Motif ID: Trp53

Z-value: 1.132


Transcription factors associated with Trp53:

Gene SymbolEntrez IDGene Name
Trp53 ENSMUSG00000059552.7 Trp53

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Trp53mm10_v2_chr11_+_69580359_695803820.829.3e-10Click!


Activity profile for motif Trp53.

activity profile for motif Trp53


Sorted Z-values histogram for motif Trp53

Sorted Z-values for motif Trp53



Network of associatons between targets according to the STRING database.



First level regulatory network of Trp53

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_24760311 14.422 ENSMUST00000063956.5
Cd177
CD177 antigen
chr3_+_90669063 11.437 ENSMUST00000069927.8
S100a8
S100 calcium binding protein A8 (calgranulin A)
chr16_+_36253046 9.168 ENSMUST00000063539.6
2010005H15Rik
RIKEN cDNA 2010005H15 gene
chr17_-_33890539 9.025 ENSMUST00000173386.1
Kifc1
kinesin family member C1
chr17_-_33890584 8.875 ENSMUST00000114361.2
ENSMUST00000173492.1
Kifc1

kinesin family member C1

chr17_-_35066170 7.765 ENSMUST00000174190.1
ENSMUST00000097337.1
AU023871

expressed sequence AU023871

chr10_+_75564086 6.649 ENSMUST00000141062.1
ENSMUST00000152657.1
Ggt1

gamma-glutamyltransferase 1

chr4_+_115057683 6.456 ENSMUST00000161601.1
Tal1
T cell acute lymphocytic leukemia 1
chr4_+_115057410 6.232 ENSMUST00000136946.1
Tal1
T cell acute lymphocytic leukemia 1
chr17_+_28207778 6.122 ENSMUST00000002327.5
Def6
differentially expressed in FDCP 6
chr8_+_94977101 6.043 ENSMUST00000179619.1
Gpr56
G protein-coupled receptor 56
chr6_-_116461024 5.704 ENSMUST00000164547.1
ENSMUST00000170186.1
Alox5

arachidonate 5-lipoxygenase

chr14_-_55944536 5.583 ENSMUST00000022834.6
Cma1
chymase 1, mast cell
chr4_+_155790439 5.364 ENSMUST00000165000.1
Ankrd65
ankyrin repeat domain 65
chr3_-_132950043 5.181 ENSMUST00000117164.1
ENSMUST00000093971.4
ENSMUST00000042729.9
ENSMUST00000042744.9
ENSMUST00000117811.1
Npnt




nephronectin




chr4_-_134254076 5.081 ENSMUST00000060050.5
Grrp1
glycine/arginine rich protein 1
chr8_-_22185758 4.968 ENSMUST00000046916.7
Ckap2
cytoskeleton associated protein 2
chr6_-_116461151 4.846 ENSMUST00000026795.6
Alox5
arachidonate 5-lipoxygenase
chr11_-_102925086 4.778 ENSMUST00000021311.9
Kif18b
kinesin family member 18B
chr17_+_35821675 4.660 ENSMUST00000003635.6
Ier3
immediate early response 3
chr11_+_58948890 4.607 ENSMUST00000078267.3
Hist3h2ba
histone cluster 3, H2ba
chrX_-_142306170 4.114 ENSMUST00000134825.2
Kcne1l
potassium voltage-gated channel, Isk-related family, member 1-like, pseudogene
chr9_+_72438519 4.023 ENSMUST00000184604.1
Mns1
meiosis-specific nuclear structural protein 1
chr15_+_85859689 3.899 ENSMUST00000170629.1
Gtse1
G two S phase expressed protein 1
chr6_-_128891105 3.890 ENSMUST00000178918.1
ENSMUST00000160290.1
BC035044

cDNA sequence BC035044

chr7_+_142498832 3.855 ENSMUST00000078497.8
ENSMUST00000105953.3
ENSMUST00000179658.1
ENSMUST00000105954.3
ENSMUST00000105952.3
ENSMUST00000105955.1
ENSMUST00000074187.6
ENSMUST00000180152.1
ENSMUST00000105950.4
ENSMUST00000105957.3
ENSMUST00000169299.2
ENSMUST00000105958.3
ENSMUST00000105949.1
Tnnt3












troponin T3, skeletal, fast












chr9_+_72438534 3.813 ENSMUST00000034746.8
Mns1
meiosis-specific nuclear structural protein 1
chr4_-_140810646 3.708 ENSMUST00000026377.2
Padi3
peptidyl arginine deiminase, type III
chr11_-_116076986 3.528 ENSMUST00000153408.1
Unc13d
unc-13 homolog D (C. elegans)
chr2_-_69206146 3.449 ENSMUST00000127243.1
ENSMUST00000149643.1
ENSMUST00000167875.2
ENSMUST00000005365.8
Spc25



SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)



chr4_+_155791172 3.316 ENSMUST00000105593.1
Ankrd65
ankyrin repeat domain 65
chr6_-_136941887 3.250 ENSMUST00000111891.1
Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr16_+_17144600 3.232 ENSMUST00000115702.1
Ydjc
YdjC homolog (bacterial)
chr17_+_26917091 3.199 ENSMUST00000078961.4
Kifc5b
kinesin family member C5B
chr14_-_37110087 3.163 ENSMUST00000179488.1
2610528A11Rik
RIKEN cDNA 2610528A11 gene
chr4_-_135573623 3.085 ENSMUST00000105855.1
Grhl3
grainyhead-like 3 (Drosophila)
chr9_+_45138437 2.941 ENSMUST00000060125.5
Scn4b
sodium channel, type IV, beta
chr9_-_21963568 2.916 ENSMUST00000006397.5
Epor
erythropoietin receptor
chr8_-_88636117 2.824 ENSMUST00000034087.7
Snx20
sorting nexin 20
chr12_-_78906929 2.820 ENSMUST00000021544.7
Plek2
pleckstrin 2
chr11_-_102469839 2.795 ENSMUST00000103086.3
Itga2b
integrin alpha 2b
chr1_-_38664947 2.785 ENSMUST00000039827.7
ENSMUST00000027250.7
Aff3

AF4/FMR2 family, member 3

chr2_-_69206133 2.688 ENSMUST00000112320.1
Spc25
SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr3_-_90389884 2.680 ENSMUST00000029541.5
Slc27a3
solute carrier family 27 (fatty acid transporter), member 3
chr6_-_136941494 2.642 ENSMUST00000111892.1
Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr16_-_17144415 2.567 ENSMUST00000115709.1
Ccdc116
coiled-coil domain containing 116
chr6_-_136941694 2.455 ENSMUST00000032344.5
Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr13_+_113317084 2.439 ENSMUST00000136755.2
BC067074
cDNA sequence BC067074
chr14_-_54926784 2.378 ENSMUST00000022813.6
Efs
embryonal Fyn-associated substrate
chr5_+_144190284 2.363 ENSMUST00000060747.7
Bhlha15
basic helix-loop-helix family, member a15
chr8_-_105851981 2.355 ENSMUST00000040776.4
Cenpt
centromere protein T
chr11_+_87760533 2.352 ENSMUST00000039627.5
ENSMUST00000100644.3
Bzrap1

benzodiazepine receptor associated protein 1

chr6_+_71707561 2.315 ENSMUST00000121469.1
Reep1
receptor accessory protein 1
chr2_-_163397946 2.228 ENSMUST00000017961.4
ENSMUST00000109425.2
Jph2

junctophilin 2

chr11_-_116077606 2.195 ENSMUST00000106450.1
Unc13d
unc-13 homolog D (C. elegans)
chr1_+_171559186 2.189 ENSMUST00000004829.7
Cd244
CD244 natural killer cell receptor 2B4
chr14_-_78725089 2.186 ENSMUST00000074729.5
Dgkh
diacylglycerol kinase, eta
chr17_+_29090969 2.130 ENSMUST00000119901.1
Cdkn1a
cyclin-dependent kinase inhibitor 1A (P21)
chr7_+_18718075 2.035 ENSMUST00000108481.1
ENSMUST00000051973.8
Psg22

pregnancy-specific glycoprotein 22

chr7_+_103937382 2.003 ENSMUST00000098189.1
Olfr632
olfactory receptor 632
chr16_+_38458887 1.985 ENSMUST00000099816.2
Cd80
CD80 antigen
chr11_-_106301801 1.971 ENSMUST00000103071.3
Gh
growth hormone
chr7_+_130865835 1.969 ENSMUST00000075181.4
ENSMUST00000048180.5
Plekha1

pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1

chr7_+_47050628 1.939 ENSMUST00000010451.5
Tmem86a
transmembrane protein 86A
chr5_+_34999111 1.935 ENSMUST00000114283.1
Rgs12
regulator of G-protein signaling 12
chr5_-_30073554 1.924 ENSMUST00000026846.6
Tyms
thymidylate synthase
chr5_+_34999046 1.907 ENSMUST00000114281.1
Rgs12
regulator of G-protein signaling 12
chr14_-_70175397 1.868 ENSMUST00000143393.1
Pdlim2
PDZ and LIM domain 2
chr9_-_121792478 1.790 ENSMUST00000035110.4
Hhatl
hedgehog acyltransferase-like
chr4_-_156059414 1.713 ENSMUST00000184348.1
Ttll10
tubulin tyrosine ligase-like family, member 10
chr5_+_34999070 1.699 ENSMUST00000114280.1
Rgs12
regulator of G-protein signaling 12
chr7_+_24884809 1.674 ENSMUST00000156372.1
ENSMUST00000124035.1
Rps19

