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GSE58827: Dynamics of the Mouse Liver

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Results for Zbtb6

Z-value: 0.60

Motif logo

Transcription factors associated with Zbtb6

Gene Symbol Gene ID Gene Info
ENSMUSG00000066798.3 zinc finger and BTB domain containing 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Zbtb6mm10_v2_chr2_-_37430835_37430919-0.057.6e-01Click!

Activity profile of Zbtb6 motif

Sorted Z-values of Zbtb6 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr16_-_16863975 3.19 ENSMUST00000100136.3
immunoglobulin lambda-like polypeptide 1
chr16_-_16863817 2.99 ENSMUST00000124890.1
immunoglobulin lambda-like polypeptide 1
chr8_-_85365341 2.93 ENSMUST00000121972.1
myosin light chain kinase 3
chr8_-_85365317 2.93 ENSMUST00000034133.7
myosin light chain kinase 3
chr11_-_102897123 2.71 ENSMUST00000067444.3
glial fibrillary acidic protein
chr4_-_87806296 2.53 ENSMUST00000126353.1
ENSMUST00000149357.1
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr11_-_102897146 2.48 ENSMUST00000077902.4
glial fibrillary acidic protein
chr7_-_100855403 2.39 ENSMUST00000156855.1
RELT tumor necrosis factor receptor
chr17_+_36869567 2.31 ENSMUST00000060524.9
tripartite motif-containing 10
chr4_-_87806276 1.99 ENSMUST00000148059.1
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr7_-_141279121 1.89 ENSMUST00000167790.1
ENSMUST00000046156.6
secretin
chr11_-_94474088 1.76 ENSMUST00000107786.1
ENSMUST00000107791.1
ENSMUST00000103166.2
ENSMUST00000107792.1
ENSMUST00000100561.3
ENSMUST00000107793.1
ENSMUST00000107788.1
ENSMUST00000107790.1
ENSMUST00000107789.1
ENSMUST00000107785.1
ENSMUST00000021234.8
calcium channel, voltage-dependent, T type, alpha 1G subunit
chr6_-_60829826 1.66 ENSMUST00000163779.1
synuclein, alpha
chr1_+_134182404 1.57 ENSMUST00000153856.1
ENSMUST00000082060.3
ENSMUST00000133701.1
ENSMUST00000132873.1
chitinase 3-like 1
chr6_+_4755327 1.54 ENSMUST00000176551.1
paternally expressed 10
chrX_-_53240101 1.42 ENSMUST00000074861.2
placental specific protein 1
chr1_+_134182150 1.34 ENSMUST00000156873.1
chitinase 3-like 1
chr17_+_25298389 1.27 ENSMUST00000037453.2
protease, serine, 34
chr11_-_80080928 1.26 ENSMUST00000103233.3
ENSMUST00000061283.8
cytokine receptor-like factor 3
chr4_+_107802277 1.26 ENSMUST00000106733.2
ENSMUST00000030356.3
ENSMUST00000106732.2
ENSMUST00000126573.1
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
chr17_-_45733843 1.18 ENSMUST00000178179.1
RIKEN cDNA 1600014C23 gene
chr3_+_103102604 1.13 ENSMUST00000173206.1
DENN/MADD domain containing 2C
chr4_-_133887765 1.07 ENSMUST00000003741.9
ENSMUST00000105894.4
ribosomal protein S6 kinase polypeptide 1
chr4_+_117835387 1.04 ENSMUST00000169885.1
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr11_-_76027726 1.04 ENSMUST00000021207.6
family with sequence similarity 101, member B
chr15_-_101712891 1.03 ENSMUST00000023709.5
keratin 5
chr4_+_13743424 1.03 ENSMUST00000006761.3
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr7_-_98178254 1.02 ENSMUST00000040971.7
calpain 5
chr6_+_123262107 1.02 ENSMUST00000032240.2
C-type lectin domain family 4, member d
chr13_+_55369732 0.99 ENSMUST00000063771.7
regulator of G-protein signaling 14
chr12_+_111406809 0.98 ENSMUST00000150384.1
RIKEN cDNA A230065H16 gene
chr6_+_113531675 0.95 ENSMUST00000036340.5
ENSMUST00000101051.2
Fanconi anemia, complementation group D2
chr12_-_83951355 0.92 ENSMUST00000181399.1
predicted gene, 26571
chr9_-_61976563 0.86 ENSMUST00000113990.1
progestin and adipoQ receptor family member V
chr7_-_38107490 0.86 ENSMUST00000108023.3
cyclin E1
chr11_-_102946688 0.85 ENSMUST00000057849.5
complement component 1, q subcomponent-like 1
chr7_-_45136231 0.84 ENSMUST00000124300.1
ENSMUST00000085377.5
ribosomal protein L13A
FMS-like tyrosine kinase 3 ligand
chr9_-_21760275 0.83 ENSMUST00000098942.4
SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chrX_+_50841434 0.82 ENSMUST00000114887.2
RIKEN cDNA 2610018G03 gene
chr17_+_25366550 0.79 ENSMUST00000069616.7
tryptase beta 2
chr4_-_156200818 0.78 ENSMUST00000085425.4
ISG15 ubiquitin-like modifier
chr2_-_126618655 0.77 ENSMUST00000028838.4
histidine decarboxylase
chr9_+_22411515 0.77 ENSMUST00000058868.7
RIKEN cDNA 9530077C05 gene
chr2_-_92371039 0.76 ENSMUST00000068586.6
glycosyltransferase-like 1B
chr17_+_28952425 0.75 ENSMUST00000118762.1
ENSMUST00000057174.8
ENSMUST00000122163.1
ENSMUST00000153831.1
potassium channel tetramerisation domain containing 20
chr2_-_92370999 0.75 ENSMUST00000176810.1
ENSMUST00000090582.4
glycosyltransferase-like 1B
chr11_-_12026237 0.75 ENSMUST00000150972.1
growth factor receptor bound protein 10
chr5_-_100562836 0.74 ENSMUST00000097437.2
placenta-specific 8
chr15_+_78913916 0.73 ENSMUST00000089378.4
pyridoxal (pyridoxine, vitamin B6) phosphatase
chr4_+_127169131 0.70 ENSMUST00000046659.7
discs, large (Drosophila) homolog-associated protein 3
chr12_-_8539545 0.69 ENSMUST00000095863.3
ENSMUST00000165657.1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 15
chr7_+_24547150 0.68 ENSMUST00000063249.8
X-ray repair complementing defective repair in Chinese hamster cells 1
chr8_-_10928449 0.66 ENSMUST00000040608.3
RIKEN cDNA 3930402G23 gene
chr2_-_92370968 0.63 ENSMUST00000176774.1
glycosyltransferase-like 1B
chr6_-_91116785 0.62 ENSMUST00000113509.1
ENSMUST00000032179.7
nucleoporin 210
chr14_-_54966570 0.61 ENSMUST00000124930.1
ENSMUST00000134256.1
ENSMUST00000081857.6
ENSMUST00000145322.1
myosin, heavy polypeptide 6, cardiac muscle, alpha
chr7_+_28788955 0.60 ENSMUST00000059857.7
Ras and Rab interactor-like
chr17_-_46153517 0.60 ENSMUST00000171172.1
MAD2L1 binding protein
chr11_+_3488275 0.58 ENSMUST00000064265.6
phospholipase A2, group III
chr8_-_105707933 0.58 ENSMUST00000013299.9
enkurin domain containing 1
chr3_-_95307132 0.57 ENSMUST00000015846.2
annexin A9
chr8_+_75093591 0.57 ENSMUST00000005548.6
heme oxygenase (decycling) 1
chr1_+_167001457 0.57 ENSMUST00000126198.1
family with sequence similarity 78, member B
chr11_-_59035064 0.56 ENSMUST00000138587.1
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
chr19_+_33822908 0.56 ENSMUST00000042061.6
predicted pseudogene 5519
chr4_-_141053660 0.55 ENSMUST00000040222.7
ciliary rootlet coiled-coil, rootletin
chr4_+_124986430 0.55 ENSMUST00000030687.7
R-spondin homolog (Xenopus laevis)
chr10_-_95673451 0.55 ENSMUST00000099328.1
anaphase prompoting complex C subunit 15, pseudogene
chr12_-_10900296 0.54 ENSMUST00000085735.2
phosphoglycerate kinase-1, related sequence-7
chr17_+_34850373 0.53 ENSMUST00000097343.4
ENSMUST00000173357.1
ENSMUST00000173065.1
ENSMUST00000165953.2
negative elongation factor complex member E, Rdbp
chr4_-_141053704 0.52 ENSMUST00000102491.3
ciliary rootlet coiled-coil, rootletin
chr2_-_180334665 0.51 ENSMUST00000015771.2
GATA binding protein 5
chr11_-_71142366 0.51 ENSMUST00000048514.4
NLR family, pyrin domain containing 1A
chr17_-_56300286 0.50 ENSMUST00000097303.1
arrestin domain containing 5
chr8_+_83389846 0.50 ENSMUST00000002259.6
calmegin
chr6_-_114042020 0.50 ENSMUST00000101045.3
ATPase, Ca++ transporting, plasma membrane 2
chr9_+_108826320 0.49 ENSMUST00000024238.5
cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)
chr5_+_47984793 0.47 ENSMUST00000170109.2
ENSMUST00000174421.1
ENSMUST00000173702.1
ENSMUST00000173107.1
slit homolog 2 (Drosophila)
chr8_+_83389878 0.47 ENSMUST00000109831.2
calmegin
chr16_+_18877037 0.47 ENSMUST00000120532.1
ENSMUST00000004222.7
histone cell cycle regulation defective homolog A (S. cerevisiae)
chr1_+_64532790 0.46 ENSMUST00000049932.5
ENSMUST00000087366.4
ENSMUST00000171164.1
cAMP responsive element binding protein 1
chr8_+_85026833 0.44 ENSMUST00000047281.8
RIKEN cDNA 2310036O22 gene
chr15_+_98108465 0.44 ENSMUST00000051226.6
phosphofructokinase, muscle
chr3_+_138742195 0.44 ENSMUST00000029800.2
tetraspanin 5
chr4_-_133967235 0.43 ENSMUST00000123234.1
high mobility group nucleosomal binding domain 2
chr15_+_102990576 0.43 ENSMUST00000001703.6
homeobox C8
chr9_+_66350465 0.41 ENSMUST00000042824.6
hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain (RLD) 1
chr17_+_46650328 0.40 ENSMUST00000043464.7
cullin 7
chr8_-_124021008 0.40 ENSMUST00000093039.5
TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor
chr11_-_72361837 0.39 ENSMUST00000108503.2
tektin 1
chr11_-_61342821 0.38 ENSMUST00000134423.1
ENSMUST00000093029.2
solute carrier family 47, member 2
chr15_-_79687776 0.37 ENSMUST00000023061.5
Josephin domain containing 1
chr5_+_47984571 0.37 ENSMUST00000174313.1
slit homolog 2 (Drosophila)
chr9_+_113930934 0.37 ENSMUST00000084885.5
ENSMUST00000009885.7
upstream binding protein 1
chr4_-_133967296 0.37 ENSMUST00000105893.1
high mobility group nucleosomal binding domain 2
chr15_-_95528702 0.37 ENSMUST00000166170.1
NEL-like 2
chr10_-_40142247 0.36 ENSMUST00000092566.6
solute carrier family 16 (monocarboxylic acid transporters), member 10
chr11_-_72411695 0.36 ENSMUST00000108500.1
ENSMUST00000050226.6
smoothelin-like 2
chr17_+_24038144 0.36 ENSMUST00000059482.5
protease, serine, 27
chr13_+_73317844 0.36 ENSMUST00000085163.3
predicted gene 10263
chr7_-_24435491 0.34 ENSMUST00000080594.6
immunity-related GTPase family, cinema 1
chr1_+_75549581 0.34 ENSMUST00000154101.1
solute carrier family 4 (anion exchanger), member 3
chr3_+_108092789 0.34 ENSMUST00000058669.8
ENSMUST00000145101.1
guanine nucleotide binding protein, alpha transducing 2
chr7_-_45136056 0.34 ENSMUST00000130628.1
FMS-like tyrosine kinase 3 ligand
chr7_-_45136102 0.34 ENSMUST00000125500.1
FMS-like tyrosine kinase 3 ligand
chr4_-_141538434 0.33 ENSMUST00000078886.3
SPEN homolog, transcriptional regulator (Drosophila)
chr10_+_19712587 0.33 ENSMUST00000020185.3
interleukin 20 receptor, alpha
chr19_-_31765027 0.32 ENSMUST00000065067.6
protein kinase, cGMP-dependent, type I
chr15_-_51865448 0.31 ENSMUST00000022925.8
eukaryotic translation initiation factor 3, subunit H
chr17_-_35115428 0.30 ENSMUST00000172854.1
ENSMUST00000062657.4
lymphocyte antigen 6 complex, locus G5B
chr2_+_139493913 0.30 ENSMUST00000110083.1
ENSMUST00000047370.2
serine palmitoyltransferase, long chain base subunit 3
chr9_-_45984816 0.29 ENSMUST00000172450.1
platelet-activating factor acetylhydrolase, isoform 1b, subunit 2
chr6_-_99044414 0.29 ENSMUST00000177507.1
ENSMUST00000123992.1
forkhead box P1
chr2_+_31759932 0.28 ENSMUST00000028190.6
c-abl oncogene 1, non-receptor tyrosine kinase
chr19_+_4192129 0.28 ENSMUST00000046094.4
protein phosphatase 1, catalytic subunit, alpha isoform
chr11_-_83429455 0.28 ENSMUST00000052521.2
growth arrest-specific 2 like 2
chr10_-_75932468 0.27 ENSMUST00000120281.1
ENSMUST00000000924.6
matrix metallopeptidase 11
chr4_+_129189760 0.26 ENSMUST00000106054.2
ENSMUST00000001365.2
tyrosyl-tRNA synthetase
chr8_+_105605220 0.26 ENSMUST00000043531.8
family with sequence similarity 65, member A
chr5_-_120588613 0.26 ENSMUST00000046426.8
two pore channel 1
chr7_+_101818306 0.26 ENSMUST00000008090.9
paired-like homeobox 2a
chr9_-_22135675 0.25 ENSMUST00000165735.1
acid phosphatase 5, tartrate resistant
chr8_-_116978908 0.25 ENSMUST00000070577.5
RIKEN cDNA 1700030J22 gene
chr3_+_108093109 0.25 ENSMUST00000151326.1
guanine nucleotide binding protein, alpha transducing 2
chr11_+_67277124 0.24 ENSMUST00000019625.5
myosin, heavy polypeptide 8, skeletal muscle, perinatal
chr14_-_69707546 0.23 ENSMUST00000118374.1
R3H domain and coiled-coil containing 1
chr1_-_75264195 0.23 ENSMUST00000027404.5
protein tyrosine phosphatase, receptor type, N
chr9_+_107296843 0.23 ENSMUST00000167072.1
cytokine inducible SH2-containing protein
chr3_+_96104498 0.23 ENSMUST00000132980.1
ENSMUST00000138206.1
ENSMUST00000090785.2
ENSMUST00000035519.5
OTU domain containing 7B
