1
ENSMUST00000022634.8
Bnip3l

BCL2/adenovirus E1B interacting protein 3-like

chr4_+_130055010 2.539 ENSMUST00000123617.1
Col16a1
collagen, type XVI, alpha 1
chr3_+_116562965 2.539 ENSMUST00000029573.5
Lrrc39
leucine rich repeat containing 39
chrX_+_134686519 2.524 ENSMUST00000124226.2
Armcx4
armadillo repeat containing, X-linked 4
chr11_-_102880981 2.517 ENSMUST00000107060.1
Eftud2
elongation factor Tu GTP binding domain containing 2
chr10_+_86021961 2.488 ENSMUST00000130320.1
Fbxo7
F-box protein 7
chrX_+_8271381 2.476 ENSMUST00000033512.4
Slc38a5
solute carrier family 38, member 5
chr14_+_80000292 2.472 ENSMUST00000088735.3
Olfm4
olfactomedin 4
chr19_-_8786408 2.461 ENSMUST00000176496.1
Taf6l
TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor
chr19_-_60790692 2.457 ENSMUST00000025955.6
Eif3a
eukaryotic translation initiation factor 3, subunit A
chr1_-_40085823 2.456 ENSMUST00000181756.1
Gm16894
predicted gene, 16894
chr11_-_34783850 2.455 ENSMUST00000093193.5
ENSMUST00000101365.2
Dock2

dedicator of cyto-kinesis 2

chr11_-_96943945 2.453 ENSMUST00000107629.1
ENSMUST00000018803.5
Pnpo

pyridoxine 5'-phosphate oxidase

chr12_-_101958148 2.451 ENSMUST00000159883.1
ENSMUST00000160251.1
ENSMUST00000161011.1
ENSMUST00000021606.5
Atxn3



ataxin 3



chrX_+_8271133 2.449 ENSMUST00000127103.1
ENSMUST00000115591.1
Slc38a5

solute carrier family 38, member 5

chr18_-_12941777 2.447 ENSMUST00000122175.1
Osbpl1a
oxysterol binding protein-like 1A
chr2_+_84980458 2.432 ENSMUST00000028467.5
Prg2
proteoglycan 2, bone marrow
chr16_-_18811615 2.420 ENSMUST00000096990.3
Cdc45
cell division cycle 45
chr4_-_48473403 2.420 ENSMUST00000164866.1
ENSMUST00000030030.8
Tex10

testis expressed gene 10

chr4_-_141053660 2.418 ENSMUST00000040222.7
Crocc
ciliary rootlet coiled-coil, rootletin
chr14_-_104522615 2.408 ENSMUST00000022716.2
Rnf219
ring finger protein 219
chr3_-_153725062 2.385 ENSMUST00000064460.5
St6galnac3
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
chr1_+_82724909 2.376 ENSMUST00000073025.5
ENSMUST00000161648.1
ENSMUST00000160786.1
ENSMUST00000162003.1
Mff



mitochondrial fission factor



chr5_+_104046980 2.373 ENSMUST00000134313.1
Nudt9
nudix (nucleoside diphosphate linked moiety X)-type motif 9
chr1_+_183297060 2.372 ENSMUST00000109166.2
Aida
axin interactor, dorsalization associated

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
5.0 24.8 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
2.7 8.1 GO:0099578 regulation of translation at synapse, modulating synaptic transmission(GO:0099547) regulation of translation at postsynapse, modulating synaptic transmission(GO:0099578) positive regulation of intracellular transport of viral material(GO:1901254)
2.6 12.9 GO:1904684 negative regulation of metalloendopeptidase activity(GO:1904684)
2.4 7.1 GO:1904959 elastin biosynthetic process(GO:0051542) regulation of electron carrier activity(GO:1904732) regulation of cytochrome-c oxidase activity(GO:1904959)
2.2 6.5 GO:0034395 regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
2.0 8.1 GO:0070829 heterochromatin maintenance(GO:0070829)
1.9 5.8 GO:0046032 ADP catabolic process(GO:0046032)
1.7 8.6 GO:0042117 monocyte activation(GO:0042117)
1.7 12.0 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
1.4 4.2 GO:0002352 B cell negative selection(GO:0002352) B cell homeostatic proliferation(GO:0002358)
1.3 6.7 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
1.3 3.9 GO:2000872 positive regulation of progesterone secretion(GO:2000872)
1.3 8.8 GO:0006868 glutamine transport(GO:0006868)
1.2 3.5 GO:0002877 regulation of acute inflammatory response to non-antigenic stimulus(GO:0002877) positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
1.1 6.9 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
1.1 4.5 GO:0032053 ciliary basal body organization(GO:0032053)
1.1 11.0 GO:0051013 microtubule severing(GO:0051013)
1.1 5.4 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
1.1 12.6 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
1.0 4.1 GO:0007066 female meiosis sister chromatid cohesion(GO:0007066)
1.0 6.0 GO:0046502 uroporphyrinogen III metabolic process(GO:0046502)
1.0 3.0 GO:0090204 protein localization to nuclear pore(GO:0090204)
1.0 3.9 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
1.0 4.8 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
1.0 8.7 GO:0010587 miRNA catabolic process(GO:0010587)
1.0 2.9 GO:1905663 regulation of telomerase RNA reverse transcriptase activity(GO:1905661) positive regulation of telomerase RNA reverse transcriptase activity(GO:1905663)
0.9 2.7 GO:1903490 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.9 6.2 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.9 2.6 GO:0021570 rhombomere 4 development(GO:0021570)
0.9 4.3 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.8 3.4 GO:1905832 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778) positive regulation of spindle assembly(GO:1905832)
0.8 4.2 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.8 2.5 GO:0002277 myeloid dendritic cell activation involved in immune response(GO:0002277)
0.8 3.3 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.8 8.1 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.8 2.4 GO:0002215 defense response to nematode(GO:0002215)
0.8 6.5 GO:0071907 determination of digestive tract left/right asymmetry(GO:0071907)
0.8 2.4 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) DNA replication preinitiation complex assembly(GO:0071163) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.8 2.4 GO:2000016 negative regulation of determination of dorsal identity(GO:2000016)
0.7 2.2 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.7 8.2 GO:2000781 positive regulation of double-strand break repair(GO:2000781)
0.7 1.5 GO:0033864 positive regulation of NAD(P)H oxidase activity(GO:0033864)
0.7 2.1 GO:1903564 regulation of protein localization to cilium(GO:1903564)
0.7 3.4 GO:0051140 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.7 2.0 GO:0031660 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662)
0.7 4.7 GO:0030421 defecation(GO:0030421)
0.6 2.6 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.6 2.6 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.6 2.4 GO:0002188 translation reinitiation(GO:0002188)
0.6 6.0 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.6 5.2 GO:1900244 positive regulation of synaptic vesicle endocytosis(GO:1900244)
0.6 5.2 GO:1903207 neuron death in response to hydrogen peroxide(GO:0036476) regulation of hydrogen peroxide-induced neuron death(GO:1903207) negative regulation of hydrogen peroxide-induced neuron death(GO:1903208)
0.6 1.7 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.6 1.1 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.5 2.7 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.5 1.6 GO:0046436 D-serine catabolic process(GO:0036088) D-alanine family amino acid metabolic process(GO:0046144) D-alanine metabolic process(GO:0046436) D-alanine catabolic process(GO:0055130)
0.5 5.8 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.5 2.6 GO:0034163 regulation of toll-like receptor 9 signaling pathway(GO:0034163)
0.5 0.5 GO:1903056 regulation of melanosome organization(GO:1903056)
0.5 8.6 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.5 1.5 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.5 4.4 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.5 1.4 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.5 1.4 GO:0070429 regulation of granuloma formation(GO:0002631) negative regulation of granuloma formation(GO:0002632) regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433) tolerance induction to lipopolysaccharide(GO:0072573) negative regulation of CD40 signaling pathway(GO:2000349)
0.5 2.8 GO:0051790 acetate metabolic process(GO:0006083) short-chain fatty acid biosynthetic process(GO:0051790)
0.5 10.8 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211)
0.5 5.6 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.5 1.8 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.5 3.2 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.4 0.9 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.4 1.8 GO:0046351 disaccharide biosynthetic process(GO:0046351)
0.4 1.8 GO:0000019 regulation of mitotic recombination(GO:0000019)
0.4 2.2 GO:0010920 negative regulation of inositol phosphate biosynthetic process(GO:0010920) regulation of large conductance calcium-activated potassium channel activity(GO:1902606) positive regulation of large conductance calcium-activated potassium channel activity(GO:1902608)
0.4 1.3 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.4 3.4 GO:0002424 T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840)
0.4 0.8 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.4 3.3 GO:1904591 positive regulation of protein import(GO:1904591)
0.4 1.2 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.4 2.8 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.4 4.8 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.4 3.2 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) negative regulation of serotonin uptake(GO:0051612)
0.4 2.0 GO:1905332 positive regulation of mesonephros development(GO:0061213) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190) positive regulation of morphogenesis of an epithelium(GO:1905332)
0.4 1.6 GO:0097167 circadian regulation of translation(GO:0097167)
0.4 3.1 GO:0016139 glycoside catabolic process(GO:0016139)
0.4 4.6 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.4 13.1 GO:0002052 positive regulation of neuroblast proliferation(GO:0002052)
0.4 1.1 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.4 5.6 GO:0000076 DNA replication checkpoint(GO:0000076)
0.4 3.0 GO:0006265 DNA topological change(GO:0006265)
0.4 0.4 GO:1902263 apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
0.4 1.8 GO:0045113 regulation of integrin biosynthetic process(GO:0045113)
0.4 0.7 GO:1904688 regulation of cytoplasmic translational initiation(GO:1904688)
0.4 2.2 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.4 2.2 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.3 0.7 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.3 2.8 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.3 1.4 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.3 2.7 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.3 1.0 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.3 2.0 GO:0048254 snoRNA localization(GO:0048254)
0.3 0.6 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
0.3 1.0 GO:0006285 base-excision repair, AP site formation(GO:0006285)
0.3 1.9 GO:0015074 DNA integration(GO:0015074)
0.3 0.6 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.3 6.9 GO:0032460 negative regulation of protein oligomerization(GO:0032460)
0.3 0.9 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.3 1.2 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.3 3.6 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.3 4.5 GO:0034453 microtubule anchoring(GO:0034453)
0.3 2.6 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.3 4.3 GO:0070307 lens fiber cell development(GO:0070307)
0.3 0.6 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.3 3.4 GO:0000212 meiotic spindle organization(GO:0000212)
0.3 0.8 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.3 13.4 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.3 0.8 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.3 0.6 GO:0032055 negative regulation of translation in response to stress(GO:0032055)
0.3 1.4 GO:2000680 regulation of rubidium ion transport(GO:2000680)
0.3 6.3 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.3 0.8 GO:0036018 response to erythropoietin(GO:0036017) cellular response to erythropoietin(GO:0036018) erythropoietin-mediated signaling pathway(GO:0038162)