ribosomal protein S19

chr7_-_24545994 1.661 ENSMUST00000011776.6
Pinlyp
phospholipase A2 inhibitor and LY6/PLAUR domain containing
chr7_+_130865756 1.615 ENSMUST00000120441.1
Plekha1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr2_+_29889217 1.581 ENSMUST00000123335.1
Odf2
outer dense fiber of sperm tails 2
chr8_+_68880491 1.552 ENSMUST00000015712.8
Lpl
lipoprotein lipase
chr5_+_136057267 1.543 ENSMUST00000006303.4
ENSMUST00000156530.1
Upk3bl

uroplakin 3B-like

chr17_+_78882003 1.507 ENSMUST00000180880.1
Gm26637
predicted gene, 26637
chr10_+_21690845 1.496 ENSMUST00000071008.3
Gm5420
predicted gene 5420
chr5_+_34989473 1.454 ENSMUST00000114284.1
ENSMUST00000114285.1
Rgs12

regulator of G-protein signaling 12

chr2_+_29890063 1.445 ENSMUST00000028128.6
Odf2
outer dense fiber of sperm tails 2
chr3_+_96172327 1.392 ENSMUST00000076372.4
Sf3b4
splicing factor 3b, subunit 4
chr15_-_102350692 1.359 ENSMUST00000041208.7
Aaas
achalasia, adrenocortical insufficiency, alacrimia
chr9_-_120068263 1.353 ENSMUST00000064165.3
ENSMUST00000177637.1
Cx3cr1

chemokine (C-X3-C) receptor 1

chr7_+_19851994 1.336 ENSMUST00000172815.1
Gm19345
predicted gene, 19345
chr5_+_114707760 1.287 ENSMUST00000094441.4
Tchp
trichoplein, keratin filament binding
chr11_-_3527916 1.231 ENSMUST00000020718.4
Smtn
smoothelin
chr13_-_12520377 1.195 ENSMUST00000179308.1
Edaradd
EDAR (ectodysplasin-A receptor)-associated death domain
chr1_-_52232296 1.192 ENSMUST00000114512.1
Gls
glutaminase
chr3_-_92621173 1.192 ENSMUST00000170676.2
Lce6a
late cornified envelope 6A
chr11_-_99322943 1.183 ENSMUST00000038004.2
Krt25
keratin 25
chr2_+_10372426 1.171 ENSMUST00000114864.2
ENSMUST00000116594.2
ENSMUST00000041105.6
Sfmbt2


Scm-like with four mbt domains 2


chr6_+_134981998 1.134 ENSMUST00000167323.1
Apold1
apolipoprotein L domain containing 1
chr10_+_79822617 1.132 ENSMUST00000046833.4
Misp
mitotic spindle positioning
chr4_+_132351768 1.123 ENSMUST00000172202.1
Gm17300
predicted gene, 17300
chr4_-_42853888 1.114 ENSMUST00000107979.1
Gm12429
predicted gene 12429
chr1_+_133350510 1.107 ENSMUST00000094556.2
Ren1
renin 1 structural
chr13_-_98815408 1.106 ENSMUST00000040340.8
ENSMUST00000099277.4
ENSMUST00000179563.1
ENSMUST00000109403.1
Fcho2



FCH domain only 2



chr14_+_34086008 1.094 ENSMUST00000120077.1
Anxa8
annexin A8
chr5_+_136057138 1.085 ENSMUST00000111137.1
Upk3bl
uroplakin 3B-like
chr11_-_116168138 1.066 ENSMUST00000139020.1
ENSMUST00000103031.1
ENSMUST00000124828.1
Fbf1


Fas (TNFRSF6) binding factor 1


chr14_-_20496780 0.956 ENSMUST00000022353.3
Mss51
MSS51 mitochondrial translational activator
chr7_+_24884651 0.953 ENSMUST00000153451.2
ENSMUST00000108429.1
Rps19

ribosomal protein S19

chr13_-_22035589 0.919 ENSMUST00000091742.4
Hist1h2ah
histone cluster 1, H2ah
chr3_+_59925214 0.858 ENSMUST00000049476.2
C130079G13Rik
RIKEN cDNA C130079G13 gene
chr16_+_57353093 0.848 ENSMUST00000159816.1
Filip1l
filamin A interacting protein 1-like
chr2_+_86007778 0.845 ENSMUST00000062166.1
Olfr1032
olfactory receptor 1032
chr1_+_132880273 0.824 ENSMUST00000027706.3
Lrrn2
leucine rich repeat protein 2, neuronal
chr16_+_92478743 0.809 ENSMUST00000160494.1
2410124H12Rik
RIKEN cDNA 2410124H12 gene
chr10_-_130127055 0.808 ENSMUST00000074161.1
Olfr824
olfactory receptor 824
chr11_+_118476824 0.794 ENSMUST00000135383.2
Engase
endo-beta-N-acetylglucosaminidase
chr4_-_129641060 0.794 ENSMUST00000046425.9
ENSMUST00000133803.1
Txlna

