Motif ID: Zbtb4

Z-value: 1.255


Transcription factors associated with Zbtb4:

Gene SymbolEntrez IDGene Name
Zbtb4 ENSMUSG00000018750.8 Zbtb4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zbtb4mm10_v2_chr11_+_69765899_697659250.222.1e-01Click!


Activity profile for motif Zbtb4.

activity profile for motif Zbtb4


Sorted Z-values histogram for motif Zbtb4

Sorted Z-values for motif Zbtb4



Network of associatons between targets according to the STRING database.



First level regulatory network of Zbtb4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_90695706 11.428 ENSMUST00000069960.5
ENSMUST00000117167.1
S100a9

S100 calcium binding protein A9 (calgranulin B)

chr2_-_29869785 8.851 ENSMUST00000047607.1
2600006K01Rik
RIKEN cDNA 2600006K01 gene
chr7_-_141016892 8.593 ENSMUST00000081924.3
Ifitm6
interferon induced transmembrane protein 6
chr11_-_102107822 7.365 ENSMUST00000177304.1
ENSMUST00000017455.8
Pyy

peptide YY

chr11_-_3504766 7.218 ENSMUST00000044507.5
Inpp5j
inositol polyphosphate 5-phosphatase J
chrX_-_93832106 7.064 ENSMUST00000045748.6
Pdk3
pyruvate dehydrogenase kinase, isoenzyme 3
chr10_-_62340514 6.493 ENSMUST00000099691.4
Hk1
hexokinase 1
chrX_+_73639414 6.196 ENSMUST00000019701.8
Dusp9
dual specificity phosphatase 9
chr7_+_142501605 5.794 ENSMUST00000128294.1
ENSMUST00000146804.1
ENSMUST00000105942.1
ENSMUST00000105947.1
ENSMUST00000105943.1
ENSMUST00000105941.1
ENSMUST00000105946.1
ENSMUST00000105948.1
ENSMUST00000105945.1
ENSMUST00000105944.1
Tnnt3









troponin T3, skeletal, fast









chr12_+_102554966 5.741 ENSMUST00000021610.5
Chga
chromogranin A
chr9_-_108190352 5.610 ENSMUST00000035208.7
Bsn
bassoon
chr2_-_170427828 5.407 ENSMUST00000013667.2
ENSMUST00000109152.2
ENSMUST00000068137.4
Bcas1


breast carcinoma amplified sequence 1


chr8_+_83955507 5.338 ENSMUST00000005607.8
Asf1b
ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
chr2_+_25423234 5.277 ENSMUST00000134259.1
ENSMUST00000100320.4
Fut7

fucosyltransferase 7

chr5_-_122050102 5.154 ENSMUST00000154139.1
Cux2
cut-like homeobox 2
chr11_-_116076986 5.088 ENSMUST00000153408.1
Unc13d
unc-13 homolog D (C. elegans)
chr4_-_156255327 4.916 ENSMUST00000179919.1
Samd11
sterile alpha motif domain containing 11
chr6_-_126939524 4.882 ENSMUST00000144954.1
ENSMUST00000112221.1
ENSMUST00000112220.1
Rad51ap1


RAD51 associated protein 1


chr2_+_29869484 4.344 ENSMUST00000047521.6
ENSMUST00000134152.1
Cercam

cerebral endothelial cell adhesion molecule

chr8_-_105637403 4.318 ENSMUST00000182046.1
Gm5914
predicted gene 5914
chr15_+_74563738 4.024 ENSMUST00000170845.1
Bai1
brain-specific angiogenesis inhibitor 1
chr16_-_23127702 4.022 ENSMUST00000115338.1
ENSMUST00000115337.1
ENSMUST00000023598.8
Rfc4


replication factor C (activator 1) 4


chr15_+_73723131 3.810 ENSMUST00000165541.1
ENSMUST00000167582.1
Ptp4a3

protein tyrosine phosphatase 4a3

chr17_-_25727364 3.786 ENSMUST00000170070.1
ENSMUST00000048054.7
Chtf18

CTF18, chromosome transmission fidelity factor 18

chr7_-_126704179 3.717 ENSMUST00000106364.1
Coro1a
coronin, actin binding protein 1A
chr14_+_31134853 3.673 ENSMUST00000090212.4
Nt5dc2
5'-nucleotidase domain containing 2
chr17_-_48409729 3.667 ENSMUST00000160319.1
ENSMUST00000159535.1
ENSMUST00000078800.6
ENSMUST00000046719.7
ENSMUST00000162460.1
Nfya




nuclear transcription factor-Y alpha




chr9_+_59680144 3.588 ENSMUST00000123914.1
Gramd2
GRAM domain containing 2
chr8_-_64693027 3.545 ENSMUST00000048967.7
Cpe
carboxypeptidase E
chr8_+_70501116 3.538 ENSMUST00000127983.1
Crlf1
cytokine receptor-like factor 1
chr11_-_116077562 3.512 ENSMUST00000174822.1
Unc13d
unc-13 homolog D (C. elegans)
chr5_+_143548700 3.472 ENSMUST00000169329.1
ENSMUST00000067145.5
ENSMUST00000119488.1
ENSMUST00000118121.1
Fam220a

Fam220a

family with sequence similarity 220, member A

family with sequence similarity 220, member A

chr17_+_28801090 3.456 ENSMUST00000004985.9
Brpf3
bromodomain and PHD finger containing, 3
chr10_-_116473875 3.339 ENSMUST00000068233.4
Kcnmb4
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr2_-_84822546 3.264 ENSMUST00000028471.5
Smtnl1
smoothelin-like 1
chr9_+_75071579 3.212 ENSMUST00000136731.1
Myo5a
myosin VA
chr17_-_25942821 3.191 ENSMUST00000148382.1
ENSMUST00000145745.1
Pigq

phosphatidylinositol glycan anchor biosynthesis, class Q

chr9_+_75071386 3.153 ENSMUST00000155282.2
Myo5a
myosin VA
chr6_+_127887582 3.142 ENSMUST00000032501.4
Tspan11
tetraspanin 11
chr6_-_57825055 3.115 ENSMUST00000127485.1
Vopp1
vesicular, overexpressed in cancer, prosurvival protein 1
chrX_-_133898399 3.058 ENSMUST00000087557.5
Tspan6
tetraspanin 6
chr7_-_25005895 3.049 ENSMUST00000102858.3
ENSMUST00000080882.6
Atp1a3

ATPase, Na+/K+ transporting, alpha 3 polypeptide

chr2_+_154200371 3.029 ENSMUST00000028987.6
Bpifb1
BPI fold containing family B, member 1
chr11_-_116077606 3.012 ENSMUST00000106450.1
Unc13d
unc-13 homolog D (C. elegans)
chr9_+_96196246 2.945 ENSMUST00000165120.2
ENSMUST00000034982.9
Tfdp2

transcription factor Dp 2

chr6_-_57825144 2.936 ENSMUST00000114297.2
Vopp1
vesicular, overexpressed in cancer, prosurvival protein 1
chr10_+_100015817 2.921 ENSMUST00000130190.1
ENSMUST00000020129.7
Kitl

kit ligand

chr10_+_128225830 2.881 ENSMUST00000026455.7
Mip
major intrinsic protein of eye lens fiber
chr7_+_126766397 2.837 ENSMUST00000032944.7
Gdpd3
glycerophosphodiester phosphodiesterase domain containing 3
chr9_+_106203108 2.759 ENSMUST00000024047.5
Twf2
twinfilin, actin-binding protein, homolog 2 (Drosophila)
chrX_-_133898292 2.745 ENSMUST00000176718.1
ENSMUST00000176641.1
Tspan6

tetraspanin 6

chr9_+_108991902 2.730 ENSMUST00000147989.1
ENSMUST00000051873.8
Pfkfb4

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4

chr3_-_152340350 2.709 ENSMUST00000073089.6
ENSMUST00000068243.6
Fam73a

family with sequence similarity 73, member A

chr7_-_126704522 2.680 ENSMUST00000135087.1
Coro1a
coronin, actin binding protein 1A
chrX_-_111463149 2.606 ENSMUST00000096348.3
ENSMUST00000113428.2
Rps6ka6

ribosomal protein S6 kinase polypeptide 6

chr11_-_69895523 2.582 ENSMUST00000001631.6
Acap1
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
chr13_+_35741313 2.532 ENSMUST00000163595.2
Cdyl
chromodomain protein, Y chromosome-like
chr11_+_50357759 2.455 ENSMUST00000052596.2
Cby3
chibby homolog 3 (Drosophila)
chr8_+_39005827 2.394 ENSMUST00000167992.1
Tusc3
tumor suppressor candidate 3
chr8_+_39005880 2.379 ENSMUST00000169034.1
Tusc3
tumor suppressor candidate 3
chr17_+_6007580 2.371 ENSMUST00000115784.1
ENSMUST00000115785.1
Synj2

synaptojanin 2

chr8_+_85299632 2.363 ENSMUST00000034132.5
ENSMUST00000170141.1
Orc6

origin recognition complex, subunit 6

chr10_+_45335751 2.304 ENSMUST00000095715.3
Bves
blood vessel epicardial substance
chr11_-_74590065 2.264 ENSMUST00000145524.1
ENSMUST00000047488.7
Rap1gap2

RAP1 GTPase activating protein 2

chr9_+_69454066 2.232 ENSMUST00000134907.1
Anxa2
annexin A2
chr6_+_112459501 2.226 ENSMUST00000075477.6
Cav3
caveolin 3
chr7_+_26061495 2.159 ENSMUST00000005669.7
Cyp2b13
cytochrome P450, family 2, subfamily b, polypeptide 13
chr1_-_134079114 2.143 ENSMUST00000020692.6
Btg2
B cell translocation gene 2, anti-proliferative
chrX_+_153139941 2.130 ENSMUST00000039720.4
ENSMUST00000144175.2
Rragb

Ras-related GTP binding B

chr4_-_129440800 2.128 ENSMUST00000053042.5
ENSMUST00000106046.1
Zbtb8b

zinc finger and BTB domain containing 8b

chr8_-_105637350 2.120 ENSMUST00000182863.1
Gm5914
predicted gene 5914
chr5_-_117319242 2.083 ENSMUST00000100834.1
Gm10399
predicted gene 10399
chr1_+_171388954 2.057 ENSMUST00000056449.8
Arhgap30
Rho GTPase activating protein 30
chr9_+_119052770 1.991 ENSMUST00000051386.6
ENSMUST00000074734.6
Vill

villin-like

chr8_-_122678653 1.967 ENSMUST00000134045.1
Cbfa2t3
core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)
chr2_+_156840966 1.967 ENSMUST00000109564.1
Tgif2
TGFB-induced factor homeobox 2
chr5_+_110286306 1.966 ENSMUST00000007296.5
ENSMUST00000112482.1
Pole

polymerase (DNA directed), epsilon

chr16_+_30008657 1.957 ENSMUST00000181485.1
4632428C04Rik
RIKEN cDNA 4632428C04 gene
chr7_-_24545994 1.950 ENSMUST00000011776.6
Pinlyp
phospholipase A2 inhibitor and LY6/PLAUR domain containing
chr1_-_136234113 1.940 ENSMUST00000120339.1
ENSMUST00000048668.8
5730559C18Rik

RIKEN cDNA 5730559C18 gene

chr2_-_73775341 1.936 ENSMUST00000112024.3
ENSMUST00000166199.1
ENSMUST00000180045.1
Chn1


chimerin (chimaerin) 1


chr6_+_83237375 1.925 ENSMUST00000039212.7
ENSMUST00000113899.1
Slc4a5

solute carrier family 4, sodium bicarbonate cotransporter, member 5

chr3_-_57847478 1.916 ENSMUST00000120289.1
ENSMUST00000066882.8
Pfn2

profilin 2

chr8_+_106510853 1.913 ENSMUST00000080797.6
Cdh3
cadherin 3
chr5_+_149678224 1.902 ENSMUST00000100404.3
B3galtl
beta 1,3-galactosyltransferase-like
chr9_-_106096776 1.889 ENSMUST00000121963.1
Col6a4
collagen, type VI, alpha 4
chr6_+_47244359 1.883 ENSMUST00000060839.6
Cntnap2
contactin associated protein-like 2
chr9_-_8042785 1.862 ENSMUST00000065291.1
9230110C19Rik
RIKEN cDNA 9230110C19 gene
chr3_-_109027600 1.850 ENSMUST00000171143.1
Fam102b
family with sequence similarity 102, member B
chr19_+_7417586 1.833 ENSMUST00000159348.1
2700081O15Rik
RIKEN cDNA 2700081O15 gene
chr10_-_60219260 1.795 ENSMUST00000135158.2
Chst3
carbohydrate (chondroitin 6/keratan) sulfotransferase 3
chr11_-_120990871 1.792 ENSMUST00000154483.1
Csnk1d
casein kinase 1, delta
chr9_+_106281061 1.736 ENSMUST00000072206.6
Poc1a
POC1 centriolar protein homolog A (Chlamydomonas)
chr9_+_75071148 1.728 ENSMUST00000123128.1
Myo5a
myosin VA
chr4_+_130360132 1.727 ENSMUST00000105994.3
Snrnp40
small nuclear ribonucleoprotein 40 (U5)
chr11_-_62789445 1.720 ENSMUST00000054654.6
Zfp286
zinc finger protein 286
chr16_+_11984581 1.703 ENSMUST00000170672.2
ENSMUST00000023138.7
Shisa9

shisa homolog 9 (Xenopus laevis)

chr19_+_45047557 1.702 ENSMUST00000062213.5
ENSMUST00000111954.4
ENSMUST00000084493.6
Sfxn3


sideroflexin 3


chr4_+_12906838 1.683 ENSMUST00000143186.1
ENSMUST00000183345.1
Triqk

triple QxxK/R motif containing

chr2_+_32587057 1.656 ENSMUST00000102818.4
St6galnac4
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
chr11_-_62789402 1.621 ENSMUST00000108705.1
Zfp286
zinc finger protein 286
chr6_-_128355826 1.616 ENSMUST00000001562.6
Tulp3
tubby-like protein 3
chr4_-_138757578 1.594 ENSMUST00000030526.6
Pla2g2f
phospholipase A2, group IIF
chr19_-_50678642 1.563 ENSMUST00000072685.6
ENSMUST00000164039.2
Sorcs1

VPS10 domain receptor protein SORCS 1

chr14_-_34201604 1.471 ENSMUST00000096019.2
Gprin2
G protein regulated inducer of neurite outgrowth 2
chr8_+_95081187 1.471 ENSMUST00000034239.7
Katnb1
katanin p80 (WD40-containing) subunit B 1
chr18_-_13972617 1.465 ENSMUST00000025288.7
Zfp521
zinc finger protein 521
chr8_-_13562397 1.458 ENSMUST00000151400.2
ENSMUST00000134023.1
1700029H14Rik

RIKEN cDNA 1700029H14 gene

chr11_-_69837781 1.454 ENSMUST00000108634.2
Nlgn2
neuroligin 2
chr14_+_75016027 1.438 ENSMUST00000036072.7
5031414D18Rik
RIKEN cDNA 5031414D18 gene
chr4_+_156109971 1.429 ENSMUST00000072554.6
ENSMUST00000169550.1
ENSMUST00000105576.1
9430015G10Rik


RIKEN cDNA 9430015G10 gene


chr2_-_9890026 1.419 ENSMUST00000130615.1
Gata3
GATA binding protein 3
chr1_-_171234290 1.413 ENSMUST00000079957.6
Fcer1g
Fc receptor, IgE, high affinity I, gamma polypeptide
chrX_+_164373363 1.392 ENSMUST00000033751.7
Figf
c-fos induced growth factor
chr2_+_30416096 1.367 ENSMUST00000113601.3
ENSMUST00000113603.3
Ppp2r4

protein phosphatase 2A, regulatory subunit B (PR 53)

chr2_-_30903255 1.363 ENSMUST00000102852.3
Ptges
prostaglandin E synthase
chr10_-_81014902 1.362 ENSMUST00000126317.1
ENSMUST00000092285.3
ENSMUST00000117805.1
Gng7


guanine nucleotide binding protein (G protein), gamma 7


chr7_-_35396708 1.359 ENSMUST00000154597.1
ENSMUST00000032704.5
C230052I12Rik

RIKEN cDNA C230052I12 gene

chr9_-_121495678 1.346 ENSMUST00000035120.4
Cck
cholecystokinin
chr9_-_37255730 1.334 ENSMUST00000115068.2
Slc37a2
solute carrier family 37 (glycerol-3-phosphate transporter), member 2
chr18_+_11657349 1.319 ENSMUST00000047322.6
Rbbp8
retinoblastoma binding protein 8
chr2_+_30416031 1.306 ENSMUST00000042055.3
Ppp2r4
protein phosphatase 2A, regulatory subunit B (PR 53)
chr16_+_96235801 1.269 ENSMUST00000113800.2
B3galt5
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5
chr2_-_30415509 1.267 ENSMUST00000134120.1
ENSMUST00000102854.3
Crat

carnitine acetyltransferase

chr8_-_102865853 1.225 ENSMUST00000076373.6
Gm8730
predicted pseudogene 8730
chr7_-_125491397 1.222 ENSMUST00000138616.1
Nsmce1
non-SMC element 1 homolog (S. cerevisiae)
chr15_-_85821733 1.213 ENSMUST00000064370.4
Pkdrej
polycystic kidney disease (polycystin) and REJ (sperm receptor for egg jelly homolog, sea urchin)
chr13_-_55513427 1.206 ENSMUST00000069929.6
ENSMUST00000069968.6
ENSMUST00000131306.1
ENSMUST00000046246.6
Pdlim7



PDZ and LIM domain 7



chr12_+_17924294 1.167 ENSMUST00000169657.1
B430203G13Rik
RIKEN cDNA B430203G13 gene
chr1_+_34678176 1.166 ENSMUST00000159747.2
Arhgef4
Rho guanine nucleotide exchange factor (GEF) 4
chr4_+_119195353 1.166 ENSMUST00000106345.2
Ccdc23
coiled-coil domain containing 23
chr7_+_27553244 1.164 ENSMUST00000067386.7
2310022A10Rik
RIKEN cDNA 2310022A10 gene
chr18_+_42511496 1.155 ENSMUST00000025375.7
Tcerg1
transcription elongation regulator 1 (CA150)
chr3_-_69598822 1.141 ENSMUST00000061826.1
B3galnt1
UDP-GalNAc:betaGlcNAc beta 1,3-galactosaminyltransferase, polypeptide 1
chr1_-_152386589 1.096 ENSMUST00000162371.1
Tsen15
tRNA splicing endonuclease 15 homolog (S. cerevisiae)
chr19_-_50678485 1.086 ENSMUST00000111756.3
Sorcs1
VPS10 domain receptor protein SORCS 1
chr2_+_124610573 1.084 ENSMUST00000103239.3
ENSMUST00000103240.2
Sema6d

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D

chr17_-_29264115 1.057 ENSMUST00000024802.8
Ppil1
peptidylprolyl isomerase (cyclophilin)-like 1
chr7_+_35397046 1.046 ENSMUST00000079414.5
Cep89
centrosomal protein 89
chr9_+_37489281 1.044 ENSMUST00000048604.6
Msantd2
Myb/SANT-like DNA-binding domain containing 2
chr2_+_130406478 1.042 ENSMUST00000055421.4
Tmem239
transmembrane 239
chr2_-_33131645 1.035 ENSMUST00000133135.1
Garnl3
GTPase activating RANGAP domain-like 3
chr8_-_77724426 1.028 ENSMUST00000034029.7
Ednra
endothelin receptor type A
chr1_-_36939521 1.025 ENSMUST00000027290.5
Tmem131
transmembrane protein 131
chr2_-_30415767 0.981 ENSMUST00000102855.1
ENSMUST00000028207.6
Crat

carnitine acetyltransferase

chr2_-_84670659 0.978 ENSMUST00000102646.1
ENSMUST00000102647.3
2700094K13Rik

RIKEN cDNA 2700094K13 gene

chr6_-_49264014 0.977 ENSMUST00000031841.7
Tra2a
transformer 2 alpha homolog (Drosophila)
chr4_+_6365650 0.959 ENSMUST00000029912.4
ENSMUST00000103008.5
ENSMUST00000175769.1
ENSMUST00000108374.1
ENSMUST00000140830.1
Sdcbp




syndecan binding protein




chr5_+_117319292 0.951 ENSMUST00000086464.4
Vsig10
V-set and immunoglobulin domain containing 10
chr13_-_93144557 0.948 ENSMUST00000062122.3
Cmya5
cardiomyopathy associated 5
chr1_-_152386675 0.937 ENSMUST00000015124.8
Tsen15
tRNA splicing endonuclease 15 homolog (S. cerevisiae)
chr6_+_41684414 0.924 ENSMUST00000031900.5
1700034O15Rik
RIKEN cDNA 1700034O15 gene
chr7_-_142372210 0.921 ENSMUST00000084412.5
Ifitm10
interferon induced transmembrane protein 10
chr11_-_120991039 0.915 ENSMUST00000070575.7
Csnk1d
casein kinase 1, delta
chr11_-_119111400 0.897 ENSMUST00000156576.1
Gm11754
predicted gene 11754
chr3_-_83841767 0.877 ENSMUST00000029623.9
Tlr2
toll-like receptor 2
chr11_-_69579320 0.871 ENSMUST00000048139.5
Wrap53
WD repeat containing, antisense to Trp53
chrX_+_41401304 0.856 ENSMUST00000076349.5
Gria3
glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr14_+_120911177 0.853 ENSMUST00000032898.7
Ipo5
importin 5
chr9_-_107635330 0.852 ENSMUST00000055704.6
Gnai2
guanine nucleotide binding protein (G protein), alpha inhibiting 2
chr9_-_21287953 0.848 ENSMUST00000184326.1
ENSMUST00000038671.3
Kri1

KRI1 homolog (S. cerevisiae)

chr14_+_63436394 0.807 ENSMUST00000121288.1
Fam167a
family with sequence similarity 167, member A
chr19_+_4081565 0.805 ENSMUST00000159593.1
Cabp2
calcium binding protein 2
chr9_-_70657121 0.792 ENSMUST00000049031.5
Fam63b
family with sequence similarity 63, member B
chr15_+_100761741 0.788 ENSMUST00000023776.6
Slc4a8
solute carrier family 4 (anion exchanger), member 8
chr2_+_124610278 0.782 ENSMUST00000051419.8
ENSMUST00000077847.5
ENSMUST00000078621.5
ENSMUST00000076335.5
Sema6d



sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D



chr14_-_30626196 0.774 ENSMUST00000112210.3
ENSMUST00000112211.2
ENSMUST00000112208.1
Prkcd


protein kinase C, delta


chr5_+_147957310 0.763 ENSMUST00000085558.4
ENSMUST00000129092.1
Mtus2

microtubule associated tumor suppressor candidate 2

chr7_-_27553138 0.761 ENSMUST00000127240.1
ENSMUST00000117095.1
ENSMUST00000117611.1
Pld3


phospholipase D family, member 3


chr2_-_26516620 0.760 ENSMUST00000132820.1
Notch1
notch 1
chr11_-_3527916 0.754 ENSMUST00000020718.4
Smtn
smoothelin
chr6_-_38876163 0.712 ENSMUST00000161779.1
Hipk2
homeodomain interacting protein kinase 2
chr3_+_138143799 0.711 ENSMUST00000159622.1
Trmt10a
tRNA methyltransferase 10A
chr14_+_31001383 0.706 ENSMUST00000168584.1
Glt8d1
glycosyltransferase 8 domain containing 1
chr4_+_123105146 0.692 ENSMUST00000002457.1
Bmp8b
bone morphogenetic protein 8b
chrX_+_20617503 0.690 ENSMUST00000115375.1
ENSMUST00000115374.1
ENSMUST00000084383.3
Rbm10


RNA binding motif protein 10


chr15_-_58823530 0.684 ENSMUST00000072113.5
Tmem65
transmembrane protein 65
chrX_+_6577259 0.679 ENSMUST00000089520.2
Shroom4
shroom family member 4
chr3_+_65528457 0.678 ENSMUST00000130705.1
Tiparp
TCDD-inducible poly(ADP-ribose) polymerase
chr4_+_129105532 0.677 ENSMUST00000106064.3
ENSMUST00000030575.8
ENSMUST00000030577.4
Tmem54


transmembrane protein 54


chr4_-_6454262 0.660 ENSMUST00000029910.5
Nsmaf
neutral sphingomyelinase (N-SMase) activation associated factor
chr4_+_125066672 0.655 ENSMUST00000052183.6
Snip1
Smad nuclear interacting protein 1
chr7_+_16175085 0.637 ENSMUST00000176342.1
ENSMUST00000177540.1
Meis3

Meis homeobox 3

chr9_-_78378725 0.611 ENSMUST00000034900.7
Ooep
oocyte expressed protein
chr1_-_175692624 0.607 ENSMUST00000027809.7
Opn3
opsin 3
chr18_-_77713978 0.586 ENSMUST00000074653.4
8030462N17Rik
RIKEN cDNA 8030462N17 gene
chr4_+_59805829 0.572 ENSMUST00000030080.6
Snx30
sorting nexin family member 30
chr11_-_50292302 0.570 ENSMUST00000059458.4
Maml1
mastermind like 1 (Drosophila)
chr14_+_31001414 0.567 ENSMUST00000022476.7
Glt8d1
glycosyltransferase 8 domain containing 1
chr7_-_142372342 0.564 ENSMUST00000059223.8
Ifitm10
interferon induced transmembrane protein 10
chr18_+_52767994 0.559 ENSMUST00000025413.7
ENSMUST00000163742.2
ENSMUST00000178011.1
Sncaip


synuclein, alpha interacting protein (synphilin)


chr3_+_152395444 0.554 ENSMUST00000106103.1
Zzz3
zinc finger, ZZ domain containing 3
chr7_+_16175275 0.549 ENSMUST00000176506.1
ENSMUST00000002495.11
Meis3

Meis homeobox 3

chr11_+_75651504 0.483 ENSMUST00000069057.6
Myo1c
myosin IC
chr9_-_37255403 0.478 ENSMUST00000161114.1
Slc37a2
solute carrier family 37 (glycerol-3-phosphate transporter), member 2
chr7_-_132852606 0.458 ENSMUST00000120425.1
Mettl10
methyltransferase like 10
chr15_-_101680281 0.449 ENSMUST00000023786.5
Krt6b
keratin 6B
chr19_-_40612160 0.442 ENSMUST00000132452.1
ENSMUST00000135795.1
ENSMUST00000025981.8
Tctn3


tectonic family member 3


chr19_+_41482632 0.441 ENSMUST00000067795.5
Lcor
ligand dependent nuclear receptor corepressor
chr13_+_85189433 0.433 ENSMUST00000165077.1
ENSMUST00000164127.1
ENSMUST00000163600.1
Ccnh


cyclin H



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.8 11.4 GO:0070488 neutrophil aggregation(GO:0070488)
2.0 8.1 GO:0051643 endoplasmic reticulum localization(GO:0051643)
1.9 5.7 GO:1901079 positive regulation of relaxation of muscle(GO:1901079)
1.9 5.6 GO:0098928 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
1.8 7.1 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
1.5 11.6 GO:0061789 dense core granule priming(GO:0061789)
1.1 6.4 GO:0032796 uropod organization(GO:0032796)
0.9 7.8 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.7 2.2 GO:1905602 regulation of low-density lipoprotein particle receptor binding(GO:1905595) positive regulation of receptor-mediated endocytosis involved in cholesterol transport(GO:1905602)
0.7 4.3 GO:0033026 negative regulation of mast cell apoptotic process(GO:0033026)
0.7 2.0 GO:0045004 DNA replication proofreading(GO:0045004)
0.6 5.8 GO:0039532 negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway(GO:0039532)
0.6 1.8 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.5 6.5 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.5 8.7 GO:0032096 negative regulation of response to food(GO:0032096)
0.5 3.5 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.5 2.5 GO:1905424 regulation of Wnt-mediated midbrain dopaminergic neuron differentiation(GO:1905424) positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation(GO:1905426)
0.5 1.9 GO:0051794 regulation of timing of catagen(GO:0051794)
0.5 1.4 GO:0072204 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204) negative regulation of epithelial tube formation(GO:1905277)
0.4 1.7 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.4 2.9 GO:0015722 canalicular bile acid transport(GO:0015722)
0.4 4.4 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.4 1.9 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.4 2.3 GO:0060931 sinoatrial node cell development(GO:0060931)
0.4 1.9 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.4 2.2 GO:1904180 negative regulation of membrane depolarization(GO:1904180)
0.4 1.5 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.4 3.5 GO:2000173 negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.3 2.8 GO:0032532 regulation of microvillus length(GO:0032532)
0.3 7.2 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.3 1.0 GO:0086100 endothelin receptor signaling pathway(GO:0086100)
0.3 3.0 GO:0034144 negative regulation of toll-like receptor 4 signaling pathway(GO:0034144)
0.3 1.3 GO:0003162 atrioventricular node development(GO:0003162)
0.3 1.3 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.3 1.6 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.3 2.2 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.3 3.8 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.3 3.4 GO:0005513 detection of calcium ion(GO:0005513)
0.3 3.0 GO:0036376 sodium ion export from cell(GO:0036376)
0.3 2.7 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.3 0.9 GO:0052572 positive regulation of interleukin-18 production(GO:0032741) response to immune response of other organism involved in symbiotic interaction(GO:0052564) response to host immune response(GO:0052572) detection of bacterial lipopeptide(GO:0070340) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.3 1.5 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.3 1.7 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.3 4.9 GO:0036297 interstrand cross-link repair(GO:0036297)
0.3 0.8 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.2 5.2 GO:0007614 short-term memory(GO:0007614)
0.2 2.1 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.2 6.2 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.2 2.0 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.2 1.0 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.2 0.9 GO:0070885 negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.2 1.8 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.2 1.3 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.2 3.7 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.2 0.9 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.2 2.6 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.2 5.3 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 1.9 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.1 2.0 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.1 1.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.1 1.4 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 2.1 GO:0060213 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.1 2.4 GO:0051782 negative regulation of cell division(GO:0051782)
0.1 1.9 GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
0.1 3.3 GO:0014823 response to activity(GO:0014823)
0.1 2.4 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 5.8 GO:0003009 skeletal muscle contraction(GO:0003009)
0.1 0.3 GO:0015810 aspartate transport(GO:0015810)
0.1 0.4 GO:0032289 central nervous system myelin formation(GO:0032289)
0.1 1.9 GO:0043086 negative regulation of catalytic activity(GO:0043086)
0.1 0.5 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 0.4 GO:0044861 protein transport into plasma membrane raft(GO:0044861) vascular endothelial cell proliferation(GO:0101023) regulation of vascular endothelial cell proliferation(GO:1905562)
0.1 0.3 GO:0040030 regulation of molecular function, epigenetic(GO:0040030)
0.1 2.0 GO:0038092 nodal signaling pathway(GO:0038092)
0.1 1.9 GO:0070208 protein heterotrimerization(GO:0070208)
0.1 3.2 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.1 0.7 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.1 0.1 GO:0010636 positive regulation of mitochondrial fusion(GO:0010636)
0.1 0.9 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.1 0.6 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 1.2 GO:0060046 regulation of acrosome reaction(GO:0060046)
0.1 0.2 GO:0015828 tyrosine transport(GO:0015828)
0.0 1.4 GO:0001516 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.0 1.3 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 1.6 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.0 0.4 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.7 GO:0002024 diet induced thermogenesis(GO:0002024)
0.0 3.5 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 2.0 GO:0051693 actin filament capping(GO:0051693)
0.0 2.3 GO:2000648 positive regulation of stem cell proliferation(GO:2000648)
0.0 1.7 GO:0055072 iron ion homeostasis(GO:0055072)
0.0 0.2 GO:0045583 regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)
0.0 0.1 GO:2000556 regulation of T-helper 1 cell cytokine production(GO:2000554) positive regulation of T-helper 1 cell cytokine production(GO:2000556)
0.0 0.7 GO:0008209 androgen metabolic process(GO:0008209)
0.0 0.2 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.0 0.4 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 1.3 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.1 GO:0070535 histone H2A K63-linked ubiquitination(GO:0070535)
0.0 1.1 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 2.2 GO:0016573 histone acetylation(GO:0016573)
0.0 0.7 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.0 0.1 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 0.3 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.0 1.5 GO:0009607 response to biotic stimulus(GO:0009607)
0.0 0.9 GO:0001919 regulation of receptor recycling(GO:0001919)
0.0 0.6 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.0 1.2 GO:1903047 mitotic cell cycle(GO:0000278) mitotic nuclear division(GO:0140014) mitotic cell cycle process(GO:1903047)
0.0 0.4 GO:0045109 intermediate filament organization(GO:0045109)
0.0 1.5 GO:0048663 neuron fate commitment(GO:0048663)
0.0 1.2 GO:0046847 filopodium assembly(GO:0046847)
0.0 1.2 GO:2001022 positive regulation of response to DNA damage stimulus(GO:2001022)
0.0 0.9 GO:0071230 cellular response to amino acid stimulus(GO:0071230)
0.0 0.1 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.1 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.0 0.4 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.6 GO:0061245 establishment or maintenance of apical/basal cell polarity(GO:0035088) establishment or maintenance of bipolar cell polarity(GO:0061245)
0.0 0.0 GO:1904742 regulation of telomeric DNA binding(GO:1904742)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 8.1 GO:0042642 actomyosin, myosin complex part(GO:0042642)
1.9 5.6 GO:1990257 piccolo-bassoon transport vesicle(GO:1990257)
1.1 5.7 GO:0042583 chromaffin granule(GO:0042583)
1.1 11.6 GO:0033093 Weibel-Palade body(GO:0033093)
1.0 2.9 GO:0046691 intracellular canaliculus(GO:0046691)
0.9 3.5 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.9 7.8 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.7 2.2 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.6 3.7 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.6 3.5 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.4 2.1 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.4 2.0 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.4 3.0 GO:0044326 dendritic spine neck(GO:0044326)
0.3 5.8 GO:0005861 troponin complex(GO:0005861)
0.3 4.8 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.3 2.4 GO:0005664 nuclear origin of replication recognition complex(GO:0005664)
0.3 6.4 GO:0032426 stereocilium tip(GO:0032426)
0.3 1.3 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.2 3.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.2 6.5 GO:0097228 sperm principal piece(GO:0097228)
0.2 1.7 GO:0032591 dendritic spine membrane(GO:0032591)
0.2 3.5 GO:0031045 dense core granule(GO:0031045)
0.2 2.4 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.2 1.6 GO:0030991 intraciliary transport particle A(GO:0030991)
0.2 1.2 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.1 0.4 GO:0070985 TFIIK complex(GO:0070985)
0.1 1.5 GO:0098936 intrinsic component of postsynaptic membrane(GO:0098936) integral component of postsynaptic membrane(GO:0099055) intrinsic component of synaptic membrane(GO:0099240) integral component of synaptic membrane(GO:0099699)
0.1 0.5 GO:0045160 myosin I complex(GO:0045160)
0.1 0.4 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.1 2.2 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 1.9 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 1.3 GO:0043203 axon hillock(GO:0043203)
0.1 1.4 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 0.4 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1 0.4 GO:0071817 MMXD complex(GO:0071817)
0.1 3.3 GO:0031430 M band(GO:0031430)
0.1 0.3 GO:1990023 mitotic spindle midzone(GO:1990023)
0.1 6.7 GO:0043198 dendritic shaft(GO:0043198)
0.1 2.1 GO:0071011 precatalytic spliceosome(GO:0071011)
0.1 5.7 GO:0030175 filopodium(GO:0030175)
0.0 2.5 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.9 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 4.3 GO:0000922 spindle pole(GO:0000922)
0.0 2.2 GO:0005834 heterotrimeric G-protein complex(GO:0005834) GTPase complex(GO:1905360)
0.0 0.3 GO:0097546 ciliary base(GO:0097546)
0.0 3.4 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.6 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.9 GO:0043034 costamere(GO:0043034)
0.0 2.3 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.2 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 0.7 GO:0016460 myosin II complex(GO:0016460)
0.0 8.1 GO:0000139 Golgi membrane(GO:0000139)
0.0 1.4 GO:0042629 mast cell granule(GO:0042629)
0.0 0.8 GO:0030686 90S preribosome(GO:0030686)
0.0 1.1 GO:0030315 T-tubule(GO:0030315)
0.0 0.7 GO:0014704 intercalated disc(GO:0014704)
0.0 0.8 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 1.2 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.2 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.0 3.0 GO:0031965 nuclear membrane(GO:0031965)
0.0 1.3 GO:0016363 nuclear matrix(GO:0016363)
0.0 1.1 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 1.0 GO:0016605 PML body(GO:0016605)
0.0 1.1 GO:0017053 transcriptional repressor complex(GO:0017053)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 7.2 GO:0052658 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485) inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
1.8 7.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
1.4 11.4 GO:0050786 Toll-like receptor 4 binding(GO:0035662) RAGE receptor binding(GO:0050786)
1.2 3.5 GO:0097677 STAT family protein binding(GO:0097677)
0.9 5.3 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.8 5.8 GO:0031013 troponin C binding(GO:0030172) calcium-dependent ATPase activity(GO:0030899) troponin I binding(GO:0031013)
0.8 4.9 GO:0042731 PH domain binding(GO:0042731)
0.7 2.2 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.7 6.5 GO:0008865 fructokinase activity(GO:0008865)
0.7 7.8 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.6 4.2 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.6 2.2 GO:0004092 carnitine O-acetyltransferase activity(GO:0004092)
0.5 8.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.5 2.9 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.5 1.8 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.4 3.5 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.4 6.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.4 4.8 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.4 8.7 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.4 1.8 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.4 1.4 GO:0019767 IgE receptor activity(GO:0019767)
0.3 1.0 GO:0004962 endothelin receptor activity(GO:0004962)
0.3 1.4 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.3 2.0 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.3 2.7 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.3 6.4 GO:0032036 myosin heavy chain binding(GO:0032036)
0.3 3.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.3 1.9 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.3 3.5 GO:0004185 serine-type carboxypeptidase activity(GO:0004185) cobalt ion binding(GO:0050897)
0.2 2.0 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.2 1.4 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.2 5.6 GO:0001222 transcription corepressor binding(GO:0001222)
0.2 3.0 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.2 2.4 GO:0034595 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439) phosphatidylinositol phosphate 5-phosphatase activity(GO:0034595)
0.2 1.5 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.2 3.3 GO:0005523 tropomyosin binding(GO:0005523)
0.2 0.8 GO:0070976 TIR domain binding(GO:0070976)
0.2 3.7 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.2 2.8 GO:0015250 water channel activity(GO:0015250)
0.2 1.7 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.2 5.7 GO:0004935 adrenergic receptor activity(GO:0004935)
0.2 0.7 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.1 2.4 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 0.9 GO:0071723 lipopeptide binding(GO:0071723)
0.1 0.3 GO:0002046 opsin binding(GO:0002046)
0.1 1.1 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.1 4.7 GO:0003785 actin monomer binding(GO:0003785)
0.1 1.0 GO:0045545 syndecan binding(GO:0045545)
0.1 3.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 1.9 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.8 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 1.3 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.1 3.4 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 2.5 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 3.7 GO:0001221 transcription cofactor binding(GO:0001221)
0.1 0.3 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 0.6 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 1.1 GO:0046790 virion binding(GO:0046790)
0.1 0.9 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907) G-protein coupled neurotransmitter receptor activity(GO:0099528)
0.1 0.9 GO:0070034 telomerase RNA binding(GO:0070034)
0.1 0.2 GO:0005302 L-tyrosine transmembrane transporter activity(GO:0005302)
0.1 0.4 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.1 2.3 GO:0030552 cAMP binding(GO:0030552)
0.0 0.3 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 4.2 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 1.2 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 2.5 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 1.9 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 6.8 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 1.2 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 7.2 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.6 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.7 GO:0097602 cullin family protein binding(GO:0097602)
0.0 5.2 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.7 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 0.5 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 1.1 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.4 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.9 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 5.6 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.0 GO:0051431 corticotropin-releasing hormone receptor 1 binding(GO:0051430) corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.0 0.6 GO:0042605 peptide antigen binding(GO:0042605)
0.0 3.1 GO:0051015 actin filament binding(GO:0051015)
0.0 3.0 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.0 0.8 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 0.2 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.4 GO:0008378 galactosyltransferase activity(GO:0008378)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 11.1 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.1 3.8 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.1 6.2 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.1 1.4 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.1 4.0 PID_ATR_PATHWAY ATR signaling pathway
0.1 7.1 PID_P53_REGULATION_PATHWAY p53 pathway
0.1 0.9 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.1 2.2 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.1 4.8 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.1 6.5 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.1 1.4 PID_ATM_PATHWAY ATM pathway
0.1 1.0 PID_IL5_PATHWAY IL5-mediated signaling events
0.1 1.4 PID_IL27_PATHWAY IL27-mediated signaling events
0.0 1.2 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 2.0 PID_ERBB4_PATHWAY ErbB4 signaling events
0.0 0.8 ST_GA12_PATHWAY G alpha 12 Pathway
0.0 2.5 PID_MTOR_4PATHWAY mTOR signaling pathway
0.0 2.0 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.4 PID_FCER1_PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 1.0 PID_ENDOTHELIN_PATHWAY Endothelins
0.0 1.5 ST_FAS_SIGNALING_PATHWAY Fas Signaling Pathway
0.0 0.6 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 1.2 PID_E2F_PATHWAY E2F transcription factor network
0.0 0.8 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.4 PID_RETINOIC_ACID_PATHWAY Retinoic acid receptors-mediated signaling
0.0 2.2 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.3 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.0 0.7 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 7.1 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.5 11.6 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.4 3.7 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.4 6.0 REACTOME_REPAIR_SYNTHESIS_FOR_GAP_FILLING_BY_DNA_POL_IN_TC_NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.2 2.4 REACTOME_E2F_ENABLED_INHIBITION_OF_PRE_REPLICATION_COMPLEX_FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.2 2.8 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.2 9.7 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.2 5.1 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 0.9 REACTOME_BETA_DEFENSINS Genes involved in Beta defensins
0.1 6.5 REACTOME_GLUCOSE_TRANSPORT Genes involved in Glucose transport
0.1 1.4 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 3.4 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.1 1.4 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 1.8 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 0.6 REACTOME_OPSINS Genes involved in Opsins
0.1 1.7 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 2.3 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.1 0.8 REACTOME_MRNA_CAPPING Genes involved in mRNA Capping
0.1 2.7 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.1 9.7 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 3.0 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.1 0.9 REACTOME_EXTENSION_OF_TELOMERES Genes involved in Extension of Telomeres
0.1 2.2 REACTOME_ADP_SIGNALLING_THROUGH_P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.1 2.6 REACTOME_RECYCLING_PATHWAY_OF_L1 Genes involved in Recycling pathway of L1
0.1 0.9 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 4.8 REACTOME_ASPARAGINE_N_LINKED_GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.0 2.0 REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 1.9 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.0 2.6 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 1.7 REACTOME_MRNA_SPLICING_MINOR_PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.6 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 1.0 REACTOME_PEROXISOMAL_LIPID_METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.8 REACTOME_CA_DEPENDENT_EVENTS Genes involved in Ca-dependent events
0.0 0.4 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 1.3 REACTOME_MEIOTIC_RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.5 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 2.9 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.3 REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 0.9 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 1.0 REACTOME_L1CAM_INTERACTIONS Genes involved in L1CAM interactions