0.3 4.8 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.3 8.8 GO:0034724 DNA replication-independent nucleosome organization(GO:0034724)
0.3 4.8 GO:0015816 glycine transport(GO:0015816)
0.3 0.3 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.3 0.5 GO:0006680 glucosylceramide catabolic process(GO:0006680)
0.3 4.9 GO:0001675 acrosome assembly(GO:0001675)
0.3 5.2 GO:0002115 store-operated calcium entry(GO:0002115)
0.3 1.5 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.3 1.8 GO:0098535 de novo centriole assembly(GO:0097742) de novo centriole assembly involved in multi-ciliated epithelial cell differentiation(GO:0098535)
0.3 2.0 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.3 0.8 GO:0098971 anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.2 1.0 GO:0006041 glucosamine metabolic process(GO:0006041)
0.2 1.0 GO:0006014 D-ribose metabolic process(GO:0006014)
0.2 1.5 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.2 4.6 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.2 1.7 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.2 3.1 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.2 2.1 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.2 2.1 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.2 2.3 GO:0090527 actin filament reorganization(GO:0090527)
0.2 0.7 GO:1902567 immune complex clearance by monocytes and macrophages(GO:0002436) astrocyte chemotaxis(GO:0035700) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) positive regulation of immune complex clearance by monocytes and macrophages(GO:0090265) negative regulation of eosinophil activation(GO:1902567) positive regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000451) regulation of astrocyte chemotaxis(GO:2000458)
0.2 1.4 GO:0045213 neurotransmitter receptor metabolic process(GO:0045213)
0.2 0.9 GO:0032241 positive regulation of nucleobase-containing compound transport(GO:0032241)
0.2 0.5 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.2 5.9 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.2 10.1 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.2 2.5 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.2 3.3 GO:0042118 endothelial cell activation(GO:0042118)
0.2 0.4 GO:0048022 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.2 1.5 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.2 1.5 GO:0060693 regulation of branching involved in salivary gland morphogenesis(GO:0060693)
0.2 2.8 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.2 0.4 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.2 0.6 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.2 0.2 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.2 0.6 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.2 1.0 GO:0015870 acetylcholine transport(GO:0015870)
0.2 0.6 GO:1905937 male germ cell proliferation(GO:0002176) germ cell proliferation(GO:0036093) regulation of germ cell proliferation(GO:1905936) negative regulation of germ cell proliferation(GO:1905937) regulation of male germ cell proliferation(GO:2000254) negative regulation of male germ cell proliferation(GO:2000255)
0.2 1.4 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.2 3.7 GO:0043968 histone H2A acetylation(GO:0043968)
0.2 1.0 GO:0046349 amino sugar biosynthetic process(GO:0046349)
0.2 1.1 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.2 2.1 GO:0033572 transferrin transport(GO:0033572)
0.2 1.5 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.2 0.2 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.2 2.1 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.2 6.2 GO:0048266 behavioral response to pain(GO:0048266)
0.2 2.0 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.2 1.1 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.2 1.4 GO:0032229 negative regulation of synaptic transmission, GABAergic(GO:0032229)
0.2 0.2 GO:0032079 positive regulation of endodeoxyribonuclease activity(GO:0032079)
0.2 0.7 GO:0003349 epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
0.2 3.9 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.2 0.5 GO:1900157 regulation of bone mineralization involved in bone maturation(GO:1900157)
0.2 0.7 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.2 1.4 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.2 0.8 GO:0044351 macropinocytosis(GO:0044351)
0.2 11.1 GO:0043966 histone H3 acetylation(GO:0043966)
0.2 1.6 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.2 3.7 GO:0033622 integrin activation(GO:0033622)
0.2 4.9 GO:0015804 neutral amino acid transport(GO:0015804)
0.1 0.3 GO:0071288 cellular response to mercury ion(GO:0071288)
0.1 0.4 GO:0035878 nail development(GO:0035878)
0.1 0.6 GO:1905709 negative regulation of mitochondrial membrane permeability(GO:0035795) negative regulation of membrane permeability(GO:1905709)
0.1 5.0 GO:0097503 sialylation(GO:0097503)
0.1 0.6 GO:0044565 dendritic cell proliferation(GO:0044565)
0.1 3.2 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 4.1 GO:0061157 mRNA destabilization(GO:0061157)
0.1 0.8 GO:0042256 mature ribosome assembly(GO:0042256)
0.1 0.4 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.1 0.6 GO:0021586 pons maturation(GO:0021586)
0.1 1.4 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.1 4.3 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.1 0.3 GO:0060003 copper ion export(GO:0060003)
0.1 0.3 GO:1903223 positive regulation of oxidative stress-induced neuron death(GO:1903223)
0.1 0.5 GO:0018201 peptidyl-glycine modification(GO:0018201)
0.1 3.4 GO:1902175 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902175)
0.1 0.6 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.1 1.7 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 16.8 GO:0030177 positive regulation of Wnt signaling pathway(GO:0030177)
0.1 0.7 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.1 2.1 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.1 11.8 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.1 5.8 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.1 1.1 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.1 2.2 GO:2000369 regulation of clathrin-dependent endocytosis(GO:2000369)
0.1 0.4 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.1 0.9 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.1 0.6 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.1 0.7 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
0.1 1.0 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.1 0.2 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.1 0.7 GO:0071971 extracellular exosome assembly(GO:0071971) regulation of extracellular exosome assembly(GO:1903551)
0.1 0.8 GO:0051231 mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231) mitotic spindle midzone assembly(GO:0051256)
0.1 0.3 GO:0021972 corticospinal neuron axon guidance through spinal cord(GO:0021972) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) response to heparin(GO:0071503) cellular response to heparin(GO:0071504) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
0.1 0.4 GO:0031296 B cell costimulation(GO:0031296)
0.1 0.8 GO:2000809 positive regulation of synaptic vesicle clustering(GO:2000809)
0.1 1.9 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.1 0.6 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.6 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.1 0.4 GO:0071285 cellular response to lithium ion(GO:0071285)
0.1 0.5 GO:0006177 GMP biosynthetic process(GO:0006177)
0.1 0.8 GO:0060009 Sertoli cell development(GO:0060009)
0.1 0.7 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.1 0.4 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.1 0.2 GO:0072718 response to cisplatin(GO:0072718)
0.1 0.3 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.1 0.4 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.1 0.1 GO:0072076 nephrogenic mesenchyme development(GO:0072076)
0.1 1.0 GO:0038092 nodal signaling pathway(GO:0038092)
0.1 0.3 GO:0030576 Cajal body organization(GO:0030576)
0.1 1.9 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.1 1.4 GO:1902358 oxalate transport(GO:0019532) sulfate transmembrane transport(GO:1902358)
0.1 0.7 GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.1 1.7 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.1 0.3 GO:0018343 protein farnesylation(GO:0018343)
0.1 0.2 GO:1901250 regulation of lung goblet cell differentiation(GO:1901249) negative regulation of lung goblet cell differentiation(GO:1901250)
0.1 5.1 GO:0071479 cellular response to ionizing radiation(GO:0071479)
0.1 0.8 GO:0051865 protein autoubiquitination(GO:0051865)
0.1 1.0 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.1 3.9 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 2.0 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.4 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.1 0.2 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.1 5.9 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.1 0.2 GO:1904578 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
0.1 0.4 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.1 2.6 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 0.5 GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.1 1.7 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.1 1.4 GO:0033120 positive regulation of RNA splicing(GO:0033120)
0.1 0.5 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.1 1.6 GO:0006298 mismatch repair(GO:0006298)
0.1 2.2 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.1 0.2 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.1 0.8 GO:0042790 transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:0042790)
0.1 0.5 GO:0032682 negative regulation of chemokine production(GO:0032682)
0.1 0.3 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 0.5 GO:0086028 bundle of His cell to Purkinje myocyte signaling(GO:0086028) bundle of His cell action potential(GO:0086043)
0.1 1.2 GO:0001841 neural tube formation(GO:0001841)
0.1 2.1 GO:0048255 mRNA stabilization(GO:0048255)
0.1 3.0 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.1 0.7 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287) positive regulation of spindle checkpoint(GO:0090232) positive regulation of cell cycle checkpoint(GO:1901978)
0.1 1.1 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.1 0.3 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.1 0.2 GO:0060697 positive regulation of phospholipid catabolic process(GO:0060697)
0.1 0.1 GO:0036289 peptidyl-serine autophosphorylation(GO:0036289)
0.1 0.9 GO:0043084 penile erection(GO:0043084)
0.1 0.6 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 0.2 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.1 1.2 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.1 0.8 GO:0006020 inositol metabolic process(GO:0006020)
0.1 2.0 GO:0030225 macrophage differentiation(GO:0030225)
0.1 1.6 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.1 0.4 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 0.2 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.1 3.8 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.1 0.5 GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000466)
0.1 0.4 GO:0014842 skeletal muscle satellite cell proliferation(GO:0014841) regulation of skeletal muscle satellite cell proliferation(GO:0014842) skeletal muscle cell proliferation(GO:0014856) regulation of skeletal muscle cell proliferation(GO:0014857)
0.1 0.4 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.1 1.0 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.1 1.2 GO:0016180 snRNA processing(GO:0016180)
0.1 2.7 GO:0060325 face morphogenesis(GO:0060325)
0.1 0.6 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1 0.3 GO:0072015 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.1 0.8 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1 3.1 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.1 0.4 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291)
0.1 0.4 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.1 0.6 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.1 0.2 GO:0086053 AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.1 3.6 GO:0015909 long-chain fatty acid transport(GO:0015909)
0.1 1.5 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.1 0.5 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 0.1 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.1 0.2 GO:0061090 positive regulation of sequestering of zinc ion(GO:0061090)
0.1 0.3 GO:0038030 non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.1 0.4 GO:0009303 rRNA transcription(GO:0009303)
0.1 0.2 GO:0048496 maintenance of animal organ identity(GO:0048496)
0.1 0.1 GO:0043686 co-translational protein modification(GO:0043686)
0.0 0.1 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.2 GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418)
0.0 0.3 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.0 0.7 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.0 0.4 GO:0036506 maintenance of unfolded protein(GO:0036506) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.0 0.1 GO:0070141 response to UV-A(GO:0070141) cellular response to UV-A(GO:0071492)
0.0 0.3 GO:0099004 calmodulin dependent kinase signaling pathway(GO:0099004)
0.0 0.1 GO:0010840 regulation of circadian sleep/wake cycle, wakefulness(GO:0010840) positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841) circadian sleep/wake cycle, wakefulness(GO:0042746) positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.0 4.6 GO:0030168 platelet activation(GO:0030168)
0.0 0.7 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.9 GO:0045730 respiratory burst(GO:0045730)
0.0 3.0 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.4 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.5 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.0 0.3 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.4 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.1 GO:0090315 negative regulation of protein targeting to membrane(GO:0090315)
0.0 0.1 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.6 GO:0031050 dsRNA fragmentation(GO:0031050) production of miRNAs involved in gene silencing by miRNA(GO:0035196) production of small RNA involved in gene silencing by RNA(GO:0070918)
0.0 0.3 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.1 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
0.0 0.4 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 0.6 GO:0050691 regulation of defense response to virus by host(GO:0050691)
0.0 0.6 GO:0051601 exocyst localization(GO:0051601)
0.0 1.8 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 0.7 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.8 GO:0007224 smoothened signaling pathway(GO:0007224)
0.0 0.2 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.3 GO:0006183 GTP biosynthetic process(GO:0006183)
0.0 2.7 GO:0043473 pigmentation(GO:0043473)
0.0 0.2 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 1.3 GO:0006024 glycosaminoglycan biosynthetic process(GO:0006024)
0.0 0.2 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.2 GO:0051220 cytoplasmic sequestering of protein(GO:0051220)
0.0 0.6 GO:0035115 embryonic forelimb morphogenesis(GO:0035115)
0.0 1.3 GO:2000736 regulation of stem cell differentiation(GO:2000736)
0.0 0.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 1.1 GO:0007097 nuclear migration(GO:0007097)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.4 GO:0045161 neuronal ion channel clustering(GO:0045161)
0.0 0.2 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.0 0.1 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.2 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.4 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.9 GO:0006270 DNA replication initiation(GO:0006270)
0.0 1.3 GO:0060021 palate development(GO:0060021)
0.0 0.3 GO:0071868 cellular response to monoamine stimulus(GO:0071868) cellular response to catecholamine stimulus(GO:0071870)
0.0 0.1 GO:1902952 positive regulation of dendritic spine maintenance(GO:1902952)
0.0 0.1 GO:0002759 regulation of antimicrobial humoral response(GO:0002759)
0.0 0.2 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.0 1.4 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.0 2.4 GO:0001889 liver development(GO:0001889)
0.0 0.1 GO:0009405 pathogenesis(GO:0009405)
0.0 0.1 GO:0040016 embryonic cleavage(GO:0040016)
0.0 4.8 GO:1903507 negative regulation of RNA biosynthetic process(GO:1902679) negative regulation of nucleic acid-templated transcription(GO:1903507)
0.0 1.0 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.3 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 0.6 GO:0040019 positive regulation of embryonic development(GO:0040019)
0.0 2.2 GO:0030010 establishment of cell polarity(GO:0030010)
0.0 0.2 GO:0032310 prostaglandin secretion(GO:0032310)
0.0 0.2 GO:1903691 regulation of wound healing, spreading of epidermal cells(GO:1903689) positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.5 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 0.6 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.1 GO:0009048 dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.5 GO:0000154 rRNA modification(GO:0000154)
0.0 0.6 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.4 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.0 0.1 GO:0015786 UDP-glucose transport(GO:0015786)
0.0 0.4 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.0 0.6 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.0 0.3 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 0.7 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 1.1 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.2 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.0 0.1 GO:0072395 signal transduction involved in cell cycle checkpoint(GO:0072395) signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in DNA damage checkpoint(GO:0072422)
0.0 1.1 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)
0.0 0.5 GO:0021591 ventricular system development(GO:0021591)
0.0 0.2 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 2.7 GO:0016358 dendrite development(GO:0016358)
0.0 0.8 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 1.1 GO:0006334 nucleosome assembly(GO:0006334)
0.0 6.4 GO:0007409 axonogenesis(GO:0007409)
0.0 0.3 GO:0046325 negative regulation of glucose import(GO:0046325)
0.0 1.4 GO:0030509 BMP signaling pathway(GO:0030509)
0.0 0.7 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.5 GO:0019236 response to pheromone(GO:0019236)
0.0 0.3 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.1 GO:0010259 multicellular organism aging(GO:0010259)
0.0 0.1 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.2 GO:0046685 response to arsenic-containing substance(GO:0046685)
0.0 1.0 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.3 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.8 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.6 GO:2001237 negative regulation of extrinsic apoptotic signaling pathway(GO:2001237)
0.0 0.2 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.7 GO:0030042 actin filament depolymerization(GO:0030042)
0.0 0.1 GO:0019509 L-methionine salvage from methylthioadenosine(GO:0019509)
0.0 0.2 GO:0031111 negative regulation of microtubule polymerization or depolymerization(GO:0031111)
0.0 0.1 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.0 0.2 GO:1990845 adaptive thermogenesis(GO:1990845)
0.0 1.1 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.0 0.1 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.0 0.1 GO:0033280 response to vitamin D(GO:0033280)
0.0 0.1 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.0 0.1 GO:1905516 positive regulation of fertilization(GO:1905516) positive regulation of acrosome reaction(GO:2000344)
0.0 0.4 GO:0030593 neutrophil chemotaxis(GO:0030593)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 16.6 GO:0044611 nuclear pore inner ring(GO:0044611)
2.7 8.2 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
2.3 6.8 GO:0033186 CAF-1 complex(GO:0033186)
2.0 8.1 GO:1902737 dendritic filopodium(GO:1902737)
1.8 8.8 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
1.4 4.2 GO:0035101 FACT complex(GO:0035101)
1.1 5.4 GO:1990037 Lewy body core(GO:1990037)
1.1 5.4 GO:0048476 Holliday junction resolvase complex(GO:0048476)
1.1 6.3 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
1.0 8.3 GO:0005826 actomyosin contractile ring(GO:0005826)
1.0 10.1 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
1.0 3.8 GO:0031084 BLOC-2 complex(GO:0031084)
1.0 4.8 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.9 6.6 GO:0001740 Barr body(GO:0001740)
0.9 14.9 GO:0005641 nuclear envelope lumen(GO:0005641)
0.9 2.6 GO:0030905 retromer, tubulation complex(GO:0030905)
0.8 8.6 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.7 9.0 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.7 4.8 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.7 5.3 GO:0005664 nuclear origin of replication recognition complex(GO:0005664)
0.6 4.5 GO:0030896 checkpoint clamp complex(GO:0030896)
0.6 4.2 GO:0031298 replication fork protection complex(GO:0031298)
0.6 6.0 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.5 1.9 GO:0030870 Mre11 complex(GO:0030870)
0.5 1.4 GO:1990047 spindle matrix(GO:1990047)
0.5 1.4 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.5 1.9 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.4 4.6 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.4 8.7 GO:0030914 STAGA complex(GO:0030914)
0.4 3.3 GO:0042382 paraspeckles(GO:0042382)
0.4 4.1 GO:0071141 SMAD protein complex(GO:0071141)
0.4 2.9 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.4 9.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.4 2.3 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.4 2.6 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.4 2.6 GO:0099061 integral component of postsynaptic density membrane(GO:0099061) intrinsic component of postsynaptic density membrane(GO:0099146)
0.4 2.6 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.4 3.7 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.4 6.9 GO:0097431 mitotic spindle pole(GO:0097431)
0.3 1.0 GO:0070985 TFIIK complex(GO:0070985)
0.3 1.0 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.3 3.0 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.3 2.2 GO:0005638 lamin filament(GO:0005638)
0.3 14.6 GO:0031519 PcG protein complex(GO:0031519)
0.3 1.8 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.3 7.5 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.3 2.5 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.3 1.8 GO:0033503 HULC complex(GO:0033503)
0.3 2.8 GO:0000243 commitment complex(GO:0000243)
0.2 1.4 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.2 4.5 GO:0035253 ciliary rootlet(GO:0035253)
0.2 2.4 GO:0043020 NADPH oxidase complex(GO:0043020)
0.2 9.1 GO:0016592 mediator complex(GO:0016592) core mediator complex(GO:0070847)
0.2 0.8 GO:0032127 dense core granule membrane(GO:0032127)
0.2 1.1 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.2 6.7 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.2 2.6 GO:1990635 proximal dendrite(GO:1990635)
0.2 1.4 GO:0044666 MLL3/4 complex(GO:0044666)
0.2 2.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.2 1.2 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.2 0.6 GO:0098842 postsynaptic early endosome(GO:0098842)
0.2 3.4 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.2 0.6 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.2 1.5 GO:0031415 NatA complex(GO:0031415)
0.2 1.1 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.2 0.7 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.2 2.7 GO:0001673 male germ cell nucleus(GO:0001673)
0.2 0.5 GO:0034457 Mpp10 complex(GO:0034457)
0.2 0.7 GO:0008537 proteasome activator complex(GO:0008537)
0.2 2.8 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.2 1.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.2 2.2 GO:0042405 nuclear inclusion body(GO:0042405)
0.2 1.7 GO:0034464 BBSome(GO:0034464)
0.2 0.9 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 1.3 GO:0019908 nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.1 0.9 GO:0097443 sorting endosome(GO:0097443)
0.1 0.6 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.1 0.6 GO:0097450 astrocyte end-foot(GO:0097450)
0.1 4.4 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1 1.1 GO:0097427 microtubule bundle(GO:0097427)
0.1 2.5 GO:0000242 pericentriolar material(GO:0000242)
0.1 3.2 GO:0031091 platelet alpha granule(GO:0031091)
0.1 7.7 GO:0016235 aggresome(GO:0016235)
0.1 1.6 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 10.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 0.8 GO:1990075 periciliary membrane compartment(GO:1990075)
0.1 1.4 GO:0043083 synaptic cleft(GO:0043083)
0.1 8.1 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 7.9 GO:0005643 nuclear pore(GO:0005643)
0.1 0.7 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 31.7 GO:0031965 nuclear membrane(GO:0031965)
0.1 4.3 GO:0015030 Cajal body(GO:0015030)
0.1 1.5 GO:0005869 dynactin complex(GO:0005869)
0.1 1.3 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 0.3 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.1 0.6 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.1 2.1 GO:0031528 microvillus membrane(GO:0031528)
0.1 12.8 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 1.5 GO:0043203 axon hillock(GO:0043203)
0.1 7.0 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 0.9 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 0.2 GO:0031088 platelet dense granule membrane(GO:0031088)
0.1 2.8 GO:0099634 postsynaptic specialization membrane(GO:0099634)
0.1 1.0 GO:0032806 carboxy-terminal domain protein kinase complex(GO:0032806)
0.1 7.0 GO:0042629 mast cell granule(GO:0042629)
0.1 0.3 GO:0099524 region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524)
0.1 0.7 GO:0071203 WASH complex(GO:0071203)
0.1 0.6 GO:0071547 piP-body(GO:0071547)
0.1 0.3 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 1.0 GO:0090543 Flemming body(GO:0090543)
0.1 1.7 GO:0005797 Golgi medial cisterna(GO:0005797)
0.1 1.4 GO:0032039 integrator complex(GO:0032039)
0.1 0.8 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 1.7 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.1 0.9 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 9.4 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.1 1.3 GO:0010369 chromocenter(GO:0010369)
0.1 12.2 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1 0.4 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 1.1 GO:0071011 precatalytic spliceosome(GO:0071011)
0.1 0.8 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 0.2 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.1 2.3 GO:0016460 myosin II complex(GO:0016460)
0.1 0.7 GO:1990752 microtubule plus-end(GO:0035371) microtubule end(GO:1990752)
0.1 0.2 GO:0005687 U4 snRNP(GO:0005687)
0.1 0.7 GO:0031514 motile cilium(GO:0031514)
0.1 0.6 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.1 0.4 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009) pigment granule membrane(GO:0090741)
0.1 1.1 GO:0035097 histone methyltransferase complex(GO:0035097)
0.1 1.2 GO:0032040 small-subunit processome(GO:0032040)
0.1 1.6 GO:0033202 DNA helicase complex(GO:0033202)
0.1 1.2 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 1.1 GO:0001741 XY body(GO:0001741) inactive sex chromosome(GO:0098577) condensed chromatin of inactivated sex chromosome(GO:0098578)
0.1 3.0 GO:0045171 intercellular bridge(GO:0045171)
0.1 2.9 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 24.0 GO:0005667 transcription factor complex(GO:0005667)
0.1 0.4 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1 1.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 0.6 GO:0033391 chromatoid body(GO:0033391)
0.1 1.1 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 3.6 GO:0016605 PML body(GO:0016605)
0.1 0.6 GO:0031045 dense core granule(GO:0031045)
0.0 0.5 GO:0070545 PeBoW complex(GO:0070545)
0.0 7.7 GO:0005681 spliceosomal complex(GO:0005681)
0.0 0.4 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.4 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 4.5 GO:0005882 intermediate filament(GO:0005882)
0.0 3.1 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 3.1 GO:0016528 sarcoplasm(GO:0016528)
0.0 0.1 GO:0001651 dense fibrillar component(GO:0001651)
0.0 0.7 GO:0005876 spindle microtubule(GO:0005876)
0.0 1.5 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 2.2 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.1 GO:0106003 amyloid-beta complex(GO:0106003)
0.0 0.6 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 6.0 GO:0030427 site of polarized growth(GO:0030427)
0.0 1.4 GO:0098797 plasma membrane protein complex(GO:0098797)
0.0 0.4 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.4 GO:0036501 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) UFD1-NPL4 complex(GO:0036501)
0.0 2.0 GO:0097540 axonemal microtubule(GO:0005879) sperm flagellum(GO:0036126) axonemal central pair(GO:0097540) axonemal outer doublet(GO:0097545) A axonemal microtubule(GO:0097649) B axonemal microtubule(GO:0097650) 9+2 motile cilium(GO:0097729) C1 axonemal microtubule(GO:1990719) C2 axonemal microtubule(GO:1990720)
0.0 0.8 GO:0090544 BAF-type complex(GO:0090544)
0.0 0.1 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.4 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 9.5 GO:0005813 centrosome(GO:0005813)
0.0 0.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 3.5 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.7 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.2 GO:0030686 90S preribosome(GO:0030686)
0.0 0.1 GO:0000346 transcription export complex(GO:0000346)
0.0 0.9 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.7 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.2 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.0 1.5 GO:0034399 nuclear periphery(GO:0034399)
0.0 0.9 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 1.0 GO:0043034 costamere(GO:0043034)
0.0 8.0 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.3 GO:0005839 proteasome core complex(GO:0005839)
0.0 7.4 GO:0030529 intracellular ribonucleoprotein complex(GO:0030529)
0.0 0.2 GO:0042587 glycogen granule(GO:0042587)
0.0 0.8 GO:0016459 myosin complex(GO:0016459)
0.0 0.2 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.2 GO:0032009 early phagosome(GO:0032009)
0.0 0.2 GO:0097512 cardiac myofibril(GO:0097512)
0.0 1.7 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.3 GO:0000145 exocyst(GO:0000145)
0.0 1.5 GO:0005902 microvillus(GO:0005902)
0.0 3.7 GO:0016607 nuclear speck(GO:0016607)
0.0 2.3 GO:0005938 cell cortex(GO:0005938)
0.0 0.1 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.5 GO:0014704 intercalated disc(GO:0014704)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.0 GO:0044308 axonal spine(GO:0044308)
0.0 0.5 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 0.2 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 2.6 GO:0099572 postsynaptic specialization(GO:0099572)
0.0 0.6 GO:0034707 chloride channel complex(GO:0034707)
0.0 2.5 GO:0005874 microtubule(GO:0005874)
0.0 0.4 GO:0000800 lateral element(GO:0000800)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 8.1 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
2.2 12.9 GO:1902944 aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902944)
1.8 7.4 GO:0043682 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
1.8 8.8 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
1.6 6.5 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
1.5 4.5 GO:0035500 MH2 domain binding(GO:0035500)
1.5 7.4 GO:0017108 5'-flap endonuclease activity(GO:0017108)
1.3 8.9 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
1.2 6.2 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
1.2 8.7 GO:0033592 RNA strand annealing activity(GO:0033592)
1.2 3.6 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
1.2 4.8 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
1.0 4.2 GO:0008859 exoribonuclease II activity(GO:0008859)
1.0 4.9 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.9 2.8 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.9 5.4 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.9 6.9 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.9 6.0 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.8 5.6 GO:0070087 chromo shadow domain binding(GO:0070087)
0.8 3.1 GO:0004945 angiotensin type II receptor activity(GO:0004945)
0.7 5.8 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.7 5.8 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.7 2.9 GO:0035851 histone deacetylase activity (H4-K16 specific)(GO:0034739) Krueppel-associated box domain binding(GO:0035851)
0.7 2.2 GO:0036033 mediator complex binding(GO:0036033)
0.7 8.6 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.7 2.9 GO:0003721 telomerase RNA reverse transcriptase activity(GO:0003721)
0.7 6.1 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.7 32.0 GO:0050699 WW domain binding(GO:0050699)
0.7 4.6 GO:0042289 MHC class II protein binding(GO:0042289)
0.6 2.6 GO:1990460 leptin receptor binding(GO:1990460)
0.6 16.6 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.6 1.8 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.6 3.0 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.6 1.8 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.6 3.5 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.6 3.9 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.5 2.2 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.5 3.7 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.5 7.5 GO:0003688 DNA replication origin binding(GO:0003688)
0.5 1.4 GO:0046969 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.5 2.3 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.4 1.3 GO:0015928 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.4 4.2 GO:0051434 BH3 domain binding(GO:0051434)
0.4 1.7 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.4 10.1 GO:0003746 translation elongation factor activity(GO:0003746)
0.4 3.7 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.4 0.8 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.4 1.6 GO:0003884 D-amino-acid oxidase activity(GO:0003884)
0.4 5.4 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.3 4.8 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.3 1.4 GO:0004104 cholinesterase activity(GO:0004104)
0.3 1.3 GO:0004844 mismatch base pair DNA N-glycosylase activity(GO:0000700) uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.3 2.2 GO:0004586 ornithine decarboxylase activity(GO:0004586)
0.3 7.0 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.3 11.9 GO:0042162 telomeric DNA binding(GO:0042162)
0.3 1.5 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
0.3 0.9 GO:0004998 transferrin receptor activity(GO:0004998)
0.3 0.9 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.3 2.6 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.3 2.0 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.3 1.7 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.3 2.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.3 2.4 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.3 1.3 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.3 3.3 GO:1990405 protein antigen binding(GO:1990405)
0.3 0.8 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.2 0.7 GO:0003692 left-handed Z-DNA binding(GO:0003692)
0.2 1.2 GO:0038100 nodal binding(GO:0038100)
0.2 1.6 GO:0016936 galactoside binding(GO:0016936)
0.2 0.7 GO:0035717 chemokine (C-C motif) ligand 7 binding(GO:0035717)
0.2 6.4 GO:0070840 dynein complex binding(GO:0070840)
0.2 1.0 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.2 7.0 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.2 1.4 GO:0140034 methylated histone binding(GO:0035064) methylation-dependent protein binding(GO:0140034)
0.2 0.8 GO:0061665 SUMO ligase activity(GO:0061665)
0.2 1.0 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.2 9.7 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.2 16.4 GO:0003725 double-stranded RNA binding(GO:0003725)
0.2 4.4 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.2 1.5 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.2 1.3 GO:0097322 7SK snRNA binding(GO:0097322)
0.2 8.4 GO:0008536 Ran GTPase binding(GO:0008536)
0.2 1.5 GO:0045545 syndecan binding(GO:0045545)
0.2 1.6 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.2 1.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.2 2.8 GO:0043495 protein membrane anchor(GO:0043495)
0.2 0.2 GO:0097100 supercoiled DNA binding(GO:0097100)
0.2 1.6 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.2 4.1 GO:0008187 poly-pyrimidine tract binding(GO:0008187)
0.2 2.7 GO:0010181 FMN binding(GO:0010181)
0.2 1.7 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.2 1.0 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.2 7.2 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.2 1.3 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.2 1.3 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.2 2.1 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.2 10.6 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.2 1.1 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.2 0.5 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.2 1.9 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.2 4.9 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.2 4.9 GO:0031491 nucleosome binding(GO:0031491)
0.2 0.6 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.2 5.2 GO:0008198 ferrous iron binding(GO:0008198)
0.2 0.6 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.2 2.7 GO:0045504 dynein heavy chain binding(GO:0045504)
0.2 0.5 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1 10.3 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 0.6 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.1 3.4 GO:0070064 proline-rich region binding(GO:0070064)
0.1 1.5 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.1 0.8 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 2.5 GO:0042608 T cell receptor binding(GO:0042608)
0.1 1.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 1.6 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 2.1 GO:0031432 titin binding(GO:0031432)
0.1 6.4 GO:0042169 SH2 domain binding(GO:0042169)
0.1 0.3 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.1 0.5 GO:0070976 TIR domain binding(GO:0070976)
0.1 4.5 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.1 2.0 GO:0008432 JUN kinase binding(GO:0008432)
0.1 2.2 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 1.5 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 6.6 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.1 1.0 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 1.4 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.1 0.5 GO:0004127 cytidylate kinase activity(GO:0004127)
0.1 6.2 GO:0005109 frizzled binding(GO:0005109)
0.1 15.7 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 2.5 GO:0005521 lamin binding(GO:0005521)
0.1 0.5 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 0.8 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.1 2.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 0.3 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.1 6.0 GO:0003727 single-stranded RNA binding(GO:0003727)
0.1 0.3 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.1 0.6 GO:0035827 rubidium ion transmembrane transporter activity(GO:0035827)
0.1 3.3 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 2.6 GO:0008373 sialyltransferase activity(GO:0008373)
0.1 3.2 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1 0.3 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 1.5 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.1 0.6 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 2.0 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 1.5 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.1 1.2 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.1 0.4 GO:0004092 carnitine O-acetyltransferase activity(GO:0004092)
0.1 3.9 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 0.6 GO:0031013 troponin I binding(GO:0031013)
0.1 1.7 GO:0005536 glucose binding(GO:0005536)
0.1 0.3 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.1 1.3 GO:0015215 nucleotide transmembrane transporter activity(GO:0015215)
0.1 0.5 GO:0035240 dopamine binding(GO:0035240)
0.1 0.5 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 0.4 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.1 1.4 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 4.2 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 1.8 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.1 0.7 GO:1901612 phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
0.1 26.3 GO:0005096 GTPase activator activity(GO:0005096)
0.1 1.3 GO:0035613 RNA stem-loop binding(GO:0035613)
0.1 3.6 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 4.7 GO:0008026 ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.1 0.2 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.1 2.6 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 0.5 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 1.1 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.1 0.4 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 0.4 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 0.8 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 0.6 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 0.2 GO:0022850 serotonin-gated cation-selective channel activity(GO:0022850)
0.1 2.3 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 3.4 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 0.7 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.6 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 0.7 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.1 0.2 GO:0030519 snoRNP binding(GO:0030519)
0.1 0.8 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 0.2 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 0.3 GO:0050347 trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347)
0.1 0.6 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.1 1.6 GO:0051018 protein kinase A binding(GO:0051018)
0.1 0.4 GO:0017040 ceramidase activity(GO:0017040)
0.1 2.9 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 2.7 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.1 0.6 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021)
0.1 0.4 GO:0019238 cyclohydrolase activity(GO:0019238)
0.1 1.1 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 0.4 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.1 5.4 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1 0.4 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.3 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.4 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.9 GO:0031005 filamin binding(GO:0031005)
0.0 0.2 GO:1990932 5.8S rRNA binding(GO:1990932)
0.0 0.0 GO:1902121 lithocholic acid binding(GO:1902121)
0.0 0.9 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 1.3 GO:0035254 glutamate receptor binding(GO:0035254)
0.0 0.1 GO:0019002 GMP binding(GO:0019002)
0.0 2.9 GO:0005178 integrin binding(GO:0005178)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.3 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 6.3 GO:0008201 heparin binding(GO:0008201)
0.0 0.3 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.0 0.4 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.2 GO:0099103 channel activator activity(GO:0099103) potassium channel activator activity(GO:0099104)
0.0 1.0 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.4 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 2.3 GO:0019894 kinesin binding(GO:0019894)
0.0 1.1 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.3 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0 2.4 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.2 GO:0086077 gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
0.0 0.8 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.2 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.2 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
0.0 0.3 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.3 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 1.2 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 11.3 GO:0045296 cadherin binding(GO:0045296)
0.0 3.6 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 1.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 1.6 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.2 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 1.2 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 6.9 GO:0051020 GTPase binding(GO:0051020)
0.0 5.4 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.7 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 4.3 GO:0008301 DNA binding, bending(GO:0008301)
0.0 2.0 GO:0017022 myosin binding(GO:0017022)
0.0 0.1 GO:0004782 sulfinoalanine decarboxylase activity(GO:0004782)
0.0 1.8 GO:0003720 telomerase activity(GO:0003720)
0.0 1.0 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.4 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.1 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.1 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.7 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.2 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.0 11.4 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.1 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.0 0.1 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.1 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.3 GO:0070888 E-box binding(GO:0070888)
0.0 0.5 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 0.2 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.4 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.1 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.2 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.5 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.2 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.4 GO:0015036 disulfide oxidoreductase activity(GO:0015036)
0.0 0.4 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.1 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.3 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.0 GO:0004637 phosphoribosylamine-glycine ligase activity(GO:0004637)
0.0 0.1 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 2.1 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 0.5 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.0 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.1 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.2 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.1 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.0 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.0 0.1 GO:0001601 peptide YY receptor activity(GO:0001601)
0.0 0.2 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 5.5 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.0 0.0 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.8 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.2 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 1.2 GO:0017124 SH3 domain binding(GO:0017124)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 35.4 PID_P75_NTR_PATHWAY p75(NTR)-mediated signaling
0.3 4.2 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.3 11.5 PID_ATM_PATHWAY ATM pathway
0.2 6.6 PID_WNT_CANONICAL_PATHWAY Canonical Wnt signaling pathway
0.2 8.1 PID_ATR_PATHWAY ATR signaling pathway
0.2 4.7 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.2 8.4 PID_PS1_PATHWAY Presenilin action in Notch and Wnt signaling
0.2 1.4 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.2 0.8 PID_RETINOIC_ACID_PATHWAY Retinoic acid receptors-mediated signaling
0.2 0.7 PID_ERBB4_PATHWAY ErbB4 signaling events
0.2 7.9 PID_AURORA_B_PATHWAY Aurora B signaling
0.2 6.1 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.2 7.0 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.2 7.6 ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY PI3K Pathway
0.2 0.9 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 2.3 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.1 6.4 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.1 3.7 PID_AMB2_NEUTROPHILS_PATHWAY amb2 Integrin signaling
0.1 4.3 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 2.7 PID_THROMBIN_PAR1_PATHWAY PAR1-mediated thrombin signaling events
0.1 2.9 PID_IL1_PATHWAY IL1-mediated signaling events
0.1 2.0 PID_BARD1_PATHWAY BARD1 signaling events
0.1 1.4 PID_NFKAPPAB_CANONICAL_PATHWAY Canonical NF-kappaB pathway
0.1 2.0 PID_IL2_PI3K_PATHWAY IL2 signaling events mediated by PI3K
0.1 1.3 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 3.9 PID_P38_ALPHA_BETA_PATHWAY Regulation of p38-alpha and p38-beta
0.1 3.9 PID_IL8_CXCR2_PATHWAY IL8- and CXCR2-mediated signaling events
0.1 2.0 PID_MYC_PATHWAY C-MYC pathway
0.1 2.6 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.1 1.4 PID_ATF2_PATHWAY ATF-2 transcription factor network
0.1 4.1 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 5.6 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 4.1 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.1 4.2 PID_MTOR_4PATHWAY mTOR signaling pathway
0.1 2.0 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.1 0.8 PID_SYNDECAN_2_PATHWAY Syndecan-2-mediated signaling events
0.1 1.4 ST_GA12_PATHWAY G alpha 12 Pathway
0.1 4.9 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.1 2.4 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.1 0.9 SIG_CHEMOTAXIS Genes related to chemotaxis
0.1 1.4 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 1.1 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.1 0.4 ST_PAC1_RECEPTOR_PATHWAY PAC1 Receptor Pathway
0.0 3.8 PID_CMYB_PATHWAY C-MYB transcription factor network
0.0 0.8 PID_RHOA_PATHWAY RhoA signaling pathway
0.0 0.8 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.4 PID_MET_PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 7.7 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.6 PID_MAPK_TRK_PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 1.4 PID_PLK1_PATHWAY PLK1 signaling events
0.0 1.8 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.0 0.4 PID_ER_NONGENOMIC_PATHWAY Plasma membrane estrogen receptor signaling
0.0 1.1 PID_P53_REGULATION_PATHWAY p53 pathway
0.0 0.6 ST_B_CELL_ANTIGEN_RECEPTOR B Cell Antigen Receptor
0.0 0.9 PID_RB_1PATHWAY Regulation of retinoblastoma protein
0.0 1.0 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.1 PID_NOTCH_PATHWAY Notch signaling pathway
0.0 1.3 NABA_COLLAGENS Genes encoding collagen proteins
0.0 0.3 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.0 1.0 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network
0.0 1.4 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.0 4.0 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.7 ST_FAS_SIGNALING_PATHWAY Fas Signaling Pathway
0.0 0.8 PID_KIT_PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.4 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 1.3 PID_P53_DOWNSTREAM_PATHWAY Direct p53 effectors
0.0 0.2 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.0 0.4 PID_REELIN_PATHWAY Reelin signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 9.2 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.6 8.6 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.6 19.4 REACTOME_NEP_NS2_INTERACTS_WITH_THE_CELLULAR_EXPORT_MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.5 8.4 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.5 2.8 REACTOME_ETHANOL_OXIDATION Genes involved in Ethanol oxidation
0.4 19.4 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.4 9.1 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.3 8.8 REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB Genes involved in PKA-mediated phosphorylation of CREB
0.3 8.9 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.2 5.8 REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS Genes involved in Activation of ATR in response to replication stress
0.2 33.1 REACTOME_MRNA_SPLICING Genes involved in mRNA Splicing
0.2 3.5 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.2 0.9 REACTOME_SCFSKP2_MEDIATED_DEGRADATION_OF_P27_P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.2 21.7 REACTOME_CELL_DEATH_SIGNALLING_VIA_NRAGE_NRIF_AND_NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.2 1.4 REACTOME_CYCLIN_E_ASSOCIATED_EVENTS_DURING_G1_S_TRANSITION_ Genes involved in Cyclin E associated events during G1/S transition
0.2 1.2 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.2 4.3 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.2 6.6 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.2 4.6 REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.2 21.0 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.2 1.9 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.2 11.4 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.2 3.3 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
0.2 2.0 REACTOME_MRNA_CAPPING Genes involved in mRNA Capping
0.1 7.0 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.1 2.3 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.1 14.3 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.1 2.0 REACTOME_MEIOTIC_RECOMBINATION Genes involved in Meiotic Recombination
0.1 1.3 REACTOME_ELONGATION_ARREST_AND_RECOVERY Genes involved in Elongation arrest and recovery
0.1 1.7 REACTOME_ANTIGEN_PROCESSING_CROSS_PRESENTATION Genes involved in Antigen processing-Cross presentation
0.1 4.4 REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1 8.5 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 4.3 REACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.1 3.1 REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.1 2.2 REACTOME_FANCONI_ANEMIA_PATHWAY Genes involved in Fanconi Anemia pathway
0.1 0.8 REACTOME_ACTIVATED_TAK1_MEDIATES_P38_MAPK_ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.1 0.7 REACTOME_BETA_DEFENSINS Genes involved in Beta defensins
0.1 4.0 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA Genes involved in G beta:gamma signalling through PLC beta
0.1 8.0 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 3.2 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.1 4.8 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 1.1 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 0.9 REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1 1.1 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 1.8 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 2.9 REACTOME_IL1_SIGNALING Genes involved in Interleukin-1 signaling
0.1 7.6 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 0.9 REACTOME_NOD1_2_SIGNALING_PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.1 1.3 REACTOME_RNA_POL_II_PRE_TRANSCRIPTION_EVENTS Genes involved in RNA Polymerase II Pre-transcription Events
0.1 0.9 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 0.9 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.1 1.0 REACTOME_GLUCOSE_TRANSPORT Genes involved in Glucose transport
0.1 1.9 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.1 0.7 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.0 1.0 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 1.4 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.0 3.0 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 1.0 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 10.5 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 1.2 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.3 REACTOME_P38MAPK_EVENTS Genes involved in p38MAPK events
0.0 0.6 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.6 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.6 REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.8 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 0.4 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.7 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 0.1 REACTOME_ADP_SIGNALLING_THROUGH_P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.6 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.8 REACTOME_RECYCLING_PATHWAY_OF_L1 Genes involved in Recycling pathway of L1
0.0 0.2 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.0 0.6 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
0.0 0.3 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.5 REACTOME_SPHINGOLIPID_METABOLISM Genes involved in Sphingolipid metabolism
0.0 1.5 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 1.2 REACTOME_TRANSLATION Genes involved in Translation
0.0 1.9 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.4 REACTOME_ACYL_CHAIN_REMODELLING_OF_PG Genes involved in Acyl chain remodelling of PG
0.0 1.6 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.3 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.0 1.2 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.3 REACTOME_REGULATION_OF_WATER_BALANCE_BY_RENAL_AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 1.3 REACTOME_G_ALPHA_S_SIGNALLING_EVENTS Genes involved in G alpha (s) signalling events
0.0 0.4 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.6 REACTOME_DNA_REPAIR Genes involved in DNA Repair
0.0 0.4 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)