taxilin alpha

chr19_-_10974664 0.769 ENSMUST00000072748.6
Ms4a10
membrane-spanning 4-domains, subfamily A, member 10
chr15_+_100154379 0.736 ENSMUST00000023768.6
ENSMUST00000108971.2
Dip2b

DIP2 disco-interacting protein 2 homolog B (Drosophila)

chr3_-_19265007 0.735 ENSMUST00000091314.4
Pde7a
phosphodiesterase 7A
chr9_+_5298517 0.732 ENSMUST00000027015.5
Casp1
caspase 1
chr7_-_114927726 0.731 ENSMUST00000059737.2
Gm6816
predicted gene 6816
chr9_-_100486788 0.729 ENSMUST00000098458.3
Il20rb
interleukin 20 receptor beta
chr1_+_165485168 0.726 ENSMUST00000111440.1
ENSMUST00000027852.8
ENSMUST00000111439.1
Adcy10


adenylate cyclase 10


chr13_+_23574381 0.721 ENSMUST00000090776.4
Hist1h2ad
histone cluster 1, H2ad
chr1_+_55237177 0.688 ENSMUST00000061334.8
Mars2
methionine-tRNA synthetase 2 (mitochondrial)
chr7_+_24884611 0.683 ENSMUST00000108428.1
Rps19
ribosomal protein S19
chr7_+_75455534 0.683 ENSMUST00000147005.1
ENSMUST00000166315.1
Akap13

A kinase (PRKA) anchor protein 13

chr2_+_152962485 0.679 ENSMUST00000099197.2
ENSMUST00000103155.3
Ttll9

tubulin tyrosine ligase-like family, member 9

chr5_-_115194283 0.660 ENSMUST00000112113.1
Cabp1
calcium binding protein 1
chr10_+_110745433 0.648 ENSMUST00000174857.1
ENSMUST00000073781.5
ENSMUST00000173471.1
ENSMUST00000173634.1
E2f7



E2F transcription factor 7



chr14_-_118925314 0.643 ENSMUST00000004055.8
Dzip1
DAZ interacting protein 1
chr5_-_6876523 0.642 ENSMUST00000164784.1
Zfp804b
zinc finger protein 804B
chr11_-_94782500 0.623 ENSMUST00000162809.2
Tmem92
transmembrane protein 92
chr6_+_127446819 0.619 ENSMUST00000112191.1
Parp11
poly (ADP-ribose) polymerase family, member 11
chr15_-_98004634 0.613 ENSMUST00000131560.1
ENSMUST00000088355.5
Col2a1

collagen, type II, alpha 1

chr3_+_64081642 0.607 ENSMUST00000029406.4
Vmn2r1
vomeronasal 2, receptor 1
chr6_-_38837224 0.592 ENSMUST00000160962.1
Hipk2
homeodomain interacting protein kinase 2
chr12_-_74316394 0.584 ENSMUST00000110441.1
Gm11042
predicted gene 11042
chr14_-_70653081 0.550 ENSMUST00000062629.4
Npm2
nucleophosmin/nucleoplasmin 2
chr8_+_10006656 0.528 ENSMUST00000033892.7
Tnfsf13b
tumor necrosis factor (ligand) superfamily, member 13b
chr10_+_21593151 0.521 ENSMUST00000057341.4
1700020N01Rik
RIKEN cDNA 1700020N01 gene
chr1_-_79858627 0.491 ENSMUST00000027467.4
Serpine2
serine (or cysteine) peptidase inhibitor, clade E, member 2
chr10_+_56377300 0.491 ENSMUST00000068581.7
Gja1
gap junction protein, alpha 1
chr1_+_106861144 0.491 ENSMUST00000086701.6
ENSMUST00000112730.1
Serpinb5

serine (or cysteine) peptidase inhibitor, clade B, member 5

chr2_-_127521358 0.487 ENSMUST00000028850.8
ENSMUST00000103215.4
Kcnip3

Kv channel interacting protein 3, calsenilin

chr5_+_24100578 0.456 ENSMUST00000030841.5
ENSMUST00000163409.1
Klhl7

kelch-like 7

chr3_-_92573715 0.451 ENSMUST00000053107.4
Ivl
involucrin
chr6_+_128438757 0.444 ENSMUST00000144745.1
Gm10069
predicted gene 10069
chr11_+_116593687 0.442 ENSMUST00000153476.1
Aanat
arylalkylamine N-acetyltransferase
chr4_-_129640959 0.435 ENSMUST00000132217.1
ENSMUST00000130017.1
ENSMUST00000154105.1
Txlna


taxilin alpha


chr5_+_36204016 0.423 ENSMUST00000052224.5
Psapl1
prosaposin-like 1
chr7_+_141079125 0.420 ENSMUST00000159375.1
Pkp3
plakophilin 3
chr1_-_74194631 0.415 ENSMUST00000053389.4
Cxcr1
chemokine (C-X-C motif) receptor 1
chrX_+_74254782 0.407 ENSMUST00000119197.1
ENSMUST00000088313.4
Emd

emerin

chr2_+_136891501 0.395 ENSMUST00000141463.1
Slx4ip
SLX4 interacting protein
chr19_-_47138280 0.394 ENSMUST00000140512.1
ENSMUST00000035822.1
Calhm2

calcium homeostasis modulator 2

chr9_-_76567092 0.374 ENSMUST00000183437.1
Fam83b
family with sequence similarity 83, member B
chr9_-_114982739 0.370 ENSMUST00000053150.5
Gm9846
predicted gene 9846
chr7_+_24399921 0.363 ENSMUST00000108434.1
Smg9
smg-9 homolog, nonsense mediated mRNA decay factor (C. elegans)
chr15_-_98004695 0.347 ENSMUST00000023123.8
Col2a1
collagen, type II, alpha 1
chr8_-_111854278 0.341 ENSMUST00000034432.5
Cfdp1
craniofacial development protein 1
chr1_+_51289106 0.334 ENSMUST00000051572.6
Sdpr
serum deprivation response
chr11_-_95699143 0.328 ENSMUST00000062249.2
Gm9796
predicted gene 9796
chr9_+_24097996 0.322 ENSMUST00000133787.1
ENSMUST00000059650.4
Npsr1

neuropeptide S receptor 1

chr14_-_49066368 0.302 ENSMUST00000161504.1
Exoc5
exocyst complex component 5
chr1_-_193130201 0.293 ENSMUST00000085555.1
Diexf
digestive organ expansion factor homolog (zebrafish)
chr16_+_20717665 0.269 ENSMUST00000021405.7
Polr2h
polymerase (RNA) II (DNA directed) polypeptide H
chr10_+_94550852 0.268 ENSMUST00000148910.1
ENSMUST00000117460.1
Tmcc3

transmembrane and coiled coil domains 3

chr11_-_113209633 0.237 ENSMUST00000130373.1
4732490B19Rik
RIKEN cDNA 4732490B19 gene
chr4_+_148558422 0.225 ENSMUST00000017408.7
ENSMUST00000076022.6
Exosc10

exosome component 10

chr9_+_49518336 0.223 ENSMUST00000068730.3
Gm11149
predicted gene 11149
chr10_+_80622677 0.222 ENSMUST00000079773.6
Csnk1g2
casein kinase 1, gamma 2
chr1_+_161969284 0.216 ENSMUST00000160881.1
ENSMUST00000159648.1
Pigc

phosphatidylinositol glycan anchor biosynthesis, class C

chr1_+_161969179 0.212 ENSMUST00000111594.2
ENSMUST00000028021.6
Pigc

phosphatidylinositol glycan anchor biosynthesis, class C

chr12_-_26415256 0.209 ENSMUST00000020971.6
ENSMUST00000062149.4
Rnf144a

ring finger protein 144A

chr4_+_112232245 0.207 ENSMUST00000038455.5
ENSMUST00000170945.1
Skint3

selection and upkeep of intraepithelial T cells 3

chr16_-_20316750 0.200 ENSMUST00000182741.1
Cyp2ab1
cytochrome P450, family 2, subfamily ab, polypeptide 1
chr4_+_42318334 0.185 ENSMUST00000178192.1
Gm21598
predicted gene, 21598
chr18_+_66458587 0.183 ENSMUST00000025399.7
Pmaip1
phorbol-12-myristate-13-acetate-induced protein 1
chr19_+_46328179 0.176 ENSMUST00000026256.2
ENSMUST00000177667.1
Fbxl15

F-box and leucine-rich repeat protein 15

chr2_+_129100995 0.151 ENSMUST00000103205.4
ENSMUST00000028874.7
Polr1b

polymerase (RNA) I polypeptide B

chr15_-_98898483 0.150 ENSMUST00000023737.4
Dhh
desert hedgehog
chr6_-_118562226 0.132 ENSMUST00000112830.1
Ankrd26
ankyrin repeat domain 26
chr7_+_24399606 0.124 ENSMUST00000002280.4
Smg9
smg-9 homolog, nonsense mediated mRNA decay factor (C. elegans)
chr9_-_106158109 0.099 ENSMUST00000159809.1
ENSMUST00000162562.1
ENSMUST00000036382.6
ENSMUST00000112543.2
Glyctk



glycerate kinase



chr12_+_107488632 0.093 ENSMUST00000082269.2
3110018I06Rik
RIKEN cDNA 3110018I06 gene
chr7_-_28962265 0.091 ENSMUST00000068045.7
Actn4
actinin alpha 4
chr3_+_79885930 0.086 ENSMUST00000029567.8
Fam198b
family with sequence similarity 198, member B
chrX_+_136822781 0.074 ENSMUST00000113085.1
Plp1
proteolipid protein (myelin) 1
chr7_-_28962223 0.067 ENSMUST00000127210.1
Actn4
actinin alpha 4
chr9_-_106656081 0.064 ENSMUST00000023959.7
Grm2
glutamate receptor, metabotropic 2
chr5_-_138272786 0.060 ENSMUST00000161279.1
ENSMUST00000161647.1
Gal3st4

galactose-3-O-sulfotransferase 4

chrX_-_56549606 0.033 ENSMUST00000081133.4
Gm648
predicted gene 648
chr2_+_88817173 0.029 ENSMUST00000072057.1
Olfr1202
olfactory receptor 1202
chr16_+_91391721 0.024 ENSMUST00000160764.1
Gm21970
predicted gene 21970
chr15_-_102246439 0.023 ENSMUST00000063339.7
Rarg
retinoic acid receptor, gamma
chr7_+_82851963 0.006 ENSMUST00000179662.1
1700010L04Rik
RIKEN cDNA 1700010L04 gene
chr13_+_41148796 0.002 ENSMUST00000141292.1
Sycp2l
synaptonemal complex protein 2-like
chr7_+_5034118 0.001 ENSMUST00000076791.3
4632433K11Rik
RIKEN cDNA 4632433K11 gene

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
6.0 17.9 GO:0072382 minus-end-directed vesicle transport along microtubule(GO:0072382)
4.2 12.7 GO:0060217 hemangioblast cell differentiation(GO:0060217)
3.8 11.4 GO:0070488 neutrophil aggregation(GO:0070488)
2.6 10.6 GO:0002540 leukotriene production involved in inflammatory response(GO:0002540)
1.4 7.0 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
1.4 5.6 GO:0042222 interleukin-1 biosynthetic process(GO:0042222)
1.3 5.2 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
1.0 8.3 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
1.0 2.9 GO:0036018 response to erythropoietin(GO:0036017) cellular response to erythropoietin(GO:0036018) erythropoietin-mediated signaling pathway(GO:0038162)
0.8 6.6 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.8 3.3 GO:0060265 positive regulation of respiratory burst involved in inflammatory response(GO:0060265)
0.7 3.7 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.7 2.2 GO:0071613 granzyme B production(GO:0071613) regulation of granzyme B production(GO:0071661) positive regulation of granzyme B production(GO:0071663)
0.7 5.7 GO:0061789 dense core granule priming(GO:0061789)
0.7 4.7 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.5 1.9 GO:0046073 dTMP biosynthetic process(GO:0006231) dTMP metabolic process(GO:0046073)
0.5 4.1 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.4 1.7 GO:2001201 regulation of transforming growth factor-beta secretion(GO:2001201)
0.4 7.8 GO:0070986 left/right axis specification(GO:0070986)
0.4 2.2 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.4 1.8 GO:1903059 regulation of protein lipidation(GO:1903059)
0.3 1.6 GO:0055095 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.3 1.2 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.3 1.7 GO:0018094 protein polyglycylation(GO:0018094)
0.3 1.4 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.2 0.7 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.2 0.7 GO:0002884 regulation of type IV hypersensitivity(GO:0001807) negative regulation of acute inflammatory response to antigenic stimulus(GO:0002865) negative regulation of hypersensitivity(GO:0002884)
0.2 1.1 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
0.2 0.6 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.2 0.4 GO:0098759 response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
0.2 3.7 GO:0033327 Leydig cell differentiation(GO:0033327)
0.2 1.2 GO:0006543 glutamine catabolic process(GO:0006543)
0.2 3.4 GO:0099623 regulation of ventricular cardiac muscle cell membrane repolarization(GO:0060307) regulation of cardiac muscle cell membrane repolarization(GO:0099623)
0.2 3.1 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.2 2.1 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.1 2.4 GO:0051382 kinetochore assembly(GO:0051382)
0.1 2.3 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.1 9.6 GO:0007019 microtubule depolymerization(GO:0007019)
0.1 0.5 GO:0031296 B cell costimulation(GO:0031296)
0.1 2.2 GO:0046339 diacylglycerol metabolic process(GO:0046339) phosphatidic acid metabolic process(GO:0046473)
0.1 2.4 GO:0010832 negative regulation of myotube differentiation(GO:0010832)
0.1 1.3 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.1 0.5 GO:0061110 dense core granule biogenesis(GO:0061110)
0.1 0.7 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.1 0.4 GO:0002159 desmosome assembly(GO:0002159)
0.1 2.0 GO:0046641 positive regulation of alpha-beta T cell proliferation(GO:0046641)
0.1 0.3 GO:2000293 negative regulation of eating behavior(GO:1903999) regulation of defecation(GO:2000292) negative regulation of defecation(GO:2000293)
0.1 2.0 GO:0090031 positive regulation of steroid hormone biosynthetic process(GO:0090031)
0.1 1.0 GO:0060174 limb bud formation(GO:0060174)
0.1 3.9 GO:0003009 skeletal muscle contraction(GO:0003009)
0.1 0.6 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.1 2.8 GO:0035116 embryonic hindlimb morphogenesis(GO:0035116)
0.1 6.1 GO:0007052 mitotic spindle organization(GO:0007052)
0.1 0.8 GO:0006517 protein deglycosylation(GO:0006517)
0.1 0.2 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.1 0.6 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.1 0.2 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.0 1.4 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 1.1 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 1.2 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.0 2.7 GO:1902017 regulation of cilium assembly(GO:1902017)
0.0 2.8 GO:0070527 platelet aggregation(GO:0070527)
0.0 0.3 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.4 GO:0042435 indole-containing compound biosynthetic process(GO:0042435)
0.0 0.7 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 0.4 GO:0060736 prostate gland growth(GO:0060736)
0.0 1.1 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 2.1 GO:0120034 positive regulation of plasma membrane bounded cell projection assembly(GO:0120034)
0.0 0.2 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.4 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 2.7 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
0.0 2.2 GO:0098869 cellular oxidant detoxification(GO:0098869)
0.0 2.4 GO:0006334 nucleosome assembly(GO:0006334)
0.0 5.7 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.5 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 2.0 GO:0051028 mRNA transport(GO:0051028)
0.0 1.6 GO:0006342 chromatin silencing(GO:0006342)
0.0 0.7 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 0.4 GO:0019236 response to pheromone(GO:0019236)
0.0 0.2 GO:0010917 negative regulation of mitochondrial membrane potential(GO:0010917)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
4.2 12.7 GO:0033193 Lsd1/2 complex(GO:0033193)
1.0 6.1 GO:0031262 Ndc80 complex(GO:0031262)
1.0 4.8 GO:0000235 astral microtubule(GO:0000235)
0.9 18.3 GO:0031616 spindle pole centrosome(GO:0031616)
0.7 5.2 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.7 2.1 GO:0070557 PCNA-p21 complex(GO:0070557)
0.7 10.6 GO:0005641 nuclear envelope lumen(GO:0005641)
0.5 5.7 GO:0033093 Weibel-Palade body(GO:0033093)
0.4 1.1 GO:0098835 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835)
0.3 9.6 GO:0001533 cornified envelope(GO:0001533)
0.2 2.2 GO:0030314 junctional membrane complex(GO:0030314)
0.2 3.9 GO:0005861 troponin complex(GO:0005861)
0.2 2.9 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.2 0.7 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.2 7.0 GO:0097440 apical dendrite(GO:0097440)
0.1 8.9 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 20.2 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.1 7.6 GO:0000786 nucleosome(GO:0000786)
0.1 4.4 GO:0098636 protein complex involved in cell adhesion(GO:0098636)
0.1 1.9 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 2.8 GO:0031901 early endosome membrane(GO:0031901)
0.1 0.4 GO:0005914 spot adherens junction(GO:0005914)
0.1 1.0 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 1.6 GO:0042627 chylomicron(GO:0042627)
0.1 3.7 GO:0097539 ciliary transition fiber(GO:0097539)
0.1 11.7 GO:0031225 anchored component of membrane(GO:0031225)
0.1 3.2 GO:0005871 kinesin complex(GO:0005871)
0.1 0.5 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 4.6 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 1.1 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 3.6 GO:0032587 ruffle membrane(GO:0032587)
0.0 1.7 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.9 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.4 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.4 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 1.2 GO:0016235 aggresome(GO:0016235)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 2.0 GO:0005643 nuclear pore(GO:0005643)
0.0 1.1 GO:0031902 late endosome membrane(GO:0031902)
0.0 1.8 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.3 GO:0000145 exocyst(GO:0000145)
0.0 3.4 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.7 GO:0045178 basal part of cell(GO:0045178)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.5 10.6 GO:0004051 arachidonate 5-lipoxygenase activity(GO:0004051)
1.4 11.4 GO:0050786 Toll-like receptor 4 binding(GO:0035662) RAGE receptor binding(GO:0050786)
1.0 8.3 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.8 6.6 GO:0002951 leukotriene-C(4) hydrolase(GO:0002951)
0.7 3.7 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.7 2.1 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.6 17.0 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.6 2.3 GO:0031849 olfactory receptor binding(GO:0031849)
0.6 1.7 GO:0070737 protein-glycine ligase activity, elongating(GO:0070737)
0.6 2.8 GO:0070051 fibrinogen binding(GO:0070051)
0.6 3.9 GO:0031013 troponin C binding(GO:0030172) calcium-dependent ATPase activity(GO:0030899) troponin I binding(GO:0031013)
0.4 2.9 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.3 1.4 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.3 2.7 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.3 4.1 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.3 2.0 GO:0045545 syndecan binding(GO:0045545)
0.2 5.2 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.2 2.0 GO:0005131 growth hormone receptor binding(GO:0005131)
0.2 0.7 GO:0042015 interleukin-20 binding(GO:0042015)
0.2 1.7 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.2 12.7 GO:0070888 E-box binding(GO:0070888)
0.2 7.5 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.2 1.2 GO:0004359 glutaminase activity(GO:0004359)
0.2 2.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.2 0.7 GO:0004825 methionine-tRNA ligase activity(GO:0004825)
0.2 2.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 0.4 GO:0019959 interleukin-8 binding(GO:0019959)
0.1 1.9 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 1.0 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 6.6 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 0.4 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.1 3.3 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.1 8.0 GO:0003777 microtubule motor activity(GO:0003777)
0.1 0.5 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.1 2.2 GO:0042288 MHC class I protein binding(GO:0042288)
0.1 2.8 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 8.1 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 1.9 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 1.6 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 1.2 GO:0005123 death receptor binding(GO:0005123)
0.1 0.7 GO:0050700 CARD domain binding(GO:0050700)
0.0 2.6 GO:0004601 peroxidase activity(GO:0004601)
0.0 4.7 GO:0004743 phosphoglycerate kinase activity(GO:0004618) phosphoglycerate mutase activity(GO:0004619) pyruvate kinase activity(GO:0004743)
0.0 1.1 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.7 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 7.7 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.4 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.6 GO:0046790 virion binding(GO:0046790)
0.0 0.3 GO:0034511 U3 snoRNA binding(GO:0034511)
0.0 0.3 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.4 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.4 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.4 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 3.2 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 2.6 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 1.1 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.1 GO:0005113 patched binding(GO:0005113)
0.0 2.4 GO:0008301 DNA binding, bending(GO:0008301)
0.0 1.3 GO:0005549 odorant binding(GO:0005549)
0.0 3.5 GO:0042393 histone binding(GO:0042393)
0.0 1.2 GO:0019905 syntaxin binding(GO:0019905)
0.0 2.4 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.3 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.7 GO:0030145 manganese ion binding(GO:0030145)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 10.5 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.2 2.1 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.2 15.2 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.1 4.3 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.1 2.8 PID_INTEGRIN_CS_PATHWAY Integrin family cell surface interactions
0.1 2.9 PID_EPO_PATHWAY EPO signaling pathway
0.1 3.0 PID_PLK1_PATHWAY PLK1 signaling events
0.0 3.6 PID_PI3KCI_PATHWAY Class I PI3K signaling events
0.0 2.0 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.0 0.7 PID_ANTHRAX_PATHWAY Cellular roles of Anthrax toxin
0.0 2.6 PID_E2F_PATHWAY E2F transcription factor network
0.0 1.0 PID_INTEGRIN1_PATHWAY Beta1 integrin cell surface interactions
0.0 0.6 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.4 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.5 PID_ATF2_PATHWAY ATF-2 transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 17.9 REACTOME_KINESINS Genes involved in Kinesins
0.2 5.6 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.2 2.8 REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.2 6.6 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.1 2.0 REACTOME_CD28_DEPENDENT_VAV1_PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 1.9 REACTOME_G1_S_SPECIFIC_TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 8.5 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 2.1 REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.1 3.3 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 1.6 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 1.4 REACTOME_NEP_NS2_INTERACTS_WITH_THE_CELLULAR_EXPORT_MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.1 0.7 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 2.2 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 9.0 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.7 REACTOME_MRNA_SPLICING_MINOR_PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 6.2 REACTOME_G_ALPHA_I_SIGNALLING_EVENTS Genes involved in G alpha (i) signalling events
0.0 0.7 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 1.4 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.5 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.0 0.5 REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.4 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.0 1.0 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.3 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.4 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)