chr15_+_39198244 0.22 ENSMUST00000082054.5
ENSMUST00000042917.9
regulating synaptic membrane exocytosis 2
chr3_-_97227364 0.22 ENSMUST00000046521.7
B cell CLL/lymphoma 9
chr5_-_107597533 0.21 ENSMUST00000124140.1
glomulin, FKBP associated protein
chr7_+_3289012 0.21 ENSMUST00000164553.1
myeloid-associated differentiation marker
chr5_-_18360384 0.21 ENSMUST00000074694.5
guanine nucleotide binding protein (G protein), alpha inhibiting 1
chr16_+_58408443 0.21 ENSMUST00000046663.7
discoidin, CUB and LCCL domain containing 2
chr11_+_70026815 0.20 ENSMUST00000135916.2
discs, large homolog 4 (Drosophila)
chr16_+_38562821 0.20 ENSMUST00000163948.1
transmembrane protein 39a
chr4_+_103143052 0.20 ENSMUST00000106855.1
mesoderm induction early response 1 homolog (Xenopus laevis
chr1_-_74588117 0.20 ENSMUST00000066986.6
zinc finger protein 142
chr18_-_42262053 0.20 ENSMUST00000097590.3
leucyl-tRNA synthetase
chr1_-_74587964 0.20 ENSMUST00000027315.7
ENSMUST00000113737.1
zinc finger protein 142
chr4_+_123787857 0.20 ENSMUST00000053202.5
rhomboid, veinlet-like 2 (Drosophila)
chr14_-_69707493 0.20 ENSMUST00000121142.1
R3H domain and coiled-coil containing 1
chr11_-_42182924 0.19 ENSMUST00000020707.5
ENSMUST00000132971.1
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1
chr11_-_17953861 0.18 ENSMUST00000076661.6
Ewing's tumor-associated antigen 1
chr1_-_133131782 0.18 ENSMUST00000180528.1
predicted gene, 26616
chr8_-_70439557 0.18 ENSMUST00000076615.5
CREB regulated transcription coactivator 1
chrX_-_7319186 0.18 ENSMUST00000115746.1
chloride channel 5
chr6_-_112489808 0.18 ENSMUST00000053306.6
oxytocin receptor
chrX_-_7319291 0.18 ENSMUST00000128319.1
chloride channel 5
chr17_+_35135695 0.17 ENSMUST00000174478.1
ENSMUST00000174281.2
ENSMUST00000173550.1
BCL2-associated athanogene 6
chr19_-_46573059 0.17 ENSMUST00000026009.8
ADP-ribosylation factor-like 3
chr2_+_102550012 0.17 ENSMUST00000028612.7
peptidase domain containing associated with muscle regeneration 1
chr15_-_33405976 0.17 ENSMUST00000079057.6
RIKEN cDNA 1700084J12 gene
chr4_-_132796361 0.17 ENSMUST00000045154.5
thymocyte selection associated family member 2
chr9_-_99717259 0.16 ENSMUST00000112882.2
ENSMUST00000131922.1
claudin 18
chr16_+_38562806 0.16 ENSMUST00000171687.1
ENSMUST00000002924.8
transmembrane protein 39a
chr13_-_40733768 0.16 ENSMUST00000110193.2
transcription factor AP-2, alpha
chr3_-_66981279 0.16 ENSMUST00000162098.2
short stature homeobox 2
chr11_+_83409655 0.15 ENSMUST00000175848.1
ENSMUST00000108140.3
RAS-like, family 10, member B
chr2_-_54085542 0.15 ENSMUST00000100089.2
reprimo, TP53 dependent G2 arrest mediator candidate
chr13_-_98637354 0.15 ENSMUST00000050389.4
transmembrane protein 174
chr11_+_3989924 0.15 ENSMUST00000109981.1
galactose-3-O-sulfotransferase 1
chr14_-_54913089 0.14 ENSMUST00000050772.7
solute carrier family 22 (organic cation transporter), member 17
chr5_+_73406076 0.14 ENSMUST00000031040.6
ENSMUST00000065543.6
cell wall biogenesis 43 C-terminal homolog (S. cerevisiae)
chr17_-_17624458 0.14 ENSMUST00000041047.2
leucyl/cystinyl aminopeptidase
chr11_+_114765363 0.13 ENSMUST00000138804.1
ENSMUST00000084368.5
kinesin family member 19A
chr3_-_92687209 0.13 ENSMUST00000029524.3
late cornified envelope 1D
chr14_+_54894133 0.13 ENSMUST00000116476.2
ENSMUST00000022808.7
ENSMUST00000150975.1
poly(A) binding protein, nuclear 1
chr9_+_108479849 0.13 ENSMUST00000065014.4
laminin, beta 2
chr7_-_45136391 0.13 ENSMUST00000146760.1
FMS-like tyrosine kinase 3 ligand
chr10_+_21593151 0.13 ENSMUST00000057341.4
RIKEN cDNA 1700020N01 gene
chr15_+_99126513 0.13 ENSMUST00000063517.4
spermatogenesis associated, serine-rich 2
chr11_+_74770908 0.13 ENSMUST00000128504.1
methyltransferase like 16
chr7_-_84086494 0.13 ENSMUST00000064174.5
RIKEN cDNA 9930013L23 gene
chr18_-_53744509 0.12 ENSMUST00000049811.6
centrosomal protein 120
chr1_-_184732444 0.12 ENSMUST00000174257.1
H2.0-like homeobox
chr7_+_127233227 0.12 ENSMUST00000056232.6
zinc finger protein 553
chr7_-_21427941 0.11 ENSMUST00000177741.1
predicted gene 6882
chr2_-_180104463 0.11 ENSMUST00000056480.3
histamine receptor H3
chr14_+_54894573 0.11 ENSMUST00000141446.1
ENSMUST00000139985.1
ENSMUST00000172557.1
poly(A) binding protein, nuclear 1
chr1_-_184732616 0.11 ENSMUST00000048572.6
H2.0-like homeobox
chr3_-_65958236 0.10 ENSMUST00000029416.7
cyclin L1
chr7_+_127233044 0.10 ENSMUST00000106312.3
zinc finger protein 553
chr10_-_82623190 0.10 ENSMUST00000183363.1
ENSMUST00000079648.5
ENSMUST00000185168.1
RIKEN cDNA 1190007I07 gene
chr1_+_75546258 0.10 ENSMUST00000124341.1
solute carrier family 4 (anion exchanger), member 3
chr8_-_60954726 0.10 ENSMUST00000110302.1
chloride channel 3
chr4_-_127061085 0.09 ENSMUST00000136186.1
ENSMUST00000106099.1
zinc finger, MYM domain containing 1
chrX_-_162159717 0.09 ENSMUST00000087085.3
Nance-Horan syndrome (human)
chr1_+_134560157 0.09 ENSMUST00000047714.7
lysine (K)-specific demethylase 5B
chr8_-_105347885 0.09 ENSMUST00000014922.4
formin homology 2 domain containing 1
chr5_-_72168142 0.09 ENSMUST00000013693.6
COMM domain containing 8
chr12_-_3357012 0.09 ENSMUST00000180719.1
predicted gene, 26520
chr15_+_58141397 0.09 ENSMUST00000067563.7
WDYHV motif containing 1
chr5_+_137553517 0.08 ENSMUST00000136088.1
ENSMUST00000139395.1
ENSMUST00000136565.1
ENSMUST00000149292.1
ENSMUST00000125489.1
actin-like 6B
chr11_+_74770822 0.08 ENSMUST00000141755.1
ENSMUST00000010698.6
methyltransferase like 16
chr19_-_23273893 0.08 ENSMUST00000087556.5
structural maintenance of chromosomes 5
chr14_+_46882854 0.07 ENSMUST00000022386.8
ENSMUST00000100672.3
sterile alpha motif domain containing 4
chr7_-_45370559 0.07 ENSMUST00000003971.7
lin-7 homolog B (C. elegans)
chr13_-_21531032 0.07 ENSMUST00000156674.2
ENSMUST00000110481.2
zinc finger with KRAB and SCAN domains 8

Network of associatons between targets according to the STRING database.

First level regulatory network of Zbtb6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 5.9 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.8 6.8 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.6 1.9 GO:0001698 gastrin-induced gastric acid secretion(GO:0001698) positive regulation of somatostatin secretion(GO:0090274)
0.4 1.8 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.3 1.0 GO:0061536 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.3 1.6 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.3 4.6 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.3 0.8 GO:0050924 corticospinal neuron axon guidance through spinal cord(GO:0021972) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
0.3 1.1 GO:0032053 ciliary basal body organization(GO:0032053)
0.2 1.4 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.2 0.9 GO:0061743 motor learning(GO:0061743)
0.2 1.0 GO:0038094 Fc-gamma receptor signaling pathway(GO:0038094)
0.2 0.6 GO:0034395 regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
0.2 0.7 GO:0042822 pyridoxal phosphate metabolic process(GO:0042822)
0.2 0.7 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.2 0.5 GO:0032916 positive regulation of transforming growth factor beta3 production(GO:0032916)
0.2 0.8 GO:0006548 histamine metabolic process(GO:0001692) histidine catabolic process(GO:0006548)
0.1 1.3 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.1 0.4 GO:0021622 oculomotor nerve morphogenesis(GO:0021622) oculomotor nerve formation(GO:0021623)
0.1 5.4 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 1.1 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.1 1.3 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 2.3 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.1 0.8 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 1.0 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.1 1.0 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 0.5 GO:0048840 otolith development(GO:0048840)
0.1 0.5 GO:0036515 serotonergic neuron axon guidance(GO:0036515)
0.1 0.2 GO:1904245 regulation of polynucleotide adenylyltransferase activity(GO:1904245)
0.1 0.2 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.1 0.4 GO:0061622 glycolytic process through glucose-1-phosphate(GO:0061622)
0.1 0.6 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.1 0.7 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719)
0.1 0.1 GO:0072244 metanephric glomerular epithelium development(GO:0072244)
0.1 0.2 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.1 0.6 GO:0019372 lipoxygenase pathway(GO:0019372)
0.1 0.6 GO:0046549 retinal cone cell development(GO:0046549)
0.1 0.5 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.1 0.2 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.2 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.0 0.2 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0 0.2 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.0 0.3 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 0.2 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
0.0 0.6 GO:0030049 muscle filament sliding(GO:0030049)
0.0 0.6 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.0 0.2 GO:1902606 negative regulation of inositol phosphate biosynthetic process(GO:0010920) regulation of large conductance calcium-activated potassium channel activity(GO:1902606) positive regulation of large conductance calcium-activated potassium channel activity(GO:1902608)
0.0 0.2 GO:2001205 negative regulation of osteoclast development(GO:2001205)
0.0 0.1 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
0.0 1.3 GO:0071158 positive regulation of cell cycle arrest(GO:0071158)
0.0 0.3 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.2 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.2 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.1 GO:0034093 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.0 0.5 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.8 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.0 0.4 GO:0021702 cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.4 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.0 0.1 GO:1901678 iron coordination entity transport(GO:1901678)
0.0 0.3 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.4 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.2 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 0.9 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.7 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.2 GO:0071816 maintenance of unfolded protein(GO:0036506) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.0 0.4 GO:0006855 drug transmembrane transport(GO:0006855)
0.0 0.2 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.7 GO:0031935 regulation of chromatin silencing(GO:0031935)
0.0 0.3 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.0 0.5 GO:0032495 response to muramyl dipeptide(GO:0032495)
0.0 0.2 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.0 1.1 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.8 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 0.1 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
0.0 0.1 GO:2000864 estradiol secretion(GO:0035938) regulation of estradiol secretion(GO:2000864)
0.0 0.2 GO:0099628 receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
0.0 0.1 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.2 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.1 GO:0051660 establishment of centrosome localization(GO:0051660)
0.0 0.1 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.1 GO:0010825 positive regulation of centrosome duplication(GO:0010825)
0.0 0.1 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 5.2 GO:0097450 astrocyte end-foot(GO:0097450)
0.4 1.7 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.3 6.2 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.2 0.9 GO:0044301 climbing fiber(GO:0044301)
0.1 0.8 GO:0031262 Ndc80 complex(GO:0031262)
0.1 0.5 GO:0032021 NELF complex(GO:0032021)
0.1 0.8 GO:0097452 GAIT complex(GO:0097452)
0.1 0.4 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 0.7 GO:0070522 ERCC4-ERCC1 complex(GO:0070522)
0.1 4.6 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 0.4 GO:1990393 3M complex(GO:1990393)
0.1 0.3 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.1 1.1 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.1 GO:0005608 laminin-3 complex(GO:0005608)
0.0 0.3 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.7 GO:0070938 contractile ring(GO:0070938)
0.0 0.7 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.3 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.3 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.7 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 1.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.6 GO:0032982 myosin filament(GO:0032982)
0.0 1.0 GO:0045095 keratin filament(GO:0045095)
0.0 0.5 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.8 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.1 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.2 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.5 GO:0061702 inflammasome complex(GO:0061702)
0.0 0.4 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.9 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.2 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 1.8 GO:0005901 caveola(GO:0005901)
0.0 0.2 GO:0031464 Cul2-RING ubiquitin ligase complex(GO:0031462) Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.4 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.5 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.1 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 5.9 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.4 1.8 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.3 1.3 GO:0038025 reelin receptor activity(GO:0038025)
0.3 7.2 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.2 0.7 GO:0033883 pyridoxal phosphatase activity(GO:0033883)
0.2 0.4 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.2 1.7 GO:1903136 cuprous ion binding(GO:1903136)
0.2 0.5 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.2 0.9 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.1 0.6 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 0.7 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.1 0.4 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 0.3 GO:0042015 interleukin-20 binding(GO:0042015)
0.1 0.8 GO:0005095 GTPase inhibitor activity(GO:0005095) Roundabout binding(GO:0048495)
0.1 0.3 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.1 1.0 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 0.2 GO:0030629 rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) U6 snRNA 3'-end binding(GO:0030629)
0.1 0.3 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 2.1 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 0.3 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.2 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.1 0.8 GO:0031386 protein tag(GO:0031386)
0.0 1.2 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.2 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.0 4.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.1 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
0.0 0.9 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.6 GO:0031432 titin binding(GO:0031432)
0.0 0.2 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 1.0 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.2 GO:1904315 GABA-gated chloride ion channel activity(GO:0022851) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.2 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 2.4 GO:0097110 scaffold protein binding(GO:0097110)
0.0 1.0 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.3 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.1 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 1.1 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.7 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.2 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 1.5 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.9 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 0.4 GO:0015464 acetylcholine receptor activity(GO:0015464)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 1.9 GO:0005179 hormone activity(GO:0005179)
0.0 0.8 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.3 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.1 GO:2001069 glycogen binding(GO:2001069)
0.0 0.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 1.0 GO:0019894 kinesin binding(GO:0019894)
0.0 2.4 GO:0008201 heparin binding(GO:0008201)
0.0 0.4 GO:0015238 drug transmembrane transporter activity(GO:0015238)
0.0 0.2 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.3 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.2 GO:0008143 poly(A) binding(GO:0008143)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.8 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 1.5 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 1.4 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 1.0 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.7 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.6 PID CONE PATHWAY Visual signal transduction: Cones
0.0 1.0 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.6 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.2 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 1.8 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 2.0 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.6 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.8 PID PLK1 PATHWAY PLK1 signaling events
0.0 2.4 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.4 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.1 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.1 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.1 1.0 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.1 0.8 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 0.7 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.1 1.5 REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION Genes involved in Nuclear Events (kinase and transcription factor activation)
0.1 1.3 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.9 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.2 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.7 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 1.9 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 1.8 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.6 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 1.7 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.5 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.4 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.6 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.6 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.5 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.8 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.2 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.2 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.6 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.2 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.3 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor