Motif ID: Zbtb18

Z-value: 1.822


Transcription factors associated with Zbtb18:

Gene SymbolEntrez IDGene Name
Zbtb18 ENSMUSG00000063659.6 Zbtb18

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zbtb18mm10_v2_chr1_+_177445660_177445821-0.241.5e-01Click!


Activity profile for motif Zbtb18.

activity profile for motif Zbtb18


Sorted Z-values histogram for motif Zbtb18

Sorted Z-values for motif Zbtb18



Network of associatons between targets according to the STRING database.



First level regulatory network of Zbtb18

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_-_111691002 19.738 ENSMUST00000034435.5
Ctrb1
chymotrypsinogen B1
chr4_-_141825997 17.633 ENSMUST00000102481.3
Cela2a
chymotrypsin-like elastase family, member 2A
chr8_-_105933832 13.182 ENSMUST00000034368.6
Ctrl
chymotrypsin-like
chr17_-_12675833 10.319 ENSMUST00000024596.8
Slc22a1
solute carrier family 22 (organic cation transporter), member 1
chr4_-_115496129 9.921 ENSMUST00000030487.2
Cyp4a14
cytochrome P450, family 4, subfamily a, polypeptide 14
chr2_-_28563362 9.888 ENSMUST00000028161.5
Cel
carboxyl ester lipase
chr1_-_150466165 9.824 ENSMUST00000162367.1
ENSMUST00000161611.1
ENSMUST00000161320.1
ENSMUST00000159035.1
Prg4



proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein)



chr6_-_41035501 9.374 ENSMUST00000031931.5
2210010C04Rik
RIKEN cDNA 2210010C04 gene
chr8_-_24576297 8.982 ENSMUST00000033953.7
ENSMUST00000121992.1
Ido2

indoleamine 2,3-dioxygenase 2

chr14_+_30886521 8.957 ENSMUST00000168782.1
Itih4
inter alpha-trypsin inhibitor, heavy chain 4
chr17_-_84682932 8.561 ENSMUST00000066175.3
Abcg5
ATP-binding cassette, sub-family G (WHITE), member 5
chr14_+_30886476 8.557 ENSMUST00000006703.6
ENSMUST00000078490.5
ENSMUST00000120269.2
Itih4


inter alpha-trypsin inhibitor, heavy chain 4


chr6_+_37530204 7.945 ENSMUST00000151256.1
Akr1d1
aldo-keto reductase family 1, member D1
chr6_+_78405148 7.782 ENSMUST00000023906.2
Reg2
regenerating islet-derived 2
chr7_-_14446651 7.776 ENSMUST00000125941.1
2810007J24Rik
RIKEN cDNA 2810007J24 gene
chr7_-_14446570 7.770 ENSMUST00000063509.4
2810007J24Rik
RIKEN cDNA 2810007J24 gene
chr6_+_37530173 7.448 ENSMUST00000040987.7
Akr1d1
aldo-keto reductase family 1, member D1
chr7_-_19699008 6.985 ENSMUST00000174355.1
ENSMUST00000172983.1
ENSMUST00000174710.1
ENSMUST00000167646.2
ENSMUST00000003066.9
ENSMUST00000174064.1
Apoe





apolipoprotein E





chr1_+_93006328 6.925 ENSMUST00000059676.4
Aqp12
aquaporin 12
chr14_+_37054818 6.705 ENSMUST00000120052.1
Lrit1
leucine-rich repeat, immunoglobulin-like and transmembrane domains 1
chr1_-_139781236 6.674 ENSMUST00000027612.8
ENSMUST00000111989.2
ENSMUST00000111986.2
Gm4788


predicted gene 4788


chr7_-_99695628 6.582 ENSMUST00000145381.1
Slco2b1
solute carrier organic anion transporter family, member 2b1
chr2_+_43555321 6.527 ENSMUST00000028223.2
Kynu
kynureninase (L-kynurenine hydrolase)
chr17_-_28560704 6.440 ENSMUST00000114785.1
ENSMUST00000025062.3
Clps

colipase, pancreatic

chr7_-_99695572 6.326 ENSMUST00000137914.1
Slco2b1
solute carrier organic anion transporter family, member 2b1
chr2_+_43555342 6.166 ENSMUST00000112826.1
ENSMUST00000050511.6
Kynu

kynureninase (L-kynurenine hydrolase)

chr7_+_44225430 5.896 ENSMUST00000075162.3
Klk1
kallikrein 1
chr12_-_103457195 5.466 ENSMUST00000044687.6
Ifi27l2b
interferon, alpha-inducible protein 27 like 2B
chr4_-_49506538 5.217 ENSMUST00000043056.2
Baat
bile acid-Coenzyme A: amino acid N-acyltransferase
chr17_-_45686120 5.091 ENSMUST00000143907.1
ENSMUST00000127065.1
Tmem63b

transmembrane protein 63b

chr7_-_99695809 5.004 ENSMUST00000107086.2
Slco2b1
solute carrier organic anion transporter family, member 2b1
chr12_-_103989950 4.951 ENSMUST00000120251.2
Serpina11
serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11
chr17_+_10840361 4.883 ENSMUST00000097413.3
Park2
Parkinson disease (autosomal recessive, juvenile) 2, parkin
chr9_-_103219823 4.870 ENSMUST00000168142.1
Trf
transferrin
chr17_-_45685973 4.837 ENSMUST00000145873.1
Tmem63b
transmembrane protein 63b
chr18_+_45268876 4.835 ENSMUST00000183850.1
ENSMUST00000066890.7
Kcnn2

potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2

chr14_-_31640878 4.790 ENSMUST00000167066.1
ENSMUST00000127204.2
ENSMUST00000022437.8
Hacl1


2-hydroxyacyl-CoA lyase 1


chr3_-_131303144 4.484 ENSMUST00000106337.2
Cyp2u1
cytochrome P450, family 2, subfamily u, polypeptide 1
chr12_-_103989917 4.464 ENSMUST00000151709.2
ENSMUST00000176246.1
ENSMUST00000074693.7
Serpina11


serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11


chr2_+_102706356 4.334 ENSMUST00000123759.1
ENSMUST00000111212.1
ENSMUST00000005220.4
Slc1a2


solute carrier family 1 (glial high affinity glutamate transporter), member 2


chr7_-_97417730 4.298 ENSMUST00000043077.7
Thrsp
thyroid hormone responsive
chr16_+_26581704 4.273 ENSMUST00000096129.2
ENSMUST00000166294.2
ENSMUST00000174202.1
ENSMUST00000023156.6
Il1rap



interleukin 1 receptor accessory protein



chr16_+_91269759 4.223 ENSMUST00000056882.5
Olig1
oligodendrocyte transcription factor 1
chr4_+_141242850 4.172 ENSMUST00000138096.1
ENSMUST00000006618.2
ENSMUST00000125392.1
Arhgef19


Rho guanine nucleotide exchange factor (GEF) 19


chr17_-_46487641 4.162 ENSMUST00000047034.8
Ttbk1
tau tubulin kinase 1
chr1_-_139858684 4.137 ENSMUST00000094489.3
Cfhr2
complement factor H-related 2
chr7_+_122671378 4.085 ENSMUST00000182563.1
Cacng3
calcium channel, voltage-dependent, gamma subunit 3
chr19_+_34290653 4.014 ENSMUST00000025691.5
ENSMUST00000112472.2
Fas

Fas (TNF receptor superfamily member 6)

chr11_+_99047311 3.976 ENSMUST00000140772.1
Igfbp4
insulin-like growth factor binding protein 4
chr19_+_41029275 3.919 ENSMUST00000051806.4
ENSMUST00000112200.1
Dntt

deoxynucleotidyltransferase, terminal

chr1_+_160978576 3.863 ENSMUST00000064725.5
Serpinc1
serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1
chr1_-_162866502 3.837 ENSMUST00000046049.7
Fmo1
flavin containing monooxygenase 1
chr9_+_44066993 3.732 ENSMUST00000034508.7
Usp2
ubiquitin specific peptidase 2
chr5_-_92328068 3.729 ENSMUST00000113093.3
Cxcl9
chemokine (C-X-C motif) ligand 9
chr3_-_108536466 3.713 ENSMUST00000048012.6
ENSMUST00000106626.2
ENSMUST00000106625.3
5330417C22Rik


RIKEN cDNA 5330417C22 gene


chr1_+_164796723 3.708 ENSMUST00000027861.4
Dpt
dermatopontin
chr6_-_35326123 3.606 ENSMUST00000051176.7
Fam180a
family with sequence similarity 180, member A
chr11_-_115062177 3.363 ENSMUST00000062787.7
Cd300e
CD300e antigen
chr10_+_63061582 3.320 ENSMUST00000020266.8
ENSMUST00000178684.1
Pbld1

phenazine biosynthesis-like protein domain containing 1

chr2_-_25500613 3.173 ENSMUST00000040042.4
C8g
complement component 8, gamma polypeptide
chr9_+_44067072 3.144 ENSMUST00000177054.1
Usp2
ubiquitin specific peptidase 2
chr17_-_32947389 3.110 ENSMUST00000075253.6
Cyp4f13
cytochrome P450, family 4, subfamily f, polypeptide 13
chr7_+_122671401 3.108 ENSMUST00000182095.1
Cacng3
calcium channel, voltage-dependent, gamma subunit 3
chr17_-_32947372 3.037 ENSMUST00000139353.1
Cyp4f13
cytochrome P450, family 4, subfamily f, polypeptide 13
chr17_-_7385305 3.031 ENSMUST00000070059.3
Gm9992
predicted gene 9992
chr12_-_30373358 3.027 ENSMUST00000021004.7
Sntg2
syntrophin, gamma 2
chr4_-_130279205 3.018 ENSMUST00000120126.2
Serinc2
serine incorporator 2
chr11_-_68386974 3.004 ENSMUST00000135141.1
Ntn1
netrin 1
chr13_+_58806564 2.989 ENSMUST00000109838.2
Ntrk2
neurotrophic tyrosine kinase, receptor, type 2
chr8_+_4134733 2.988 ENSMUST00000130372.1
Cd209g
CD209g antigen
chr4_-_116017854 2.972 ENSMUST00000049095.5
Faah
fatty acid amide hydrolase
chr7_-_114415128 2.909 ENSMUST00000163996.1
4933406I18Rik
RIKEN cDNA 4933406I18 gene
chr9_+_119357381 2.907 ENSMUST00000039610.8
Xylb
xylulokinase homolog (H. influenzae)
chr14_-_63509092 2.879 ENSMUST00000022522.8
Tdh
L-threonine dehydrogenase
chr4_-_130275542 2.859 ENSMUST00000154846.1
ENSMUST00000105996.1
Serinc2

serine incorporator 2

chr1_+_45311538 2.829 ENSMUST00000087883.6
Col3a1
collagen, type III, alpha 1
chr8_+_13435459 2.816 ENSMUST00000167071.1
ENSMUST00000167505.1
Tmem255b

transmembrane protein 255B

chr11_+_118428493 2.799 ENSMUST00000017590.2
C1qtnf1
C1q and tumor necrosis factor related protein 1
chr14_-_122913085 2.781 ENSMUST00000162164.1
ENSMUST00000110679.2
ENSMUST00000038075.5
Ggact


gamma-glutamylamine cyclotransferase


chr4_-_108032069 2.763 ENSMUST00000106709.2
Podn
podocan
chr4_-_108031938 2.723 ENSMUST00000106708.1
Podn
podocan
chr17_-_45686214 2.700 ENSMUST00000113523.2
Tmem63b
transmembrane protein 63b
chr11_+_87582201 2.693 ENSMUST00000133202.1
Sept4
septin 4
chr14_+_41105359 2.675 ENSMUST00000047286.6
Mat1a
methionine adenosyltransferase I, alpha
chr1_+_88070765 2.645 ENSMUST00000073772.4
Ugt1a9
UDP glucuronosyltransferase 1 family, polypeptide A9
chr5_+_135725713 2.615 ENSMUST00000127096.1
Por
P450 (cytochrome) oxidoreductase
chr17_-_13131791 2.588 ENSMUST00000084966.5
Unc93a
unc-93 homolog A (C. elegans)
chr4_-_130275523 2.558 ENSMUST00000146478.1
Serinc2
serine incorporator 2
chr19_-_42202150 2.512 ENSMUST00000018966.7
Sfrp5
secreted frizzled-related sequence protein 5
chr12_-_104013640 2.501 ENSMUST00000058464.4
Serpina9
serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 9
chrX_-_8018492 2.484 ENSMUST00000033503.2
Glod5
glyoxalase domain containing 5
chr6_-_23132981 2.475 ENSMUST00000031707.7
Aass
aminoadipate-semialdehyde synthase
chr7_+_43950614 2.449 ENSMUST00000072204.4
Klk1b8
kallikrein 1-related peptidase b8
chr5_-_108448882 2.362 ENSMUST00000031455.3
Mfsd7a
major facilitator superfamily domain containing 7A
chr18_-_32139570 2.362 ENSMUST00000171765.1
Proc
protein C
chr1_-_132139605 2.327 ENSMUST00000112362.2
Cdk18
cyclin-dependent kinase 18
chr1_+_88138364 2.315 ENSMUST00000014263.4
Ugt1a6a
UDP glucuronosyltransferase 1 family, polypeptide A6A
chr2_-_150904620 2.243 ENSMUST00000056149.8
Abhd12
abhydrolase domain containing 12
chr7_-_79848191 2.230 ENSMUST00000107392.1
Anpep
alanyl (membrane) aminopeptidase
chr8_-_4105764 2.223 ENSMUST00000138439.1
ENSMUST00000145007.1
Cd209f

CD209f antigen

chr5_+_135674572 2.210 ENSMUST00000153515.1
Por
P450 (cytochrome) oxidoreductase
chr2_-_27247260 2.192 ENSMUST00000102886.3
ENSMUST00000129975.1
Sardh

sarcosine dehydrogenase

chr12_+_14494561 2.192 ENSMUST00000052528.3
Gm9847
predicted pseudogene 9847
chr14_-_68582078 2.179 ENSMUST00000022641.7
Adamdec1
ADAM-like, decysin 1
chr3_+_146597077 2.144 ENSMUST00000029837.7
ENSMUST00000121133.1
Uox

urate oxidase

chr18_-_12862341 2.129 ENSMUST00000121888.1
Osbpl1a
oxysterol binding protein-like 1A
chr4_+_20007938 2.121 ENSMUST00000125799.1
ENSMUST00000121491.1
Ttpa

tocopherol (alpha) transfer protein

chr5_-_38491948 2.111 ENSMUST00000129099.1
Slc2a9
solute carrier family 2 (facilitated glucose transporter), member 9
chr17_-_12868126 2.107 ENSMUST00000089015.3
Mas1
MAS1 oncogene
chr11_-_74925925 2.104 ENSMUST00000121738.1
Srr
serine racemase
chr14_+_31641051 2.091 ENSMUST00000090147.6
Btd
biotinidase
chrX_-_162643575 2.063 ENSMUST00000101102.1
Reps2
RALBP1 associated Eps domain containing protein 2
chr9_-_36797303 2.055 ENSMUST00000115086.5
Ei24
etoposide induced 2.4 mRNA
chr7_+_145300806 2.044 ENSMUST00000033386.5
Mrgprf
MAS-related GPR, member F
chr13_+_30336433 2.000 ENSMUST00000066412.7
Agtr1a
angiotensin II receptor, type 1a
chr6_+_91156665 1.999 ENSMUST00000041736.4
Hdac11
histone deacetylase 11
chr6_-_129237948 1.984 ENSMUST00000181238.1
ENSMUST00000180379.1
2310001H17Rik

RIKEN cDNA 2310001H17 gene

chr1_-_132139666 1.983 ENSMUST00000027697.5
Cdk18
cyclin-dependent kinase 18
chr6_+_91156772 1.981 ENSMUST00000143621.1
Hdac11
histone deacetylase 11
chr11_+_118428203 1.975 ENSMUST00000124861.1
C1qtnf1
C1q and tumor necrosis factor related protein 1
chr7_+_126950518 1.951 ENSMUST00000106335.1
ENSMUST00000146017.1
Sez6l2

seizure related 6 homolog like 2

chr2_-_65239092 1.902 ENSMUST00000156643.1
Cobll1
Cobl-like 1
chr19_+_43838803 1.899 ENSMUST00000099413.2
Gm10768
predicted gene 10768
chr7_+_126950687 1.879 ENSMUST00000106333.1
Sez6l2
seizure related 6 homolog like 2
chr12_+_85288591 1.859 ENSMUST00000059341.4
Zc2hc1c
zinc finger, C2HC-type containing 1C
chr7_+_145300889 1.856 ENSMUST00000117718.1
Mrgprf
MAS-related GPR, member F
chr15_+_31568791 1.816 ENSMUST00000162532.1
Cmbl
carboxymethylenebutenolidase-like (Pseudomonas)
chr14_+_41151442 1.815 ENSMUST00000047095.2
Mbl1
mannose-binding lectin (protein A) 1
chr12_+_29938036 1.810 ENSMUST00000122328.1
ENSMUST00000118321.1
Pxdn

peroxidasin homolog (Drosophila)

chrX_-_162643629 1.810 ENSMUST00000112334.1
Reps2
RALBP1 associated Eps domain containing protein 2
chr6_+_70726430 1.801 ENSMUST00000103410.1
Igkc
immunoglobulin kappa constant
chr4_+_60003438 1.801 ENSMUST00000107517.1
ENSMUST00000107520.1
Mup6

major urinary protein 6

chr11_+_101330605 1.791 ENSMUST00000103105.3
Aoc3
amine oxidase, copper containing 3
chr11_-_110095974 1.774 ENSMUST00000100287.2
Abca8a
ATP-binding cassette, sub-family A (ABC1), member 8a
chr18_+_20665250 1.745 ENSMUST00000075312.3
Ttr
transthyretin
chr11_-_109722214 1.743 ENSMUST00000020938.7
Fam20a
family with sequence similarity 20, member A
chr16_+_56204313 1.731 ENSMUST00000160116.1
ENSMUST00000069936.7
Impg2

interphotoreceptor matrix proteoglycan 2

chr12_-_113361232 1.700 ENSMUST00000103423.1
Ighg3
Immunoglobulin heavy constant gamma 3
chr6_+_91157373 1.692 ENSMUST00000155007.1
Hdac11
histone deacetylase 11
chr19_-_41385070 1.685 ENSMUST00000059672.7
Pik3ap1
phosphoinositide-3-kinase adaptor protein 1
chr11_+_80154103 1.675 ENSMUST00000021050.7
Adap2
ArfGAP with dual PH domains 2
chr9_-_58555129 1.674 ENSMUST00000165365.1
Cd276
CD276 antigen
chr6_-_50043657 1.667 ENSMUST00000177892.1
Gm21786
predicted gene, 21786
chr2_-_168734236 1.667 ENSMUST00000109175.2
Atp9a
ATPase, class II, type 9A
chr3_+_81932601 1.667 ENSMUST00000029649.2
Ctso
cathepsin O
chr17_+_79626669 1.666 ENSMUST00000086570.1
4921513D11Rik
RIKEN cDNA 4921513D11 gene
chr15_+_31568851 1.658 ENSMUST00000070918.6
Cmbl
carboxymethylenebutenolidase-like (Pseudomonas)
chr6_+_72355425 1.649 ENSMUST00000069695.2
ENSMUST00000132243.1
Tmem150a

transmembrane protein 150A

chr17_+_45686322 1.648 ENSMUST00000024734.7
Mrpl14
mitochondrial ribosomal protein L14
chr19_-_5394385 1.647 ENSMUST00000044527.4
Tsga10ip
testis specific 10 interacting protein
chr5_+_135353295 1.645 ENSMUST00000111180.2
ENSMUST00000065785.3
Trim50

tripartite motif-containing 50

chr3_-_88458876 1.632 ENSMUST00000147200.1
ENSMUST00000169222.1
Sema4a

sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A

chr4_-_44066960 1.625 ENSMUST00000173234.1
ENSMUST00000173274.1
Gne

glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase

chr17_-_57087729 1.618 ENSMUST00000071135.5
Tubb4a
tubulin, beta 4A class IVA
chr16_-_45693658 1.610 ENSMUST00000114562.2
ENSMUST00000036617.7
Tmprss7

transmembrane serine protease 7

chr14_-_20181773 1.603 ENSMUST00000024011.8
Kcnk5
potassium channel, subfamily K, member 5
chr17_-_23684019 1.599 ENSMUST00000085989.5
Cldn9
claudin 9
chr7_+_100009914 1.597 ENSMUST00000107084.1
Chrdl2
chordin-like 2
chr7_-_126898249 1.587 ENSMUST00000121532.1
ENSMUST00000032926.5
Tmem219

transmembrane protein 219

chr7_-_98361275 1.584 ENSMUST00000094161.4
ENSMUST00000164726.1
ENSMUST00000167405.1
Tsku


tsukushi


chr11_+_101331069 1.580 ENSMUST00000017316.6
Aoc3
amine oxidase, copper containing 3
chr11_-_68957445 1.574 ENSMUST00000108671.1
Arhgef15
Rho guanine nucleotide exchange factor (GEF) 15
chr11_-_53773187 1.564 ENSMUST00000170390.1
Gm17334
predicted gene, 17334
chr7_+_144175513 1.535 ENSMUST00000105900.1
Shank2
SH3/ankyrin domain gene 2
chr4_+_152008803 1.528 ENSMUST00000097773.3
Klhl21
kelch-like 21
chr15_-_97020322 1.524 ENSMUST00000166223.1
Slc38a4
solute carrier family 38, member 4
chr2_+_144594054 1.523 ENSMUST00000136628.1
Gm561
predicted gene 561
chr3_-_151749877 1.517 ENSMUST00000029671.7
Ifi44
interferon-induced protein 44
chr6_+_87428986 1.511 ENSMUST00000032125.5
Bmp10
bone morphogenetic protein 10
chr11_-_119086221 1.506 ENSMUST00000026665.7
Cbx4
chromobox 4
chr10_+_79970715 1.505 ENSMUST00000045085.1
Grin3b
glutamate receptor, ionotropic, NMDA3B
chr17_-_10840285 1.491 ENSMUST00000041463.6
Pacrg
PARK2 co-regulated
chr6_+_72598475 1.489 ENSMUST00000070597.6
ENSMUST00000176364.1
ENSMUST00000176168.1
Retsat


retinol saturase (all trans retinol 13,14 reductase)


chr5_-_24447587 1.479 ENSMUST00000127194.1
ENSMUST00000115033.1
ENSMUST00000123167.1
ENSMUST00000030799.8
Tmub1



transmembrane and ubiquitin-like domain containing 1



chr11_-_110095937 1.478 ENSMUST00000106664.3
ENSMUST00000046223.7
ENSMUST00000106662.1
Abca8a


ATP-binding cassette, sub-family A (ABC1), member 8a


chr7_-_98361310 1.474 ENSMUST00000165257.1
Tsku
tsukushi
chr2_-_132111440 1.469 ENSMUST00000128899.1
Slc23a2
solute carrier family 23 (nucleobase transporters), member 2
chr8_-_36732897 1.465 ENSMUST00000098826.3
Dlc1
deleted in liver cancer 1
chr15_+_44196135 1.456 ENSMUST00000038856.6
ENSMUST00000110289.3
Trhr

thyrotropin releasing hormone receptor

chr2_+_69135799 1.454 ENSMUST00000041865.7
Nostrin
nitric oxide synthase trafficker
chr15_+_85017138 1.445 ENSMUST00000023070.5
Upk3a
uroplakin 3A
chr10_-_18227473 1.437 ENSMUST00000174592.1
Ccdc28a
coiled-coil domain containing 28A
chr7_+_44012672 1.429 ENSMUST00000048945.4
Klk1b26
kallikrein 1-related petidase b26
chr5_-_120472763 1.427 ENSMUST00000052258.7
ENSMUST00000031594.6
Sdsl

serine dehydratase-like

chr11_-_119355484 1.427 ENSMUST00000100172.2
ENSMUST00000005173.4
Sgsh

N-sulfoglucosamine sulfohydrolase (sulfamidase)

chr11_+_118443471 1.426 ENSMUST00000133558.1
C1qtnf1
C1q and tumor necrosis factor related protein 1
chr10_-_89621253 1.422 ENSMUST00000020102.7
Slc17a8
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8
chr4_-_44073016 1.409 ENSMUST00000128439.1
ENSMUST00000140724.2
Gne

glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase

chr17_+_35439155 1.386 ENSMUST00000071951.6
ENSMUST00000078205.7
ENSMUST00000116598.3
ENSMUST00000076256.7
H2-Q7



histocompatibility 2, Q region locus 7



chr16_+_23107754 1.386 ENSMUST00000077605.5
ENSMUST00000115341.3
Eif4a2

eukaryotic translation initiation factor 4A2

chr6_+_147531392 1.382 ENSMUST00000111614.2
Ccdc91
coiled-coil domain containing 91
chr11_+_49609263 1.379 ENSMUST00000020617.2
Flt4
FMS-like tyrosine kinase 4
chr9_-_63399216 1.366 ENSMUST00000168665.1
2300009A05Rik
RIKEN cDNA 2300009A05 gene
chr13_+_56438343 1.338 ENSMUST00000021971.5
Slc25a48
solute carrier family 25, member 48
chr11_+_44400060 1.317 ENSMUST00000102796.3
ENSMUST00000170513.1
Il12b

interleukin 12b

chr6_+_17463749 1.315 ENSMUST00000115443.1
Met
met proto-oncogene
chr7_-_68353182 1.298 ENSMUST00000123509.1
ENSMUST00000129965.1
Gm16158

predicted gene 16158

chr11_+_119355551 1.285 ENSMUST00000050880.7
Slc26a11
solute carrier family 26, member 11
chr11_-_59182810 1.273 ENSMUST00000108793.2
Gjc2
gap junction protein, gamma 2
chr19_+_47865543 1.266 ENSMUST00000120645.1
Gsto2
glutathione S-transferase omega 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
5.1 15.4 GO:0030573 bile acid catabolic process(GO:0030573)
4.5 17.9 GO:0071718 sodium-independent icosanoid transport(GO:0071718)
4.2 12.7 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
2.9 8.6 GO:0010949 negative regulation of intestinal phytosterol absorption(GO:0010949) negative regulation of intestinal cholesterol absorption(GO:0045796) intestinal phytosterol absorption(GO:0060752) negative regulation of intestinal lipid absorption(GO:1904730)
2.8 8.3 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
2.3 7.0 GO:1905890 cellular response to very-low-density lipoprotein particle stimulus(GO:0090731) negative regulation of presynaptic membrane organization(GO:1901630) regulation of lipid transport across blood brain barrier(GO:1903000) positive regulation of lipid transport across blood brain barrier(GO:1903002) regulation of heparan sulfate binding(GO:1905853) positive regulation of heparan sulfate binding(GO:1905855) regulation of heparan sulfate proteoglycan binding(GO:1905858) positive regulation of heparan sulfate proteoglycan binding(GO:1905860) regulation of cellular response to very-low-density lipoprotein particle stimulus(GO:1905890)
1.2 9.9 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
1.2 9.8 GO:0045409 negative regulation of interleukin-6 biosynthetic process(GO:0045409)
1.2 4.8 GO:0046210 nitrate catabolic process(GO:0043602) nitric oxide catabolic process(GO:0046210) cellular organohalogen metabolic process(GO:0090345) cellular organofluorine metabolic process(GO:0090346)
1.2 8.4 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
1.1 10.3 GO:1901374 acetate ester transport(GO:1901374)
1.1 9.0 GO:0019441 tryptophan catabolic process(GO:0006569) tryptophan catabolic process to kynurenine(GO:0019441) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218)
1.1 3.3 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
1.1 4.3 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
1.0 2.9 GO:0042732 D-xylose metabolic process(GO:0042732)
0.8 2.5 GO:2000040 regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.8 2.5 GO:0006553 lysine metabolic process(GO:0006553)
0.8 18.9 GO:0061436 establishment of skin barrier(GO:0061436)
0.8 4.8 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.7 2.2 GO:0046462 monoacylglycerol metabolic process(GO:0046462)
0.7 3.0 GO:0099551 trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.7 0.7 GO:0051450 myoblast proliferation(GO:0051450) regulation of myoblast proliferation(GO:2000291)
0.7 2.2 GO:1901052 sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
0.7 2.9 GO:0006566 threonine metabolic process(GO:0006566)
0.7 4.3 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866)
0.7 4.8 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.7 6.2 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.7 5.4 GO:0070447 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.7 4.0 GO:0097527 necroptotic signaling pathway(GO:0097527)
0.7 2.0 GO:0002019 regulation of renal output by angiotensin(GO:0002019) phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.6 4.3 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.6 3.1 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.6 2.8 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.6 1.7 GO:0045077 negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.6 3.9 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.5 2.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.5 1.6 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.5 1.5 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.5 1.4 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.5 1.4 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.5 0.9 GO:0000255 allantoin metabolic process(GO:0000255)
0.5 1.4 GO:0001172 transcription, RNA-templated(GO:0001172)
0.4 1.3 GO:0010536 positive regulation of activation of Janus kinase activity(GO:0010536)
0.4 5.2 GO:0006544 glycine metabolic process(GO:0006544) taurine metabolic process(GO:0019530)
0.4 2.1 GO:0042360 vitamin E metabolic process(GO:0042360)
0.4 5.0 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.4 2.0 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.4 15.3 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.4 2.7 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.4 3.0 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.4 3.7 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.3 2.3 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.3 1.0 GO:1902569 negative regulation of activation of Janus kinase activity(GO:1902569)
0.3 6.9 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.3 1.2 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.3 2.1 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.3 3.8 GO:0070995 NADPH oxidation(GO:0070995)
0.3 4.7 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.3 0.9 GO:0061033 secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.3 1.4 GO:0060157 urinary bladder development(GO:0060157)
0.3 1.1 GO:0070889 platelet alpha granule organization(GO:0070889)
0.3 1.1 GO:0072014 proximal tubule development(GO:0072014)
0.3 1.4 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.3 1.1 GO:0002780 antimicrobial peptide biosynthetic process(GO:0002777) antibacterial peptide biosynthetic process(GO:0002780)
0.3 0.5 GO:0009957 epidermal cell fate specification(GO:0009957)
0.3 2.1 GO:0071494 cellular response to UV-C(GO:0071494)
0.3 0.8 GO:2000848 positive regulation of corticosteroid hormone secretion(GO:2000848)
0.3 1.3 GO:0009407 toxin catabolic process(GO:0009407) secondary metabolite catabolic process(GO:0090487)
0.3 4.3 GO:0046415 urate metabolic process(GO:0046415)
0.2 1.0 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.2 1.0 GO:0061113 pancreas morphogenesis(GO:0061113)
0.2 0.5 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.2 1.0 GO:0034769 basement membrane disassembly(GO:0034769)
0.2 5.4 GO:0001967 suckling behavior(GO:0001967)
0.2 0.9 GO:1905522 negative regulation of macrophage chemotaxis(GO:0010760) negative regulation of macrophage migration(GO:1905522)
0.2 0.8 GO:1905247 positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.2 1.7 GO:0002035 brain renin-angiotensin system(GO:0002035)
0.2 0.8 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.2 0.6 GO:0002223 stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.2 1.8 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.2 6.2 GO:2000311 regulation of AMPA receptor activity(GO:2000311)
0.2 3.2 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.2 1.4 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.2 0.8 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.2 0.6 GO:0045608 cardiac right atrium morphogenesis(GO:0003213) negative regulation of auditory receptor cell differentiation(GO:0045608)
0.2 1.1 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.2 4.7 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.2 0.2 GO:1900114 positive regulation of histone H3-K9 trimethylation(GO:1900114)
0.2 1.7 GO:0070327 thyroid hormone transport(GO:0070327)
0.2 5.7 GO:0006691 leukotriene metabolic process(GO:0006691)
0.2 2.8 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.2 3.1 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.2 4.4 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.2 1.5 GO:2000138 positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.2 0.7 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.2 0.6 GO:1904451 regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904451) positive regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904453)
0.2 20.6 GO:0007586 digestion(GO:0007586)
0.2 1.1 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.2 0.5 GO:2000563 tolerance induction to self antigen(GO:0002513) endocardial cushion fusion(GO:0003274) positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.2 0.6 GO:0019364 pyridine nucleotide catabolic process(GO:0019364)
0.2 2.1 GO:0070528 protein kinase C signaling(GO:0070528)
0.1 1.5 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.1 0.9 GO:0002042 cell migration involved in sprouting angiogenesis(GO:0002042)
0.1 3.3 GO:0071625 vocalization behavior(GO:0071625)
0.1 1.7 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134)
0.1 1.8 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 1.1 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 0.8 GO:0000042 protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.1 2.2 GO:0035814 negative regulation of renal sodium excretion(GO:0035814)
0.1 1.5 GO:0097264 self proteolysis(GO:0097264)
0.1 0.6 GO:0006702 androgen biosynthetic process(GO:0006702)
0.1 0.5 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.1 1.7 GO:0070166 enamel mineralization(GO:0070166)
0.1 5.6 GO:0014003 oligodendrocyte development(GO:0014003)
0.1 0.5 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.1 0.9 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1 0.8 GO:0099645 protein localization to postsynaptic specialization membrane(GO:0099633) neurotransmitter receptor localization to postsynaptic specialization membrane(GO:0099645)
0.1 1.1 GO:0006805 xenobiotic metabolic process(GO:0006805) response to xenobiotic stimulus(GO:0009410) cellular response to xenobiotic stimulus(GO:0071466)
0.1 2.9 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.1 0.8 GO:0070813 hydrogen sulfide metabolic process(GO:0070813)
0.1 1.1 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1 2.5 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.1 1.2 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.1 1.3 GO:0019532 oxalate transport(GO:0019532)
0.1 0.3 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.1 0.3 GO:1901994 negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.1 1.8 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.1 1.1 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1 1.1 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.1 1.0 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 1.8 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.1 1.6 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.1 0.3 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 0.4 GO:0099624 atrial cardiac muscle cell membrane repolarization(GO:0099624)
0.1 1.4 GO:0046548 retinal rod cell development(GO:0046548)
0.1 1.2 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.1 3.7 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.1 0.5 GO:0042776 response to glucagon(GO:0033762) mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 6.8 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.1 0.3 GO:0009405 pathogenesis(GO:0009405)
0.1 0.6 GO:0001880 Mullerian duct regression(GO:0001880)
0.1 1.9 GO:0051639 actin filament network formation(GO:0051639)
0.1 3.7 GO:0030199 collagen fibril organization(GO:0030199)
0.1 1.0 GO:0070986 left/right axis specification(GO:0070986)
0.1 0.2 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.1 0.5 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 0.2 GO:0015819 lysine transport(GO:0015819)
0.1 1.4 GO:0051205 protein insertion into membrane(GO:0051205)
0.1 1.3 GO:0042572 retinol metabolic process(GO:0042572)
0.1 1.0 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.1 3.9 GO:0048709 oligodendrocyte differentiation(GO:0048709)
0.1 0.3 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.1 0.6 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.1 0.6 GO:0007128 meiotic prophase I(GO:0007128) prophase(GO:0051324)
0.0 0.8 GO:0045019 negative regulation of nitric oxide biosynthetic process(GO:0045019) negative regulation of nitric oxide metabolic process(GO:1904406)
0.0 0.2 GO:0043328 protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.5 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.6 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.5 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.0 0.2 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.0 0.5 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.0 0.2 GO:0003273 cell migration involved in endocardial cushion formation(GO:0003273)
0.0 0.9 GO:0010801 negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0 1.5 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 1.3 GO:0010107 potassium ion import(GO:0010107)
0.0 0.7 GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
0.0 0.9 GO:0046326 positive regulation of glucose import(GO:0046326)
0.0 1.3 GO:0010644 cell communication by electrical coupling(GO:0010644)
0.0 0.8 GO:0001516 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.0 0.1 GO:1990859 cellular response to endothelin(GO:1990859)
0.0 0.6 GO:0042036 negative regulation of cytokine biosynthetic process(GO:0042036)
0.0 0.1 GO:1903660 transforming growth factor beta activation(GO:0036363) regulation of complement-dependent cytotoxicity(GO:1903659) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0 0.6 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.0 3.7 GO:0009062 fatty acid catabolic process(GO:0009062)
0.0 0.9 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.3 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.2 GO:0042420 dopamine catabolic process(GO:0042420)
0.0 1.0 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 1.6 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.2 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 1.8 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 0.7 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.0 0.1 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726)
0.0 1.1 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.9 GO:0006767 water-soluble vitamin metabolic process(GO:0006767)
0.0 0.4 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.6 GO:2001273 regulation of glucose import in response to insulin stimulus(GO:2001273)
0.0 0.3 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 1.0 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.6 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.0 0.1 GO:0060460 left lung morphogenesis(GO:0060460)
0.0 1.2 GO:0016239 positive regulation of macroautophagy(GO:0016239)
0.0 0.2 GO:2000507 positive regulation of feeding behavior(GO:2000253) positive regulation of energy homeostasis(GO:2000507)
0.0 0.6 GO:0035987 endodermal cell differentiation(GO:0035987)
0.0 0.5 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.2 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.8 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 0.5 GO:0039694 viral RNA genome replication(GO:0039694)
0.0 0.2 GO:0060763 mammary duct terminal end bud growth(GO:0060763)
0.0 1.9 GO:0070988 demethylation(GO:0070988)
0.0 1.5 GO:0034620 cellular response to unfolded protein(GO:0034620)
0.0 0.2 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.0 3.5 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.1 GO:1901727 regulation of histone deacetylase activity(GO:1901725) positive regulation of histone deacetylase activity(GO:1901727)
0.0 2.8 GO:0008360 regulation of cell shape(GO:0008360)
0.0 2.5 GO:0007416 synapse assembly(GO:0007416)
0.0 0.5 GO:0033198 response to ATP(GO:0033198)
0.0 1.5 GO:0030433 ubiquitin-dependent ERAD pathway(GO:0030433)
0.0 1.8 GO:0048017 inositol lipid-mediated signaling(GO:0048017)
0.0 1.0 GO:0007266 Rho protein signal transduction(GO:0007266)
0.0 0.8 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.2 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.9 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.6 GO:0007094 mitotic spindle assembly checkpoint(GO:0007094) spindle assembly checkpoint(GO:0071173)
0.0 1.2 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.7 GO:0051452 intracellular pH reduction(GO:0051452)
0.0 0.1 GO:2000360 negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.0 0.9 GO:0016525 negative regulation of angiogenesis(GO:0016525)
0.0 0.2 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.5 GO:0070613 regulation of protein processing(GO:0070613)
0.0 0.2 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.0 3.4 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.6 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.6 GO:0001541 ovarian follicle development(GO:0001541)
0.0 1.0 GO:0022900 electron transport chain(GO:0022900)
0.0 0.2 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0 0.2 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.7 GO:0060711 labyrinthine layer development(GO:0060711)
0.0 0.4 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.1 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.1 GO:0015862 uridine transport(GO:0015862)
0.0 0.3 GO:0090501 RNA phosphodiester bond hydrolysis(GO:0090501)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 8.6 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
1.6 4.9 GO:0099073 mitochondrion-derived vesicle(GO:0099073)
1.4 7.0 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.7 4.0 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.5 4.9 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.4 1.7 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.4 4.2 GO:0031983 vesicle lumen(GO:0031983)
0.4 1.1 GO:0098842 postsynaptic early endosome(GO:0098842)
0.4 1.4 GO:0120001 apical plasma membrane urothelial plaque(GO:0120001)
0.4 1.4 GO:0097450 astrocyte end-foot(GO:0097450)
0.3 10.1 GO:0042588 zymogen granule(GO:0042588)
0.3 1.4 GO:0035841 new growing cell tip(GO:0035841)
0.3 3.2 GO:0005579 membrane attack complex(GO:0005579)
0.3 2.7 GO:0097227 sperm annulus(GO:0097227)
0.3 1.0 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.2 21.2 GO:0009925 basal plasma membrane(GO:0009925)
0.2 0.7 GO:0036125 mitochondrial fatty acid beta-oxidation multienzyme complex(GO:0016507) fatty acid beta-oxidation multienzyme complex(GO:0036125)
0.2 1.5 GO:0005827 polar microtubule(GO:0005827)
0.2 2.8 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.2 0.6 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.2 0.6 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.2 1.8 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.2 1.6 GO:0033269 internode region of axon(GO:0033269)
0.2 0.5 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.2 1.0 GO:0071986 Ragulator complex(GO:0071986)
0.2 8.4 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 1.0 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1 1.4 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 0.6 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 0.5 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 4.3 GO:0030673 axolemma(GO:0030673)
0.1 4.8 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 0.7 GO:0002081 outer acrosomal membrane(GO:0002081)
0.1 0.5 GO:1990246 uniplex complex(GO:1990246)
0.1 0.5 GO:1990923 PET complex(GO:1990923)
0.1 0.8 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 1.5 GO:0005883 neurofilament(GO:0005883)
0.1 2.1 GO:0005922 connexin complex(GO:0005922)
0.1 0.3 GO:0002111 BRCA2-BRAF35 complex(GO:0002111)
0.1 1.5 GO:0035102 PRC1 complex(GO:0035102)
0.1 7.4 GO:0005581 collagen trimer(GO:0005581)
0.1 2.1 GO:0016363 nuclear matrix(GO:0016363)
0.1 1.5 GO:0097225 sperm midpiece(GO:0097225)
0.1 4.8 GO:0060076 excitatory synapse(GO:0060076)
0.1 0.4 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.1 1.5 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 0.5 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.1 0.2 GO:0000814 ESCRT II complex(GO:0000814)
0.1 0.6 GO:0045179 apical cortex(GO:0045179)
0.1 0.8 GO:0045095 keratin filament(GO:0045095)
0.1 0.6 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 1.2 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 0.5 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.0 2.5 GO:0016235 aggresome(GO:0016235)
0.0 0.7 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.1 GO:0005607 laminin-2 complex(GO:0005607)
0.0 0.6 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 4.1 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 8.2 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.9 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0061827 sperm head(GO:0061827)
0.0 5.3 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 21.5 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 1.1 GO:0000786 nucleosome(GO:0000786)
0.0 0.2 GO:0005916 fascia adherens(GO:0005916)
0.0 1.1 GO:0060077 inhibitory synapse(GO:0060077)
0.0 3.0 GO:0005901 caveola(GO:0005901)
0.0 0.2 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 1.6 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 1.0 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 8.5 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.8 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 3.2 GO:0072562 blood microparticle(GO:0072562)
0.0 4.1 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 85.2 GO:0005615 extracellular space(GO:0005615)
0.0 0.5 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 3.0 GO:0005802 trans-Golgi network(GO:0005802)
0.0 1.0 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.3 GO:0043196 varicosity(GO:0043196)
0.0 0.9 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.4 GO:0005834 heterotrimeric G-protein complex(GO:0005834) GTPase complex(GO:1905360)
0.0 0.3 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.3 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.0 0.8 GO:0000791 euchromatin(GO:0000791)
0.0 0.1 GO:0060473 cortical granule(GO:0060473)
0.0 17.9 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 17.0 GO:0005739 mitochondrion(GO:0005739)
0.0 1.2 GO:0045177 apical part of cell(GO:0045177)
0.0 0.4 GO:0005881 cytoplasmic microtubule(GO:0005881)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
5.1 15.4 GO:0047787 delta4-3-oxosteroid 5beta-reductase activity(GO:0047787)
3.4 10.3 GO:0005333 norepinephrine transmembrane transporter activity(GO:0005333)
3.3 9.9 GO:0004771 sterol esterase activity(GO:0004771)
3.2 12.7 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
3.0 9.0 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
2.3 7.0 GO:0046911 metal chelating activity(GO:0046911)
1.7 9.9 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
1.2 4.8 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
1.2 4.8 GO:0016708 nitric oxide dioxygenase activity(GO:0008941) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor(GO:0016708) iron-cytochrome-c reductase activity(GO:0047726)
1.1 3.4 GO:0052593 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
1.1 4.3 GO:0002114 interleukin-33 binding(GO:0002113) interleukin-33 receptor activity(GO:0002114)
1.1 8.4 GO:0003882 CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:0003882)
1.0 3.0 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.9 17.9 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.8 5.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.7 3.7 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.7 2.2 GO:0008480 sarcosine dehydrogenase activity(GO:0008480)
0.7 4.3 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.7 17.1 GO:0005540 hyaluronic acid binding(GO:0005540)
0.7 2.1 GO:0008431 vitamin E binding(GO:0008431)
0.7 3.5 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.7 4.9 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.6 3.0 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761)
0.6 4.1 GO:0001595 angiotensin receptor activity(GO:0001595)
0.6 2.8 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.5 4.8 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.5 2.1 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.5 3.1 GO:0036458 hepatocyte growth factor binding(GO:0036458)
0.5 1.5 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.5 2.4 GO:0070012 oligopeptidase activity(GO:0070012)
0.5 1.4 GO:0003968 RNA-directed 5'-3' RNA polymerase activity(GO:0003968)
0.4 4.0 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.4 1.3 GO:0019972 interleukin-12 binding(GO:0019972)
0.4 1.3 GO:0050610 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.4 2.0 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.4 11.4 GO:0030247 polysaccharide binding(GO:0030247)
0.4 3.8 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.4 5.2 GO:0102991 myristoyl-CoA hydrolase activity(GO:0102991)
0.4 1.1 GO:0030977 taurine binding(GO:0030977)
0.3 5.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.3 1.4 GO:0019809 spermidine binding(GO:0019809)
0.3 1.7 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.3 1.0 GO:0070540 stearic acid binding(GO:0070540)
0.3 1.0 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.3 8.6 GO:0017127 cholesterol transporter activity(GO:0017127)
0.3 2.1 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
0.2 3.0 GO:0097109 neuroligin family protein binding(GO:0097109)
0.2 1.8 GO:0050649 testosterone 6-beta-hydroxylase activity(GO:0050649)
0.2 2.1 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.2 85.4 GO:0008236 serine-type peptidase activity(GO:0008236)
0.2 3.2 GO:0019841 retinol binding(GO:0019841)
0.2 1.3 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.2 4.0 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.2 0.8 GO:0004568 chitinase activity(GO:0004568)
0.2 2.8 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.2 6.2 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.2 5.1 GO:0070330 aromatase activity(GO:0070330)
0.2 4.1 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.2 0.5 GO:0005119 smoothened binding(GO:0005119) hedgehog receptor activity(GO:0008158)
0.2 0.7 GO:0016508 long-chain-enoyl-CoA hydratase activity(GO:0016508) long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.2 0.9 GO:0071532 ankyrin repeat binding(GO:0071532)
0.2 1.4 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.2 1.5 GO:0031433 telethonin binding(GO:0031433)
0.1 11.8 GO:0005518 collagen binding(GO:0005518)
0.1 0.8 GO:1902944 aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902944)
0.1 2.1 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 0.8 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.1 5.0 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 2.5 GO:0017166 vinculin binding(GO:0017166)
0.1 1.0 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 0.9 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 0.6 GO:0042731 PH domain binding(GO:0042731)
0.1 0.9 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 0.5 GO:0001847 opsonin receptor activity(GO:0001847)
0.1 0.6 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.1 1.7 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 0.5 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.5 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 0.6 GO:0005113 patched binding(GO:0005113) laminin-1 binding(GO:0043237)
0.1 2.6 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 2.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.6 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 1.4 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.1 0.6 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.1 2.2 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.1 0.7 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 1.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 1.4 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.1 0.6 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.1 0.7 GO:0030368 interleukin-17 binding(GO:0019975) interleukin-17 receptor activity(GO:0030368)
0.1 0.3 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 1.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.9 GO:0005243 gap junction channel activity(GO:0005243)
0.1 0.9 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 1.7 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 1.6 GO:0001618 virus receptor activity(GO:0001618)
0.1 1.1 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 1.5 GO:0016594 glycine binding(GO:0016594)
0.1 1.5 GO:0005537 mannose binding(GO:0005537)
0.1 0.5 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 0.6 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.6 GO:0008428 ribonuclease inhibitor activity(GO:0008428)
0.1 0.8 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 1.3 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 0.4 GO:0032029 myosin tail binding(GO:0032029)
0.1 1.1 GO:0015250 water channel activity(GO:0015250)
0.1 0.9 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.1 2.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 0.2 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.1 0.8 GO:0008430 selenium binding(GO:0008430)
0.1 1.7 GO:0098988 G-protein coupled glutamate receptor activity(GO:0098988)
0.1 0.6 GO:0023029 MHC class Ib protein binding(GO:0023029)
0.1 1.0 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 1.7 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 1.7 GO:0032183 SUMO binding(GO:0032183)
0.1 1.7 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 2.7 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 0.5 GO:0034046 poly(G) binding(GO:0034046)
0.1 0.6 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.1 0.3 GO:0004111 creatine kinase activity(GO:0004111)
0.1 8.1 GO:0030332 cyclin binding(GO:0030332)
0.0 0.7 GO:0031386 protein tag(GO:0031386)
0.0 0.4 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.5 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 2.1 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.5 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.9 GO:0031005 filamin binding(GO:0031005)
0.0 1.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.2 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.0 1.3 GO:0008009 chemokine activity(GO:0008009)
0.0 5.3 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 1.8 GO:0050699 WW domain binding(GO:0050699)
0.0 0.2 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.0 1.0 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 2.5 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 0.5 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 1.3 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.8 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 1.1 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 1.3 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.2 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 3.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.6 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.4 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.3 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.1 GO:0046812 host cell surface binding(GO:0046812)
0.0 1.7 GO:1990782 protein tyrosine kinase binding(GO:1990782)
0.0 1.7 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.0 0.5 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.5 GO:0020037 heme binding(GO:0020037)
0.0 0.6 GO:0008308 voltage-gated anion channel activity(GO:0008308)
0.0 0.9 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.6 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.4 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.0 0.2 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313)
0.0 0.1 GO:0008527 taste receptor activity(GO:0008527)
0.0 1.0 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 2.7 GO:0061660 Atg12 activating enzyme activity(GO:0019778) Atg8-specific protease activity(GO:0019786) Atg12 conjugating enzyme activity(GO:0061651) Atg12 ligase activity(GO:0061660)
0.0 0.1 GO:0038100 nodal binding(GO:0038100)
0.0 0.7 GO:0000049 tRNA binding(GO:0000049)
0.0 0.6 GO:0036002 pre-mRNA binding(GO:0036002)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 17.0 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.3 3.8 SA_FAS_SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.2 48.4 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 3.9 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 4.0 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.1 2.0 SA_G1_AND_S_PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1 2.7 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.1 4.9 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.1 2.5 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.1 3.1 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.1 3.8 PID_IL1_PATHWAY IL1-mediated signaling events
0.1 4.2 PID_IL23_PATHWAY IL23-mediated signaling events
0.1 1.8 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.1 0.8 PID_IFNG_PATHWAY IFN-gamma pathway
0.1 3.9 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 0.5 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.1 4.1 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.1 0.6 PID_KIT_PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 0.8 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.1 0.6 PID_ALK2_PATHWAY ALK2 signaling events
0.0 1.1 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 2.8 NABA_COLLAGENS Genes encoding collagen proteins
0.0 9.8 NABA_CORE_MATRISOME Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.0 2.7 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.6 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.0 3.7 PID_CMYB_PATHWAY C-MYB transcription factor network
0.0 0.5 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.0 1.8 PID_IL4_2PATHWAY IL4-mediated signaling events
0.0 0.7 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.0 0.6 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 0.6 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.0 1.5 PID_BCR_5PATHWAY BCR signaling pathway
0.0 7.9 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 0.5 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.0 0.4 SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 0.5 ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.3 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.0 1.2 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.0 0.7 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.6 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.4 PID_FAK_PATHWAY Signaling events mediated by focal adhesion kinase

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 17.9 REACTOME_TRANSPORT_OF_ORGANIC_ANIONS Genes involved in Transport of organic anions
1.2 21.7 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism
1.2 15.4 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.9 5.2 REACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS Genes involved in Recycling of bile acids and salts
0.8 10.3 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM Genes involved in Abacavir transport and metabolism
0.7 20.8 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.4 6.2 REACTOME_COMMON_PATHWAY Genes involved in Common Pathway
0.4 8.6 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.3 4.0 REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.3 3.0 REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN1_SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.2 5.9 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.2 4.0 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2 2.6 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.2 1.8 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.2 7.3 REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS Genes involved in Trafficking of AMPA receptors
0.2 6.7 REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.2 4.4 REACTOME_PEROXISOMAL_LIPID_METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 2.1 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 1.0 REACTOME_OPSINS Genes involved in Opsins
0.1 2.6 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.1 1.4 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 3.9 REACTOME_METABOLISM_OF_STEROID_HORMONES_AND_VITAMINS_A_AND_D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.1 2.9 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.1 2.1 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.1 3.0 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 3.3 REACTOME_COMPLEMENT_CASCADE Genes involved in Complement cascade
0.1 1.6 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 2.6 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.1 4.3 REACTOME_IL1_SIGNALING Genes involved in Interleukin-1 signaling
0.1 3.8 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 4.7 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 1.4 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.1 1.1 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 1.0 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 3.9 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 2.2 REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING Genes involved in Sema4D in semaphorin signaling
0.1 2.6 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 1.1 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 1.5 REACTOME_ENOS_ACTIVATION_AND_REGULATION Genes involved in eNOS activation and regulation
0.0 3.9 REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.7 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 1.7 REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 2.8 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 1.6 REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 3.1 REACTOME_POTASSIUM_CHANNELS Genes involved in Potassium Channels
0.0 0.9 REACTOME_ACTIVATED_POINT_MUTANTS_OF_FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 2.1 REACTOME_AMYLOIDS Genes involved in Amyloids
0.0 1.0 REACTOME_LIGAND_GATED_ION_CHANNEL_TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 2.2 REACTOME_NGF_SIGNALLING_VIA_TRKA_FROM_THE_PLASMA_MEMBRANE Genes involved in NGF signalling via TRKA from the plasma membrane
0.0 0.8 REACTOME_INTEGRIN_ALPHAIIB_BETA3_SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.0 0.5 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.6 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.0 1.4 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.6 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 2.6 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.3 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.4 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.1 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.1 REACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.3 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis