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GSE58827: Dynamics of the Mouse Liver

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Results for Vsx1_Uncx_Prrx2_Shox2_Noto

Z-value: 0.83

Motif logo

Transcription factors associated with Vsx1_Uncx_Prrx2_Shox2_Noto

Gene Symbol Gene ID Gene Info
ENSMUSG00000033080.8 visual system homeobox 1
ENSMUSG00000029546.11 UNC homeobox
ENSMUSG00000039476.7 paired related homeobox 2
ENSMUSG00000027833.10 short stature homeobox 2
ENSMUSG00000068302.7 notochord homeobox

Activity-expression correlation:

Activity profile of Vsx1_Uncx_Prrx2_Shox2_Noto motif

Sorted Z-values of Vsx1_Uncx_Prrx2_Shox2_Noto motif

Promoter Log-likelihood Transcript Gene Gene Info
chr15_-_34356421 5.87 ENSMUST00000179647.1
RIKEN cDNA 9430069I07 gene
chr14_+_27000362 5.85 ENSMUST00000035433.8
homeobox gene expressed in ES cells
chr2_-_168767029 5.48 ENSMUST00000075044.3
sal-like 4 (Drosophila)
chr2_-_168767136 5.21 ENSMUST00000029061.5
ENSMUST00000103074.1
sal-like 4 (Drosophila)
chr15_-_79285502 4.80 ENSMUST00000165408.1
BAI1-associated protein 2-like 2
chr3_-_14778452 4.11 ENSMUST00000094365.4
carbonic anhydrase 1
chr15_-_79285470 3.86 ENSMUST00000170955.1
BAI1-associated protein 2-like 2
chr12_+_109545390 3.52 ENSMUST00000146701.1
maternally expressed 3
chr16_-_42340595 3.10 ENSMUST00000102817.4
growth associated protein 43
chr14_-_118052235 2.94 ENSMUST00000022725.2
dopachrome tautomerase
chr2_-_72813665 2.55 ENSMUST00000136807.1
ENSMUST00000148327.1
RIKEN cDNA 6430710C18 gene
chr11_-_87359011 2.30 ENSMUST00000055438.4
protein phosphatase 1E (PP2C domain containing)
chr2_+_25372315 2.28 ENSMUST00000028329.6
ENSMUST00000114293.2
ENSMUST00000100323.2
suppressor APC domain containing 2
chr11_+_67200052 2.21 ENSMUST00000124516.1
ENSMUST00000018637.8
myosin, heavy polypeptide 1, skeletal muscle, adult
chr1_+_172555932 2.16 ENSMUST00000061835.3
V-set and immunoglobulin domain containing 8
chr5_+_34999070 2.14 ENSMUST00000114280.1
regulator of G-protein signaling 12
chr5_+_34999111 2.11 ENSMUST00000114283.1
regulator of G-protein signaling 12
chrX_+_133850980 2.07 ENSMUST00000033602.8
tenomodulin
chr5_+_34999046 2.03 ENSMUST00000114281.1
regulator of G-protein signaling 12
chr9_+_96258697 1.91 ENSMUST00000179416.1
transcription factor Dp 2
chr6_-_145865302 1.83 ENSMUST00000111703.1
basic helix-loop-helix family, member e41
chr10_-_45470201 1.83 ENSMUST00000079390.6
lin-28 homolog B (C. elegans)
chr3_-_116253467 1.80 ENSMUST00000090473.5
G-protein coupled receptor 88
chr6_-_30958990 1.73 ENSMUST00000101589.3
Kruppel-like factor 14
chr17_+_34592248 1.68 ENSMUST00000038149.6
pre B cell leukemia homeobox 2
chr15_-_66812593 1.66 ENSMUST00000100572.3
src-like adaptor
chrX_-_74246534 1.57 ENSMUST00000101454.2
ENSMUST00000033699.6
filamin, alpha
chrX_+_150547375 1.53 ENSMUST00000066337.6
ENSMUST00000112715.1
aminolevulinic acid synthase 2, erythroid
chr1_-_132390301 1.42 ENSMUST00000132435.1
transmembrane and coiled-coil domains 2
chr7_+_144838590 1.39 ENSMUST00000105898.1
fibroblast growth factor 3
chr6_+_6248659 1.39 ENSMUST00000181633.1
ENSMUST00000176283.1
ENSMUST00000175814.1
ENSMUST00000181192.1
predicted gene 20619
chr11_+_67200137 1.35 ENSMUST00000129018.1
myosin, heavy polypeptide 1, skeletal muscle, adult
chr17_+_46161021 1.33 ENSMUST00000024748.7
ENSMUST00000172170.1
GTP binding protein 2
chr4_-_24430838 1.30 ENSMUST00000183964.1
RP23-35K5.2
chrX_-_7978027 1.30 ENSMUST00000125418.1
GATA binding protein 1
chr13_+_23575753 1.25 ENSMUST00000105105.1
histone cluster 1, H3d
chrX_-_139871637 1.24 ENSMUST00000033811.7
ENSMUST00000087401.5
microrchidia 4
chr8_-_120228221 1.23 ENSMUST00000183235.1
RIKEN cDNA A330074K22 gene
chrX_+_56454871 1.19 ENSMUST00000039374.2
ENSMUST00000101553.2
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
chr2_+_152754156 1.18 ENSMUST00000010020.5
cytochrome c oxidase subunit IV isoform 2
chr3_-_100489324 1.17 ENSMUST00000061455.8
family with sequence similarity 46, member C
chr16_-_74411292 1.09 ENSMUST00000117200.1
roundabout homolog 2 (Drosophila)
chr6_-_102464667 1.08 ENSMUST00000032159.6
contactin 3
chr18_+_44104407 1.05 ENSMUST00000081271.5
serine peptidase inhibitor, Kazal type 11
chr2_+_84734050 1.03 ENSMUST00000090729.2
yippee-like 4 (Drosophila)
chr1_-_126830632 1.02 ENSMUST00000112583.1
ENSMUST00000094609.3
NCK-associated protein 5
chr1_-_78968079 1.01 ENSMUST00000049117.5
predicted pseudogene 5830
chr2_+_80638798 1.01 ENSMUST00000028382.6
ENSMUST00000124377.1
nucleoporin 35
chr1_+_40515362 0.99 ENSMUST00000027237.5
interleukin 18 receptor accessory protein
chr7_-_100855403 0.99 ENSMUST00000156855.1
RELT tumor necrosis factor receptor
chr14_+_80000292 0.98 ENSMUST00000088735.3
olfactomedin 4
chrX_+_9885622 0.97 ENSMUST00000067529.2
ENSMUST00000086165.3
synaptotagmin-like 5
chr17_-_31198958 0.96 ENSMUST00000114549.2
transmembrane protease, serine 3
chr5_+_90490714 0.96 ENSMUST00000042755.3
alpha fetoprotein
chr8_-_3624989 0.96 ENSMUST00000142431.1
Purkinje cell protein 2 (L7)
chr2_+_27165233 0.95 ENSMUST00000000910.6
dopamine beta hydroxylase
chr8_+_121116163 0.93 ENSMUST00000054691.6
forkhead box C2
chr2_+_86007778 0.93 ENSMUST00000062166.1
olfactory receptor 1032
chr6_-_138079916 0.91 ENSMUST00000171804.1
solute carrier family 15, member 5
chr19_-_55241236 0.90 ENSMUST00000069183.6
guanylate cyclase 2g
chr8_-_3625274 0.87 ENSMUST00000004749.6
Purkinje cell protein 2 (L7)
chr8_+_83666827 0.86 ENSMUST00000019608.5
prostaglandin E receptor 1 (subtype EP1)
chr4_+_34893772 0.86 ENSMUST00000029975.3
ENSMUST00000135871.1
ENSMUST00000108130.1
glycoprotein hormones, alpha subunit
chr3_+_122044428 0.85 ENSMUST00000013995.8
ATP-binding cassette, sub-family A (ABC1), member 4
chrX_+_159303266 0.85 ENSMUST00000112491.1
ribosomal protein S6 kinase polypeptide 3
chrX_-_150814265 0.83 ENSMUST00000026302.6
ENSMUST00000129768.1
ENSMUST00000112699.2
melanoma antigen, family D, 2
chr4_-_99654983 0.82 ENSMUST00000136525.1
predicted gene 12688
chr3_-_130730375 0.82 ENSMUST00000079085.6
ribosomal protein L34
chr2_-_164171113 0.78 ENSMUST00000045196.3
K+ voltage-gated channel, subfamily S, 1
chr3_+_55782500 0.77 ENSMUST00000075422.4
mab-21-like 1 (C. elegans)
chr7_-_115824699 0.77 ENSMUST00000169129.1
SRY-box containing gene 6
chr10_-_24092320 0.77 ENSMUST00000092654.2
trace amine-associated receptor 8B
chr6_+_134929118 0.77 ENSMUST00000185152.1
ENSMUST00000184504.1
RP23-45G16.5
chr13_+_8202885 0.75 ENSMUST00000139438.1
ENSMUST00000135574.1
adenosine deaminase, RNA-specific, B2
chr8_-_62123106 0.75 ENSMUST00000034052.6
ENSMUST00000034054.7
annexin A10
chr17_+_7025837 0.75 ENSMUST00000089120.5
predicted gene 1604b
chr17_+_12119274 0.74 ENSMUST00000024594.2
1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta)
chr19_-_15924560 0.74 ENSMUST00000162053.1
phosphoserine aminotransferase 1
chr3_-_50443603 0.73 ENSMUST00000029297.4
solute carrier family 7 (cationic amino acid transporter, y+ system), member 11
chr3_-_72967854 0.72 ENSMUST00000167334.1
sucrase isomaltase (alpha-glucosidase)
chr4_-_154636831 0.71 ENSMUST00000030902.6
ENSMUST00000105637.1
ENSMUST00000070313.7
ENSMUST00000105636.1
ENSMUST00000105638.2
ENSMUST00000097759.2
ENSMUST00000124771.1
PR domain containing 16
chr11_+_102604370 0.71 ENSMUST00000057893.5
frizzled homolog 2 (Drosophila)
chr8_-_31918203 0.71 ENSMUST00000073884.4
neuregulin 1
chr17_-_24073479 0.70 ENSMUST00000017090.5
potassium channel tetramerisation domain containing 5
chr6_+_125552948 0.69 ENSMUST00000112254.1
ENSMUST00000112253.1
ENSMUST00000001995.7
Von Willebrand factor homolog
chr3_+_90600203 0.68 ENSMUST00000001047.7
S100 calcium binding protein A3
chr12_+_102128718 0.68 ENSMUST00000159329.1
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr2_-_170194033 0.67 ENSMUST00000180625.1
predicted gene, 17619
chr17_-_45733843 0.67 ENSMUST00000178179.1
RIKEN cDNA 1600014C23 gene
chr12_-_11208948 0.67 ENSMUST00000049877.1
mesogenin 1
chr9_-_53975246 0.66 ENSMUST00000048409.7
ELMO/CED-12 domain containing 1
chr4_+_13751297 0.66 ENSMUST00000105566.2
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr2_-_72986716 0.65 ENSMUST00000112062.1
predicted gene 11084
chr5_-_148392810 0.65 ENSMUST00000138257.1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr3_+_108092789 0.64 ENSMUST00000058669.8
ENSMUST00000145101.1
guanine nucleotide binding protein, alpha transducing 2
chr7_-_45830776 0.62 ENSMUST00000107723.2
ENSMUST00000131384.1
glutamate-rich WD repeat containing 1
chr10_-_80421847 0.60 ENSMUST00000156244.1
transcription factor 3
chr11_+_67171027 0.59 ENSMUST00000170159.1
myosin, heavy polypeptide 2, skeletal muscle, adult
chr9_+_119063429 0.58 ENSMUST00000141185.1
ENSMUST00000126251.1
ENSMUST00000136561.1
villin-like
chr11_+_67171095 0.58 ENSMUST00000018641.7
myosin, heavy polypeptide 2, skeletal muscle, adult
chr3_+_108093109 0.58 ENSMUST00000151326.1
guanine nucleotide binding protein, alpha transducing 2
chr18_+_77332394 0.56 ENSMUST00000148341.1
lipoxygenase homology domains 1
chr10_+_88091070 0.55 ENSMUST00000048621.7
pro-melanin-concentrating hormone
chr5_+_13398688 0.55 ENSMUST00000125629.1
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr3_+_159839729 0.54 ENSMUST00000068952.5
wntless homolog (Drosophila)
chr4_+_19818722 0.54 ENSMUST00000035890.7
solute carrier family 7, (cationic amino acid transporter, y+ system) member 13
chr11_+_103133333 0.54 ENSMUST00000124928.1
ENSMUST00000062530.4
hexamethylene bis-acetamide inducible 2
chr7_-_37773555 0.54 ENSMUST00000176534.1
zinc finger protein 536
chr5_-_138170992 0.54 ENSMUST00000139983.1
minichromosome maintenance deficient 7 (S. cerevisiae)
chr19_-_5560570 0.53 ENSMUST00000025861.1
OVO homolog-like 1 (Drosophila)
chr15_+_92597104 0.53 ENSMUST00000035399.8
PDZ domain containing RING finger 4
chr18_+_24603952 0.52 ENSMUST00000025120.6
elongator acetyltransferase complex subunit 2
chr10_+_127420867 0.52 ENSMUST00000064793.6
R3H domain containing 2
chr14_-_110755100 0.52 ENSMUST00000078386.2
SLIT and NTRK-like family, member 6
chr4_-_4138432 0.51 ENSMUST00000070375.7
preproenkephalin
chr5_-_138171248 0.51 ENSMUST00000153867.1
minichromosome maintenance deficient 7 (S. cerevisiae)
chr8_+_107031218 0.51 ENSMUST00000034388.9
vacuolar protein sorting 4a (yeast)
chr6_+_123262107 0.51 ENSMUST00000032240.2
C-type lectin domain family 4, member d
chr13_-_97747373 0.50 ENSMUST00000123535.1
RIKEN cDNA 5330416C01 gene
chr2_+_4017727 0.50 ENSMUST00000177457.1
FERM domain containing 4A
chr13_+_118714678 0.50 ENSMUST00000022246.8
fibroblast growth factor 10
chr17_+_71019503 0.50 ENSMUST00000024847.7
myomesin 1
chr5_-_138171216 0.49 ENSMUST00000147920.1
minichromosome maintenance deficient 7 (S. cerevisiae)
chr3_+_125404072 0.49 ENSMUST00000173932.1
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr3_-_17230976 0.49 ENSMUST00000177874.1
predicted gene 5283
chr1_-_126830786 0.49 ENSMUST00000162646.1
NCK-associated protein 5
chr2_+_130012336 0.49 ENSMUST00000110299.2
transglutaminase 3, E polypeptide
chr3_-_126998408 0.49 ENSMUST00000182764.1
ENSMUST00000044443.8
ankyrin 2, brain
chrX_+_21484532 0.49 ENSMUST00000089188.2
angiotensin II receptor, type 2
chr9_+_24283433 0.48 ENSMUST00000154644.1
neuropeptide S receptor 1
chr17_+_71019548 0.48 ENSMUST00000073211.5
ENSMUST00000179759.1
myomesin 1
chr17_-_29888570 0.48 ENSMUST00000171691.1
MAM domain containing glycosylphosphatidylinositol anchor 1
chr3_-_88410295 0.47 ENSMUST00000056370.7
polyamine-modulated factor 1
chr13_-_97747399 0.47 ENSMUST00000144993.1
RIKEN cDNA 5330416C01 gene
chr8_-_24725762 0.46 ENSMUST00000171438.1
ENSMUST00000171611.1
ENSMUST00000033958.7
a disintegrin and metallopeptidase domain 3 (cyritestin)
chr17_-_48432723 0.45 ENSMUST00000046549.3
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2
chr8_+_4238733 0.45 ENSMUST00000110998.2
ENSMUST00000062686.4
mitogen-activated protein kinase kinase 7
chr11_+_103133303 0.44 ENSMUST00000107037.1
hexamethylene bis-acetamide inducible 2
chr7_-_46667375 0.44 ENSMUST00000107669.2
tryptophan hydroxylase 1
chr13_-_113663670 0.44 ENSMUST00000054650.4
heat shock protein 3
chr9_+_55541148 0.44 ENSMUST00000034869.4
insulin related protein 2 (islet 2)
chr17_+_49615104 0.44 ENSMUST00000162854.1
kinesin family member 6
chr13_-_114458720 0.43 ENSMUST00000022287.5
follistatin
chr18_+_54990280 0.43 ENSMUST00000181538.1
predicted gene 4221
chr5_-_66514815 0.42 ENSMUST00000161879.1
ENSMUST00000159357.1
amyloid beta (A4) precursor protein-binding, family B, member 2
chr17_+_17402672 0.42 ENSMUST00000115576.2
limb expression 1 homolog (chicken)
chr3_+_134236483 0.41 ENSMUST00000181904.1
ENSMUST00000053048.9
CXXC finger 4
chr18_-_24603464 0.41 ENSMUST00000154205.1
solute carrier family 39 (metal ion transporter), member 6
chr1_-_172027269 0.41 ENSMUST00000027837.6
ENSMUST00000111264.1
vang-like 2 (van gogh, Drosophila)
chr5_+_19907502 0.40 ENSMUST00000101558.3
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr18_-_24603791 0.39 ENSMUST00000070726.3
solute carrier family 39 (metal ion transporter), member 6
chr1_-_150164943 0.39 ENSMUST00000181308.1
predicted gene, 26687
chr11_+_76904475 0.39 ENSMUST00000142166.1
transmembrane and immunoglobulin domain containing 1
chr2_+_85979312 0.39 ENSMUST00000170610.1
olfactory receptor 1030
chr4_-_14621805 0.38 ENSMUST00000042221.7
solute carrier family 26, member 7
chr11_+_67277124 0.38 ENSMUST00000019625.5
myosin, heavy polypeptide 8, skeletal muscle, perinatal
chr10_+_128337761 0.38 ENSMUST00000005826.7
citrate synthase
chr18_-_54990124 0.38 ENSMUST00000064763.5
zinc finger protein 608
chr2_+_125068118 0.36 ENSMUST00000070353.3
solute carrier family 24, member 5
chr10_-_92375367 0.36 ENSMUST00000182870.1
predicted gene, 20757
chr12_+_38780284 0.36 ENSMUST00000162563.1
ENSMUST00000161164.1
ENSMUST00000160996.1
ets variant gene 1
chr4_-_149126688 0.35 ENSMUST00000030815.2
cortistatin
chr7_-_5014645 0.35 ENSMUST00000165320.1
Flt3 interacting zinc finger protein 1
chr11_-_74724670 0.35 ENSMUST00000021091.8
platelet-activating factor acetylhydrolase, isoform 1b, subunit 1
chr12_-_40037387 0.35 ENSMUST00000146905.1
ADP-ribosylation factor-like 4A
chr9_+_65890237 0.34 ENSMUST00000045802.6
RIKEN cDNA 2810417H13 gene
chr11_+_52098681 0.34 ENSMUST00000020608.2
protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform
chr6_+_92816460 0.34 ENSMUST00000057977.3
RIKEN cDNA A730049H05 gene
chr15_-_102366314 0.34 ENSMUST00000078508.5
Sp7 transcription factor 7
chrX_-_143933204 0.33 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
doublecortin
chr5_-_103629279 0.33 ENSMUST00000031263.1
solute carrier family 10 (sodium/bile acid cotransporter family), member 6
chr3_+_125404292 0.33 ENSMUST00000144344.1
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr17_+_35533194 0.33 ENSMUST00000025273.8
psoriasis susceptibility 1 candidate 2 (human)
chr11_-_97700327 0.33 ENSMUST00000018681.7
polycomb group ring finger 2
chr4_-_14621494 0.32 ENSMUST00000149633.1
solute carrier family 26, member 7
chr8_-_5105232 0.32 ENSMUST00000023835.1
solute carrier family 10, member 2
chr15_-_100424092 0.32 ENSMUST00000154676.1
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chrX_-_102157065 0.32 ENSMUST00000056904.2
excision repair cross-complementing rodent repair deficiency complementation group 6 like
chr11_-_98053415 0.32 ENSMUST00000017544.2
SH3 and cysteine rich domain 2
chr5_+_14025305 0.32 ENSMUST00000073957.6
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr1_-_66945361 0.31 ENSMUST00000160100.1
myosin, light polypeptide 1
chrM_+_2743 0.31 ENSMUST00000082392.1
mitochondrially encoded NADH dehydrogenase 1
chr13_+_44121167 0.31 ENSMUST00000163056.1
ENSMUST00000159595.1
predicted gene 5083
chr13_-_102906046 0.31 ENSMUST00000171791.1
microtubule associated serine/threonine kinase family member 4
chr4_+_154960915 0.31 ENSMUST00000049621.6
hairy and enhancer of split 5 (Drosophila)
chrX_+_159708593 0.31 ENSMUST00000080394.6
SH3-domain kinase binding protein 1
chr15_+_21111452 0.31 ENSMUST00000075132.6
cadherin 12
chr15_-_8710409 0.30 ENSMUST00000157065.1
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chrX_-_134111852 0.30 ENSMUST00000033610.6
NADPH oxidase 1
chr2_+_153938218 0.30 ENSMUST00000109757.1
BPI fold containing family B, member 4
chrX_-_150589844 0.29 ENSMUST00000112725.1
ENSMUST00000112720.1
apurinic/apyrimidinic endonuclease 2
chr2_+_57997884 0.29 ENSMUST00000112616.1
ENSMUST00000166729.1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5
chr5_-_138187177 0.29 ENSMUST00000110937.1
ENSMUST00000139276.1
ENSMUST00000048698.7
ENSMUST00000123415.1
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr1_-_163725123 0.28 ENSMUST00000159679.1
methyltransferase like 11B
chr15_+_18818895 0.28 ENSMUST00000166873.2
cadherin 10
chr3_-_155055341 0.28 ENSMUST00000064076.3
TNNI3 interacting kinase
chr11_-_53470479 0.28 ENSMUST00000057722.2
predicted gene 9837
chr2_+_105130883 0.28 ENSMUST00000111098.1
ENSMUST00000111099.1
Wilms tumor 1 homolog
chr14_+_53324632 0.28 ENSMUST00000178100.1
T cell receptor alpha variable 7N-6
chr18_+_23415400 0.27 ENSMUST00000115832.2
ENSMUST00000047954.7
dystrobrevin alpha

Network of associatons between targets according to the STRING database.

First level regulatory network of Vsx1_Uncx_Prrx2_Shox2_Noto

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 6.3 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
1.0 2.9 GO:0006583 melanin biosynthetic process from tyrosine(GO:0006583)
0.8 7.7 GO:0030916 otic vesicle formation(GO:0030916)
0.6 1.8 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.6 10.7 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.5 2.1 GO:0061743 motor learning(GO:0061743)
0.5 4.2 GO:0016198 axon choice point recognition(GO:0016198)
0.4 1.3 GO:0030221 basophil differentiation(GO:0030221)
0.4 2.4 GO:0007199 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
0.4 8.7 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.3 1.3 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.3 1.0 GO:0006589 octopamine biosynthetic process(GO:0006589) octopamine metabolic process(GO:0046333)
0.3 0.9 GO:0003275 apoptotic process involved in outflow tract morphogenesis(GO:0003275) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.2 1.7 GO:0090520 sphingolipid mediated signaling pathway(GO:0090520)
0.2 0.6 GO:1901994 negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.2 1.8 GO:0010587 miRNA catabolic process(GO:0010587)
0.2 0.6 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.2 0.5 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.2 0.5 GO:1903774 mitotic cytokinesis checkpoint(GO:0044878) positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.2 1.7 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.2 1.5 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.2 2.3 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.2 1.8 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.1 0.7 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.1 0.4 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.1 0.5 GO:2000293 negative regulation of eating behavior(GO:1903999) regulation of defecation(GO:2000292) negative regulation of defecation(GO:2000293)
0.1 3.5 GO:0008340 determination of adult lifespan(GO:0008340)
0.1 0.3 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.1 0.5 GO:0021824 cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) facioacoustic ganglion development(GO:1903375)
0.1 0.8 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 0.5 GO:0021993 initiation of neural tube closure(GO:0021993)
0.1 0.5 GO:0015692 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.1 0.3 GO:2000978 auditory receptor cell fate determination(GO:0042668) negative regulation of forebrain neuron differentiation(GO:2000978)
0.1 0.5 GO:0038094 Fc-gamma receptor signaling pathway(GO:0038094)
0.1 0.7 GO:0045213 neurotransmitter receptor metabolic process(GO:0045213)
0.1 0.6 GO:0002326 B cell lineage commitment(GO:0002326)
0.1 0.3 GO:0060488 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.1 0.9 GO:0046884 follicle-stimulating hormone secretion(GO:0046884)
0.1 0.5 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.1 4.3 GO:0006730 one-carbon metabolic process(GO:0006730)
0.1 0.8 GO:0019532 oxalate transport(GO:0019532)
0.1 0.3 GO:2001076 negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302) regulation of metanephric ureteric bud development(GO:2001074) positive regulation of metanephric ureteric bud development(GO:2001076)
0.1 0.4 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.1 0.5 GO:0060005 vestibular reflex(GO:0060005)
0.1 0.5 GO:1903367 positive regulation of fear response(GO:1903367) positive regulation of behavioral fear response(GO:2000987)
0.1 1.2 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 1.4 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.1 1.2 GO:0001778 plasma membrane repair(GO:0001778)
0.1 0.8 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.1 0.8 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.1 0.3 GO:0051661 maintenance of centrosome location(GO:0051661)
0.1 0.2 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 1.0 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 0.9 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.1 0.3 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.1 0.2 GO:0060166 olfactory pit development(GO:0060166)
0.1 0.2 GO:0003162 atrioventricular node development(GO:0003162)
0.1 1.0 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.1 0.7 GO:2000671 regulation of motor neuron apoptotic process(GO:2000671)
0.1 0.5 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.1 0.1 GO:0035513 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.1 0.1 GO:1904956 regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.1 0.5 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.1 0.2 GO:1900149 positive regulation of Schwann cell migration(GO:1900149)
0.1 0.8 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.1 0.2 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729)
0.1 0.2 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.1 0.7 GO:0030853 negative regulation of granulocyte differentiation(GO:0030853)
0.1 1.0 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.1 0.2 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.1 1.0 GO:0006999 nuclear pore organization(GO:0006999)
0.0 0.2 GO:0051697 protein delipidation(GO:0051697)
0.0 0.7 GO:0007379 segment specification(GO:0007379)
0.0 0.2 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.0 0.5 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.2 GO:0021764 conditioned taste aversion(GO:0001661) amygdala development(GO:0021764)
0.0 0.2 GO:0010360 negative regulation of anion channel activity(GO:0010360)
0.0 1.3 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.6 GO:0015809 arginine transport(GO:0015809)
0.0 0.1 GO:0090365 regulation of mRNA modification(GO:0090365)
0.0 0.1 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221) olfactory nerve development(GO:0021553)
0.0 0.0 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.6 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.1 GO:2000481 positive regulation of cAMP-dependent protein kinase activity(GO:2000481)
0.0 0.2 GO:0051799 negative regulation of hair follicle development(GO:0051799)
0.0 0.1 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.3 GO:0016584 nucleosome positioning(GO:0016584)
0.0 1.0 GO:1904030 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.0 0.2 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.0 1.5 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.2 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.2 GO:0060023 soft palate development(GO:0060023)
0.0 0.4 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.2 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 0.1 GO:0033189 response to vitamin A(GO:0033189)
0.0 0.1 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.0 0.8 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.0 0.3 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0 1.0 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.2 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.4 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 2.4 GO:0016525 negative regulation of angiogenesis(GO:0016525)
0.0 1.4 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.0 0.1 GO:0016078 tRNA catabolic process(GO:0016078)
0.0 0.5 GO:0080111 DNA demethylation(GO:0080111)
0.0 0.4 GO:0030049 muscle filament sliding(GO:0030049)
0.0 0.2 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.1 GO:0050917 sensory perception of umami taste(GO:0050917)
0.0 0.2 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.0 0.0 GO:0033484 nitric oxide homeostasis(GO:0033484)
0.0 1.8 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.0 GO:0048880 medulla oblongata development(GO:0021550) sensory system development(GO:0048880)
0.0 0.1 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.1 GO:0042706 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.0 0.6 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 1.0 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 0.2 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.7 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.0 0.3 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0 0.2 GO:0050955 thermoception(GO:0050955)
0.0 0.4 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.6 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.3 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.0 0.2 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.5 GO:0031424 keratinization(GO:0031424)
0.0 0.4 GO:0045187 regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.0 0.4 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.6 GO:0051693 actin filament capping(GO:0051693)
0.0 0.2 GO:1902916 positive regulation of protein polyubiquitination(GO:1902916)
0.0 0.1 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.0 0.2 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.2 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 8.7 GO:0071439 clathrin complex(GO:0071439)
0.5 1.8 GO:0031523 Myb complex(GO:0031523)
0.3 1.0 GO:0060205 secretory granule lumen(GO:0034774) cytoplasmic membrane-bounded vesicle lumen(GO:0060205)
0.2 5.7 GO:0005859 muscle myosin complex(GO:0005859)
0.2 1.0 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.2 6.3 GO:0097440 apical dendrite(GO:0097440)
0.1 0.8 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 3.0 GO:0031527 filopodium membrane(GO:0031527)
0.1 0.5 GO:0032280 symmetric synapse(GO:0032280)
0.1 0.5 GO:0070826 paraferritin complex(GO:0070826)
0.1 1.5 GO:0042555 MCM complex(GO:0042555)
0.1 2.9 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 0.5 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.1 0.5 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 0.3 GO:0060187 cell pole(GO:0060187)
0.1 11.0 GO:0000792 heterochromatin(GO:0000792)
0.1 0.7 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 1.0 GO:0042581 specific granule(GO:0042581)
0.1 0.3 GO:0000235 astral microtubule(GO:0000235)
0.1 0.3 GO:0071438 invadopodium membrane(GO:0071438)
0.1 1.9 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 0.3 GO:0044301 climbing fiber(GO:0044301)
0.1 0.5 GO:0000815 ESCRT III complex(GO:0000815)
0.1 0.2 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.1 0.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 1.8 GO:0030673 axolemma(GO:0030673)
0.0 0.1 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.7 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 3.8 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.4 GO:0032982 myosin filament(GO:0032982)
0.0 0.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.5 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.2 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.7 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0071007 U2-type catalytic step 2 spliceosome(GO:0071007)
0.0 1.4 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.4 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.5 GO:0031430 M band(GO:0031430)
0.0 0.2 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.5 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 2.2 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.2 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.2 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.2 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.3 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 2.2 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 1.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.5 GO:0000786 nucleosome(GO:0000786)
0.0 0.3 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.5 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.1 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0071820 N-box binding(GO:0071820)
0.5 4.1 GO:0004064 arylesterase activity(GO:0004064)
0.5 1.5 GO:0016748 succinyltransferase activity(GO:0016748)
0.4 3.4 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.4 1.8 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.3 1.0 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.3 0.5 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.2 1.0 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.2 0.7 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.2 0.7 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.2 1.0 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.2 0.5 GO:0004945 angiotensin type II receptor activity(GO:0004945)
0.1 2.9 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.1 0.7 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.1 6.5 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 0.5 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.1 0.9 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 0.9 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.1 1.0 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 0.7 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.1 1.1 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 1.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.5 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 0.3 GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.1 1.0 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.1 0.5 GO:0031628 opioid receptor binding(GO:0031628)
0.1 1.1 GO:0004000 adenosine deaminase activity(GO:0004000)
0.1 0.6 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.1 1.3 GO:0008301 DNA binding, bending(GO:0008301)
0.1 0.5 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 0.6 GO:0070644 vitamin D response element binding(GO:0070644)
0.1 0.5 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 0.3 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.1 0.7 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.4 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 0.5 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.4 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.9 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.5 GO:0005000 vasopressin receptor activity(GO:0005000)
0.1 0.2 GO:0008457 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.1 1.0 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.1 0.4 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.3 GO:0031013 troponin I binding(GO:0031013)
0.0 0.3 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.8 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.6 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 1.2 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.2 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.1 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.0 0.3 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.0 0.3 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 1.5 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.8 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.3 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0008988 rRNA (adenine-N6-)-methyltransferase activity(GO:0008988)
0.0 0.2 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.0 0.2 GO:0070728 leucine binding(GO:0070728)
0.0 1.0 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 6.4 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 0.2 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.5 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.2 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 5.5 GO:0003774 motor activity(GO:0003774)
0.0 1.0 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.3 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.2 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 1.3 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 1.0 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.2 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 1.1 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.4 GO:0048185 activin binding(GO:0048185)
0.0 0.7 GO:0008483 transaminase activity(GO:0008483)
0.0 0.5 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 1.7 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.0 GO:1902121 lithocholic acid binding(GO:1902121)
0.0 0.5 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.7 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.3 GO:1990405 protein antigen binding(GO:1990405)
0.0 0.3 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 0.7 GO:0097602 cullin family protein binding(GO:0097602)
0.0 1.7 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.8 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 1.6 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.2 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.8 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.5 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 1.3 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 0.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 11.2 GO:0008134 transcription factor binding(GO:0008134)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.1 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.0 0.9 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.1 GO:0052724 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.0 0.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.2 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.0 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.0 0.2 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.5 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 1.2 GO:0005179 hormone activity(GO:0005179)
0.0 0.1 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 4.4 GO:0005543 phospholipid binding(GO:0005543)
0.0 0.1 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.7 GO:0005549 odorant binding(GO:0005549)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 9.4 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 2.5 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 2.6 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.1 1.4 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.5 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 1.1 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.9 PID ATR PATHWAY ATR signaling pathway
0.0 0.7 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.2 PID MYC PATHWAY C-MYC pathway
0.0 0.7 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 2.5 PID P73PATHWAY p73 transcription factor network
0.0 1.2 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.8 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.9 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.5 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.2 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.7 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.8 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.8 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.2 PID E2F PATHWAY E2F transcription factor network
0.0 0.8 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.4 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.7 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.5 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 1.7 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 0.5 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.5 PID HES HEY PATHWAY Notch-mediated HES/HEY network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.1 1.5 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 1.5 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 0.9 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.1 1.5 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 1.4 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 0.7 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 9.1 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.5 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.3 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 1.1 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 1.2 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 1.7 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.8 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.7 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.7 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 1.5 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.7 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 1.3 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 1.1 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 1.9 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.9 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.8 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.3 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.5 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.5 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.7 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 1.1 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.3 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.3 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 1.3 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.2 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.5 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription